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Articoli di riviste sul tema "Stem cells – Research"

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Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 31 gennaio 2023

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1

Rahat, Hashmi, e Ahmad Fahim. "Stem Cells: A Gold Mine in Dental Research and Tissue Engineering". Cancer Medicine Journal 2, n. 2 (31 dicembre 2019): 41–44. http://dx.doi.org/10.46619/cmj.2019.2-1012.

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The explosion of articles not only in scientific journals, but also in the print media and continuous TV debates, one could easily say the term “stem cells” has become synonym to the word “cure”. The extraordinary advances in the prevention, diagnosis, and treatment of human diseases, such as oral health issues, cancer, heart disease, diabetes and diseases of the central and peripheral nervous system, such as Parkinson's disease and Alzheimer's disease, continues to deprive people of health and well-being. Tremendous effort and exceptional research in human developmental biology has led to the identification and discovery of human stem cells.

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2

Stojkovic, Miodrag, Mark F. Pittenger, Jan A. Nolta, Majlinda Lako, T. R. J. Lappin e Martin J. Murphy. "STEM CELLS' Position Statement on hESC Research". STEM CELLS 28, n. 9 (settembre 2010): 1A. http://dx.doi.org/10.1002/stem.517.

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3

Caulfield, Timothy, Kalina Kamenova, Ubaka Ogbogu, Amy Zarzeczny, Jay Baltz, Shelly Benjaminy, Paul A. Cassar et al. "Research ethics and stem cells". EMBO reports 16, n. 1 (4 dicembre 2014): 2–6. http://dx.doi.org/10.15252/embr.201439819.

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4

Ikram, Huma, Darakhshan Jabeen Haleem, Zia Choudhry e Adnan Maqsood Choudhry. "Stem cells in Parkinson's research". El Mednifico Journal 1, n. 3 (7 ottobre 2013): 77. http://dx.doi.org/10.18035/emj.v1i3.39.

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5

King, Anthony. "Stem cells: highlights from research". Nature 597, n. 7878 (29 settembre 2021): S6—S7. http://dx.doi.org/10.1038/d41586-021-02621-4.

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6

Bolt, Hermann M. "Stem cells in toxicological research". Archives of Toxicology 91, n. 12 (15 novembre 2017): 4029–30. http://dx.doi.org/10.1007/s00204-017-2120-9.

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7

Grisham, Julie. "Stem cells as research tools". Nature Biotechnology 18, n. 4 (aprile 2000): 366. http://dx.doi.org/10.1038/74350.

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8

Holden, C. "STEM CELLS: U.S. Public Supports Stem Cell Research". Science 310, n. 5747 (21 ottobre 2005): 416b. http://dx.doi.org/10.1126/science.310.5747.416b.

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9

Holden, C. "STEM CELL RESEARCH: Primate Parthenotes Yield Stem Cells". Science 295, n. 5556 (1 febbraio 2002): 779a—780. http://dx.doi.org/10.1126/science.295.5556.779a.

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10

Revel, Michel. "Research on Human embryonic stem cells and cloning for stem cells". Human Reproduction & Genetic Ethics 14, n. 1 (29 luglio 2008): 4–14. http://dx.doi.org/10.1558/hrge.v14i1.4.

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11

Lane, Steven W., e D. Gary Gilliland. "Leukemia stem cells". Seminars in Cancer Biology 20, n. 2 (aprile 2010): 71–76. http://dx.doi.org/10.1016/j.semcancer.2009.12.001.

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12

Hernandez-Vargas, Hector, Nino Sincic, Maria Ouzounova e Zdenko Herceg. "Epigenetic signatures in stem cells and cancer stem cells". Epigenomics 1, n. 2 (dicembre 2009): 261–80. http://dx.doi.org/10.2217/epi.09.19.

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13

Shackleton, Mark. "Normal stem cells and cancer stem cells: similar and different". Seminars in Cancer Biology 20, n. 2 (aprile 2010): 85–92. http://dx.doi.org/10.1016/j.semcancer.2010.04.002.

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14

Alswailem, Abdulaziz M. "Stem Cells in Research: Islamic Perspectives". QScience Proceedings 2012, n. 1 (5 marzo 2012): 15. http://dx.doi.org/10.5339/qproc.2012.stem.1.15.

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15

He, H., M. R. Emmett, A. G. Marshall, Y. Ji, C. A. Conrad, W. Priebe, H. Colman et al. "Stem Cells". Neuro-Oncology 12, Supplement 4 (21 ottobre 2010): iv119—iv127. http://dx.doi.org/10.1093/neuonc/noq116.s18.

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16

Cheng, L., Z. Huang, W. Zhou, Q. Wu, J. Rich, S. Bao, P. Baxter et al. "STEM CELLS". Neuro-Oncology 15, suppl 3 (1 novembre 2013): iii206—iii216. http://dx.doi.org/10.1093/neuonc/not190.

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17

Hur, Min-Hee, Gabriela Dontu e Max S. Wicha. "Cancer Stem Cells". Journal of Breast Cancer 10, n. 3 (2007): 173. http://dx.doi.org/10.4048/jbc.2007.10.3.173.

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18

Wagner, Erwin F. "Embryonic stem cells". Current Opinion in Oncology 4 (dicembre 1992): S2—S4. http://dx.doi.org/10.1097/00001622-199212001-00002.

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19

Ghiaur, Gabriel, Jonathan M. Gerber, William Matsui e Richard J. Jones. "Cancer stem cells". Current Opinion in Oncology 24, n. 2 (marzo 2012): 170–75. http://dx.doi.org/10.1097/cco.0b013e32834ec015.

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20

Goymer, Patrick. "Sensitizing stem cells". Nature Reviews Cancer 8, n. 4 (aprile 2008): 246–47. http://dx.doi.org/10.1038/nrc2358.

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21

Fan, Xing, e Charles G. Eberhart. "Medulloblastoma Stem Cells". Journal of Clinical Oncology 26, n. 17 (10 giugno 2008): 2821–27. http://dx.doi.org/10.1200/jco.2007.15.2264.

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Abstract (sommario):

Medulloblastoma and other embronal brain tumors are similar in appearance and differentiation potential to neural stem and progenitor cells. Expression studies performed using human tumor samples, as well as the analysis of murine transgenic models, suggest that both multipotent cerebellar stem cells and lineage-restricted progenitors of the external germinal layer can be transformed into medulloblastoma by genetic alterations. These molecular changes frequently involve constitutive activation of signaling pathways such as Wnt, Hedgehog, and Notch, which play a key role in non-neoplastic neural stem cells. Pharmacologic blockade of the Hedgehog and Notch pathways suppresses the growth of medulloblastoma in culture and in vivo and may prove effective in targeting the small cancer stem-cell subpopulation required for tumor initiation and long-term propagation.

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22

Buss, Eike C., e Anthony D. Ho. "Leukemia stem cells". International Journal of Cancer 129, n. 10 (14 settembre 2011): 2328–36. http://dx.doi.org/10.1002/ijc.26318.

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23

Finkel, E. "Research Update: Neural Cells Cultured from Stem Cells". JNCI Journal of the National Cancer Institute 94, n. 2 (16 gennaio 2002): 87. http://dx.doi.org/10.1093/jnci/94.2.87.

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24

Daley, George Q. "Deriving blood stem cells from pluripotent stem cells for research and therapy". Best Practice & Research Clinical Haematology 27, n. 3-4 (settembre 2014): 293–97. http://dx.doi.org/10.1016/j.beha.2014.10.013.

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25

Hayashi, Yohei, e Evgeniia Borisova. "Disease-Focused Research Using Stem Cells". Biomedicines 9, n. 11 (8 novembre 2021): 1643. http://dx.doi.org/10.3390/biomedicines9111643.

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26

Jaworska, Dagmara, Wojciech Król e Ewelina Szliszka. "Prostate Cancer Stem Cells: Research Advances". International Journal of Molecular Sciences 16, n. 11 (17 novembre 2015): 27433–49. http://dx.doi.org/10.3390/ijms161126036.

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27

Okamoto, Oswaldo Keith, Ander Matheu e Luca Magnani. "Stem Cells in Translational Cancer Research". Stem Cells International 2015 (2015): 1–2. http://dx.doi.org/10.1155/2015/281072.

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28

Powledge, Tabitha M. "Research on human embryonic stem cells". EMBO reports 1, n. 4 (ottobre 2000): 297–98. http://dx.doi.org/10.1093/embo-reports/kvd084.

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29

Soria, Bernat, Francisco J. Bedoya e Franz Martin. "Gastrointestinal Stem Cells I. Pancreatic stem cells". American Journal of Physiology-Gastrointestinal and Liver Physiology 289, n. 2 (agosto 2005): G177—G180. http://dx.doi.org/10.1152/ajpgi.00116.2005.

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Abstract (sommario):

The transplantation of islets isolated from donor pancreas has renewed the interest in cell therapy for the treatment of diabetes. In addition, the capacity that stem cells have to differentiate into a wide variety of cell types makes their use ideal to generate β-cells for transplantation therapies. Several studies have reported the generation of insulin-secreting cells from embryonic and adult stem cells that normalized blood glucose values when transplanted into diabetic animal models. Finally, although much work remains to be done, there is sufficient evidence to warrant continued efforts on stem cell research to cure diabetes.

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30

Forsberg, E. Camilla, Deepta Bhattacharya e Irving L. Weissman. "Hematopoietic stem cells". Stem Cell Reviews 2, n. 1 (marzo 2006): 23–30. http://dx.doi.org/10.1007/s12015-006-0005-z.

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31

Houghton, JeanMarie, Alexei Morozov, Iva Smirnova e Timothy C. Wang. "Stem cells and cancer". Seminars in Cancer Biology 17, n. 3 (giugno 2007): 191–203. http://dx.doi.org/10.1016/j.semcancer.2006.04.003.

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32

Ross, Robert A., e Barbara A. Spengler. "Human neuroblastoma stem cells". Seminars in Cancer Biology 17, n. 3 (giugno 2007): 241–47. http://dx.doi.org/10.1016/j.semcancer.2006.04.006.

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33

Taurin, Sebastien, e Haifa Alkhalifa. "Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses". Neoplasia 22, n. 12 (dicembre 2020): 663–78. http://dx.doi.org/10.1016/j.neo.2020.09.009.

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34

Trounson, Alan, Kyle Kolaja, Thomas Petersen, Klaus Weber, Maralee McVean e Kathleen A. Funk. "Stem Cell Research". International Journal of Toxicology 34, n. 4 (20 aprile 2015): 349–51. http://dx.doi.org/10.1177/1091581815581423.

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Stem cells have great potential in basic research and are being slowly integrated into toxicological research. This symposium provided an overview of the state of the field, stem cell models, described allogenic stem cell treatments and issues of immunogenicity associated with protein therapeutics, and tehn concentrated on stem cell uses in regenerative medicine focusing on lung and testing strategies on engineered tissues from a pathologist’s perspective.

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35

Ng, Ashley P. "Hematopoietic stem cells, progenitor cells and leukemic stem cells in adult myeloproliferative neoplasms". Leukemia & Lymphoma 54, n. 5 (24 ottobre 2012): 922–33. http://dx.doi.org/10.3109/10428194.2012.734615.

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36

Hassan, Ghmkin, Said M. Afify, Neha Nair, Kazuki Kumon, Amira Osman, Juan Du, Hager Mansour et al. "Hematopoietic Cells Derived from Cancer Stem Cells Generated from Mouse Induced Pluripotent Stem Cells". Cancers 12, n. 1 (29 dicembre 2019): 82. http://dx.doi.org/10.3390/cancers12010082.

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Cancer stem cells (CSCs) represent the subpopulation of cancer cells with the ability to differentiate into other cell phenotypes and initiated tumorigenesis. Previously, we reported generating CSCs from mouse induced pluripotent stem cells (miPSCs). Here, we investigated the ability of the CSCs to differentiate into hematopoietic cells. First, the primary cells were isolated from malignant tumors that were formed by the CSCs. Non-adherent cells (NACs) that arose from adherent cells were collected and their viability, as well as the morphology and expression of hematopoietic cell markers, were analyzed. Moreover, NACs were injected into the tail vein of busulfan conditioned Balb/c nude mice. Finally, CSCs were induced to differentiate to macrophages while using IL3 and SCF. The round nucleated NACs were found to be viable, positive for hematopoietic lineage markers and CD34, and expressed hematopoietic markers, just like homing to the bone marrow. When NACs were injected into mice, Wright–Giemsa staining showed that the number of white blood cells got higher than those in the control mice after four weeks. CSCs also showed the ability to differentiate toward macrophages. CSCs were demonstrated to have the potential to provide progenies with hematopoietic markers, morphology, and homing ability to the bone marrow, which could give new insight into the tumor microenvironment according to the plasticity of CSCs.

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37

Singh, Gyanesh. "Drosophila's contribution to stem cell research". F1000Research 4 (18 giugno 2015): 157. http://dx.doi.org/10.12688/f1000research.6611.1.

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The discovery of Drosophila stem cells with striking similarities to mammalian stem cells has brought new hope for stem cell research. A recent development in Drosophila stem cell research is bringing wider opportunities for contemporary stem cell biologists. In this regard, Drosophila germ cells are becoming a popular model of stem cell research. In several cases, genes that controlled Drosophila stem cells were later discovered to have functional homologs in mammalian stem cells. Like mammals, Drosophila germline stem cells (GSCs) are controlled by both intrinsic as well as external signals. Inside the Drosophila testes, germline and somatic stem cells form a cluster of cells (the hub). Hub cells depend on JAK-STAT signaling, and, in absence of this signal, they do not self-renew. In Drosophila, significant changes occur within the stem cell niche that contributes to a decline in stem cell number over time. In case of aging Drosophila, somatic niche cells show reduced DE-cadherin and unpaired (Upd) proteins. Unpaired proteins are known to directly decrease stem cell number within the niches, and, overexpression of upd within niche cells restored GSCs in older males also . Stem cells in the midgut of Drosophila are also very promising. Reduced Notch signaling was found to increase the number of midgut progenitor cells. On the other hand, activation of the Notch pathway decreased proliferation of these cells. Further research in this area should lead to the discovery of additional factors that regulate stem and progenitor cells in Drosophila.

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38

Singh, Gyanesh. "Drosophila's contribution to stem cell research". F1000Research 4 (2 agosto 2016): 157. http://dx.doi.org/10.12688/f1000research.6611.2.

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Abstract (sommario):

The discovery of Drosophila stem cells with striking similarities to mammalian stem cells has brought new hope for stem cell research. Recent developments in Drosophila stem cell research is bringing wider opportunities for contemporary stem cell biologists. In this regard, Drosophila germ cells are becoming a popular model of stem cell research. In several cases, genes that controlled Drosophila stem cells were later discovered to have functional homologs in mammalian stem cells. Like mammals, Drosophila germline stem cells (GSCs) are controlled by both intrinsic as well as external signals. Inside the Drosophila testes, germline and somatic stem cells form a cluster of cells (the hub). Hub cells depend on JAK-STAT signaling, and, in absence of this signal, they do not self-renew. In Drosophila, significant changes occur within the stem cell niche that contributes to a decline in stem cell number over time. In case of aging Drosophila, somatic niche cells show reduced DE-cadherin and unpaired (Upd) proteins. Unpaired proteins are known to directly decrease stem cell number within the niches, and, overexpression of upd within niche cells restored GSCs in older males also . Stem cells in the midgut of Drosophila are also very promising. Reduced Notch signaling was found to increase the number of midgut progenitor cells. On the other hand, activation of the Notch pathway decreased proliferation of these cells. Further research in this area should lead to the discovery of additional factors that regulate stem and progenitor cells in Drosophila.

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39

Zhang, Yiming, Binshen Chen, Peng Xu, Chunxiao Liu e Peng Huang. "Reprogramming Prostate Cancer Cells into Induced Pluripotent Stem Cells: a Promising Model of Prostate Cancer Stem Cell Research". Cellular Reprogramming 22, n. 5 (1 ottobre 2020): 262–68. http://dx.doi.org/10.1089/cell.2020.0032.

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40

Yasui, Wataru, Shin-Ichi Nishikawa e Eiichi Tahara. "Cancer stem cells." Cancer Science 98, n. 5 (maggio 2007): 753–56. http://dx.doi.org/10.1111/j.1349-7006.2007.00442.x.

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41

Schwarzenberger, Paul, Jay K. Kolls e Vincent La Russa. "Hematopoietic Stem Cells". Cancer Investigation 20, n. 1 (gennaio 2002): 124–38. http://dx.doi.org/10.1081/cnv-120000373.

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42

Reiffers, J., Ph Bernard, G. Vezon, A. Sarrat, G. Marit, B. David e A. Broustet. "Autologous transplantation with circulating stem cells : When to collect stem cells?" Leukemia Research 10, n. 1 (gennaio 1986): 118. http://dx.doi.org/10.1016/0145-2126(86)90205-5.

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43

SUTTER, R., G. YADIRGI e S. MARINO. "Neural stem cells, tumour stem cells and brain tumours: Dangerous relationships?" Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1776, n. 2 (dicembre 2007): 125–37. http://dx.doi.org/10.1016/j.bbcan.2007.07.006.

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44

Gallagher, Amy. "Research Shows Engineered NK Cells Eliminate Glioblastoma Stem Cells". Oncology Times 43, n. 14 (20 luglio 2021): 17. http://dx.doi.org/10.1097/01.cot.0000767448.11048.ed.

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45

Marcon, Alessandro R., Blake Murdoch e Timothy Caulfield. "Fake news portrayals of stem cells and stem cell research". Regenerative Medicine 12, n. 7 (ottobre 2017): 765–75. http://dx.doi.org/10.2217/rme-2017-0060.

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46

Ware, Carol B. "Naive embryonic stem cells: the future of stem cell research?" Regenerative Medicine 9, n. 4 (luglio 2014): 401–3. http://dx.doi.org/10.2217/rme.14.31.

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47

Leeb, C., M. Jurga, C. McGuckin, N. Forraz, C. Thallinger, R. Moriggl e L. Kenner. "New perspectives in stem cell research: beyond embryonic stem cells". Cell Proliferation 44 (aprile 2011): 9–14. http://dx.doi.org/10.1111/j.1365-2184.2010.00725.x.

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48

Seydel, C. "STEM CELL RESEARCH: Stem Cells May Shore Up Transplanted Hearts". Science 295, n. 5553 (11 gennaio 2002): 253b—254. http://dx.doi.org/10.1126/science.295.5553.253b.

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49

Vogel, G. "STEM CELL RESEARCH: Rat Brains Respond to Embryonic Stem Cells". Science 295, n. 5553 (11 gennaio 2002): 254b—255. http://dx.doi.org/10.1126/science.295.5553.254b.

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50

Hill, R. P., e R. Perris. ""Destemming" Cancer Stem Cells". JNCI Journal of the National Cancer Institute 99, n. 19 (25 settembre 2007): 1435–40. http://dx.doi.org/10.1093/jnci/djm136.

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