Letteratura scientifica selezionata sul tema "Staphylococcus aureus"

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Articoli di riviste sul tema "Staphylococcus aureus"

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Ondusko, Devlynne S., e Dawn Nolt. "Staphylococcus aureus". Pediatrics in Review 39, n. 6 (giugno 2018): 287–98. http://dx.doi.org/10.1542/pir.2017-0224.

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NAQVI, ZULFIQAR ALI, QAMAR AZIZ e ARIF MEMON. "STAPHYLOCOCCUS AUREUS;". Professional Medical Journal 20, n. 01 (10 dicembre 2012): 139–43. http://dx.doi.org/10.29309/tpmj/2013.20.01.587.

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Objective: To determine the prevalence of Staph. aureus in burn patients. Setting: Department of Microbiology, BasicMedical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. Period: July 2002 to December 2002. Material and Methods:Out of 52 patients 23 (44%) were found infected by 41 strains of S. aureus in which 10 strains were Methicillin resistant. Results: AllMethicillin sensitive and resistant strains were sensitive to Vancomycin and Chloramphenicol. Other effective drugs against MSSA wereImipenem (93.5%), Cephalothin (77.5%), Clindamycin (68%) while MRSA strains were highly resistant to all other drugs. Conclusions:Gram positive heavily colonize the wound at initial days following burn injury. Once Staph aureus specially MRSA establishing in burn unit,it is very difficult to eradicate these bacteria from burn unit. It is therefore all efforts must made to prevent burn patients from infectionspecially Staph. Aureus infection, by establising infection control team these burn units.
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SHEFF, BARBARA. "Staphylococcus aureus". Nursing 31, n. 9 (settembre 2001): 86. http://dx.doi.org/10.1097/00152193-200131090-00038.

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Pasachova Garzón, Jennifer, Sara Ramirez Martinez e L. Muñoz Molina. "Staphylococcus aureus". Nova 17, n. 32 (15 novembre 2019): 25–38. http://dx.doi.org/10.22490/24629448.3631.

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Staphylococcus aureus se caracteriza por ser la principal causa de bacteriemia nosocomial en el mundo, debido al incremento en la resistencia, a los diferentes factores de patogenicidad y virulencia y la expresión de una gran variedad de roteínas las cuales pertenecen a las moléculas de la matriz adhesiva (MSCRAMM), presentes en la superficie de la bacteria cuya función es la colonización e invasión celular al hospedero y favorecer la formación de biopelícula, El conjunto de estos mecanismos de patogenicidad y virulencia, le permiten a la bacteria persistir en el huésped y en el ambiente, sobreviviendo a factores adversos, al sistema inmune y a los antimicrobianos.
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Nimmo, Graeme, e Geoffrey W. Coombs. "Staphylococcus aureus". Microbiology Australia 29, n. 3 (2008): 113. http://dx.doi.org/10.1071/ma08113.

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Staphylococcus aureus is one of the major bacterial pathogens of man, causing a variety of diseases from mild skin and soft-tissue infections to severe invasive infections with high mortality. In the healthcare setting it is the most frequent cause of surgical site, lower respiratory tract and cardiovascular infections and the second most common cause of blood stream infections and pneumonia. The ability of S. aureus to develop resistance to all classes of antimicrobials, in particular the �-lactams, has become a major global problem. In the pre-antibiotic era, the mortality rate for severe staphylococcal sepsis was as high as 90%. In a recent meta-analysis of nine studies of S. aureus bacteraemia in the antibiotic era, although the mean mortality rate due to methicillin-susceptible S. aureus (MSSA) was 12% (ranging from 0 to 38%), for methicillin-resistant S. aureus (MRSA) the mean was 29% (ranging from 8 to 50%). Whilst estimates vary, the mortality associated with MRSA is on average twice that with MSSA.
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Bergdoll, Merlin S. "Staphylococcus aureus". Journal of AOAC INTERNATIONAL 74, n. 4 (1 luglio 1991): 706–10. http://dx.doi.org/10.1093/jaoac/74.4.706.

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Abstract The analytical methods for the detection of the staphylococcal enterotoxins can be divided into 2 categories: (1) methods for detection of enterotoxin-producing staphylococcal strains; (2) methods for detection of enterotoxin in foods. Gel diffusion methods (Ouchterlony, microslide), in which the enterotoxin produced by any given strain is compared to one of the identified enterotoxins, are used most frequently for strain testing. The sensitivity of these methods is from 0.1 to 0.5 μg enterotoxin/mL, which is normally adequate to determine the enterotoxigenicity of strains. The methods for the detection of enterotoxin in foods need to be much more sensitive to detect less than 1 ng of enterotoxin/g of food that may be present. The radioimmunoassay (RIA), the enzymelinked immunosorbent assay (ELISA), and the reversed passive latex agglutination (RPLA) method have the necessary sensitivity to detect 1 ng/g of enterotoxin in foods without the use of complicated extraction-concentration procedures. Kits based on the ELISA and RPLA methods are now available commercially for the detection of enterotoxins in foods. Tests have shown that the ELISA methods are somewhat more sensitive than the RPLA method.
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Eykyn, S. J., e R. H. Grace. "Staphylococcus aureus". Diseases of the Colon & Rectum 28, n. 10 (ottobre 1985): 758. http://dx.doi.org/10.1007/bf02560300.

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Davit Nugraha, Anna L. Yusuf, Veri Nugraha, Panji Wahlanto e Marlina Indriastuti. "AKTIVITAS ANTIBAKTERI AIR PERASAN BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus". Medical Sains : Jurnal Ilmiah Kefarmasian 7, n. 4 (18 ottobre 2022): 847–52. http://dx.doi.org/10.37874/ms.v7i4.470.

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Bakteri Staphylococus aureus merupakan bakteri patogen dan dapat menyebabkan infeksi mulai dari infeksi kulit ringan sampai dengan infeksi sistemik. Sebagian besar pada awal mulanya Staphylococus aureus peka terhadap penisilin, namun setelah meluasnya penggunaan penisilin ditemukan 65% sampai 85% Staphylococus aureus menghasilkan beta laktamase sehingga menjadi resisten terhadap penisilin G. Hal tersebut diatas mendorong pengobatan alternatif yang aman dan tidak menimbulkan resistensi untuk menanggulangi infeksi bakteri Staphylococus aureus. Perasan buah pepaya sering terdengar penggunaan dimasyarakat untuk pengobatan jerawat secara turun temurun, ini dimungkinkan perasan buah pepaya mempunyai efek anti bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui kemampuan daya hambat air perasan buah papaya (Carica Papaya L) terhadap bakteri Staphylococcus aureus. Metode pengujian daya hambat pada air perasan buah papaya menggunakan metode difusi agar dengan konsentrasi 20%, 40%, 60% dan 80%. Air perasan buah pepaya pada penelitian ini mempunyai kemampuan daya hambat yang sedang terhadap pertumbuhan bakteri Staphylococcus aureus, serta konsentrasi yang paling efektif sebesar 60%.
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Dinges, Martin M., Paul M. Orwin e Patrick M. Schlievert. "Exotoxins of Staphylococcus aureus". Clinical Microbiology Reviews 13, n. 1 (1 gennaio 2000): 16–34. http://dx.doi.org/10.1128/cmr.13.1.16.

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SUMMARY This article reviews the literature regarding the structure and function of two types of exotoxins expressed by Staphylococcus aureus, pyrogenic toxin superantigens (PTSAgs) and hemolysins. The molecular basis of PTSAg toxicity is presented in the context of two diseases known to be caused by these exotoxins: toxic shock syndrome and staphylococcal food poisoning. The family of staphylococcal PTSAgs presently includes toxic shock syndrome toxin-1 (TSST-1) and most of the staphylococcal enterotoxins (SEs) (SEA, SEB, SEC, SED, SEE, SEG, and SEH). As the name implies, the PTSAgs are multifunctional proteins that invariably exhibit lethal activity, pyrogenicity, superantigenicity, and the capacity to induce lethal hypersensitivity to endotoxin. Other properties exhibited by one or more staphylococcal PTSAgs include emetic activity (SEs) and penetration across mucosal barriers (TSST-1). A detailed review of the molecular mechanisms underlying the toxicity of the staphylococcal hemolysins is also presented.
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Achek, Rachid, Helmut Hotzel, Ibrahim Nabi, Souad Kechida, Djamila Mami, Nassima Didouh, Herbert Tomaso et al. "Phenotypic and Molecular Detection of Biofilm Formation in Staphylococcus aureus Isolated from Different Sources in Algeria". Pathogens 9, n. 2 (24 febbraio 2020): 153. http://dx.doi.org/10.3390/pathogens9020153.

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Staphylococcus aureus is an opportunistic bacterium causing a wide variety of diseases. Biofilm formation of Staphylococcus aureus is of primary public and animal health concern. The purposes of the present study were to investigate the ability of Staphylococcus aureus isolated from animals, humans, and food samples to form biofilms and to screen for the presence of biofilm-associated and regulatory genes. In total, 55 Staphylococcus aureus isolated from sheep mastitis cases (n = 28), humans (n = 19), and from food matrices (n = 8) were identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The ability of Staphylococcus aureus for slime production and biofilm formation was determined quantitatively. A DNA microarray examination was performed to detect adhesion genes (icaACD and biofilm-associated protein gene (bap)), genes encoding microbial surface components recognizing adhesive matrix molecules (MSCRAMMs), regulatory genes (accessory gene regulator (agr) and staphylococcal accessory regulator (sarA)), and the staphylococcal cassette chromosome mec elements (SCCmec). Out of 55 Staphylococcus aureus isolates, 39 (71.0%) and 23 (41.8%) were producing slime and biofilm, respectively. All Staphylococcus aureus strains isolated from food showed biofilm formation ability. 52.6% of the Staphylococcus aureus strains isolated from sheep with mastitis, and 17.9% of isolates from humans, were able to form a biofilm. Microarray analysis typed the Staphylococcus aureus into 15 clonal complexes. Among all Staphylococcus aureus isolates, four of the human isolates (21.1%) harbored the mecA gene (SCCmec type IV) typed into 2 clonal complexes (CC22-MRSA-IV and CC80-MRSA-IV) and were considered as methicillin-resistant, while two of them were slime-producing. None of the isolates from sheep with mastitis harbored the cna gene which is associated with biofilm production. The fnbB gene was found in 100%, 60% and 40% of biofilm-producing Staphylococcus aureus isolated from food, humans, and sheep with mastitis, respectively. Three agr groups were present and agr group III was predominant with 43.6%, followed by agr group I (38.2%), and agr group II (18.2%). This study revealed the capacity of Staphylococcus aureus isolates to form biofilms and highlighted the genetic background displayed by Staphylococcus aureus isolates from different sources in Algeria.
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Tesi sul tema "Staphylococcus aureus"

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Messad, Nourreddine. "Staphylococcus aureus colonisant / Staphylococcus aureus infectant dans le modèle du pied diabétique". Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT063/document.

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Staphylococcus aureus est l’un des principaux agents étiologiques des infections suppuratives superficielles et profondes ainsi que des syndromes liés à l’action de toxines. Paradoxalement, cette bactérie est un agent commensal qui est présent sur la peau ainsi que dans les cavités nasales notamment. Cela permet de considérer cette bactérie comme un organisme colonisant commensale. Les bases génétiques expliquant la différence entre une bactérie pathogène et une bactérie commensale reste inconnues. En utilisant la technique Optical Maps sur des souches de S. aureus isolées de plaies de pieds diabétiques avec différents niveau de virulence, nous avons pu montrer l’existence d’un prophage insérés dans le génome des souches colonisantes et absent des souches infectantes. Le phage, nommé ROSA, est localisé dans un hotspot d’insertion de phage NM2. Il est aussi localisé en amont du locus isd qui est requis pour l’assimilation du fer essentiel à la bactérie dans sa phase pathogène. Le phage ROSA inactive la voie isd en dérégulant l’activité du régulateur transcriptionnel majeur Fur en absence de fer. Il réduit aussi la virulence de ces souches sur les 2 modèles de virulence (Le ver C. elegans et le Zebrafish). L’expulsion du phage ROSA restaure la régulation du locus isd par Fur et la production de sidérophores en absence de Fer, la formation du biofilm et la virulence des souches. La mutation du gène Fur nous a permis de déduire que le phage ROSA affectait les bactéries de manière indépendante de Fur. Enfin, nous avons étudié la prévalence des souches colonisantes sur les plaies de pieds diabétiques. Nous avons observé que 20% des souches présentait l’insertion ROSA et 89% appartenait au complexe clonal CC8. Les souches colonisantes, avec leur niveau bas de virulence, devraient faire l’objet de détection dans le but de rationnaliser l’utilisation des antibiotiques et ainsi lutter contre l’apparition de bactéries multirésistantes aux antibiotiques
Staphylococcus aureus is an opportunistic bacterium capable of causing a wide range of severe diseases when it gains access to underlying tissues. Paradoxically, this causative pathogen is a common inhabitant of the skin microflora and colonizes the nares and other human mucosa, and as such, may be considered as a commensal colonizing organism. The genetic basis for the differences in pathogenic/colonizing potential is unknown. By performing optical maps comparisons of a collection of S. aureus strains of defined virulence potential isolated from diabetic foot ulcers at different stages, we brought to light a prophage present in colonizing-causing bacteria. The phage, namely ROSA, was localized in a hotspot region NM2 near the locus isd, the main iron surface determinant that transport iron across the bacterial wall. It induces a deregulation of the activity of the transcriptional regulator Fur involving the biofilm formation of the bacteria in response to low iron environment. It reduced also significantly the virulence of the strain in two in vivo models (the nematode C. elegans and the zebrafish). The expulsion of the phage restored the regulation of the locus isd, the siderophore production, the biofilm formation and the virulence of the strain. The mutation of the fur gene within the colonizing strain enabled us to determine that the phage ROSA affect the the bacteria in a Fur-independent manner. Finally we determined the prevalence of these colonizing strains in skin and soft tissue infections (diabetic foot ulcers). We observed that 20% (39/195) of the strains harboured this insertion and 89% belonged to the clonal complex CC8. This colonizing strain by its low virulence potential must be detected in the aim to contribute to a sounder use of antibiotic treatment, an important point in front of the increase of multidrug resistant bacteria
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Pourkomailian, B. "Osmoregulation in Staphylococcus aureus". Thesis, University of Aberdeen, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593300.

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Osmoregulation in Staphylococcus aureus has been studied. Glycine betaine was found to act as an osmoprotectant by stimulating specific growth rate and salt tolerance of osmotically stressed S. aureus cells. The accumulation of this compatible solute was accomplished via two constitutive Na+ dependant transport systems, a high-affinity system (Km = 3μM; Vmax = 26nmol. min-1 mg total protein-1) and a low-affinity system (Km = 133μM; Vmax = 155 nmol. min-1 mg total protein-1). The high-affinity system is specific for glycine betaine and its activity is not greatly stimulated by osmotic pressure. The low-affinity sytem transports proline and proline analogues and its activity is stimulated by increases in external osmolarity. Proline transport is achieved via two similar systems. Through transposon mutagenesis it was demonstrated that the low-affinity glycine betaine transport system and the low-affinity proline transport system are the same system. The low-affinity system is the major system responsible for the accumulation of glycine betaine. This is the more important system for the osmoregulation strategy of S. aureus. All three transport systems have been demonstrated to be subject to feedback regulation. The internal compatible solute concentration dictates the level of activity of the transport systems. A mutant has been isolated that lacks the low-affinity system and the high-affinity proline transport system.
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Lucet, Jean-Christophe. "Epidémiologie de Staphylococcus aureus". Paris 11, 2004. http://www.theses.fr/2004PA114817.

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Ce travail a cherché à établir l'importance du réservoir méconnu des porteurs de Staphylococccus aureus résistant à la méticilline (SARM) dans l'épidémiologie hospitalière de cette bactérie multirésistante aux antibiotiques, la plus fréquente en France. Il montre au travers d'enquêtes prospectives, que la prévalence et l'incidence du SARM sont beaucoup plus elévées que ne laissent penser les surveillances basées sur des prélèvements à visée clinique. Il établit des facteurs de risque de portage de SARM, et suggère enfin que la stratégie de dépistage et précautions " contact " est efficace. Le contrôle de la dissémination manuportée du SARM doit inclure une stratégie raisonnée de dépistage des porteurs
Our research aimed to determine the significance of unknown carriage of methicillin-resistant Staphylococcus aureus in the epidemiology of this multiply-resistant strains in the hospital setting. Through prospective observational studies of MRSA carriage, we demonstrated that incidence and prevalence of MRSA at hospital admission are much higher than that estimated by clinical isolates only. We established parameters associated with MRSA carriage, and suggested that active surveillance screening and contact precautions are valuable in the ICU setting. Controlling the hospital spread of MRSA should include a judicious strategy for screening MRSA
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Zhang, Lihong. "Studies on protein Sbi in Staphylococcus aureus /". Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/avh/2000/91-576-5780-7.pdf.

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Chaibenjawong, Plykaeow. "Desiccation Tolerance in Staphylococcus aureus". Thesis, University of Sheffield, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522502.

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Libberton, Andrew Benjamin. "The ecology of Staphylococcus aureus". Thesis, University of Liverpool, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569556.

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Nasal carriage of Stephvtococcue aureus is associated with increased risk of infection in humans. Several factors are known to affect carriage including host genetics and S. aureus immune evasion. However while members of the microbial community have been shown to affect S. aureus nasal colonisation individually, relatively little work has been done to understand how and why nasal microbial community as a whole, affects carriage of S. aureus. Here, the cultivable bacteria from 60 anterior nares communities were sampled and identified to species level using apiSTAPH and 16S rRNA gene sequencing. The taxa distributions across communities revealed negative associations of S. aureus with the following taxa: S. capitis, Corynebacterium propinquum, C. macgin/eyi, Enterobacter aerogenes, S. epidermidis, Micrococcus sp., Bacillus sp., C. acco/ens, S. schleiferi and Gemella haemo/ysans. Since toxin-mediated interference can affect community composition, nasal isolates were screened for their ability to inhibit growth of S. aureus on a solid medium. Overlaying this inhibition data onto community taxa distributions revealed that negative associations between S. aureus and S. epidermidis, S. capitis, C. propinquum, C. acco/ens and a Micrococcus sp. were potentially driven by toxin- mediated interference competition. Moreover novel negative associates were found between S. aureus and an inhibitory subset of Micrococcus /uteus and S. hominis. By also measuring the cumulative inhibition of entire natural communities, it was possible to show that S. aureus was less frequent in highly inhibitory microbial communities. The quorum sensing mechanism, encoded by the agr locus, and biofilm formation have been proposed to play an important role in nasal colonisation of S. aureus. Therefore to further investigate community dynamics, S. capitis, S. epidermidis and corynebacteria isolates were assayed for their ability to interfere with Agr signaling and biofilm formation. No evidence was obtained to indicate that biofilm interference by these species affected the distribution of S. aureus across communities. By contrast, S. epidermidis isolates that interfered with Agr signaling were significantly more likely to coexist with S. aureus, and S. capitis isolates interfering with Agr signaling were significantly less likely to coexist with S. aureus. In theory, toxin-mediated interference competition can act both to protect producers against invasion, and, conversely, to promote the invasion of producers into an occupied niche. An experimental ecology approach was used to show that S. aureus is less likely to invade an inhibitor-producing S. epidermidis population than a non-inhibitor-producing population, especially on a spatially-structured medium. Furthermore, inhibitor-producing populations of S. epidermidis invade more successfully than non-inhibitor-producers, although they do not displace the S. aureus resident due to evolution of toxin resistance. There is also evidence of eo- evolution where inhibitor-producing strains of S. epidermidis can evolve stronger inhibitory activity when invading sensitive S. aureus populations that evolve resistance. These findings could impact the future treatment of S. aureus infections and help to control nasal carriage.
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Monk, Alastair Brian. "Staphylococcus aureus : evolution and epidemiology". Thesis, University of Bath, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413068.

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Jones, Eleanor. "Osmotic adaptations of Staphylococcus aureus". Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310928.

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Chaffey, Brian John. "The adhesion of Staphylococcus aureus". Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306699.

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Horsburgh, Malcolm James. "Chorismate synthase from Staphylococcus aureus". Thesis, University of Glasgow, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297034.

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Libri sul tema "Staphylococcus aureus"

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Rice, Kelly C., a cura di. Staphylococcus aureus. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1550-8.

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Bagnoli, Fabio, Rino Rappuoli e Guido Grandi, a cura di. Staphylococcus aureus. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-72063-0.

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Nakane, Akio, e Krisana Asano, a cura di. Staphylococcus aureus. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1.

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D, Freeman-Cook Kevin, a cura di. Staphylococcus aureus infections. Philadelphia: Chelsea House Publishers, 2005.

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Freeman-Cook, Lisa. Staphylococcus aureus infections. A cura di Freeman-Cook Kevin D, Alcamo I. Edward e Heymann David L. Philadelphia: Chelsea House Publishers, 2006.

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A, Ala'Aldeen Dlawer A., e Hiramatsu Keiichi 1949-, a cura di. Staphylococcus aureus: Molecular and clinical aspects. Chichester, U.K: Horwood Pub., 2004.

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National Veterinary Institute (Uppsala, Sweden) e Sveriges langbruksuniversitet. Veterinärmedicinska fakulteten. Department of Veterinary Microbiology. Section of Bacteriology and Epizootology, a cura di. Virulence determinants of Staphylococcus aureus: Virulence studies of alpha-toxin, coagulase, and protein A mutants and recombinants and studies of cell-surface hydrophobicity. Uppsala, Sweden: Dept. of Veterinary Microbiology, Section of Bacteriology and Epizootology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, 1986.

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Honeyman, Allen L., Herman Friedman e Mauro Bendinelli, a cura di. Staphylococcus aureus Infection and Disease. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/b111097.

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Allen, Honeyman, Friedman Herman 1931- e Bendinelli Mauro, a cura di. Staphylococcus aureus infection and disease. New York: Kluwer Academic/Plenum, 2001.

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Yinduo, Ji. Methicillin-Resistant Staphylococcus aureus (MRSA) Protocols. New Jersey: Humana Press, 2007. http://dx.doi.org/10.1385/1597454680.

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Capitoli di libri sul tema "Staphylococcus aureus"

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Nakane, Akio, e Phawinee Subsomwong. "Immune Response to Staphylococcus aureus". In Staphylococcus aureus, 151–86. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_5.

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Becker, Karsten. "Colonization and Persistence Strategies of Staphylococcus aureus". In Staphylococcus aureus, 1–40. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_1.

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Hu, Dong-Liang, Hisaya K. Ono, Shaowen Li e Rendong Fang. "Exotoxins of Staphylococcus aureus". In Staphylococcus aureus, 81–117. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_3.

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Sato’o, Yusuke. "Staphylococcus aureus Pathogenesis Based on Genetic Background". In Staphylococcus aureus, 119–50. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_4.

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Foster, Timothy J. "Cell Wall-Anchored Surface Proteins of Staphylococcus aureus". In Staphylococcus aureus, 41–80. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_2.

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Asano, Krisana. "Immune Evasion and Interaction Between Autophagy and Intracellular Staphylococcus aureus". In Staphylococcus aureus, 187–99. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_6.

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Iandolo, John J., e George C. Stewart. "Staphylococcus aureus". In Bacterial Genomes, 743–53. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-6369-3_80.

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Becker, Karsten, e Georg Peters. "Staphylococcus aureus". In Lexikon der Infektionskrankheiten des Menschen, 762–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-39026-8_1041.

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Bennett, Reginald W., Jennifer M. Hait e Sandra M. Tallent. "Staphylococcus aureus". In Guide to Foodborne Pathogens, 26–44. Oxford: John Wiley & Sons, 2013. http://dx.doi.org/10.1002/9781118684856.ch2.

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da Silva, Neusely, Marta Hiromi Taniwaki, Valéria Christina Amstalden Junqueira, Neliane Ferraz de Arruda Silveira, Margarete Midori Okazaki e Renato Abeilar Romeiro Gomes. "Staphylococcus aureus". In Microbiological Examination Methods of Food and Water, 135–47. Second edition. | Leiden, The Netherlands ; Boca Raton : CRC Press/Balkema, [2018]: CRC Press, 2018. http://dx.doi.org/10.1201/9781315165011-10.

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Atti di convegni sul tema "Staphylococcus aureus"

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Kiranasari, Ariyani, Angela Bonita, Elizabeth Melina, Kevin Winston, Naivedh Baht, Nathania Sutandi, Beti Ernawati Dewi, Ika Ningsih e Fithriyah Sjatha. "Antibacterial Activity of Several Indonesian Endemic Plants against Staphylococcus epidermidis, Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus". In Bromo Conference, Symposium on Natural Products and Biodiversity. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008359501780182.

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Cristina, Gisele Pereira Rodrigues e. Lilia, LILIA CRISTINA A. G. DE PAULA e GISELE PREIRA RODRIGUES. "STAPHYLOCOCCUS AUREUS NO AMBIENTE HOSPITALAR". In IV Congresso Brasileiro de Ciências Biológicas On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2023. http://dx.doi.org/10.51189/conbracib2023/16933.

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Himelbloom, B. H. "Staphylococcus aureus concerns in smoked fish". In International Smoked Seafood Conference. Alaska Sea Grant, University of Alaska Fairbanks, 2008. http://dx.doi.org/10.4027/isscp.2008.03.

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Adams, Kelly M., Valsamma Abraham, Daniel Spielman, Noam Cohen, Jay K. Kolls e James L. Kreindler. "Pendrin Expression In Staphylococcus Aureus Pneumonia". In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3532.

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Blajan, Marius, Ahmad Guji Yahaya, Jaroslav Kristof, Tomohiro Okuyama e Kazuo Shimizu. "Inactivation of Staphylococcus Aureus by Microplasma". In 2021 IEEE Industry Applications Society Annual Meeting (IAS). IEEE, 2021. http://dx.doi.org/10.1109/ias48185.2021.9677085.

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Habibović, Selma, Aleksandra Jovanović e Snežana Ribis. "Staphylococcus aureus, the most prevalent isolate among surgically treated patients". In Proceedings of the International Congress Public Health - Achievements and Challenges, 165. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24118h.

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Background and Objective: According to available research data, one of the greatest treats for surgical departments is presence of chronical staphylococcal infections in patients admitted for hospital treatment. These infections can be caused by wild-type strains, but also resistant strains of this bacteria gained after frequent hospital treatments. Any of these strains in hospital environment has a plenty possibility for further evolution, which mainly can be modified by proper or inappropriate usage of antibiotics. The goal of our research was to explore the variety of microbes present in wounds after surgical treatment and their susceptibility to antibiotics. Methods: Our investigation was conducted as a retrospective study in Public Health Institute Novi Pazar from July 2021 to January 2022. The study outlined 183 bacterial isolates from surgical wounds of 94 inpatients and 89 outpatients. Identification of isolated bacteria has been performed using conventional microbiological techniques and susceptibility testing was done according to the EUCAST standards. Results: The most prevalent isolate was Staphylococcus aureus (35%), present in 13.7% of inpatients wounds and 21.3% of outpatients' wounds. It was followed by Klebsiella spp. (22.4%), Escherichia coli (15.8%) and Pseudomonas aeruginosa (8.2%). Among inpatients, Staphylococcus aureus dominated infections of wounds after Cesarean section (29.7% of all its isolates). Compared to the outpatients, Staphylococcus aureus was predominantly found in wounds of inpatients after genitourinary surgery, including Cesarean section. However, all together, the most frequently it was present in wounds of outpatients after surgical interventions (orthopedic, vascular, general, abdominal, chest and plastic surgery). Meticillin-resistant strains of Staphylococcus aureus were generally detected in wounds of inpatients, except orthopedic outpatients, where the wounds have been mostly affected by trauma or chronical infection presence. Conclusion: Hospital-acquired infections are of great importance, particularly in light of the rapid increase in bacterial resistance. In this regard, it is essential to study roots of their spreading as well as to detect weak points of established antimicrobial therapy protocols in tertiary health care units.
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Omar Mohammed, Mohammed Shaymaa, Nicoleta Radu, Verginica Schroder, Rodica Roxana Constantinescu e Narcisa Babeanu. "Antimicrobial Properties of the Bioproducts Formulated with Chitosan and Collagen". In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.ii.17.

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Three types of formulations (stable suspensions) based on collagen, chitosan, limonene and an imidazole derivative were studied through in vitro tests, from the point of view of antimicrobial activity. The results obtained on 4 standardized microorganisms, namely Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus aureus MRSA, Candida albicans, demonstrated that most of the obtained bioproducts have a local effect (inhibition diameters below 15 mm are obtained) and moderate effect (inhibition diameters located under 20 mm), except bioproducts containing collagen, chitosan, limonene and an imidazole derivative (antibiotic reagent) in mass ratio Col:Chit:Lim:CT=1:1:1:0.1, Col:Chit:Lim:CT=1:1:0:0.1 which exhibit a significant antimicrobial effect on Staphylococcus aureus and Staphylococcus aureus MRSA. These two formulations also exhibit significant antimicrobial effects for Candida albicans, for which the average inhibition diameters obtained are greater than 34 mm.
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Apolinário, Joelma Maria dos Santos da Silva. "CARACTERÍSTICAS CLASSIFICAÇÃO E PATOGENICIDADE DO STAPHYLOCOCCUS AUREUS". In I Congresso Nacional de Microbiologia Clínica On-Line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/1211.

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Introdução: O S. aureus trata-se de uma bactéria Gram-positiva onde suas células têm forma de cocos, apresentam-se frequentemente agrupados em cacho e são imóveis. Em condições favoráveis, produz toxinas – enterotoxinas – que são o agente responsável pela intoxicação alimentar. Os fatores de patogenicidade associados a bactéria são; adesinas e formação de biofilme. Outros fatores como invasinas (proteases, lipases) e toxinas, também tem sido bastante estudados. Considerando a habilidade das bactérias produzirem o filme extracelular in vitro, propõe-se uma marca de patogenicidade associando ser um organismo virulento. Objetivo: Avaliar seus fatores características e patogenicidade bem como pesquisar a sua capacidade produtora de enterotoxina. Metodologia: O presente trabalho configurou-se com um estudo de caso através da revisão sistemática da literatura, que possibilitou a construção de referencial teórico sobre assuntos que estão relacionados ao tema em questão, utilizando dados de artigos científicos das plataformas digitais PubMed (National Library of Medicine) e SciELO (Scientific Electronic Library Online). Resultados: As espécies de Staphylococcus podem ser classificadas em dois grupos de acordo com a presença ou ausência da enzima coagulase. Assim, as espécies que possuem a enzima são denominadas coagulase positiva, sendo o Staphylococcus aureus a única espécie desse grupo, e as espécies que não possuem são chamadas de estafilococos coagulase negativa. Conclusão: As enterotoxinas produzidas por S. aureus podem estar relacionadas com o agravamento das doenças causadas pelo micro-organismo, além da sua habilidade de causar intoxicação alimentar, dessa forma constata-se que a bactéria é um dos principais patógenos de maior patogenicidade alta ocorrência e morbidade das infecções por este ocasionado.
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McDowell, Susan A., Yan Ma e Henry T. Akinbi. "Simvastatin Is Protective During Staphylococcus Aureus Pneumonia". In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6157.

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Furtado, Janaise Mesquita Bueno, Charlene Nascimento Dos Santos Trindade, Everton Granemann Souza, Mário Lúcio Moreira e Chiara Das Dores Nascimento. "EFICÁCIA DA RADIAÇÃO UVC EM STAPHYLOCOCCUS AUREUS". In II Congresso Brasileiro de Biotecnologia On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2022. http://dx.doi.org/10.51189/conbiotec/05.

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Introdução: A luz UV cobre um espectro eletromagnético entre 200 a 400nm sendo subdividida em quatro regiões: UVA (315 a 400nm), UVB (280 a 315nm), UVC (200 a 280nm) e far UVC (207 a 222nm). A luz UVC é conhecida por apresentar um alto efeito germicida, inativando um amplo espectro de microorganismos, como fungos, vírus e bactérias, através da formação de dímeros de pirimidinas, que são danos nas moléculas de DNA ou RNA, que comprometem a replicação desses seres microscópicos. Estudos recentes mostram que, dentro de um ambiente hospitalar, até 5% das bactérias são do tipo Staphylococcus aureus, devido a sua presença na pele de grande parte das pessoas. Na maioria dos casos, a S. Aureus não causa perigo, no entanto quando atinge a corrente sanguínea pode causar pneumonia (infecção pulmonar) ou endocardite (infecção das válvulas cardíacas). A dose letal de UVC para inativar a S. Aureus já é conhecida, entretanto existem variações na literatura. Objetivos: O presente trabalho tem como objetivo determinar a dose letal, por irradiação direta, de uma lâmpada tubular UVC de 36 W, e comprimento de onda de pico em 254nm, em colônias de Staphylococcus aureus (ATCC 25923). Materiais e métodos: Para execução do experimento, foi efetuada uma diluição seriada (1:1000000), a partir da escala 0.5 Mcfarland. Então, um inóculo de 100 µL foi semeado em placas de ágar padrão as quais foram irradiadas com tempos variando entre 3 e 20 segundos. Imediatamente após, as colônias foram colocadas em uma estufa por 24h e 48h para crescimento. Resultados: Os resultados indicam que 10 segundos de irradiação direta, equivalentes a uma dose de 3,17mJ/cm2, reduzem cerca de 95% das colônias bacterianas. Conclusão: Os experimentos realizados comprovam que o uso da radiação UVC de 254nm é eficaz para inativação de microorganismos, no entanto, a dose encontrada encontra-se mais próxima do limite inferior encontrado na literatura, que varia entre os valores de 2,0 e 6,6 mJ/cm2.
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Rapporti di organizzazioni sul tema "Staphylococcus aureus"

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Sordillo, Lorraine, Don Wojchowski, Gary Perdew, Arthur Saran e Gabriel Leitner. Identification of Staphylococcus aureaus Virulence Factors Associated with Bovine Mastitis. United States Department of Agriculture, febbraio 2001. http://dx.doi.org/10.32747/2001.7574340.bard.

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Staphylococcus aureus is a major cause of mastitis in dairy cattle. The organism is able to adhere to and penetrate mammary epithelium, forming deep seated abscesses that result in chronic infections. This study was based on the observation that certain genotypes of S. aureus are isolated more frequently from field cases of bovine mastitis than others and the most prevalent genotypes of S. aureus have an increased ability to resist neutrophil phagocytosis and killing compared to the rare variants. It was hypothesized that these predominating genotypes differentially express virulence factors that allow them to overcome or suppress essential host defense mechanisms and successfully colonize mammary parenchyma. The overall objective of this study was to determine the mechanisms by which predominating S. aureus genotypes were able to resist mammary gland defense mechanisms. The following specific aims were accomplished to address the overall objectives of this project: 1. Analyze and compare cell surface and secreted protein profiles of common and rare S. aureus genotypes isolated from field cases of bovine mastitis. 2. Purify and sequence selectively synthesized proteins unique to the most prevalent genotypes of S. aureus . 3. Determine the in vitro effects of isolated proteins on essential host defense mechanisms. Results from each specific aim showed that these redominating genotypes differentially express factors that may allow them to overcome or suppress essential host defense mechanisms and successfully colonize mammary parenchyma. Using complementary approaches, both the US and Israeli teams identified differentially expressed S. aureus factors that were positively correlated with virulence as determined by the ability to modify host immune cell responses and increase disease pathogenesis. Several candidate virulence factors have ben identified at both the molecular (US team) and protein (Israeli team) levels. Components of the phosphotransferase system were shown to be differentially expressed in prevalent strains of S. aureus and to modify the growth potential of these strains in a milk microenvironment. Evidence provided by both the Israeli and US teams also demonstrated a potential role of Staphylococcal enterotoxins in the pathogenesis of mastitis. Certain enterotoxins were shown to directly affect neutrophil bactericidal activities which can profoundly affect the establishment of new intramammary infections. Other evidence suggests that S. aureus superantigens can suppress mammary defenses by enhancing lymphoid suppressor cell activity. Collectively, these data suggest that unique factors are associated with predominating S. aureus genotypes that can affect in vitro and in vivo virulence as related to the pathogenesis of bovine mastitis. The potential development of a subunit mastitis vaccine which incorporates only relevant antigenic determinants has not been investigated in depth. Experiments outlined in this proposal has identified putative virulence factors which contribute to the pathogenesis of S. aureus mastitis and which may be used to formulate an efficacious subunit mastitis vaccine. Results from these studies may lead to the development of new methods to prevent this costly disease, providing a viable alternative to less effective mastitis control procedures based on chemotherapy.
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Cheng, Xin, Juntong Zhou, Fan Yuan, Jingxin Ma, Shuilong Guo e Jianrong Su. Diagnostic Value of BHI-V4 for Heterogeneous and Vancomycin-Intermediate Staphylococcus aureus Isolates. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, dicembre 2023. http://dx.doi.org/10.37766/inplasy2023.12.0069.

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Spencer, Jessica, e Uzo Chukwuma. Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in the Department of Defense (DOD): Annual Summary 2013. Fort Belvoir, VA: Defense Technical Information Center, gennaio 2015. http://dx.doi.org/10.21236/ada612614.

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Timms, Leo L., e Phil Sears. Field Trial Evaluation of Extended Pirlimycin Therapy With or Without Vaccination for Staphylococcus Aureus Mastitis. Ames (Iowa): Iowa State University, gennaio 2004. http://dx.doi.org/10.31274/ans_air-180814-981.

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Ju, Mohan, Yueying Huang, Xiaofeng Xu, Yiyi Qian, Yingmin Bi, Shuang Liu, Xiangyu Li, Shuaiyue Dong, Jinyi Yuan e Dongfang Lin. Predictors of mortality in patients with Methicillin-resistant Staphylococcus aureus bloodstream infection: A meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, febbraio 2021. http://dx.doi.org/10.37766/inplasy2021.2.0082.

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Leas, Brian F., David A. Pegues e Nikhil K. Mull. Active Surveillance Culturing of Clostridioides difficile and Multi-Drug Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris. Agency for Healthcare Research and Quality (AHRQ), maggio 2024. http://dx.doi.org/10.23970/ahrqepc_mhs4culturing.

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Leitner, Gabriel, e Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, gennaio 2009. http://dx.doi.org/10.32747/2009.7709880.bard.

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Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post second immunization. rTRAP vaccine also elicited a cell-mediated immune response (memory CD4+ and CD8+ T cells), as determined by lymphocyte proliferation assays. The rTRAP vaccine was efficacious as at parturition, only 13.5% heifers in the immunized group were infected with Staphylococcus chromogenes as compared to 42.9% in the non immunized group. Additionally, when cows were immunized in mid-lactation, the difference between somatic cell count (SCC) in immunized and control animals was profound (45±7 vs. 470±194, respectively). At the same time, the difference in milk yield was also evident (48.3±1.4 vs. 44.3±0.9 l/day, respectively). Put together, these studies indicate the value of the rTRAP vaccine in preventing new udder infections by staphylococci, which significantly lead to lowered SCC and some increase in milk yield. TRAP is conserved among all strains and species and is constitutively expressed in any strain of S. aureus or CNS tested so far, including those isolated from cows. TRAP may thus serve as a universal anti-staphylococcus vaccine.
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Leitner, Gabriel, e Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, gennaio 2009. http://dx.doi.org/10.32747/2009.7695866.bard.

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Abstract (sommario):
Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post second immunization. rTRAP vaccine also elicited a cell-mediated immune response (memory CD4+ and CD8+ T cells), as determined by lymphocyte proliferation assays. The rTRAP vaccine was efficacious as at parturition, only 13.5% heifers in the immunized group were infected with Staphylococcus chromogenes as compared to 42.9% in the non immunized group. Additionally, when cows were immunized in mid-lactation, the difference between somatic cell count (SCC) in immunized and control animals was profound (45±7 vs. 470±194, respectively). At the same time, the difference in milk yield was also evident (48.3±1.4 vs. 44.3±0.9 l/day, respectively). Put together, these studies indicate the value of the rTRAP vaccine in preventing new udder infections by staphylococci, which significantly lead to lowered SCC and some increase in milk yield. TRAP is conserved among all strains and species and is constitutively expressed in any strain of S. aureus or CNS tested so far, including those isolated from cows. TRAP may thus serve as a universal anti-staphylococcus vaccine.
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Scheier, Thomas, Xiaomei Yao, John Eikelboom, Silvio Brugger, Dominik Mertz e Peter Schreiber. Efficacy of Staphylococcus aureus eradication at hospital admission on reduction of any infections within 90 days – a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, maggio 2024. http://dx.doi.org/10.37766/inplasy2024.5.0015.

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Oh, Ju Hyun, Aimee Martinez, Huaixuan Cao, Garrett George, Jared Cobb, Poonam Sharma, Lauren Fassero et al. Radio frequency heating of washable conductive textiles for bacteria and virus inactivation. Engineer Research and Development Center (U.S.), gennaio 2024. http://dx.doi.org/10.21079/11681/48060.

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Abstract (sommario):
The ongoing COVID-19 pandemic has increased the use of single-use medical fabrics such as surgical masks, respirators, and other personal protective equipment (PPE), which have faced worldwide supply chain shortages. Reusable PPE is desirable in light of such shortages; however, the use of reusable PPE is largely restricted by the difficulty of rapid sterilization. In this work, we demonstrate successful bacterial and viral inactivation through remote and rapid radio frequency (RF) heating of conductive textiles. The RF heating behavior of conductive polymer-coated fabrics was measured for several different fabrics and coating compositions. Next, to determine the robustness and repeatability of this heating response, we investigated the textile’s RF heating response after multiple detergent washes. Finally, we show a rapid reduction of bacteria and virus by RF heating our conductive fabric. 99.9% of methicillin-resistant Staphylococcus aureus (MRSA) was removed from our conductive fabrics after only 10 min of RF heating; human cytomegalovirus (HCMV) was completely sterilized after 5 min of RF heating. These results demonstrate that RF heating conductive polymercoated fabrics offer new opportunities for applications of conductive textiles in the medical and/or electronic fields.
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