Letteratura scientifica selezionata sul tema "SREBP"
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Articoli di riviste sul tema "SREBP"
Kober, Daniel L., Shimeng Xu, Shili Li, Bilkish Bajaj, Guosheng Liang, Daniel M. Rosenbaum e Arun Radhakrishnan. "Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis". Proceedings of the National Academy of Sciences 117, n. 45 (26 ottobre 2020): 28080–91. http://dx.doi.org/10.1073/pnas.2018578117.
Testo completoZhang, Lijun, Chunyan Li, Fang Wang, Shenghua Zhou, Mingjun Shangguan, Lina Xue, Bianying Zhang et al. "Treatment with PPARαAgonist Clofibrate Inhibits the Transcription and Activation of SREBPs and Reduces Triglyceride and Cholesterol Levels in Liver of Broiler Chickens". PPAR Research 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/347245.
Testo completoAn, Hyun-Jin, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyemin Gu, Hyun-Ju Kim, Jaechan Leem, Sung Won Youn e Kwan-Kyu Park. "Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia". International Journal of Molecular Sciences 21, n. 2 (15 gennaio 2020): 552. http://dx.doi.org/10.3390/ijms21020552.
Testo completoMahmud, Iqbal, Guimei Tian, Tarun Hutchison, Brandon Kim e Daiqing Liao. "Abstract LB138: DAXX interacts with sterol regulatory element-binding proteins (SREBPs) to promote oncogenic lipogenesis and tumorigenesis in triple-negative breast cancer". Cancer Research 82, n. 12_Supplement (15 giugno 2022): LB138. http://dx.doi.org/10.1158/1538-7445.am2022-lb138.
Testo completoWang, Hang, Feng Liu, Clarke F. Millette e Daniel L. Kilpatrick. "Expression of a Novel, Sterol-Insensitive Form of Sterol Regulatory Element Binding Protein 2 (SREBP2) in Male Germ Cells Suggests Important Cell- and Stage-Specific Functions for SREBP Targets during Spermatogenesis". Molecular and Cellular Biology 22, n. 24 (15 dicembre 2002): 8478–90. http://dx.doi.org/10.1128/mcb.22.24.8478-8490.2002.
Testo completoBien, Clara M., e Peter J. Espenshade. "Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis". Eukaryotic Cell 9, n. 3 (29 gennaio 2010): 352–59. http://dx.doi.org/10.1128/ec.00358-09.
Testo completoRIDGWAY, Neale D., e Thomas A. LAGACE. "Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms". Biochemical Journal 372, n. 3 (15 giugno 2003): 811–19. http://dx.doi.org/10.1042/bj20030252.
Testo completoZoumi, Aikaterini, Shrimati Datta, Lih-Huei L. Liaw, Cristen J. Wu, Gopi Manthripragada, Timothy F. Osborne e Vickie J. LaMorte. "Spatial Distribution and Function of Sterol Regulatory Element-Binding Protein 1a and 2 Homo- and Heterodimers by In Vivo Two-Photon Imaging and Spectroscopy Fluorescence Resonance Energy Transfer". Molecular and Cellular Biology 25, n. 8 (15 aprile 2005): 2946–56. http://dx.doi.org/10.1128/mcb.25.8.2946-2956.2005.
Testo completoAmemiya-Kudo, Michiyo, Hitoshi Shimano, Alyssa H. Hasty, Naoya Yahagi, Tomohiro Yoshikawa, Takashi Matsuzaka, Hiroaki Okazaki et al. "Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes". Journal of Lipid Research 43, n. 8 (agosto 2002): 1220–35. http://dx.doi.org/10.1194/jlr.m100417-jlr200.
Testo completoInoue, Noriyuki, Hitoshi Shimano, Masanori Nakakuki, Takashi Matsuzaka, Yoshimi Nakagawa, Takashi Yamamoto, Ryuichiro Sato et al. "Lipid Synthetic Transcription Factor SREBP-1a Activates p21WAF1/CIP1, a Universal Cyclin-Dependent Kinase Inhibitor". Molecular and Cellular Biology 25, n. 20 (15 ottobre 2005): 8938–47. http://dx.doi.org/10.1128/mcb.25.20.8938-8947.2005.
Testo completoTesi sul tema "SREBP"
Wu, Jiakai. "Primary rat hepatocyte isolation and culture regulates the SREBP/SREBP target gene profile". Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491482.
Testo completoLe, Lay Soazig. "Rôle des facteurs de transcription SREBP dans le métabolisme adipocytaire : implication de SREBP-1c dans la réponse à l'insuline et activation de SREBP-2 au cours de l'obésité". Paris 6, 2003. http://www.theses.fr/2003PA066188.
Testo completoIddon, Christopher R. "Investigation of the putative sterol pool that regulates SREBP cleavage". Thesis, University of Sheffield, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392930.
Testo completoYecies, Jessica. "SREBP: A Key Effector of mTORC1 Signaling in Metabolism and Cancer". Thesis, Harvard University, 2011. http://dissertations.umi.com/gsas.harvard:10023.
Testo completoRicoult, Stephane Jean Hermann. "Oncogenic Control and Metabolic Outputs of the Lipogenic Transcription Factor SREBP". Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493542.
Testo completoMedical Sciences
Eid, Walaa. "mTORC1 Activates SREBP-2 through Maintenance of Endosomal Cycling and Suppression of Autophagy". Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36473.
Testo completoDif, Nicolas. "Expression et régulation du facteur de transcription SREBP-1c humain : rôle de l'insuline". Lyon 1, 2006. http://www.theses.fr/2006LYO10216.
Testo completoSREBP-1c est un facteur de transcription de la famille SREBP (Sterol Regulatory Element Binding Protein. Plusieurs groupes ont mis en évidence le rôle de la protéine SREBP-1c dans la régulation de l’expression génique en réponse à l’insuline et aux variations nutritionnelles. L’étude de la régulation de SREBP-1c par l’insuline devrait donc nous permettre de mieux appréhender les mécanismes d'action de l'insuline. Au cours de ma thèse, j’ai tout d’abord étudié le rôle joué par le facteur SREBP-1c dans les principaux tissus insulino-sensibles sur le contrôle du métabolisme glucidique et lipidique, en étudiant la régulation de gènes clés de ces voies métaboliques, lors de variations de l'état nutritionnel. Ensuite, j’ai caractérisé le promoteur humain de SREBP-1c et déterminé les régions responsables de l’action de l’insuline. J’ai montré que les mécanismes impliqués étaient différents de ceux observés chez les rongeurs et que l’action transcriptionnelle de l’insuline implique essentiellement le facteur SREBP-1c lui-même
Liang, Wentao. "Myostatin promotes liver fat accumulation through activation of the mTOR-SREBP-1c pathway". Thesis, Boston University, 2012. https://hdl.handle.net/2144/12479.
Testo completoMyostatin is a cytokine primarily expressed in skeletal muscle and heart muscle and acts as a negative regulator for muscle development. Inhibition of myostatin by genetic and pharmacological approaches improves metabolic health, which has been generally considered as secondary to the hypermuscularity and insulin hyper-sensitivity. Although the receptor for myostatin is ubiquitously expressed, whether and how myostatin interacts with other metabolically important cell types remain largely unknown. In this work, we provide multiple lines of evidence that myostatin directly interacts with hepatocytes. Furthermore, we show for the first time that myostatin enhances insulin signaling in both cultured hepatocytes and in mouse liver. Mice injected with adena-associated virus encoding myostatin propeptide, an endogenous myostatin inhibitor, were partially protected from diet-induced liver fat accumulation and reduced lipogenic gene expression. Consistent with the in vivo findings, increased lipid accumulation was found in cells treated with myostatin peptide or transfected with myostatin construct. Myostatin promotes the lipogenic effect of insulin by enhancing nuclear translocation of SREBP-1c, the master lipogenic transcription factor and increases expression of its downstream target genes. This effect was found to be associated with myostatin-related mTOR activation. Blocking mTOR activation by rapamycin prevents myostatinassociated increase of nuclear SREBP-1 c and its downstream lipogenic enzymes. In summary, this work identified liver as a direct target of myostatin, providing the first evidence that myostatin has opposite impacts on insulin signaling in muscle cells and hepatocytes. Our data also provided a novel mechanism for the long-term metabolic protection afforded by anti-myostatin treatments demonstrated in this work as well as elsewhere.
Ma, Liying. "Regulatory factors of milk fat synthesis in dairy cows". Diss., Virginia Tech, 2012. http://hdl.handle.net/10919/29120.
Testo completoPh. D.
Asano, Lisa. "Vitamin D metabolite, 25-Hydroxyvitamin D, regulates lipid metabolism by inducing degradation of SREBP/SCAP". 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225512.
Testo completoLibri sul tema "SREBP"
Misbahuddin. Statin Pharmacogenetics in Metabolic Syndrome- The SREBP-SCAP Pathway. Germany: LAP LAMBERT Academic Publishing, 2012.
Cerca il testo completoSouthern Regional Education Board. Commission for Educational Quality, a cura di. A Progress report and recommendations on educational improvements in the SREB states: A report to the Southern Regional Education Board. Atlanta, Ga: SREB, 1987.
Cerca il testo completoGaines, Gale F. Educational Goals in Sreb States. Southern Regional Education Board, 1990.
Cerca il testo completoMarks, Joseph L. Sreb Fact Book on Higher Education (Sreb Fact Book on Higher Education 1998 99). Southern Regional Education Board, 1999.
Cerca il testo completoMarks, Joseph L. Sreb Fact Book on Higher Education 2000/2001 (Sreb Fact Book on Higher Education). Southern Regional Education Board, 2001.
Cerca il testo completoSreb Fact Book on Higher Education. Southern Regional Education Board, 1995.
Cerca il testo completoSreb Fact Book on Higher Education, 1990. Southern Regional Educ Board, 1990.
Cerca il testo completoMarks, Joseph L. Sreb Fact Book on Higher Education, 1990. Southern Regional Education Board, 1990.
Cerca il testo completoMarks, Joseph Lappin. Sreb Fact Book on Higher Education, 1992. Southern Regional Education Board, 1993.
Cerca il testo completoCrews, Alton Dr. Making Leadership Happen: The Sreb Model for Leadership. Southern Regional Education Board, 1996.
Cerca il testo completoCapitoli di libri sul tema "SREBP"
Ishida, Chiaki T., Wei Shao e Peter J. Espenshade. "Assaying Sterol-Regulated ER-to-Golgi Transport of SREBP Cleavage-Activating Protein Using Immunofluorescence Microscopy". In Methods in Molecular Biology, 755–64. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2639-9_45.
Testo completoInoue, Jun, e Ryuichiro Sato. "Transcriptional Regulation of the Genes for Human HMG CoA Synthase and Squalene Synthase by SREBP and NF-Y". In Lipoprotein Metabolism and Atherogenesis, 149–51. Tokyo: Springer Japan, 2000. http://dx.doi.org/10.1007/978-4-431-68424-4_32.
Testo completoShimano, Hitoshi, e Nobuhiro Yamada. "In vivo Functions of SREBPs". In Lipoprotein Metabolism and Atherogenesis, 137–41. Tokyo: Springer Japan, 2000. http://dx.doi.org/10.1007/978-4-431-68424-4_28.
Testo completoWolberg, Hans-Bernd. "SREP – Neues Prüfungskonzept der Bankenaufsicht". In Complexity Kills - Banken im Dickicht von Regulierung und verkrusteten Strukturen, 53–67. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-29287-4_5.
Testo completoBai, Yongxiu, e Songji Wang. "Framework of the SREB Initiative". In Spirit of the Silk Road, 1–42. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-4541-9_1.
Testo completoBai, Yongxiu, e Songji Wang. "Guarantee Mechanism for the SREB". In Spirit of the Silk Road, 217–67. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-4541-9_7.
Testo completoBarton, Larry L., e Guy D. Fauque. "Systems Contributing to the Energetics of SRBP". In Sulfate-Reducing Bacteria and Archaea, 245–93. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-96703-1_5.
Testo completoBoudra, Safia, Itheri Yahiaoui e Ali Behloul. "Statistical Radial Binary Patterns (SRBP) for Bark Texture Identification". In Advanced Concepts for Intelligent Vision Systems, 101–13. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-70353-4_9.
Testo completoSpeth, Michael. "Der neue SREP-Ansatz der internationalen Bankenaufsicht: Fortschritt oder Rückschritt?" In Die neue Welt der Banken, 33–51. Wiesbaden: Springer Fachmedien Wiesbaden, 2016. http://dx.doi.org/10.1007/978-3-658-14822-5_3.
Testo completoKotzka, Jörg, Wilhelm Krone e Dirk Müller-Wieland. "Sterol-regulatory element binding proteins (SREBPs): gene-regulatory target of statin action". In HMG-CoA Reductase Inhibitors, 35–54. Basel: Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8135-7_3.
Testo completoAtti di convegni sul tema "SREBP"
Ramachandran, Vimal, e S. Hani Najafi-shoushtari. "Srebp-2 Intronic Microrna 33a Post-translationally Controls Ldl Uptake". In Qatar Foundation Annual Research Conference Proceedings. Hamad bin Khalifa University Press (HBKU Press), 2014. http://dx.doi.org/10.5339/qfarc.2014.hbpp1091.
Testo completoplantier, laurent, Valérie Besnard e Jeffrey Whitsett. "Insig1 Regulates SREBP Mediated Lipogenesis In Alveolar Type 2 Cells". In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4953.
Testo completocheng, chunming, feng geng, xiang cheng, arnab chakravarti e deliang guo. "Abstract 1457: SCAP/SREBP-1 regulates lipid metabolism reprogramming in cancer cell". In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1457.
Testo completoHan, Chun-Chun, Ji-Wen Wang, Liang Li e Wei Wang. "The cDNA Segment Cloning and Bioinformatics Analysis of SREBP-2 Gene in Goose". In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2009). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5163582.
Testo completoLaMorte, Vickie J., Aikaterini Zoumi, Shrimati Datta, Cristen J. Wu e Timothy Osborne. "Utilization of two-photon FRET to monitor SREBP homodimer and heterodimer formation in living cells". In Biomedical Optics 2003, a cura di Ammasi Periasamy e Peter T. C. So. SPIE, 2003. http://dx.doi.org/10.1117/12.478034.
Testo completoLi, Xiangyan, Yi-Ting Chen, Leland W. K. Chung e Wen-Chin Huang. "Abstract 4728: Fatostatin, a novel SREBP inhibitor, suppresses cell growth and induces apoptosis in prostate cancer". In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4728.
Testo completoTorres-Ayuso, PEDRO, David Jones, Maria Tello-Lafoz, Antonia Avila-Flores e Isabel Merida. "Abstract 35: Diacylglycerol kinase zeta-mediated regulation of mTOR and SREBP-1 offers new opportunities for cancer management". In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-35.
Testo completoWang, Li, Chun-Chun Han, Ji-Wen Wang, Liang Li e Zhong-Xian Zhang. "Effect of Exogenous Cholesterol on Cholesterol Accumulation and mRNA Expression of SREBP-2 and HMGR in Goose Primary Hepatocytes". In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2009). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5162694.
Testo completoZhang, Xiaoxia, Yuan He, Yan Chen, Airong Zhang, Jing Sun e Tian Li. "Regulation of FFA metabolism and attenuation of lipid accumulation through AMPK/SREBP-1c signaling by the extract of Apium graveolens L. root". In ICBET 2022: 2022 12th International Conference on Biomedical Engineering and Technology. New York, NY, USA: ACM, 2022. http://dx.doi.org/10.1145/3535694.3535719.
Testo completoGuan, Min. "Abstract 2653: Nelfinavir induces apoptosis in hormone-resistant prostate cancer cells through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6". In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-2653.
Testo completoRapporti di organizzazioni sul tema "SREBP"
Moore, Gary. 1997 Summer Research Program (SRP), Summer Research Extension Program (SREP), Final Report, Volume 3. Rome Laboratory. Fort Belvoir, VA: Defense Technical Information Center, dicembre 1997. http://dx.doi.org/10.21236/ada386997.
Testo completoMoore, Gary. 1997 Summer Research Program (SRP), Summer Research Extension Program (SREP), Final Report, Volume 2. Phillips Laboratory. Fort Belvoir, VA: Defense Technical Information Center, dicembre 1997. http://dx.doi.org/10.21236/ada387081.
Testo completoMoore, Gary. 1997 Summer Research Program (SRP), Summer Research Extension Program (SREP), Final Report, Volume 1. Program Management and Armstrong Laboratory. Fort Belvoir, VA: Defense Technical Information Center, dicembre 1997. http://dx.doi.org/10.21236/ada387080.
Testo completoMoore, Gary. 1997 Summer Research Program (SRP), Summer Research Extension Program (SREP), Final Report, Volume 5. Arnold Engineering Center, Air Logistics Centers, United States Air Force Academy, Wilford Hall Medical Center. Fort Belvoir, VA: Defense Technical Information Center, dicembre 1997. http://dx.doi.org/10.21236/ada387014.
Testo completo