Letteratura scientifica selezionata sul tema "Spectroscopie Raman Exaltée par effet de Surface (SERS)"
Cita una fonte nei formati APA, MLA, Chicago, Harvard e in molti altri stili
Indice
Consulta la lista di attuali articoli, libri, tesi, atti di convegni e altre fonti scientifiche attinenti al tema "Spectroscopie Raman Exaltée par effet de Surface (SERS)".
Accanto a ogni fonte nell'elenco di riferimenti c'è un pulsante "Aggiungi alla bibliografia". Premilo e genereremo automaticamente la citazione bibliografica dell'opera scelta nello stile citazionale di cui hai bisogno: APA, MLA, Harvard, Chicago, Vancouver ecc.
Puoi anche scaricare il testo completo della pubblicazione scientifica nel formato .pdf e leggere online l'abstract (il sommario) dell'opera se è presente nei metadati.
Tesi sul tema "Spectroscopie Raman Exaltée par effet de Surface (SERS)"
Reymond-Laruinaz, Sébastien. "Biomolécules et systèmes nanostructurés : caractérisation par spectrométrie Raman exaltée de surface (SERS)". Thesis, Dijon, 2014. http://www.theses.fr/2014DIJOS023/document.
Testo completoThis work addressed the study of several kinds of nanostructured systems, biomolecules and inorganic thin films, mainly by Surface Enhanced Raman Spectroscopy (SERS). The aim was to investigate the structure and the chemical bonds. Transmission electron microscopy (TEM) was also used to complete the structural characterization of the different samples.Firstly, the study was conducted on molecules of biological interest. The aim was to study the interaction between silver nanoparticles and proteins. With this aim, silver nanoparticles bioconjugated with different proteins (hemoglobin, cytochrome C, BSA and lysozim) were synthesized. SERS results allowed concluding that proteins are chemisorbed on the silver nanoparticules surface. SERS was also used in the low frequency range to characterize the structure of thin deposits of caffeine, a molecule of pharmaceutical interest.Raman spectroscopy and SERS were also used to study nanostructured TiO2:Au thin films. The first stages of the growth of gold nanoparticles in Au doped TiO2 thin films under annealing treatments were studied by low frequency Raman spectroscopy and TEM. Finally, it was shown that SERS effect can be used for the characterization of ultra-thin TiO2 films. With this aim, ultra-thin TiO2 films were deposited by Atomic Layer Deposition on Si substrates functionalized with gold nanoparticles and studied by SERS
Siskova, Karolina. "Elaboration de nouvelles nanostructures d'Argent, obtenues par abblation laser, pour caractériser des macro- et biomolécules par spectroscopie Raman exaltée par effet de surface". Paris 6, 2006. http://www.theses.fr/2006PA066509.
Testo completoTouzalin, Thomas. "Tip-enhanced Raman spectroscopy on electrochemical systems". Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS364.
Testo completoThe in situ investigation of electrochemical interfaces structures at the nanoscale is a key element in the understanding of charge and electron transfer mechanisms e.g. in the fields of energy storage or electrocatalysis. This thesis introduces the implementation of tip-enhanced Raman spectroscopy (TERS) in liquid and in electrochemical conditions enabling the nanoscale analysis of electrified solid/liquid interfaces through the strong and local electric field enhancement at gold or silver scanning tunneling microscopy (STM) probes. The ability of TERS to image inhomogeneities in the coverage density of a self-assembled monolayer (SAM) through a layer of organic solvent on gold was demonstrated. A TERS-inspired analytical tool was also developed, based on a TERS tip used simultaneously as a single-hot spot surface-enhanced Raman spectroscopy (SERS) platform and as a microelectrode (EC tip SERS). The reduction of an electroactive SAM could then be monitored by electrochemical and in situ SERS measurements. In situ electrochemical STM-TERS was also evidenced through the imaging of local variations of the electric field enhancement on peculiar sites of a gold electrode with a lateral resolution lower than 8 nm. Finally TERS also demonstrated to be efficient in investigating the structure of organic layers grafted either by electrochemical reduction or spontaneously. This work is therefore a major advance for the analysis of functionalized surfaces
Hachin, Axelle. "Développement d'une plateforme de détection SERS à partir de monocouches auto-assemblées". Electronic Thesis or Diss., Bordeaux, 2023. http://www.theses.fr/2023BORD0481.
Testo completoBiosensors are real-time detection systems for biological species widely used in diagnostics. Surface Enhanced Raman Spectroscopy (SERS), with its specific and sensitive identification capability, is a good way of detecting biomolecules (aptamers, peptides, etc.) using suitable surfaces (such as metal nanostructures, nanoparticles, etc.). With a view to developing a SERS biosensor, a detection platform based on self-assembled monolayers (SAMs) functionalized with spherical or cylindrical gold nanoparticles was designed. The thesis work consisted in producing SAMs based on organosilane bearing an azide or amine terminal function. The SAMs were then modified by reaction with linkers, either by peptide coupling or click chemistry, to provide thiol or cyclooctyne end functions. These modifications are characterized by various techniques such as PM-IRRAS, AFM, XPS or ToF-SIMS. Gold nanoparticles have been successfully immobilized by two different routes: on azide-terminated SAMs by click chemistry and on thiol-terminated SAMs by ligand exchange. Promising initial results have been obtained demonstrating SERS detection of the bioreceptor immobilized on the nanoparticles
Aybeke, Ece Neslihan. "Study of the dynamics of biomolecules by high speed atomic force microscopy and surface enhanced Raman spectroscopy". Thesis, Dijon, 2015. http://www.theses.fr/2015DIJOS023/document.
Testo completoThis thesis focuses on the coupling of High–Speed Atomic Force Microscopy (HS-AFM) and Surface Enhanced Raman Spectroscopy (SERS) for biomolecule analysis. We have designed a fabrication protocol to manufacture “SERS-active” substrates. The efficacy of gold, silver and gold-silver bimetallic crystalline nanoparticle substrates were evaluated. We have investigated the impact of optical and morphological features of the substrates on Raman signal intensity by analyzing well-known samples such as bipyridine ethylene and methylene blue molecules. We took an interest in three distinct biological problematics with HS-AFM and SERS analyses. First, we have detected the chemical signature of cytochrome b5 protein. This study was followed by the investigation of conformational changes of small heat shock leuconostoc oenos Lo 18 protein in function of pH level and concentrations. The last application consists to the analyse a membrane and a virus interaction. In order to realize simultaneous Raman/AFM analysis, we have adapted our fabrication protocol to cover the surface of commercial AFM probes by crystalline gold nanoparticles. Tip – Enhanced Raman Spectroscopy (TERS) studies were performed on molybdenum disulfide to evaluate the quality of TERS probes. In the last part of this work, we have designed a new setup to combine Ando’s HS-AFM setup with Raman spectroscopy. We present the modifications that have been carried out and the challenges that we have encountered
Andrei, Cassiana. "Détection directe et sélective de bactéries par imagerie Raman exaltée de surface". Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLX065.
Testo completoRapid detection of bacterial pathogens is an important challenge nowadays in multiple fields like in food industry, health and military biodefense. Biosensors are promising candidates for replacing time consuming and expensive classical tools. In this work, we developed biosensors based on hydrogenated amorphous silicon layer for the covalent grafting of probes (antibodies or sugars) interacting specifically with bacteria, and noble metal nanoparticles for spectroscopic identification of trapped bacteria by surface enhanced Raman spectroscopy (SERS). In a first approach, the production of stable and cost-effective SERS-active substrates based on metallic thin films was proposed for the study of various bacteria. Different SERS fingerprints of three different strains of the same bacteria were obtained allowing their discrimination, result confirmed by principal component analysis (PCA). In a second approach, SERS study of bacteria was performed using nanoparticles colloids, positively charged gold nanorods showing the best reproducibility. In parallel, the optimization of probes grafting on the amorphous silicon surface and of the blocking step for minimization of non-specific adhesion of bacteria were performed. Finally, tests with the entire architecture of the biosensor were performed and by using a fluidic cell the attachment of bacteria was monitored in situ. After contact with gold nanorods the specific identification of bacteria by SERS was possible. Using this strategy limits of detection up to 10 cfu/mL were achieved in a total time of detection of 3 h
Chapus, Lionel. "Organisation de nanoparticules de métaux nobles : application à la spectroscopie Raman exaltée de surface et à l'électrochimie". Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066258/document.
Testo completoMetallic nanoparticles (NPs) have been subjected to a growing interest these last years in various domains such as healthcare, environment or electronics. In this thesis, we were particularly interested in the application of NPs mono or bimetallic made of noble metals in plasmonic domain. In this way, we synthesized by organometallic route, monometallic NPs of gold, silver and copper with a diameter ranging from 5 to 11 nm and characterized by a narrow polydispersity. After deposition on a solid substrate, they organized themselves spontaneously in 3D forming individual supercrystals. We studied the optical properties of these supercrystals, by measuring their absorbance spectra in function of their thicknesses and the nature of the NPs. Then, we showed that these supercrystals can be used as SERS substrates. The mean diameter of the NPs is way smaller than the ones reported in the literature. These substrates display a uniform and reproductible signal from a supercrystal to another. The Raman spectra of coating agent (alkanethiols or alkylamines) have been collected and enhancement factor ranging from 103 to 104 have been calculated. After verification by electroreflectance of NPs stability over a wide potential range, we coupled SERS with electrochemistry by using a monolayer of organized gold NPs as an electrode. Coverage rates for two different molecules adsorbed on the NPs have been calculated. Moreover, we could follow and confirm the species formation during the oxydoreduction reactions of the adsorbed molecules by SERS. Finally, we synthesized core-shell NPs Au@Ag, Ag@Au and alloy NPs Cu-Au by using gold, silver and copper NPs as seeds. Their structures and chemical compositions have been studied. Their optical spectra have been measured by UV-Visible spectroscopy and simulated by DDA (Discrete Dipole Approximation). They confirmed the core-shell and alloy structures. By low frequency Raman spectroscopy, for the Au@Ag NPs, we showed a coupling between the core and the shell in accordance with the core-shell model developed in the literature. For the Cu-Au NPs, low-frequency Raman signal is in agreement with the formation of an alloy
Le, Nader Victor. "Approche expérimentale et théorique de la diffusion Raman exaltée : résonance des plasmons de surface et effet de pointe". Phd thesis, Université de Nantes, 2010. http://tel.archives-ouvertes.fr/tel-00559365.
Testo completoKaya, Zeynep. "Controlled and localized synthesis of molecularly imprinted polymers for chemical sensors". Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2220.
Testo completoMolecularly imprinted polymers (MIPs), also referred to as plastic antibodies, are synthetic biomimetic receptors that are able to bind target molecules with similar affinity and specificity as natural receptors such as enzymes or antibodies. Indeed, MIPs are used as synthetic recognition elements in biosensors and biochips for the detection of small analytes and proteins. The molecular imprinting technique is based on the formation of specific recognition cavities in polymer matrices by a templating process at the molecular level. For sensor and biochip development, fast binding kinetics of the MIP for a rapid sensor response, the integration of the polymers with transducers, and a high sensitivity of detection are among the main challenges. In this thesis, the above issues are addressed by developing MIP/gold nanocomposites by grafting MIPs on surfaces, using dedicated techniques like atom transfer radical polymerization (ATRP) which is a versatile controlled radical polymerization (CRP) technique. Theses ophisticated CRP techniques, are able to greatly improve the polymeric materials. The use of ATRP in the MIP field has been limited so far due to its inherent incompatibility with acidic monomers like methacrylic acid (MAA), which is by far the most widely used functional monomer. Herein, a new method is described for the MIP synthesis through photo-initiated ATRP using fac-[Ir(ppy)3] as ATRP catalyst. The synthesis is possible at room temperature and is compatible with acidic monomers. This study considerably widens the range of functional monomers and thus molecular templates that can be used when MIPs are synthesized by ATRP. The proposed method was used for fabrication of hierarchically organised nanocomposites based on MIPs and nanostructured metal surfaces containing nanoholes or nanoislands, exhibiting plasmonic effects for signal amplification. The fabrication of nanometer scale MIP coatings localized on gold surface was demonstrated. Optical transduction methods, namely Localized Surface Plasmon Resonance (LSPR) and Surface Enhanced Raman Spectroscopy (SERS) were exploited and shown that they hold great promise for enhancing the limit of detection in sensing of biologically relevant analytes including proteins and the drug propranolol
Tchinda, Sonhapi Arielle. "Analyse Conformationnelle des Protéines en Réponse à l'Environnement (pH et Température) par Spectroscopie Raman Exaltée en Surface (SERS)". Electronic Thesis or Diss., Bourgogne Franche-Comté, 2023. http://www.theses.fr/2023UBFCK080.
Testo completoThe thesis presented offers an in-depth exploration of protein structures and behaviors, with a particular focus on their interactions with colloidal gold nanoparticles. To analyze protein modifications in response to variations in pH and temperature, Arielle utilizes Surface-Enhanced Raman Spectroscopy (SERS) techniques as well as microfluidics.The analysis of protein secondary structure, using bovine serum albumin (BSA) as a model, reveals close links with the overall protein conformation. Changes in pH and temperature result in significant conformational alterations, visible in the analysis of amides I, II, and III. Furthermore, the study is not limited to well-structured proteins but also encompasses intrinsically disordered proteins (IDPs), which adopt flexible conformations in response to their environment, thus expanding our understanding of the structural complexity of proteins.Exploring protein-nanoparticle interactions serves as a basis for understanding how this structural diversity translates into a variety of biological functions. Arielle employs an innovative approach based on Markov chains to analyze protein disorder, providing a comprehensive view of protein flexibility and plasticity, with successful applications to BSA and alpha-synuclein.Finally, the thesis underscores the importance of understanding conformational dynamics at the single-protein level in biological processes, with potential implications for medical and biotechnological advancements
Capitoli di libri sul tema "Spectroscopie Raman Exaltée par effet de Surface (SERS)"
BARDEAU, Jean-francois, Bernard HUMBERT, Angélina D'ORLANDO e Guy LOUARN. "Spectroscopie vibrationnelle exaltée : Raman résonnant et SERS". In Spectroscopies vibrationnelles, 221–46. Editions des archives contemporaines, 2020. http://dx.doi.org/10.17184/eac.4202.
Testo completo