Articoli di riviste sul tema "RNA-Targeted small molecules"
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Costales, Matthew G., Haruo Aikawa, Yue Li, Jessica L. Childs-Disney, Daniel Abegg, Dominic G. Hoch, Sai Pradeep Velagapudi et al. "Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer". Proceedings of the National Academy of Sciences 117, n. 5 (21 gennaio 2020): 2406–11. http://dx.doi.org/10.1073/pnas.1914286117.
Testo completoNagano, Konami, Takashi Kamimura e Gota Kawai. "Interaction between a fluoroquinolone derivative and RNAs with a single bulge". Journal of Biochemistry 171, n. 2 (16 novembre 2021): 239–44. http://dx.doi.org/10.1093/jb/mvab124.
Testo completoSun, Saisai, Jianyi Yang e Zhaolei Zhang. "RNALigands: a database and web server for RNA–ligand interactions". RNA 28, n. 2 (3 novembre 2021): 115–22. http://dx.doi.org/10.1261/rna.078889.121.
Testo completoTadesse, Kisanet, e Raphael I. Benhamou. "Targeting MicroRNAs with Small Molecules". Non-Coding RNA 10, n. 2 (14 marzo 2024): 17. http://dx.doi.org/10.3390/ncrna10020017.
Testo completoWu, Liping, Jing Pan, Vala Thoroddsen, Deborah R. Wysong, Ronald K. Blackman, Christine E. Bulawa, Alexandra E. Gould et al. "Novel Small-Molecule Inhibitors of RNA Polymerase III". Eukaryotic Cell 2, n. 2 (aprile 2003): 256–64. http://dx.doi.org/10.1128/ec.2.2.256-264.2003.
Testo completoAngelbello, Alicia J., Suzanne G. Rzuczek, Kendra K. Mckee, Jonathan L. Chen, Hailey Olafson, Michael D. Cameron, Walter N. Moss, Eric T. Wang e Matthew D. Disney. "Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model". Proceedings of the National Academy of Sciences 116, n. 16 (29 marzo 2019): 7799–804. http://dx.doi.org/10.1073/pnas.1901484116.
Testo completoAlagia, Adele, Jana Tereňová, Ruth F. Ketley, Arianna Di Fazio, Irina Chelysheva e Monika Gullerova. "Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing". Life Science Alliance 6, n. 6 (10 aprile 2023): e202302054. http://dx.doi.org/10.26508/lsa.202302054.
Testo completoFrancois-Moutal, Liberty, David Donald Scott e May Khanna. "Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape". RSC Chemical Biology 2, n. 4 (2021): 1158–66. http://dx.doi.org/10.1039/d1cb00110h.
Testo completoSmola, Matthew J., Krista Marran, Sarah E. Thompson, Brittani Patterson, Roheeth K. Pavana, Caleb Sutherland, Jessica A. Sorrentino e Katherine D. Warner. "Abstract 680: Leveraging an RNA-targeting platform for the discovery of cell-active c-MYC mRNA-binding small molecules". Cancer Research 84, n. 6_Supplement (22 marzo 2024): 680. http://dx.doi.org/10.1158/1538-7445.am2024-680.
Testo completoMirón-Barroso, Sofía, Joana S. Correia, Adam E. Frampton, Mark P. Lythgoe, James Clark, Laura Tookman, Silvia Ottaviani et al. "Polymeric Carriers for Delivery of RNA Cancer Therapeutics". Non-Coding RNA 8, n. 4 (2 agosto 2022): 58. http://dx.doi.org/10.3390/ncrna8040058.
Testo completoMartín-Villamil, María, Isaías Sanmartín, Ángela Moreno e José Gallego. "Pharmacophore-Based Discovery of Viral RNA Conformational Modulators". Pharmaceuticals 15, n. 6 (14 giugno 2022): 748. http://dx.doi.org/10.3390/ph15060748.
Testo completoHardigan, Andrew A., Brian S. Roberts, Dianna E. Moore, Ryne C. Ramaker, Angela L. Jones e Richard M. Myers. "CRISPR/Cas9-targeted removal of unwanted sequences from small-RNA sequencing libraries". Nucleic Acids Research 47, n. 14 (5 giugno 2019): e84-e84. http://dx.doi.org/10.1093/nar/gkz425.
Testo completoTran, Anh Thi-Phuong, Duc Huy Vo, Audrey Di Giorgio e Maria Duca. "ID: 1083 Targeting the production of oncogenic miRNAs using synthetic small molecules". Biomedical Research and Therapy 4, S (5 settembre 2017): 170. http://dx.doi.org/10.15419/bmrat.v4is.357.
Testo completoPalazzotti, Deborah, Martina Sguilla, Giuseppe Manfroni, Violetta Cecchetti, Andrea Astolfi e Maria Letizia Barreca. "Small Molecule Drugs Targeting Viral Polymerases". Pharmaceuticals 17, n. 5 (20 maggio 2024): 661. http://dx.doi.org/10.3390/ph17050661.
Testo completoLiu, Yuan, Mads B. Larsen, Bo Lin, Jason R. Kennerdell, Irene Alfaras, Daniel P. Camarco, Ferhan Tuncer, Toren Finkel e Bill B. Chen. "Abstract 1805: Identification of a small molecule that induces targeted protein degradation of ADAR1". Cancer Research 83, n. 7_Supplement (4 aprile 2023): 1805. http://dx.doi.org/10.1158/1538-7445.am2023-1805.
Testo completoAkbar, Sehrish, Yao Wei e Mu-Qing Zhang. "RNA Interference: Promising Approach to Combat Plant Viruses". International Journal of Molecular Sciences 23, n. 10 (10 maggio 2022): 5312. http://dx.doi.org/10.3390/ijms23105312.
Testo completoCotten, M., G. Schaffner e M. L. Birnstiel. "Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro". Molecular and Cellular Biology 9, n. 10 (ottobre 1989): 4479–87. http://dx.doi.org/10.1128/mcb.9.10.4479-4487.1989.
Testo completoCotten, M., G. Schaffner e M. L. Birnstiel. "Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro." Molecular and Cellular Biology 9, n. 10 (ottobre 1989): 4479–87. http://dx.doi.org/10.1128/mcb.9.10.4479.
Testo completoThaper, Daksh L., Ravi Munuganti, Shaghayegh Nouruzi, Sahil Kumar, Soojin Kim, Sepideh Vahid, Olena Sivak et al. "First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer." Journal of Clinical Oncology 37, n. 7_suppl (1 marzo 2019): 260. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.260.
Testo completoAla, Ugo. "Competing Endogenous RNAs, Non-Coding RNAs and Diseases: An Intertwined Story". Cells 9, n. 7 (28 giugno 2020): 1574. http://dx.doi.org/10.3390/cells9071574.
Testo completoRimoldi, O. J., B. Raghu, M. K. Nag e G. L. Eliceiri. "Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA". Molecular and Cellular Biology 13, n. 7 (luglio 1993): 4382–90. http://dx.doi.org/10.1128/mcb.13.7.4382-4390.1993.
Testo completoRimoldi, O. J., B. Raghu, M. K. Nag e G. L. Eliceiri. "Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA." Molecular and Cellular Biology 13, n. 7 (luglio 1993): 4382–90. http://dx.doi.org/10.1128/mcb.13.7.4382.
Testo completoFei, Yue, Tünde Nyikó e Attila Molnar. "Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs". Nucleic Acids Research 49, n. 4 (1 febbraio 2021): 1900–1913. http://dx.doi.org/10.1093/nar/gkab023.
Testo completoTao, Wei, Arif Yurdagul, Na Kong, Wenliang Li, Xiaobo Wang, Amanda C. Doran, Chan Feng et al. "siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice". Science Translational Medicine 12, n. 553 (22 luglio 2020): eaay1063. http://dx.doi.org/10.1126/scitranslmed.aay1063.
Testo completoRojas-Cruz, Alexis Felipe, e Clara Isabel Bermúdez-Santana. "Computational Prediction of RNA–RNA Interactions between Small RNA Tracks from Betacoronavirus Nonstructural Protein 3 and Neurotrophin Genes during Infection of an Epithelial Lung Cancer Cell Line: Potential Role of Novel Small Regulatory RNA". Viruses 15, n. 8 (28 luglio 2023): 1647. http://dx.doi.org/10.3390/v15081647.
Testo completoAlonso-Valenteen, Felix, Sayuri Pacheco, Dustin Srinivas, Altan Rentsendorj, David Chu, Jay Lubow, Jessica Sims et al. "HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo". Nucleic Acids Research 47, n. 21 (16 ottobre 2019): 11020–43. http://dx.doi.org/10.1093/nar/gkz900.
Testo completoServan de Almeida, Renata, Djénéba Keita, Geneviève Libeau e Emmanuel Albina. "Control of ruminant morbillivirus replication by small interfering RNA". Journal of General Virology 88, n. 8 (1 agosto 2007): 2307–11. http://dx.doi.org/10.1099/vir.0.82981-0.
Testo completoGoldberg, Zelanna, Christian Maine, Gabrielle P. Dailey, Christine Domingo, Gaelle Picarda, Hunter Little, Annie Chou et al. "Abstract 6403: A self-replicating RNA precision medicine approach to overcoming resistance to endocrine therapy in ER+BC". Cancer Research 83, n. 7_Supplement (4 aprile 2023): 6403. http://dx.doi.org/10.1158/1538-7445.am2023-6403.
Testo completoLi, Quan, Yanan Wang, Zhihui Sun, Haiyang Li e Huan Liu. "The Biosynthesis Process of Small RNA and Its Pivotal Roles in Plant Development". International Journal of Molecular Sciences 25, n. 14 (12 luglio 2024): 7680. http://dx.doi.org/10.3390/ijms25147680.
Testo completoAshander, Liam M., Binoy Appukuttan, Yuefang Ma, Dione Gardner-Stephen e Justine R. Smith. "Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study". Mediators of Inflammation 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/7945848.
Testo completoHassanzadeh, Leila, Suxiang Chen e Rakesh Veedu. "Radiolabeling of Nucleic Acid Aptamers for Highly Sensitive Disease-Specific Molecular Imaging". Pharmaceuticals 11, n. 4 (15 ottobre 2018): 106. http://dx.doi.org/10.3390/ph11040106.
Testo completoLavender, Helen, Kevin Brady, Frances Burden, Oona Delpuech-Adams, Hubert Denise, Amy Palmer, Hannah Perkins et al. "In VitroCharacterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy". Antimicrobial Agents and Chemotherapy 56, n. 3 (27 dicembre 2011): 1364–75. http://dx.doi.org/10.1128/aac.05357-11.
Testo completoColl-SanMartin, Laia, Veronica Davalos, David Piñeyro, Margalida Rosselló-Tortella, Alberto Bueno-Costa, Fernando Setien, Alberto Villanueva et al. "Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer". Cancers 13, n. 8 (14 aprile 2021): 1869. http://dx.doi.org/10.3390/cancers13081869.
Testo completoHagiwara, Shinji, Aaron McClelland e Phillip Kantharidis. "MicroRNA in Diabetic Nephropathy: Renin Angiotensin, AGE/RAGE, and Oxidative Stress Pathway". Journal of Diabetes Research 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/173783.
Testo completoJoshi, Mansi, Pranay Dey e Abhijit De. "Recent advancements in targeted protein knockdown technologies—emerging paradigms for targeted therapy". Exploration of Targeted Anti-tumor Therapy 4, n. 6 (26 dicembre 2023): 1227–48. http://dx.doi.org/10.37349/etat.2023.00194.
Testo completoTidwell, Elizabeth D., Ingrid R. Kilde, Suada Leskaj e Markos Koutmos. "Fluorescent Ligand Equilibrium Displacement: A High-Throughput Method for Identification of FMN Riboswitch-Binding Small Molecules". International Journal of Molecular Sciences 25, n. 2 (6 gennaio 2024): 735. http://dx.doi.org/10.3390/ijms25020735.
Testo completoKalynych, Sergei, Lenka Pálková e Pavel Plevka. "The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid". Journal of Virology 90, n. 3 (18 novembre 2015): 1377–86. http://dx.doi.org/10.1128/jvi.02346-15.
Testo completoShen, Linyuan, Zhendong Tan, Mailin Gan, Qiang Li, Lei Chen, Lili Niu, Dongmei Jiang et al. "tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis". Biomolecules 9, n. 7 (11 luglio 2019): 274. http://dx.doi.org/10.3390/biom9070274.
Testo completoSimba-Lahuasi, Alvaro, Ángel Cantero-Camacho, Romel Rosales, Briana Lynn McGovern, M. Luis Rodríguez, Vicente Marchán, Kris M. White, Adolfo García-Sastre e José Gallego. "SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules". Pharmaceuticals 15, n. 12 (22 novembre 2022): 1448. http://dx.doi.org/10.3390/ph15121448.
Testo completoHarrington, Lucas B., David Burstein, Janice S. Chen, David Paez-Espino, Enbo Ma, Isaac P. Witte, Joshua C. Cofsky, Nikos C. Kyrpides, Jillian F. Banfield e Jennifer A. Doudna. "Programmed DNA destruction by miniature CRISPR-Cas14 enzymes". Science 362, n. 6416 (18 ottobre 2018): 839–42. http://dx.doi.org/10.1126/science.aav4294.
Testo completoMourenza, Álvaro, Blanca Lorente-Torres, Elena Durante, Jesús Llano-Verdeja, Jesús F. Aparicio, Arsenio Fernández-López, José A. Gil, Luis M. Mateos e Michal Letek. "Understanding microRNAs in the Context of Infection to Find New Treatments against Human Bacterial Pathogens". Antibiotics 11, n. 3 (8 marzo 2022): 356. http://dx.doi.org/10.3390/antibiotics11030356.
Testo completoCrisci, Amitrano, Saggese, Muto, Sarno, Mele, Vitale, Ronga, Berretta e Di Francia. "Overview of Current Targeted Anti-Cancer Drugs for Therapy in Onco-Hematology". Medicina 55, n. 8 (28 luglio 2019): 414. http://dx.doi.org/10.3390/medicina55080414.
Testo completoCiccone, Giuseppe, Maria Luigia Ibba, Gabriele Coppola, Silvia Catuogno e Carla Lucia Esposito. "The Small RNA Landscape in NSCLC: Current Therapeutic Applications and Progresses". International Journal of Molecular Sciences 24, n. 7 (24 marzo 2023): 6121. http://dx.doi.org/10.3390/ijms24076121.
Testo completoMorais, Pedro, Rui Zhang e Yi-Tao Yu. "Therapeutic Nonsense Suppression Modalities: From Small Molecules to Nucleic Acid-Based Approaches". Biomedicines 12, n. 6 (10 giugno 2024): 1284. http://dx.doi.org/10.3390/biomedicines12061284.
Testo completoXiao, Fei, Chenglong Wang, Jianping Peng, Xing Zhou, Ding Ma, Yu Wang, Yanpeng Li, Xiaodong Chen e Chuandong Wang. "Changes in Small Noncoding RNA Expression during Chondrocyte Senescence". CARTILAGE 13, n. 3 (luglio 2022): 194760352211181. http://dx.doi.org/10.1177/19476035221118165.
Testo completoKakumani, Pavan Kumar, Louis-Mathieu Harvey, François Houle, Tanit Guitart, Fátima Gebauer e Martin J. Simard. "CSDE1 controls gene expression through the miRNA-mediated decay machinery". Life Science Alliance 3, n. 4 (11 marzo 2020): e201900632. http://dx.doi.org/10.26508/lsa.201900632.
Testo completoCunningham, Tyler A., Derek Essegian, Stephan Schürer e Jonathan H. Schatz. "Identification of Tractable Drug-like eIF4Al Inhibitors with Potent Anti-Tumor Activity". Blood 134, Supplement_1 (13 novembre 2019): 5760. http://dx.doi.org/10.1182/blood-2019-130494.
Testo completoAughton, Karen, Helen Kalirai e Sarah E. Coupland. "MicroRNAs and Uveal Melanoma: Understanding the Diverse Role of These Small Molecular Regulators". International Journal of Molecular Sciences 21, n. 16 (6 agosto 2020): 5648. http://dx.doi.org/10.3390/ijms21165648.
Testo completoChauhan, Waseem, Sudharshan SJ, Sweta Kafle e Rahima Zennadi. "SnoRNAs: Exploring Their Implication in Human Diseases". International Journal of Molecular Sciences 25, n. 13 (29 giugno 2024): 7202. http://dx.doi.org/10.3390/ijms25137202.
Testo completoUyeno, Yutaka, Yuji Sekiguchi, Akiko Sunaga, Hiroki Yoshida e Yoichi Kamagata. "Sequence-Specific Cleavage of Small-Subunit (SSU) rRNA with Oligonucleotides and RNase H: a Rapid and Simple Approach to SSU rRNA-Based Quantitative Detection of Microorganisms". Applied and Environmental Microbiology 70, n. 6 (giugno 2004): 3650–63. http://dx.doi.org/10.1128/aem.70.6.3650-3663.2004.
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