Bibliografie tematiche / Regeneration

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Letteratura scientifica selezionata sul tema "Regeneration"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 28 settembre 2024

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Articoli di riviste sul tema "Regeneration"

Calvin, James M., e Marvin K. Nakayama. "SIMULATION OF PROCESSES WITH MULTIPLE REGENERATION SEQUENCES". Probability in the Engineering and Informational Sciences 14, n. 2 (aprile 2000): 179–201. http://dx.doi.org/10.1017/s0269964800142056.

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The classical regenerative method of simulation output analysis exploits the regenerative structure of a stochastic process to break up a path into independent and identically distributed cycles based on a single sequence of regeneration times. If a process is regenerative with respect to more than one sequence of regeneration times, the classical regenerative method does not exploit the additional structure, and the variance of the resulting estimator for certain performance measures (e.g., the time-average variance constant) can vary greatly, depending on the particular regeneration sequence chosen. In a previous article, we introduced an efficiency-improvement technique for regenerative simulation of processes having two sequences of regeneration times based on permuting regenerative cycles associated with the second sequence of regeneration points. In this article, we show how to exploit more than two regeneration sequences. In particular, for birth–death Markov chains, the regenerations associated with hitting times to each state can all be exploited. We present empirical results that show significant variance reductions in some cases, and the results seem to indicate that the permuted estimator for the time-average variance constant can have a variance that is independent of the primary regeneration sequence used to run the simulation.

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Li, Yan, Lungen Lu e Xiaobo Cai. "Liver Regeneration and Cell Transplantation for End-Stage Liver Disease". Biomolecules 11, n. 12 (20 dicembre 2021): 1907. http://dx.doi.org/10.3390/biom11121907.

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Liver transplantation is the only curative option for end-stage liver disease; however, the limitations of liver transplantation require further research into other alternatives. Considering that liver regeneration is prevalent in liver injury settings, regenerative medicine is suggested as a promising therapeutic strategy for end-stage liver disease. Upon the source of regenerating hepatocytes, liver regeneration could be divided into two categories: hepatocyte-driven liver regeneration (typical regeneration) and liver progenitor cell-driven liver regeneration (alternative regeneration). Due to the massive loss of hepatocytes, the alternative regeneration plays a vital role in end-stage liver disease. Advances in knowledge of liver regeneration and tissue engineering have accelerated the progress of regenerative medicine strategies for end-stage liver disease. In this article, we generally reviewed the recent findings and current knowledge of liver regeneration, mainly regarding aspects of the histological basis of regeneration, histogenesis and mechanisms of hepatocytes’ regeneration. In addition, this review provides an update on the regenerative medicine strategies for end-stage liver disease. We conclude that regenerative medicine is a promising therapeutic strategy for end-stage liver disease. However, further studies are still required.

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Paatela, Ellen, Dane Munson e Nobuaki Kikyo. "Circadian Regulation in Tissue Regeneration". International Journal of Molecular Sciences 20, n. 9 (8 maggio 2019): 2263. http://dx.doi.org/10.3390/ijms20092263.

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Circadian rhythms regulate over 40% of protein-coding genes in at least one organ in the body through mechanisms tied to the central circadian clock and to cell-intrinsic auto-regulatory feedback loops. Distinct diurnal differences in regulation of regeneration have been found in several organs, including skin, intestinal, and hematopoietic systems. Each regenerating system contains a complex network of cell types with different circadian mechanisms contributing to regeneration. In this review, we elucidate circadian regeneration mechanisms in the three representative systems. We also suggest circadian regulation of global translational activity as an understudied global regulator of regenerative capacity. A more detailed understanding of the molecular mechanisms underlying circadian regulation of tissue regeneration would accelerate the development of new regenerative therapies.

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Davenport, R. J. "Regenerating Regeneration". Science of Aging Knowledge Environment 2004, n. 35 (1 settembre 2004): ns6. http://dx.doi.org/10.1126/sageke.2004.35.ns6.

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Hoban, M., e P. Beresford. "Regenerating regeneration". Community Development Journal 36, n. 4 (1 ottobre 2001): 312–20. http://dx.doi.org/10.1093/cdj/36.4.312.

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Alibardi, Lorenzo. "Regeneration or Scarring Derive from Specific Evolutionary Environmental Adaptations of the Life Cycles in Different Animals". Biology 12, n. 5 (17 maggio 2023): 733. http://dx.doi.org/10.3390/biology12050733.

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The ability to heal or even regenerate large injuries in different animals derives from the evolution of their specific life cycles during geological times. The present, new hypothesis tries to explain the distribution of organ regeneration among animals. Only invertebrates and vertebrates that include larval and intense metamorphic transformations can broadly regenerate as adults. Basically, regeneration competent animals are aquatic while terrestrial species have largely or completely lost most of the regeneration ability. Although genomes of terrestrial species still contain numerous genes that in aquatic species allow a broad regeneration (“regenerative genes”), the evolution of terrestrial species has variably modified the genetic networks linking these genes to the others that evolved during land adaptation, resulting in the inhibition of regeneration. Loss of regeneration took place by the elimination of intermediate larval phases and metamorphic transformations in the life cycles of land invertebrates and vertebrates. Once the evolution along a specific lineage generated species that could no longer regenerate, this outcome could not change anymore. It is therefore likely that what we learn from regenerative species will explain their mechanisms of regeneration but cannot or only partly be applied to non-regenerative species. Attempts to introduce “regenerative genes” in non-regenerative species most likely would disorder the entire genetic networks of the latter, determining death, teratomas and cancer. This awareness indicates the difficulty to introduce regenerative genes and their activation pathways in species that evolved genetic networks suppressing organ regeneration. Organ regeneration in non-regenerating animals such as humans should move to bio-engineering interventions in addition to “localized regenerative gene therapies” in order to replace lost tissues or organs.

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Bergamini, Giulia, Mohamad Ahmad, Marina Cocchi e Davide Malagoli. "A New Protocol of Computer-Assisted Image Analysis Highlights the Presence of Hemocytes in the Regenerating Cephalic Tentacles of Adult Pomacea canaliculata". International Journal of Molecular Sciences 22, n. 9 (9 maggio 2021): 5023. http://dx.doi.org/10.3390/ijms22095023.

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In humans, injuries and diseases can result in irreversible tissue or organ loss. This well-known fact has prompted several basic studies on organisms capable of adult regeneration, such as amphibians, bony fish, and invertebrates. These studies have provided important biological information and helped to develop regenerative medicine therapies, but important gaps concerning the regulation of tissue and organ regeneration remain to be elucidated. To this aim, new models for studying regenerative biology could prove helpful. Here, the description of the cephalic tentacle regeneration in the adult of the freshwater snail Pomacea canaliculata is presented. In this invasive mollusk, the whole tentacle is reconstructed within 3 months. Regenerating epithelial, connective, muscular and neural components are already recognizable 72 h post-amputation (hpa). Only in the early phases of regeneration, several hemocytes are retrieved in the forming blastema. In view of quantifying the hemocytes retrieved in regenerating organs, granular hemocytes present in the tentacle blastema at 12 hpa were counted, with a new and specific computer-assisted image analysis protocol. Since it can be applied in absence of specific cell markers and after a common hematoxylin-eosin staining, this protocol could prove helpful to evidence and count the hemocytes interspersed among regenerating tissues, helping to unveil the role of immune-related cells in sensory organ regeneration.

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Batwa, Mohammed, Rand Bakhsh, Zainab Alghamdi, Khaled Ageely, Abdullah Alzahrani, Abdullah Alshahrani, Khalid Mujthil et al. "Regenerative Therapies in the Treatment of Periodontal Defects". JOURNAL OF HEALTHCARE SCIENCES 03, n. 08 (2023): 254–60. http://dx.doi.org/10.52533/johs.2023.30802.

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Regenerative therapies in periodontics have shown great potential in restoring damaged periodontal tissues. Techniques such as guided tissue regeneration (GTR) and guided bone regeneration (GBR) have been effective in promoting the regeneration of periodontal ligament, cementum, and alveolar bone. These approaches create a conducive environment for cell repopulation and exclusion of non-osteogenic cells, leading to successful periodontal tissue regeneration. Tissue engineering approaches, utilizing stem cells, growth factors, and biomaterial scaffolds, have also shown promise in regenerating multiple periodontal tissues simultaneously. However, challenges such as membrane exposure and infection need to be addressed. Emerging regenerative techniques, including enamel matrix derivatives (EMDs), stem cell-based therapies, growth factor delivery systems, and gene therapies, offer innovative strategies for periodontal defect treatment. Optimization of delivery systems, refinement of biomaterials, and advancements in gene therapy and tissue-specific biomaterials may further enhance the regenerative capacity of periodontal tissues. Despite challenges, regenerative therapies have the potential to revolutionize periodontics and improve clinical outcomes by addressing the root cause of periodontal diseases and promoting long-lasting tissue regeneration.

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Maganur, Prabhadevi. "Dental Pulp Stem Cells in Regenerative Therapy". TEXILA INTERNATIONAL JOURNAL OF ACADEMIC RESEARCH 10, n. 2 (28 aprile 2023): 70–77. http://dx.doi.org/10.21522/tijar.2014.10.02.art007.

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Stem cells, also known as progenitor/precursor cells, have the unique trait of self-renewal and multi-lineage differentiation. Dental stem cells (DSCs) are holding a pivotal role during recent times as they thrive as the cornerstone for the development of cell transplantation therapies that correct periodontal disorders and damaged dentin. DSCs are used therapeutically for different organ systems and numerous diseases, including neurological disorders, diabetes, liver disease, bone tissue engineering, and dentistry. In dentistry, the focus is on predominantly regenerating the pulp and damaged dentin, repairing perforations, and periodontal regenerations. Above all, whole tooth regeneration has been constantly under research. The next decade could be a crucial junction where huge leaps in stem cell-based regenerative therapies could become a reality with successful tissue engineering therapies this could be a biological alternative to synthetic materials that are in use currently. But dental stem cells have their share of challenges for which the research must happen effectively adhering to social responsibilities at all levels. Keywords: Stem cells, Regeneration, Regenerative therapy, SHED.

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Gupta, Samudra, Suman Dutta e Subhra Prakash Hui. "Regenerative Potential of Injured Spinal Cord in the Light of Epigenetic Regulation and Modulation". Cells 12, n. 13 (22 giugno 2023): 1694. http://dx.doi.org/10.3390/cells12131694.

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A spinal cord injury is a form of physical harm imposed on the spinal cord that causes disability and, in many cases, leads to permanent mammalian paralysis, which causes a disastrous global issue. Because of its non-regenerative aspect, restoring the spinal cord’s role remains one of the most daunting tasks. By comparison, the remarkable regenerative ability of some regeneration-competent species, such as some Urodeles (Axolotl), Xenopus, and some teleost fishes, enables maximum functional recovery, even after complete spinal cord transection. During the last two decades of intensive research, significant progress has been made in understanding both regenerative cells’ origins and the molecular signaling mechanisms underlying the regeneration and reconstruction of damaged spinal cords in regenerating organisms and mammals, respectively. Epigenetic control has gradually moved into the center stage of this research field, which has been helped by comprehensive work demonstrating that DNA methylation, histone modifications, and microRNAs are important for the regeneration of the spinal cord. In this review, we concentrate primarily on providing a comparison of the epigenetic mechanisms in spinal cord injuries between non-regenerating and regenerating species. In addition, we further discuss the epigenetic mediators that underlie the development of a regeneration-permissive environment following injury in regeneration-competent animals and how such mediators may be implicated in optimizing treatment outcomes for spinal cord injurie in higher-order mammals. Finally, we briefly discuss the role of extracellular vesicles (EVs) in the context of spinal cord injury and their potential as targets for therapeutic intervention.

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Tesi sul tema "Regeneration"

Bhavsar, Rital. "Newt Lens Regeneration: Role of Oct-4 in Newt Regenerating Tissue and Proteome Analysis of Regeneration Competent Vs. Regeneration Incompetent Cells". University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1397131576.

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Morgan, James. "Gambling with regeneration : seaside resort regeneration and casino development". Thesis, University of Westminster, 2013. https://westminsterresearch.westminster.ac.uk/item/8z0z2/gambling-with-regeneration-seaside-resort-regeneration-and-casino-development.

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The United Kingdom’s seaside resorts are in decline. This has been addressed by various regeneration strategies. The Gambling Act 2005 threw a potential lifeline to some seaside resorts that wished to utilise casinos as cultural regeneration tools. However, this is a unique example of a regeneration lever that generates new policy processes. This thesis explores the development and passage of the casino regeneration strategy in three seaside resorts: Great Yarmouth, Scarborough and Torbay. All of these resorts had differing cultural and socio-economic contexts. Linking the perceptions of this type of cultural development demanded a specific methodology. Casinos are cultural objects and social spaces. The intersection of the cultural, economic and social demanded an overarching theoretical guide within which these perceptions could be explored. Of particular value was the work of Lefebvre in his core work on ‘The Production of Space’ (1991) and du Gay et al. ‘Circuit of Culture’ (1997). How policymakers, business and community representatives conceived casino spaces was explored through the regulatory environment at the national, regional and local levels of governance. The perception of how casino spaces should be produced to arrive at culturally compatible representations and identities for consumption followed. It was found that the regulatory environment was experimental and confusing to some. However, most interviewees wanted to see large casino complexes developed in their towns. Potential moral, social and cultural hazards were perceived but not to have been fully considered in the government’s strategy, however the economic advantages outweighed these. This study argues that further research is required into this contested cultural activity, and the spaces that house that activity once they are built and operating.

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Raven, Alexander Philip. "Impairing hepatocyte regeneration to determine the regenerative capacity of the biliary epithelium". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31177.

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Liver injury stimulates hepatocyte proliferation, regenerating the liver through self-replication. In cases where there is severe, repetitive, parenchymal damage, as seen in human chronic liver disease, hepatocyte mediated regeneration becomes impaired. In this setting it is currently unclear whether endogenous biliary epithelial cells can repopulate the hepatocyte compartment. This thesis therefore aimed to address this point by lineage tracing the main two liver epithelia populations on a background of impaired hepatocyte regeneration. To impair regeneration, an Itgb1 transgene was specifically deleted, conditionally, from the hepatocyte epithelium. Long-term loss of β1-Integrin alone or with additional injury caused an epithelial ductular reaction of biliary origin. Alongside β1-Integrin ablation, the hepatocyte epithelium was also labelled with a heritable ROSA26LSLtdTomato reporter. Impaired hepatocyte regeneration mediated by β1- integrin ablation resulted in 25% of hepatocytes becoming tdTomato negative (non-hepatocyte derived). To verify that the non-hepatocyte mediated regeneration was originating from the biliary epithelium, anti-Itgb1 RNAi was administrated to K19CreERT LSLtdTomato mice. Resulting in tdTomato positive hepatocytes that had differentiated from the labelled tdTomato positive biliary epithelial cells. In summary, this thesis demonstrates that hepatocyte β1-Integrin ablation combined with toxic damage causes marked ductular reactions and results in a substantial regeneration of functional hepatocytes from the biliary epithelium.

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Moreira, Ana Isabel Magalhães. "Revascularização pulpar". Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4598.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária
Em Medicina Dentária a taxa de incidência de patologia pulpar é elevada. Atualmente o tratamento realizado nestes casos passa pelo tratamento endodôntico não cirúrgico e obturação do sistema tridimensional de canais do dente permanente e maturo necrosado. Quando o tecido pulpar sofre necrose o prognóstico do dente está comprometido. Até então a abordagem terapêutica nestes casos passa por tratamento dos canais radiculares no caso de dentes com ápices maduros, apexificação em dentes com ápice imaturo ou extração. Apesar de estas modalidades terapêuticas apresentarem elevadas taxas de sucesso, a presença de uma polpa vital é fundamental para manter a homeostase e longevidade da peça dentária. Uma forma de terapia ideal pode consistir em abordagens regenerativas que consistem na remoção e substituição da polpa danificada ou necrosada por tecido pulpar saudável de forma a revitalizar o dente. Para atingir este objetivo os investigadores têm estudado diversas técnicas: revascularização por coágulo sanguíneo, terapia com células estaminais, implantação pulpar, implantação de scaffold, impressão tridimensional celular, scaffold injetável e terapia genética. Este tipo de tratamentos envolve combinação de desinfeção, desbridamento do canal afetado, utilização de células estaminais adultas, scaffolds e fatores de crescimento. Pode ser necessário também o alargamento apical para permitir a revascularização. Com esta revisão pretende-se compreender melhor o procedimento de revascularização pulpar no geral, vantagens e desvantagens, sua aplicabilidade na prática clinica diária e aferir sobre os resultados obtidos na literatura. Apesar de os desafios para a introdução das técnicas regenerativas como tratamento alternativo de dentes necrosados serem substancias, estas podem ser benéficas pois apresentam a possibilidade de restabelecer a funcionalidade pulpar, tornando a polpa vital capaz de promover a correta maturação apical. A inexistência de um protocolo fiável de atuação que permita a criação das condições necessárias para que ocorra a revitalização do tecido torna este tratamento pouco utilizado como tratamento alternativo na prática clinica. Assim, mais estudos são necessários para que futuramente seja possível elaborar um protocolo que possibilite a introdução das técnicas de revascularização pulpar na prática clinica diária. Dentistry in the incidence rate of pulpal pathology is high. Currently the treatment performed in these cases through the nonsurgical endodontic treatment and obturation of the three-dimensional system of permanent tooth and necrosed mature channels. When the pulp tissue undergoes necrosis prognosis of the tooth is compromised. Until then the therapeutic approach in these cases involves treatment of root canals in the case of teeth with mature apices, apexificação in teeth with immature apex or extraction. Despite these therapeutic modalities have high success rates, the presence of a vital pulp is essential to maintain homeostasis and longevity of tooth number. An ideal form of therapy might consist of regenerative approaches involving the removal and replacement of damaged or necrotic pulp by healthy pulp tissue to revitalize the tooth. To achieve this goal researchers have studied various techniques: revascularization by a blood clot, stem cell therapy, pulp, implantation of scaffold, cell dimensional printing, injectable scaffold and gene therapy. This type of treatment involves combination of disinfection, debridement of the affected channel, use of adult stem cells, scaffolds and growth factors. You may also need the apical enlargement to allow revascularization. With this revision is intended to better understand the procedure of pulp revascularization in general, advantages and disadvantages, its applicability in daily clinical practice and benchmark the results obtained in the literature. Although the challenges for the introduction of regenerative techniques as an alternative treatment of necrotic teeth are substances, these can be beneficial since they have the ability to restore functionality pulp making the vital pulp capable of promoting correct apical maturation. The absence of a reliable protocol operation that allows the creation of conditions necessary for the revitalization of the fabric makes this treatment occurs rarely used as an alternative treatment in clinical practice. Thus, further studies are needed, in future be possible to develop a protocol which would include the pulp revascularization in endodontics.

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Hudson, Daniel Alexander. "Regeneration architecture". Thesis, Montana State University, 2010. http://etd.lib.montana.edu/etd/2010/hudson/HudsonD0510.pdf.

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In a world of excess, people rarely stop to realize their impact on their environments. Our built environment is especially feeling the effect of our irresponsibility, and the solution is only a matter of re-wiring our perceptions of energy usage. Many technologies make it possible to have the impossible, but nobody stops to question whether or not these advances are beneficial. A presumably sustainable system turned out to be one of the most energy wasteful ones in existence. In the complex process of getting food from the field to your house, the best solution is to simplify. Nature will do most of the work; we need to learn to work with it. Current building practices can benefit greatly from this concept, to rethink the existing process by simply cutting out the unneeded steps and using the free energy available to us every day. Our values need to change. Because the corporation controls so much of our daily lives, they are the ones that will bring about the change in consciousness we desperately need. By re-designing Sysco headquarters to do everything that the company claims to do (and currently doesn't), and interact with the public in a new and radical way, not only can we make changes to how we think about the built environment, but we can also start to show that a change in awareness is entirely possible. If we can change the values of those that make the biggest differences in our world, then we've effectively changed an entire populations' way of thinking.

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Pronchuk, Myrna Lee. "Aural Regeneration". Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/art_design_theses/118.

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AURAL REGENERATION by MYRNA LEE PRONCHUK Under the Direction of Craig Dongoski ABSTRACT The aim of this thesis is to survey the abstraction of the human experience obscuring the confines between form and expression, sound and visual, experience and imitation. In establishing multiple levels of communication, I began with gathering discarded found objects, which I repurposed through building hybrid musical sculptures. The act of mark making mapped out systems and direction, and escalated into a form of hybrid musical notation. Both forms of hybrids informed each other in its development process. When the hybrid instruments and notation were placed in an environment together with the elements of Digital Signal Processing (DSP), it created a natural progression for performance. The objects required interaction: to be hit, tapped, bowed and plucked, with their sounds processed through DSP, and projected back into the audience, who participated in creating interactivity. In producing mechanical musical instruments, along with mark making, installation and experimental sound recordings, a platform is established allowing for a dialogue between audio and visual elements, and human experience.

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Nearing, Marie. "The Role of the Regenerating Protein Family on Skeletal Muscle Regeneration". Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/268516.

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Skeletal muscle regeneration is dependent upon the influences of intrinsic and extrinsic factors that stimulate satellite cells. Regenerating proteins are upregulated at the onset of trauma or inflammation in the pancreas, gastrointestinal tract, liver, neural cells and other tissues. Studies have shown that Reg proteins have a mitogenic, anti-apoptotic and anti-inflammatory function in damaged tissues and is necessary for normal progression of regeneration. As skeletal muscle is also able to regenerate itself at a rapid rate, it seems highly likely that Reg proteins function to promote myogenesis in skeletal muscle regeneration. Therefore, the goal of our research was to characterize the expression of the Reg proteins and receptor in regenerating skeletal muscle and satellite cells, investigate the effect of exogenous Reg protein on myogenesis, and to examine direct Reg protein effect on satellite cell activity. To determine whether Reg proteins participate in skeletal muscle regeneration, mice were injected with marcaine in their tibialis anterior muscles to induce skeletal muscle damage. The gene expression analysis of undamaged and marcaine-damaged tibialis anterior muscles and mice satellite cells showed that Reg I, II, IIIα, IIIγ, IV and EXTL3 genes are present during skeletal muscle regeneration and satellite cells significantly express Reg I, IIIα, IIIγ and EXTL3. As Reg I and IIIα are most prevalent in vivo and in vitro respectively, we advocate these isoforms as the predominant candidates in skeletal muscle regeneration. To determine the effect of exogenous Reg protein on myogenesis, we performed gene expression and muscle morphometry analysis of Reg IIIα or PBS injected tibialis anterior muscles. Interestingly, our results indicate that the addition of Reg IIIα to damaged muscles inhibited myogenesis. To determine the direct effect of Reg protein on myogenic stem cell activity, Reg proteins were added to mice satellite cells and C2C12 cells. Results from these studies were inconclusive due to the failure of known positive and negative controls. Overall, our studies suggest that Reg proteins contribute to skeletal muscle regeneration; however, as an overabundance of Reg IIIα in regenerating tissues may have inhibited myogenesis, it is imperative that other isoforms or lower concentrations be investigated.

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Pillay, Danvir. "Active regeneration : Re-activating Johannesburg's mining belt through a contextual regenerative theory". Diss., University of Pretoria, 2018. http://hdl.handle.net/2263/63652.

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This dissertation investigates the latent potential of the mining belt in Johannesburg through a regenerative theory, by placing a catalytic intervention which respects the heritage of the mining belt, with a focus on the ecology and the socio-economic value of the land has, thereby turning a liability into an asset. This intervention is seen as the first point of acupuncture in a long rehabilitation process and focuses on using this space to deal with context specific issues. The proposed intervention will investigate the potential of architecture to activate a harmed dormant space in the realm of a decentralized city node. It recognizes the potential of the currently fragmented mining belt to become a gateway to the South of Johannesburg, and embraces an opportunity to restitch the urban fabric.
Mini Dissertation MArch(Prof)--University of Pretoria, 2018.
Architecture
MArch(Prof)
Unrestricted

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MacLaren, Robert E. "Optic nerve regeneration". Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318923.

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Tausczik, Carl P. (Carl Philip). "Magnetically active regeneration". Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/14917.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1987.
MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERING
Bibliography: leaves 126-134.
by Carl P. Tausczik.
Ph.D.

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Più fonti

Libri sul tema "Regeneration"

M, Carlson Bruce, a cura di. Principles of regenerative biology. Amsterdam: Elsevier/Academic Press, 2007.

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Barker, Pat. Regeneration. London: Viking, 1991.

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Barker, Pat. Regeneration. Boston: Compass Press, 1996.

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Barker, Pat. Regeneration. New York, N.Y., U.S.A: Dutton, 1992.

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Czerneda, Julie. Regeneration. New York: Penguin USA, Inc., 2009.

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Singleton, Linda Joy. Regeneration. Waterville, Me: Thorndike Press, 2002.

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Barker, Pat. Regeneration. New York: Penguin USA, Inc., 2009.

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1819-1886, Ker John, a cura di. Regeneration. 2^a ed. London: Hodder and Stoughton, 1985.

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Ludlow, John W., e Joydeep Basu. Organ regeneration: Methods and protocols. New York: Humana, 2013.

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Capitoli di libri sul tema "Regeneration"

Ferrario, Cinzia, Yousra Ben Khadra, Michela Sugni, M. Daniela Candia Carnevali, Pedro Martinez e Francesco Bonasoro. "Studying Echinodermata Arm Explant Regeneration Using Echinaster sepositus". In Methods in Molecular Biology, 263–91. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2172-1_14.

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AbstractEchinoderms are marine invertebrate deuterostomes known for their amazing regenerative abilities throughout all life stages. Though some species can undergo whole-body regeneration (WBR), others exhibit more restricted regenerative capabilities. Asteroidea (starfish) comprise one of the few echinoderm taxa capable of undergoing WBR. Indeed, some starfish species can restore all tissues and organs not only during larval stages, but also from arm fragments as adults. Arm explants have been used to study cells, tissues and genes involved in starfish regeneration. Here, we describe methods for obtaining and studying regeneration of arm explants in starfish, in particular animal collection and husbandry, preparation of arm explants, regeneration tests, microscopic anatomy techniques (including transmission electron microscopy, TEM) used to analyze the regenerating explant tissues and cells plus a downstream RNA extraction protocol needed for subsequent molecular investigations.

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Sinigaglia, Chiara, Alexandre Alié e Stefano Tiozzo. "The Hazards of Regeneration: From Morgan’s Legacy to Evo-Devo". In Methods in Molecular Biology, 3–25. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2172-1_1.

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AbstractIn his prominent book Regeneration (1901), T.H. Morgan’s collected and synthesized theoretical and experimental findings from a diverse array of regenerating animals and plants. Through his endeavor, he introduced a new way to study regeneration and its evolution, setting a conceptual framework that still guides today’s research and that embraces the contemporary evolutionary and developmental approaches.In the first part of the chapter, we summarize Morgan’s major tenets and use it as a narrative thread to advocate interpreting regenerative biology through the theoretical tools provided by evolution and developmental biology, but also to highlight potential caveats resulting from the rapid proliferation of comparative studies and from the expansion of experimental laboratory models. In the second part, we review some experimental evo-devo approaches, highlighting their power and some of their interpretative dangers. Finally, in order to further understand the evolution of regenerative abilities, we portray an adaptive perspective on the evolution of regeneration and suggest a framework for investigating the adaptive nature of regeneration.

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Müller, Werner A., e Monika Hassel. "Stammzellen, Regeneration, regenerative Medizin". In Entwicklungsbiologie und Reproduktionsbiologie des Menschen und bedeutender Modellorganismen, 457–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28383-3_18.

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Müller, Werner A., e Monika Hassel. "Stammzellen, Regeneration, regenerative Medizin". In Entwicklungsbiologie und Reproduktionsbiologie des Menschen und bedeutender Modellorganismen, 511–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-55534-7_18.

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Zattara, Eduardo E., e Fernando A. Fernández-Alvarez. "Collecting and Culturing Lineus sanguineus to Study Nemertea WBR". In Methods in Molecular Biology, 227–43. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2172-1_12.

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AbstractWhole-body regeneration, the ability to reconstruct complete individuals from small fragments, is rare among ribbon worms (phylum Nemertea) but present in the pilidiophoran species Lineus sanguineus. This species can regenerate complete individuals from a tiny midbody section, and even from a quarter of a piece, provided it retains a fragment of a lateral nerve cord. While a few other unrelated species of ribbon worms are also excellent regenerators, L. sanguineus is unique in having evolved its regenerative abilities quite recently and thus offers an exceptional opportunity to gain insight into the evolutionary mechanisms of regeneration enhancement. Interestingly, both its sister species Lineus lacteus and Lineus pseudolacteus, a third species derived from the recent hybridization of the other two, differ in their regeneration abilities: while L. lacteus is uncapable of regenerating a lost head, L. pseudolacteus is capable of anterior regeneration, albeit at a slower rate than L. sanguineus. L. sanguineus has a worldwide distribution in temperate shores of both hemispheres, is readily found at intertidal habitats, and can survive, feed and be bred through asexual replication with minimal effort in laboratory settings. All the above make this species a superb candidate for studies of regenerative biology. In this chapter, we present protocols to collect, identify and breed L. sanguineus to study the extraordinary whole-body regeneration abilities found in this species.

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Simon, Stephane, e Michel Goldberg. "Regenerative Endodontics: Regeneration or Repair?" In The Dental Pulp, 267–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-55160-4_19.

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Mueller, Werner A., Monika Hassel e Maura Grealy. "Stem Cells, Regeneration, Regenerative Medicine". In Development and Reproduction in Humans and Animal Model Species, 517–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43784-1_18.

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Thieme, Kurt H. "Regeneration". In Das ABC des Selbstmanagements, 86–89. Wiesbaden: Gabler Verlag, 1995. http://dx.doi.org/10.1007/978-3-322-91142-1_20.

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Tomasits, Josef, e Paul Haber. "Regeneration". In Leistungsphysiologie, 129–30. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-3782-6_9.

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Canale, Enrico D., Gordon R. Campbell, Joseph J. Smolich e Julie H. Campbell. "Regeneration". In Cardiac Muscle, 194. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-50115-9_9.

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Atti di convegni sul tema "Regeneration"

Lynch, Kristen, e Tabassum Ahsan. "Proliferation of Cells From a Mouse Model of Regeneration". In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14305.

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The ability to induce limb regeneration in humans is of growing interest in the field of regenerative medicine, particularly due to the increased number of amputees among military veterans. Unfortunately, mammals have limited regenerative capabilities as compared to amphibians, which can re-establish complex structures after traumatic injury. There have been a few clinically documented cases of digit regeneration in children [1], indicating that the potential to regenerate is not completely absent in humans. Mammalian models of epimorphic regeneration is primarily limited to the mouse digit, which has a level-specific response in that amputation at the terminal phalangeal element (P3) results in regeneration, but not at the next more proximal joint (P2) (Figure 1). Recently primary stromal cells were isolated from each of these mouse joints (P3 and P2, respectively) [2], which provides a unique opportunity to utilize in vitro techniques to identify differences in one of the phenotypes prevalent at the amputation plane of a regenerating and non-regenerating region.

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Huang, Francis F., e Tim Naumowicz. "Thermodynamic Study of an Indirect Fired Air Turbine Cogeneration System With Regeneration". In ASME 1987 International Gas Turbine Conference and Exhibition. American Society of Mechanical Engineers, 1987. http://dx.doi.org/10.1115/87-gt-34.

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A previous study of an indirect fired air turbine cogeneration system has been extended to include the concept of regeneration. The effect of regenerator effectiveness and full regeneration as well as partial regeneration on system performance parameters (such as fuel utilization efficiency, power-to-heat ratio and second-law efficiency) are examined. An important conclusion of this study is that a regenerative gas turbine cogeneration system is capable of producing large power-to-heat ratios for various process conditions requiring the use of only moderate compressor compression ratio and moderately effective regenerators. It appears that this is an attractive system which could compete in a market that is currently dominated by internal combustion engines when a viable fludized bed air heater is available.

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Midlam-Mohler, Shawn, e Yann Guezennec. "Modeling of a Partial-Flow, Diesel, Lean NOx Trap Systems". In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-80834.

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Lean NOx Traps (LNTs) have shown promise for Diesel applications; however, production implementation in vehicles poses a number of challenges. Much of the literature reports on LNT systems in which the catalyst always receives the full flow of exhaust from the engine, referred here as full-flow regeneration systems. Another implementation of the LNT is one in which the exhaust can be partially or fully diverted from the catalyst to allow local introduction of the necessary reductants for regeneration. The physical aspects of one such system, as well as a control-oriented model are presented with experimental validation. In the system described here, the exhaust flow is diverted around the catalyst during regenerations. In the low exhaust flow through the catalyst, reductant is added (Diesel fuel typically) which provides the rich conditions for regenerating the trap. This allows the engine to continue to run in normal lean mode, which overcomes one of the major challenges for full-flow regeneration systems. Successful regeneration with liquid Diesel fuel is strongly dependent on catalyst temperature, which is addressed by proper thermal management of the system through the addition of fuel prior to regeneration. In this paper, both component level and vehicle level simulations are presented in terms of fuel economy versus NOx reduction. Several different system configurations and control strategies are compared.

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Palmieri, Stefania, Mario Bisson, Alessandro Ianniello, Riccardo Palomba e Luca Botta. "Local resilience through Design: a theoretical framework for territorial regeneration." In ServDes.2023 Entanglements & Flows Conference: Service Encounters and Meanings Proceedings, 11-14th July 2023, Rio de Janeiro, Brazil. Linköping University Electronic Press, 2023. http://dx.doi.org/10.3384/ecp203015.

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The technological revolution and the current desire to reconnect with the land provide opportunities to design innovative relationships between citizens and communities for the development of regenerative activities and practices that lead to the creation of common welfare. The rural context is inclined to design strategies that involve significant changes in lifestyle by intervening in various fields with practices and activities aimed at territorial regeneration. Through different approaches, value and trust are created to co-design possible futures and transitional pathways to them. The aim of the paper is to propose a theoretical framework that considers the methodologies and activities typical of design discipline, creating guidelines for the application of innovative processes, with the intention of regenerating a place undergoing social abandonment and environmental deterioration.

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Si, Junping, Mingyan Tong, Wenhua Yang e Gang Huang. "Study on Thermal Characteristics of the Regenerative Heat Exchanger". In 2016 24th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/icone24-60380.

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The regenerative heat exchanger is widely used in nuclear power plants and research reactors. It is composed of the regeneration section and the cooling section. The heat transfer mainly occurs at the cooling section, while the regeneration section is designed to reduce the temperature difference between the hot and cold fluids and weaken the damage to the heat exchanger due to the existence of thermal stress. Meanwhile, some heat is also can be recovered through the regeneration section. This paper mainly aims to analyze the thermal characteristics of the regenerative heat exchanger according to its structure properties, and provides some suggestions for regenerative heat exchanger design based on the influence of some key factors on thermal characteristics. The results show that improving the outlet temperature in the regeneration section primary side can both reduce the heat exchange areas of the regeneration section and the cooling section, but this will rise thermal shock and increase the operation safety risk. The baffles arrangement will enhance heat exchange capacity, and the heat exchange area decreases with the baffle gap height increasing. With the heat exchange area margin of the regeneration section improvement, the actual power will gradually reduce. The measures, including increasing secondary water flow or taking a corresponding margin about 52.8%∼59.2% that of the regeneration section for the cooling section heat exchange area, can be taken to overcome the adverse effects of the margin on the regenerative heat exchanger. More heat exchange areas of the regeneration section and the cooling section are required to satisfy the rated power with the fouling thermal resistance of the primary water increasing. Moreover, adopting a lower fouling coefficient favors the generative heat exchanger running under the design power.

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Park, Chan-Woo, e Massoud Kaviany. "Evaporation-Combustion Affected by In-Cylinder, Reciprocating Porous Regenerator". In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1559.

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Abstract An existing in-cylinder thermal regeneration concept for the Diesel engines is examined for the roles of the porous regenerator motion and the fuel injection strategies on the fuel evaporation and combustion and on the engine efficiency. While the heated air emanating from the regenerator enhances fuel evaporation resulting in a superadiabatic combustion (thus increasing thermal efficiency), the corresponding increase in the thermal NOx is undesirable. A multi-gas-zone and a single-step reaction model are used with a Lagrangian droplet tracking model that allows for filtration by the regenerator. A thermal efficiency of 52 percent is predicted, compared to 45 percent of the conventional Diesel engines. The optimal regenerative cooling stroke occurs close to the peak flame temperature, thus increasing the superadiabatic flame temperature and the peak pressure, while decreasing the expansion stroke pressure and the pressure drop through the regenerator. During the regenerative heating stroke, the heated air enhances the droplet evaporation, resulting in a more uniform, premixed combustion and a higher peak pressure, and thus a larger mechanical work.

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Li, Jun, Xin Wang e Baochun Li. "Pipelined Regeneration with Regenerating Codes for Distributed Storage Systems". In 2011 International Symposium on Network Coding (NetCod). IEEE, 2011. http://dx.doi.org/10.1109/isnetcod.2011.5978915.

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Bekair, K. "Softener Regeneration Optimization". In SPE Water Lifecycle Management Conference and Exhibition. SPE, 2024. http://dx.doi.org/10.2118/219071-ms.

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Abstract A new innovative idea, which has been filed for patent, is simply utilizing waste water, which is RO membrane reject, in the process of regenerating a softener unit. This unit's product, soft water, is utilized instead of raw water in cooling towers since it has a lower hardness than raw water, resulting in a lower usage of water in the cooling system. The principle of softener units is based on ion-to-ion exchange between the hardness material, which is mainly calcium and magnesium, and sodium. After utilizing the softener unit, the resins will be saturated with hardness materials; hence, a regeneration process would be required to make the unit available again for operation. The new innovative procedure involves replacing the raw water in the regeneration process with RO reject. Theoretically, one of the challenges that the idea encountered was the high concentration of hardness materials in the RO reject. The analysis showed that the performance of the regeneration process when utilizing RO reject will not be affected. Based on the theoretical evaluation, a six-month trial was conducted, and it was concluded that the idea was successful. The quantifiable benefit of applying such an innovative idea is a reduction in the overall utilization of raw water in the regeneration process by 40%, which is 15 million gallons of fresh water per year, which corresponds to a dollar value of $150,000 per annum.

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Hahn, Kim HongYoun. "Stellar Regeneration". In Breaking Boundaries. Iowa State University Digital Press, 2022. http://dx.doi.org/10.31274/itaa.13377.

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Carapellucci, Roberto, e Lorena Giordano. "Enhancing Energy and Economic Performances of Combined Cycle Power Plants by Means of Gas-Cycle Regeneration". In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-38297.

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Efficiency improvement in the gas turbine sector has been mainly driven by increasing the turbine inlet temperature and compressor pressure ratio. For a fixed technology level, a further efficiency gain can be achieved through the utilization of waste thermal energy. Regeneration is an internal recovery technique that allows the reduction of heat input required at combustor, by preheating the air at compressor outlet. Under certain operating conditions, the temperature of exhaust gas leaving the regenerator is still enough high to allow the steam production via an heat recovery steam generator (HRSG). Regeneration in steam-gas power plants (CCGT) has the potential to enhance thermal efficiency, but reduces the margins for external recovery and then the bottoming steam cycle capacity. Moreover, the reduction of exhausts temperature at gas turbine outlet requires the reconsideration of HRSG operating parameters, in order to limit the increase of waste heat at the stack. The aim of this study is to explore the potential benefits that regeneration in the gas cycle gives on the whole steam-gas power plant. The extent of energy and economic performances improvement is evaluated, varying the gas turbine specifications and the layout and operating conditions of HRSG. Hence simple and regenerative configurations based on single and multi-pressure HRSG are compared, focusing on efficiency, specific CO2 emissions and unit cost of electricity (COE).

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Rapporti di organizzazioni sul tema "Regeneration"

Paul, Satashree. Stem Cell Therapy: A Promise to Cardiac Regeneration. Science Repository OÜ, ottobre 2020. http://dx.doi.org/10.31487/sr.blog.09.

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Cell-based regenerative therapies became a promising treatment for heart failure. Cardiac regeneration is a broad effort with cutting-edge science that aims to repair irreversibly damaged heart tissue, using stem cell therapy.

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Research, Gratis. Regenerative Medicine: A Breakthrough in the Branch of Medicine. Gratis Research, novembre 2020. http://dx.doi.org/10.47496/gr.blog.04.

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Regenerative medicine, being an interdisciplinary field, applies the principle of engineering and life science to promote regeneration. Regenerative medicine supports the treatment of chronic diseases and acute insults

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J. Lin. Regeneration Heat Exchange. Office of Scientific and Technical Information (OSTI), luglio 2003. http://dx.doi.org/10.2172/828247.

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Crisp, Richard, David Leather, Joe McMullan, Sarah Pearson e Ian Wilson. Review of neighbourhood regeneration. Sheffield Hallam University, novembre 2023. http://dx.doi.org/10.7190/cresr.2023.6940123501.

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McIlroy, R. A., P. B. Probert, E. J. Lahoda, W. M. Swift, D. M. Jackson, J. Prasad, J. Martin et al. MHD (Magnetohydrodynamics) recovery and regeneration. Office of Scientific and Technical Information (OSTI), ottobre 1988. http://dx.doi.org/10.2172/7074992.

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Birchenall, A. K. RTF glovebox stripper regeneration development. Office of Scientific and Technical Information (OSTI), ottobre 1992. http://dx.doi.org/10.2172/6949898.

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Yoshimura, Y., e E. Furimsky. Oxidative regeneration of hydrotreating catalysts. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1985. http://dx.doi.org/10.4095/302612.

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Mehta, Samir, e Kurt Hankenson. Notch Signaling in Bone Regeneration. Fort Belvoir, VA: Defense Technical Information Center, ottobre 2011. http://dx.doi.org/10.21236/ada564010.

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Birchenall, A. K. RTF glovebox stripper regeneration development. Office of Scientific and Technical Information (OSTI), ottobre 1992. http://dx.doi.org/10.2172/10131962.

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Gerber, Mark A., John G. Frye, Lawrence E. Bowman, John L. Fulton, Laura J. Silva e Chien M. Wai. Regeneration of Hydrotreating and FCC Catalysts. Office of Scientific and Technical Information (OSTI), settembre 1999. http://dx.doi.org/10.2172/15001475.

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