Tesi sul tema "Pyruvate"
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Debebe, Tewodros, Monika Krüger, Klaus Huse, Johannes Kacza, Katja Mühlberg, Brigitte König e Gerd Birkenmeier. "Ethyl pyruvate". Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-212525.
Testo completoBlalock, LeeAnn Talarico. "Expression of pyruvate decarboxylase in a Gram positive host Sarcina ventriculi pyruvate decarboxylase versus other known pyruvate decarboxylases /". [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0002366.
Testo completoWalker, Dianne. "Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335572.
Testo completoWexler, Isaiah David. "Disorders of pyruvate metabolism". Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1057937741.
Testo completoPeng, YI. "Pyruvate formate lyase and pyruvate formate lyase activating enzyme spectroscopic characteristics, interaction and mechanism /". Diss., Connect to online resource - MSU authorized users, 2008.
Cerca il testo completoJohnson, Sam. "Insulin regulation of pyruvate dehydrogenase". Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390644.
Testo completoBurthier, Jean Michel. "Les déficits en pyruvate déshydrogénase". Paris 5, 1990. http://www.theses.fr/1990PA05P176.
Testo completoCassady, Alan Ian. "Pyruvate carboxylase : a molecular biological study /". Title page, contents and summary only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phc343.pdf.
Testo completoChen, Yiyuan. "Regulation studies on human pyruvate kinases". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33175.
Testo completoRobinson, Andrew James Cave. "Pyruvate kinase & glycolysis in potato". Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335799.
Testo completoHildyard, John Carl Westgarth. "Identification of the mitochondrial pyruvate carrier". Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410146.
Testo completoBurnett, Paul. "Intramitochondrial Ca'2'+ and pyruvate dehydrogenase". Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389169.
Testo completoCheung, Wing Yee. "A yeast pyruvate decarboxylase regulatory gene". Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37659.
Testo completoNaik, Sharon S. "Regulation of the pyruvate dehydrogenase complex". Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1062509957.
Testo completoJitrapakdee, Sarawut. "Characterisation of the pyruvate carboxylase gene and studies on the regulation of its expression in rat /". Title page, contents and summaryn only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phj6117.pdf.
Testo completoWorku, Netsanet, August Stich, Arwid Daugschies, Iris Wenzel, Randy Kurz, Rene Thieme, Susanne Kurz e Gerd Birkenmeier. "Ethyl pyruvate emerges as a safe and fast acting agent against Trypanosoma brucei by targeting pyruvate kinase activity". Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-179599.
Testo completoKhew-Goodall, Yee Sim. "Pyruvate carboxylase: its interactions with acetyl CoA /". Title page, table of contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phk454.pdf.
Testo completoMistry, Sharad C. "Longer term regulation of pyruvate dehydrogenase kinase". Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335116.
Testo completoRidout, Cheryl Kathleen. "Splicing mutations in pyruvate dehydrogenase subunit genes". Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526109.
Testo completoLovell, Simon Christopher. "Structural studies of Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337172.
Testo completoDunford, Robin. "Pyruvate kinase and glycolytic control in potatoes". Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259704.
Testo completoMitchell, Rosie. "The regulation of human M2 pyruvate kinase". Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/21690.
Testo completoPotter, Simon. "Evaluation of pyruvate kinase as a potential phylogenetic marker : studies on the pyruvate kinase of the archaebacterium Thermoplasma acidophilum". Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/20117.
Testo completoSeyda, Agnieszka. "Pyruvate dehydrogenase complex, correlation between structure and function". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ58921.pdf.
Testo completoZhong, Wenhe. "Biochemical and structural studies on trypanosomatid pyruvate kinases". Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/7725.
Testo completoSmolle, Michaela. "Molecular architecture of the human pyruvate dehydrogenase complex". Thesis, University of Glasgow, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439249.
Testo completoJones, Bethan Sian. "Regulation of pyruvate dehydrogenase complex by reversible phosphorylation". Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315644.
Testo completoMullick, Abdul. "Engineering the cooperativity of Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388329.
Testo completoScotney, Pierre David. "The catalytic mechanism of Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266959.
Testo completoWilliams, K. P. "Studies on pyruvate : ferredoxin oxidoreductase from Trichomonas vaginalis". Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234978.
Testo completoAl-Amodi, Hiba Saeed Ahmed Bagader. "Immunological and biosynthetic studies of the human pyruvate dehydrogenase complex". Connect to e-thesis, 2007. http://theses.gla.ac.uk/139/.
Testo completoPh.D. thesis submitted to the Division of Biochemistry & Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, 2007. Includes bibliographical references. Print version also available.
Brown, Audrey Elaine. "Constructing a recombinant model of the human pyruvate dehydrogenase complex". Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248119.
Testo completoBowker-Kinley, Melissa M. "Pyruvate dehydrogenase kinase Kinetics, site-directed mutagenesis, and regulation /". [Bloomington, Ind.] : Indiana University, 2005. http://wwwlib.umi.com/dissertations/fullcit/3183930.
Testo completoSource: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3690. Chair: Robert A. Harris. Title from dissertation home page (viewed Oct. 5, 2006).
Yazdanpanah, Mehrdad. "Pyruvate improves myocardial functional recovery after ischemia and reperfusion". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0028/MQ34078.pdf.
Testo completoHan, Hongmei. "Molecular characterization of pyruvate ferredoxin oxidoreductase from Helicobacter pylori". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ36459.pdf.
Testo completoHu, Liangyan. "Characterization of human pyruvate dehydrogenase kinase isoform 2 (PDHK2". Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/856.
Testo completoGao, Xueliang. "Nuclear Pyruvate Kinase M2 Functional Study in Cancer Cells". Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/biology_diss/89.
Testo completoPulido-Cejudo, Gabriel. "Chemical and biological properties of iron-pyruvate-transferrin complexes". Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74529.
Testo completoDenyer, G. "Regulation of hepatic pyruvate dehydrogenase complex by reversible phosphorylation". Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233529.
Testo completoDay, S. E. "Detection of tumour treatment response using hyperpolarized 13C pyruvate". Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598434.
Testo completoAbayomi, Louise Anike. "Disposable pyruvate biosensors for routine assessment of onion flavour". Thesis, Cranfield University, 2007. http://dspace.lib.cranfield.ac.uk/handle/1826/5663.
Testo completoStewart, Melanie Ann. "Fatty acids and the regulation of pyruvate dehydrogenase interconversion". Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:d05910c0-f7a1-4363-ac2c-a9a1eb857964.
Testo completoWard, Jason David. "Targeting, assembly and regulation of the pyruvate dehydrogenase complex". Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264108.
Testo completoDave, Emma. "The physiology of the Escherichia coli pyruvate dehydrogenase complex". Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364242.
Testo completoCanas, Ana. "Acetoin production from pyruvate in Leuconostoc mesenteroides NCDO 518". Thesis, University of Reading, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319244.
Testo completoPoole, Robert C. "Transport of lactate and pyruvate across mammalian plasma membranes". Thesis, University of Bristol, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330043.
Testo completoAllen, Mark Devin. "Interaction of protein domains in pyruvate dehdrogenase multienzyme complex". Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242899.
Testo completoTulloch, Lindsay B. "Pyruvate kinase from Leishmania mexicana as a chemotherapeutic target". Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/14592.
Testo completoMcNally, Teresa. "Studies on the allosteric control of yeast pyruvate kinase". Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/19133.
Testo completoSeyran, Sevde Berfin. "Metabolic functions of the multifunctional protein E4F1 in skin homeostasis". Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT024/document.
Testo completoThe multifunctional protein E4F1 is an essential regulator of normal skin homeostasis. During my Phd, I demonstrated that E4f1 inactivation in adult skin results in stem cell autonomous defects causing exhaustion of the epidermal stem cell (ESC) pool. At the molecular level, I identified E4F1 as a new regulator of the pyruvate dehydrogenase complex (PDC) in keratinocytes, an essential mitochondrial complex that converts pyruvate into Acetyl-CoEnzyme A. Using genetically engineered mouse models, I showed that E4F1-mediated control of PDH activity is required to maintain normal skin homeostasis. Consistently, E4F1 deficiency in basal keratinocytes resulted in deregulated expression of dihydrolipoamide acetlytransferase (Dlat), a gene encoding the E2 subunit of the PDC, and impaired PDH activity. The metabolic reprogramming of E4f1 KO keratinocytes associated with the redirection of the glycolytic flux towards lactate production and increased lactate secretion in their microenvironment, leading to enhanced activity of extra-cellular-matrix remodelling proteases Finally, these defects ended in alterations of the basement membrane, ESC mislocalization and the exhaustion of the ESC pool. In the second part of my thesis, I have evaluated the role of E4F1-mediated control of the PDC in melanocytes and showed that the metabolic activities of E4F1 are important for melanocyte function. Consistently, mice with E4f1-deficient melanocytes exhibited hair graying and skin pigmentation defects. Altogether, my data demonstrate the importance of E4f1-mediated control of pyruvate metabolism for normal skin homeostasis