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Letteratura scientifica selezionata sul tema "PSMD"

Autore: Grafiati

Pubblicato: 5 aprile 2025

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Articoli di riviste sul tema "PSMD"

Salah Fararjeh, AbdulFattah, Ali Al-Khader, Malak Al-Saleem e Rinad Abu Qauod. "The Prognostic Significance of Proteasome 26S Subunit, Non-ATPase (PSMD) Genes for Bladder Urothelial Carcinoma Patients". Cancer Informatics 20 (gennaio 2021): 117693512110676. http://dx.doi.org/10.1177/11769351211067692.

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Proteasome a highly sophisticated systems that alter protein structure and function. Proteasome 26S Subunit, Non-ATPase (PSMD) genes have been implicated in several types of malignancies. This is the first study to look at how proteasomal subunits are expressed in patients with bladder urothelial carcinoma (BLCA). BLCA was used to evaluate the predictive value of PSMD genes (PSMD1 to PSMD12) in relation to clinicopathological characteristics. PSMD genes’ expression patterns at the mRNA level were analyzed using a variety of bioinformatics methods, including gene expression profile integrative analysis (GEPIA), Oncomine, TCGA, and Gene expression Omnibus (GEO) databases. The GEPIA and TCGA dataset survival plot functions were used to assess the prognostic significance of PSMD genes. PSMD2, PSMD3, PSMD4, PSMD8, and PSMD11 genes were significantly overexpressed in BLCA compared with normal bladder tissues. PSMD2 and PSMD8 were significantly overexpressed in BLCA more than other types of cancer. High level of PSMD2 and PSMD8 predicted shorter overall (OS) and progression free survival (PFS) in BLCA patients. High level of PSMD2 was significantly associated with elder age ( P < .001), female gender ( P = .014), tumor grade ( P < .001), and metastasis ( P = .003). PSMD2 has been shown to be an independent predictor for OS in BLCA patients based on univariate and multivariate analysis ( P < .001). Overall, according to this study, PSMD2 and PSMD8 could be served as a prognostic biomarker for BLCA patients.

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Jacelon, Cynthia, Maral Torrisan e Sarah Fiske. "OLDER DYADS USING A WEARABLE PERSONAL SLEEP MONITORING DEVICE FOR SLEEP SELF-MANAGEMENT". Innovation in Aging 6, Supplement_1 (1 novembre 2022): 692–93. http://dx.doi.org/10.1093/geroni/igac059.2539.

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Abstract Normally occurring changes in sleep patterns can affect behavior, safety, and function in older individuals. In addition, altered sleep of one partner can affect the functioning of the other. We tested a novel intervention using an off the shelf, wrist-worn actigraph as a personal sleep monitoring device (PSMD) with dyads comprised of individuals who were 70 years old or older, and slept in the same house. Aims included: 1) Establish the feasibility of sleep self-monitoring using PSMDs, as a self-management strategy. 2) Establish the feasibility of PSMD data sharing among members of the dyad to improve sleep self-management and improve sleep quality; and 3) Evaluate the usability of PSMDs and data sharing for dyads of older individuals. Over the course of a five-week trial, we used a mixed methods approach. Data were comprised of daily sleep diaries, data from the PSMD, weekly questionnaires regarding sleep patterns and function, and qualitative interviews focused on sleep, self-management within the dyad, and the usability of the PSMD. Data were analyzed using qualitative or statistical methods. The use of the PSMD increased awareness of sleep patterns at the individual and dyadic levels, but the limitations of the PSMD were frustrating. Participants valued having a graphic image of how their daily activities affected their sleep patterns. The dyadic approach was effective in improving sleep patterns for older individuals, and using over the counter activity monitoring devices provide a relatively inexpensive way to assist older adults to improve their sleep self-management.

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Septiansyah, Dhimas Anggi, Emi Wuri Wuryaningsih e Fitrio Deviantony. "Relationship between National Health Insurance Ownership and Compliance with Access to Health Services for Patients with Severe Mental Disorders (PSMD) “Pasung” in Blitar Regency, Indonesia". Journal of Community Empowerment for Health 6, n. 3 (8 dicembre 2023): 128. http://dx.doi.org/10.22146/jcoemph.66649.

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Patients with Severe Mental Disorders (PSMD) "Pasung" require long-term care, which causes a financial burden on the family. The Indonesian government has guaranteed funding for the treatment. However, there are still PSMDs who do not make regular visits to health services. This study aimed to describe the Relationship between National Health Insurance Ownership and Compliance with Access to Health Services for PSMDin Blitar Regency, Indonesia. This study used an analytic observational design with a retrospective cohort study approach. Total sampling techniques selected 50 PSMD "pasung" recorded health insurance and several visits to primary health services. The data was obtained from the primary health services reporting records from January to March 2020. This study used the biserial point correlation (CI: 99%) test for analyzing data. This study has ethical clearance approval. The results showed that there was a positive relationship between ownership of NHI and compliance with access to health services (t-obs (3,491) ≥ critical (2,678); p-value = 0,001; r-bis = 0,450; α = 0,01). Indonesia has guaranteed the cost of PSMD treatment with shackles, but patients and families who use these facilities are not optimal. In conclusion, national health insurance ownership is related to compliance with access to health services for PSMD "Pasung". Health agencies can pay attention to policy-making for enhancing access to health services of PSMD "Pasung".

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Lara, Joshua J., Alfonso E. Bencomo-Alvarez, Mayra A. Gonzalez, Idaly M. Olivas, James E. Young, Jose L. Lopez, Vanessa V. Velazquez et al. "19S Proteasome Subunits as Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML)". International Journal of Molecular Sciences 23, n. 23 (23 novembre 2022): 14586. http://dx.doi.org/10.3390/ijms232314586.

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26S proteasome non-ATPase subunits 1 (PSMD1) and 3 (PSMD3) were recently identified as prognostic biomarkers and potential therapeutic targets in chronic myeloid leukemia (CML) and multiple solid tumors. In the present study, we analyzed the expression of 19S proteasome subunits in acute myeloid leukemia (AML) patients with mutations in the FMS-like tyrosine kinase 3 (FLT3) gene and assessed their impact on overall survival (OS). High levels of PSMD3 but not PSMD1 expression correlated with a worse OS in FLT3-mutated AML. Consistent with an oncogenic role for PSMD3 in AML, shRNA-mediated PSMD3 knockdown impaired colony formation of FLT3+ AML cell lines, which correlated with increased OS in xenograft models. While PSMD3 regulated nuclear factor-kappa B (NF-κB) transcriptional activity in CML, we did not observe similar effects in FLT3+ AML cells. Rather, proteomics analyses suggested a role for PSMD3 in neutrophil degranulation and energy metabolism. Finally, we identified additional PSMD subunits that are upregulated in AML patients with mutated versus wild-type FLT3, which correlated with worse outcomes. These findings suggest that different components of the 19S regulatory complex of the 26S proteasome can have indications for OS and may serve as prognostic biomarkers in AML and other types of cancers.

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Ramdas, Premdass, Ammu Kutty Radhakrishnan, Asmahani Azira Abdu Sani, Mangala Kumari, Jeya Seela Anandha Rao e Puteri Shafinaz Abdul-Rahman. "Advancing the Role of Gamma-Tocotrienol as Proteasomes Inhibitor: A Quantitative Proteomic Analysis of MDA-MB-231 Human Breast Cancer Cells". Biomolecules 10, n. 1 (21 dicembre 2019): 19. http://dx.doi.org/10.3390/biom10010019.

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Tocotrienol, an analogue of vitamin E has been known for its numerous health benefits and anti-cancer effects. Of the four isoforms of tocotrienols, gamma-tocotrienol (γT3) has been frequently reported for their superior anti-tumorigenic activity in both in vitro and in vivo studies, when compared to its counterparts. In this study, the effect of γT3 treatment in the cytoplasmic and nuclear fraction of MDA-MB-231 human breast cancer cells were assessed using the label-free quantitative proteomics analysis. The cytoplasmic proteome results revealed the ability of γT3 to inhibit a group of proteasome proteins such as PSMA, PSMB, PSMD, and PSME. The inhibition of proteasome proteins is known to induce apoptosis in cancer cells. As such, the findings from this study suggest γT3 as a potential proteasome inhibitor that can overcome deficiencies in growth-inhibitory or pro-apoptotic molecules in breast cancer cells. The nuclear proteome results revealed the involvement of important nuclear protein complexes which hardwire the anti-tumorigenesis mechanism in breast cancer following γT3 treatment. In conclusion, this study uncovered the advancing roles of γT3 as potential proteasomes inhibitor that can be used for the treatment of breast cancer.

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Jochems, Angela C. C., Susana Muñoz Maniega, Una Clancy, Daniela Jaime Garcia, Carmen Arteaga, Will Hewins, Rachel Penman et al. "Associations of Peak-Width Skeletonized Mean Diffusivity and Post-Stroke Cognition". Life 12, n. 9 (31 agosto 2022): 1362. http://dx.doi.org/10.3390/life12091362.

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Post-stroke cognitive impairment is common and can have major impact on life after stroke. Peak-width of Skeletonized Mean Diffusivity (PSMD) is a diffusion imaging marker of white matter microstructure and is also associated with cognition. Here, we examined associations between PSMD and post-stroke global cognition in an ongoing study of mild ischemic stroke patients. We studied cross-sectional associations between PSMD and cognition at both 3-months (N = 229) and 1-year (N = 173) post-stroke, adjusted for premorbid IQ, sex, age, stroke severity and disability, as well as the association between baseline PSMD and 1-year cognition. At baseline, (mean age = 65.9 years (SD = 11.1); 34% female), lower Montreal Cognitive Assessment (MoCA) scores were associated with older age, lower premorbid IQ and higher stroke severity, but not with PSMD (βstandardized = −0.116, 95% CI −0.241, 0.009; p = 0.069). At 1-year, premorbid IQ, older age, higher stroke severity and higher PSMD (βstandardized = −0.301, 95% CI −0.434, −0.168; p < 0.001) were associated with lower MoCA. Higher baseline PSMD was associated with lower 1-year MoCA (βstandardized = −0.182, 95% CI −0.308, −0.056; p = 0.005). PSMD becomes more associated with global cognition at 1-year post-stroke, possibly once acute effects have settled. Additionally, PSMD in the subacute phase after a mild stroke could help predict long-term cognitive impairment.

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Yadav, Anurag, Kusum Yadav e Anupam Vashistha. "Phosphate solubilizing activity of Pseudomonas fluorescens PSM1 isolated from wheat rhizosphere". Journal of Applied and Natural Science 8, n. 1 (1 marzo 2016): 93–96. http://dx.doi.org/10.31018/jans.v8i1.754.

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A study was designed to screen and analyze the efficient phosphate solubilizing bacteria (PSBs) from wheat rhizosphere. Five biovars of Pseudomonas fluorescens (PSM1, PSM2, PSM3, PSM4 and PSM5) were isolated from wheat rhizosphere and Bacillus megaterium MTCC 8755 procured from microbial type culture collection (MTCC) Chandigarh, India. The P. fluorescens biovar PSM1 was observed to be most efficient phosphate solubilizer. Inoculation of P. fluorescens PSM1 and B. megaterium MTCC 8755, alone and in combination, caused the highest phosphate solubilization at pH 5. At this pH, maximum phosphate solubilization was observed with B. megaterium MTCC 8755 inoculation (8.2 mg mL-1) on sixth day of incubation with P. fluorescens PSM1 (8 mg mL-1) on seventh day of incubation and with dual bacterial treatment (10.5 mg mL-1) on the fourth day of incubation. A correlation coefficient of linear regression equation of phosphate solubilization with pH indicated that pH value of the medium was directly correlated with tricalcium phosphate solubilization. The study will help in choosing soil pH specific PSB inoculant for optimizing plant growth.

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Zulfiqar, Usman, Muhammad Ahmad, Mohammad Valipour, Muhammad Ishfaq, Muhammad Faisal Maqsood, Rashid Iqbal, Muhammad Fraz Ali, Rana Roy e Ayman El Sabagh. "Evaluating Optimum Limited Irrigation and Integrated Nutrient Management Strategies for Wheat Growth, Yield and Quality". Hydrology 10, n. 3 (25 febbraio 2023): 56. http://dx.doi.org/10.3390/hydrology10030056.

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Agricultural productivity is significantly influenced by the restricted availability of irrigation water and poor soil health. To assess the influence of different potential soil moisture deficit (PSMD) regimes and integrated nutrient levels on the growth, yield, and quality of wheat, an experiment was carried out at the research area of the University of Agriculture, Faisalabad. The experiment includes three levels of PSMD (I1: 25 mm PSMD, I2: 50 mm PSMD, and I3: 75 mm PSMD) and four integrated nutrition levels (N1: 50% organic manure + 50% Inorganic NPK, N2: 75% organic manure + 25% inorganic NPK, N3: 100% application of organic manure, and N4: 100% application of inorganic NPK). Results of the experiment revealed that maximum grain yield (4.78 t ha−1) was obtained as a result of irrigation at 50 mm PSMD with the combined use of organic and inorganic sources in equal proportions. In contrast, the minimum yield was observed at I3: 75 mm PSMD with 100% application of organic manure. The highest plant height (99.11 cm), fertile tillers (284.4), 1000-grain weight (44.48 g), biological yield (14.82 t ha−1), radiation use efficiency for grain yield (RUEGY) (5.71 g MJ−1), and radiation use efficiency for total dry matter (RUETDM) (2.15 g MJ−1) were observed under N1: 50% organic manure with 50% inorganic NPK treatment. The highest value of these parameters was also observed in I2 (50 mm PSMD). The results of this study can be extended to arid and semi-arid regions, where deficit irrigation is a key strategy to address water crises and to meet sustainable development goals.

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Algristian, Hafid, Fifi Khoirul Fitriyah, Abdul Hakim Zakkiy Fasya, Difran Nobel Bistara, Rahmadaniar Aditya Putri e Khadijah Khairul Bariyah. "PATIENT-SELECTION PROGRAM TRAINING FOR MENTAL HEALTH CADRES IN DEVELOPING INDEPENDENT BUSINESS FOR THE FAMILY". Community Service Journal of Indonesia 6, n. 1 (4 giugno 2024): 26–34. http://dx.doi.org/10.36720/csji.v6i1.630.

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People with severe mental disorder (PSMD; Orang Dengan Gangguan Jiwa, ODGJ) are a vulnerable group of people who experience loss of their rights to life because of their mental limitations, namely the right to work and earn an income independently. In previous activities, there was an opportunity for PSMD to recover through a series of training. To achieve recovery, it is necessary to hold a patient selection program so that patients who take part in the training series are not in the acute phase. Mental health cadres who are close to the community have a big role in determining which PSMD will then take part in entrepreneurship training activities. Therefore, mental health cadres need to deepen their insight into mental disorders and increase their empowerment in patient selection programs for PSMD. This activity aims to increase the understanding of mental health cadres regarding mental disorders and increase their empowerment in implementing patient selection programs for PSMD. The method used was by conducting outreach to mental health cadres regarding the topic of mental disorders as well as providing patient selection program training to mental health cadres. Before counseling and training, a 10-minute pre-test was conducted for the participants, then continued with an outreach and training session as well as questions and answers and discussions for approximately 60 minutes, and at the end a 10-minute post-test was carried out. The results showed an increase in pre-test and post-test data on the topic of mental disorders as well as an increase in empowerment by mental health cadre participants in carrying out patient selection programs. Community service activities regarding patient selection program training for mental health cadres in developing independent businesses for PSMD families in the Gresik district have provided improvements to mental health cadres, namely in the form of increased insight regarding mental disorders and increased empowerment in carrying out patient selection programs for PSMD.

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LeBlanc, Raeann G., Maral Torossian, Paige Czarnecki, Rebecca Spencer, Cynthia Jacelon e Jenna Marquard. "PERSONAL SELF-MONITORING DEVICES TO IMPROVE SLEEP AMONG OLDER PEOPLE: A FEASIBILITY STUDY". Innovation in Aging 3, Supplement_1 (novembre 2019): S919. http://dx.doi.org/10.1093/geroni/igz038.3348.

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Abstract Chronic sleep disturbances reduce physical and mental health and affect over 8 million people age 65 years and older in the United States. There is evidence that use of a wearable Personal Self-Monitoring Device (PSMD) may improve sleep self-management in young adult populations. Feasibility of PSMD use for older individuals has not been explored and was the goal of this study. Persons age 65 years and over with self-reported sleep disturbances were recruited in a local community and were asked to wear a commercial PSMD for a 4-week period. To assess whether such an intervention may be feasible, outcomes included consent rate, study completion rate, data download interpretation, identification of a sleep self-management goal, improved knowledge about sleep, and improved sleep. Twenty-six persons (12 males and 14 females) were recruited over 3 months, out of a total of 33 expressing interest. Mean age=72, SD=4.99. Ninety-two percent of participants completed the study and reported improved awareness of sleep patterns and identified a sleep goal. Total sleep time was M=7 hours 14 minutes, SD=40 minutes; total restful sleep time was M=4 hours 33 minutes, SD=1 hour 22 minutes. In conclusion, sleep self-management with the use of a PSMD is feasible and of interest among persons in the young-old age category (65-74 years). There is potential for the use of PSMD among older people with the goal of improved sleep self-management. Future studies for sleep health self-management and interventions using personal sleep monitoring are recommended.

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Più fonti

Tesi sul tema "PSMD"

Saba, Yasaman. "Déterminants génétiques des marqueurs IRM du vieillissement vasculaire cérébral". Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0466.

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Au cours des dernières années l’espérance de vie accrue a conduit à une augmentation majeure du nombre de nouveaux patients atteints de maladies neurologiques communes, notamment AVC et démence. Des preuves croissantes suggèrent que des déterminants précoces tout au long de la vie, y compris des facteurs génétiques, jouent un rôle crucial dans l'apparition de ces maladies. La maladie des petits vaisseaux cérébraux (MPVC) est une cause majeure d'AVC, de déclin cognitif et de démence. La MPVC est le plus souvent « occulte », détectable en imagerie cérébrale en l'absence de manifestations cliniques. Les marqueurs en IRM cérébrale de la MPVC, qui peuvent être mesurés de manière non invasive dans de grandes cohortes, peuvent fournir des informations cruciales sur les mécanismes physiopathologiques sous-tendant AVC et démences. Les hypersignaux de la substance blanche (HSB), les lacunes, les microhémorragies cérébrales et les espaces périvasculaires sont les marqueurs de MPVC les plus souvent étudiés en IRM, tandis que l'imagerie par tenseur de diffusion (DTI) offre de nouvelles opportunités pour explorer la susceptibilité à la MPVC tout au long de la vie. Déchiffrer ces facteurs de risque génétiques de la MPVC, y compris à des stades précoces de la vie, est un outil puissant pour comprendre les mécanismes moléculaires menant à cette maladie. Dans cette thèse, nous avons exploré les déterminants génétiques des marqueurs d'IRM de la MPVC dans la population générale tout au long de la vie, en réalisant de grandes métaanalyses collaboratives d'études d'association génétiques pangénomiques (GWAS), incluant jusqu'à 58,403 participants de la population générale. Tout d'abord, nous avons réalisé une GWAS des HSB stratifiée sur la présence ou absence d'hypertension artérielle. Nos résultats apportent un nouvel éclairage sur les effets modificateurs de l'hypertension artérielle sur la susceptibilité génétique aux HSB. Deuxièmement, nous avons examiné les déterminants génétiques d'un nouveau marqueur en DTI, la « peak width of skeletonized mean diffusivity » (PSMD), en réalisant une première GWAS de PSMD, tout au long de la vie. Nous avons identifié 25 nouveaux loci associés à un PSMD plus élevé, avec une bonne corrélation de la taille d’effets entre des populations européennes et asiatiques. De plus, dans une étude d'association sur l'exome entier à partir de données de séquençage panexomique, des variants rares et la combinaison de variants rares avec perte de fonction ou de variants « singleton » dans 4 gènes différents étaient associés au PSMD. Un volume d’HSB déterminé génétiquement était associé significativement à un PSMD plus élevé non seulement à tous les âges de la vie adulte mais également chez l’enfant. Par ailleurs, les variants communs associés à un PSMD élevé étaient enrichis en gènes exprimés dans les cellules endothéliales cérébrales foetales, suggérant des effets développementaux. En conclusion, ce travail fournit de nouvelles informations sur la génomique des formes complexes de MPVC, tout au long de la vie, dans différents groupes ethniques, et en tenant compte de la présence d'hypertension artérielle, le facteur de risque le plus courant de MPVC. Ces résultats sont informatifs pour le développement de stratégies préventives et thérapeutiques pour la MPVC et ses complications, un enjeu majeur de santé publique
Over the last century, life expectancy has increased dramatically, contributing to a sharp increase in the number of patients with common neurological disease, especially stroke and dementia. Mounting evidence suggests that early life factors, including genetic factors, play a crucial role in the occurrence of such diseases. Cerebral small vessel disease (cSVD) is a major cause of stroke, cognitive decline and dementia. cSVD is most often covert, detectable on brain images in the absence of clinical manifestations. Brain magnetic resonance imaging (MRI) markers of cSVD, which can be measured non-invasively in large population, can provide crucial insights into the cause of late-life neurological diseases. White matter hyperintensities (WMH), lacunes, cerebral microbleeds, and perivascular spaces are the most commonly studied MRI-markers of cSVD, while diffusion tensor imaging (DTI) offers new opportunity to explore susceptibility to cSVD across the lifespan. Deciphering these genetic risk factors of cSVD, including in early life, is a powerful tool to decipher molecular mechanisms leading to this disease. In this thesis, we explored the genetic determinants of MRI-markers of cSVD in the general population across the lifespan, by conducting large collaborative meta-analyses of genome-wide association studies (GWAS) in up to 58,403 participants from the general population. First, we conducted a GWAS of WMH stratified on hypertension status. Our results shed new light into modifying effects of high blood pressure on genetic susceptibility to WMH. Second, we examined the genetic underpinnings of an emerging DTI marker, peak width of skeletonized mean diffusivity (PSMD), by conducting the first GWAS of PSMD, across the lifespan. We identified up to 25 novel genetic risk loci for PSMD, with good effect size correlation across European and East-Asian ancestries. Additionally, in a whole-exome association study (derived from whole exome sequencing), rare variants and burden of rare loss-of-function or singleton variants in 4 different genes were associated with PSMD. Genetically determined larger volume of WMH was associated with higher PSMD from early childhood to older age. Moreover, common PSMD risk loci were enriched in genes expressed in fetal brain endothelial cells. In conclusion, this work provides new insights into complex genomics of cSVD across the lifespan, across ancestries, and in interaction with hypertension, the most common risk factor of cSVD. These results are informative for the development of efficient preventive and therapeutic strategies for cSVD and its complications, a major public health challenge

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Nakahira, Yoichi. "Circadian Clock-Regulated Transcription of the psbD Light-Responsive Promoter (psbD LRP) in Wheat Chloroplasts". Kyoto University, 1998. http://hdl.handle.net/2433/182388.

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Kyoto University (京都大学)
0048
新制・課程博士
博士(人間・環境学)
甲第7534号
人博第48号
10||158(吉田南総合図書館)
新制||人||11(附属図書館)
UT51-98-W278
京都大学大学院人間・環境学研究科人間・環境学専攻
(主査)教授豊島喜則, 教授丸山圭蔵, 教授竹安邦夫, 教授藤堂剛
学位規則第4条第1項該当

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Pelikán, Leoš. "Průmyslový PSD regulátor". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219666.

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This master’s thesis deal with principles temperature measurement using resistive temperature sensor PT100 and algorithm design PSD controler. In Work is includ description problems temperature measurement and way evaluation by means of mikrokontroler, which by PWM output controls supplied heat power. Next is here described method realization controls device for heating electric furnace with setup via Ethernet.

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Arabgol, Raheleh. "MBBR Produced Solids: Particle Characteristics, Settling Behaviour and Investigation of Influencing Factors". Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/41919.

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The separation of solids from biological wastewater treatment is an important step in the treatment process, as it has a significant impact on effluent water quality. The moving bed biofilm reactor (MBBR) technology is a proven upgrade or replacement wastewater treatment system for carbon and nitrogen removal. However, a challenge of this technology is the characteristics of the effluent solids that results in their poor settlement; with settling being the common method of solids removal. The main objective of this research is to understand and expand the current knowledge on the settling characteristics of MBBR produced solids and the parameters that influence them. In particular, in this dissertation, the impacts are studied of carrier types, biofilm thickness restraint design of carriers, and varying carbonaceous loading rates on MBBR performance, biofilm morphology, biofilm thickness, biofilm mass, biofilm density, biofilm detachment rate, solids production, particle size distribution (PSD) and particle settling velocity distribution (PSVD). With this aim, three MBBR reactors housing three different carrier types were operated with varying loading rates. In order to investigate the effect of carrier geometrical properties on the MBBR system, the conventional, cylindrically-shaped, flat AnoxK™ K5 carrier with protected voids was compared to two newly-designed, saddle-shaped Z-carriers with the fully exposed surface area. Moreover, the AnoxK™ Z-200 carrier was compared to the AnoxK™ Z-400 carrier to evaluate the biofilm thickness restraint design of these carriers, where the Z-200 carrier is designed for greater biofilm thickness-restraint. The Z-200 carrier is designed to limit the biofilm thickness to the level of 200 µm as opposed to 400 µm for the Z-400 carrier. Finally, to investigate the effects of varying carbonaceous loading rates on system removal performance, biofilm characteristics and solids characteristics, further analyses were performed at three different loading rates of 1.5 to 2.5 and 6.0 g-sBOD/m2·d in steady-state conditions. The PSD and the PSVD analyses were combined to relate these two properties. A settling velocity distribution analytical method, the ViCAs, was applied in combination with microscopy imaging and micro-flow imaging to investigate the relation of PSD and settling behaviour of MBBR produced particles. The obtained results have indicated that the carrier type significantly impacted the MBBR performance, biofilm, and particle characteristics. As such, the K5 carrier MBBR system demonstrated a statistically significantly higher carbonaceous removal rate and efficiency (3.8 ± 0.3 g-sBOD/m2·d and 59.9 ± 3.0% sBOD removal), higher biofilm thickness (281.1 ± 8.7 μm), higher biofilm mass per carrier (43.9 ± 1.0 mg), lower biofilm density (65.0 ± 1.5 kg/m3), lower biofilm detachment rate (1.7 ± 0.7 g-TSS/ m2·d) and hence lower solids production (0.7 ± 0.3 g-TSS/d) compared to the two Z-carriers. The Z-carriers' different shape exposes the biofilm to additional shear stress, which could explain why the Z-carriers have thinner and denser biofilm, resulting in higher solids production and lower system performance in comparison with K5. Moreover, the carrier type was also observed to impact the particle characteristics significantly. PSD analysis demonstrated a higher percentage of small particles in the Z-carrier system effluent and hence a significantly lower solids settling efficiency. Therefore, the solids produced in the K5 reactor have shown enhanced settling behaviour, consisting of larger particles with faster settling velocities compared to Z-carriers. This dissertation also investigated the effects of restraint biofilm thickness on MBBR performance by comparing the Z-200 biofilm thickness-restraint carrier to the Z-400 carrier. No significant difference was observed in removal efficiency, biofilm morphology, biofilm density, biofilm detachment rate, and solids production between the Z-200 to the Z-400 carriers. The PSD and the PSVD analyses did not illustrate any significant difference in the particles’ settling behaviour for these two biofilm thickness restraint carriers, indicating that the biofilm thickness-restraint carrier design was not a controlling factor in the settling potential of MBBR produced solids. Finally, this research studied the effect of varying loading rates and demonstrated a positive, strong linear correlation between the measured sBOD loading rate and the removal rate, indicating first-order BOD removal kinetics. The biofilm thickness, biofilm density and biofilm mass decreased when the surface area loading rate (SALR) was increased from 2.5 to 6.0 g-sBOD/m2·d. The solids retention time (SRT) was also shown to decrease by increasing the SALR, where the lowest SRT (1.7 ± 0.1 days) was observed at the highest SALR, with the highest cell viability (81.8 ± 1.7%). Significantly higher biofilm detachment rate and yield were observed at SALR 2.5, with the thickest biofilm and a higher percentage of dead cells. Consequently, a higher fraction of larger and rapidly settling particles was observed at SALR of 2.5 g-sBOD/m2·d, which leads to a significantly better settling behaviour of the MBBR effluent solids. This study expands the current knowledge of MBBR-produced particle characteristics and settling behaviour. A comprehensive understanding of the MBBR system performance and the potential influencing factors on the MBBR produced solids, particle characteristics, and their settleability will lead to optimized MBBR design for future pilot- and full-scale applications of the MBBR.

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Grosof, Isaac (Isaac B. ). "Secure communication : CDS, PIR, PSM". Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/113150.

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Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2017.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 52-53).
Private Information Retrieval is the problem of querying two servers to nd a value in a database, while keeping the index private. We extend this problem to Generalized Wildcard PIR, where we instead query an aggregate of the entries whose indices match a pattern, called a generalized wildcard, which species what values each segment of the indices may take. We give a construction for this variant with similar communication to that of the best PIR protocols known. We study information theoretic models in cryptography, namely Private Information Retrieval, Conditional Disclosure of Secrets, and Private Simultaneous Messages. We give extensions of PIR and CDS in the area of generalized wildcards, and give constructions for those extensions. We discuss directions towards more ecient protocols, and raise open questions.
by Isaac Grosof.
M. Eng.

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Ribeiro, Ricardo Luiz Mendes. "PFL: do PDS ao PSD". Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/8/8131/tde-09092016-130237/.

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Este trabalho aborda a trajetória do PFL (Partido da Frente Liberal), desde a sua fundação em 1985 até 2010, quando já sob nova denominação DEM deixou de contar com seus três principais líderes: Jorge Bornhausen, Marco Maciel e Antônio Carlos Magalhães. A tese busca explicar as razões do sucesso do partido, até 2002, e de sua decadência a partir de então. Como principal hipótese, argumenta-se que a conexão com o governo federal foi a causa principal tanto do sucesso quanto da decadência da legenda, desencadeada pela passagem do PFL para a oposição após a vitória do Partido dos Trabalhadores na eleição presidencial de 2002. A análise da inserção do PFL no presidencialismo de coalizão e a narrativa da atuação dos três principais líderes do partido junto às altas esferas do governo federal foram os principais subsídios para a construção indutiva da comprovação da hipótese acima formulada.
This work addresses the path of the PFL (Partido da Frente Liberal), since its foundation in 1985 until 2010, when already under the new name - DEM - no longer count on its three main leaders: Jorge Bornhausen, Marco Maciel and Antonio Carlos Magalhães. The thesis seeks to explain the reasons for the party\'s success, until 2002, and its decline from then on. As the main hypothesis it is claimed that the connection to the federal government was the main cause of both, the success and the decline, triggered by the passage of the PFL to the opposition after the Workers Party (PT) victory in the presidential election of 2002. The analysis of PFL in the Brazilian coalitional presidentialism and the narrative of the three main important party leaders connections with high ranks of federal government provide the inductive proof of the above hypothesis.

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Woythal, Nadine [Verfasser]. "In vitro Validierung der in vivo PSMA-Expression in der 68Ga-PSMA-PET/CT beim primären Prostatakarzinom durch die Immunohistochemie / Nadine Woythal". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1179778480/34.

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Calais, Jérémie. "PSMA-targeted theranostics : from research to standard-of-care". Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPAST192.

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L'objectif de ce manuscrit de thèse Thèse de doctorat par Validation des Acquis de l'Expérience (VAE) est de mettre en évidence les principales études de recherche menées à UCLA qui ont conduit à l'implémentation clinique des technique théranostique ciblant le PSMA aux États-Unis. Le manuscrit est divisé en 2 parties : l'imagerie et la thérapie.Dans la première partie sont fournis les essais pivots d'efficacité diagnostique utilisés pour l'autorisation par la FDA du 68Ga-PSMA-11 (Article #1: Performance diagnostique de la TEP-PSMA pour la localisation de la récidive du cancer de la prostate: un essai clinique d'imagerie prospective multicentrique de phase 3 (n=635), PMID 30920593; Article #2: Performance diagnostique de la TEP-PSMA pour la détection des métastases ganglionnaires pelviennes avant prostatectomie radicale et curage ganglionnaire pelvien: un essai clinique d'imagerie prospective multicentrique de phase 3 (n=764), PMID 34529005), des études comparatives comparant la TEP-PSMA aux techniques d'imagerie standard (Article #3: TEP/TDM a la 18F-Fluciclovine et au 68Ga-PSMA-11 chez les patients présentant une récidive biochimique après prostatectomie avec un taux de PSA ≤2,0 ng/ml: un essai d'imagerie comparative prospectif monocentrique (n=50), PMID 31375469; Article #4: Comparaison de la TEP/TDM-PSMA et de l'IRMmp avec référence par histopathologie dans la détection, la localisation intra-prostatique et la détermination de l'extension locale du cancer primitif de la prostate: résultats dans une cohorte monocentrique d'un essai prospectif (n=74), PMID 34649942) et une étude montrant un impact significatif sur la prise en charge (Article #5: Cartographie par TEP/TDM-PSMA de la récidive biochimique du cancer de la prostate après prostatectomie radicale chez 270 patients avec un taux de PSA<1,0 ng/ml : Impact sur la planification de la radiothérapie de rattrapage (n=270), PMID 29123013) qui a conduit à un essai randomisé visant à montrer une amélioration des résultats cliniques grâce à la TEP-PSMA (Article #6: Essai randomisé prospectif de phase 3 de radiothérapie de rattrapage du cancer de la prostate guidée par TEP-PSMA [PSMA-SRT] (n=193), PMID 30616601; Article #7: Mise à jour de l'essai PSMA-SRT NCT03582774: un Essai randomisé prospectif de phase 3 de radiothérapie de rattrapage du cancer de la prostate guidée par TEP-PSMA (n=193), PMID 33386288).Dans la deuxième partie sont présentés les résultats du premier essai de phase 2 de la thérapie au 177Lu-PSMA aux USA qui a précédé l'essai VISION (Article #8 : Essai prospectif de phase 2 de radiothérapie moléculaire au 177Lu-PSMA-617 pour cancer de la prostate métastatique résistant à la castration (RESIST-PC): Résultats d'efficacité de la cohorte UCLA (n=43), PMID 34016732; Article #9: Tolérance et sécurité de la radiothérapie moléculaire au 177Lu-PSMA-617: résultats de l'essai prospectif multicentrique de phase 2 RESIST-PC NCT03042312 (n=64), PMID 34272322), des études rétrospectives multicentriques visant à affiner les critères de sélection TEP-PSMA (Article #10: Suivi des patients négatifs au PSMA par critères TEP-PSMA de l'essai VISION traités par 177Lu-PSMA: une analyse rétrospective multicentrique (n=301), PMID 35273096; Article #11: Ratio tumeur/glande salivaire par TEP-PSMA pour prédire la réponse à la thérapie par 177Lu-PSMA: une étude rétrospective multicentrique internationale (n=237), PMID 36997329; Article #12: Nomogrammes pour prédire les résultats après traitement au 177Lu-PSMA chez les patients atteints d'un cancer de la prostate métastatique résistant à la castration: une étude rétrospective internationale multicentrique (n=270), PMID 34246328) et une revue narrative des mécanismes de résistance à la thérapie au 177Lu-PSMA (Article #13: Prédicteurs de réponse et utilisation dans le monde réel de la radiothérapie moléculaire ciblée du cancer de la prostate: PSMA et au-delà. PMID 35609224)
The aim of this manuscript for PhD by Accreditation of Prior Learning is to highlight the key research studies conducted at UCLA which lead to the clinical implementation of PSMA-theranostics in the US. The manuscript is divided in 2 parts: imaging and Therapy.In the first part are provided the pivotal trials of diagnostic efficacy used for the FDA approval of 68Ga-PSMA-11 (Article #1: Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Multicenter Single-Arm Phase 3 Clinical Trial (n=635), WP Fendler at al. JAMA Oncol 2019 PMID 30920593; Article #2: Diagnostic Accuracy of 68Ga-PSMA-11 PET for Pelvic Nodal Metastasis Detection Prior to Radical Prostatectomy and Pelvic Lymph Node Dissection: A Multicenter Prospective Phase 3 Imaging Trial (n=764), TA Hope et al. JAMA Oncol 2021 PMID 34529005), head-to-head comparison trials comparing PSMA PET to standard of care imaging techniques (Article #3: 18F-Fluciclovine and 68Ga-PSMA-11 PET/CT in patients with biochemical recurrence after prostatectomy at PSA levels of ≤2.0ng/ml: a prospective single-center single-arm comparative imaging trial (n=50), J Calais et al. Lancet Oncol 2019 PMID 31375469; Article #4: Head-to-head comparison of 68Ga-PSMA-11 PET/CT and mpMRI with histopathology gold-standard in the detection, intra-prostatic localization and local extension of primary prostate cancer: results from a prospective single-center imaging trial (n=74), I Sonni et al. J Nucl Med 2022 PMID 34649942) and a study showing significant impact on management (Article #5: 68Ga-PSMA-11 PET/CT mapping of prostate cancer biochemical recurrence following radical prostatectomy in 270 patients with PSA<1.0ng/ml: Impact on Salvage Radiotherapy Planning (n=270), J Calais et al. J Nucl Med 2018 PMID 29123013) that lead to a randomized imaging trial powered for clinical outcome (Article #6: Randomized prospective phase 3 trial of 68Ga-PSMA-11 PET/CT molecular imaging for prostate cancer salvage radiotherapy planning [PSMA-SRT] (n=193), J Calais et al. BMC cancer 2019 PMID 30616601; Article #7: Update from PSMA-SRT Trial NCT03582774: A Randomized Phase 3 Imaging Trial of Prostate-specific Membrane Antigen Positron Emission Tomography for Salvage Radiation Therapy for Prostate Cancer Recurrence Powered for Clinical Outcome (n=193), J Calais et al. Eur Urol Focus PMID 33386288).In the second part are provided the results of the first phase 2 trial of 177Lu-PSMA therapy in the US that preceded the VISION trial (Article #8: Prospective phase 2 trial of PSMA-targeted molecular RadiothErapy with 177Lu-PSMA-617 for metastatic Castration-reSISTant Prostate Cancer (RESIST-PC): Efficacy results of the UCLA cohort (n=43), J Calais et al. J Nucl Med 2021 PMID 34016732; Article #9: Safety of PSMA-targeted molecular radioligand therapy with 177Lu-PSMA-617: results from the prospective multicenter phase 2 trial RESIST-PC NCT03042312 (n=64), J Calais et al. J Nucl Med 2021 PMID 34272322), multicenter retrospective studies aiming at refining the PSMA-PET selection criteria (Article #10: Outcome of patients with PSMA-PET/CT screen failure by VISION criteria and treated with 177Lu-PSMA therapy: a multicenter retrospective analysis (n=301), M Hotta et al. J Nucl Med 2022 PMID 35273096; Article #11: PSMA PET Tumor-to-Salivary Gland Ratio to Predict Response to 177Lu-PSMA Radioligand Therapy: An International Multicenter Retrospective Study (n=237), M Hotta et al. J Nucl Med 2023 PMID 36997329; Article #12: Nomograms to predict outcomes after 177Lu-PSMA therapy in men with metastatic castration-resistant prostate cancer: an international, multicenter, retrospective study (n=270), A Gafita et al. Lancet Oncol 2021 PMID 34246328) and a narrative review of the mechanisms of resistance to 177Lu-PSMA therapy (Article #13: Predictors and Real-World Use of Prostate-Specific Radioligand Therapy: PSMA and Beyond. A Gafita et al. Am Soc Clin Oncol Educ Book 2022 PMID 35609224)

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Zrůst, Vojtěch. "Implementation of Case Tool for PSD". Master's thesis, Vysoká škola ekonomická v Praze, 2016. http://www.nusl.cz/ntk/nusl-203866.

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The objective of this thesis is analysis, design and development of an application used for the Process-State Diagram (PSD). Purpose of this thesis is to make PSD tool available for as many users as possible in order to make it a standard tool for managers and analysts. The theoretical part analyzes the basic functionality that should be included in the first version of this app and the strategy and the method of implementation. An important part of the analysis is to compare the three types of applications: desktop, web and mobile; and their relevance to a given problem. The practical part includes the actual implementation and the necessary steps to deploy the application.

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Walker, Natalie. "PSMA-1-Doxorubicin Conjugates for Targeted Therapy of Prostate Cancer". Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1554496393458066.

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Libri sul tema "PSMD"

Ramos, Plínio de Abreu. O PSD mineiro. Belo Horizonte: Editora Itatiaia, 1993.

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Swanson, Eric T. Real wage cyclicality in the PSID. San Francisco]: Federal Reserve Bank of San Francisco, 2007.

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Law Society. Professional Standards and Development Directorate., a cura di. PSD professional standards bulletin. London: Law Society, Professional Standards & Development Directorate, 1995.

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Law Society. Professional Standards and Development Directorate., a cura di. PSD professional standards bulletin. London: Law Society, Professional Standards & Development Directorate, 1995.

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Law Society. Professional Standards and Development Directorate., a cura di. PSD professional standards bulletin. London: Law Society, Professional Standards & Development Directorate, 1996.

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Law Society. Professional Standards and Development Directorate., a cura di. PSD professional standards bulletin. London: Law Society, Professional Standards & Development Directorate, 1995.

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Darnell, Bryony. PSM2 ultimate A-to-Z tips book. [S.l.]: Future, 2003.

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Frederickson, Paul O. Normalized convergence rates for the PSMG method. Columbia, Md: Ames Research Center ; Research Institute for Advanced Computer Science, 1990.

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Manalvo, Nuno. PSD: A marca dos líderes. Lisboa: Notícias Editorial, 2001.

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Agency, Medical Devices, a cura di. Surgical diathermy: Olympus PSD-20. London: Medical Devices Agency, 1997.

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Capitoli di libri sul tema "PSMD"

Lopez, Jose Santamaria, A. Sai Vasanthi, Manisha Velaga, Akula Narendra Kumar, B. Kavya, Vinsha Shaik e S. Priyanka. "A Robust DIW Approach for UAV Image Transmission Using PSMD Encryption". In Swarm Intelligence, 196–212. Boca Raton: CRC Press, 2025. https://doi.org/10.1201/9781032693217-10.

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Donato, Dominique M., Steven K. Hanks, Kenneth A. Jacobson, M. P. Suresh Jayasekara, Zhan-Guo Gao, Francesca Deflorian, John Papaconstantinou et al. "PSMD7". In Encyclopedia of Signaling Molecules, 1492. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_101115.

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Pichler, Robert, Johannes Wolfsgruber, Ferdinando Calabria, Orazio Schillaci e Andreas Dunzinger. "68Ga-PSMA". In Radiopharmaceuticals, 211–25. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-27779-6_12.

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Pichler, Robert, Johannes Wolfsgruber, Ferdinando Calabria, Orazio Schillaci e Andreas Dunzinger. "68Ga-PSMA". In Radiopharmaceuticals, 219–33. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-54196-4_12.

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Altun Tuzcu, Sadiye. "68Ga PSMA PET/CT in Patients with Prostate Cancer". In The Radiology of Cancer, 498–504. Istanbul: Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359364.31.

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Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) is a new method of imaging prostate cancer that increases diagnostic accuracy in detecting reccurrent disease or metastasis and guiding therapy. Gallium-68 PSMA ligand PET/CT has increased sensitivity of detection of local recurrence or metastases at low PSA levels. PSMA PET/CT has also inceased sensitivity and specificity of detection of primary disease localisation and in detecting metastases at initial staging. In advence disease PSMA PET/CT may be able to evaluate response to chemotherapy or radionuclide therapies. This book chapter discusses the literatüre, clinical utility and our clinical experience of Ga-68 PSMA PET/CT imaging needed to improve clinical practice.

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Ballinger, James R. "68Ga-THP-PSMA". In PET Radiopharmaceuticals, 56–57. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-10271-4_26.

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Ballinger, James R. "18F-PSMA-1007". In PET Radiopharmaceuticals, 32–33. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-10271-4_16.

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Penn, Chad J., e James M. Bowen. "Characterization of PSMs". In Design and Construction of Phosphorus Removal Structures for Improving Water Quality, 105–28. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58658-8_5.

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Harisinghani, Mukesh G., Ranjodh Dhami, Aashna Karbhari, Riya Goyal, Soumyadeep Ghosh, Nabih Nakrour, Fatima Majeed et al. "False-Positive PSMA". In Abdominal and Pelvic Imaging Cases, 65–69. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-68233-9_15.

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Jadvar, Hossein. "Precision Oncology with PSMA-Targeted α-Particle Therapy of mCRPC". In Beyond Becquerel and Biology to Precision Radiomolecular Oncology: Festschrift in Honor of Richard P. Baum, 159–67. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-33533-4_15.

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AbstractProstate-specific membrane antigen (PSMA) has been firmly established as a clinically relevant biomarker in imaging and targeted radionuclide therapy (theranostics) of prostate cancer, particularly in the metastatic castrate-resistant state. Numerous investigations from around the world in both academic and pharma settings are focused on research and development of safe and effective PSMA-based theranostic agents. Encouraging results from retrospective studies using the β-particle emitting 177Lu-PSMA-617 radioligand therapy prompted prospective phase II and phase III randomized clinical trials with recently published favorable results of the VISION trial. While these pivotal investigations continue, there has also been major growing interest in the potential clinical utility of α-particle PSMA-targeted therapeutic agents. After a brief review of PSMA biology, imaging with positron emission tomography, and current experience with targeted β-particle (177Lu) therapy, this article summarizes the preclinical and early clinical studies that have evaluated the PSMA-targeted agents conjugated properly to α-particle radiolabels including 225Ac, 213Bi, 227Th, 212Pb, and 149Tb.

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Atti di convegni sul tema "PSMD"

Park, Jung-Kyu, e Gregory Washington. "Advanced Development of a Smart Material Design, Modeling, and Selection Tool". In ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2011. http://dx.doi.org/10.1115/smasis2011-5217.

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Smart materials have significantly varied properties and their various types are used broadly in many different engineering applications. It is important to develop tools which enable one to determine the best material for a particular application. In this research, system-level simulation models and collected material data are compiled in a GUI-based computer software called Polymers and Smart Materials Database (PSMD). This material selection tool encompasses material properties and material-level models as well as potential smart material applications. This type of compiled data can expedite the material selection process when designing smart material based systems by allowing one to choose the most effective material for the application. The software tool offers a wide variety of design and selection features. Material property and performance charts are provided to compare material properties and to choose the best material for optimal performance. The tool enables users to categorize material properties and create their own databases. This paper also highlights the modeling strategies being conducted in the area of elastomers and smart materials.

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Rubio, Andres J., Alfonso E. Bencomo-Alvarez, James E. Young, Vanessa V. Velazquez e Anna M. Eiring. "Abstract P150: PSMD1 and PSMD3 as putative targets for cancer therapy". In Abstracts: AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics; October 7-10, 2021. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1535-7163.targ-21-p150.

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Scott, Dane, Ted Lundquist e Tahir Malik. "Pulsed Spot Milling and Deposition to Enable Next Generation Circuit Edit Via Development". In ISTFA 2010. ASM International, 2010. http://dx.doi.org/10.31399/asm.cp.istfa2010p0426.

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Abstract Pulsed spot milling (PSM) and deposition (PSD) extends gallium ion beam technology for circuit edit. Similar to continuous spot mill, a single-point ion beam defines the basic milling profile, however, PSM utilizes a high-speed beam blanker to “pulse” the ion beam. This beam modulation replaces beam rastering by introducing a delay time which is fundamentally equivalent to refresh time during a typical scan pattern to enable and manage chemistry adsorption. Vias with a base diameter <50nm have been enabled by PSM in combination with advanced ion column designs, beam control parameters and endpointing techniques.

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Xu, Yanyu, Nianyi Li, Junru Wu, Jingyi Yu e Shenghua Gao. "Beyond Universal Saliency: Personalized Saliency Prediction with Multi-task CNN". In Twenty-Sixth International Joint Conference on Artificial Intelligence. California: International Joint Conferences on Artificial Intelligence Organization, 2017. http://dx.doi.org/10.24963/ijcai.2017/543.

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Saliency detection is a long standing problem in computer vision. Tremendous efforts have been focused on exploring a universal saliency model across users despite their differences in gender, race, age, etc. Yet recent psychology studies suggest that saliency is highly specific than universal: individuals exhibit heterogeneous gaze patterns when viewing an identical scene containing multiple salient objects. In this paper, we first show that such heterogeneity is common and critical for reliable saliency prediction. Our study also produces the first database of personalized saliency maps (PSMs). We model PSM based on universal saliency map (USM) shared by different participants and adopt a multi-task CNN framework to estimate the discrepancy between PSM and USM. Comprehensive experiments demonstrate that our new PSM model and prediction scheme are effective and reliable.

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Merkel, Petra. "PSD Technologies for Particle Physics". In PSD Technologies for Particle Physics. US DOE, 2024. http://dx.doi.org/10.2172/2282615.

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Diaconu, Florin, e Masato R. Nakamura. "Numerical Analysis of the Size and Shape of New York City Municipal Solid Waste (NYCMSW) and Residues for Combustion Chamber Design". In 2013 21st Annual North American Waste-to-Energy Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nawtec21-2736.

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The size and shape of New York City municipal solid waste (NYCMSW) and combustion residues (ashes) are numerically analyzed in order to investigate the size reduction of particles on the grate of a waste-to-energy (WTE) combustion chamber. It is also necessary for designing a new combustion chamber, due to the heterogeneous MSW particles. About 360 MSW particles for this study were sampled in the black bags collected in residential areas at five boroughs of New York City. Also about 210 ash particles from a WTE combustion chamber were sampled. Length, breadth, perimeter and area of each MSW and ash particle are measured by means of image analysis that is more accurate than sieve analysis. Based on the image analysis, the particle size distributions (PSiD) and particle shape distributions (PShD) of MSW and residues were created. The mean size of NYCMSW was found to be 12.8cm and standard deviation of the MSW PSiD to be 6.4. Also mean size and standard deviation of the ash PSiD to be 2.4cm and 0.5889, respectively. Also Three types of shape factors (aspect ratio, roundness and sphericity) are used for creating 3 PShDs (aspect-ratio distributions, roundness distributions and sphericity distributions). Based on the similarity of the particle shapes quantified as these shape factors, the particles of MSW and residues are divided into 9 clusters by means of cluster analysis. This cluster analysis showed categorized characteristics of particle shapes that can be used for predicting surface areas of particles and mobility of particles in MSW bed on the traveling grate, both of which are major parameters for simulating combustion process in WTE systems.

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Cuzzocrea, Alfredo. "PSBD 2014". In CIKM '14: 2014 ACM Conference on Information and Knowledge Management. New York, NY, USA: ACM, 2014. http://dx.doi.org/10.1145/2661829.2663544.

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Tabti, H., e L. J. Gelius. "Fresnel-Aperture PSDM". In 64th EAGE Conference & Exhibition. European Association of Geoscientists & Engineers, 2002. http://dx.doi.org/10.3997/2214-4609-pdb.5.a034.

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"PSBD 2017 Keynote". In 2017 IEEE 37th International Conference on Distributed Computing Systems Workshops (ICDCSW). IEEE, 2017. http://dx.doi.org/10.1109/icdcsw.2017.99.

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Hu, Ying, Ling Xu, Chunming Wang, Yongke Han, Huiwen Xie e Chao Wu. "PSDM-oriented processing workflow for topographic PSDM in thrust belts". In SEG Technical Program Expanded Abstracts 2013. Society of Exploration Geophysicists, 2013. http://dx.doi.org/10.1190/segam2013-0517.1.

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Rapporti di organizzazioni sul tema "PSMD"

Solomon, Jr, O M. PSD computations using Welch's method. [Power Spectral Density (PSD)]. Office of Scientific and Technical Information (OSTI), dicembre 1991. http://dx.doi.org/10.2172/5688766.

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Denmeade, Samuel R. PSMA-Activated Imaging Agents for Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, febbraio 2010. http://dx.doi.org/10.21236/ada538589.

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Iliev, Metodi, e Michael Browne. PSMC Upgrade Development Documentation and Functional Testing. Office of Scientific and Technical Information (OSTI), settembre 2021. http://dx.doi.org/10.2172/1822689.

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Maffioli, Alessandro, Carolyn Heinrich e Gonzalo Vázquez. A Primer for Applying Propensity-Score Matching. Inter-American Development Bank, agosto 2010. http://dx.doi.org/10.18235/0008567.

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This document provides a guide to the key aspects of implementing Propensity-Score Matching (PSM) methodology. It summarizes the basic conditions under which PSM can be used to estimate the impact of a program and the data required, presenting examples of PSM applications. It explains how the Conditional Independence Assumption, combined with the Overlap Condition, reduces selection bias when participation in a program is determined by observable characteristics. It also describes different matching algorithms and some tests to assess the quality of the matching.

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Duan, Liyang, Xiaoyu Li, Haiqin Rong, Haiju Sun, Yajun Zhang, Shipeng Song, Jianqiao Fang e Yongqiang Sun. Scalp acupuncture for Post-stroke depression: A protocol for a systematic review and meta-analysis of randomized controlled clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, aprile 2022. http://dx.doi.org/10.37766/inplasy2022.4.0059.

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Review question / Objective: To evaluate the efficacy and safety of scalp acupuncture for poststroke depression for the first time, and the results of this systematic review will be helpful for clinicians to use scalp acupuncture in the treatment of PSD. Condition being studied: Post-stroke depression (PSD) is one of the most common psychological sequelae of stroke, which is a state characterized by low mood and aversion to activity. It is one of the main obstacles in the process of stroke rehabilitation, which has a detrimental impact on functional recovery and quality of life and even increases mortality. Although the pathogenic factors of PSD are complex and diverse, it is now widely believed to involve complex interactions between neurobiological dysfunctions, psychosocial distress and biological factors. Despite increasing awareness and clinically based research on PSD, drugs to relieve and treat symptoms have made only limited gains. The use of antidepressants is accompanied by various unavoidable adverse effects, including headache, nausea, restlessness, and sexual dysfunction. A previous meta-analysis demonstrated that acupuncture can be safe and effective for the treatment of post-stroke depression. However, there is a lack of systematic reviews to evaluate the efficacy and safety of scalp acupuncture, which is a commonly used acupuncture modality in the treatment of PSD. Consequently, this study will assess the efficacy and safety of scalp acupuncture therapy for PSD compared to other treatments.

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Batcheller, Thomas Aquinas, Gary Michael Huestis e Steven Michael Bolton. Remote Laser Diffraction PSD Analyzer. Office of Scientific and Technical Information (OSTI), giugno 2000. http://dx.doi.org/10.2172/911470.

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Wurtz, R. E. FY19Q4 report for PSD project. Office of Scientific and Technical Information (OSTI), ottobre 2019. http://dx.doi.org/10.2172/1569659.

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T. A. Batcheller, G. M. Huestis e S. M. Bolton. Remote Laser Diffraction PSD Analyzer. Office of Scientific and Technical Information (OSTI), giugno 2000. http://dx.doi.org/10.2172/764162.

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Tiano, Elicia, e Melinda Sweany. Characterization of ORNL PSD ASIC. Office of Scientific and Technical Information (OSTI), gennaio 2024. http://dx.doi.org/10.2172/2430106.

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Chang, Yi-Hua, e Oliver A. McBryan. The PSMG Multiscale Method for an Anisotropic Problem. Fort Belvoir, VA: Defense Technical Information Center, dicembre 1992. http://dx.doi.org/10.21236/ada455040.

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