Articoli di riviste sul tema "Picropodophylline"
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Roulland, Emmanuel, Emmanuel Bertounesque, Christiane Huel e Claude Monneret. "Synthesis of picropodophyllin homolactone". Tetrahedron Letters 41, n. 35 (agosto 2000): 6769–73. http://dx.doi.org/10.1016/s0040-4039(00)01136-9.
Roulland, Emmanuel, Emmanuel Bertounesque, Christiane Huel e Claude Monneret. "ChemInform Abstract: Synthesis of Picropodophyllin Homolactone." ChemInform 31, n. 45 (7 novembre 2000): no. http://dx.doi.org/10.1002/chin.200045231.
Wen, Pu Hong. "Kinetic Investigation of Thermal Decomposition Reactions of Podophyllic Acid and Picropodophyllic Acid". Advanced Materials Research 391-392 (dicembre 2011): 1230–34. http://dx.doi.org/10.4028/www.scientific.net/amr.391-392.1230.
Guo, Hong Zhu, De An Guo, Xue Yan Fei, Ya Jun Cui e Jun Hua Zheng. "Biotransformation of Podophyllotoxin to Picropodophyllin by Microbes". Journal of Asian Natural Products Research 1, n. 2 (dicembre 1998): 99–102. http://dx.doi.org/10.1080/10286029808039850.
Ohshima-Hosoyama, Sachiko, Tohru Hosoyama, Laura D. Nelon e Charles Keller. "IGF-1 receptor inhibition by picropodophyllin in medulloblastoma". Biochemical and Biophysical Research Communications 399, n. 4 (settembre 2010): 727–32. http://dx.doi.org/10.1016/j.bbrc.2010.08.009.
Wu, Qi, Ai-Ling Tian, Guido Kroemer e Oliver Kepp. "Autophagy induction by IGF1R inhibition with picropodophyllin and linsitinib". Autophagy 17, n. 8 (10 giugno 2021): 2046–47. http://dx.doi.org/10.1080/15548627.2021.1936934.
Berkowitz, David B., Sungjo Choi e Jun-Ho Maeng. "Enzyme-Assisted Asymmetric Total Synthesis of (−)-Podophyllotoxin and (−)-Picropodophyllin". Journal of Organic Chemistry 65, n. 3 (febbraio 2000): 847–60. http://dx.doi.org/10.1021/jo991582+.
Pohmakotr, Manat, Taweechote Komutkul, Patoomratana Tuchinda, Samrarn Prabpai, Palangpon Kongsaeree e Vichai Reutrakul. "Syntheses of (±)-thuriferic acid ethyl ester, its analogues and (±)-picropodophyllone". Tetrahedron 61, n. 22 (maggio 2005): 5311–21. http://dx.doi.org/10.1016/j.tet.2005.03.069.
Pullin, Robert D. C., Jonathan D. Sellars e Patrick G. Steel. "Silenes in organic synthesis: a concise synthesis of (±)-epi-picropodophyllin". Organic & Biomolecular Chemistry 5, n. 19 (2007): 3201. http://dx.doi.org/10.1039/b710370k.
Colón, Eugenia, Farasat Zaman, Magnus Axelson, Olle Larsson, Christine Carlsson-Skwirut, Konstantin V. Svechnikov e Olle Söder. "Insulin-Like Growth Factor-I Is an Important Antiapoptotic Factor for Rat Leydig Cells during Postnatal Development". Endocrinology 148, n. 1 (1 gennaio 2007): 128–39. http://dx.doi.org/10.1210/en.2006-0835.
Zhao, Jing, Yajing Wang e Libiao Luan. "Star-Shaped Polycaprolactone-Polyethyleneglycol Copolymer Micelle-Like Nanoparticles for Picropodophyllin Delivery". Journal of Biomedical Nanotechnology 10, n. 8 (1 agosto 2014): 1627–34. http://dx.doi.org/10.1166/jbn.2014.1835.
Hashemi, Jamileh, Claire Worrall, Daiana Vasilcanu, Mårten Fryknäs, Luqman Sulaiman, Mohsen Karimi, Wen-Hui Weng et al. "Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)". PLoS ONE 6, n. 3 (14 marzo 2011): e14757. http://dx.doi.org/10.1371/journal.pone.0014757.
Lu, Xiaosheng, Ledan Wang, Jie Mei, Xin Wang, Xueqiong Zhu, Qiong Zhang e Jieqiang Lv. "Picropodophyllin inhibits epithelial ovarian cancer cells in vitro and in vivo". Biochemical and Biophysical Research Communications 435, n. 3 (giugno 2013): 385–90. http://dx.doi.org/10.1016/j.bbrc.2013.04.097.
Berkowitz, David B., Sungjo Choi e Jun-Ho Maeng. "ChemInform Abstract: Enzyme-Assisted Asymmetric Total Synthesis of (-)-Podophyllotoxin and (-)-Picropodophyllin." ChemInform 31, n. 23 (8 giugno 2010): no. http://dx.doi.org/10.1002/chin.200023243.
FENG, XIAOYING, EIMAN ALEEM, YINGBO LIN, MAGNUS AXELSON, OLLE LARSSON e THOMAS STRÖMBERG. "Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: Clinical implications". International Journal of Oncology 40, n. 4 (6 dicembre 2011): 1251–58. http://dx.doi.org/10.3892/ijo.2011.1281.
Wu, Xuping, Linda Sooman, Malin Wickström, Mårten Fryknäs, Christine Dyrager, Johan Lennartsson e Joachim Gullbo. "Alternative Cytotoxic Effects of the Postulated IGF-IR Inhibitor Picropodophyllin In Vitro". Molecular Cancer Therapeutics 12, n. 8 (22 maggio 2013): 1526–36. http://dx.doi.org/10.1158/1535-7163.mct-13-0091.
Yin, Shu-Cheng, Wei Guo e Ze-Zhang Tao. "Picropodophyllin inhibits tumor growth of human nasopharyngeal carcinoma in a mouse model". Biochemical and Biophysical Research Communications 439, n. 1 (settembre 2013): 1–5. http://dx.doi.org/10.1016/j.bbrc.2013.08.050.
Vitale, Maxime, Guillaume Prestat, David Lopes, David Madec, Claire Kammerer, Giovanni Poli e Leonard Girnita. "New Picropodophyllin Analogs via Palladium-Catalyzed Allylic Alkylation−Hiyama Cross-Coupling Sequences". Journal of Organic Chemistry 73, n. 15 (agosto 2008): 5795–805. http://dx.doi.org/10.1021/jo800707q.
Ogiku, Tsuyoshi, Shin-ichi Yoshida, Tooru Kuroda, Masami Takahashi, Hiroshi Ohmizu e Tameo Iwasaki. "Syntheses of Aryltetralin Lignans: Concise Syntheses of (±)-Isopodophyllotoxone, (±)-Picropodophyllone and Their Related Compounds". Bulletin of the Chemical Society of Japan 65, n. 12 (dicembre 1992): 3495–97. http://dx.doi.org/10.1246/bcsj.65.3495.
TOMIZAWA, MINORU, FUMINOBU SHINOZAKI, YASUFUMI MOTOYOSHI, TAKAO SUGIYAMA, SHIGENORI YAMAMOTO e MAKOTO SUEISHI. "Picropodophyllin and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells". Oncology Letters 8, n. 5 (27 agosto 2014): 2023–26. http://dx.doi.org/10.3892/ol.2014.2484.
OGIKU, T., S. YOSHIDA, T. KURODA, M. TAKAHASHI, H. OHMIZU e T. IWASAKI. "ChemInform Abstract: Syntheses of Aryltetralin Lignans: Concise Syntheses of (.+-.)- Isopodophyllotoxone, (.+-.)-Picropodophyllone and Related Compounds." ChemInform 24, n. 15 (20 agosto 2010): no. http://dx.doi.org/10.1002/chin.199315280.
Wong Te Fong, Anne-Christine, Thomas R. Eykyn, Harry G. Parkes, Aleksandra Bielen, Chris Jones, Ian R. Judson, John R. Griffiths, Martin O. Leach e Yuen-Li Chung. "Abstract B61: Picropodophyllin (PPP) increases glucose metabolism and lactate production in paediatric glioblastoma cells". Clinical Cancer Research 18, n. 10 Supplement (15 maggio 2012): B61. http://dx.doi.org/10.1158/1078-0432.mechres-b61.
Meresse, Philippe, Claude Monneret e Emmanuel Bertounesque. "Synthesis of podophyllotoxin analogues: δ-lactone-containing picropodophyllin, podophyllotoxin and 4′-demethyl-epipodophyllotoxin derivatives". Tetrahedron 60, n. 11 (marzo 2004): 2657–71. http://dx.doi.org/10.1016/j.tet.2004.01.017.
Lemaire, Miguel, Charlotte Fristedt, Prasoon Agarwal, Eline Menu, Els Van Valckenborgh, Elke De Bruyne, Anders Österborg et al. "The HDAC Inhibitor LBH589 Enhances the Antimyeloma Effects of the IGF-1RTK Inhibitor Picropodophyllin". Clinical Cancer Research 18, n. 8 (5 marzo 2012): 2230–39. http://dx.doi.org/10.1158/1078-0432.ccr-11-1764.
Zhang, Qi, Jing Pan, Ronald A. Lubet, Yian Wang e Ming You. "Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention". Molecular Carcinogenesis 54, S1 (27 agosto 2014): E129—E137. http://dx.doi.org/10.1002/mc.22206.
Bieghs, Liesbeth, Susanne Lub, Karel Fostier, Ken Maes, Els Van Valckenborgh, Eline Menu, Hans E. Johnsen et al. "The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic". Oncotarget 5, n. 22 (30 aprile 2014): 11193–208. http://dx.doi.org/10.18632/oncotarget.1933.
Dong, Lin, Meirong Du e Qianzhou Lv. "Picropodophyllin inhibits type I endometrial cancer cell proliferation via disruption of the PI3K/Akt pathway". Acta Biochimica et Biophysica Sinica 51, n. 7 (6 giugno 2019): 753–60. http://dx.doi.org/10.1093/abbs/gmz055.
Yoshida, Shin-ichi, Takeshi Yamanaka, Tutomu Miyake, Yasunori Moritani, Hiroshi Ohmizu e Tameo Iwasaki. "Asymmetric syntheses of lignans utilizing novel diastereoselective Michael addition of cyanohydrin: Syntheses of (+)-fargesin and (−)-picropodophyllone". Tetrahedron 53, n. 28 (luglio 1997): 9585–98. http://dx.doi.org/10.1016/s0040-4020(97)00643-1.
Yin, S., A. Girnita, T. Stromberg, Z. Khan, S. Andersson, H. Zheng, C. Ericsson et al. "Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma". Neuro-Oncology 12, n. 1 (20 ottobre 2009): 19–27. http://dx.doi.org/10.1093/neuonc/nop008.
YOSHIDA, S., T. YAMANAKA, T. MIYAKE, Y. MORITANI, H. OHMIZU e T. IWASAKI. "ChemInform Abstract: Asymmetric Syntheses of Lignans Utilizing Novel Diastereoselective Michael Addition of Cyanohydrin: Syntheses of (+)-Fargesin and (-)- Picropodophyllone." ChemInform 28, n. 50 (2 agosto 2010): no. http://dx.doi.org/10.1002/chin.199750276.
Waraky, Ahmed, Karen Akopyan, Vendela Parrow, Thomas Strömberg, Magnus Axelson, Lars Abrahmsén, Arne Lindqvist, Olle Larsson e Eiman Aleem. "Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism". Oncotarget 5, n. 18 (31 luglio 2014): 8379–92. http://dx.doi.org/10.18632/oncotarget.2292.
Economou, Mario A., Sandra Andersson, Diana Vasilcanu, Charlotta All-Ericsson, Eline Menu, Ada Girnita, Leonard Girnita, Magnus Axelson, Stefan Seregard e Olle Larsson. "Oral Picropodophyllin (PPP) Is Well Tolerated In Vivo and Inhibits IGF-1R Expression and Growth of Uveal Melanoma". Investigative Opthalmology & Visual Science 49, n. 6 (1 giugno 2008): 2337. http://dx.doi.org/10.1167/iovs.07-0819.
Economou, Mario A., Sandra Andersson, Diana Vasilcanu, Charlotta All-Ericsson, Eline Menu, Ada Girnita, Leonard Girnita, Magnus Axelson, Stefan Seregard e Olle Larsson. "Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma". Acta Ophthalmologica 86, esis4 (19 novembre 2008): 35–41. http://dx.doi.org/10.1111/j.1755-3768.2008.01184.x.
Jiang, Li-hua, Nian-yun Yang, Xiao-lin Yuan, Yi-jie Zou, Ze-qun Jiang, Feng-ming Zhao, Jian-ping Chen, Ming-yan Wang e Da-xiang Lu. "Microarray Analysis of mRNA and MicroRNA Expression Profile Reveals the Role ofβ-Sitosterol-D-glucoside in the Proliferation of Neural Stem Cell". Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/360302.
Conti, Laura, Gabriella Regis, Angela Longo, Paola Bernabei, Roberto Chiarle, Mirella Giovarelli e Francesco Novelli. "In the absence of IGF-1 signaling, IFN-γ suppresses human malignant T-cell growth". Blood 109, n. 6 (5 dicembre 2006): 2496–504. http://dx.doi.org/10.1182/blood-2006-07-034231.
Gong, Wan, Naidan Zhang, Gang Cheng, Quanlong Zhang, Yuqiong He, Yi Shen, Qi Zhang, Bo Zhu, Qiaoyan Zhang e Luping Qin. "Rehmannia glutinosa Libosch Extracts Prevent Bone Loss and Architectural Deterioration and Enhance Osteoblastic Bone Formation by Regulating the IGF-1/PI3K/mTOR Pathway in Streptozotocin-Induced Diabetic Rats". International Journal of Molecular Sciences 20, n. 16 (15 agosto 2019): 3964. http://dx.doi.org/10.3390/ijms20163964.
WU, YONG-TAO, BAO-JUN WANG, SHENG-WU MIAO e JIAN-JUN GAO. "Picropodophyllin inhibits the growth of Ewing's sarcoma cells through the insulin-like growth factor-1 receptor/Akt signaling pathway". Molecular Medicine Reports 12, n. 5 (28 agosto 2015): 7045–50. http://dx.doi.org/10.3892/mmr.2015.4266.
Liao, Fenfang, Yongheng Chen, Qingqing Wu, Jiaqi Wen, Xiangjie Chen, Weizhang Wang, Dan Xu e Manyu Liu. "Selective elimination of CML stem/progenitor cells by picropodophyllin in vitro and in vivo is associated with p53 activation". Biochemical and Biophysical Research Communications 579 (novembre 2021): 1–7. http://dx.doi.org/10.1016/j.bbrc.2021.09.029.
Vasilcanu, R., D. Vasilcanu, L. Rosengren, N. Natalishvili, B. Sehat, S. Yin, A. Girnita, M. Axelson, L. Girnita e O. Larsson. "Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1". Oncogene 27, n. 11 (10 settembre 2007): 1629–38. http://dx.doi.org/10.1038/sj.onc.1210797.
Mo, Hai-Ying, Qi-Yao Wei, Qiu-Hua Zhong, Xiao-Yun Zhao, Dan Guo, Jin Han, Wachiraporn Noracharttiyapot et al. "Cytochrome P450 27C1 Level Dictates Lung Cancer Tumorigenicity and Sensitivity towards Multiple Anticancer Agents and Its Potential Interplay with the IGF-1R/Akt/p53 Signaling Pathway". International Journal of Molecular Sciences 23, n. 14 (16 luglio 2022): 7853. http://dx.doi.org/10.3390/ijms23147853.
Menu, Eline, Helena Jernberg-Wiklund, Thomas Stromberg, Hendrik De Raeve, Leonard Girnita, Olle Larsson, Magnus Axelson et al. "Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model". Blood 107, n. 2 (15 gennaio 2006): 655–60. http://dx.doi.org/10.1182/blood-2005-01-0293.
Takata, Sho, Hiromi Sakata-Haga, Hiroki Shimada, Tsuyoshi Tsukada, Daisuke Sakai, Hiroki Shoji, Mitsuhiro Tomosugi et al. "LIF–IGF Axis Contributes to the Proliferation of Neural Progenitor Cells in Developing Rat Cerebrum". International Journal of Molecular Sciences 23, n. 21 (30 ottobre 2022): 13199. http://dx.doi.org/10.3390/ijms232113199.
Razuvaev, Anton, Bimma Henderson, Leonard Girnita, Olle Larsson, Magnus Axelson, Ulf Hedin e Joy Roy. "The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling". Journal of Vascular Surgery 46, n. 1 (luglio 2007): 108–15. http://dx.doi.org/10.1016/j.jvs.2007.02.066.
Wu, Qi, Ai-Ling Tian, Bei Li, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren Galloway et al. "IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms−". Journal for ImmunoTherapy of Cancer 9, n. 6 (giugno 2021): e002722. http://dx.doi.org/10.1136/jitc-2021-002722.
Economou, Mario A., Jiangmei Wu, Daiana Vasilcanu, Linda Rosengren, Charlotta All-Ericsson, Ingeborg van der Ploeg, Eline Menu et al. "Inhibition of VEGF Secretion and Experimental Choroidal Neovascularization by Picropodophyllin (PPP), an Inhibitor of the Insulin-like Growth Factor-1 Receptor". Investigative Opthalmology & Visual Science 49, n. 6 (1 giugno 2008): 2620. http://dx.doi.org/10.1167/iovs.07-0742.
Economou, Mario A., Jiangmei Wu, Daiana Vasilcanu, Linda Rosengren, Charlotta All-Ericsson, Ingeborg Van Der Ploeg, Eline Menu et al. "Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor". Acta Ophthalmologica 86, esis4 (19 novembre 2008): 42–49. http://dx.doi.org/10.1111/j.1755-3768.2008.01185.x.
E, Changyong, Jing Li, Dan Shao, Dan Zhang, Yue Pan, Li Chen e Xuewen Zhang. "The Insulin-Like Growth Factor-I Receptor Inhibitor Picropodophyllin-Induced Selective Apoptosis of Hepatocellular Carcinoma Cell Through a Caspase-Dependent Mitochondrial Pathway". Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 21, n. 2 (10 gennaio 2014): 103–10. http://dx.doi.org/10.3727/096504013x13808175127324.
Girnita, Ada, Charlotta All-Ericsson, Mario A. Economou, Kristina Astr√∂m, Magnus Axelson, Stefan Seregard, Olle Larsson e Leonard Girnita. "The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells." Clinical Cancer Research 12, n. 4 (15 febbraio 2006): 1383–91. http://dx.doi.org/10.1158/1078-0432.ccr-05-1106.
Duan, Zhenfeng, Edwin Choy, David Harmon, Cao Yang, Keinosuke Ryu, Joseph Schwab, Henry Mankin e Francis J. Hornicek. "Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines". Molecular Cancer Therapeutics 8, n. 8 (28 luglio 2009): 2122–30. http://dx.doi.org/10.1158/1535-7163.mct-09-0115.
Gullbo, Joachim, Michael Bergqvist, Malin Wickström, Peter Ericsson, Linda Sooman, Daniel Brattström, Stefan Bergström e Simon Ekman. "P3-016: In vitro activity of picropodophyllin in lung cancer cell lines and association to the insulin-like Growth Factor-1 receptor". Journal of Thoracic Oncology 2, n. 8 (agosto 2007): S613—S614. http://dx.doi.org/10.1097/01.jto.0000283773.72586.f8.