Tesi sul tema "Paediatrics"
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Sylvester, Dianne. "Genes underpinning predisposition to childhood cancer". Thesis, The University of Sydney, 2020. https://hdl.handle.net/2123/22458.
Testo completoStar, Kristina. "Safety of Medication in Paediatrics". Doctoral thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197323.
Testo completoBoss, Patricia M., e res cand@acu edu au. "Indicators of Satisfaction & Success For a Paediatric Outreach Nursing Service in Metropolitan Sydney, NSW". Australian Catholic University. School of Nursing, 2005. http://dlibrary.acu.edu.au/digitaltheses/public/adt-acuvp118.25102006.
Testo completoMoore, Ryan. "International Normalised Ratio Monitoring in Children: Comparing the accuracy of portable point-of-care monitors to standard of care laboratory monitoring at Red Cross War Memorial Children's Hospital". Master's thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/32880.
Testo completoNaidoo, Nayestha. "Neonatal Sepsis And Antibiotic Sensitivity Patterns At A South African Tertiary Nursery – Evolution Over A 15 Year Period". Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31063.
Testo completoLupton-Smith, Alison Rosalie. "An investigation into regional ventilation in infants and children; its distribution and determinants". Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24911.
Testo completoGithinji, Leah Nyawira. "Lung function in perinatally HIV-infected adolescents on antiretroviral therapy in Cape Town, South Africa". Doctoral thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31387.
Testo completoHorn, Alan Richard. "Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting". Doctoral thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/11188.
Testo completoHypoxic ischaemic encephalopathy (HIE) after birth is an important cause of neonatal morbidity and mortality, particularly in resource-limited regions. Therapeutic hypothermia initiated within the first 6 hours of life, in settings that can offer neonatal intensive care, is a therapy that can reduce death or severe disability in newborn infants with moderate or severe HIE. Therapeutic hypothermia has not been shown to be safe or effective in low-resource settings where neonatal intensive care is not available; however, there are situations such as in some centres in South Africa, where limited neonatal intensive care (NICU) is available against a background of moderate neonatal mortality rates, relatively low socio-economic conditions and limited capacity for long-term follow-up. In such settings, accurate case definition and early prediction of HIE and outcome may assist with the appropriate allocation of resources. The amplitude-integrated electro-encephalogram (aEEG) is an ideal tool to use for prediction of outcome and the need for cooling, but it’s availability is limited, particularly at primary and secondary hospitals.
Thompson, Mary Clare. "Neurodevelopmental outcome of the high risk infant in Cape Town". Doctoral thesis, University of Cape Town, 2000. http://hdl.handle.net/11427/25807.
Testo completoGray, Claudia Liesel. "The prevalence and patterns of IgE-mediated food allergy and sensitisation in South African children with atopic dermatitis". Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/12874.
Testo completoBackground: The prevalence of food allergy in South Africa is unknown, but previously thought to be low, particularly in black South Africans. We hypothesised that food allergies would be low in Xhosa patients, even those at increased risk of food allergy such as children with atopic dermatitis (AD). This study aimed to determine the prevalence of, patterns and risk factors for, IgE-mediated food allergy in South African children with moderate to severe AD. It is the first food allergy prevalence study in South Africa to utilise controlled food challenges and component analysis, and is unique for its comparison of food allergy patterns between ethnic groups in the same geographical area. Methodology: This was a prospective, observational study in a paediatric university hospital in Cape Town. Children with moderate to severe AD, aged 6 months to 10 years, were randomly recruited from the dermatology clinic. They were assessed for sensitisation and allergy by questionnaire, skin prick tests (SPT), Immuno Solid Phase Allergen Chip (ISAC) test and incremental food challenges. Sensitised patients were also tested for specific IgE by ImmunoCAP test. Results: One hundred participants (59 black Africans and 41 of mixed race) were enrolled, median age 42 months. There were high overall rates of food sensitisation (66%) and food allergy (40%). Egg (25%) and peanut (24%) were the most common allergies. Black participants had comparable sensitisation (69% vs 61%) but lower allergy rates (34% vs 46%) than mixed race participants. This was especially evident for peanut allergy (15% vs 37%, p=0.01). Early onset AD (< 6 months), severe eczema, and young age < 2 years were significant risk factors for food allergy. The ISAC test was less sensitive than SPT and ImmunoCAP tests. Only 42% of cases of perceived food allergy were confirmed as true food allergy.
Botes, Alida Maria. "A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22985.
Testo completoLaurence, Craig. "Correlation between pro-inflammatory alleles and clinical and laboratory markers of allergy in Xhosa South Africans". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22821.
Testo completoWeakley, Kate. "Juvenile idiopathic arthritis in two tertiary centres in the Western Cape, South Africa". Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/10744.
Testo completoNuttall, James Jolyon Care. "The performance of HIV rapid antibody detection assays in children". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20296.
Testo completoOmarjee, Zakiyya. "An audit of endocrine dysfunction in children with craniopharyngiomas at Red Cross Children's Hospital and Groote Schuur Hospital from 1976 to 2004". Master's thesis, University of Cape Town, 2006. http://hdl.handle.net/11427/26765.
Testo completoSpittal, Graeme William. "Characteristics of childhood-onset Systemic Lupus Erythematosus in Cape Town, South Africa". Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/6016.
Testo completoWiles, Jodi Isaacs. "Descriptive study evaluating the use of the Road to Health card by doctors in a tertiary paediatric hospital setting". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20295.
Testo completoProcter, Claire. "Lumbar punctures in the paediatric emergency medicine department at Red Cross War Memorial Children's Hospital: An evaluation". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20854.
Testo completoNorth, Natasha. "What is the capacity of the children's nursing workforce in seven selected Sub-Saharan African countries? Gathering insights from Botswana, Kenya, Namibia, Malawi, South Africa, Uganda and Zambia". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29838.
Testo completoSwitala, Juli. "Evaluation of children with haemophagocytic lymphohistiocytosis (HLH) at Red Cross War Memorial Children's Hospital 1991-2010". Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/11104.
Testo completoHaemophagocytic Lymphohistiocytosis (HLH) is a rare haematological disorder in children. However, this is probably an underestimation due to the difficulty in diagnosing the disease. HLH is characterized clinically by persistent fevers, organomegaly, cytopaenias and typical biochemical derangements viz. hypertriglyceridaemia, hyperferritinaemia and hypofibrinogenaemia. Other associated findings include decreased natural killer cell (NKC) function and raised soluble CD 25. The exact pathophysiology of HLH is not completely understood but involves a trigger (often an infection) which sets off an uncontrolled inflammatory cascade, characterized by an increase in hyperactivated macrophages and T lymphocytes which leads to increased production of cytokines, alongside reduced cellular cytotoxicity as a result of reduced or absent NKC function.
Browde, Kate. "Indication for and outcomes of continuous Positive Airways Pressure (CPAP) and High Flow Nasal Cannula oxygen therapy (HFNC) in children admitted to Red Cross War Memorial's Hospital (RCWMCH) excluding those with primary respiratory aetiologies". Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/25195.
Testo completoWicht, Carl Bryce. "Development and validation of a questionaire as a screening tool for developmental disability in 9 month old infants : September 1996 - January 1997". Master's thesis, University of Cape Town, 1999. http://hdl.handle.net/11427/26767.
Testo completoWebb, Nicholas Guy. "Assessment of the efficacy and efficiency of rapid rehydration in children with dehydration due to gastroenteritis in the rehydration unit of Red Cross War Memorial Children's Hospital". Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/27083.
Testo completoHendricks, Lesley Jill. "An analysis of the phenotypic features of chromosomes 22q11.1 deletion syndrome at Red Cross War Memorial Children's Hospital". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29805.
Testo completoDaniels, Adriaan. "Examining the reliability of discharge ICD coding in the Red Cross War Memorial Children's Hospital administrative database". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29811.
Testo completoSher, Rebecca Yael Nthabiseng. "Patterns of Detectable Viral Load in a cohort of HIV-infected adolescents on antiretroviral therapy". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29716.
Testo completoLe, Roux David Martin. "Incidence of bacteraemia in HIV-infected children in Africa, and the impact of highly active antiretroviral therapy". Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/11483.
Testo completoIncludes bibliographical references.
From November 2002 to December 2006, a placebo-controlled, randomized trial investigated the incidence of tuberculosis and the overall mortality in a cohort of HIV-infected children in Cape Town, South Africa. They were randomized to receive either Isoniazid Preventive Therapy (IPT) or placebo. In addition, they were randomized to receive trimethoprim/sulfamethoxaxole prophylaxis on either a daily or a three-times-per-week schedule. The aim: To describe the incidence of bacteraemia, and the spectrum of organisms cultured. To determine if there was a difference in the incidence of bacteraemia between children using Isoniazid Preventive Therapy (IPT) versus placebo; and to determine if there was a difference in the incidence of bacteraemias between the groups using daily versus thrice-weekly trimethoprim/sulphamethoxazole prophylaxis.
Machingaidze, Pamela Rudo. "The clinical use and indications for head computed tomography scans in paediatric ambulatory care (short stay ward and medical emergencies) at a children’s hospital over a one-year period, 1st January-31st December 2013". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29345.
Testo completoWestwood, Anthony Thomas Read. "Cystic fibrosis in children and adolescents in the Western Cape : epidemiological and clinical aspects". Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/10745.
Testo completoCystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations on chromosome 7 in the gene for the CFTR protein. This gene encodes for a chloride channel on the apical surface of certain epithelial cells. The clinical manifestations of CF largely arise out of the resultant defect in water and electrolyte secretions in exocrine glands and epithelia such as are found in the pancreas, respiratory, gastrointestinal and genital tracts and sweat glands. First delineated as a clinical entity in the mid-20th century, CF was shown to be identifiable through the demonstration of elevated electrolyte levels in sweat - the sweat test. After many false starts, the underlying genetic defect was identified in the 1980s, culminating in the identification of the defective gene in 1989. This opened up possibilities of more accurate diagnosis and targeted treatments. Treatment of CF with pancreatic enzyme replacement therapy and antibiotics in the 1950s proved successful in controlling some of the severe and often fatal aspects of the disease. Further refinements to nutritional and antimicrobial therapies in the 1970s and 1980s produced rapid increases in longevity in many patients with CF. In SA, CF' has been identified since the 1950s. Clinical and research activities developed in the 1980s, mainly focused on the epidemiological and genetic aspects. Two clinical studies described features in children in Cape Town and adults in Johannesburg. My own clinical involvement in the RCCH's CF Service in Cape Town since 1992 led to the research activities that make up the bulk of this thesis. The thesis describes a number of aspects of CF as it affects patients in SA. The study population (described in Chapter 2) for most of the projects consists of 181 CF patients born between October 1974 and September 2003 who were identified by a combination of clinical features, positive sweat or genetic tests and/or post-mortem findings. All were resident in the Western Cape Province and received at least part of their health care at the RCCH. One hundred and sixty (88%) were born in the province and 21 settled in the province from elsewhere. Cape Town is unique in SA for its population demographics and the CF patients reflect this. CF has mainly been identified in coloured and white patients. Four black cases have been diagnosed. Compared with the CF population as described in the early 1980s, the CF population in the 21st century is larger (100 versus 64), older and there is a greater proportion of coloured patients. Nearly 3 in every 4 patients live in Cape Town.
Wege, Martha Helena. "A retrospective review of the prevalence and management of anaemia in children in at Red Cross War Memorial Children's Hospital". Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/19898.
Testo completoIntroduction Childhood anaemia is a major public health problem, iron deficiency being most common. WHO estimates anaemia to occur in 24.1% of pre-school South African children. Our study describes prevalence and management of anaemia in children aged 6 - 36 months presenting to a children's hospital. Methods In a retrospective cross-sectional study, laboratory data were used to estimate prevalence of anaemia in children aged 6 - 36 month presenting to medical emergency or ambulatory services of Red Cross Children's Hospital in 2012. A random sample of 50% of anaemic children was sampled for detailed review. Results 2661 subjects were included. Anaemia (H b < 10.5) was found in 40.8 % (1088/2661. Children presenting to medical emergency had a higher prevalence of anaemia compared to those presenting to ambulatory services ( 42.7% vs. 34.9 % ; p=0.001 ). Anaemia prevalence increased with decreasing age with RR 1.25 (95% CI 1.10 - 1.43) and RR 1.15 (95% CI 1.02 - 1.31) in children aged 6 - 11 months and 12 - 23 months respectively compared to children aged 24 - 36 months. Microcytosis was found in 51.3% (558/1088) of anaemic children and in 19.3% (n=303/1573) of children without anaemia ; p<0.001 Folders were reviewed i n 502 children with anaemia , 36.1% had mild anaemia (Hb 10 - 10.5g/dl), while moderate ( Hb 8 - 10 g/dl ) and severe ( Hb < 8 g/dl ) anaemia was found in 52.5% and 11.4% respectively. Breastfeeding for longer than six months was associated with higher risk of microcytic anaemia [RR 1.26 (95%CI 1.08 - 1.47)]. Only 12.2 % (31 /254) of children with microcytic anaemia received adequate iron therapy, 50.0 % (127/254) received no iron therapy. Conclusions Prevalence of anaemia in children presenting to hospital is higher than predicted for well children in South Africa. The risk is higher in younger and acutely sick children. Prolonged breasting is associated with increased risk of microcytosis. Most children with suspected iron deficiency anaemia did not receive appropriate treatment.
Reddy, Deveshnee. "Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa". Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/13974.
Testo completoLampel, Netanya. "Screening of the human tumor necrosis factor (TNF) gene and its receptor 1 (TNFR1) gene for DNA alterations and the subsequent investigation of these and an IL12p40 polymorphism for an association with paediatric tuberculosis". Master's thesis, University of Cape Town, 2004. http://hdl.handle.net/11427/8628.
Testo completoInfection with Mycobacterium tuberculosis is characterised by diverse outcomes; the majority of infected individuals remain well and yet others develop disease ranging from limited pulmonary tuberculosis to severe disseminated disease. The reasons for this diverse outcome are poorly understood, but host factors are thought to play an important role. In particular, a genetic component to susceptibility to tuberculosis has been proposed. An important clue was the description of a group of Maltese children with an unusual susceptibility to progressive non-tuberculous mycobacterial infections. These patients showed defective tumor necrosis factor (TNF) production in response to endotoxin and a failure to upregulate TNF production in response to interferon gamma as well as diminished interferon gamma production during T-cell proliferation. They were found to lack expression of the interferon gamma receptor ligand-binding chain (IFN-yR1) on their cell surfaces due to a single point substitution resulting in a truncated protein. Since then other defects in the type 1 cytokine pathway leading to susceptibility to non-tuberculous mycobacteria, as well as to tuberculosis, have been described in rare isolated cases. From these findings, the hypothesis arose that less severe mutations in such pathways might individually, or in combination, lead to increased susceptibility to tuberculosis in the general population. The following study forms part of a larger multi-centre collaboration, which aims to better understand the genetic basis of susceptibility to mycobacterial infection by addressing this hypothesis. The approach taken has been the recruitment and immuno-phenotyping of a large group of children with tuberculosis as well as control subjects. Candidate genes, of the type 1 cytokine pathways being investigated, include interferon gamma, interleukin12 and their receptors and TNF. The focus of the study described in this thesis has been the screening of a sub-cohort of patients and control subjects for DNA sequence alterations in the TNF and TNFR1 genes. The individuals in this cohort were selected on the basis of their whole blood stimulation assays, where either high or low levels of TNF in response to non-specific stimulatory factors, were the determining criteria. It was assumed that these two phenotypic groupings would be enriched for gene variants contributing to the TNF responses recorded in the stimulation assays. Once identified, these polymorphisms would be screened for frequencies in the broader patient and control groupings and assessed for any association with susceptibility to tuberculosis. This study was considered important in attempting to explain which genes and their polymorphisms are involved in determining the high prevalence of tuberculosis in African populations.
Robertson, Gillian. "Hypernatraemic gastroenteritis in critically ill children". Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/9261.
Testo completoLevin, Lindsey Nicola. "Biliary atresia at Red Cross War Memorial Children's Hospital: A retrospective descriptive study reviewing the age of presentation, clinical course and outcome of infants presenting to RCWMCH with biliary atresia". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22822.
Testo completoHutton, Hayley. "Clinical features and outcome of patients with severe lower respiratory tract infection admitted to a Paediatric Intensive Care Unit in the Western Cape, South Africa". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/24501.
Testo completoThomas, Karla Mari. "Bacterial meningitis in neonates and children South Africa". Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/10743.
Testo completoAcute bacterial meningitis is defined as the inflammation of the meninges. It is caused by various bacteria and the specific aetiology is age dependant. In the neonatal period the causative organisms are: Group B streptococci, Gram - negative bacilli (e.g.: E. coli, Klebsiella spp, Enterobacter spp, Salmonella spp) and Listeria monocytogenes. In infants and children up to the age of 5 the most common causative organisms include: Streptococcus pneumoniae, Haemophilus influenzae type B (Hib)and Neiseria meningitidis. The two chief causes of bacterial meningitis in children older than 5 are S. pneumoniae and N. meningitidis. Various studies have been performed to look at the profile of meningitis among the paediatric population. Objective: To investigate the aetiology of acute bacterial meningitis in South African newborns and children from 2005 - 2010.
Chippendale, Sa-Eeda. "Severe allergic reactions at a tertiary paediatric service 2014 - 2016". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29566.
Testo completoVandenbroucke, Natalie Joëlle. "Lung function determinants and mortality of children and adolescents with cystic fibrosis in South Africa 2007-2016". Master's thesis, Faculty of Health Sciences, 2019. https://hdl.handle.net/11427/31782.
Testo completoHatherill, Mark. "Transport of critically ill children in a resource-limited setting". Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/10987.
Testo completoTransportation of critically ill children by inexperienced personnel may be associated with increased risk of transfer-related adverse events and mortality. To audit paediatric intensive care unit (PICU) transfer activity and transfer-related adverse events in a resource-limited setting. Twenty-two bed regional PICU of a university children's hospital in Cape Town, South Africa. Prospective one-year audit of all children transferred directly to PICU from other hospitals. Data were collected for patient demographics and diagnostic category, referring hospital, transferring personnel, mode of transport, and the incidence of technical, clinical, and critical adverse events. Data are median (interquartile range, IQR). The transfers of 202 children, median age 2.8 months (1.1-14), median weight 3.5 kg (2.5-8.1) were analysed.
Copelyn, Julie. "Short-term outcomes of downreferral in provision of paediatric antiretroviral therapy at Red Cross War Memorial Childrens Hospital, Cape Town". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22761.
Testo completoMukuddem-Sablay, Zakira. "Adenovirus-associated pneumonia in South African children : presentation, clinical course and outcome". Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16697.
Testo completoBackground: Pneumonia is an important cause of morbidity and mortality in children. Viruses have emerged as important aetiological agents in childhood pneumonia. The aim of this study was to document the clinical presentation, severity and outcome of adenoviral-associated pneumonia (AVP) in children and identify risk factors associated with poor outcome. Methods: A retrospective study of laboratory-confirmed AVP cases was conducted between 1 January and 31 December 2011. The medical records of adenovirus PCR positive respiratory tract samples identified through the National Health Laboratory Service (NHLS) database were retrieved. Demographic, clinical and outcomes data of children with AVP were extracted and analysed. Outcome measures were death and development of chronic lung disease (CLD). Results: 1910 respiratory samples were submitted to the NHLS from which 206/1910 (11%) AVP cases were identified. The median age was 12 months (IQR 6-24), 70 (34%) children were malnourished and 14 (7%) HIV-infected. Fever was the commonest presenting symptom occurring in 159 (77%) of cases. Seventy six (37%) required intensive care unit (ICU) admission. There was a high prevalence of co-morbid conditions with 98 (47%) having at least one; cardiac disease was the most common (48 (23%). Twenty nine (14%) developed CLD which was associated with hypoxia at presentation (26/29, 90%, p = 0.01) and admission to ICU (18/29, 62%, p < 0.01). Eighteen (9%) children died. Admission to ICU (OR 8.3, 95% CI 2.3-29.0) and blood stream infection (OR 11.2; 95% CI 2.3-54.1) were independent risk factors for mortality. Conclusion: Adenoviral-associated pneumonia is an important cause of pneumonia and CLD in young children in South Africa. Admission to ICU and blood stream infection were associated with poor outcome
Frigati, Lisa Jane. "The impact of isoniazid preventative therapy and antiretroviral therapy on tuberculosis (TB) in HIV-infected children in a high TB incidence setting". Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/10467.
Testo completoMoore, David Paul. "Aspect of tuberculosis case management at Red Cross Children's Hospital". Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/10863.
Testo completoIncludes bibliographical references (leaves 151-165).
Aim: To describe the spectrum of tuberculosis in children <15 years of age attending Red Cross War Memorial Children's Hospital between January 2006 and December 2008. Methods: A retrospective review of a paper-based Notifications Register and a database of culture-confirmed tuberculosis were undertaken. Laboratory and clinical data were analysed. Results: 1,314 episodes of tuberculosis were identified amongst 1,300 children. 433 (33%) of all cases were culture-confirmed; however, 120 (27.7%) of all culture-confirmed cases were not recorded in the paper-based Notifications Register. Conclusions: To improve the clinical service, detection of HIV co-infection in children undergoing evaluation for tuberculosis should be enhanced and strategies adopted to ensure that all children with culture- confirmed disease are notified and access antituberculosis therapy.
Argent, Andrew Charles. "The mechanics of breathing in acute severe croup". Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/10054.
Testo completoIncludes bibliographical references.
Croup is a common respiratory illness that has been recognized for many years. Despite recent advances in the utilization of steroids to treat the condition, it remains a significant cause of morbidity in children. In the developing world it may also remain a significant cause of mortality. Despite comprehensive descriptions of the disease process, its aetiological agents and clinical course, there are very few descriptions of the mechanics of breathing in croup. In addition there are very few methods described of measuring the severity of airway obstruction in patients with croup.
Van, Dyk Jessi Grace. "Maternal methamphetamine use during pregnancy and subsequent neurodevelopmental and psychological sequelae in the child - a Cape Town experience". Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/14814.
Testo completoMethamphetamine, part of the amphetamine group of drugs, was first discovered in Japan in 1919. It has been clandestinely manufactured in the United States since the 1960s, and is still legally produced there as a nasal inhalant, as treatment for Attention Deficit Disorder and exogenous obesity, as well as off-label treatment for narcolepsy. (1) It is a cheap (about R15- 30 per 'straw'), easily obtainable, odourless, white powder, which has a bitter, taste, but dissolves easily in water or alcohol. Known as, amongst others, ' speed', 'ice', 'crystal', 'chalk', 'glass', 'crank', and locally, 'tik', it can be smoked, snorted, orally ingested, injected intravenously or even administered anally. In South Africa the preferred method consists of placing the powder or crystal in a light bulb (from which the metal threading has been removed) and inhaling the fumes produced while heating the bulb from below with a lighter.(2). The use of methamphetamine has risen sharply globally over the last decade, used by 26 million people worldwide by 2007, more than heroin and cocaine combined, according to the United Nations Office on Drugs and Crime. This has been ascribed to many interlocking reasons: it is cheap, easily obtainable, easy to use without the need for needles or other special 'equipment', and it produces in the user a characteristic 'rush'. This feeling of confidence, power and heightened sexual levels, of feeling 'on top of the world' has made it especially popular amongst teenagers and young adults. (3)
Meyer, Mandy-Lyn. "A review of children admitted to a regional hospital in Cape Town with community acquired pneumonia". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20297.
Testo completoMvalo, Tisungane Knox Titus. "Blood stream infections in oncology patients at Red Cross War Memorial Children's Hospital, Cape Town". Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/27377.
Testo completoAyuk, Adaeze Chikaodinaka. "Environmental risk factors for asthma in 13-14 year old African children". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29369.
Testo completoNupen, Tracey Lee. "Characteristics and outcome of long-stay patients in a paediatric intensive care unit in Cape Town, South Africa". Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/19902.
Testo completoAkhalwaya, Shehnaaz. "Management of paediatric immune thrombocytopaenia in a South African centre from 1991-2011". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22793.
Testo completo