Letteratura scientifica selezionata sul tema "Ophiorrhine A"

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Articoli di riviste sul tema "Ophiorrhine A"

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Shi, Bao-bao, Hong-Lian Ai, Kai-Ting Duan, Tao Feng e Ji-Kai Liu. "Ophiorrhines F and G, Key Biogenetic Intermediates of Ophiorrhine Alkaloids from Ophiorrhiza japonica and Their Immunosuppressant Activities". Journal of Natural Products 85, n. 2 (1 febbraio 2022): 453–57. http://dx.doi.org/10.1021/acs.jnatprod.1c01085.

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Arbain, Dayar, Lindsay T. Byrne,, Dachriyanus, Noversa Evrayoza e Melvyn V. Sargent. "Bracteatine, a Quaternary Glucoalkaloid from Ophiorrhiza bracteata". Australian Journal of Chemistry 50, n. 11 (1997): 1111. http://dx.doi.org/10.1071/c97055.

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Abstract (sommario):
Extraction of the aerial parts of Ophiorrhiza bracteata Bl. (Rubiaceae) has yielded the known quaternary indole alkaloid ophiorrhizine (1) and the new glucoindole alkaloid bracteatine (2), the structure of which followed from its spectroscopic properties.
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Feng, Tao, Kai-Ting Duan, Shi-Jun He, Bin Wu, Yong-Sheng Zheng, Hong-Lian Ai, Zheng-Hui Li, Juan He, Jian-Ping Zuo e Ji-Kai Liu. "Ophiorrhines A and B, Two Immunosuppressive Monoterpenoid Indole Alkaloids from Ophiorrhiza japonica". Organic Letters 20, n. 24 (10 dicembre 2018): 7926–28. http://dx.doi.org/10.1021/acs.orglett.8b03489.

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Arbain, Dayar, Lindsay T. Byrne, Deddi Prima Putra, Melvyn V. Sargent, Brian W. Skelton e Allan H. White. "Ophiorrhizine, a new quaternary indole alkaloid related to cinchonamine, from Ophiorrhiza major Ridl." Journal of the Chemical Society, Perkin Transactions 1, n. 6 (1992): 663. http://dx.doi.org/10.1039/p19920000663.

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ARBAIN, D., L. T. BYRNE, D. P. PUTRA, M. V. SARGENT, B. W. SKELTON e A. H. WHITE. "ChemInform Abstract: Ophiorrhizine, a New Quaternary Indole Alkaloid Related to Cinchonamine, from Ophiorrhiza major Ridl." ChemInform 23, n. 29 (21 agosto 2010): no. http://dx.doi.org/10.1002/chin.199229268.

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FUJII, Tozo, Masashi OHBA e Shigeki SETO. "Quinolizidines. XXXIII. A Chiral Synthesis of (-)-Ophiorrhizine, a Pentacyclic Quaternary Indole Alkaloid from Ophiorrhiza major RIDL." CHEMICAL & PHARMACEUTICAL BULLETIN 43, n. 1 (1995): 49–52. http://dx.doi.org/10.1248/cpb.43.49.

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Birina, Bhuyan, e Baruah Sanjib. "On the extended distribution of two species of Ophiorrhiza L. (Rubiaceae) from the States of India". Plant Science Today 9, n. 4 (19 ottobre 2022): 1085–89. http://dx.doi.org/10.14719/pst.1769.

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Abstract (sommario):
Ophiorrhiza L. (1753: 150) is a pantropical, herbaceous genus distributed with high diversity in South East Asia. Here, 2 members of genus Ophiorrhiza, Ophiorrhiza brunonis var. johnsonii Hook. f. reported as a new record for North East India and Ophiorrhiza fasciculata D. Don for the flora of Assam. Detailed taxonomic descriptions, coloured photographs are provided here for the easy identification of the taxa. Distribution map of the species is also provided.
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Sankaran, HAREESH Vadakkoot, Sreekumar Vadakkethil Balakrishnan, PRABHU KUMAR Konikkal Mambetta, NIRMESH Thankappan Kureekadu e Sreejith Kalpuzha Ashtamoorthy. "Ophiorrhiza sahyadriensis (Rubiaceae), a new species from southern Western Ghats, Kerala, India". Phytotaxa 202, n. 3 (13 marzo 2015): 219. http://dx.doi.org/10.11646/phytotaxa.202.3.6.

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Abstract (sommario):
A new species of Ophiorrhiza (Rubiaceae) is described from southern Western Ghats, Kerala, India. The new species, Ophiorrhiza sahyadriensis, is similar to Ophiorrhiza brunonis, an endangered species endemic to Western Ghats, to which is compared. Detailed description, distribution, ecology, phenology and relevant taxonomic notes are provided along with colour photographs and illustrations.
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FUJII, T., M. OHBA e S. SETO. "ChemInform Abstract: Quinolizidines. Part 33. A Chiral Synthesis of (-)-Ophiorrhizine (VII), a Pentacyclic Quaternary Indole Alkaloid from Ophiorrhiza major RIDL." ChemInform 26, n. 31 (17 agosto 2010): no. http://dx.doi.org/10.1002/chin.199531221.

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Pham, Mai Huong, Thu Hoai Tran, Thi Dung Le, Tung Lam Le, Ha Hoang e Hoang Ha Chu. "The Complete Chloroplast Genome of An Ophiorrhiza baviensis Drake Species Reveals Its Molecular Structure, Comparative, and Phylogenetic Relationships". Genes 14, n. 1 (15 gennaio 2023): 227. http://dx.doi.org/10.3390/genes14010227.

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Abstract (sommario):
Ophiorrhiza baviensis Drake, a flowering medical plant in the Rubiaceae, exists uncertainly within the Ophiorrhiza genus’ evolutionary relationships. For the first time, the whole chloroplast (cp) genome of an O. baviensis Drake species was sequenced and annotated. Our findings demonstrate that the complete cp genome of O. baviensis is 154,770 bp in size, encoding a total of 128 genes, including 87 protein-coding genes, 8 rRNAs, and 33 tRNAs. A total of 59 SSRs were screened in the studied cp genome, along with six highly variable loci, which can be applied to generate significant molecular markers for the Ophiorrhiza genus. The comparative analysis of the O. baviensis cp genome with two published others of the Ophiorrhiza genus revealed a high similarity; however, there were some notable gene rearrangements in the O. densa plastome. The maximum likelihood phylogenetic trees were constructed based on the concatenation of the rps16 gene and the trnL-trnF intergenic spacer sequence, indicating a close relationship between the studied O. baviensis and other Ophiorrhiza. This study will provide a theoretical molecular basis for identifying O. baviensis Drake, as well as species of the Ophiorrhiza genus, and contribute to shedding light on the chloroplast genome evolution of Rubiaceae.
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Tesi sul tema "Ophiorrhine A"

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Cao, Wei. "Total synthesis of ophiorrhine A, G and ophiorrhiside E and synthetic studies towards the total synthesis of pestalustaine A". Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF077.

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Abstract (sommario):
L'ophiorrhine A, G et l'ophiorrhiside E sont des alcaloïdes indolomonoterpéniques isolés des plantes Ophiorrhiza japonica et Trichocarpon. Nous avons réalisé la première synthèse totale de l'ophiorrhine A, G et de l'ophiorrhiside E. Plusieurs stratégies ont été explorées pour construire la partie indolopyridone de l'ophiorrhiside E, le précurseur biosynthétique supposé de l'ophiorrhine A. Finalement, le couplage de type Friedel-Crafts de l'indolyl-acétamide avec le chlorure d'acide dérivé de la sécologanine a conduit à l'ophiorrhine G. La cyclodéshydratation d'une forme protégée de ce dernier a été suivie par la cycloaddition de Diels-Alder intramoléculaire spontanée de l'ophiorrhiside E protégée, menant à l'ophiorrhine A, qui peut se transformer en un produit non naturel avec un squelette de carbazole. La pestalustaïne A est un sesquiterpénoïde isolé du champignon endophyte pestalotiopsis adusta dont nous avons investigué la synthèse totale. Nous avons réalisé une expansion de cycle à partir d'un intermédiaire à 6 chaînons pour former un noyau à 7 chaînons, suivie par une fermeture de cycle par métathèse d'un diène pour construire un squelette ponté 7/7, et une addition 1,4 intramoléculaire pour obtenir le tricycle 7/5/6. L'analyse des résultats de diffraction des rayons X pour un intermédiaire contenant le noyau 7/5/6 a révélé des écarts entre notre structure et celle proposée précédemment. L'analyse des spectres du produit naturel isolé a suggéré que la structure avait peut-être été mal attribuée
Ophiorrhine A, G and ophiorrhiside E are monoterpene indole alkaloids which were isolated from the plant Ophiorrhiza japonica and trichocarpon. We achieved the first total synthesis of ophiorrhine A, G and ophiorrhiside E. Several strategies were investigated to construct the indolopyridone moiety of ophiorrhiside E, the postulated biosynthetic precursor of ophiorrhine A. Eventually, the Friedel-Crafts-type coupling of indolyl-acetamide with secologanin-derived acid chloride delivered ophiorrhine G. Cyclodehydratation of a protected form of the latter was followed by the desired spontaneous intramolecular Diels-Alder cycloaddition of protected ophiorrhiside E leading to ophiorrhine A, which could be converted to an unnatural product with a carbazole skeleton. We have investigated the total synthesis of pestalustaine A, a sesquiterpenoid which was isolated from an endophytic fungus pestalotiopsis adusta. We performed a ring expansion of a 6-membered intermediated to form the 7-membered core, a ring closing metathesis of a diene to construct the bridged 7/7 skeleton, and an intramolecular 1,4 addition to yield the pivotal tricyclic 7/5/6 framework. Through X-ray diffraction analysis of a crystal of an intermediate with the 7/5/6 core, we discovered that our structure differs from the one proposed in the isolation publication. By analyzing the spectra of the isolated natural product, we thought that the authors might have misassigned the structure
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Chan, Hsiu-Hui, e 湛琇惠. "The Constituents of Ophiorrhiza hayatana Ohwi". Thesis, 2005. http://ndltd.ncl.edu.tw/handle/19915996522280002423.

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Abstract (sommario):
碩士
國立成功大學
化學系碩博士班
93
A series of chromatographic separation has led to the isolation of fifty-four compounds from the methanol extract of Ophiorrhiza hayatana Ohwi. Among these isolates, forty compounds were characterized by comprehensive analyses of their 1D and 2D NMR and mass spectral data, and some of them were also supported by chemical transformation studies. They include fifteen alkaloids, namely harman (1), norharman (2), 6-hydroxyharmane (3), pumiloside (7), strictosamide (24), lyalosidic acid (30), strictosidinic acid (32), 9H-b-carboline-1-carboxylic acid (81), 1-methoxycarbonyl-b- carboline (82), ophiohayatine-A (83), 1-methyl-9-carboline-3-carboxylic acid (84), maxonine (85), lyaloside (86), desoxycordifolinic acid (87), vincoside (88), eight anthraquinones namely rubiadin (43) , ophiohayatone-C (89), rubiadin-3-O-b-primeveroside (90), ophiohayatone-D (91), 2-hydroxymethyl-3-methoxyanthraquinone (92), ophiohayatone-A (93), ophiohayatone-B (94), 1-hydroxy-2-hydroxymethyl-anthraquinone-3-O-b-glucoside (95), eight benzenoids, namely methyl p-hydroxycinnamate (98), methyl apraben (99), vanillin (100), ophiorridin-C (101), p-hydroxybenzaldehyde (102), ophiorridin-A (103), nonadecyl ferulate (105), ophiorridin-B (104), two coumarins, namely scopoletin (96), umbelliferone (97), four chlorophylls, namely 132-hydroxy-(132-R)-phaeophytin-a (106), aristophyll-c (107), methyl (10S)-hydroxypheophorbide-a (108), 132-hydroxy-(132-S)-phaeophytin-a (109), and three miscellaneous compounds, ursolic acid (73), adenine (110), nicotinamide (111). Among them, three compounds (91), (93), (94), (103) were new compounds, and (83), (89), (101), (104) were reported for the first time from the natural sources.
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袁淵傑. "The Constituents of the Ophiorrhiza Liukiuensus Hay". Thesis, 1995. http://ndltd.ncl.edu.tw/handle/71119265548801096826.

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Abstract (sommario):
碩士
國立成功大學
化學學系
83
Fraction and chromatography of the methanoi extract of phiorrhiza liukiuensis Hayata afforded eleven new compounds: ophiorrhizine-A, ophion-hizine-B , ophiorrhizol A, ophiorrhisin A, ophiorrhizinone-A , -Ba, -Bb , -C, -D , -E and sodium chlorogenate together with thirty seven known compounds : 1-hydroxy-2-methylanthraqumone,2-hydroxy-3-methylanthraquinone , 1-hy-droxy-3-methylanthraquinone, 1,3-dihydroxy-2-methoxymethyleneanthraqui-none, 1,6-dihydroxy-3-methylanthraquinone(or 1,7-dihydroxy-3-methylanthra-quinone), rabiadin, soranjidiol-1-methyl ether, 2-methyl-1,3,7trihydroxyanthra-quinone,2-niethyl-1,3,6-trihydroxyanthraquinone,2,8-dihydroxyl,3-dimethoxy--7-methylanthraquinone, 8-hydroxy-3-methoxy-7-methyl-1,2-methylenedioxy-anthraquinone, 1,3-dihydroxy-2,5-dimethoxy-6-methylanthraquinone, methyl 4-hydroxy-3-methoxycinnamate, vanillic acid, isovanillic acid, p-hydroxybenz-aldehyde, vanillin, protocatechuic acid, methyl p-hydroxycinnamate, ferulic acid methyl chlorogenate, quinic acid -3,4-di-O-caffeate, quinic acid -3,5-di-O-caffeate, isoscopoletin, aesculetin, socopolin, myo-inositol, quercetin 3-O-galactoside, sweroside, harman, adenine, 9-glucopyranosyl-4,7(E)-megastigma-dien-3-one, norharman, pumiloside, strictosamide, lyaloside acid, ursolic acid. The structure of these compounds were elucidated by spectroscopic and chem-ical methods. Moreover, the biological activity of these compounds are current-ly under investigation.
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Capitoli di libri sul tema "Ophiorrhine A"

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Khare, C. P. "Ophiorrhiza mungos Linn." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1096.

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Mahendran, Ganesan, e Laiq ur Rahman. "Biosynthesis and Biotechnological Production of Anticancer Drug Camptothecin in Genus Ophiorrhiza". In Reference Series in Phytochemistry, 903–20. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30185-9_32.

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Mahendran, Ganesan, e Laiq ur Rahman. "Biosynthesis and Biotechnological Production of Anticancer Drug Camptothecin in Genus Ophiorrhiza". In Reference Series in Phytochemistry, 1–18. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-11253-0_32-1.

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Asano, Takashi, Hiroshi Sudo, Mami Yamazaki e Kazuki Saito. "Camptothecin Production by In Vitro Cultures and Plant Regeneration in Ophiorrhiza Species". In Methods in Molecular Biology, 337–45. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-287-2_27.

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Preethamol, S. N., e John E. Thoppil. "Secondary Metabolites in Ophiorrhiza brunonis Wight & Arn. (Rubiaceae): A Lead Towards Its Anticancer Potential". In Bioprospecting of Tropical Medicinal Plants, 727–38. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-28780-0_29.

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Wetterauer, B., E. Wildi e M. Wink. "Production of the Anticancer Compound Camptothecin in Root and Hairy Root Cultures of Ophiorrhiza mungos L." In Biotechnological Approaches for Medicinal and Aromatic Plants, 303–41. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-0535-1_14.

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Wetterauer, Bernhard, Eric Hummel, Steffen Walczak, Melanie Distl, Markus Langhans, Pille Wetterauer, Frank Sporer, Eckhart Wildi e Michael Wink. "Physiology of Camptothecin Synthesis in Plants and Root Organ Cultures of Ophiorrhiza mungos L. and Its Production in Root Fermenters". In Exploring Plant Cells for the Production of Compounds of Interest, 291–338. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-58271-5_11.

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Atti di convegni sul tema "Ophiorrhine A"

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NABATOV, A. A., e I. A. SCHANZER. "PHYLOGENY OF OPHIORRHIZA L. ( RUBIACEAE) SPECIES FROM SOUTH-EAST ASIA REVEALED BY MOLECULAR DATA". In 5TH MOSCOW INTERNATIONAL CONFERENCE "MOLECULAR PHYLOGENETICSAND BIODIVERSITY BIOBANKING". TORUS PRESS, 2018. http://dx.doi.org/10.30826/molphy2018-31.

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