Letteratura scientifica selezionata sul tema "Odorant/xenobiotic metabolism"
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Articoli di riviste sul tema "Odorant/xenobiotic metabolism"
Rogers, M. E., M. K. Jani e R. G. Vogt. "An olfactory-specific glutathione-S-transferase in the sphinx moth Manduca sexta". Journal of Experimental Biology 202, n. 12 (15 giugno 1999): 1625–37. http://dx.doi.org/10.1242/jeb.202.12.1625.
Testo completoBoichot, Valentin, Franck Menetrier, Jean-Michel Saliou, Frederic Lirussi, Francis Canon, Mireille Folia, Jean-Marie Heydel et al. "Characterization of human oxidoreductases involved in aldehyde odorant metabolism". Scientific Reports 13, n. 1 (25 marzo 2023). http://dx.doi.org/10.1038/s41598-023-31769-4.
Testo completoShirai, Tomohiro, Dan Takase, Junkichi Yokoyama, Kuniyuki Nakanishi, Chisaki Uehara, Naoko Saito, Aya Kato-Namba e Keiichi Yoshikawa. "Functions of human olfactory mucus and age-dependent changes". Scientific Reports 13, n. 1 (18 gennaio 2023). http://dx.doi.org/10.1038/s41598-023-27937-1.
Testo completoGodoy, Ricardo, Ana Mutis, Leonela Carabajal Paladino e Herbert Venthur. "Genome-Wide Identification of Aldehyde Oxidase Genes in Moths and Butterflies Suggests New Insights Into Their Function as Odorant-Degrading Enzymes". Frontiers in Ecology and Evolution 10 (8 febbraio 2022). http://dx.doi.org/10.3389/fevo.2022.823119.
Testo completoYang, An-Jin, Ning-Na Yin, Dan-Lu Chen, Yu-Ruo Guo, Yu-Jie Zhao e Nai-Yong Liu. "Identification and characterization of candidate detoxification genes in Pharsalia antennata Gahan (Coleoptera: Cerambycidae)". Frontiers in Physiology 13 (16 settembre 2022). http://dx.doi.org/10.3389/fphys.2022.1015793.
Testo completoTesi sul tema "Odorant/xenobiotic metabolism"
Mérignac-Lacombe, Jeanne. "Approches innovantes dans la caractérisation des enzymes du métabolisme des xénobiotiques dans les muqueuses nasales : du modèle animal à l’ingénierie tissulaire". Electronic Thesis or Diss., Bourgogne Franche-Comté, 2024. http://www.theses.fr/2024UBFCI003.
Testo completoOur sensitive olfaction relies on Xenobiotic Metabolizing Enzymes (XMEs) that protect the nasal tissue from potentially harmful volatile compounds, but also quickly terminate the olfactory signal to prepare olfactory receptors to detect new odorant stimuli. Some of them also generate metabolites that participate in the odorant signal, hence their other name Odorant Metabolizing Enzymes (OMEs). The objective of this thesis was to study the nasal XMEs using two innovative models that aim to comply as much as possible with the 3R principles (Replacement, Reduction, and Refinement of animal experiments). While rat olfactory explants showed some limitations in investigating XME gene expression, human nasal respiratory mucosa tissue models were promising in vitro tools for the odorant metabolism field. These models express around 80 XME isoforms and efflux transporters. Selected XME genes were not regulated by the compounds chosen for the thesis, however, they were able to metabolize odorants, such as benzaldehyde and 3,4-hexanedione. Overall, protocols were created and adapted to use tissue models to study the implication of the respiratory epithelium in odorant metabolism in humans. This work provides novel knowledge on the involvement of the human respiratory tissue in odorant metabolism and contributes to the reduction of animal experiments