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Tesi sul tema "Neurotransmitters"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 25 luglio 2025

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1

Chao, Chih-Kai. "The vesicular glutamate transporter (VGLUT) heterologous expression, proteoliposome, computational and mass spectral studies /." CONNECT TO THIS TITLE ONLINE, 2008. http://etd.lib.umt.edu/theses/available/etd-12112008-140102/.

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2

El-Bakri, Nahid Karrar. "Estrogen effects on different neurotransmitters in rat hippocampus: implications for cognitive function /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-118-0/.

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3

Kuo, Sheng-Wen. "Synaptic protein profiles and neurotransmitter release in relation to alcoholism /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18653.pdf.

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4

Worthington, Rebecca A. (Ann). "Structure-function studies of P2X receptors." Thesis, The University of Sydney, 2001. https://hdl.handle.net/2123/27719.

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Abstract (sommario):

P2X receptors are fast, ATP-gated cation ion channels. To date seven subtypes of P2X receptors have been cloned and identified, PZXH. The membrane topology of the P2X subunit consists of intracellular amino- and carboxy-termini, two transmembrane spanning domains and a large extracellular loop. Despite similar membrane topology, within this family of receptors the P2X subtypes possess different functional characteristics. They exhibit different sensitivities to agonists and antagonists, are modulated differently by extracellular ions, and have different pore forming abilities. The region

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5

Butz, Patrick. "Structure and spectroscopy of neurotransmitters." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398069.

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6

Bagale, Sharanappa Maduraya. "Synthesis of Fluorescent Analogs of Neurotransmitters." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_theses/241.

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Abstract (sommario):

Fluorescent analogs of biomolecules have been known as useful probes to study the structure, conformations and dynamics of cellular processes. These probes are more ideal than fluorescent labeled probes, as fluorescent analog probes retain the shape, size, conformation, and recognition element of the natural substrate, while giving useful intracellular information about detection and dynamics of biomolecules. The monoamine neurotransmitters control the central and periphery nervous systems. Serotonin (5-HT), in particular, is a versatile chemical messenger responsible for a multitude of biolog

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7

Wall, Philippa Mary. "Food, hormones and neurotransmitters : three studies." Thesis, The University of Sydney, 1991. https://hdl.handle.net/2123/26331.

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Three studies on the relationship between food, hormones and neurotransmitters are presented for this thesis. In the ﬁrst study, a series of three experiments was conducted in 33 healthy human ratio volunteers. The aim was to investigate the effect of carbohydrate meals on the plasma of tryptophan (trp) to the sum of 5 other large neutral amino acids (LNAAs ) (trp: LNAA ratio). Synthesis s of serotonin, the brain neurotransmitter, depends on availability of its precursor trp from the bloodstream. Animal models have shown that the plasma trp:LNAA ratio, provides an index of trp uptake by the

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8

Newell, Kelly. "Neurotransmitter receptor binding in the posterior cingulate cortex in schizophrenia and in the phencyclidine mouse model an exploration of the NMDA hypofunction hypothesis of schizophrenia /." Access electronically, 2007. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20070905.165327/index.html.

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9

Jovanovi´c, Ksenija. "Neural circuitry and neurotransmitters underlying vertebrate walking." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0031/NQ46859.pdf.

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10

Jonsson, Amanda. "Organic electronics for precise delivery of neurotransmitters." Doctoral thesis, Linköpings universitet, Fysik och elektroteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-133164.

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Abstract (sommario):

Organic electronic materials, that is, carbon-based compounds that conduct electricity, have emerged as candidates for improving the interface between conventional electronics and biological systems. The softness of these materials matches the elasticity of biological tissue better than conventional electronic conductors, allowing better contact to tissue, and the mixed ionic-electronic conductivity can improve the signal transduction between electronic devices and electrically excitable cells. This improved communication between electronics and tissue can significantly enhance, for example, e

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11

Oni, Joshua Idowu. "Detection of neurotransmitters using metallophthalocyanines as electrocatalysts." Thesis, Rhodes University, 2002. http://hdl.handle.net/10962/d1007470.

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Some metallophthalocyanine complexes were synthesized and their catalytic activities towards the detection and quantification of the neurotransmitters dopamine, serotonin and histamine were investigated. The study of the possible interaction between these transmitter substances and the metallophthalocyanine complexes was undertaken. Dopamine, serotonin and histamine formed complexes with Iron (II) tetrasulfophthalocyanine. The rate and equilibrium constants obtained for the coordination are in the range of values reported in the literature for ligand coordination to iron phthalocyanine complex

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12

Agarwal, Shailesh Ramjilal. "Pharmacological modeling and regulation of excitatory amino acid transporters (EAATS)." CONNECT TO THIS TITLE ONLINE, 2007. http://etd.lib.umt.edu/theses/available/etd-09262007-111510/.

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13

Smith, Justin R. Ewing Andrew Graham. "Analysis of biogenic amine neurotransmitters with capillary electrophoresis." [University Park, Pa.] : Pennsylvania State University, 2009. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-4415/index.html.

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14

Kwon, Young Ha 1962. "Functional role of neurotransmitters in the visual thalamus." Thesis, Massachusetts Institute of Technology, 1991. http://hdl.handle.net/1721.1/13524.

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15

Moutinho, Daniela Mesquita. "Human ceruloplasmin and neurotransmitters: complex stabilization and crystallization." Master's thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/10853.

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Dissertation to obtain a Master Degree in Molecular Genetics and Biomedicine at Faculty of Sciences and Technology,Universidade Nova de Lisboa<br>Human ceruloplasmin (hCp) is the molecular linker between the copper and iron metabolism and its importance in the homeostasis of human body has been implied in some neurological diseases. This plasma cuproenzyme has ferroxidase activity, oxidizing Fe2+ to Fe3+ and incorporating it into apotransferrin. hCp also has aminoxidase activity regulating the levels of amine stress hormones in the bloodstream and brain. Thus, it is thought to have an import

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16

Cox, Juliette. "Tetrahydrobiopterin metabolism, neurotransmitters and behaviour in the rat." Thesis, Aston University, 1989. http://publications.aston.ac.uk/12527/.

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Various neurotoxins were investigated to assess their suitability for developing an animal model to study partial brain BH4 deficiency, neurotransmitters and behavioural alterations. Acute dosing with lead, diethylstilboestrol (DES), amphetamine and scopolamine produced no significant changes in rat brain BH4 metabolism though total biopterins in the liver were significantly reduced by lead and DES. Acute starvation of adult rats decreased brain biopterins. This loss of biopterins may be due to enhanced oxidative catabolism of the active cofactor caused by glutathione depletion. Dietary admini

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17

Gagneux, Théo. "Functional description of cerebellar networks using caged neurotransmitters." Electronic Thesis or Diss., Strasbourg, 2023. http://www.theses.fr/2023STRAJ131.

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Le cervelet coordonne les mouvements et est divisé en modules anatomo-fonctionnels traitant les informations sensorimotrices provenant d'une partie du corps. Les fibres moussues transmettent ces informations vers des cellules granulaires (GC) contactant des cellules de Purkinje (PC) de divers modules. Cette communication intermodulaire contrôle la coordination motrice. Nous avons montré que la connectivité synaptique au niveau des synapses GC-PC et GC-interneurones est conservée entre individus, mais que les traits comportementaux individuels peuvent être codés par des cartes synaptiques indiv

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18

Kim, David K. "Regulation of neurotransmitter release by calcium /." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16429.pdf.

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19

Deterding, Todd Andrew. "Radiation dosimetry of dopamine transporter ligand 2 β-carbomethoxy-3 β-(4-chlorophenyl)-8-(-2-fluoroethyl)nortropane ([¹⁸F]FECNT)". Thesis, Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/17621.

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20

Bacon, Gregory. "The anatomical basis for 5-HT-dopamine interactions in the rat substantia nigra and ventral tegmental area." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249483.

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21

Arasteh, Abdolvahab Vahabzadeh. "In vivo monitoring of the responses to stress of the noradrenergic and serotonergic projections to the rat hippocampus." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334994.

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22

Elrick, Donald Brown. "Depolarisation-secretion coupling in postganglionic sympathetic nerve terminals." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260116.

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23

Muldoon, Owen Terence. "The role of old and new local anaesthetics in postoperative pain relief." Thesis, Queen's University Belfast, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263347.

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24

Quinn, James Patrick. "Studies on the nervous system of Nereis virens." Thesis, Queen's University Belfast, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286828.

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25

Thompson, Sally-Anne. "Pharmacological properties of recombinant human GABAâ†A receptors." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272213.

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26

East, Stephen James. "Glutamate receptors and nitric oxide production in the cerebellum and hippocampus of the rat." Thesis, University of Liverpool, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357369.

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27

Daisley, Jonathan Niall. "The effects of passive avoidance learning on the release of amino acids and other putative transmitters in the forebrain of the day-old chick." Thesis, Open University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308148.

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28

Stacey, Anne Elizabeth. "Modulation of GABA and glutamate release by neurokinins in the entorhinal cortex." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269259.

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29

Wall, Mark John. "Modulation of the swimming motor pattern in Xenopus embryos of GABAâ†B receptors and by direct reduction of potassium currents." Thesis, University of Bristol, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358228.

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30

Hutton, Michael Leslie. "Molecular biology of GABA and L-glutamate receptors in the mollusc Lymnaea stagnalis." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308303.

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31

Suidan, Hana S. "Regulation of cyclic AMP metabolism in cultured sympathetic neurons." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333392.

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32

Hilton, Mark Christopher. "Intrinsic and extrinsic factors involved in the axonal growth rate of embryonic neurons." Thesis, University of St Andrews, 1999. http://hdl.handle.net/10023/14776.

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Abstract (sommario):

The main aim of this project has been to study the extrinsic and intrinsic factors involved in the axonal growth rate of sensory and sympathetic neurons during the early stages of their development. Using in vitro assays it was shown that Hepatocyte Growth Factor (HGF)/Met signalling significantly enhanced the survival and neurite length of early DRG neurons grown in the presence of NGF. This synergism was specific for NGF but not for the related neurotrophins BDNF or NT-3 (Maina et al., 1997). HGF/Met signalling was also shown to accelerate the differentiation of sympathetic neurons as well a

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33

Wafford, Keith Allan. "Receptors for amino acid neurotransmitters in the insect CNS." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330264.

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34

Huria, Tahani Rajeb Almesmary Mohamed. "Ischaemia and neurotransmitters in mature and immature white matter." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/28523.

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Optic nerves are an appropriate and widely employed model used to study the function and the pathophysiology of central white matter. This thesis investigates ischaemic injury mechanisms in mature and immature white matter, using isolated adult and neonatal Wistar rat and balb-c mouse optic nerve. A central theme to this work is that both myelinated and nonmyelinated central white matter injury is a partially glutamate-dependent process. Electrophysiology was used to record the compound action potential (CAP) under normal and pathological conditions in both myelinated and premyelinated (post-n

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35

Hampson, Laura Jane. "Control of hepatocyte glucose metabolism by hormones & neurotransmitters." Thesis, University of Newcastle Upon Tyne, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438399.

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36

Allcorn, Suzette. "Neurotransmitters and the development of the embryonic chick retina." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309514.

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37

Bouchenafa, Ouahiba. "Structural aspects of neurotransmitters in the sheep spinal cord." Thesis, University of Bristol, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338151.

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38

Jha, Amrita. "Electronic Structure Based Classification of Neurotransmitters and Related Drugs." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2284.

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Abstract (sommario):

A fundamental understanding of the relationship between structure and activity of neurotransmitters in the human brain is of vital importance for the design targeted drugs. Using density functional theory and hybrid exchange correlation energy functionals we have studied the structure-activity-relationships of some important neurotransmitters and selected drugs by calculating their absolute hardness (η) and absolute electronegativity (χ). A plot of the η- χ diagram allowed us to assign them into three distinct groups, namely, (i) Acetylcholine analogs (positively charged structure), (ii) GABA

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39

Jordan, Russell S. (Russell Stall). "Investigation of Inhibitory Influences in Neuronal Monolayer Networks Cultured from Mouse Spinal Cord." Thesis, University of North Texas, 1992. https://digital.library.unt.edu/ark:/67531/metadc500431/.

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The effects of the inhibitory neurotransmitters gammaamino butyric acid (GABA) and glycine were characterized on spontaneous activity recorded from mouse spinal cord cultures. The GABA concentration which completely inhibited burst activity was chosen as a quantifiable measure of culture drug response and was used to 1) assess interculture and intraculture variability, 2) determine the influence of culture age and initial activity on GABA responses, and 3) compare the GABA responses between networks obtained from whole spinal cord and ventral half spinal cord. Results showed that 1) no signifi

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40

Richmond, Saul Alexander. "Characterization of excitatory amino acid receptors in the mammalian central nervous system." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308536.

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41

Smith, Adam Luke. "Characterization of excitatory amino acid receptors using novel structural analogues." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302953.

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42

Khairy, Hesham A. "Modulation of anandamide actions on the neonatal rat cultured sensory neurone." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=158296.

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The possible role of L-serine as an allosteric modulator of anandamide (AEA) action on cannabinoid receptors has been investigated along with the studying the actions of AEA metabolite, ethanolamine. Dorsal root ganglia (DRG) neurons from neonate Sprague Dawley rats were used in primary culture. L-serine was found to modulate anandamide actions on overall neuronal excitability, voltage-activated K<sup>+</sup> and Ca<sup>2+</sup> currents and intracellular Ca<sup>2+</sup> flux. These modulations were suggested to be mediated via allosteric modulation of AEA actions at CB1 receptors. These ob

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43

Cirone, Jennifer. "Modulation of visual processing in the rat superior colliculus by metabotropic glutamate receptors." Thesis, University College London (University of London), 2001. http://discovery.ucl.ac.uk/1355096/.

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Abstract (sommario):

Neurones in the superficial layers of the superior colliculus (SSC) respond to novel visual events. Cells in the SSC project via neurones in the deep layer of the superior colliculus to motor nuclei which generate appropriate behavioural and avoidance responses to novel sensory stimuli. Glutamate is a neurotransmitter at the retino-collicular and cortico-collicular synapse. Glutamate receptors can be classified as either ionotropic or metabotropic (mGluRs). At present, 8 mGluRs have been cloned (mGluRI - mGluR8), and these can be divided into 3 groups based on sequence homology, pharmacology a

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44

Fraser, Caroline Margaret. "Effects of antiepileptic drugs in rodent and human astrocyte cultures, rodent brain and pentylenetetrazol-induced seizures in mice." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301809.

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45

Ross, Fiona M. "The modulation of epileptiform activity in rat hippocampal slices by adenine nucleotides." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284702.

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46

McGregor, Ailsa L. "Evaluation of a novel non-competitive antagonist as a radioligand for the N-methyl-D-aspartate receptor-channel complex in vivo." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244363.

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47

Dryden, Simon. "Neuropeptide Y and serotonin in the rat hypothalamus : interactions and the control of energy homoeostasis." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262333.

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48

Goodwin, Frank. "Investigation of 5-hydroxytryptamine, acetylcholine, octopamine and peptide receptor types using preparations of Helix aspersa pharyngeal retractor muscle (PRM) and heart." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298115.

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49

Zhang, Li Ping. "Investigations of C-FOS expression in rat spinal cord in vitro." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242708.

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50

Lalies, Margaret D. M. "Neurochemical studies of α2-adrenoceptor and imidazoline-2 binding site function in rat brain". Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285816.

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