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Articoli di riviste sul tema "Nelumbo nucifera"

1

Durairaj, Brindha, e Arthi Dorai. "Antiplatelet activity of white and pink Nelumbo nucifera Gaertn flowers". Brazilian Journal of Pharmaceutical Sciences 46, n. 3 (settembre 2010): 579–83. http://dx.doi.org/10.1590/s1984-82502010000300023.

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Abstract (sommario):
Nelumbo nucifera Gaertn (Nelumbonaceae) a plant used in Ayurvedic medicine (common name: lotus), is a perennial, large and rhizomatous aquatic herb most prevalent in South India. Preliminary phytochemical screening of both white and pink Nelumbo nucifera flowers revealed the presence of phytochemical constituents (flavonoids, alkaloids, phenols etc,). Hence, an attempt has been made to screen the effect of Nelumbo nucifera flowers (both types) on platelet aggregation. The antiplatelet activity of hydroethanolic extract of both types of flowers was studied using platelet-rich plasma in different concentrations (100-500µg/ml). Both white and pink Nelumbo nucifera flower extracts showed dose-dependent effective antiplatelet activity with maximum activity at 500µg/ml concentration; prevention of platelet aggregation was 50% of that achieved with standard aspirin. Furthermore, the antiplatelet activity of white flowers was relatively high (p<0.05; ANOVA) compared to pink flowers. In conclusion, these observations suggest that both varieties of Nelumbo nucifera flower extracts exert different levels of inhibitory action on platelets in vitro (secretion and platelet aggregation suppression) due to differences in phytochemical content (alkaloids, flavonoids, phenols, tannins, phytosteroids, glycosides and saponins).
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Dubey, Seema, e Shailbala Singh Baghel. "Phytochemical investigation and determination of phytoconstituents in flower extract of Nelumbo nucifera". Journal of Drug Delivery and Therapeutics 9, n. 1 (15 gennaio 2019): 146–49. http://dx.doi.org/10.22270/jddt.v9i1.2197.

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Abstract (sommario):
The aim of this study seeks to investigate the presence of qualitative and quantitative analysis of phytoconstituents of the flower of the plant Nelumbo nucifera. The present study provides evidence that successive solvent extract of Nelumbo nucifera contains medicinally important bioactive compounds and this justifies the use of plant species as traditional medicine for treatment of various diseases. Maximum phenolic and flavanoid content was observed in ethanolic extract of Nelumbo nucifera. The DPPH scavenging potential of the ethanolic extracts of the herbs ranged from 33%-55%. In the present study analysis of free radical scavenging activity and total phenolic and flavonoid content showed that mainly the ethanolic extract of flower extract can be the potent source of natural antioxidants. Keywords: Phytochemical, Ethanolic extract, Antioxidant activity, Nelumbo nucifera
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Hassan, Md Abul, Md Almujaddade Alfasane e Mohammad Zashim Uddin. "Taxonomic notes on Nelumbo Adans. with a new cultivar ‘Gomoti’ from Bangladesh". Bangladesh Journal of Plant Taxonomy 27, n. 2 (11 dicembre 2020): 225–31. http://dx.doi.org/10.3329/bjpt.v27i2.50663.

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Living specimens of three colour forms (pink, white and yellowish white) of Nelumbo nucifera Gaertn. were observed in different natural habitats of Bangladesh and collected. Fresh specimens were studied in the field as well as in the laboratory. After detailed study it was concluded that the three colour forms available in Bangladesh belong to the same species, Nelumbo nucifera Gaertn. However, the yellowish white colour form, having many stamens petaloid, is considered as a new cultivar Nelumbo nucifera ‘Gomoti’ and reported here as the first lotus cultivar from Bangladesh. Bangladesh J. Plant Taxon. 27(2): 225-231, 2020 (December)
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Bibi, Sagheera, e Lubna Naz. "The therapeutic potential of Nelumbo Nucifera against oxidative damage induced by Carbon Tetrachloride in rats." International Journal of Endorsing Health Science Research (IJEHSR) 10, n. 2 (25 maggio 2022): 213–19. http://dx.doi.org/10.29052/ijehsr.v10.i2.2022.213-219.

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Abstract (sommario):
Background: Herbal treatment has paid much attention in the world over the past decades. Nelumbo nucifera is used all over the world as a medicinal plant. It is an aquatic perennial plant belonging to the Nelumbonaceae family. The protective effects of Nelumbo nucifera are due to the active ingredients present in it. The study was conducted to evaluate the protective effects of Nelumbo nucifera seeds against hepatotoxicity caused by carbon tetrachloride (CCl4) in rats. Methodology: Eighteen Wistar Albino rats were allotted into three groups (n=6), control group, CCl4 treated group given CCl4 0.8 ml/kg body weight subcutaneously twice a week, CCl4 + N. Nucifera treated group given CCl4 0.8 ml/kg body weight 2 times a week subcutaneously and also given Nelumbo nucifera extract (200 mg/kg body weight) orally through gavage daily. After 28 days of the experiment, serum samples were taken for estimation of enzyme activities and liver tissue samples were collected for evaluation of antioxidant enzyme levels. Results: It was observed that liver weight increased in the CCl4 treated group while liver weight decreased in CCl4 + N. Nucifera treated group. CCl4 administration significantly raises the transaminase levels such as Aspartate transaminase (AST) (p<0.01), Aspartate transaminase (ALT) (p<0.05), and Alkaline phosphatase (ALP) (p<0.05) whereas CCl4 + N. Nucifera treated group serum transaminases are reduced. Antioxidant activities such as Catalase (p>0.05), Glutathione (GSH) (p>0.05) and Superoxide dismutase (SOD) (p=0.05) decreased in the CCl4 treated group. Significant elevation of antioxidant enzymes; Catalase (p<0.05), GSH (p<0.05) and SOD (p>0.05) in CCl4 + N. Nucifera treated group. Serum Malondialdehyde (MDA) concentration (p<0.05) significantly raised in the CCl4 hepatotoxic group compared to the control group. A decreased MDA levels were observed in the CCl4 + N. Nucifera treated group, indicating its potential to counteract the harmful effects of CCl4. Conclusion: This study suggests that Nelumbo nucifera seeds have overcome CCl4-induced hepatotoxicity by their antioxidant effects.
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Bhardwaj, Alok, e Ketan P. Modi. "PHARMACOGNOSTICAL SCREENING AND DETERMINATION OF ANTIOXIDANT ACTIVITY OF NELUMBO NUCIFERA GAERTN ETHANOL SEED EXTRACT BY DIFFERENT IN VITRO MODELS". International Journal of Pharmacy and Pharmaceutical Sciences 9, n. 3 (3 febbraio 2017): 64. http://dx.doi.org/10.22159/ijpps.2017v9i3.16362.

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Objective: To perform the pharmacognostical screening and determination of antioxidant activity of Nelumbo nucifera Gaertn ethanol seed extract by different in vitro models.Methods: The different pharmacognostical parameters were evaluated as per standard protocols with some modifications. The various concentrations of ethanol seed extract of Nelumbo nucifera were evaluated for antioxidant activity using the standard in vitro methods like hydrogen peroxide (H2O2) scavenging assay, nitric oxide (NO) radical scavenging assay, reducing power capacity assessment, β-Carotene bleaching assay, ferric thiocyanate method (FTC) and thiobarbituric acid (TBA) assay.Results: Extractive values, ash values and moisture content values of Nelumbo nucifera were found to be as per the IP 2007 and Ayurvedic pharmacopoeia standard. Among the four extracts viz. Petroleum ether, chloroform, ethanol and aqueous, the ethanol extract showed significant antioxidant activity. The ethanol seed extract of Nelumbo nucifera (NNSE) exhibited high antioxidant activity (IC50 = 12.65 µg/ml) in 1, 1-diphenyl-2-picryldydrazyl (DPPH) radical scavenging assay. In FTC method the absorbance of NNSE increased slowly, which shows strong antioxidant ability. The thin layer chromatography (TLC) of the extract revealed 6 spots with the Rf values 0.41, 0.47, 0.59, 0.65, 0.67, 0.74 with the solvent system of toluene: ethyl acetate: formic acid (5:4:0.5, v/v/v). The high-performance thin layer chromatography (HPTLC) revealed the spots at Rf values 0.65 and 0.68. These fractions obtained by preparative TLC also confirmed the same. Conclusion: The present investigation suggested that the NNSE has significant antioxidant activity. These results clearly indicate that Nelumbo nucifera is effective against free radical mediated diseases, thus replacing the synthetic ones.
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Pengon, Sirikarn, Nawinda Chinatangkul, Chutima Limmatvapirat e Sontaya Limmatvapirat. "Development of Antimicrobial Nanoemulsions Containing Nelumbo nucifera Extract". Key Engineering Materials 859 (agosto 2020): 226–31. http://dx.doi.org/10.4028/www.scientific.net/kem.859.226.

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Abstract (sommario):
Nelumbo nucifera is a medicinal herb widely distributed in Thailand which possesses its antioxidant and antimicrobial activities. The aims of this study were to investigate the antimicrobial effects and to develop the formulations containing Nelumbo nucifera crude extracts. The crude extracts of each part of the plants, petals, pollens, receptacles and stalks were separately obtained using 95% w/w ethyl alcohol and then subjected to the phytochemical studies. The total phenolic content was quantified by using Folin-ciocalteu colorimetric method, and the antibacterial features against Staphylococcus aureus was also evaluated. The nanoemulsions incorporated with Nelumbo nucifera crude extracts were thereafter formulated. The results showed that saponins, terpenoids, flavonoids and coumarins found in petals was 184.30 ± 0.50 mg GAE/g total phenolic content which was 4-fold higher than those found in the other part of the plants. Moreover, the crude extract from petals exhibited the activity against S. aureus as indicated by the minimum bactericidal concentration (MBC) of 100 mg/mL. Moreover, the good stability of nanoemulsions consisting of 0.05% w/w petal extract was observed displaying a particle size of 400 ± 139 nm, a zeta potential of -8.09 ± 1.04 mV, and a pH value of 5.87 ± 0.07. Owing to the antimicrobial test against S.aureus, the inhibition percentage of nanoemulsions was 80.35 ± 0.106. Accordingly, this study provides the increasing of antimicrobial properties of Nelumbo nucifera crude extract when preparing into the nanoemulsions formulation. In addition, this finding could raise the value of Nelumbo nucifera which could be utilized as an alternative active ingredient for the treatment of skin bacterial infection.
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Itoh, Atsuko, Tomomi Saitoh, Kaori Tani, Misaki Uchigaki, Yumi Sugimoto, Jun Yamada, Hiroshi Nakajima, Hideo Ohshiro, Schujian Sun e Takao Tanahashi. "Bisbenzylisoquinoline Alkaloids from Nelumbo nucifera". CHEMICAL & PHARMACEUTICAL BULLETIN 59, n. 8 (2011): 947–51. http://dx.doi.org/10.1248/cpb.59.947.

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Schubert, Peter, Jutta Lorenz e Dirk Ullrich. "Lotosblumen (Nelumbo Adans.) im heimischen Gartenteich?" Der Palmengarten 66, n. 2 (4 giugno 2018): 126–35. http://dx.doi.org/10.21248/palmengarten.391.

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Abstract (sommario):
Der indische (Nelumbo nucifera) und der amerikanische Lotos (Nelumbo lutea) sind außerordentlich attraktive Wasserpflanzen. Nelumbo nucifera hat hohen Symbolwert in den südostasiatischen Kulturen, wird in Asien aber auch als Nahrungspflanze sehr geschätzt. Die Oberfläche der Blätter hat wichtige Hinweise zur Entwicklung selbstreinigender Oberflächen von Kunststoffen und Lacken geliefert. Weil für die Blütenentwicklung Sommertemperaturen über 20 °C notwendig sind, ist Lotos im Freiland mitteleuropäischer Gärten kaum zu finden. Wenn man jedoch bestimmte Kulturmaßnahmen beachtet, ist seine Freilandkultur in sommerwarmen Gebieten Deutschlands durchaus zu empfehlen. Davon konnte man sich in den letzten Jahren im Botanischen Garten in Mainz und im Palmengarten in Frankfurt überzeugen.
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Ryu, Tae-Kyeong, Eunmiri Roh, Han-Seung Shin e Jong-Eun Kim. "Inhibitory Effect of Lotusine on Solar UV-Induced Matrix Metalloproteinase-1 Expression". Plants 11, n. 6 (14 marzo 2022): 773. http://dx.doi.org/10.3390/plants11060773.

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Solar ultraviolet (sUV) radiation remains a major cause of skin aging. Nelumbo nucifera (lotus) is a well-known edible plant widely grown in Asia, including Korea, China, and Japan. The lotus consists of flowers, leaves, stems, and seeds, and all parts reportedly possess nutritional and medical values. Traditionally, lotus flowers, leaves, stems, and seeds have been used as antidiarrheal agents, diuretics, antipyretics, and antimicrobial and antihyperlipidemic agents. In addition, the Nelumbo nucifera lotus embryo has been shown to possess sedative and antipyretic properties and can relieve hemostatic thirst and treat eye diseases. Recently, Nelumbo nucifera lotus flower extract has been widely used in cosmetics due to its ability to reduce wrinkles and its whitening effects. Numerous cosmetics using Nelumbo nucifera lotus embryo extracts are commercially available. However, the active components of Nelumbo nucifera remain elusive. Lotusine is a phytochemical and soluble alkaloid found in lotus embryos. Herein, we examined the anti-wrinkle effect of lotusine using sUV-exposed human keratinocytes. We observed that lotusine reduced sUV-induced matrix metalloproteinase (MMP)-1 expression and modulated transcriptional activities of activator protein (AP)-1 and nuclear factor kappa B (NF-κB). sUV-induced AP-1 and NF-κB activity could be activated via multiple signal transduction cascades, including the p38 MAPK, JNK, ERK1/2, and Akt pathways in the skin. Lotusine inhibited the MEK1/2-ERK1/2-p90RSK, MKK3/6-p38, and Akt-p70S6K pathways. Overall, our findings suggest that lotusine has potential benefits related to MMP-1 expression and skin aging following sUV exposure. Hence, the lotus can be developed as a valuable functional food and cosmetic material.
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Bhardwaj, Alok, e Ketan P. Modi. "ANTIDIABETIC AND ANTIHYPERLIPIDAEMIC ACTIVITY OF NELUMBO NUCIFERA GAERTN ETHANOL SEED EXTRACT IN STREPTOZOTOCIN INDUCED DIABETIC RATS". International Journal of Pharmacy and Pharmaceutical Sciences 9, n. 10 (2 ottobre 2017): 197. http://dx.doi.org/10.22159/ijpps.2017v9i10.21455.

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Objective: The main objective of the study was to investigate the effect of ethanol seed extracts of Nelumbo nucifera Gaertn (Nymphaeaceae) as antihyperglycemic, anti-hyperlipidemic and antioxidant activity in streptozotocin-induced diabetic rats.Methods: Diabetes was induced in wistar albino rats by administration of streptozotocin (single intraperitoneal dose of 60 mg/kg B. W). The ethanol extract of N. nucifera seed at a dose of 200 and 400 mg/kg body weight was administrated at a single dose per day to STZ induced diabetic rats for a period of 42 d. The different pharmacological parameters were evaluated. The effect of ethanol seed extract of N. nucifera on insulin, blood glucose, urea, creatinine, HbA1C, serum protein, albumin, globulin, serum enzymes, serum lipid profiles, lipid peroxides (LPO) and other antioxidant enzymes like catalase (CAT), glutathione peroxidase (GPx), superoxide dismutase (SOD) and reduced glutathione (GSH) were measured in the diabetic rats.Results: In the acute toxicity study ethanol seed extract of Nelumbo nucifera were non-toxic at 2000 mg/kg in rats. The ethanol extract of Nelumbo nucifera seed showed significant reduction in blood glucose (p<0.05), serum enzymes (SGPT, SGOT, ALP) (p<0.05), lipid parameters (TC, TG, VLDL, LDL) (p<0.05) except HDL and significantly increased insulin (p<0.05), HDL (p<0.05), GPx, GSH, SOD and CAT (p<0.05) at the dose of 400 mg/kg when compared with the diabetic-induced control.Conclusion: The present study suggested that the NNSE has significant (p<0.05) antihyperglycemic, antihyperlipidemic and antioxidant activity in STZ induced diabetic rats. These results clearly indicate that Nelumbo nucifera is effective against free radical-mediated diseases, thus replacing the synthetic ones.
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Tesi sul tema "Nelumbo nucifera"

1

Ming, Ray, Robert VanBuren, Yanling Liu, Mei Yang, Yuepeng Han, Lei-Ting Li, Qiong Zhang et al. "Genome of the long-living sacred lotus (Nelumbo nucifera Gaertn.)". BioMed Central, 2013. http://hdl.handle.net/10150/610151.

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BACKGROUND:Sacred lotus is a basal eudicot with agricultural, medicinal, cultural and religious importance. It was domesticated in Asia about 7,000 years ago, and cultivated for its rhizomes and seeds as a food crop. It is particularly noted for its 1,300-year seed longevity and exceptional water repellency, known as the lotus effect. The latter property is due to the nanoscopic closely packed protuberances of its self-cleaning leaf surface, which have been adapted for the manufacture of a self-cleaning industrial paint, Lotusan.RESULTS:The genome of the China Antique variety of the sacred lotus was sequenced with Illumina and 454 technologies, at respective depths of 101x and 5.2x. The final assembly has a contig N50 of 38.8 kbp and a scaffold N50 of 3.4 Mbp, and covers 86.5% of the estimated 929 Mbp total genome size. The genome notably lacks the paleo-triplication observed in other eudicots, but reveals a lineage-specific duplication. The genome has evidence of slow evolution, with a 30% slower nucleotide mutation rate than observed in grape. Comparisons of the available sequenced genomes suggest a minimum gene set for vascular plants of 4,223 genes. Strikingly, the sacred lotus has 16 COG2132 multi-copper oxidase family proteins with root-specific expression
these are involved in root meristem phosphate starvation, reflecting adaptation to limited nutrient availability in an aquatic environment.CONCLUSIONS:The slow nucleotide substitution rate makes the sacred lotus a better resource than the current standard, grape, for reconstructing the pan-eudicot genome, and should therefore accelerate comparative analysis between eudicots and monocots.
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Chen, Kuan-Ling, e 陳冠菱. "Fungi on leaves of Nelumbo nucifera Gaertn". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/8936s2.

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Abstract (sommario):
碩士
國立中央大學
生命科學系
102
Nelumbo nucifera is an herbaceous, perennial aquatic plant belonging to Nelumbonaceae (order Proteales, in the clade eudicots, genus Nelumbo), and is found in tropical and subtropical Asia. The self-cleansing property of its leaves is called lotus effect. So far, some parasitic fungi of N. nucifera have been reported, like Alternaria nelumbii, Colletotrichum gloeosporioides, Pseudocercospora nymphaeacea, but the endophytic fungi have not been recorded. The purpose of this study is to detect and identify fungi from leaves of N. nucifera including ectophytic and endophytic fungi. We collected leaves of N. nucifera at different places in Taiwan. Each leaf was divided into leaf lamina and petiole. These parts were surface-sterilized with 95% ethanol and 6% sodium hypochlorite and then rinsed in sterile water. The effectiveness of surface sterilization was verified by the imprint technique. From 1002 plant segments, 476 isolates were produced in culture, comprising 33 typical terrestrial species. Most isolates were from leaves (71%) compared to those from petiole (29%). Among ectophytic fungi, the species Pseudocercospora sp. nov. and the genus Dissoconium are recorded for Taiwan for the first time.
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Liu, Chih-Peng, e 劉志鵬. "The immunomodulatory activities of (S)-armepavine isolated from Nelumbo nucifera". Thesis, 2006. http://ndltd.ncl.edu.tw/handle/61759948796150877415.

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Abstract (sommario):
博士
國立陽明大學
藥理學研究所
94
T cell-dependent immune responses play important roles in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). Nelumbo nucifera is a useful edible and medicinal plant for the treatment of diarrhea, tissue inflammation, and hemostasis. A previous study conducted by our laboratory showed that (S)-armepavine (C19H23O3N; MW313) from N. nucifera inhibited the proliferation of human blood mononuclear cells (PBMCs) activated with phytohemagglutinin (PHA). Therefore, the present study examined the immune modulatory actions of (S)-armepavine on MRL-lpr/lpr mice in vivo and PBMCs in vitro. MRL-lpr/lpr mice treated orally with (S)-armepavine (5 or 10 mg/kg/day) for 6 weeks could prevent lymphadenopathy and elongate life span. It seemed to be mediated by inhibition of splenocytes proliferation, suppression of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10), and interferon-�� (IFN-��) genes expression, reduction of glomerular hypercellularity and immune complexes deposition, decrease of urinary protein, anti-double stranded DNA autoantibody and anti-small nuclear ribonuclear protein antibody production, and impairments of cytokines production. The in vitro results showed that (S)-armepavine (25, 50, and 100 �嵱) suppressed inducible T cells kinase and phospholipase C�� phosphorylation in a phosphoinositide 3-kinase (PI3K)-dependent manner, but (S)-armepavine had no effect on lymphocyte-specific kinase or ��-associated protein-70 phosphorylation. Through blocking the activation of PI3K, (S)-armepavine inhibited its downstream signaling such as Ca2+, protein kinase C, nuclear factor of activated T cells, nuclear factor �羠, and activator protein-1 expression in PHA-activated PBMCs. The study also showed (S)-armepavine had no direct cytotoxicity, but attenuated the mRNA and protein expression of IL-2 and IFN-��, and thereby suppressed the proliferation of PHA-activated PBMCs. By blocking cell proliferation and inflammatory mediators production of T cells, (S)-armepavine may to be developed as a potential immunosuppressive agent for the management of autoimmune disease like SLE.
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Hicks, David James, University of Western Sydney, College of Health and Science e School of Natural Sciences. "Development and evaluation of a system for the study of mineral nutrition of sacred lotus (Nelumbo nucifera)". 2005. http://handle.uws.edu.au:8081/1959.7/23184.

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Abstract (sommario):
The sacred lotus (Nelumbo nucifera) is a large aquatic plant endemic to subtropical and tropical Asia and northern Australia. Lotus has a combination of morphological and anatomical features that make it challenging for research work. The necessity of research on lotus is driven by niche market opportunities identified in Japan during counter seasonal production periods. Several features of lotus are utilised for consumer applications with commercial promise including seeds, young shoots and rhizome production. Further, the flowers and seed pods have value as cut-flower products and religious decoration. Several challenges have to be overcome before production of adequate products can be realised in Australia. The challenges which can be addressed most immediately are the questions regarding plant nutrition for lotus. In order to accomplish certain objectives, development of a system for growth and analysis of imposed nutrient treatments in replication, which accommodated a plant with unusual and seasonal attributes, was essential. The results of the tests conducted on the trialled system, whilst not conclusive, provide a solid reference for any future research on lotus nutrition. Recommendations are made for design and enhancement of the system to provide guidelines for such research.
Doctor of Philosophy (PhD)
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周聖萍. "Studies on the Storage Protein in the Seed of Nelumbo Nucifera". Thesis, 1987. http://ndltd.ncl.edu.tw/handle/60620318215966661207.

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Abstract (sommario):
碩士
國立臺灣師範大學
生物學系
75
The storage protein in the cotyledon of lotus (Nelumbo nucifera Gaertn) has been isolated by sequen-tial extraction according to the solubility of the proteins. Albumin fraction was found to be the major storage protein which constituted approximately 62% of the total protein. The glutelin fraction which was solubilized under highly denaturing condition constituted approximately 2 6% of the total protein.   The polypeptides of albumin fraction observed by SDS-PAGE electrophoresis were highly heterogeneous and composed at least seven polypeptide groups. Two polypeptide groups, 99kd and 54-59kd, were purified by ammonium sulfate fractionation and two cycles of Sephadex G-100 gel filtration. Amino acid composition of the 99kd polypeptide has been analyzed. It conteined more glutamic acid/glutamine, glycine and threonine but less aspartic acid/asparagine, isoleucine and tyrosine in compared to other proteins.   Accumulation of storage proteins in the cotyledon of developing seed was analyzed. The polypeptide groups increased gradully during early development.while a dramatic change in quantity as well as quality of teh polypeptides were observed in the seventh developing stage. the result indicates that the major storage protein is most activity synthesized during this transit period between sixth and seventh developing stages.   Storage protein in the lotus cotyledon was obviously decreased ten days after germination, which might be corresponding with the higher activity of the protease.
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Lay, Peir-Chyi, e 賴培錡. "Studies on the Antioxidant Activity Constituents of Lotus Leaf (Nelumbo nucifera Gaertner)". Thesis, 2003. http://ndltd.ncl.edu.tw/handle/83728625649094571017.

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Abstract (sommario):
碩士
靜宜大學
應用化學研究所
91
In our continuing search for natural antioxidant constituents from natural plant, was found that extracts of Nelumbo nucifera Gaertner. showed the significant antioxidant activity. In this study, the antioxidant active constituent of Nelumbo nucifera Gaertner. was isolated by the process of antioxidant activity assay and column chromato-graphy. The structure was elucidated by the spectroscopic methods and its activity was also achieved.
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Lin, Yu-Hui, e 林玉恵. "Studies on the functional compounds of Lotus (Nelumbo nucifera) and Lotus products". Thesis, 2004. http://ndltd.ncl.edu.tw/handle/26520312816381298110.

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Chu, Yu-Wei, e 朱淯維. "Studies on Antioxidation Properties of Ethanolic Extracts of Lotus Leaf (Nelumbo nucifera)". Thesis, 2003. http://ndltd.ncl.edu.tw/handle/26761528903715534952.

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Abstract (sommario):
碩士
國立臺灣大學
食品科技研究所
91
Lotus has been used as an essential material both in drugs and foods for a long time. There were many reports about its function in old Chinese traditional herb book, especially for the function of “cooling the blood” by lotus leaf. Hypertension and cardiovascular diseases which are based on atherosclerosis make many people dead in Taiwan. And a fact is made sure that hyperoxia can cause the happening of atherosclerosis. So the purpose of this study is to investigate the antioxidant effect of lotus in Taiwan. Using lotus leaf as major and other parts of lotus as minor material to find out the antioxidative potent and seek the relationship between atherosclerosis and the “cooling the blood” function of lotus leaf. The results of the experiment revealed the antioxidative potent of lotus leaf 95% ethanolic extracts(LLE) in inhibiting peroxidation of linoleic acid, scavenging effect of DPPH radical, high TEAC value, high reducing power, and increased lag phase of LDL oxidation. Except the best performance of TEAC value of lotus rhizome knot 95% ethanolic extracts, LLE showed nice effects in antioxidation and had the highest total phenol and flavonoid content in the four different parts. Extracts of lotus seed and rhizome both were poor in antioxidation aspects. And then make four different partitions of LLE with different polarity, there is a best effect from material in 1-Butanol in scavenging free radicals; and there is a best performance in delaying LDL oxidation by adding the material in ethyl acetate (LLEP2) because of high content in flavonoids. Then using silica gel to further separate the materials in LLEP2.There were 22 subfractions(A~V) getting and subfraction N, P, R have best effects in scavenging free radicals. In the peroxidation of linoleic acid, subfraction C, D, F also have good protecting capacity, and Q has the highest reducing power.P has the highest capacity of delaying LDL oxidation.
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Wen, Hsiu-Chiung, e 溫秀瓊. "Nelumbo Nucifera Leaf extract inhibits 2-acetylaminofluorene-induced hepatocellular carcinoma in rats". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/60704994518346375412.

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Weng, Ting-Chun, e 翁鼎鈞. "Studies of Nelumbo nucifera Semen and Armepavine against Hepatic Fibrosis in Rats". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/13423036470481120979.

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博士
國立陽明大學
傳統醫藥研究所
101
During prolonged liver injury, activation of hepatic stellate cells (HSCs) is crucially involved in the pathogenesis of liver fibrosis. Excessive oxidative stress, cytokines release due to hepatic inflammation and apoptotic bodies from hepatocytes are implicated in the activation of HSCs and hepatic fibrogenesis. Strategies of antioxidation, anti-inflammation and hepato-protection have been proposed to inhibit the activation of HSCs and attenuate hepatic fibrosis. Armepavine (Arm), an active component of Nelumbo nucifera Semen (Nn), has been reported to exert antioxidative, anti-inflammatory and hepatoprotective effects. This study investigated the in vitro and in vivo anti-fibrotic effects of an armepavine-enriched extract of Nn (Nelumbo nucifera Semen) and Arm. A hepatic stellate cell line of rat origin (HSC-T6), which could be activated by TNF-α, TGF-β1 or LPS was used as a cellular model, and we used extract of Nn (0-80 μg/ml) and Arm (0-10 μM) as treatments. The extract of Nn (0-80 M) inhibited TNF-α-stimulated α-SMA secretion, intracellular ROS production, and suppressed IκBα phosphorylation and NF-κB transcriptional activity induced by TNF-α. Nn (0-80 M) also inhibited mRNA expressions of fibrosis-related genes including α-SMA. Moreover, the extract of Nn (0-80 μg/ml) significantly reduced TGF-β1-induced collagen deposition, Smad 2/3 phosphorylation and α-SMA secretion. Arm was further shown to reduce TNF-α-induced expression of α-SMA and procollagen type I, intracellular ROS production, collagen deposition, NF-κB transactivation performed by the p-NF-κB-luc luciferase assay, MAPK phosphorylations including p38, ERK1/2 and JNK, translocation of transcription factors-NF-κB, JunD and C/EBPβ in HSC-T6 cells. Furthermore, Arm (10 µM) could significantly inhibit TNF-α stimulated protein in HSCs expression of angiopoietin-1 from 337 ± 24% to 242 ± 19% in HSCs. The in vitro study suggested Arm inhibited TNF-α-stimulated HSC activation MAPK phosphorylations and multiple transcription factors-NF-κB, JunD and C/EBPβ. Arm (10 µM) also significantly inhibited LPS-induced α-SMA secretion (from 174 ± 37% to 98 ± 4%) in HSCs. We induced hepatic fibrosis in rats by thioacetamide (TAA) administration and bile duct ligation (BDL), to investigate the in vivo effects of the extract of Nn and Arm on hepatic fibrosis. Both the extract of Nn 0.5 g/kg and Arm (3 and 10 mg/kg) significantly reduced the fibrosis scores of livers, levels of plasma AST and ALT activities and hepatic collagen contents. Arm (3 and 10 mg/kg) significantly reduced mRNA expression levels of IL-6, TGF-β1, TIMP-1, col1α2, iNOS, and ICAM-1 genes, but up-regulated metallothionein gene in TAA and BDL rats. Furthermore, immuno-staining results showed that α-SMA- and NF-κB- positive cells (activated HSCs) were decreased in the fibrotic livers of TAA and BDL rats treated by Arm. In conclusion, results from this study suggested that the extract of Nn and Arm exerted both in vitro and in vivo antifibrotic effects in rats, possibly through anti-NF-κB, JunD, and C/EBPβ activation pathways. The data of this study might support drug development and clinical application of Arm and Nn.
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Libri sul tema "Nelumbo nucifera"

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Lotos im alten Ägypten: Vorarbeiten zu einer Kulturgeschichte von Nymphaea lotus, Nymphaea coerulea und Nelumbo nucifera in der dynastischen Zeit. Pfaffenweiler: Centaurus-Verlagsgesellschaft, 1985.

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Tropical tuber starches: structural and functional characteristics. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781786394811.0000.

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Abstract This book chapter outlines tuber crops and their economic importance, i.e. Arracacia xanthorrhiza, Manihot esculenta, Eleocharis dulcis, Ipomoea batatas, Colocasia esculenta, Xanthosoma sagittifolium, Amorphophallus paeoniifolius, Dioscorea, Sphenostylis stenocarpa, Tacca leontopetaloides, Alocasia macrorrhizos, Solenostemon rotundifolius, Pueraria lobata, Nelumbo nucifera, Oxalis tuberose, Canna indica, Curcuma zedoaria, Cyrtosperma merkusii, Psophocarpus tetragonolobus, and Cucurbita foetidissima.
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Capitoli di libri sul tema "Nelumbo nucifera"

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Lim, T. K. "Nelumbo nucifera". In Edible Medicinal and Non-Medicinal Plants, 55–109. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26062-4_5.

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Bährle-Rapp, Marina. "Nelumbo nucifera". In Springer Lexikon Kosmetik und Körperpflege, 374. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_6897.

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Ross, Ivan A. "Nelumbo nucifera". In Medicinal Plants of the World, 353–62. Totowa, NJ: Humana Press, 2001. http://dx.doi.org/10.1007/978-1-59259-237-1_19.

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Mukherjee, Pulok K., Debayan Goswami, Bhaskar Das e Subhadip Banerjee. "Nelumbo nucifera". In Natural Medicines, 139–64. Boca Raton : Taylor & Francis, [2019]: CRC Press, 2019. http://dx.doi.org/10.1201/9781315187853-8.

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Tang, Weici, e Gerhard Eisenbrand. "Nelumbo nucifera Gaertn." In Chinese Drugs of Plant Origin, 697–701. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-73739-8_89.

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Khare, C. P. "Nelumbo nucifera Gaertn." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1060.

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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott e R. W. Briddon. "Nelumbo nucifera (Indian lotus)". In Encyclopedia of Plant Viruses and Viroids, 1593–94. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_611.

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Pandita, Anu, e Deepu Pandita. "Lotus (Nelumbo nucifera Gaertn)". In Antioxidants in Vegetables and Nuts - Properties and Health Benefits, 19–44. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-7470-2_2.

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Zhao, Xiao-liang. "Nelumbo nucifera Gaertn. 荷 (He, Lotus)". In Dietary Chinese Herbs, 731–39. Vienna: Springer Vienna, 2015. http://dx.doi.org/10.1007/978-3-211-99448-1_82.

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Sharma, S. C., e A. K. Goel. "Environmental Degradation and ex-situ Conservation of Nelumbo nucifera". In Environmental Stress: Indication, Mitigation and Eco-conservation, 405–10. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9532-2_35.

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Atti di convegni sul tema "Nelumbo nucifera"

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Cho, W.-K., H. J. Yang e J. Y. Ma. "Antiviral effect of Lotus (Nelumbo nucifera Gaertn.) Leaf Water Extract against Influenza A Virus". In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759338.

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