Letteratura scientifica selezionata sul tema "Multi-step mechanism"

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Articoli di riviste sul tema "Multi-step mechanism"

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Hammerling, Gunter J., Gunther Schonrich, Iris Ferber e Bernd Arnold. "Peripheral Tolerance as a Multi-Step Mechanism". Immunological Reviews 133, n. 1 (giugno 1993): 93–104. http://dx.doi.org/10.1111/j.1600-065x.1993.tb01511.x.

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Xiong, Shaozhuan, e Yantian Bi. "A Novel Multi-Step Global Mechanism Scheme for n-Decane Combustion". Entropy 25, n. 10 (28 settembre 2023): 1389. http://dx.doi.org/10.3390/e25101389.

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Based on the directed relation graph with error propagation (DRGEP) reduction method, a detailed mechanism consisting of 119 species and 527 reactions for n-decane was simplified. As a result, a skeletal mechanism comprising 32 species and 73 reactions was derived. Subsequently, the quasi-steady state approximation (QSSA) reduction method was employed to further simplify the skeletal mechanism, resulting in a reduced mechanism with 18 species and 14 global reactions. A comparison between the reduced mechanism, skeletal mechanism, and detailed mechanism revealed that the reduced and skeletal mechanisms successfully replicated the combustion characteristics of the detailed mechanism under a range of initial conditions. These models can be credibly incorporated into large-scale combustion simulation, serving as a solid foundation for enhancing computational efficiency.
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Tsuchiya, Hikaru, Akinori Endo e Yasushi Saeki. "Multi-Step Ubiquitin Decoding Mechanism for Proteasomal Degradation". Pharmaceuticals 13, n. 6 (23 giugno 2020): 128. http://dx.doi.org/10.3390/ph13060128.

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The 26S proteasome is a 2.5-MDa protease complex responsible for the selective and ATP-dependent degradation of ubiquitylated proteins in eukaryotic cells. Proteasome-mediated protein degradation accounts for ~70% of all cellular proteolysis under basal conditions, and thereby any dysfunction can lead to drastic changes in cell homeostasis. A major function of ubiquitylation is to target proteins for proteasomal degradation. Accompanied by deciphering the structural diversity of ubiquitin chains with eight linkages and chain lengths, the ubiquitin code for proteasomal degradation has been expanding beyond the best-characterized Lys48-linked ubiquitin chains. Whereas polyubiquitylated proteins can be directly recognized by the proteasome, in several cases, these proteins need to be extracted or segregated by the conserved ATPases associated with diverse cellular activities (AAA)-family ATPase p97/valosin-containing protein (VCP) complex and escorted to the proteasome by ubiquitin-like (UBL)–ubiquitin associated (UBA) proteins; these are called substrate-shuttling factors. Furthermore, proteasomes are highly mobile and are appropriately spatiotemporally regulated in response to different cellular environments and stresses. In this review, we highlight an emerging key link between p97, shuttling factors, and proteasome for efficient proteasomal degradation. We also present evidence that proteasome-containing nuclear foci form by liquid–liquid phase separation under acute hyperosmotic stress.
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Ran, Cai, Xinfu Li e Fang Yang. "Multi-Step Structure Image Inpainting Model with Attention Mechanism". Sensors 23, n. 4 (19 febbraio 2023): 2316. http://dx.doi.org/10.3390/s23042316.

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The proliferation of deep learning has propelled image inpainting to an important research field. Although the current image inpainting model has made remarkable achievements, the two-stage image inpainting method is easy to produce structural errors in the rough stage because of insufficient treatment of the rough inpainting stage. To address this problem, we propose a multi-step structured image inpainting model combining attention mechanisms. Different from the previous two-stage inpainting model, we divide the damaged area into four sub-areas, calculate the priority of each area according to the priority, specify the inpainting order, and complete the rough inpainting stage several times. The stability of the model is enhanced by the multi-step method. The structural attention mechanism strengthens the expression of structural features and improves the quality of structure and contour reconstruction. Experimental evaluation of benchmark data sets shows that our method effectively reduces structural errors and improves the effect of image inpainting.
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Bellat, Vanessa, Rémi Chassagnon, Olivier Heintz, Lucien Saviot, David Vandroux e Nadine Millot. "A multi-step mechanism and integrity of titanate nanoribbons". Dalton Transactions 44, n. 3 (2015): 1150–60. http://dx.doi.org/10.1039/c4dt02573c.

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Using TEM and EFTEM, we showed that titanate nanoribbons are made of an assembly of smaller ribbons juxtaposed and piled up on one another. We also studied their morphological, structural and chemical characteristics using XRD, Raman and XPS. New insights were obtained regarding their forming mechanism and structural integrity.
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Jagielski, J., e L. Thomé. "Multi-step mechanism of damage accumulation in irradiated crystals". Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 266, n. 8 (aprile 2008): 1212–15. http://dx.doi.org/10.1016/j.nimb.2007.12.097.

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Hamdi, Mohamed, Hmaeid Benticha e Mohamed Sassi. "Evaluation of reduced chemical kinetic mechanisms used for modeling mild combustion for natural gas". Thermal Science 13, n. 3 (2009): 131–37. http://dx.doi.org/10.2298/tsci0903131h.

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A numerical and parametric study was performed to evaluate the potential of reduced chemistry mechanisms to model natural gas chemistry including NOx chemistry under mild combustion mode. Two reduced mechanisms, 5-step and 9-step, were tested against the GRI-Mech3.0 by comparing key species, such as NOx, CO2 and CO, and gas temperature predictions in idealized reactors codes under mild combustion conditions. It is thus concluded that the 9-step mechanism appears to be a promising reduced mechanism that can be used in multi-dimensional codes for modeling mild combustion of natural gas.
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Bresnick, Emery H., Hogune Im, Kirby D. Johnson e Jeffrey A. Grass. "Dissecting a Multi-Step Mechanism of Beta-Globin Transcriptional Activation." Blood 104, n. 11 (16 novembre 2004): 1207. http://dx.doi.org/10.1182/blood.v104.11.1207.1207.

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Abstract Defining factors and signals that establish and maintain the native nucleoprotein structure of endogenous chromatin domains represents a powerful approach for elucidating transcriptional mechanisms. In adult erythroid cells, the locus control region (LCR) and the adult beta-globin genes of the murine beta-globin locus are highly enriched in acetylated histones H3 and H4 (acH3, acH4) and H3 methylated at lysine 4 (H3-meK4). By contrast, the embryonic beta-globin genes reside in a broad region of reduced acetylation. Histone H3 methylated at lysine 79 (H3-meK79) is highly enriched at the adult beta-globin genes, but not at the LCR. To elucidate the molecular steps in beta-globin transcriptional activation, genetic complementation experiments were conducted in GATA-1-null G1E cells containing an estrogen receptor hormone binding domain-GATA-1 fusion protein (ER-GATA-1). Kinetic analysis of ER-GATA-1 occupancy of chromatin and establishment of the histone modification pattern by chromatin immunoprecipitation (ChIP) revealed that GATA-1 occupies multiple regions within the LCR prior to the beta-major promoter. Chromatin accessibility at the promoter was low until ER-GATA-1 assembled into regulatory complexes at the LCR. Subsequently, ER-GATA-1 accessed the beta-major promoter, induced acH3, RNA polymerase II (Pol II) recruitment, and elevated H3-meK79. Acquisition of transcriptional competence appears to require establishment of H3-meK4, which is GATA-1-independent. Blocking transcriptional elongation did not erase H3-meK79, indicating that maintenance of H3-meK79 does not require ongoing elongation. Analysis of N-terminal GATA-1 deletion mutants that retain Friend of GATA-1 (FOG-1) binding and DNA binding activities revealed that FOG-1 binding and DNA binding activities are insufficient for Pol II recruitment and chromatin modification at the promoter. These results support a model in which ER-GATA-1 binding to the LCR increases acH3 at the promoter as an early event in transcriptional activation, which is tightly coupled to ER-GATA-1 access to the promoter, increased promoter accessibility, and Pol II recruitment. Increased promoter accessibility, which likely permits ER-GATA-1 access to the promoter, precedes maximal induction of H3-meK79, a late event in activation. Given the dynamic regulation of H3-meK79 by GATA-1 and NF-E2 and the modulation of H3-meK79 levels during erythropoiesis, we propose that H3-meK79 is a crucial signal that controls the rate of beta-globin transcription. Studies are underway to test this hypothesis and to dissect mechanisms underlying the requirement of N-terminal sequences of GATA-1 for Pol II recruitment and chromatin modification. Furthermore, having identified individual steps in transcriptional activation of the endogenous beta-globin genes, we are testing whether inducers of human fetal hemoglobin affect these specific steps. GATA-1 has been reported by the Crispino group to be expressed as an N-terminally truncated species in megakaryoblastic leukemia. Defining how the N-terminus functions should therefore lead to a molecular understanding of this disorder. As the N-termini of GATA factors differ considerably, one might expect these divergent sequences to establish GATA factor-specific functions, and this prediction is being tested via detailed analysis of the activities of chimeric GATA factors.
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Sun, Yihao, Qin Tan, Chao Yan, Yuan Chang, Xiaojia Xiang e Han Zhou. "Multi-UAV Coverage through Two-Step Auction in Dynamic Environments". Drones 6, n. 6 (20 giugno 2022): 153. http://dx.doi.org/10.3390/drones6060153.

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The cooperation of multiple unmanned aerial vehicles (Multi-UAV) can effectively solve the area coverage problem. However, developing an online multi-UAV coverage approach remains a challenge due to energy constraints and environmental dynamics. In this paper, we design a comprehensive framework for area coverage with multiple energy-limited UAVs in dynamic environments, which we call MCTA (Multi-UAV Coverage through Two-step Auction). Specifically, the online two-step auction mechanism is proposed to select the optimal action. Then, an obstacle avoidance mechanism is designed by defining several heuristic rules. After that, considering energy constraints, we develop the reverse auction mechanism to balance workload between multiple UAVs. Comprehensive experiments demonstrate that MCTA can achieve a high coverage rate while ensuring a low repeated coverage rate and average step deviation in most circumstances.
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Li, Xianghui, Wei Zheng e Yang Li. "An axiomatic and non-cooperative approach to the multi-step Shapley value". RAIRO - Operations Research 55, n. 3 (maggio 2021): 1541–57. http://dx.doi.org/10.1051/ro/2021073.

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Inspired by the two-step Shapley value, in this paper we introduce and axiomatize the multi-step Shapley value for cooperative games with levels structures. Moreover, we design a multi-step bidding mechanism, which implements the value strategically in subgame perfect Nash equilibrium for superadditve games.
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Tesi sul tema "Multi-step mechanism"

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Lin, Yuan. "Modeling of dielectrophoresis in micro and nano systems". Doctoral thesis, Stockholm : Mekanik, Mechanics, Kungliga Tekniska högskolan, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4784.

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Dinh, Duy Cuong. "Development of a Detailed Approach to Model the Solid Pyrolysis with the Coupling Between Solid and Gases Intra-Pores Phenomena". Electronic Thesis or Diss., Chasseneuil-du-Poitou, Ecole nationale supérieure de mécanique et d'aérotechnique, 2024. http://www.theses.fr/2024ESMA0029.

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La pyrolyse du bois est un processus crucial dans la science de la sécurité incendie car elle affecte la décomposition thermique et le comportement de combustion des matériaux. Le bois est un composite biopolymères (cellulose, hémicellulose et lignine) qui subit une pyrolyse complexe, produisant du charbon solide, du goudron et des gaz. Le processus de pyrolyse modifie également certaines caractéristiques importantes de l’échantillon (densité, conductivité thermique, capacité thermique, porosité, perméabilité, émissivité...) qui évoluent tout au long de la réaction de décomposition. La compréhension de ces transformations est cruciale pour la modélisation du comportement du feu des solides. Les évolutions des masses normalisées finales entre les expériences ATG et en cône calorimètre remettent en cause les modèles de taux de réaction solides existants. Les modèles actuels supposent souvent un ordre de réaction égal à 1, ce qui conduit à des inexactitudes lorsque l’ordre de réaction diffère de 1. Pour surmonter ces lacunes, un nouveau modèle basé sur la conversion, appelé ”Masse Initiale Virtuelle”, est proposé. Ce modèle est basé sur des données issues d’essais ATG. Il calcule la vitesse de chaque réaction dans le cas de mécanismes de pyrolyse complexes, avec de nombreuses réactions séquentielles et compétitives et a été implémenté en C++. Le code C++ de ce modèle est intégré avec l’outil DAKOTA pour permettre l’optimisation multi-objectif par algorithme génétique (MOGA) des paramètres cinétiques sur plusieurs vitesses de chauffage. Ce modèle de « Masse Initiale Virtuelle » est intégré dans la boîte à outils d’analyse des matériaux poreux basée sur OpenFOAM (PATO), un outil Open Source créé par la NASA. D’autres modèles de transferts de masse, de chaleur et de conservation des espèces en plus des propriétés des matériaux sont créés dans ce nouveau cadre. Un modèle informatique pour les réactions secondaires (réactions en phase gazeuse qui produisent du charbon secondaire) est implémenté dans PATO. Les simulations des essais en cône calorimètre sont effectuées dans des modèles 1D et 2D axisymétriques pour explorer l’influence des propriétés anisotropes du bois, en particulier l’orientation de ses fibres. La comparaison des modèles avec et sans réactions secondaires démontre le rôle de ces dernières dans la distribution de la chaleur et la production de charbon secondaire. Ce résultat explique la différence de masse finale observée expérimentalement entre les tests en ATG et en cône calorimètre. La comparaison des résultats expérimentaux et numériques montre la pertinence de cette approche pour simuler le comportement complexe de la pyrolyse du bois en mettant en évidence l’importance des voies de réaction, des réactions secondaires, du transfert de chaleur, du transfert de masse et des phénomènes d’interaction intra-pore
Pyrolysis of wood is a crucial process in fire safety science because it affects the thermal decomposition and combustion behavior of materials. Wood, a composite of biopolymeric components (cellulose, hemicellulose and lignin) undergoes complex pyrolysis to yield solid char, tar and gases as it thermally decomposes. The pyrolysis process also changes some important characteristics of the sample (density, thermal conductivity, heat capacity, porosity, permeability, emissivity...) that evolve throughout the reaction. Understanding these transformations is crucial for the correct modeling of fire behavior and material response under different thermal conditions. Different final normalized mass between TGA and cone calorimeter experiments challenge existing solid reaction rate models, according to experimental studies. Current models often assume a reaction order of 1, which oversimplifies the complexity of wood pyrolysis and leads to inaccuracies when the reaction order differs from 1. To overcome these shortcomings, a brand new conversion-based model, called ”Virtual Initial Mass”, is proposed. This model, based on TGA data, calculates the reaction rate for each reaction in complicated pyrolysis mechanisms. It supports mechanisms with numerous sequential and competitive reactions and has been implemented in C++. The C++ code for this model is integrated with the DAKOTA toolkit to perform multi objective genetic algorithm (MOGA) optimization of kinetic parameters for multiple heating rates. This ”Virtual Initial Mass” model is integrated in the Porous material Analysis Toolbox based on OpenFOAM (PATO) an Open Source tool distributed by NASA. Further mass transfer, heat transfer, species conservation models in addition to material properties are created within this new framework. A computational model for secondary reactions (gas-phase reactions that produce secondary char) is implemented in PATO. These secondary reactions solidify the sample and distribute heat back into the system. Simulations of cone calorimeter tests are performed in 1D and 2D axisymmetric models to explore the influence of anisotropic wood properties, particularly the orientation of wood fibers. Comparison of models with and without secondary reactions demonstrates their role in heat distribution and secondary char production and points out the experimentally observed difference in normalized mass between TGA and cone calorimeter tests. The model is verified by comparison with experimental results to show that it can simulate the complicated behavior of wood pyrolysis as well as emphasizes the importance of reaction pathways, secondary reactions, heat transfer, mass transfer and intra-pore interaction phenomena
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Prakash, Arun. "Multi-time-step domain decomposition and coupling methods for non-linear structural dynamics /". 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3290351.

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Thesis (Ph. D.)--University of Illinois at Urbana-Champaign, 2007.
Source: Dissertation Abstracts International, Volume: 68-11, Section: B, page: 7516. Adviser: Keith D. Hjelmstad. Includes bibliographical references (leaves 174-182). Available on microfilm from Pro Quest Information and Learning.
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(11192533), Kaleb M. Byers. "Platforms and Molecular Mechanisms for Improving Signal Transduction and Signal Enhancement in Multi-step Point-Of-Care Diagnostics". Thesis, 2021.

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Swift recognition of disease-causing pathogens at the point-of-care enables life-saving treatment and infection control. However, current rapid diagnostic devices often fail to detect the low concentrations of pathogens present in the early stages of infection, causing delayed and even incorrect treatments. Rapid diagnostics that require multiple steps and/or elevated temperatures to perform have a number of barriers to use at the point-of-care and in the field, and despite efforts to simplify these platforms for ease of use, many still require diagnostic-specific training for the healthcare professionals who use them. Most nucleic acid amplification assays require hours to perform in a sterile laboratory setting that may be still more hours from a patient’s bedside or not at all feasible for transport in remote or low-resourced areas. The cold-chain storage of reagents, multistep sample preparation, and costly instrumentation required to analyze samples has prohibited many nucleic acid detection and antibody-based assays from reaching the point-of-care. There remains a critical need to bring rapid and accessible pathogen identification technologies that determine disease status and ensure effective treatment out of the laboratory.

Paper-based diagnostics have emerged as a portable platform for antigen and nucleic acid detection of pathogens but are often limited by their imperfect control of reagent incubation, multiple complex steps, and inconsistent false positive results. Here, I have developed mechanisms to economically improve thermal incubations, automate dried reagent flow for multistep assays, and specifically detect pathogenic antigens while improving final output sensitivity on paper-based devices. First, I characterize miniaturized inkjet printed joule-heaters (microheaters) that enable thermal control for pathogen lysis and nucleic acid amplification incubation on a low-cost paper-based device. Next, I explore 2-Dimensional Paper Networks as a means to automate multistep visual enhancement reactions with dried reagents to increase the sensitivity and readability of nucleic acid detection with paper-based devices. Lastly, I aim to create a novel Reverse-Transcription Recombinase Polymerase Reaction mechanism to amplify and detect a specific region of the Spike protein domain of SARS-CoV-2. This will allow the rapid detection of SARS-CoV-2 infections to aid in managing the current COVID-19 pandemic. In the future, these tools could be integrated into a rapid diagnostic test for SARS-CoV-2 and other pathogens, ultimately improving the accessibility and sensitivity of rapid diagnostics on multiple fronts.

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Ghosh, Susanta. "Improved Numerical And Numeric-Analytic Schemes In Nonlinear Dynamics And Systems With Finite Rotations". Thesis, 2008. https://etd.iisc.ac.in/handle/2005/682.

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This thesis deals with different computational techniques related to some classes of nonlinear response regimes of engineering interest. The work is mainly divided into two parts. In the first part different numeric-analytic integration techniques for nonlinear oscillators are developed. In the second part, procedures for handling arbitrarily large rotations are addressed and a few novel developments are reported in the process. To begin the first part, we have proposed an explicit numeric-analytic technique, based on the Adomian decomposition method, for integrating strongly nonlinear oscillators. Numerical experiments suggest that this method, like most other numerical techniques, is versatile and can accurately solve strongly nonlinear and chaotic systems with relatively larger step-sizes. It is then demonstrated that the procedure may also be effectively employed for solving two-point boundary value problems with the help of a shooting algorithm. This has been followed up with the derivation and numerical exploration of variants of a recently developed numeric-analytic technique, the multi-step transversal linearization (MTrL), in the context of nonlinear oscillators of relevance in engineering dynamics. A considerable generalization and improvement over the original form of a MTrL strategy is achieved in this study. Finally, we have used the concept of MTrL method on the nonlinear variational (rate) equation corresponding to a nonlinear oscillator and thus derive another family of numeric-analytic techniques, presently referred to as the multi-step tangential linearization (MTnL). A comparison of relative errors through the MTrL and MTnL techniques consistently indicate a superior quality of approximation via the MTrL route. In the second part of the thesis, a scheme for numerical integration of rigid body rotation is proposed using only rudimentary tensor analysis. The equations of motion are rewritten in terms of rotation vectors lying in same tangent spaces, thereby facilitating vector space operations consistent with the underlying geometric structure of rotation. One of the most important findings of this part of the dissertation is that the existing constant-preserving algorithms are not necessarily accurate enough and may not be ideally applicable to cases wherein numerical accuracy is of primary importance. In contrast, the proposed rotation-algorithms, the higher order ones in particular, are significantly more accurate for conservative rotational systems for reasonably long time. Similar accuracy is expected for dissipative rotational systems as well. The operators relating rotation variables corresponding to different tangent spaces are also investigated and this should provide further insight into the understanding of rotation vector parametrization. A rotation update is next proposed in terms of rotation vectors. This update, employed along with interpolation of relative rotations, gives a strain-objective and path independent finite element implementation of a geometrically exact beam. The method has the computational advantage of requiring considerably less nodal variables due to the use of rotation vector parametrization. We have proposed a new isoparametric interpolation of nodal quaternions for computing the rotation field within an element. This should be a computationally efficient alternative to the interpolation of local rotations. It has been proved that the proposed interpolation of rotation leads to the objectivity of strain measures. Several numerical experiments are conducted to demonstrate the frame invariance, path-independence and other superior aspects of the present approach vis-`a-vis the existing methods based on the rotation vector parametrization. It is emphasized that, in order to develop an objective finite element formulation, the use of relative rotation is not mandatory and an interpolation of total rotation variables conforming with the rotation manifold should suffice.
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Ghosh, Susanta. "Improved Numerical And Numeric-Analytic Schemes In Nonlinear Dynamics And Systems With Finite Rotations". Thesis, 2008. http://hdl.handle.net/2005/682.

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This thesis deals with different computational techniques related to some classes of nonlinear response regimes of engineering interest. The work is mainly divided into two parts. In the first part different numeric-analytic integration techniques for nonlinear oscillators are developed. In the second part, procedures for handling arbitrarily large rotations are addressed and a few novel developments are reported in the process. To begin the first part, we have proposed an explicit numeric-analytic technique, based on the Adomian decomposition method, for integrating strongly nonlinear oscillators. Numerical experiments suggest that this method, like most other numerical techniques, is versatile and can accurately solve strongly nonlinear and chaotic systems with relatively larger step-sizes. It is then demonstrated that the procedure may also be effectively employed for solving two-point boundary value problems with the help of a shooting algorithm. This has been followed up with the derivation and numerical exploration of variants of a recently developed numeric-analytic technique, the multi-step transversal linearization (MTrL), in the context of nonlinear oscillators of relevance in engineering dynamics. A considerable generalization and improvement over the original form of a MTrL strategy is achieved in this study. Finally, we have used the concept of MTrL method on the nonlinear variational (rate) equation corresponding to a nonlinear oscillator and thus derive another family of numeric-analytic techniques, presently referred to as the multi-step tangential linearization (MTnL). A comparison of relative errors through the MTrL and MTnL techniques consistently indicate a superior quality of approximation via the MTrL route. In the second part of the thesis, a scheme for numerical integration of rigid body rotation is proposed using only rudimentary tensor analysis. The equations of motion are rewritten in terms of rotation vectors lying in same tangent spaces, thereby facilitating vector space operations consistent with the underlying geometric structure of rotation. One of the most important findings of this part of the dissertation is that the existing constant-preserving algorithms are not necessarily accurate enough and may not be ideally applicable to cases wherein numerical accuracy is of primary importance. In contrast, the proposed rotation-algorithms, the higher order ones in particular, are significantly more accurate for conservative rotational systems for reasonably long time. Similar accuracy is expected for dissipative rotational systems as well. The operators relating rotation variables corresponding to different tangent spaces are also investigated and this should provide further insight into the understanding of rotation vector parametrization. A rotation update is next proposed in terms of rotation vectors. This update, employed along with interpolation of relative rotations, gives a strain-objective and path independent finite element implementation of a geometrically exact beam. The method has the computational advantage of requiring considerably less nodal variables due to the use of rotation vector parametrization. We have proposed a new isoparametric interpolation of nodal quaternions for computing the rotation field within an element. This should be a computationally efficient alternative to the interpolation of local rotations. It has been proved that the proposed interpolation of rotation leads to the objectivity of strain measures. Several numerical experiments are conducted to demonstrate the frame invariance, path-independence and other superior aspects of the present approach vis-`a-vis the existing methods based on the rotation vector parametrization. It is emphasized that, in order to develop an objective finite element formulation, the use of relative rotation is not mandatory and an interpolation of total rotation variables conforming with the rotation manifold should suffice.
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Μαραζιώτη, Παναγιώτα. "Ανάπτυξη πειραματικής και υπολογιστικής μεθόδου για την μελέτη αεροθερμοδυναμικού πεδίου και του εκπεμπόμενου θορύβου και ρυπών από συρρέουσες και ανακυκλοφορούσες τυρβώδεις φλόγες προπανίου". Thesis, 2006. http://nemertes.lis.upatras.gr/jspui/handle/10889/1439.

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Η παρούσα διατριβή μελετά τις δυνατότητες υπολογισμού του πεδίου ροής δύο λειτουργικών παραμέτρων συμπεριλαμβανομένων του εκπεμπόμενου θορύβου και των εκπεμπόμενων ρύπων. Εξετάζεται η αλληλεπίδραση της καύσης με το ρευστο-θερμοδυναμικό πεδίο και τις χημικές αντιδράσεις. Περιγράφονται συνοπτικά οι διέπουσες εξισώσεις, οι μέθοδοι και τα μοντέλα της τυρβώδους καύσης και επισημαίνονται τα πλεονεκτήματα του μοντέλου των μεγάλων δινών (LES) το οποίο επιλέχθηκε εδώ. Αναπτύσσεται ένας εύχρηστος, από την ρευστοδυναμική υπολογιστική μεθοδολογία, πολυβηματικός μηχανισμός για δύο καύσιμα άμεσου ενδιαφέροντος το μεθάνιο και το προπάνιο. Προτείνεται, δηλαδή, ένα απλοποιημένο χημικό σχήμα για την οξείδωση των βασικών καυσίμων το οποίο περιέχει τον σχηματισμό του NΟx και της παραγωγής καπναιθάλης. Μετά από ανάλυση του ρόλου της καύσης στην ακουστική διακρίνονται οι δύο χαρακτηριστικοί τύποι: του θορύβου τυρβώδους καύσης (βόμβος – roar) και του θορύβου από τις ταλαντώσεις της καύσης (combustion oscillation). Παρουσιάζεται η κυματική εξίσωση και εισάγεται η έννοια του θερμο-ακουστικού όρου ο οποίος είναι συνάρτηση της απελευθερωμένης θερμότητας (q) στην φλόγα και εμφανίζεται ως όρος πηγής στην βασική εξίσωση. Στη συνέχεια η φλόγα εξετάζεται ως αυτόνομος πηγή αλλά και ως ενισχυτής θορύβου. Με την προσέγγιση της Προσομοίωσης των Μεγάλων Δινών (Large Eddy Simulation, LES) αναπτύχθηκε μια μεθοδολογία υπολογισμού του θορύβου που εκπέμπεται από το μέτωπο τυρβωδών φλογών διάχυσης. Στο πλαίσιο της προτεινομένης μεθοδολογίας το αποτέλεσμα ήταν η ανάπτυξη ενός τρισδιάστατου προγνωστικού υπολογιστικού κώδικα. Στην συνέχεια υπολογίζεται το αεροθερμοδυναμικό τυρβώδες πεδίο ροής μέσω τελειοποίησης κωδίκων του Εργαστηρίου Τεχνικής Θερμοδυναμικής, των κωδίκων που αναπτύχθηκαν στο πλαίσιο της παρούσης εργασίας αλλά και του εμπορικού κώδικα Fluent. Η μεθοδολογία, που αναπτύχθηκε με την παρούσα ερευνητική εργασία, πιστοποιήθηκε μέσω μιας σειράς πρωτότυπων μετρήσεων, του εκπεμπόμενου θορύβου στις συρρέουσες, εφαπτόμενες και ανυψωμένες και ανακυκλοφορούσες (χαμηλού και υψηλού λόγου καυσίμου/αέρα) φλόγες, σε πρωτότυπες πειραματικές διατάξεις του Εργαστηρίου. Συγκεκριμένα διαμορφώθηκε ένας καινοτόμος αεροδυναμικός φλογοσυγκρατητής πολλαπλών εγχύσεων που διατηρεί μια πλούσια γκάμα φλογών με ιδιαίτερα χαμηλό λόγο καυσίμου/αέρα. Επιτεύχθηκαν πειραματικές μετρήσεις, του ορμικού και θερμοκρασιακού πεδίου διαφόρων μορφών τυρβωδών φλογών, συντάχθηκαν σχετικά διαγράμματα και υπολογίσθηκαν οι αρχικές και οριακές συνθήκες των πειραμάτων.
In the present work the calculation of two parameters, the radiated noise and pollutants are studied. The interaction between combustion, the aerothermodynamical field and the chemical reactions is studied. The equations, the methods and the models of turbulent combustion are described here and the advantages of the large eddy simulation model (LES) which has been chosen for this case, are marked. A multi-step chemistry mechanism is developed for two fuels of great interest: methane and propane. A simple chemical scheme for the oxidation of basic fuels which includes the formation of NOx and soot is suggested in the present work. After analyzing the role of combustion in the acoustics two types of noise are distinguished the turbulent combustion noise and the noise from combustion oscillation. The wave equation is presented and the definition of thermo acoustic term which is a function of the heat release q in flame and it appears as a source term in the basic equation. The flame is examined as an autonomous source as well as a noise amplifier. With the approach of large eddy simulation (LES) a methodology for the noise calculation is developed which noise is from the turbulent diffusion flame front. In the place of the suggested methodology the result was the development of a 3-D computational code. The turbulent aerothermodynamical flow field is computed by codes has been developed in the laboratory of technical thermodynamic and by the commercial code (fluent). The methodology, which has been developed in the present work, has been certificated through a series of original measurements of the emitted noise in coaxial, tangential and lifted flames in original experimentallayouts.
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Capitoli di libri sul tema "Multi-step mechanism"

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Xiang, Yaoci, Chong Zhao, Xing Wei, Yang Lu e Shaofan Liu. "Multi-step Domain Adaption Image Classification Network via Attention Mechanism and Multi-level Feature Alignment". In Wireless Algorithms, Systems, and Applications, 11–19. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-86137-7_2.

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Wang, Zheng, Xinyu Qu, Yang Yin e Houpu Li. "Research on Dynamic Path Planning Algorithm for Unmanned Underwater Vehicles Based on Multi-step Mechanism DDQN". In Communications in Computer and Information Science, 409–17. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-2275-4_32.

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Butcher, Eugene C. "Leukocyte-Endothelial Cell Adhesion as an Active, Multi-Step Process: A Combinatorial Mechanism for Specificity and Diversity in Leukocyte Targeting". In Advances in Experimental Medicine and Biology, 181–94. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3396-2_23.

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Calcagno, Anna Maria, e Suresh V. Ambudkar. "Molecular Mechanisms of Drug Resistance in Single-Step and Multi-Step Drug-Selected Cancer Cells". In Methods in Molecular Biology, 77–93. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-416-6_5.

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Lee, Jae Jong, Seung Woo Lee, Hyun Taek Cho, Gee Hong Kim e Kee Bong Choi. "Single-Step UV Nanoimprinting Lithography with Multi-Head Imprinting System and Its Applications". In Experimental Mechanics in Nano and Biotechnology, 441–44. Stafa: Trans Tech Publications Ltd., 2006. http://dx.doi.org/10.4028/0-87849-415-4.441.

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Winter, Maximilian, e Christian Breitsamter. "Coupling of Recurrent and Static Neural Network Approaches for Improved Multi-step Ahead Time Series Prediction". In Notes on Numerical Fluid Mechanics and Multidisciplinary Design, 433–42. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64519-3_39.

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Furuichi, N., T. Hachiga, K. Hishida e M. Kumada. "A Flow Structure at Reattachment Region of a Two-Dimensional Backward-Facing Step by Using Advanced Multi-Point LDV". In Laser Techniques Applied to Fluid Mechanics, 143–56. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-56963-0_10.

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Potyka, Johanna, Johannes Kromer, Muyuan Liu, Kathrin Schulte e Dieter Bothe. "Modelling and Numerical Simulation of Binary Droplet Collisions Under Extreme Conditions". In Fluid Mechanics and Its Applications, 127–47. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-09008-0_7.

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AbstractThe complexity of binary droplet collisions strongly increases in case of immiscible liquids with the occurrence of triple lines or for high energetic collisions, where strong rim instabilities lead to the spattering of satellite droplets. To cope with such cases, the Volume of Fluid method is extended by an efficient interface reconstruction, also applicable to multi-material cells of arbitrary configuration, as well as an enhanced continuous surface stress model for accurate surface force computations, also applicable to thin films. For collisions of fully wetting liquids, excellent agreement to experimental data is achieved in different collision regimes. High-resolution simulations predict droplet collisions in the spattering regime and provide detailed insights into the evolution of the rim instability. Another challenge is the numerical prediction of the collision outcome in the bouncing or coalescence region, where the rarefied gas dynamics in the thin gas film determines the collision result. To this end, an important step forward became possible by modelling the pressure in the gas film. With the introduction of an interior collision plane within the flow domain, it is now possible to simulate droplet collisions with gas film thickness reaching the physically relevant length scale.
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Atkins, Peter, George Ratcliffe, Mark Wormald e Julio de Paula. "The rate laws of multi-step reactions". In Physical Chemistry for the Life Sciences. Oxford University Press, 2023. http://dx.doi.org/10.1093/hesc/9780198830108.003.0031.

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This chapter explores the consequences of an overall reaction taking place through a sequence of elementary steps, each with a characteristic rate law. The overall rate laws are in general too difficult to solve other than by numerical methods, but two simplifications, the ‘steady-state approximation’ and the existence of a ‘pre-equilibrium’, enable the general features of networks of reactions to be established. The steady-state approximation assumes that after the intermediates have started to form, and during the major part of the reaction, their concentrations remain nearly constant and close to zero. In a pre-equilibrium the reactants and products of an early step of a reaction mechanism are supposed to have reached equilibrium. The chapter also presents a case study on the kinetics of protein unfolding.
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Bindslev, Niels. "Multi-step reaction schemes. Extending the two-step mechanism of del Castillo and Katz". In Drug-Acceptor Interactions, 139–64. Co-Action Publishing, 2008. http://dx.doi.org/10.3402/bindslev.2008.9.

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Atti di convegni sul tema "Multi-step mechanism"

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Yi, Yawen, Zhewei Huang, Mingyang Bao, Xiaodan Li e Suhua Lou. "Multi-step Short-term Load Forecasting Based on Attention Mechanism, TCN-BiLSTM Network and Decomposition-based Error Correction". In 2024 7th Asia Conference on Energy and Electrical Engineering (ACEEE), 224–31. IEEE, 2024. http://dx.doi.org/10.1109/aceee62329.2024.10651918.

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Zhang, Yu, Zhiheng Zhao, Jingyu Zhou, Zhefan Zhang e Hairui Zhou. "State of Charge Prediction Algorithm of Lithium Battery Based on Multi-Step Time Window and Time Attention Mechanism of Long Short Term Memory Network". In 2024 4th International Conference on Energy Engineering and Power Systems (EEPS), 866–70. IEEE, 2024. https://doi.org/10.1109/eeps63402.2024.10804470.

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Li, Mingxin, Shanzhi Chen e Dongliang Xie. "A multi-step vertical handoff mechanism for cellular multi-hop networks". In the 2nd ACM workshop. New York, New York, USA: ACM Press, 2007. http://dx.doi.org/10.1145/1298275.1298301.

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Ye, Dong, Junqiang Xu e Zengliang Liu. "Research on multi-step synchronous advancing mechanism of training simulation system". In 2012 International Conference on Computer Science and Information Processing (CSIP). IEEE, 2012. http://dx.doi.org/10.1109/csip.2012.6309098.

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Ren, Bixing, Yongyong Jia, Dajiang Wang, Qiang Li e Yingjie Hu. "Multi-step wind power prediction scheme based on Patch attention mechanism". In 2024 7th International Conference on Energy, Electrical and Power Engineering (CEEPE). IEEE, 2024. http://dx.doi.org/10.1109/ceepe62022.2024.10586577.

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Zhou, Yirong, Hao Chen, Jun Li, Ye Wu, Jiangjiang Wu e Luo Chen. "ST-Attn: Spatial-Temporal Attention Mechanism for Multi-step Citywide Crowd Flow Prediction". In 2019 International Conference on Data Mining Workshops (ICDMW). IEEE, 2019. http://dx.doi.org/10.1109/icdmw.2019.00092.

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Liu, Tiecheng, Baobin Zhao e Aidong Zhan. "Load Restoration Multi-Objective Optimization Strategy Based on Time Step Dynamic Contraction Mechanism". In 2022 4th International Conference on Power and Energy Technology (ICPET). IEEE, 2022. http://dx.doi.org/10.1109/icpet55165.2022.9918249.

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Jin, Yong, Kenji Fujikawa, Hiroaki Harai e Masataka Ohta. "Design and Implementation of Secure Prefetch Mechanism for Multi-step Name Resolution in DNS". In 2016 IEEE 40th Annual Computer Software and Applications Conference (COMPSAC). IEEE, 2016. http://dx.doi.org/10.1109/compsac.2016.10.

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Shang-Jeng Tsai, Tsung-Ying Sun e Shih-Hsiang Ting. "Intelligent automatic manoeuvring mechanism for computer generated forces using predictive multi-step fuzzy inference system". In 2007 IEEE International Conference on Systems, Man and Cybernetics. IEEE, 2007. http://dx.doi.org/10.1109/icsmc.2007.4413911.

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Xie, Hui, e PengYu Liang. "Improved TF-LSTM Multi-Step Vehicle Speed Prediction Model Based on LSTM and Attention Mechanism". In 2023 3rd International Conference on Robotics, Automation and Intelligent Control (ICRAIC). IEEE, 2023. http://dx.doi.org/10.1109/icraic61978.2023.00082.

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Rapporti di organizzazioni sul tema "Multi-step mechanism"

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Frey, Scott H. Cortical Mechanisms of Multi-step Action Planning. Fort Belvoir, VA: Defense Technical Information Center, dicembre 2010. http://dx.doi.org/10.21236/ada545175.

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Philosoph-Hadas, Sonia, Peter B. Kaufman, Shimon Meir e Abraham H. Halevy. Inhibition of the Gravitropic Shoot Bending in Stored Cut Flowers Through Control of Their Graviperception: Involvement of the Cytoskeleton and Cytosolic Calcium. United States Department of Agriculture, dicembre 2005. http://dx.doi.org/10.32747/2005.7586533.bard.

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Original objectives: The basic goal of the present project was to study the mechanism involved in shoot graviperception and early transduction, in order to determine the sequence of events operating in this process. This will enable to control the entire process of gravity-induced differential growth without affecting vertical growth processes essential for development. Thus, several new postulated interactions, operating at the perception and early transduction stages of the signaling cascade leading to auxin-mediated bending, were proposed to be examined in snapdragon spikes and oat shoot pulvini, according to the following research goals: 1) Establish the role of amyloplasts as gravireceptors in shoots; 2) Investigate gravity-induced changes in the integrity of shoot actin cytoskeleton (CK); 3) Study the cellular interactions among actin CK, statoliths and cell membranes (endoplasmic reticulum - ER, plasma membrane - PM) during shoot graviperception; 4) Examine mediation of graviperception by modulations of cytosolic calcium - [Ca2+]cyt, and other second messengers (protein phosphorylation, inositol 1,4,5-trisphosphate - IP3). Revisions: 1) Model system: in addition to snapdragon (Antirrhinum majus L.) spikes and oat (Avena sativa) shoot pulvini, the model system of maize (Zea mays) primary roots was targeted to confirm a more general mechanism for graviperception. 2) Research topic: brassinolide, which were not included in the original plan, were examined for their regulatory role in gravity perception and signal transduction in roots, in relation to auxin and ethylene. Background to the topic: The negative gravitropic response of shoots is a complex multi-step process that requires the participation of various cellular components acting in succession or in parallel. Most of the long-lasting studies regarding the link between graviperception and cellular components were focused mainly on roots, and there are relatively few reports on shoot graviperception. Our previous project has successfully characterized several key events occurring during shoot bending of cut flowers and oat pulvini, including amyloplast displacement, hormonal interactions and differential growth analysis. Based on this evidence, the present project has focused on studying the initial graviperception process in flowering stems and cereal shoots. Major conclusions and achievements: 1) The actin and not the microtubule (MT) CK is involved in the graviperception of snapdragon shoots. 2) Gravisensing, exhibited by amyloplast displacement, and early transduction events (auxin redistribution) in the gravitropic response of snapdragon spikes are mediated by the acto-myosin complex. 3) MTs are involved in stem directional growth, which occurs during gravitropism of cut snapdragon spikes, but they are not necessary for the gravity-induced differential growth. 4) The role of amyloplasts as gravisensors in the shoot endodermis was demonstrated for both plant systems. 5) A gravity-induced increase in IP.
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Hertel, Thomas, e Jeff Reimer. Estimating the Poverty Impacts of Trade Liberalization. GTAP Working Paper, gennaio 2003. http://dx.doi.org/10.21642/gtap.wp20.

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As a new round of World Trade Organization negotiations is being launched with greater emphasis on developing country participation, a body of literature is emerging which quantifies how international trade affects the poor in developing countries. This survey summarizes and classifies thirty-five studies from this literature into four methodological categories: cross-country regression, partial-equilibrium/cost-of-living analysis, general-equilibrium simulation, and micro-macro synthesis. These categories encompass a broad range of methodologies in current use. The continuum of approaches is bounded on one end by econometric analysis of household expenditure data, which is the traditional domain of poverty specialists, and sometimes labeled the “bottom-up” approach. On the other end of the continuum are computable general equilibrium models based on national accounts data, or what might be called the “top-down” approach. Another feature of several recent trade/poverty studies – and one of the primary conclusions to emerge from the October 2000 Conference on Poverty and the International Economy sponsored by Globkom and the World Bank – is recognition that factor markets are perhaps the most important linkage between trade and poverty, since households tend to be much more specialized in income than they are in consumption. Meanwhile, survey data on the income sources of developing-country households has become increasingly available. As a result, this survey gives particular emphasis to the means by which studies address factor market linkages between trade and poverty. The general conclusion is that any analysis of trade and poverty needs to be informed by both the bottom-up and top-down perspectives. Indeed, recent “two-step” micro-macro studies sequentially link these two types of frameworks, such that general equilibrium mechanisms are incorporated along with detailed household survey information. Another methodology similar in spirit and also increasingly used involves the incorporation of large numbers of surveyed households into a general-equilibrium simulation model. Although most of these studies have so far been limited to a single region, these approaches can be readily adapted for multi-region modeling so that trade-poverty comparisons can be made across countries within a consistent framework.
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