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Letteratura scientifica selezionata sul tema "Mtspo"

Autore: Grafiati

Pubblicato: 2 novembre 2024

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Articoli di riviste sul tema "Mtspo"

Jaremko, Mariusz, Łukasz Jaremko, Garima Jaipuria, Stefan Becker e Markus Zweckstetter. "Structure of the mammalian TSPO/PBR protein". Biochemical Society Transactions 43, n. 4 (1 agosto 2015): 566–71. http://dx.doi.org/10.1042/bst20150029.

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The 3D structure of the 18-kDa transmembrane (TM) protein TSPO (translocator protein)/PBR (peripheral benzodiazepine receptor), which contains a binding site for benzodiazepines, is important to better understand its function and regulation by endogenous and synthetic ligands. We have recently determined the structure of mammalian TSPO/PBR in complex with the diagnostic ligand PK11195 [1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide; Jaremko et al. (2014) Science 343, 1363–1366], providing for the first time atomic-level insight into the conformation of this protein, which is up-regulated in various pathological conditions including Alzheimer's disease and Parkinson's disease. Here, we review the studies which have probed the structural properties of mammalian TSPO/PBR as well as the homologues bacterial tryptophan-rich sensory proteins (TspOs) over the years and provide detailed insight into the 3D structure of mouse TSPO (mTSPO)/PBR in complex with PK11195.

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Massawe, Ezrael J., Richard Kimwaga e Fredrick Mwanuzi. "Modelling Transport of Nitrogen Compounds in Geita Wetland along Mtakuja River". Tanzania Journal of Engineering and Technology 37, n. 2 (30 giugno 2018): 89–106. http://dx.doi.org/10.52339/tjet.v37i2.486.

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The impacts of excessive nitrogen loading to streams in a watershed occur in the receiving waters such as rivers at the outlet of the watershed. To quantify the impacts of land use and management practices on the nitrogen loading at the watershed outlet, simulation models are needed that can both predict the nitrogen loading at the edge of individual fields and predict the fate of nitrogen as it moves through the river network to the watershed outlet. This paper presents the results of a model analysis for describing the processes governing transformations and transport of nitrogen compounds (NO3-N and NH4-N) through Mtakuja River in the Geita wetland. The model was made in Soil and Water Assessment Tool (SWAT), a watershed model developed to assess the impact of land management practices on water, sediment and agricultural chemical yields with varying soils, land use and management conditions. Two monitoring stations namely MTSP1 and MTSP2 were established along Mtakuja River. A set of SWAT model inputs representative of the water conditions was collected from the established monitoring stations. The model was calibrated and validated for the prediction of flow and nitrogen compounds (NO3-N and NH4-N) transport, against a set of measured mean monthly monitoring data. Sensitive model parameters were adjusted within their feasible ranges during calibration to minimize model prediction errors. At the gauging station MTSP2, the calibration results showed that the model predicted mean monthly flow within 18% of the measured mean monthly flow with the r2 coefficient and Nash-Sutcliffe (NSE) were 0.84 and 0.82, respectively. At the water quality monitoring station MTSP2, the calibration results showed the model predicted nitrogen compounds (NO3-N and NH4-N) loadings within 21% and 23% of their respective measured mean monthly loadings. The mean monthly comparisons of r 2 values for nitrogen compounds ranged from 0.77 to 0.81 while the Nash-Sutcliffe Efficiency (NSE) values were between 0.72 and 0.73. The model results and field measurements demonstrated that about 70% of the annual nitrogen compounds loadings which would otherwise reach Lake Victoria are retained in the wetland. The Mtakuja river model can therefore be used for prediction of nitrogen compounds (NO3-N and NH4-N) transformation processes in the Geita wetland.

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Jin, Hui, Qingsong He, Miao He, Fangchao Hu e Shiqing Lu. "New Method of Path Optimization for Medical Logistics Robots". Journal of Robotics and Mechatronics 33, n. 4 (20 agosto 2021): 944–54. http://dx.doi.org/10.20965/jrm.2021.p0944.

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The path planning problem of logistics robots is mainly subjected to the time cost of the operation of the mathematical model. To save the time of refilling process in the fast medicine dispensing system (FMDS), the optimization procedure is divided into two steps in this study. First, a new mathematical model called the multiple steps traveling salesman problem model (MTSPM) is proposed to optimize the replenishment quantity of each picking and establish picking sets. Second, an improved ant colony optimization (IACO) algorithm is employed, considering the effects of velocity, acceleration, and deceleration in the refilling route during the development of the new model. Simulation results and operational results demonstrated that MTSPM-IACO was better than both the order picking model (OPM) and MTSPM-ACO in terms of saving refilling time. Compared to the OPM, the optimization of the refilling time of MTSPM-IACO was more than 1.73% in simulation and 15.26% in operation. Compared to MTSPM-ACO, the optimization of the refilling time of MTSPM-IACO was more than 0.13% in simulation and 1.67% in operation.

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Teplonogova, Maria A., Marina V. Volostnykh, Alexey D. Yapryntsev, Madina M. Sozarukova, Yulia G. Gorbunova, Ekaterina D. Sheichenko, Alexander E. Baranchikov e Vladimir K. Ivanov. "Switchable Nanozyme Activity of Porphyrins Intercalated in Layered Gadolinium Hydroxide". International Journal of Molecular Sciences 23, n. 23 (6 dicembre 2022): 15373. http://dx.doi.org/10.3390/ijms232315373.

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In this study, organo-inorganic nanohybrids LHGd-MTSPP with enzyme-like activity were prepared by in situ intercalation of anionic 5,10,15,20-tetrakis-(4-sulfonatophenyl)porphyrin and its complexes with Zn(II) and Pd(II) (MTSPP, M = 2H, Zn(II) and Pd(II)) into gadolinium layered hydroxide (LHGd). The combination of powder XRD, CHNS analysis, FT-IR, EDX, and TG confirmed the layered structure of the reaction products. The basal interplanar distances in LHGd-MTSPP samples were 22.3–22.6 Å, corresponding to the size of an intercalated tetrapyrrole molecule. According to SEM data, LHGd-MTSPP hybrids consisted of individual lamellar nanoparticles 20–50 nm in thickness. The enzyme-like activity of individual constituents, LHGd-Cl and sulfoporphyrins TSPP, ZnTSPP and PdTSPP, and hybrid LHGd-MTSPP materials, was studied by chemiluminescence analysis using the ABAP/luminol system in phosphate buffer solution. All the individual porphyrins exhibited dose-dependent antioxidant properties with respect to alkylperoxyl radicals at pH 7.4. The intercalation of free base TSPP porphyrin into the LHGd preserved the radical scavenging properties of the product. Conversely, in LHGd-MTSPP samples containing Zn(II) and Pd(II) complexes, the antioxidant properties of the porphyrins changed to dose-dependent prooxidant activity. Thus, an efficient approach to the design and synthesis of advanced LHGd-MTSPP materials with switchable enzyme-like activity was developed.

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Cokrowibowo, Sugiarto, Ismail e Indra. "Multiple Traveling Salesman Problem Menggunakan Algoritma Ant Colony Optimization dengan Operasi Elitism". Journal of Computer and Information System ( J-CIS ) 1, n. 2 (17 ottobre 2019): 23–28. http://dx.doi.org/10.31605/jcis.v1i2.619.

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The Multiple Traveling Salesman Problem (MTSP) is a combinatorial optimization problem and extension of Traveling Salesman Problem (TSP). There are many implementation of MTSP on transportation and scheduling. MTSP is an NP-hard problem. This paper study about solving MTSP using Ant Colony Optimization and Elitisme operator from Genetic Algorithm. The result of this combination algorithm enhance the solution search performace because of the elitism operation which ensure the solution value always increase.

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Zhang, Wenze, e Chenyang Xu. "A comparative study between SA and GA in solving MTSP". Theoretical and Natural Science 18, n. 1 (8 dicembre 2023): 61–70. http://dx.doi.org/10.54254/2753-8818/18/20230321.

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The multiple traveling salesmen problems (MTSP) is a combinatorial optimization and np-hard problem. In practice, the computational resource required to solve such problems is usually prohibitive, and, in most cases, using heuristic algorithms is the only practical option. This paper implements genetic algorithms (GA) and simulated annealing (SA) to solve the MTSP and does an experimental study based on a benchmark from the TSPLIB instance to compare the performance of two algorithms in reality. The results show that GA can achieve an acceptable solution in a shorter time for any of the MTSP cases and is more accurate when the data size is small. Meanwhile, SA is more robust and achieves a better solution than GA for complex MTSP cases, but it takes more time to converge. Therefore, the result indicates that it is hard to identify which algorithm is comprehensively superior to the other one. However, It also provides an essential reference to developers who want to choose algorithms to solve MTSP in real life, facilitating them to balance the algorithms performance on different metrics they value.

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Iriani, Rahma Try, Sapti Wahyuningsih e Darmawan Satyananda. "TWO PHASE HEURISTIC ALGORITHM (TPHA) PADA MULTIPLE TRAVELLING SALESMAN PROBLEM (MTSP) DAN IMPLEMENTASI PROGRAMNYA". Jurnal Kajian Matematika dan Aplikasinya (JKMA) 1, n. 1 (17 giugno 2020): 10. http://dx.doi.org/10.17977/um055v1i12020p10-17.

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Multiple Traveling Salesman Problem (MTSP) is one variant of Traveling Salesman Problem (TSP) which involves several salesmen in making a trip to visit several customers. In this article, the Two-Phase Heuristic Algorithm (TPHA) is used to solve MTSP problems. The algorithm classifies customers into several regions using the K-Means algorithm, which will then find a route solution for each region using a genetic algorithm. The MTSP problems that were resolved using TPHA were implemented into the Borland Delphi 7.0 programming language. Application testing was conducted using 21, 32, and 46 point cases.

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BROWN, EVELYN C., CLIFF T. RAGSDALE e ARTHUR E. CARTER. "A GROUPING GENETIC ALGORITHM FOR THE MULTIPLE TRAVELING SALESPERSON PROBLEM". International Journal of Information Technology & Decision Making 06, n. 02 (giugno 2007): 333–47. http://dx.doi.org/10.1142/s0219622007002447.

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The multiple traveling salesperson problem (MTSP) involves scheduling m > 1 salespersons to visit a set of n > m locations. Thus, the n locations must be divided into m groups and arranged so that each salesperson has an ordered set of cities to visit. The grouping genetic algorithm (GGA) is a type of genetic algorithm (GA) designed particularly for grouping problems. It has been successfully applied to a variety of grouping problems. This paper focuses on the application of a GGA to solve the MTSP. Our GGA introduces a new chromosome representation to indicate which salesperson is assigned to each tour and the ordering of the cities within each tour. We compare our method to standard GAs that employ either the one-chromosome or two-chromosome representation for MTSP. This research demonstrates that our GGA with its new chromosome representation is capable of solving a variety of MTSP problems from the literature and can outperform the traditional encodings of previously published GA methods.

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Mercante, Luiza A., Vanessa P. Scagion, Adriana Pavinatto, Rafaela C. Sanfelice, Luiz H. C. Mattoso e Daniel S. Correa. "Electronic Tongue Based on Nanostructured Hybrid Films of Gold Nanoparticles and Phthalocyanines for Milk Analysis". Journal of Nanomaterials 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/890637.

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The use of gold nanoparticles combined with other organic and inorganic materials for designing nanostructured films has demonstrated their versatility for various applications, including optoelectronic devices and chemical sensors. In this study, we reported the synthesis and characterization of gold nanoparticles stabilized with poly(allylamine hydrochloride) (Au@PAH NPs), as well as the capability of this material to form multilayer Layer-by-Layer (LbL) nanostructured films with metal tetrasulfonated phthalocyanines (MTsPc). Film growth was monitored by UV-Vis absorption spectroscopy, atomic force microscopy (AFM), and Fourier transform infrared spectroscopy (FTIR). Once LbL films have been applied as active layers in chemical sensors, Au@PAH/MTsPc and PAH/MTsPc LbL films were used in an electronic tongue system for milk analysis regarding fat content. The capacitance data were treated using Principal Component Analysis (PCA), revealing the role played by the gold nanoparticles on the LbL films electrical properties, enabling this kind of system to be used for analyzing complex matrices such as milk without any prior pretreatment.

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Jin, Hui, Qingsong He, Miao He, Shiqing Lu, Fangchao Hu e Daxian Hao. "Optimization for medical logistics robot based on model of traveling salesman problems and vehicle routing problems". International Journal of Advanced Robotic Systems 18, n. 3 (1 maggio 2021): 172988142110225. http://dx.doi.org/10.1177/17298814211022539.

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Fast medicine dispensing system (FMDS) as a kind of medical logistic robot can dispense many drugs for one prescription at the same time. To guarantee the sustainability of drug dispensation, it is required that FMDS replenish drugs rapidly. The traditional order picking model (OPM) is difficult to meet the demand of prompt replenishment. To solve the problems of prolonged refilling route and inefficiency of drugs replenishment, a mixed refilling model based on multiple steps traveling salesman problem model (MTSPM) and vehicle routing problem model (VRPM) is proposed, and it is deployed in two circumstances of FMDS, including temporary replenishment mode (TRM) and concentrate replenishment mode (CRM). It not only meted the demand under different circumstances of drug replenishment but also shortened the refilling route significantly. First, the new pick sets were generated. Then, the orders of pick sets were optimized and the new paths were achieved. When the number of pickings is varied no more than 20, experiment results declared that the refilling route is the shortest by utilizing MTSPM when working under the TRM condition. Comparing MTSPM with OPM, the rate of refilling route length decreased up to 32.18%. Under the CRM condition, the refilling route is the shortest by utilizing VRPM. Comparing VRPM with OPM, the rate of refilling route length decreased up to 58.32%. Comparing VRPM with MTSPM, the rate of refilling route length has dropped more than 43.26%.

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Più fonti

Tesi sul tema "Mtspo"

Saade, Christelle. "Structure and function in solution of the transmembrane protein mTSPO in different amphiphilic systems : from detergents to biomimetic environments". Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF038.

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TSPO est une petite protéine membranaire translocatrice, ubiquitaire, composée de cinq hélices-α transmembranaires. Chez les mammifères, elle est principalement localisée dans la membrane externe des mitochondries, où elle jouerait un rôle dans le transport du cholestérol et la voie de synthèse des stéroïdes. Cette protéine présente un intérêt pharmacologique majeur en raison de sa forte affinité pour de nombreux ligands utilisés comme marqueurs de l'inflammation en neuro-imagerie. La seule structure atomique connue des TSPOs de mammifères est la structure RMN (2MGY.PDB) de la TSPO de souris (mTSPO). Cependant, cette structure est controversée, car obtenue en repliant la protéine dans une concentration forte de détergent DPC et en présence du ligand (R)-PK11195, qui la rigidifie fortement. En l'absence de ligand, la structure de mTSPO est trop flexible pour être résolue par RMN. De plus, à ce jour, aucune condition amphiphile n'a permis de cristalliser les TSPOs de mammifères, avec ou sans ligand, contrairement aux TSPOs bactériennes.L'objectif de cette étude est de déterminer, par une approche structure/fonction, l'effet de différents environnements amphiphiles sur la structure de mTSPO en condition “apo” (i.e. sans ligand). Nous avons sondé sa structure en solution à différentes échelles par des techniques de diffusion de rayonnement et de spectroscopie optique. En particulier, la diffusion de rayons X et de neutrons aux petits angles (SAXS et SANS), combinée à la chromatographie d'exclusion stérique (SEC), la variation de contraste en SANS et la modélisation ab initio, a permis d'obtenir la conformation du complexe entier mTSPO/amphiphiles et de sonder spécifiquement celles de la protéine et de la bouée d'amphiphiles. La quantité de molécules d'amphiphiles associés à mTSPO, mesurée par MALLS, a permis de valider les modèles proposés. L'effet de l'environnement sur l'affinité du ligand a été mesuré par thermophorèse à micro-échelle (MST).L'apo-mTSPO, produite par voie recombinante dans les corps d'inclusion de la bactérie E. coli, est partiellement dépliée suite à son extraction par le SDS. Nous montrons que la protéine se replie en DPC à la fois au niveau local (augmentation significative de la quantité et des interactions des hélices-α et de la fluorescence des tryptophanes) et au niveau tridimensionnel avec une conformation “apo” plus étendue que la structure RMN 2MGY.PDB. En ajoutant des phospholipides DMPC, pour obtenir un environnement de bicelles mixtes DMPC:DPC partiellement biomimétique, l'apo-mTSPO se structure davantage : la quantité d'hélices-α et leurs interactions augmentent significativement, ainsi que la fluorescence des tryptophanes. Ce repliement est associé à une augmentation significative de l'affinité de la protéine pour le ligand (R)-PK11195 (0.9 µM) comparée à celle en DPC (70 µM) et SDS (absence d'affinité). Nous démontrons ainsi la pertinence de l'utilisation de bicelles DMPC:DPC pour l'étude en solution des protéines membranaires et confirmons le rôle crucial des lipides dans la structure et la fonction de mTSPO. Enfin, nous montrons que cet environnement est favorable à la cristallisation de l'apo-mTSPO et à la reconstitution de la protéine dans des nanodisques de DMPC.Pour comparer ces résultats avec une protéine exprimée en condition native, nous avons développé un nouveau protocole de production de mTSPO en levures. Nous avons réussi à purifier la protéine en condition “apo” en DDM, un détergent connu pour solubiliser les protéines correctement repliées tout en conservant des lipides membranaires associés. Ces travaux de thèse (i) contribuent à une meilleure compréhension de la structure/fonction de mTSPO dans différents environnements amphiphiles, pour déterminer les conditions optimales à des études structurales à plus haute résolution, et (ii) constituent un apport méthodologique significatif pour l'étude des protéines membranaires en solution
TSPO is a small, ubiquitous, translocator membrane protein composed of five transmembrane α-helices. In mammals, it is primarily located in the outer mitochondrial membrane, where it is believed to play a role in cholesterol transport and steroid synthesis pathways. This protein has significant pharmacological interest due to its affinity for various ligands used as markers of inflammation in neuroimaging. The only known atomic structure of mammalian TSPOs is the NMR structure (2MGY.PDB) of mouse TSPO (mTSPO). However, this structure is controversial as it was obtained by refolding the protein using a high concentration of DPC and in the presence of the ligand (R)-PK11195, that stiffens it significantly. In the absence of ligand, the structure of mTSPO is too flexible to be resolved by NMR. Furthermore, to date, no amphiphilic condition has allowed the crystallization of mammalian TSPOs, with and without ligand, unlike bacterial TSPOs.The aim of the present study is to determine, using a structure/function approach, the effect of different amphiphilic environments on the structure of apo-mTSPO (i.e. without the ligand). We investigated mTSPO's structure in solution at different scales using radiation scattering and optical spectroscopy techniques. Small-angle X-ray and neutron scattering (SAXS, SANS), combined with size-exclusion chromatography (SEC), contrast variation in SANS, and ab initio modeling, allowed us to obtain the conformation of the entire mTSPO/amphiphile complex and to specifically probe those of the protein and the amphiphilic belt within the complex. The quantity of amphiphile molecules associated with mTSPO, measured by MALS, allowed the validation of the proposed models. The effect of the environment on ligand affinity was measured by microscale thermophoresis (MST).The apo-mTSPO, produced by a recombinant way in E.coli bacteria inclusion bodies, is partially unfolded following its extraction by SDS. We show that the protein refolds in DPC, both locally (significant increase of content and interactions of α-helices and in tryptophan fluorescence) and three-dimensionally, with a more extended "apo" conformation than the NMR structure 2MGY.PDB. Adding DMPC phospholipids to create a partially biomimetic environment of mixed DMPC:DPC bicelles further structures apo-mTSPO: the quantity and interactions of α-helices, as well as tryptophan fluorescence, increase significantly. This refolding is associated with a significant increase in the protein's affinity for the ligand (R)-PK11195 (0.9 μM) compared to that in DPC (70 μM) and SDS (no affinity). Thus, we demonstrate the relevance of using DMPC:DPC bicelles for studying membrane proteins in solution and confirm the crucial role of lipids in the structure and function of mTSPO. Finally, we show that this environment is favorable for the crystallization of apo-mTSPO and for reconstituting the protein in DMPC nanodiscs.To compare these results with a protein expressed under native conditions, we developed a new protocol for producing mTSPO in yeast cells. We managed to purify the protein in “apo” condition in DDM, a detergent known for solubilizing properly folded proteins, while retaining associated membrane lipids.This thesis work (i) contributes to a better understanding of the structure/function of mTSPO in different amphiphilic environments to determine optimal conditions for higher-resolution structural studies, and (ii) provides a significant methodological contribution to the study of membrane proteins in solution

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Sørensen, Per K. Tshaṅs-dbyaṅs-rgya-mtsho. "Divinity secularized : an inquiry into the nature and form of the songs ascribed to the sixth Dalai Lama /". Wien : Arbeitskreis für tibetische und buddhistische Studien, Universität Wien, 1990. http://catalogue.bnf.fr/ark:/12148/cb394429123.

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Jiang, Chunyu. "DATA MINING AND ANALYSIS ON MULTIPLE TIME SERIES OBJECT DATA". Wright State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=wright1177959264.

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Na, Byungsoo. "Heurisic approaches for no-depot k-traveling salesmen problem with a minmax objective". Texas A&M University, 2003. http://hdl.handle.net/1969.1/5825.

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This thesis deals with the no-depot minmax Multiple Traveling Salesmen Problem (MTSP), which can be formulated as follows. Given a set of n cities and k salesmen,find k disjoint tours (one for each salesmen) such that each city belongs to exactly one tour and the length of the longest of k tours is minimized. The no-depot assumption means that the salesmen do not start from and return to one fixed depot. The no-depot model can be applied in designing patrolling routes, as well as in business situations, especially where salesmen work from home or the company has no central office. This model can be also applied to the job scheduling problem with n jobs and k identical machines. Despite its potential applicability to a number of important situations, the research literature on the no-depot minmax k-TSP has been limited, with no reports on computational experiments. The previously published results included the proof of NP-hardness of the problem of interest, which motivates using heuristics for its solution. This thesis proposes several construction heuristic algorithms, including greedy algorithms, cluster first and route second algorithms, and route first and cluster second algorithms. As a local search method for a single tour, 2-opt search and Lin-Kernighan were used, and for a local search method between multiple tours, relocation and exchange (edge heuristics) were used. Furthermore, to prevent the drawback of trapping in the local minima, the simulated annealing method is used. Extensive computational experiments were carried out using TSPLIB instances. Among construction algorithms, route first and cluster second algorithms including removing two edges method performed best. In terms of running time, clustering first and routing second algorithms took shorter time on large-scale instances. The simulated annealing could produce better solutions than the descent method, but did not always perform well in terms of average solution. To evaluate the performance of the proposed heuristic methods, their solutions were compared with the optimal solutions obtained using a mixed-integer programming formulation of the problem. For small-scale problems, heuristic solutions were equal to the optimal solution output by CPLEX.

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Fraccaroli, Eduardo Sacogne. "Alocação de tarefas para a coordenação de robôs heterogêneos aplicados a agricultura de precisão". Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/55/55134/tde-24072018-145007/.

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O Brasil é uma referência mundial na produção e exportação de citros, entretanto esse cultivo pode sofrer diversos problemas e perdas de produtividade por motivos diversos, como por exemplo, pragas. Para reduzir os riscos e perdas, torna-se interessante o uso de sistemas automatizados de monitoramento, justificando a necessidade de realizar a coleta de dados para determinar diversos fatores. Determinadas plantações, como a de citros, não podem ser monitoradas somente via solo ou somente via imagens aéreas, tornando necessário mesclar ambas as abordagens de acordo com o parâmetro a ser monitorado. Para a realização desse monitoramento devem ser utilizados robôs com habilidades distintas, robôs aéreos e robôs terrestres. Assim, é preciso designar as tarefas que cada robô realizará e também coordenar todos os robôs durante a execução do sistema como um todo, visando otimizar o processo de coleta de dados. Esse problema pode ser analisado e modelado como um problema de alocação de tarefas para robôs (Multi-Robot Task Allocation (MRTA)). Para resolver esse problema propõe-se um framework baseado em técnicas de cobertura de conjuntos e em mecanismo de mercado baseado em leilão. Teste simulados são realizados e demonstram que a presente proposta cumpre o papel na alocação das tarefas aos robôs. Além disso, visando a aplicação da solução proposta é projetado e desenvolvido uma plataforma robótica aérea (quadrirotor) de baixo custo utilizando peças prototipadas. Para o controle de estabilidade dessa plataforma, propõe-se um modelo matemático de acordo com os parâmetros inerciais do quadrirotor. Esse quadrirotor é utilizado em diversas aplicações reais, mostrando que o projeto desenvolvido pode ser reproduzido e destinado a execução de tarefas reais, como por exemplo a coleta de dados na agricultura de precisão.
Brazil is a world reference in the production and export of citrus, although this crop can suffer several problems and losses of productivity for diverse reasons, as for example, pests. In order to reduce risks and losses, it is interesting to use automated monitoring systems, justifying the need to perform data collection to determine several factors. Certain plantations, such as citrus plantations, can not be monitored only via soil or only via aerial images, making it necessary to merge both approaches according to the parameter to be monitored. To perform this monitoring, robots with different abilities, such asunmanned aerial vehicle (UAV) and unmanned ground vehicle (UCV) should be used. Therefore, it is necessary to assign the tasks that each robot will perform and also to coordinate all the robots during the execution of the system as a whole, in order to optimize the process of data collection. The problem can be studied and modeled as a task allocation problem for robots (MRTA). To solve this problem we propose a framework based set covering techniques and auction-based market mechanism. Simulated tests are performed and demonstrate that the present proposal fulfills the role in assigning tasks to robots. In addition, aiming at the application of the proposed solution is designed and developed a low cost aerial robotic platform (quadrirotor) which use prototyped parts. This quadrirotor is used in several real applications, showing that the developed project can be reproduced and destined to perform real tasks, such as data collection in precision agriculture.

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Ng, Hang-pong, e 伍恆邦. "Development of murine model of autoimmune thyroiditis induced with homologous thyroid peroxidase and evaluation of immune tolerance in atransgenic mice that overexpress mTPO in the thymus". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B35772554.

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Ng, Hang-pong. "Development of murine model of autoimmune thyroiditis induced with homologous thyroid peroxidase and evaluation of immune tolerance in a transgenic mice that overexpress mTPO in the thymus". Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B35772554.

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Deshayes, Laurent. "La mission du Tibet". Nantes, 2001. http://www.theses.fr/2001NANT3025.

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Abstract (sommario):

Fondée en 1846, la Mission du Tibet fut confiée aux prêtres de la Société des Missions Étrangères de Paris. Ils tentèrent de pénétrer au Tibet, sans succès, et s'installèrent dans les Marches tibétaines (Sichuan, Yunnan), et dans le sud du Sikkim. Durant plus d'un siècle, sous cinq épiscopats, les religieux furent les témoins, les victimes et parfois les acteurs d'événements politiques opposant Pékin et Lhassa. Ils furent aussi l'avant-garde de la France au coeur de l'Asie. Ce fut d'abord le temps des pionniers : Mgrs ThomineDesmazures (1857-1864), Chauveau (1864-1877) et Biet (1877-1901) lancèrent de vaines expéditions vers le Toit du monde et furent confrontés, dans les Marches tibétaines, au pouvoir des monastères bouddhistes et des seigneurs locaux. Puis, grâce à Mgr Giraudeau (1901-1936), à la faveur du soulèvement des populations tibétaines (1905), et malgré les demandes d'alliance faites par le Xllle Dalai Lama, la France espéra renforcer ses liens avec la Chine impériale.

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Straijer, Flak Adriana. "El valor fundacional de una autobiografía: My Land and my People (1962) del XIV Dalai Lama". Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/285728.

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La tesis analiza el corpus biográfico familiar y lo contrasta con el corpus biográfico generado asimismo por la figura del Dalai Lama (Takster, 1935). El objeto es demostrar el carácter seminal de “Mi vida y mi pueblo” (1962), epicentro textual de toda la auto/biografía posterior. Las tres autobiografías escritas por el Dalai Lama entre 1962 y 2009, son: “Mi vida y mi pueblo. Memorias del Premio Nobel de la Paz 1989, Libertad en el exilio. Autobiografía del Dalai Lama, y Mi biografía espiritual. A cargo de Sofía Stril – Rever. Asimismo, el Dalai Lama es protagonista de sucesivas biografías desde 1984 iniciadas con Great Ocean. Authorized biography of the Dalai Lama, hasta el presente, siempre con una colaboración occidental que hace accesible su relato a la comunidad internacional
The thesis analyzes the familiar biographical corpus and contrasts with the biographical corpus also generated by the figure of the Dalai Lama (Takster, 1935). The purpose is to demonstrate the seminal character of My Life and my People (1962), textual epicenter of all auto/biography back. The three autobiographies written by the Dalai Lama between 1962 and 2009, are: My Life and my People. Memoirs of the Dalai Lama of Tibet, Freedom in Exile. Autobiography of the Dalai Lama, and My spiritual biography. With Sofia Stril – Rever. Also, the Dalai Lama is the protagonist of successive biographies since 1984 started with Great Ocean. Authorized biography of the Dalai Lama, until now, always with a Western collaboration that makes his story accessible to the international community.

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Prince, Raphaëlle. "La démocratisation du gouvernement tibétain en exil de 1990 à 2013". Master's thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/25756.

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Ce mémoire a pour objectif d’étudier la démocratisation du gouvernement tibétain en exil de 1991 à 2013. Il vise à éclaircir les défis singuliers d’un gouvernement en exil dans ses efforts de démocratisation. En reliant les travaux sur la démocratisation de Dahl et sur les gouvernement en exil de Shain au contexte très particulier de la communauté tibétaine exilée, nous avons tenté d’éclaircir le paradoxe apparent entre un gouvernement par essence transitoire, le gouvernement en exil, et une transition démocratique, permettant une meilleure stabilité institutionnelle. Une attention particulière a été portée au contexte socioculturel tibétain, car le processus de démocratisation ne saurait être compris sans un souci du milieu qui l’accueille et l’a fait naître. En ce sens, nous avons tenté de mettre comprendre la structure politique avant l’exil, le gouvernement central de Lhassa, ainsi que les obstacles et les moteurs contextuels de la démocratisation du gouvernement tibétain en exil. Le conservatisme du gouvernement tibétain en exil, la participation politique tibétaine confrontée à l’imposante figure du dalaï-lama, le bouddhisme et finalement les institutions politiques de l’exil nous ont semblé autant d’obstacles aux élans démocratiques du gouvernement en exil. Malgré ces freins, d’autres facteurs encouragent au contraire la démocratisation du gouvernement, dont les organisations non gouvernementales indépendantistes tibétaines en exil, qui s’engagent dans le débat politique, la toile virtuelle offrant une plateforme d’échange et de débats accessible à l’ensemble de la diaspora tibétaine, les initiatives du gouvernement tibétains en exil en faveur de sa démocratisation institutionnelle remarquable et finalement la diaspora tibétaine, lentement actrice engagée dans la politique de son gouvernement en exil. En nous appuyant sur les indicateurs de démocratisation de Robert Allan Dhal nous avons pu remarquer que la démocratisation du gouvernement tibétain en exil de 1990 à 2013 s’est développée sensiblement. Ainsi, les deux indicateurs de démocratisation, la libéralisation et l’inclusion politique, ont été plus importants durant cette période, quoique les défis semblent encore bien présents en 2013. Afin d’approfondir les liens qu’entretiennent le gouvernement tibétain en exil et la communauté internationale durant notre période d’analyse, une étude de cas relative à l’appui de la communauté européenne envers le gouvernement tibétain en exil conclu notre recherche.

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Libri sul tema "Mtspo"

Cunrong, Ye, Haibei Zangzu Zizhizhou (China) e Zhongguo gong chan dang. Haibei Zangzu Zizhizhou wei yuan hui., a cura di. Haibei =: Mtsho byaṅ. [Xining Shi]: Qinghai ren min chu ban she, 1988.

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Hainan Zangzu Zizhizhou san tao ji cheng ban gong shi. Mtsho-lhoʼi dmangs glu. [Gonghe]: [Hainan Zangzu Zizhizhou san tao ji cheng ban gong shi], 1992.

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Hainan Zangzu Zizhizhou san tao ji cheng ban gong shi. Mtsho-lhoʼi gtam rgyud. [Gonghe]: [Hainan Zangzu Zizhizhou san tao ji cheng ban gong shi], 1992.

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Hainan Zangzu Zizhizhou san tao ji cheng ban gong shi. Mtsho-lhoʼi gtam dpe. [Gonghe]: [Hainan Zangzu Zizhizhou san tao ji cheng ban gong shi], 1992.

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Qiejiang. Mtsho-mo'i rna lung. Zi-ling: Mtsho-sngon Mi-rigs dpe-skrun-khang, 2017.

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nor bu kun grub/, 19uu, a cura di. mngon brjod khungs btsun rgya mtsho. Pe cin: Krung go'i bod rig pa dpe skrun khang, 2010.

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Gnas-brtan-tshe-riṅ. Bod glu nor buʼi rgya mtsho. Lanzhou: Kan-suʼu mi rigs dpe skrun khang, 2008.

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Classics, Institute of Tibetan, a cura di. Ri chos ṅes don rgya mtsho. Ldi-li: Bod-kyi Gtsug-lag Źib-dpyod-khaṅ nas dpar skrun źus, 2013.

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Gesangduojie. Sprin gyi nyams ʼgyur padmaʼi mtsho. Zi-ling: Mtsho-sngon mi rigs dpe skrun khang, 2018.

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Center, Buddhist Digital Resource. Gsung ʼbum blo bzang ʼjam dbyangs rgya mtsho. [Sku 'bum ]: Sku ʼbum byams pa gling, 2000.

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Capitoli di libri sul tema "Mtspo"

Schwieger, Peter. "Tshangs-dbyangs rgya-mtsho". In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_22648-1.

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Grönbold, Günter. "Tshangs-dbyangs rgya-mtsho: mGul glu". In Kindlers Literatur Lexikon (KLL), 1–2. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_22649-1.

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Schwieger, Peter. "Ngag-dbang blo-bzang rgya-mtsho". In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_16836-1.

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Yan, Zhen. "Sde Srid Sangs Rgyas Rgya Mtsho". In Encyclopaedia of the History of Science, Technology, and Medicine in Non-Western Cultures, 3909–11. Dordrecht: Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-007-7747-7_8967.

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de Castro Pereira, Sílvia, E. J. Solteiro Pires e P. B. de Moura Oliveira. "A Hybrid Approach GABC-LS to Solve mTSP". In Communications in Computer and Information Science, 520–32. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-23236-7_36.

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Bishnoi, Suman, Shubham Gupta, Deepak Bhatia e Riyaz Ahmed. "45 nm CMOS-Based MTSPC DFF Design for High Frequency Operation". In Proceedings of the Third International Conference on Information Management and Machine Intelligence, 409–16. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-2065-3_44.

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Lu, Zhanqing, Kai Zhang, Juanjuan He e Yunyun Niu. "Applying K-means Clustering and Genetic Algorithm for Solving MTSP". In Bio-inspired Computing – Theories and Applications, 278–84. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-3614-9_34.

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Zhou, Huiren, e Yinghui Wei. "Optimization of Minimum Completion Time MTSP Based on the Improved DE". In Lecture Notes in Computer Science, 489–98. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13495-1_60.

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Hao, Junling. "Preliminary Analysis on the Relative Solution Space Sizes for MTSP with Genetic Algorithm". In Communications in Computer and Information Science, 649–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-18129-0_98.

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Chen, Guan-Nan, Chiung-Ying Wang e Ren-Hung Hwang. "MTSP: Multi-hop Time Synchronization Protocol for IEEE 802.11 Wireless Ad Hoc Network". In Wireless Algorithms, Systems, and Applications, 664–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11814856_62.

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Atti di convegni sul tema "Mtspo"

Li, Wenhao, Shishun Zhang, Sisi Dai, Hui Huang, Ruizhen Hu, Xiaohong Chen e Kai Xu. "Synchronized Dual-arm Rearrangement via Cooperative mTSP". In 2024 IEEE International Conference on Robotics and Automation (ICRA), 9242–48. IEEE, 2024. http://dx.doi.org/10.1109/icra57147.2024.10610424.

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Zehua, Yue. "MTSP UAV Detection Problem Based on Ant Algorithm". In 2018 17th International Symposium on Distributed Computing and Applications for Business Engineering and Science (DCABES). IEEE, 2018. http://dx.doi.org/10.1109/dcabes.2018.00075.

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Liu, Caifeng, e Yanxia Zhang. "Research on MTSP Problem based on Simulated Annealing". In ICISS '18: 2018 International Conference on Information Science and System. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3209914.3234638.

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Al-Omeer, Maha Ata, e Zakir Hussain Ahmed. "Comparative study of crossover operators for the MTSP". In 2019 International Conference on Computer and Information Sciences (ICCIS). IEEE, 2019. http://dx.doi.org/10.1109/iccisci.2019.8716483.

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Lu, Li-Chih, e Tai-Wen Yue. "Mission-Oriented Ant-Team ACO for Min-Max MTSP". In 2017 International Conference on Information, Communication and Engineering (ICICE). IEEE, 2017. http://dx.doi.org/10.1109/icice.2017.8478886.

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Wang, Ziqiao. "Application of MTSP in the transport of Ebola vaccine". In 3rd International Conference on Management Science, Education Technology, Arts, Social Science and Economics. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/msetasse-15.2015.275.

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Ramanathan, Thanya, Sujith Suresh e T. Srinivas Rao. "Multiple Depot MTSP using Genetic Algorithm and Reinforcement Learning". In 2023 Second International Conference on Augmented Intelligence and Sustainable Systems (ICAISS). IEEE, 2023. http://dx.doi.org/10.1109/icaiss58487.2023.10250669.

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Xu, Yingkai, Shan Kang e Hui Lin. "The MTSP optimal model suited for local-cross repeat path". In 2013 25th Chinese Control and Decision Conference (CCDC). IEEE, 2013. http://dx.doi.org/10.1109/ccdc.2013.6561558.

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Hong-li, Xu, e Zhang Cheng-Ming. "The Research about Balanced Route MTSP Based on Hybrid Algorithm". In 2009 International Conference on Communication Software and Networks. IEEE, 2009. http://dx.doi.org/10.1109/iccsn.2009.115.

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Ma, Jianxin, Shuo Shi e Xuemai Gu. "An Optimization-based mTSP Clustering Algorithm for Wireless Sensor Networks". In 2018 14th International Wireless Communications & Mobile Computing Conference (IWCMC). IEEE, 2018. http://dx.doi.org/10.1109/iwcmc.2018.8450272.

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