Letteratura scientifica selezionata sul tema "Mitochondrial DNA"
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Articoli di riviste sul tema "Mitochondrial DNA"
Faria, Rúben, Eric Vivés, Prisca Boisguerin, Angela Sousa e Diana Costa. "Development of Peptide-Based Nanoparticles for Mitochondrial Plasmid DNA Delivery". Polymers 13, n. 11 (1 giugno 2021): 1836. http://dx.doi.org/10.3390/polym13111836.
Testo completoBasu, Urmimala, Alicia M. Bostwick, Kalyan Das, Kristin E. Dittenhafer-Reed e Smita S. Patel. "Structure, mechanism, and regulation of mitochondrial DNA transcription initiation". Journal of Biological Chemistry 295, n. 52 (30 ottobre 2020): 18406–25. http://dx.doi.org/10.1074/jbc.rev120.011202.
Testo completoCampbell, C. L., e P. E. Thorsness. "Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments". Journal of Cell Science 111, n. 16 (15 agosto 1998): 2455–64. http://dx.doi.org/10.1242/jcs.111.16.2455.
Testo completoHerrmann, J. M., R. A. Stuart, E. A. Craig e W. Neupert. "Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA." Journal of Cell Biology 127, n. 4 (15 novembre 1994): 893–902. http://dx.doi.org/10.1083/jcb.127.4.893.
Testo completoVarma, V. A., C. M. Cerjan, K. L. Abbott e S. B. Hunter. "Non-isotopic in situ hybridization method for mitochondria in oncocytes." Journal of Histochemistry & Cytochemistry 42, n. 2 (febbraio 1994): 273–76. http://dx.doi.org/10.1177/42.2.8288868.
Testo completoHabbane, Mouna, Julio Montoya, Taha Rhouda, Yousra Sbaoui, Driss Radallah e Sonia Emperador. "Human Mitochondrial DNA: Particularities and Diseases". Biomedicines 9, n. 10 (1 ottobre 2021): 1364. http://dx.doi.org/10.3390/biomedicines9101364.
Testo completoHong, Seongho, Sanghun Kim, Kyoungmi Kim e Hyunji Lee. "Clinical Approaches for Mitochondrial Diseases". Cells 12, n. 20 (20 ottobre 2023): 2494. http://dx.doi.org/10.3390/cells12202494.
Testo completoWang, Sheng-Fan, Shiuan Chen, Ling-Ming Tseng e Hsin-Chen Lee. "Role of the mitochondrial stress response in human cancer progression". Experimental Biology and Medicine 245, n. 10 (23 aprile 2020): 861–78. http://dx.doi.org/10.1177/1535370220920558.
Testo completoBradshaw, Patrick C., e David C. Samuels. "A computational model of mitochondrial deoxynucleotide metabolism and DNA replication". American Journal of Physiology-Cell Physiology 288, n. 5 (maggio 2005): C989—C1002. http://dx.doi.org/10.1152/ajpcell.00530.2004.
Testo completoBertrand, Helmut. "Senescence is coupled to induction of an oxidative phosphorylation stress response by mitochondrial DNA mutations in Neurospora". Canadian Journal of Botany 73, S1 (31 dicembre 1995): 198–204. http://dx.doi.org/10.1139/b95-246.
Testo completoTesi sul tema "Mitochondrial DNA"
Al, Amir Dache Zahra. "Étude de la structure de l'ADN circulant d'origine mitochondriale". Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT059.
Testo completoPlasma transports blood cells with a mixture of compounds, including nutrients, waste, antibodies, and chemical messengers...throughout the body. Non-soluble factors such as circulating DNA and extracellular vesicles have recently been added to the list of these components and have been the subject of extensive research due to their role in intercellular communication. Circulating DNA (cirDNA) is composed of cell-free and particle-associated DNA fragments, which can be released by all cell types. cirDNA is derived not only from genomic DNA but also from extrachromosomal mitochondrial DNA. Numerous studies carried out lately indicate that the quantitative and qualitative analysis of cirDNA represents a breakthrough in clinical applications as a non-invasive biomarker for diagnosis, prognosis and therapeutic follow-up. However, despite the promising future of cirDNA in clinical applications, particularly in oncology, knowledge regarding its origins, composition and functions, that could considerably optimize its diagnostic value, is still lacking.The main goal of my thesis was to identify and characterize the structural properties of extracellular DNA of mitochondrial origin. By examining the integrity of this DNA, as well as the size and density of associated structures, this work revealed the presence of dense particles larger than 0.2 µm containing whole mitochondrial genomes. We characterized these structures by electron microscopy and flow cytometry and identified intact mitochondria in the extracellular medium in vitro and ex vivo (in plasma samples from healthy individuals). Oxygen consumption by these mitochondria was detected by the Seahorse technology, suggesting that at least some of these intact extracellular mitochondria may be functional.In addition, I contributed to other studies carried out in the team, such as studies aiming at evaluating (1) the influence of pre-analytical and demographic parameters on the quantification of nuclear and mitochondrial cirDNA on a cohort of 104 healthy individuals and 118 patients with metastatic colorectal cancer, (2) the influence of hypoxia on the release of cirDNA in vitro and in vivo, and (3) the potential of cirDNA analysis in the early detection and screening of cancer.This manuscript present a recent review on cirDNA and its different mechanisms of release, which go hand in hand with the structural characterization of this DNA, its functional aspects and its clinical applications. In addition, this thesis provides new knowledge on the structure of extracellular mitochondrial DNA and opens up new avenues for reflection, particularly on the potential impact that could have those circulating mitochondria on cell-cell communication, inflammation and clinical applications
Berg, Alonso Laetitia. "Déficits de la chaîne respiratoire mitochondriale avec instabilité de l’ADN mitochondrial : identification de nouveaux gènes et mécanismes". Thesis, Université Côte d'Azur (ComUE), 2016. http://www.theses.fr/2016AZUR4101/document.
Testo completoNon communiqué
Rebelo, Adriana. "Probing Mitochondrial DNA Structure with Mitochondria-Targeted DNA Methyltransferases". Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/344.
Testo completoBoyer, Hélène. "The mamalian circadian clock regulates the abundance and expression of mitochondrial DNA in the nuclear compartment". Thesis, Lyon, 2020. http://www.theses.fr/2020LYSEN015.
Testo completoThe mitochondrial genome is minimal and most of the mitochondrial proteins are encoded in the nuclear genome. Thus, although mitochondrial and nuclear genomes are physically separated in the cell, anterograde (nuclear to mitochondrial) and retrograde (mitochondrial to nuclear) signals are essential for mitochondrial biogenesis to be coordinated with the cellular energetic demands. Those demands are cyclical in nature, and the circadian clock regulates numerous aspects of mitochondrial biology, including the dynamics of fusion and fission that shape the architecture of the mitochondrial network. In murine livers, the network oscillates between fused (during the day) and fragmented structures (during the night). A fused network is associated with a more efficient ATP production whereas fragmentation is associated with elevated mitochondrial ROS levels and mitophagy. In other words, if mtDNA was to ever escape mitochondria, fission would help. Complementation experiments in yeast have shown that mitochondrial DNA (mtDNA) is able to escape from the mitochondria and enter the nucleus. In human cells (HeLa), the intact and full-length mitochondrial genome has been detected in the nucleus. Evolutionary analyses of nuclear inserted mitochondrial sequences (numts) suggest an ongoing process of integration of mitochondrial sequences into the nuclear genome. Also, abundant somatically acquired mitochondrial- nuclear genome fusion events (simts) have been shown to occur in human cancer cells - an extreme context of genomic instability and disrupted circadian rhythms. The availability of mtDNA in the cytoplasm, protected by vesicles, to be taken up by the nucleus is thought to result from mitophagy. As mitophagy and mitochondrial dynamics are regulated by the circadian clock, we investigated whether mtDNA would accumulate in the nuclear compartment as a function of circadian time. We addressed this question in the mouse liver, a differentiate mammalian tissue. This work demonstrates that the nuclear abundance of mtDNA in murine livers is regulated by the circadian clock – with a zenith at the end of the circadian night. Nuclear mtDNA is differentially hydroxymethylated relative to the total mtDNA extracted from the same tissue. Also, circadian clock disruption altered the phase and abundance of nuclear mtDNA. Additionally, we observed that concurrent accumulation of nuclear mtRNA was sensitive to nutritional challenges. Probably, these dynamics are driven by mitochondrial network remodeling dynamics. Increased nuclear presence and insertions of mtDNA in cancer cells or aging tissues, which are often associated with disrupted circadian oscillators- may thus arise from the loss of a physiological rhythm in mitochondrial-network remodeling
Korhonen, Jenny. "Functional and structural characterization of the human mitochondrial helicase /". Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-102-2/.
Testo completoBerg, Alonso Laetitia. "Déficits de la chaîne respiratoire mitochondriale avec instabilité de l’ADN mitochondrial : identification de nouveaux gènes et mécanismes". Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2016. http://www.theses.fr/2016AZUR4101.
Testo completoNon communiqué
Weber, Katharina Karin. "Studies of mitochondrial DNA". Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295072.
Testo completoMyers, K. A. "Alkylation of mitochondrial DNA". Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234216.
Testo completoJohansson, Jennie. "Epigenetic Regulation of Mitochondrial DNA". Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-166684.
Testo completoWertzler, Kelsey Janel. "High mobility group A1 and mitochondrial transcription factor A compete for binding to mitochondrial DNA". Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Thesis/Summer2009/k_wertzler_051409.pdf.
Testo completoTitle from PDF title page (viewed on July 21, 2009). "School of Molecular Biosciences." Includes bibliographical references.
Libri sul tema "Mitochondrial DNA"
Copeland, William C. Mitochondrial DNA. New Jersey: Humana Press, 2002. http://dx.doi.org/10.1385/1592592848.
Testo completoStuart, Jeffrey A., a cura di. Mitochondrial DNA. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-521-3.
Testo completoMcKenzie, Matthew, a cura di. Mitochondrial DNA. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3040-1.
Testo completoNicholls, Thomas J., Jay P. Uhler e Maria Falkenberg, a cura di. Mitochondrial DNA. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2922-2.
Testo completoJohn, Justin C. St. Mitochondrial DNA, mitochondria, disease, and stem cells. New York: Humana Press, 2013.
Cerca il testo completoSt. John, Justin C., a cura di. Mitochondrial DNA, Mitochondria, Disease and Stem Cells. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-101-1.
Testo completoS, DiMauro, e Wallace Douglas C, a cura di. Mitochondrial DNA in human pathology. New York: Raven Press, 1993.
Cerca il testo completoJames, Holt Ian, a cura di. Genetics of mitochondrial diseases. Oxford: Oxford University Press, 2003.
Cerca il testo completoSun, Hongzhi, e Xiangdong Wang, a cura di. Mitochondrial DNA and Diseases. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-6674-0.
Testo completoA, Dudareva N., e Salganik, R. I. (Rudolʹf Iosifovich), a cura di. Mitokhondrialʹnyĭ genom. Novosibirsk: "Nauka," Sibirskoe otd-nie, 1990.
Cerca il testo completoCapitoli di libri sul tema "Mitochondrial DNA"
Mainieri, Avantika. "Mitochondrial DNA". In Encyclopedia of Evolutionary Psychological Science, 1–4. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-16999-6_2229-1.
Testo completoVerma, Mukesh, e Deepak Kumar. "Mitochondrial DNA". In Encyclopedia of Cancer, 1–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_3765-2.
Testo completoVerma, Mukesh, e Deepak Kumar. "Mitochondrial DNA". In Encyclopedia of Cancer, 2867–70. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-46875-3_3765.
Testo completoMishra, Alaknanda. "Mitochondrial DNA". In Encyclopedia of Animal Cognition and Behavior, 4329–32. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-319-55065-7_162.
Testo completoVerma, Mukesh, e Deepak Kumar. "Mitochondrial DNA". In Encyclopedia of Cancer, 2331–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_3765.
Testo completoMishra, Alaknanda. "Mitochondrial DNA". In Encyclopedia of Animal Cognition and Behavior, 1–4. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47829-6_162-1.
Testo completoMainieri, Avantika. "Mitochondrial DNA". In Encyclopedia of Evolutionary Psychological Science, 5150–52. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-19650-3_2229.
Testo completoGojobori, Jun. "Mitochondrial DNA". In Evolution of the Human Genome II, 103–20. Tokyo: Springer Japan, 2021. http://dx.doi.org/10.1007/978-4-431-56904-6_4.
Testo completoReynier, P., Y. Malthièry e P. Lestienne. "Mitochondrial DNA Analysis". In Mitochondrial Diseases, 379–87. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-59884-5_28.
Testo completoCasane, D., e M. Guéride. "Mitochondrial DNA Inheritance in Mammals". In Mitochondrial Diseases, 17–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-59884-5_3.
Testo completoAtti di convegni sul tema "Mitochondrial DNA"
Joseph Mathuram, T. L., Y. Su, M. Hatzoglou, Y. Perry, Y. Wu e A. Blumental-Perry. "Mitochondria-to-Nucleus Retrograde Signaling Via Mitochondrial DNA Encoded Non-coding RNA Regulates Mitochondrial Bioenergetics". In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4400.
Testo completoCristea, Paul Dan, e Rodica Tuduce. "Mitochondrial DNA Analysis Using Genomic Signals". In 2009 16th International Conference on Systems, Signals and Image Processing. IEEE, 2009. http://dx.doi.org/10.1109/iwssip.2009.5367711.
Testo completoNesbitt, V., e R. McFarland. "G259 Mitochondrial DNA disease in children". In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference and exhibition, 13–15 May 2019, ICC, Birmingham, Paediatrics: pathways to a brighter future. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2019. http://dx.doi.org/10.1136/archdischild-2019-rcpch.251.
Testo completoXu, W., R. Chen, B. Hu, J. G. Zein, C. Liu, S. A. A. Comhair, M. A. Aldred et al. "Mitochondrial DNA Variation and Severe Asthma". In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2961.
Testo completoMelamud, M. M., E. A. Ermakov, P. I. Brit, E. S. Zhuravlev, E. A. Balakhonova, G. A. Stepanov, D. A. Kamaeva, S. A. Ivanova, G. A. Nevinsky e V. N. Buneva. "ASSOCIATION BETWEEN HIGH CONCENTRATIONS OF CIRCULATING CELL-FREE DNA AND SUICIDE ATTEMPTS IN SCHIZOPHRENIA". In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-347.
Testo completoWan, Emily S., Michael H. Cho, Nadia Boutaoui, Barbara J. Klanderman, Jody S. Sylvia, John P. Ziniti, Augusto A. Litonjua et al. "Mitochondrial DNA Polymorphisms Are Associated With COPD". In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2921.
Testo completoAggarwal, S., I. Ahmad, S. Gu, H. Paiste, M. N. Gillespie e S. Matalon. "Mitochondrial DNA Repair Ameliorates Inhalation Lung Injury". In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1020.
Testo completovan den Heuvel, Robert. "Mitochondrial DNA levels predict COVID-19 severity". In ATS 2023 International Conference, a cura di Rachel Giles. Baarn, the Netherlands: Medicom Medical Publishers, 2023. http://dx.doi.org/10.55788/e3a1fb1a.
Testo completoCristea, Paul Dan, e Rodica Tuduce. "Nucleotide Genomic Signal analysis of hominidae mitochondrial DNA". In 2009 16th International Conference on Digital Signal Processing (DSP). IEEE, 2009. http://dx.doi.org/10.1109/icdsp.2009.5201251.
Testo completoKulvinder Singh Mann e Navjot Kaur. "Mitochondrial DNA for Bio-molecular Archaeology of mummies". In 2015 IEEE International Conference on Electrical, Computer and Communication Technologies (ICECCT). IEEE, 2015. http://dx.doi.org/10.1109/icecct.2015.7226105.
Testo completoRapporti di organizzazioni sul tema "Mitochondrial DNA"
Friddle, R. W., J. E. Klare, A. Noy, M. Corzett, R. Balhorn, R. J. Baskin, S. S. Martin e E. P. Baldwin. DNA Compaction by Yeast Mitochondrial Protein ABF2p. Office of Scientific and Technical Information (OSTI), maggio 2003. http://dx.doi.org/10.2172/15007313.
Testo completoMathews, Christopher K. DNA Precursor Metabolism and Mitochondrial Genome Stability. Fort Belvoir, VA: Defense Technical Information Center, aprile 2003. http://dx.doi.org/10.21236/ada460347.
Testo completoSAlly A. Mackenzie. Proteomic Dissection of the Mitochondrial DNA Metabolism Apparatus in Arabidopsis. Office of Scientific and Technical Information (OSTI), gennaio 2004. http://dx.doi.org/10.2172/835670.
Testo completoHsieh, Jer-Tsong. Suppression of BRCA2 by Mutant Mitochondrial DNA in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, febbraio 2012. http://dx.doi.org/10.21236/ada564267.
Testo completoHsieh, Jer-Tsong. Suppression of BRCA2 by Mutant Mitochondrial DNA in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, maggio 2013. http://dx.doi.org/10.21236/ada585765.
Testo completoHsieh, Jer-Tsong. Suppression of BRCA2 by Mutant Mitochondrial DNA in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, maggio 2011. http://dx.doi.org/10.21236/ada549344.
Testo completoIzhar, Shamay, e Maureen Hanson. Expression of Mitochondrial DNA Associated with Cytoplasmic Male Sterility in Petunia. United States Department of Agriculture, luglio 1987. http://dx.doi.org/10.32747/1987.7566866.bard.
Testo completoIzhar, Shamay, Maureen Hanson e Nurit Firon. Expression of the Mitochondrial Locus Associated with Cytoplasmic Male Sterility in Petunia. United States Department of Agriculture, febbraio 1996. http://dx.doi.org/10.32747/1996.7604933.bard.
Testo completoStevens, Tracy. Analysis of mitochondrial DNA restriction fragment patterns in killer whales, Orcinus orca. Portland State University Library, gennaio 2000. http://dx.doi.org/10.15760/etd.5812.
Testo completoHaddad, Bassem R. Detection of Mitochondrial DNA Mutations in Mammary Epithelial Cells in Nipple Aspirate Fluid. Fort Belvoir, VA: Defense Technical Information Center, settembre 2004. http://dx.doi.org/10.21236/ada434094.
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