Articoli di riviste: "Middle aged persons"

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Cho, Hae-Wol, e Chaeshin Chu. "Depression among Middle-aged Persons". Osong Public Health and Research Perspectives 8, n. 2 (30 aprile 2017): 105–7. http://dx.doi.org/10.24171/j.phrp.2017.8.2.01.

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Levkoff, Sue E., Paul D. Cleary e Terrie Wetle. "Differences in Determinants of Physician Use Between Aged and Middle-Aged Persons". Medical Care 25, n. 12 (dicembre 1987): 1148–60. http://dx.doi.org/10.1097/00005650-198712000-00004.

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Conrad Glass, Diana K. Flynn, J. "RETIREMENT NEEDS AND PREPARATION OF RURAL MIDDLE-AGED PERSONS". Educational Gerontology 26, n. 2 (marzo 2000): 109–34. http://dx.doi.org/10.1080/036012700267286.

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Hahn, Yoon Book, You Ja Ro, Num Cho Kim e Hee Seung Kim. "Quality of life of Middle-Aged Persons Who have cancer". Journal of Nurses Academic Society 20, n. 3 (1990): 399. http://dx.doi.org/10.4040/jnas.1990.20.3.399.

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Foxall, Martha J., Jeanette Y. Ekberg, Nancy Griffith e Barbara Allen Davis. "Adjustment Patterns of Chronically Ill Middle-Aged Persons and Spouses". Western Journal of Nursing Research 7, n. 4 (novembre 1985): 425–44. http://dx.doi.org/10.1177/019394598500700403.

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Wong, Tien Yin, Ronald Klein, A. Richey Sharrett, F. Javier Nieto, Lori L. Boland, David J. Couper, Thomas H. Mosley, Barbara E. K. Klein, Larry D. Hubbard e Moyses Szklo. "Retinal Microvascular Abnormalities and Cognitive Impairment in Middle-Aged Persons". Stroke 33, n. 6 (giugno 2002): 1487–92. http://dx.doi.org/10.1161/01.str.0000016789.56668.43.

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Marshall, Robert C., Claudia A. Morelli, Gina E. Calise e David S. Phillips. "Retrieval of Famous Names on a Rebus Riddle Task by Middle-Aged and Older Subjects". Perceptual and Motor Skills 85, n. 3_suppl (dicembre 1997): 1492–94. http://dx.doi.org/10.2466/pms.1997.85.3f.1492.

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This study compared the performances of 20 middle-aged and 20 older subjects on a Rebus Riddle task that required they retrieve the names of famous persons. Older subjects solved significantly more riddles and responded to prompts designed to aid riddle-solving efforts with significantly greater success than middle-aged subjects. Older subjects also had nonsignificantly faster riddle-solving times than middle-aged subjects. Similar riddles were difficult or easy for both groups. Superior performance of the older group appeared to be related to the age of the subject at the time the persons in the riddles had become famous.

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Barlow, Mary Margaret. "The Adult Development of Middle-Aged Congenitally Blind Men". Journal of Visual Impairment & Blindness 80, n. 6 (giugno 1986): 810–12. http://dx.doi.org/10.1177/0145482x8608000609.

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A special forum for individuals to respond in detail to material published in the Journal of Visual Impairment & Blindness or to raise issues which relate to the specialized field of work with blind and visually handicapped persons. Contributions should be 350–1000 words in length.

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Davis, Tara M., James Jerger e Jeffrey Martin. "Electrophysiological Evidence of Augmented Interaural Asymmetry in Middle-Aged Listeners". Journal of the American Academy of Audiology 24, n. 03 (marzo 2013): 159–73. http://dx.doi.org/10.3766/jaaa.24.3.3.

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Background: Various dimensions of auditory processing, especially the perception of speech in the presence of background competition, have been shown to deteriorate with age. A persistent problem in the assessment of these age-related changes has been the high prevalence of age-related high-frequency hearing loss in elderly persons. Some investigators have suggested that a more fruitful approach to the study of age-related decline might be to study middle-aged, rather than elderly, persons, where confounding high-frequency hearing loss is less prevalent. Purpose: To determine whether an increase in the left-ear disadvantage (LED) in dichotic listening could be demonstrated in a group of middle-aged persons. Research Design: The N400 component of the auditory event-related potential (AERP) was utilized to evaluate interaural asymmetry in a quasi-dichotic competing speech task. Electrophysiological responses were obtained on a word-pair semantic categorization task presented through a front loudspeaker while the listener ignored competing speech presented through either left (competition left [CL]) or right (competition right [CR]) loudspeakers. Study Samples: Twenty young (18–24 yr) and 20 middle-aged (44–57 yr) females with normal hearing sensitivity. Data Collection and Analysis: Individual, as well as grand-averaged, AERP waveforms and scalp topographies were analyzed for the word pairs. Peak amplitude and latency measures of the N400 component were subjected to a mixed design analysis of variance (ANOVA). Results: No significant interaural asymmetry was found in the AERP waveform for the reference word condition in either age group. In response to the second word of the pair, however, middle-aged females showed significantly greater N400 negativity in the CR condition than in the CL condition. No significant laterality effect was found in the young females. Conclusions: The study of young versus middle-aged participants may be an effective way of avoiding the confound of high-frequency hearing loss in elderly persons when studying age effects on auditory processing.

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Emick, Michelle A., e Bert Hayslip. "Custodial Grandparenting: New Roles for Middle-Aged and Older Adults". International Journal of Aging and Human Development 43, n. 2 (1 gennaio 1996): 135–54. http://dx.doi.org/10.2190/44v5-3wy2-8tck-52nq.

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An overview of grandparenting in light of changing demographics, family composition, and intergenerational dynamics is presented, as well as a review of custodial grandparenting which is impacted not only by these changes, but also by factors unique to this role. Research to date suggests that the demands of custodial grandparenting may be harmful to the psychosocial adjustment of those raising grandchildren and that such persons may be particularly in need of mental health services, especially if they are caring for problem grandchildren. However, such work also suggests that there are nevertheless many strengths and rewards associated with raising a grandchild later in life. The implications of these stressful demands on middle-aged and older persons' adjustment and life satisfaction are discussed, as are methodological issues in such research as well as future directions work in this area might take.

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Permiakova, Margarita E., e Olga S. Vindeker. "The Relationship between Happiness and “Deadly Sins” among Middle-Aged Persons". Psychology in Russia: State of the Art 14, n. 3 (2021): 244–60. http://dx.doi.org/10.11621/pir.2021.0315.

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Background. The contradictory results of studies on the relationship of happiness and well-being to norm-prohibitions make further work on this subject urgent. This topic is of particular relevance in connection with the current crisis of the value system. Objective. Our research was devoted to the study of happiness, life satisfaction, and compliance with norm-prohibitions in middle-aged Russians. We hypothesized that happiness is associated not only with life satisfaction but also with the ability to resist temptations (such as what are known as “mortal sins”). The survey used six temptations: wrath, greed, envy, sloth, gluttony, and extra pride. Resistance to these “sins” represented adherence to “norm-prohibitions”. Design. The study involved 1,520 respondents (222 male and 1,298 female). The mean age of the participants was 40.37 ± 6.01 years. The socio-demographic questionnaire included items related to gender, age, marital status, number of children, level of education, and financial situation. Happiness, life satisfaction, and adherence to “norm-prohibitions” were measured on a 10-point scale. Results. Happiness was associated with marital status, the number of children, and income per family member. It also correlated with life satisfaction, mostly in the area of relationships. Both men and women felt equally happy. The happiest people were less likely to manifest the “deadly sins” of wrath, greed, envy, and sloth. At the same time, happiness, calmness, and optimism were positively associated with pronounced gluttony and extra pride. Conclusion. The results indicate that a significant contribution to happiness is made by the ability of a person to adhere to norm-prohibitions.

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M??DER, URS, BRIAN W. MARTIN, YVES SCHUTZ e BERNARD MARTI. "Validity of Four Short Physical Activity Questionnaires in Middle-Aged Persons". Medicine & Science in Sports & Exercise 38, n. 7 (luglio 2006): 1255–66. http://dx.doi.org/10.1249/01.mss.0000227310.18902.28.

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Zisook, Sidney, Lori Montross, John Kasckow, Somaia Mohamed, Barton W. Palmer, Thomas L. Patterson, Shahrokh Golshan, Ian Fellows, David Lehman e Ellen Solorzano. "Subsyndromal Depressive Symptoms in Middle-Aged and Older Persons with Schizophrenia". American Journal of Geriatric Psychiatry 15, n. 12 (dicembre 2007): 1005–14. http://dx.doi.org/10.1097/jgp.0b013e3180a725ec.

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McKibbin, Christine L., Elizabeth Twamley, Thomas L. Patterson, Sharokh Golshan, Barry Lebowitz, Lauren Feiner, Sally Shepherd e Dilip V. Jeste. "Perceived Participation Restriction in Middle-Aged and Older Persons with Schizophrenia". American Journal of Geriatric Psychiatry 16, n. 9 (settembre 2008): 777–80. http://dx.doi.org/10.1097/jgp.0b013e318167a7cf.

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Lasoski, M. C., e M. H. Thelen. "Attitudes of Older and Middle-Aged Persons Toward Mental Health Intervention". Gerontologist 27, n. 3 (1 giugno 1987): 288–92. http://dx.doi.org/10.1093/geront/27.3.288.

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Černiauskienė, Liucija, Dalia Lukšienė, Abdonas Tamošiūnas, Regina Rėklaitienė e Lilija Margevičienė. "Association of metabolic syndrome and oxidative stress with ischemic heart disease in middle-aged persons". Medicina 44, n. 5 (10 marzo 2008): 392. http://dx.doi.org/10.3390/medicina44050051.

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The aim of this study was to evaluate the association of metabolic syndrome and oxidative stress with ischemic heart disease in middle-aged persons (men and women aged 45–64 years). Material and methods. In this study, we have used data of 533 persons (247 men and 286 women) aged 45– 64 years from Kaunas population cohort investigated according to WHO MONICA study protocol during 2001–2002 in whom concentrations of malondialdehyde, a marker of lipid peroxidation, and antioxidant vitamin E in blood serum were determined. Metabolic syndrome was defined by the criteria of Adult Treatment Panel III. Oxidative stress was determined in the presence of increased level of malondialdehyde (≥5 mmol/L) and decreased level of lipid-standardized vitamin E (<20 mmol/L). The levels of malondialdehyde and vitamin E were measured by fluorimetric methods. Results. Ischemic heart disease was diagnosed in 19.8% of men and 21.3% of women. The frequency of ischemic heart disease among persons (men and women) with metabolic syndrome was significantly higher than among persons without metabolic syndrome (27.4% vs. 17.8%, respectively; odds ratio, 1.63; P=0.032). The frequency of ischemic heart disease among persons with oxidative stress was significantly higher than among persons without oxidative stress (29.1% vs. 17.6%, respectively; odds ratio, 1.88; P=0.029). The highest prevalence of ischemic heart disease (30.0%) was among persons with metabolic syndrome and oxidative stress, and the lowest prevalence of this disease (13.8%) was among persons without metabolic syndrome and without oxidative stress (odds ratio, 2.54; P=0.017). These data were adjusted by sex and age. Conclusion. Metabolic syndrome and oxidative stress are significantly associated with ischemic heart disease among 45–64-year-old persons.

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Samusenko, A. G., e N. S. Zapariy. "RETROSPECTIVE ANALYSIS OF PRIMARY DISABILITY FOR PERSONS OF A WORKING AGE DUE TO THE NERVOUS SYSTEM DISEASES DURING THE 2014–2018 PERIOD IN MOSCOW". Здоровье населения и среда обитания - ЗНиСО 315, n. 6 (315) (25 giugno 2019): 7–10. http://dx.doi.org/10.35627/2219-5238/2019-315-6-7-10.

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We found a decrease in the number of first-recognized persons with disabilities due to the nervous system diseases among people of working age in both Moscow and the Central Federal District in the Russian Federation in the study of primary disability due to the nervous system diseases among people of working age in Moscow during the 2012–2018 period. Young people with disabilities prevailed in Moscow, middle-aged people with disabilities dominated in the Russian Federation in the first-recognized persons with disabilities structure due to the nervous system diseases among people of working age. The proportion of young people with disabilities in the first-recognized persons with disabilities structure in Moscow is higher than in the Central Federal district and the Russian Federation, and the proportion of the average age ones is lower. The level of primary disability among young people in Moscow is lower than in the Central Federal district and the Russian Federation. There is a predominance of disabled persons of group III among young people and groups I and II among middle-aged people in the first-recognized persons with disabilities structure. The level of primary disability of groups I, II and III due to the nervous system diseases is higher among middle-aged people.

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Taranina, Olga Nikolaevna, Marina Vladislavovna Silutina, Svetlana Georgievna Testova e Anna Alexandrovna Alyokhina. "THE LEVEL OF PHYSICAL ACTIVITY IN MIDDLE-AGED AND ELDERLY PEOPLE". National Association of Scientists 3, n. 31(58) (14 settembre 2020): 16–18. http://dx.doi.org/10.31618/nas.2413-5291.2020.3.58.282.

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Casabona, Antonino, Maria Stella Valle, Giulia Rita Agata Mangano e Matteo Cioni. "Identifying the Effects of Age and Speed on Whole-Body Gait Symmetry by Using a Single Wearable Sensor". Sensors 22, n. 13 (2 luglio 2022): 5001. http://dx.doi.org/10.3390/s22135001.

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Studies on gait symmetry in healthy population have mainly been focused on small range of age categories, neglecting Teenagers (13–18 years old) and Middle-Aged persons (51–60 years old). Moreover, age-related effects on gait symmetry were found only when the symmetry evaluation was based on whole-body acceleration than on spatiotemporal parameters of the gait cycle. Here, we provide a more comprehensive analysis of this issue, using a Symmetry Index (SI) based on whole-body acceleration recorded on individuals aged 6 to 84 years old. Participants wore a single inertial sensor placed on the lower back and walked for 10 m at comfortable, slow and fast speeds. The SI was computed using the coefficient of correlation of whole-body acceleration measured at right and left gait cycles. Young Adults (19–35 years old) and Adults (36–50 years old) showed stable SI over the three speed conditions, while Children (6–12 years old), Teenagers (13–18 years old), Middle-Aged persons and Elderly (61–70 and 71–84 years old) exhibited lower SI values when walking at fast speed. Overall, this study confirms that whole-body gait symmetry is lower in Children and in Elderly persons over 60 years of age, showing, for the first time, that asymmetries appear also during teenage period and in Middle-Aged persons (51–60 years old).

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Li, Lun, Andrew Wister e Barbara Mitchell. "A Study of Social Isolation, Multimorbidity and Multiple Role Demands among Middle-age Adults Based on the CLSA". Innovation in Aging 5, Supplement_1 (1 dicembre 2021): 595–96. http://dx.doi.org/10.1093/geroni/igab046.2287.

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Abstract Our understanding of the influence of concurrent multiple social and family roles on social isolation among the middle-aged generation remains limited. Given the increasing complexity of parenting, caregiving and working patterns over recent decades in many countries, and greater concern of multimorbidity in mid-life, this study examines the longitudinal effects of these contexts on social isolation among middle-aged persons. We apply Linear Mixed Models to analyze a sub-sample of 29,847 middle-aged (aged 45 to 64) participants drawn from the Baseline and Follow-up 1 waves of the Canadian Longitudinal Study on Aging. Separated analyses were conducted for participants with or without multimorbidity in order to identify patterns across these groups. Both middle-aged participants with and without multimorbidity experienced greater social isolation over time. Among participants without multimorbidity, holding multiple roles serves as a protective function to prevent social isolation over time. Among participants with multimorbidity, the parenting role remain as a protective factor; however, the caregiving role increases the risk of social isolation over time. This study confirms several life-course transitions from middle age to older age, including increased risk of social isolation and caregiving demand, and decreased parenting and working involvement. Different associations were uncovered among middle-aged persons occupying multiple roles on social isolation with and without multimorbidity over time. The findings emphasize the necessity to study multimorbidity as a salient contextual factor, and to provide enhanced support to multimorbid middle-aged individuals with increasing family caregiving demands.

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Dongug Kang. "Longitudinal Effects of a Disease/Disability on the Middle-aged & Advanced-aged Persons' Economic Status". Disability & Employment 20, n. 4 (novembre 2010): 207–35. http://dx.doi.org/10.15707/disem.2010.20.4.009.

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Wojciechowska, Ludwika. "Basic Hope And Generativity In Middle Adulthood". Polish Psychological Bulletin 42, n. 4 (1 gennaio 2011): 188–97. http://dx.doi.org/10.2478/v10059-011-0025-7.

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Basic Hope And Generativity In Middle Adulthood The aim of the presented research was to investigate the relationship between the level of basic hope and the level and type of generativity in persons in middle adulthood. Hypotheses were posited and a positive correlation relationship was expected between basic hope and generativity, as well as a stronger relationship between those variables in the group of women than in the group of men, as well as a stronger relationship in the group of persons with a higher level of education than in the group of persons with a lower level of education. A sample of 120 persons was studied, of which 70 were women and 50 constituted men aged between 40-65 years. Two measurement instruments were used - one to diagnose generativity (author's own instrument), and the second to measure basic hope devised by Trzebiński and Zięba. The results of the conducted research have confirmed the posited hypotheses.

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Pepelyaev, E. G., V. A. Semenov e O. A. Gromova. "BDNF level role in formation of cognitive violations at middle-aged persons". Pharmacokinetics and Pharmacodynamics, n. 2 (1 dicembre 2020): 37–41. http://dx.doi.org/10.37489/2587-7836-2020-2-37-41.

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WATANABE, Junichi, e Koichiro OKA. "Effectiveness of press needle among middle-aged persons with chronic knee pain". Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion) 66, n. 2 (2016): 80–89. http://dx.doi.org/10.3777/jjsam.66.80.

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Grimm, Wolfram, Julia Liedtke e Hans-Helge Muller. "Prevalence of Potential Noninvasive Arrhythmia Risk Predictors in Healthy, Middle-Aged Persons". Annals of Noninvasive Electrocardiology 8, n. 1 (gennaio 2003): 37–46. http://dx.doi.org/10.1046/j.1542-474x.2003.08107.x.

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Evans, Anthony J., Martin Juneau, Martin Yee, William L. Haskell, C. Barr Taylor e Robert F. DeBusk. "TRAINING-INDUCED DECREASE IN AVERAGE DAILY HEART RATE IN MIDDLE-AGED PERSONS". Medicine & Science in Sports & Exercise 18, supplement (aprile 1986): S54. http://dx.doi.org/10.1249/00005768-198604001-00267.

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Folsom, David P., Christine McKibbin, Dilip V. Jeste e Thomas Patterson. "Use of primary care by middle aged and older persons with schizophrenia". Primary Care and Community Psychiatry 11, n. 3 (1 febbraio 2007): 101–6. http://dx.doi.org/10.1185/135525706x121174.

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Englund, Martin, Ali Guermazi, Daniel Gale, David J. Hunter, Piran Aliabadi, Margaret Clancy e David T. Felson. "Incidental Meniscal Findings on Knee MRI in Middle-Aged and Elderly Persons". New England Journal of Medicine 359, n. 11 (11 settembre 2008): 1108–15. http://dx.doi.org/10.1056/nejmoa0800777.

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Sasaki, Hideo, Fumiyoshi Kasagi, Michiko Yamada e Shoichiro Fujita. "Grip Strength Predicts Cause-Specific Mortality in Middle-Aged and Elderly Persons". American Journal of Medicine 120, n. 4 (aprile 2007): 337–42. http://dx.doi.org/10.1016/j.amjmed.2006.04.018.

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KVAPIL, MILAN, PAVEL ŠTOLBA, DAN WICHTERLE e PAVEL DVOŘÁK. "Insulin Resistance and Compensatory Insulin Secretion in Middle-Aged Persons with Hypertriglyceridemia". Annals of the New York Academy of Sciences 683, n. 1 Dietary Lipid (giugno 1993): 295–301. http://dx.doi.org/10.1111/j.1749-6632.1993.tb35720.x.

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Johs, Nikolas A., Kunling Wu, Katherine Tassiopoulos, Susan L. Koletar, Robert C. Kalayjian, Ronald J. Ellis, Babafemi Taiwo, Frank J. Palella e Kristine M. Erlandson. "Disability Among Middle-Aged and Older Persons With Human Immunodeficiency Virus Infection". Clinical Infectious Diseases 65, n. 1 (27 marzo 2017): 83–91. http://dx.doi.org/10.1093/cid/cix253.

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Cutler, Stephen J., e Lynne G. Hodgson. "Correlates of personal concerns about developing Alzheimer's disease among middle-aged persons". American Journal of Alzheimer's Disease & Other Dementiasr 16, n. 6 (novembre 2001): 335–43. http://dx.doi.org/10.1177/153331750101600604.

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VYAS, M., J. IZZOJR, Y. LACOURCIERE, J. ARNOLD, M. DUNLAP, M. PFEFFER e G. MITCHELL. "Augmentation index and central aortic stiffness in middle-aged and older persons". American Journal of Hypertension 18, n. 5 (maggio 2005): A23. http://dx.doi.org/10.1016/j.amjhyper.2005.03.059.

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Bressler, Neil M. "Retinal Arteriolar Narrowing and Risk of Diabetes Mellitus in Middle-aged Persons". Archives of Ophthalmology 121, n. 1 (1 gennaio 2003): 113. http://dx.doi.org/10.1001/archopht.121.1.113.

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Story Jovanova, Olivera, Ivana Nedeljkovic, Derek Spieler, Rosie M. Walker, Chunyu Liu, Michelle Luciano, Jan Bressler et al. "DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons". JAMA Psychiatry 75, n. 9 (1 settembre 2018): 949. http://dx.doi.org/10.1001/jamapsychiatry.2018.1725.

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Wong, Tien Yin. "Retinal Arteriolar Narrowing and Risk of Diabetes Mellitus in Middle-aged Persons". JAMA 287, n. 19 (15 maggio 2002): 2528. http://dx.doi.org/10.1001/jama.287.19.2528.

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González-González, Ana Isabel, Robin Brünn, Julia Nothacker, Christine Schwarz, Edris Nury, Truc Sophia Dinh, Maria-Sophie Brueckle, Mirjam Dieckelmann, Beate Sigrid Müller e Marjan van den Akker. "Everyday Lives of Middle-Aged Persons with Multimorbidity: A Mixed Methods Systematic Review". International Journal of Environmental Research and Public Health 19, n. 1 (21 dicembre 2021): 6. http://dx.doi.org/10.3390/ijerph19010006.

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The healthcare burden of patients with multimorbidity may negatively affect their family lives, leisure time and professional activities. This mixed methods systematic review synthesizes studies to assess how multimorbidity affects the everyday lives of middle-aged persons, and identifies skills and resources that may help them overcome that burden. Two independent reviewers screened title/abstracts/full texts in seven databases, extracted data and used the Mixed Methods Appraisal Tool (MMAT) to assess risk of bias (RoB). We synthesized findings from 44 studies (49,519 patients) narratively and, where possible, quantitatively. Over half the studies provided insufficient information to assess representativeness or response bias. Two studies assessed global functioning, 15 examined physical functioning, 18 psychosocial functioning and 28 work functioning. Nineteen studies explored skills and resources that help people cope with multimorbidity. Middle-aged persons with multimorbidity have greater impairment in global, physical and psychosocial functioning, as well as lower employment rates and work productivity, than those without. Certain skills and resources help them cope with their everyday lives. To provide holistic and dynamic health care plans that meet the needs of middle-aged persons, health professionals need greater understanding of the experience of coping with multimorbidity and the associated healthcare burden.

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Serpa, Jose A., Josemon Valayam, Daniel M. Musher, Roger D. Rossen, Liise-anne Pirofski e Maria C. Rodriguez-Barradas. "VH3 Antibody Response to Immunization with Pneumococcal Polysaccharide Vaccine in Middle-Aged and Elderly Persons". Clinical and Vaccine Immunology 18, n. 3 (12 gennaio 2011): 362–66. http://dx.doi.org/10.1128/cvi.00408-10.

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ABSTRACTPneumococcal disease continues to cause substantial morbidity and mortality among the elderly. Older adults may have high levels of anticapsular antibody after vaccination, but their antibodies show decreased functional activity. In addition, the protective effect of the pneumococcal polysaccharide vaccine (PPV) seems to cease as early as 3 to 5 years postvaccination. Recently, it was suggested that PPV elicits human antibodies that use predominantly VH3 gene segments and induce a repertoire shift with increased VH3 expression in peripheral B cells. Here we compared VH3-idiotypic antibody responses in middle-aged and elderly subjects receiving PPV as initial immunization or revaccination. We studied pre- and postvaccination sera from 36 (18 vaccine-naïve and 18 previously immunized subjects) middle-aged and 40 (22 vaccine-naïve and 18 previously immunized subjects) elderly adults who received 23-valent PPV. Concentrations of IgGs to four individual serotypes (6B, 14, 19F, and 23F) and of VH3-idiotypic antibodies (detected by the monoclonal antibody D12) to the whole pneumococcal vaccine were determined by enzyme-linked immunosorbent assay (ELISA). PPV elicited significant IgG and VH3-idiotypic antibody responses in middle-aged and elderly subjects, regardless of whether they were vaccine naïve or undergoing revaccination. Age did not influence the magnitude of the antibody responses, as evidenced by similar postvaccination IgG and VH3 antibody levels in both groups, even after stratifying by prior vaccine status. Furthermore, we found similar proportions (around 50%) of elderly and middle-aged subjects experiencing 2-fold increases in VH3 antibody titers after vaccination. Age or repeated immunization does not appear to affect the VH3-idiotypic immunogenicity of PPV among middle-aged and elderly adults.

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Hayashi, Masaki, Masahiro Takeshima, Tomoko Hosoya e Yu Kume. "24-Hour Rest-Activity Rhythm in Middle-Aged and Older Persons with Depression". International Journal of Environmental Research and Public Health 20, n. 7 (27 marzo 2023): 5275. http://dx.doi.org/10.3390/ijerph20075275.

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Changes in rest or active states were clinically observed in persons with depression. However, the association between symptoms of depression and 24 h rest-activity rhythm (RAR) components that can be measured using wearable devices was not clarified. This preliminary cross-sectional study aimed to clarify the 24 h RAR components associated with symptoms of depression in middle-aged and older persons. Participants were recruited from among inpatients and outpatients requiring medical treatment at Akita University Hospital for the group with depression and from among healthy volunteers living in Akita prefecture, Japan, for the healthy control group. To assess RAR parameters including inter-daily stability (IS), intra-daily variability (IV), relative amplitude (RA), and average physical activity level for the most active 10 h span (M10) or for the least active 5 h span (L5), all the participants were instructed to wear an Actiwatch Spectrum Plus device on their non-dominant wrist for seven days. Twenty-nine persons with depression and 30 controls were included in the analysis. The results of a binomial regression analysis showed that symptoms of depression were significantly associated with a high IS value (odds ratio [OR], 1.20; 95% confidence interval [95% CI], 1.01–1.44; p = 0.04) and a low M10 value (OR, 0.85; 95% CI, 0.74–0.96; p = 0.01). Our findings suggest potential components of 24 h RAR are associated with depression.

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Pasko, Viktoriia. "Indicators of plasma hemostasis in hypertensive patients of different age groups". issue 2 2024, n. 2 2024 (3 giugno 2024): 91–96. http://dx.doi.org/10.47855/jal9020-2024-5-12.

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Background. Scientific works of several authors determine age-related differences in hemocoagulation hemostasis. Thus, in older people, changes in hemovascular hemostasis are noted with impaired vasomotor, anticoagulant and fibrinolytic activity of the endothelium. Anticoagulant system disorders increase with age. There are few studies on plasma hemostasis in arterial hypertension patients, especially in older age groups. Aim: The study aimed at a complex research and comparative assessment of the plasma state hemostasis parameters in older and middle-aged hypertensive patients. Materials and methods. 134 patients who were divided into 2 groups were examined. Group I (n = 65) – the older hypertensive patients (60 - 74 years); group II (n = 69) – the middle-aged hypertensive patients (45 - 59 years) respectively. 15 people were involved in the control for each of the studied groups (group III – the older persons and group IV – the middle-aged persons) comparable to the main in terms of age and sex. They were divided into 2 groups of 24-hour day profile of blood pressure: dippers and non-dippers. Fibrinogen (g/l) was determined on an Amelung KC 1A hemocoagulometer to assess the plasma hemostasis state. The fibrinolytic activity of plasma (min) was according to the Kowalski method, antithrombin III (%) with the help of Humalyzer Junior filter photometer. Results. When comparing the plasma hemostasis indicators in the older and the middle-aged patients the value of antithrombin III in the middle-aged persons exceeded the similar indicator in the older persons. That is, in older patients, on the contrary, suppression of fibrinolytic and anticoagulant activity is noted. A significant slowing of the indicator of fibrinolysis activity was found in the middle-aged patients of the dipper group compared to the control group. A significant decrease in the fibrinogen level was found in the older patients in the dipper group and its increase in the non-dipper group relative to the control. The level of the antithrombin III significantly decreased in the non-dipper group compared to normative indicators. Conclusions. 1. The significant decrease in anticoagulant activity against the background of suppressed fibrinolysis according to indicators of the plasma hemostasis of the older patients was noted. 2. The thrombogenicity of blood plasma revealed by us during the study of plasma hemostasis indicates the high probability of thrombotic complications developing in patients. _________________________________________________________________________________________ Keywords: arterial hypertension; essential hypertension; plasma hemostasis; fibrinogen; fibrinolytic activity of plasma; antithrombin III

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Lee, Hyunkee. "The Longitudinal Relationships between Volunteering and Cognitive Function of Middle and Aged People in Korea". Korea Gerontological Society 43, n. 6 (1 dicembre 2023): 989–1007. http://dx.doi.org/10.31888/jkgs.2023.43.6.989.

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This study investigates the longitudinal associations between volunteering among older adults and the cognitive functioning for the purpose of preventing the cognitive decline, examining how volunteerism of older persons affects the cognitive functioning. For the purpose, the study analyzes about 8,688 older subjects who are observed six times with intervals of two years, using statistical analysis model of linear multilevel mixed regression. The results show that volunteering is associated with higher level of cognitive function over time, and the education moderates the association, with volunteering benefiting the most differentially least-educated elderly among four higher-educated groups. Also age weakens the effect size of volunteering, but volunteering effects work in all ages. Volunteering is lifestyle behaviors that enhance cognitive functioning of older persons. The results suggests that cognition-strengthened volunteer programs are beneficial to older persons at the population level.

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Bond, John B., Marcel R. Baril, Sara Axelrod e Lynn Crawford. "Support To Older Parents By Middle-Aged Children". Canadian Journal of Community Mental Health 9, n. 1 (1 aprile 1990): 163–78. http://dx.doi.org/10.7870/cjcmh-1990-0012.

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This survey examined aspects of the support provided by 388 middle-aged respondents to their parents and parents-in-law independently residing in the same city. Burden was found to be relatively low (mean = 8.19 on a 33-point scale), and generally not associated with demographic characteristics of the care provider (sex, age, marital status, number of children, employment status, income, etc.). Higher burden was associated with provision of more support and lower emotional closeness to the parent. More help was provided to women and persons with higher dependency needs. When comparing the most and least burdened caregivers, frail and deteriorating health of the parent seemed to be the critical factor. The relationship between parent and most burdened children was neither as satisfying nor as open as for the least burdened children. Parents of those who were most burdened already were in receipt of more formal services than the parents of the least burdened. Given the relatively low burden reported by the middle-aged offspring, formal programs were not instituted by the social-service agency. However, agencies responsible for providing formal care to the elderly might query the nature of the relationships between their clients and offspring, seeking particular sources of stress and burden which might be alleviated.

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Bond, John B., Carol D. H. Harvey e Elizabeth A. Hildebrand. "Familial Support of the Elderly in a Rural Mennonite Community". Canadian Journal on Aging / La Revue canadienne du vieillissement 6, n. 1 (1987): 7–17. http://dx.doi.org/10.1017/s071498080001535x.

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AbstractWith an increasing number of persons entering old age and having longer life expectancies, there has been a consequent alteration of family dynamics, such that middle aged individuals frequently provide support to their older parents. At the same time, the middle aged person is often in the midst of raising his or her own children, attending to personal aspirations, and enacting the role of spouse.This study investigated support from middle aged offspring to elderly parents in a rural Mennonite community. Information on the expectation for and consequences of support to parents was gathered from pastors and middle aged family members in two Mennonite conferences, as well as from a Lutheran sample with a similar historical background.Pastoral interviews showed no differences in doctrinal beliefs regarding familial care of parents, although the institutional church responses varied. Middle aged offspring in the Lutheran congregation reported less involvement in religious practice than did members of either Mennonite congregation. Burden of caring for elderly parents felt by middle aged people showed no statistically significant differences between congregations; however, greater reported religiosity was associated with lesser burden.

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Gonzalez-Gonzalez, Ana Isabel, Robin Brünn, Julia Nothacker, Truc Sophia Dinh, Maria-Sophie Brueckle, Mirjam Dieckelmann, Beate S. Müller e Marjan van den Akker. "Everyday lives of middle-aged persons living with multimorbidity: protocol of a mixed-methods systematic review". BMJ Open 11, n. 12 (dicembre 2021): e050990. http://dx.doi.org/10.1136/bmjopen-2021-050990.

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IntroductionMultimorbidity is the simultaneous occurrence of several (chronic) diseases. Persons living with multimorbidity not only have complex care needs, but the burden of care often has a negative impact on their family lives, leisure time and professional activities. The aim of this project is to systematically review the literature to assess how multimorbidity affects the everyday lives of middle-aged persons, and to find out what abilities and resources help in the development of coping strategies to overcome the challenges of living with it.Methods and analysisWe will systematically search for studies reporting on the everyday life experiences of middle-aged persons (30–60 years) with multimorbidity (≥2 chronic conditions) in MEDLINE, CINAHL, PsycINFO, Social Sciences Citation Index, Social Sciences Citation Index Expanded, PSYNDEX and The Cochrane Library from inception. We will include all primary studies that use quantitative, qualitative and mixed methodologies, irrespective of publication date/study setting.Two independent reviewers will screen titles/abstracts/full texts, extract data from the selected studies and present evidence in terms of study/population characteristics, data collection method and the phenomenon of interest, that is, everyday life experiences of middle-aged persons with multimorbidity. Risk of bias will be independently assessed by two reviewers using the Mixed Methods Appraisal Tool. We will use a convergent integrated approach on qualitative/quantitative studies, whereby information will be synthesised narratively and, if possible, quantitatively.Ethics and disseminationEthical approval is not required due to the nature of the proposed systematic review. Results from this research will be disseminated at relevant (inter)national conferences and via publication in peer-reviewed journals.PROSPERO registration numberCRD42021226699.

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BUCHHEIT, MARTIN, CHANTAL SIMON, ANNE CHARLOUX, ST??PHANE DOUTRELEAU, FRAN??OIS PIQUARD e GABRIELLE BRANDENBERGER. "Heart Rate Variability and Intensity of Habitual Physical Activity in Middle-Aged Persons". Medicine & Science in Sports & Exercise 37, n. 9 (settembre 2005): 1530–34. http://dx.doi.org/10.1249/01.mss.0000177556.05081.77.

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Hershman, Jerome M., A. Eugene Pekary, Loretta Berg, David H. Solomon e Clark T. Sawin. "Serum Thyrotropin and Thyroid Hormone Levels in Elderly and Middle-Aged Euthyroid Persons". Journal of the American Geriatrics Society 41, n. 8 (agosto 1993): 823–28. http://dx.doi.org/10.1111/j.1532-5415.1993.tb06177.x.

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Nyquist, P. A., L. R. Yanek, M. Bilgel, J. L. Cuzzocreo, L. C. Becker, K. Chevalier-Davis, D. Yousem et al. "Effect of white matter lesions on manual dexterity in healthy middle-aged persons". Neurology 84, n. 19 (10 aprile 2015): 1920–26. http://dx.doi.org/10.1212/wnl.0000000000001557.

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Ross, Dennis G. "Altered Bowel Elimination Patterns among Hospitalized Elderly and Middle-Aged Persons: Quantitative Results". Orthopaedic Nursing 14, n. 1 (gennaio 1995): 25–31. http://dx.doi.org/10.1097/00006416-199501000-00006.

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González González, Ana Isabel, Truc Sophia Dinh, Robin Brünn, Maria-Sophie Brueckle, Christine Schwarz, Mirjam Dieckelmann, Beate Müller e Marjan van den Akker. "Multimorbidity in middle-aged persons: experiences of patients and their health care providers: Protocol of a qualitative stakeholder analysis". F1000Research 11 (14 giugno 2022): 655. http://dx.doi.org/10.12688/f1000research.121794.1.

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Middle-aged persons with multimorbidity have to take their illnesses into account in their daily work, family and leisure activities. The MuMiA project aims to identify early preventive measures that make it easier for those between 30 and 60 years of age with multiple chronic diseases to manage their illnesses in their everyday lives. An interdisciplinary workshop and interviews with multimorbid middle-aged adults and their principal healthcare providers will be used to collect information on the management of care in the contexts of patients’ daily work, family and leisure activities. Data obtained in the interviews will be coded inductively and analysed using content analysis. Workshop outputs will be transcribed and evaluated by the authors. This study has received ethical approval from the Faculty of Medicine Ethics Committee of Goethe University (2021-47). The project will generate prevention recommendations that reflect the experiences of middle-aged persons living with multimorbidity and the views of their principal healthcare providers. The findings will be disseminated via conferences and peer-reviewed publications.

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Shinan-Altman, Shiri, e Perla Werner. "Subjective Age and Its Correlates Among Middle-Aged and Older Adults". International Journal of Aging and Human Development 88, n. 1 (23 gennaio 2018): 3–21. http://dx.doi.org/10.1177/0091415017752941.

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The present study evaluates discrepancies in subjective age as reported by middle-age persons (aged 44–64 years) in comparison to older adults (aged 65 years and older), using a multidimensional definition of the concept. A convenience sample of 126 middle-aged and 126 older adults completed subjective age measures (felt age, desired age, and perceived old age), attitudes toward older adults, knowledge about aging, and sociodemographic questionnaires. Overall, participants reported feeling younger than they actually were and wanting to be younger than their chronological age. Perceived mean for old age was about 69 years. Discrepancies in felt age and desired age were significantly larger for the older group compared to the middle-aged group. Regarding perceived old age, compared to the younger group, older adults reported that old age begins at an older age. Findings suggest that middle-aged and older adults’ perceptions regarding themselves and regarding old age in general are independent and need, therefore, separate research and practical attention.

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