Bibliografie tematiche / Membrane proteins

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Letteratura scientifica selezionata sul tema "Membrane proteins"

Autore: Grafiati
Pubblicato: 4 giugno 2021
Ultima modifica: 2 novembre 2024

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Articoli di riviste sul tema "Membrane proteins"

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Jin, Wenzhen, e Syoji T. akada. "1P103 Asymmetry in membrane protein sequence and structure : Glycine outside rule(Membrane proteins,Oral Presentations)". Seibutsu Butsuri 47, supplement (2007): S49. http://dx.doi.org/10.2142/biophys.47.s49_2.

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Kühlbrandt, Werner. "Membrane proteins". Current Opinion in Structural Biology 1, n. 4 (agosto 1991): 531–33. http://dx.doi.org/10.1016/s0959-440x(05)80073-9.

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KUHLBRANDT, W., e E. GOUAUX. "Membrane proteins". Current Opinion in Structural Biology 9, n. 4 (agosto 1999): 445–47. http://dx.doi.org/10.1016/s0959-440x(99)80062-1.

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Hurley, James H. "Membrane Proteins". Chemistry & Biology 10, n. 1 (gennaio 2003): 2–3. http://dx.doi.org/10.1016/s1074-5521(03)00006-1.

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Gennis, Robert B., e Werner Kühlbrandt. "Membrane proteins". Current Opinion in Structural Biology 3, n. 4 (agosto 1993): 499–500. http://dx.doi.org/10.1016/0959-440x(93)90074-u.

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Garavito, RMichael, e Arthur Karlin. "Membrane proteins". Current Opinion in Structural Biology 5, n. 4 (agosto 1995): 489–90. http://dx.doi.org/10.1016/0959-440x(95)80033-6.

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Picard, Martin. "Membrane proteins". Biochimie 205 (febbraio 2023): 1–2. http://dx.doi.org/10.1016/j.biochi.2023.01.018.

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Ralston, GB. "Proteins of Marsupial Erythrocyte Membranes". Australian Journal of Biological Sciences 38, n. 1 (1985): 121. http://dx.doi.org/10.1071/bi9850121.

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The proteins of erythrocyte membranes from the red kangaroo, western grey kangaroo, eastern grey wallaroo (euro), red-necked wallaby, Tammar wallaby, and brush-tail possum have been fractionated on acrylamide gels in the presence of sodium dodecyl sulfate. The pattern of proteins was remarkably similar between the different marsupial species. The pattern of Coomassie blue-staining proteins in the membranes of these species was also very similar to that of the human erythrocyte membrane. However, the glycoproteins in the marsupial erythrocyte membranes were markedly less conspicuous than those of the human erythrocyte membrane. Furthermore, the mobilities of the glycoproteins from the marsupials were different from those of the human erythrocyte membrane.
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Brown, D., e G. L. Waneck. "Glycosyl-phosphatidylinositol-anchored membrane proteins." Journal of the American Society of Nephrology 3, n. 4 (ottobre 1992): 895–906. http://dx.doi.org/10.1681/asn.v34895.

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Many proteins of eukaryotic cells are anchored to membranes by covalent linkage to glycosyl-phosphatidylinositol (GPI). These proteins lack a transmembrane domain, have no cytoplasmic tail, and are, therefore, located exclusively on the extracellular side of the plasma membrane. GPI-anchored proteins form a diverse family of molecules that includes membrane-associated enzymes, adhesion molecules, activation antigens, differentiation markers, protozoan coat components, and other miscellaneous glycoproteins. In the kidney, several GPI-anchored proteins have been identified, including uromodulin (Tamm-Horsfall glycoprotein), carbonic anhydrase type IV, alkaline phosphatase, Thy-1, BP-3, aminopeptidase P, and dipeptidylpeptidase. GPI-anchored proteins can be released from membranes with specific phospholipases and can be recovered from the detergent-insoluble pellet after Triton X-114 treatment of membranes. All GPI-anchored proteins are initially synthesized with a transmembrane anchor, but after translocation across the membrane of the endoplasmic reticulum, the ecto-domain of the protein is cleaved and covalently linked to a preformed GPI anchor by a specific transamidase enzyme. Although it remains obscure why so many proteins are endowed with a GPI anchor, the presence of a GPI anchor does confer some functional characteristics to proteins: (1) it is a strong apical targeting signal in polarized epithelial cells; (2) GPI-anchored proteins do not cluster into clathrin-coated pits but instead are concentrated into specialized lipid domains in the membrane, including so-called smooth pinocytotic vesicles, or caveoli; (3) GPI-anchored proteins can act as activation antigens in the immune system; (4) when the GPI anchor is cleaved by PI-phospholipase C or PI-phospholipase D, second messengers for signal transduction may be generated; (5) the GPI anchor can modulate antigen presentation by major histocompatibility complex molecules. Finally, at least one human disease, paroxysmal nocturnal hemoglobinuria, is a result of defective GPI anchor addition to plasma membrane proteins.
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Walker, J. "Membrane proteins Membrane protein structure". Current Opinion in Structural Biology 6, n. 4 (agosto 1996): 457–59. http://dx.doi.org/10.1016/s0959-440x(96)80109-6.

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Tesi sul tema "Membrane proteins"

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Gill, Katrina Louise. "Protein-protein interactions in membrane proteins". Thesis, University of Newcastle Upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400016.

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Hedin, Linnea E., Kristoffer Illergård e Arne Elofsson. "An Introduction to Membrane Proteins". Stockholms universitet, Institutionen för biokemi och biofysik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-69241.

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Abstract (sommario):
alpha-Helical membrane proteins are important for many biological functions. Due to physicochemical constraints, the structures of membrane proteins differ from the structure of soluble proteins. Historically, membrane protein structures were assumed to be more or less two-dimensional, consisting of long, straight, membrane-spanning parallel helices packed against each other. However, during the past decade, a number of the new membrane protein structures cast doubt on this notion. Today, it is evident that the structures of many membrane proteins are equally complex as for many soluble proteins. Here, we review this development and discuss the consequences for our understanding of membrane protein biogenesis, folding, evolution, and bioinformatics.

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Kota, Jhansi. "Membrane chaperones : protein folding in the ER membrane /". Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-102-9/.

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Whitehead, L. "Computer simulation of biological membranes and membrane bound proteins". Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297412.

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Armstrong, James P. "Artificial membrane-binding proteins". Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686615.

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Membrane functionalization is a promising strategy for augmenting cell performance in regenerative medicine. To this end, the design, construction, characterisation and cell affinity of protein-polymer surfactant nanoconstructs are presented. Nanoconstructs of eGFP were synthesised that exhibited near-native structure and function, as well as effective and persistent membrane affinity. Human mesenchymal stem cells were labelled for up to ten days in culture, without affecting cell viability or differentiation capacity. This "cell priming" technology has been used to address the issue of hypoxia-related central necrosis during in-vitro tissue engineering. Specifically, nanoconstructs of myoglobin, with enhanced oxygen-binding affinity, were synthesised and used to prime mesenchymal stem cells prior to hyaline cartilage engineering. The myoglobin-primed cells produced tissue constructs with a 62 % increase in type II : type I collagen ratio and, significantly, a reduction in cell necrosis from 42 ± 24 % to 7 ± 6 %.
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Zhang, Xiao Xiao. "Identification of membrane-interacting proteins and membrane protein interactomes using Nanodiscs and proteomics". Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/39413.

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The insoluble nature of membrane proteins has complicated the identification of their interactomes. The Nanodisc has allowed the membrane and membrane proteins to exist in a soluble state. In this thesis, we combined Nanodisc and proteomics and applied the technique to discover the interactome of membrane proteins. Using the SecYEG and MalFGK membrane complex incorporated into Nanodisc, we identified, Syd, SecA, and MalE. These interactions were identified with high specificity and confidence from total soluble protein extracts. The protein YidC was also tested but no interactors were detected. Overall, these results showed that the technique can identify periplasmic and cytosolic interacting partners with high degree of specificity. In a second approach, the method was applied to detect proteins with high affinity for lipid using S. cerevisiae as a model organism. Using Nanodiscs containing different types of phospholipids, many known lipid interactors were identified, including: Ypt1, Sec4, Vps21, Osh6, and Faa1. Interestingly, Caj1 was identified as a PA specific interactor and this interaction was found to be pH dependent. Liposome sedimentation assay showed that Caj1 has affinity for acidic phospholipids. In vivo analysis confirmed the plasma membrane localization of N’-GFP-Caj1 and specifically to the yeast buds. However, pH dependent localization was not observed. Together, with the in vivo and in vitro results suggests that Caj1 is an acidic phospholipid interacting protein.
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Josyula, Ratnakar. "Structural studies of yeast mitochondrial peripheral membrane protein TIM44". Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2009p/josyula.pdf.

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Rapp, Mikaela. "The Ins and Outs of Membrane Proteins : Topology Studies of Bacterial Membrane Proteins". Doctoral thesis, Stockholm : Department of Biochemistry and Biophysics, Stockholm University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1330.

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Berger, Bryan William. "Protein-surfactant solution thermodynamics applications to integral membrane proteins /". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 15.42 Mb., 304 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3200533.

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Keegan, Neil. "From engineered membrane proteins to self-assembling protein monolayers". Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419991.

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Libri sul tema "Membrane proteins"

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Ghirlanda, Giovanna, e Alessandro Senes, a cura di. Membrane Proteins. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-583-5.

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Azzi, Angelo, Lanfranco Masotti e Arnaldo Vecli, a cura di. Membrane Proteins. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3.

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C, Goheen Steven, e Bio-Rad Laboratories, a cura di. Membrane proteins: Proceedings of the Membrane Protein Symposium. [United States]: Bio-Rad Laboratories, 1987.

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H, White Stephen, a cura di. Membrane protein structure: Experimental approaches. New York: Oxford University Press, 1994.

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Graham, J. M. Membrane analysis. Oxford, UK: BIOS Scientific Publishers, 1997.

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1940-, Hille Bertil, Fambrough Douglas M e Society of General Physiologists, a cura di. Proteins of excitable membranes. New York: Society of General Physiologists and Wiley-Interscience, 1987.

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Kleinschmidt, Jörg H. Lipid-protein Interactions: Methods and protocols. New York: Humana Press, 2013.

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J, Kenny A., e Turner A. J. 1947-, a cura di. Mammalian ectoenzymes. Amsterdam: Elsevier, 1987.

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Stefan, Bröer, e Wagner Carsten A, a cura di. Membrane transporter diseases. New York: Kluwer Academic/Plenum Publishers, 2003.

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C, Froehner Stanley, e Bennett Vann, a cura di. Cytoskeletal regulation of membrane function. New York: Rockefeller University Press, 1997.

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Capitoli di libri sul tema "Membrane proteins"

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Broger, Clemens, Reinhard Bolli e Angelo Azzi. "Spin Labeling of Membranes and Membrane Proteins". In Membrane Proteins, 136–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_15.

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Bolli, Reinhard, Clemens Broger e Angelo Azzi. "Purification of Cytochrome c Reductase and Oxidase by Affinity Chromatography". In Membrane Proteins, 3–10. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_1.

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Spisni, A., G. Farruggia e L. Franzoni. "Polypeptide-Lipid Interactions as Studied by 13C NMR". In Membrane Proteins, 86–94. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_10.

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Masotti, L., J. Von Berger e N. Gesmundo. "Conformational Changes in Polypeptides and Proteins Brought About by Interactions with Lipids". In Membrane Proteins, 95–106. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_11.

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Müller, Michele, e Angelo Azzi. "Two Examples of Selective Fluorescent Labeling of SH-Groups with Eosin-5-Maleimide: The ADP/ATP Translocator and the Cytochrome c Oxidase Subunit III of Bovine Heart Mitochondria". In Membrane Proteins, 109–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_12.

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Montecucco, C. "Hydrophobic Photolabeling with 125I-TID of Red Blood Cell Membranes". In Membrane Proteins, 119–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_13.

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Brandolin, Gérard, Marc R. Block, François Boulay e Pierre V. Vignais. "Use of Fluorescent Probes of the Adenine Nucleotide Carrier for Binding Studies and Analysis of Conformational Changes". In Membrane Proteins, 124–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_14.

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Nałȩcz, M. J., e A. Azzi. "Functional Reconstitution of the Mitochondrial Cytochrome b-c1 Complex: Effect of Cholesterol". In Membrane Proteins, 151–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_16.

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Nałȩcz, M. J., A. Szewczyk e L. Wojtczak. "Changes of the Membrane Surface Potential Measured by Amphiphilic Fluorescent and ESR Probes". In Membrane Proteins, 160–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_17.

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Capitanio, N., e S. Papa. "Reconstitution of Cytochrome c Oxidase". In Membrane Proteins, 168–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_18.

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Atti di convegni sul tema "Membrane proteins"

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Russo, Michael J., Simon H. Friedman, Jens O. M. Karlsson e Mehmet Toner. "A Two-Compartment Membrane Limited Model of Molecular Transport Through Nano-Scale Pores With a Metal-Actuated Switch". In ASME 1997 International Mechanical Engineering Congress and Exposition, 9–14. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1306.

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Abstract We have previously demonstrated that we can reversibly alter the transport selectivity of the plasma membrane to small molecules (∼1000 Da) by treating cells with H5, a genetic mutant of the pore-forming protein Staphylococcus aureus α-toxin, designed to be equipped with a metal-actuated switch. Toward the development of a plasma membrane permeabilization technique for both clinical and basic research applications, we have developed a simple model of molecular transport through the H5 pore. This model in combination with hindered transport models predicts the rate of transport of our marker molecules, carboxycalcein blue (CCB) and sucrose, and provides an approximation of the number of pores in the plasma membrane. Model predictions are also in reasonable agreement with experimental measurements of CCB and sucrose transport through the H5 treated plasma membranes of 3T3 fibroblasts. This model allows us to analyze quantitatively the selectivity of the H5 pore and by extension to use genetically designed pore forming proteins to advance the understanding of hindered transport in pores.
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Lapetina, Eduardo G., Bryan R. Reep e Luis Molina Y. Vedia. "NOVEL GTP-BINDING PROTEINS OF CYTOSOLIC AND MEMBRANE FRACTIONS OF HUMAN PLATELETS". In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644629.

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We have assessed the binding of (α-32P)GTP to platelet proteins from cytosolic and membrane fractions. Proteins were separated by SDS-PAGE and electrophoretically transferred to nitrocellulose. Incubation of the nitrocellulose blots with (α-32p)GTP indicated the presence of specific and distinct GTP-binding proteins in cytosol and membranes. Binding was prevented by 10-100 nM GTP or GTPyS and by 100 nM GDP; binding was unaffected by 1 nM-1 μM ATP. One main GTP-binding protein (29.5 KDa) was detected in the membrane fraction while three others (29, 27, and 21 KDa) were detected in the soluble fraction. Two cytosolic GTP-binding proteins (29 and 27 KDa) were degraded by trypsin; another cytosolic protein (21 KDa) and the membrane-bound protein (29.5 KDa) were resistant to the action of trypsin. Treatment of intact platelets with trypsin or thrombin, followed by lysis and fractionation, did not affect the binding of (α-32P)GTP to the membrane-bound protein. GTPyS still stimulates phospholipase C in permeabilized platelets already preincubated with trypsin. This suggests that trypsin-resistant GTP-binding proteins might regulate phospholipase C stimulated by GTPyS. We have started to purify the membrane-bound, trypsin-resistant, GTP-binding protein. Purification includes 1 M NaCl extraction and the use of an FPLC system with successive phenyl superose and superose 12 columns.
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Maiti, Sudipta. "Plasmonics for Membrane Proteins?" In International Conference on Fibre Optics and Photonics. Washington, D.C.: OSA, 2014. http://dx.doi.org/10.1364/photonics.2014.s3d.1.

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Park, Jeong-Man. "Interactions between membrane proteins". In Third tohwa university international conference on statistical physics. AIP, 2000. http://dx.doi.org/10.1063/1.1291595.

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Ghazikhani, Hamed, e Gregory Butler. "TooT-BERT-M: Discriminating Membrane Proteins from Non-Membrane Proteins using a BERT Representation of Protein Primary Sequences". In 2022 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB). IEEE, 2022. http://dx.doi.org/10.1109/cibcb55180.2022.9863026.

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Soares, T. A., T. P. Straatsma, Theodore E. Simos e George Maroulis. "Towards Simulations of Outer Membrane Proteins in Lipopolysaccharide Membranes". In COMPUTATIONAL METHODS IN SCIENCE AND ENGINEERING: Theory and Computation: Old Problems and New Challenges. Lectures Presented at the International Conference on Computational Methods in Science and Engineering 2007 (ICCMSE 2007): VOLUME 1. AIP, 2007. http://dx.doi.org/10.1063/1.2836008.

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Creasy, M. Austin, e Donald J. Leo. "Modeling Bilayer Systems as Electrical Networks". In ASME 2010 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2010. http://dx.doi.org/10.1115/smasis2010-3791.

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Bilayers are synthetically made cell membranes that are used to study cell membrane properties or make functional devices that use the properties of the cell membrane components. Lipids and proteins are two of the main components of a cell membrane. Lipids are amphiphilic molecules that can self assemble into organized structures in the presences of water and this self assembly property can be used to form bilayers. Because of the amphiphilic nature of the lipids, a bilayer is impermeable to ion flow. Proteins are the active structures of a cell membrane that opens pores through the membrane for ions and other molecules to pass. Proteins are made from amino acids and have varying properties that depend on its configuration. Some proteins are activated by reactions (chemical, thermal, etc) or gradients induced across the bilayer. One way of testing bilayers to find bilayer properties is to induce a potential gradient across a membrane that induces ion flow and this flow can be measured as an electrical current. But, these pores may be voltage gated or activated by some other stimuli and therefore cannot be modeled as a linear conductor. Usually the conductance of the protein is a nonlinear function of the input that activates the protein. A small system that consists of a single bilayer and protein with few changing components can be easily modeled, but as systems become larger with multiple bilayers, multiple variables, and multiple proteins, the models will become more complex. This paper looks at how to model a system of multiple bilayers and the peptide alamethicin. An analytical expression for this peptide is used to match experimental data and a short study on the sensitivity of the variables is performed.
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Golmohammadi, Seyed Koosha, Lukasz Kurgan, Brendan Crowley e Marek Reformat. "Classification of Cell Membrane Proteins". In 2007 Frontiers in the Convergence of Bioscience and Information Technologies. IEEE, 2007. http://dx.doi.org/10.1109/fbit.2007.21.

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Faiz, Mehwish, Areej Ahmed e Sumaya Abid. "Discriminating plasma membrane, internal membrane, and organelle membrane proteins by SVM". In 2021 4th International Conference on Computing & Information Sciences (ICCIS). IEEE, 2021. http://dx.doi.org/10.1109/iccis54243.2021.9676407.

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Cuppoletti, John. "Composite Synthetic Membranes Containing Native and Engineered Transport Proteins". In ASME 2008 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2008. http://dx.doi.org/10.1115/smasis2008-449.

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Our membrane transport protein laboratory has worked with material scientists, computational chemists and electrical and mechanical engineers to design bioactuators and sensing devices. The group has demonstrated that it is possible to produce materials composed native and engineered biological transport proteins in a variety of synthetic porous and solid materials. Biological transport proteins found in nature include pumps, which use energy to produce gradients of solutes, ion channels, which dissipate ion gradients, and a variety of carriers which can either transport substances down gradients or couple the uphill movement of substances to the dissipation of gradients. More than one type of protein can be reconstituted into the membranes to allow coupling of processes such as forming concentration gradients with ion pumps and dissipating them with an ion channel. Similarly, ion pumps can provide ion gradients to allow the co-transport of another substance. These systems are relevant to bioactuation. An example of a bioactuator that has recently been developed in the laboratory was based on a sucrose-proton exchanger coupled to a proton pump driven by ATP. When coupled together, the net reaction across the synthetic membrane was ATP driven sucrose transport across a flexible membrane across a closed space. As sucrose was transported, net flow of water occurred, causing pressure and deformation of the membrane. Transporters are regulated in nature. These proteins are sensitive to voltage, pH, sensitivity to a large variety of ligands and they can be modified to gain or lose these responses. Examples of sensors include ligand gated ion channels reconstituted on solid and permeable supports. Such sensors have value as high throughput screening devices for drug screening. Other sensors that have been developed in the laboratory include sensors for membrane active bacterial products such as the anthrax pore protein. These materials can be self assembled or manufactured by simple techniques, allowing the components to be stored in a stable form for years before (self) assembly on demand. The components can be modified at the atomic level, and are composed of nanostructures. Ranges of sizes of structures using these components range from the microscopic to macroscopic scale. The transport proteins can be obtained from natural sources or can be produced by recombinant methods from the genomes of all kingdoms including archea, bacteria and eukaryotes. For example, the laboratory is currently studying an ion channel from a thermophile from deep sea vents which has a growth optimum of 90 degrees centigrade, and has membrane transport proteins with very high temperature stability. The transport proteins can also be genetically modified to produce new properties such as activation by different ligands or transport of new substances such as therapeutic agents. The structures of many of these proteins are known, allowing computational chemists to help understand and predict the transport processes and to guide the engineering of new properties for the transport proteins and the composite membranes. Supported by DARPA and USARMY MURI Award and AFOSR.
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Rapporti di organizzazioni sul tema "Membrane proteins"

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Woolf, Thomas B., Paul Stewart Crozier e Mark Jackson Stevens. Molecular dynamics of membrane proteins. Office of Scientific and Technical Information (OSTI), ottobre 2004. http://dx.doi.org/10.2172/919637.

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Shirley, David Noyes, Thomas W. Hunt, W. Michael Brown, Joseph S. Schoeniger, Alexander Slepoy, Kenneth L. Sale, Malin M. Young, Jean-Loup Michel Faulon e Genetha Anne Gray. Model-building codes for membrane proteins. Office of Scientific and Technical Information (OSTI), gennaio 2005. http://dx.doi.org/10.2172/920776.

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Smith, H. G. Surface-Bound Membrane-Mimetic Assemblies: Electrostatic Attributes of Integral Membrane Proteins. Fort Belvoir, VA: Defense Technical Information Center, ottobre 1988. http://dx.doi.org/10.21236/ada204381.

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Smith, H. G. Surface-Bound Membrane-Mimetic Assemblies: Electrostatic Attributes of Integral Membrane Proteins. Fort Belvoir, VA: Defense Technical Information Center, giugno 1991. http://dx.doi.org/10.21236/ada237229.

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Williams, Timothy J., Ramesh Balakrishnan, Brian K. Radak, James C. Phillips, Wei Jiang, Sunhwan Jo, Laxmikant V. Kale, Klaus Schulten e Benoit Roux. Free Energy Landscapes of Membrane Transport Proteins. Office of Scientific and Technical Information (OSTI), settembre 2017. http://dx.doi.org/10.2172/1483996.

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Creutz, Carl E. Repair of Nerve Cell Membrance Damage by Calcium-Dependent, Membrane-Binding Proteins. Fort Belvoir, VA: Defense Technical Information Center, settembre 2013. http://dx.doi.org/10.21236/ada596750.

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Creutz, Carl E. Repair of Nerve Cell Membrane Damage by Calcium-Dependent, Membrane-Binding Proteins. Fort Belvoir, VA: Defense Technical Information Center, settembre 2011. http://dx.doi.org/10.21236/ada560549.

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Barkan, Alice, e Zach Adam. The Role of Proteases in Regulating Gene Expression and Assembly Processes in the Chloroplast. United States Department of Agriculture, gennaio 2003. http://dx.doi.org/10.32747/2003.7695852.bard.

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Abstract (sommario):
Chloroplasts house many biochemical processes that are essential for plant viability. Foremost, among these is photosynthesis, which requires the protein-rich thylakoid membrane system. The activation of chloroplast genes encoding thylakoid membrane proteins and the targeting and assembly of these proteins together with their nuclear-encoded partners are essential for the elaboration of the thylakoid membrane. Several nuclear-encoded proteins that regulate chloroplast gene expression and that mediate the targeting of proteins to the thylakoid membrane have been identified in recent years, and many more remain to be discovered. The abundance of such proteins is critical and is likely to be determined to a significant extent by their stability, which in turn, is influenced by chloroplast protease activities. The primary goal of this project was to link specific proteases to specific substrates, and in particular, to specific regulatory and assembly proteins. We proposed a two-pronged approach, involving genetic analysis of the consequences of the mutational loss of chloroplast proteases, and biochemical analysis of the degradation pathways of specific proteins that have been shown to control chloroplast gene expression. Our initial bioinformatic analysis of chloroplast proteases allowed us to identify the set of pro teases that is targeted to the chloroplast. We used that information to recover three Arabidopsis mutants with T - DNA insertions in specific chloroplast protease genes. We carried out the first analysis of the stability of a regulator of chloroplast gene expression (CRS2), and found that the protein is much less stable than are typical components of the photosynthetic apparatus. Genetic reagents and analytical methods were developed that have set the stage for a rapid advancement of our understanding of chloroplast proteolysis. The results obtained may be useful for manipulating the expression of transgenes in the chloroplast and for engineering plants whose photosynthetic activity is optimized under harsh environmental conditions.
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Moczydlowski, Edward G. Intra-membrane molecular interactions of K+ channel proteins :. Office of Scientific and Technical Information (OSTI), luglio 2013. http://dx.doi.org/10.2172/1092995.

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Schiffer, M., C. H. Chang e F. J. Stevens. The functions of tryptophan residues in membrane proteins. Office of Scientific and Technical Information (OSTI), agosto 1994. http://dx.doi.org/10.2172/10172497.

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