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Letteratura scientifica selezionata sul tema "Membrane, Basement"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 20 febbraio 2023

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Articoli di riviste sul tema "Membrane, Basement"

1

Murshed, Monzur, Neil Smyth, Nicolai Miosge, Jörg Karolat, Thomas Krieg, Mats Paulsson e Roswitha Nischt. "The Absence of Nidogen 1 Does Not Affect Murine Basement Membrane Formation". Molecular and Cellular Biology 20, n. 18 (15 settembre 2000): 7007–12. http://dx.doi.org/10.1128/mcb.20.18.7007-7012.2000.

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ABSTRACT Nidogen 1 is a highly conserved protein in mammals,Drosophila melanogaster, Caenorhabditis elegans, and ascidians and is found in all basement membranes. It has been proposed that nidogen 1 connects the laminin and collagen IV networks, so stabilizing the basement membrane, and integrates other proteins, including perlecan, into the basement membrane. To define the role of nidogen 1 in basement membranes in vivo, we produced a null mutation of the NID-1 gene in embryonic stem cells and used these to derive mouse lines. Homozygous animals produce neither nidogen 1 mRNA nor protein. Surprisingly, they show no overt abnormalities and are fertile, their basement membrane structures appearing normal. Nidogen 2 staining is increased in certain basement membranes, where it is normally only found in scant amounts. This occurs by either redistribution from other extracellular matrices or unmasking of nidogen 2 epitopes, as its production does not appear to be upregulated. The results show that nidogen 1 is not required for basement membrane formation or maintenance.

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2

Hagedorn, Elliott J., Joshua W. Ziel, Meghan A. Morrissey, Lara M. Linden, Zheng Wang, Qiuyi Chi, Sam A. Johnson e David R. Sherwood. "The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo". Journal of Cell Biology 201, n. 6 (10 giugno 2013): 903–13. http://dx.doi.org/10.1083/jcb.201301091.

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Though critical to normal development and cancer metastasis, how cells traverse basement membranes is poorly understood. A central impediment has been the challenge of visualizing invasive cell interactions with basement membrane in vivo. By developing live-cell imaging methods to follow anchor cell (AC) invasion in Caenorhabditis elegans, we identify F-actin–based invadopodia that breach basement membrane. When an invadopodium penetrates basement membrane, it rapidly transitions into a stable invasive process that expands the breach and crosses into the vulval tissue. We find that the netrin receptor UNC-40 (DCC) specifically enriches at the site of basement membrane breach and that activation by UNC-6 (netrin) directs focused F-actin formation, generating the invasive protrusion and the cessation of invadopodia. Using optical highlighting of basement membrane components, we further demonstrate that rather than relying solely on proteolytic dissolution, the AC’s protrusion physically displaces basement membrane. These studies reveal an UNC-40–mediated morphogenetic transition at the cell–basement membrane interface that directs invading cells across basement membrane barriers.

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3

Nazari, Shayan S., Andrew D. Doyle e Kenneth M. Yamada. "Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel". Gels 8, n. 9 (7 settembre 2022): 567. http://dx.doi.org/10.3390/gels8090567.

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Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes. Here, we used a three-dimensional in vitro invasion model consisting of cancer spheroids encapsulated by a basement membrane and embedded in 3D collagen gels to visualize the early events of cancer invasion by confocal microscopy and live-cell imaging. Human breast cancer cells generated large numbers of basement membrane perforations, or holes, of varying sizes that expanded over time during cell invasion. We used a wide variety of small molecule inhibitors to probe the mechanisms of basement membrane perforation and hole expansion. Protease inhibitor treatment (BB94), led to a 63% decrease in perforation size. After myosin II inhibition (blebbistatin), the basement membrane perforation area decreased by only 15%. These treatments produced correspondingly decreased cellular breaching events. Interestingly, inhibition of actin polymerization dramatically decreased basement membrane perforation by 80% and blocked invasion. Our findings suggest that human cancer cells can primarily use proteolysis and actin polymerization to perforate the BM and to expand perforations for basement membrane breaching with a relatively small contribution from myosin II contractility.

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LAURIE, G. W., e C. P. LEBLOND. "Basement membrane nomenclature". Nature 313, n. 6000 (gennaio 1985): 272. http://dx.doi.org/10.1038/313272b0.

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5

Weber, Manfred. "Basement membrane proteins". Kidney International 41, n. 3 (marzo 1992): 620–28. http://dx.doi.org/10.1038/ki.1992.95.

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6

Gunwar, Sripad, Fernando Ballester, Milton E. Noelken, Yoshikazu Sado, Yoshifumi Ninomiya e Billy G. Hudson. "Glomerular Basement Membrane". Journal of Biological Chemistry 273, n. 15 (10 aprile 1998): 8767–75. http://dx.doi.org/10.1074/jbc.273.15.8767.

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7

Ray, Marilyn C., e Leonard E. Gately. "Basement membrane zone". Clinics in Dermatology 14, n. 4 (luglio 1996): 321–30. http://dx.doi.org/10.1016/0738-081x(96)00061-2.

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8

Li, A. C. Y. "Basement membrane components". Journal of Clinical Pathology 56, n. 12 (1 dicembre 2003): 885–87. http://dx.doi.org/10.1136/jcp.56.12.885.

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9

Eady, Robin A. J. "The Basement Membrane". Archives of Dermatology 124, n. 5 (1 maggio 1988): 709. http://dx.doi.org/10.1001/archderm.1988.01670050053021.

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10

Bosman, Fred T., Jack Cleutjens, Cor Beek e Michael Havenith. "Basement membrane heterogeneity". Histochemical Journal 21, n. 11 (novembre 1989): 629–33. http://dx.doi.org/10.1007/bf01002481.

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Tesi sul tema "Membrane, Basement"

1

Cleutjens, Jacobus Peter Marie. "Basement membrane heterogeneity". Maastricht : Maastricht : Rijksuniversiteit Limburg ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5472.

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2

Wootton, Andrew. "The glomerular basement membrane and nephritis /". Title page, contents and abstract only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phw918.pdf.

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3

Devaka, K. Weerakoon Cheung H. Tak. "Interaction of macrophages with the basement membrane". Normal, Ill. Illinois State University, 1995. http://wwwlib.umi.com/cr/ilstu/fullcit?p9603526.

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Thesis (Ph. D.)--Illinois State University, 1995.
Title from title page screen, viewed May 8, 2006. Dissertation Committee: Hou Tak Cheung (chair), David W. Borst, Herman E. Brockman, Alan J. Katz, Anthony J. Otsuka. Includes bibliographical references (leaves 98-110) and abstract. Also available in print.

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4

Visser, Robbert. "Basement membrane antigens in preneoplastic and neoplastic conditions". Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1993. http://arno.unimaas.nl/show.cgi?fid=5867.

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Melian, Nadia. "Basement membrane composition of Dag1 null chimaeric mice kidneys". Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33809.

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The growth of an organism involves the proliferation and migration of cells within an extracellular matrix. As a cell surface receptor, the Dag1 gene product dystroglycan links the intracellular cytoskeleton to the extracellular basement membrane in many cells. Thought to act as a structural protein dystroglycan may also participate in signal transduction. This study aims to better understand the role of dystroglycan during kidney morphogenesis. I hypothesised that a lack of dystroglycan in the precursor cells of the kidney could lead to altered kidney growth. Chimaeric mice deficient in dystroglycan were generated to test this hypothesis. A total of 38 chimaeras had genetic contribution and histological analysis performed on their kidneys. Of the chimaeras analysed, only four demonstrated altered kidney morphology. Further histological, immunohistochemical and biochemical studies established whether a link existed between this morphology and a deficiency in dystroglycan. Normal laminar architecture and nephrotic structures of the kidneys suggest that normal kidney organogenesis occurred in the absence of dystroglycan. The pattern and expression level of basement membrane components suggests that normal basement membrane formation also occured in the absence of dystroglycan. Biochemical analysis revealed that although dystroglycan protein levels correlate with the genetic contribution of the chimaeric kidney, it does not correlate with the altered morphology. Ureter blockage causing hydronephrosis can explain the morphology observed. A deficiency of dystroglycan in the ureter may in turn have caused this blockage. These findings suggest that dystroglycan is not necessary for kidney organogenesis, since kidney development occurred normally in all 38 chimaeric animals irrespective of genetic contribution.

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Burton, Victoria Jane. "Neutrophil migration through endothelial cells and their basement membrane". Thesis, University of Birmingham, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532273.

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Forster, Simon J. "Basement membrane proteins and the spread of rectal cancer". Thesis, University of Leicester, 1987. http://hdl.handle.net/2381/35223.

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Antisera to the basement membrane proteins laminin, fibronectin and type IV collagen were prepared, characterized and rendered monospecific by appropriate treatments. Methods were developed to allow the use of these antisera for inmunohistochemical staining of sections of tissue which had been preserved by several methods. In particular, the use of protease digestion {"unmasking") to allow staining of formalin-fixed, paraffin-embedded material was studied. The presence and intensity of staining was found to be highly dependent on the protease and the conditions of digestion, the type of basement membrane, and whether the tissue was normal or neoplastic. The distributions of the three proteins were studied in normal colorectal mucosa and in colorectal adenocarcinoma. A detailed retrospective study was made of the distribution of laminin in 158 cases of rectal carcinoma. Tumours fell into two groups: those which showed linear basement membrane-like laminin staining (laminin positive) and those which did not (laminin negative). Patients with laminin positive tumours had a reduced incidence of distant metastasis and an increased 5 yr survival rate; these correlations were statistically highly significant. Carparison by multivariate analysis with other widely used prognostic markers indicated that laminin status has considerable potential for use as a prognostic marker in the management of such patients. The antisera were also used in a study of the cellular origin and biosynthesis of basement membrane proteins in three systems. In a basement membrane-producing murine tumour, intracellular staining was seen, but it was found that different methods of tissue preparation and unmasking drastically affected the apparent distributions of the three antigens. In the developing rat intestine, no evidence was seen of basement membrane synthesis by the intestinal epithelial cells. However in isolated rat intestinal epithelial cells, some evidence was found for synthesis of laminin and fibronectin, but not type IV collagen.

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Garton, Rosemary Louise. "The influence of basement membrane proteins on re-vascularization networks formed after acute injury". Thesis, The University of Sydney, 1997. http://hdl.handle.net/2123/4817.

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9

Zhang, Xu. "Basal lamina genes affected in leiomyomatosis and congenital muscular dystrophy : structure and mutation analyses of the collagen COL4A6 and laminin LAMA2 genes". Stockholm, 1997. http://diss.kib.ki.se/1997/91-628-2780-4.

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10

Li, Yi-Yang Cheung H. Tak. "Basement membrane and its components on lymphocyte adhesion, migration, and proliferation". Normal, Ill. Illinois State University, 1992. http://wwwlib.umi.com/cr/ilstu/fullcit?p9234466.

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Thesis (Ph. D.)--Illinois State University, 1992.
Title from title page screen, viewed January 27, 2006. Dissertation Committee: H. Tak Cheung (chair), Anthony Otsuka, Alan Katz, Brian Wilkinson, David Weber. Includes bibliographical references (leaves 108-120) and abstract. Also available in print.

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Libri sul tema "Membrane, Basement"

1

International Symposium on Glomerular Basement Membrane (2nd 1983 Vienna). Glomerular basement membrane: Contributions to the 2nd International Symposium on Glomerular Basement Membrane, Vienna, September 1983. A cura di Lubec Gert e Hudson Billy G. London: Libbey, 1985.

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2

International Symposium on Glomerular Basement Membrane (2nd 1983 Vienna, Austria). Glomerular basement membrane: Contributions to the 2nd International Symposium on Glomerular Basement Membrane, Vienna, September 1983. A cura di Hudson Billy G e Lubec Gert. London: Libbey, 1985.

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3

Kefalides, Nicholas A. Basement membranes: Cell and molecular biology. San Diego, CA: Elsevier/Academic Press, 2006.

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4

P, Borel Jacques, a cura di. Basement membranes: Cell and molecular biology. Amsterdam: Elsevier Academic Press, 2005.

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5

Membranes, International Symposium on Renal Basement. Progress in basement membrane research: Renal and related aspects in health and disease : proceedings. London: J. Libbey, 1988.

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6

Marie-Claire, Gubler, e Sternberg Michel, a cura di. Progress in basement membrane research: Renal and related aspects in health and disease : proceedings of the IVth International Symposium on Renal Basement Membranes and Related Research held in Paris, 21-25 July 1987. London: Libbey, 1988.

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7

International Symposium on Basement Membranes (1985 Mishima-shi, Japan). Basement membranes: Proceedings of the International Symposium on Basement Membranes held in Mishima (Japan) on June 24-26, 1985. Amsterdam: Elsevier Science Publishers, 1985.

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8

Costigan, Michael. Basement membrane gene expression in the normal and streptozotocin diabetic rat. Manchester: Universityof Manchester, 1996.

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9

Hikaru, Koide, e Hayashi T, a cura di. Extracellular matrix in the kidney: 6th International Symposium on Basement Membrane, Shizuoka, May 29-June 1, 1993. Basel: Karger, 1994.

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10

Kalaaji, Amer N. Mayo Clinic atlas of immunofluorescence in dermatology: Patterns and target antigens. Rochester, MN: Mayo Clinic Scientific Press, 2006.

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Capitoli di libri sul tema "Membrane, Basement"

1

Berry, Colin, Jason M. Meyer, Marjorie A. Hoy, John B. Heppner, William Tinzaara, Clifford S. Gold, Clifford S. Gold et al. "Basement Membrane". In Encyclopedia of Entomology, 399. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_241.

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Pavelka, Margit, e Jürgen Roth. "Basement Membrane". In Functional Ultrastructure, 180–81. Vienna: Springer Vienna, 2010. http://dx.doi.org/10.1007/978-3-211-99390-3_94.

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Moses, Marsha A. "Basement Membrane". In Encyclopedia of Systems Biology, 70. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_1535.

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Pavelka, Margit, e Jürgen Roth. "Glomerular Basement Membrane". In Functional Ultrastructure, 182. Vienna: Springer Vienna, 2010. http://dx.doi.org/10.1007/978-3-211-99390-3_95.

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5

Schoumacher, Marie, Alexandros Glentis, Vasily V. Gurchenkov e Danijela M. Vignjevic. "Basement Membrane Invasion Assays: Native Basement Membrane and Chemoinvasion Assay". In Adhesion Protein Protocols, 133–44. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-538-5_8.

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6

Inai, Kei, Alexander K. C. Leung, Jouni Uitto, Gerhard-Paul Diller, Michael A. Gatzoulis, John-John B. Schnog, Victor E. A. Gerdes et al. "Epithelial Basement Membrane Dystrophy". In Encyclopedia of Molecular Mechanisms of Disease, 604–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_3296.

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Raj, Satish R., S. R. Wayne Chen, Robert S. Sheldon, Arti N. Shah, Bharat K. Kantharia, Ulrich Salzer, Bodo Grimbacher et al. "Thin Basement Membrane Nephropathy". In Encyclopedia of Molecular Mechanisms of Disease, 2045. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_8692.

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8

Pedchenko, Vadim, e Ambra Pozzi. "Basement Membrane Collagens and Cancer". In Cell-Extracellular Matrix Interactions in Cancer, 65–85. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-0814-8_4.

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Benchimol, Corinne. "Anti-glomerular Basement Membrane Disease". In Glomerulonephritis, 359–66. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-49379-4_19.

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Kirkpatrick, C. James, Helma Rixen, Thomas Axer, Ursula Schmitz, Guenter Hollweg, Doris Klee, Rudi Wajda, Martin Kampe, Eike Fischer e Christian Mittermayer. "Endothelial Cell-Basement Membrane Interactions". In Vascular Dynamics, 135–48. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-7856-3_11.

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Atti di convegni sul tema "Membrane, Basement"

1

Amini, Rouzbeh, Alina Oltean, Vincent Barnett, Yoav Segal e Victor H. Barocas. "Mechanical Properties of the Porcine Lens Capsule". In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192664.

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Basement membranes are ubiquitous. In humans, genetic disorders in basement membranes can lead to many complications including kidney disease, skeletal muscle myopathy, hearing loss, and ocular abnormalities[1]. We hypothesize that genetic mutation of the microstructure of the lens capsule basement membrane will alter its mechanical properties. Because of its unique thickness and anatomically distinct margins, the lens capsule is the only site in the body where large-scale mechanical tests on the basement membrane can be made.

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Agalsoff, Kellie M., e Saami K. Yazdani. "Matrigel as a Basement Membrane: A Feasibility Study". In 2016 32nd Southern Biomedical Engineering Conference (SBEC). IEEE, 2016. http://dx.doi.org/10.1109/sbec.2016.30.

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Hallgren, Oskar, Elisabet Wieslander, Martina Kvist Reimer, Magnus Dahlbäck, Leif Eriksson, Leif Bjermer, Jonas S. Erjefalt, Claes G. Lofdahl e Gunilla Westergren-Thorsson. "Patchy Alterations Of The Airway Basement Membrane In COPD". In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5246.

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4

Pastor-Pareja, Jose C. "Basement membrane secretion, assembly, and fibrotic misassembly inDrosophila melanogaster". In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.106550.

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Powell, Tracy A., Rouzbeh Amini, Alina Oltean, Vincent A. Barnett, Kevin D. Dorfman, Yoav Segal e Victor H. Barocas. "Elasticity of the Lens Capsule as Measured by Osmotic Swelling". In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19487.

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Basement membranes are planar extracellular matrices ubiquitous within tissues and serve roles in the organization, support and regulation of resident cell populations. The ocular lens capsule is experimentally accessible accounting for its wide use as a model in studies of basement membrane mechanics [1–3]. Optical tracking of passive osmotic swelling, unlike previously employed methods of determining the elasticity of the lens capsule, involves minimal manipulation of the lens, which is desirable when using smaller animal models, such as the mouse.

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Gyoneva, Lazarina, Mohammad F. Hadi, Yoav Segal, Kevin D. Dorfman e Victor H. Barocas. "Role of Lateral Interactions in Type IV Collagen Network Mechanics". In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14625.

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The basement membrane is a specialized part of the extra-cellular matrix. It is usually characterized as a scaffold for epithelial cells but in some tissues it serves other, mechanical, roles [1]. The mechanical properties of the basement membrane are mainly determined by one of its main constituents — type IV collagen. Unlike the well-known fibrous type I collagen, collagen IV assembles into planar networks (Fig. 1) [2]. The α 1(IV) and α 2(IV) collagen IV chains assemble into the so-called major chain network, present in all basement membranes. The α 3(IV), α 4(IV), α 5(IV) collagen IV chains form the minor chain network which is found only in the adult basement membranes of the kidney glomerular capillaries (GBM), ocular lens (LBM), cochlea, and the testes [3]. The minor chains have a higher number of cysteine residues, allowing them to form a higher number of lateral interactions. In the minor chain network, the greater potential to interact laterally manifests in the formation of super-coils, which are rarely observed in the major chain network [4]. Increasing the number of cross-links in a polymeric material is known to increase material stiffness; therefore, it is believed that the minor chain network confers basement membranes with additional strength and stability [5]. In the hereditary disease Alport syndrome, a mutation causes the absence of the minor chain network. The GBM and LBM of Alport patients appear weakened and unable to meet their mechanical demands, further supporting this theory [6]. The objective of this study was to evaluate the importance of cross-linking in the minor chains for the mechanical properties of type IV collagen networks, specifically in the GBM and LBM where the absence of the minor chains has an observed mechanical effect.

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Tossin, Gabriel Pereira, Isabela Bulhões Faganello, Sthefanny Josephine Klein Otton Guedes, Vitor Augusto Takahashi Diniz, Monique Evelyn Venturin, Ághata Silvestre Ferraz, Gabriela Zimmermann, Nicole Jansen Rabello, Ana Paula Adame e Marcio Augusto Nogueira. "GRANULOMATOSIS WITH POLYANGIITIS ASSOCIATED TO ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE". In XXXIX Congresso Brasileiro de Reumatologia. Sociedade Brasileiro de Reumatologia, 2022. http://dx.doi.org/10.47660/cbr.2022.2193.

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Ong, Sim Heng, S. T. Giam, X. Jayasooriah e R. Sinniah. "Semiautomated detection and measurement of glomerular basement membrane from electron micrographs". In Medical Imaging V: Image Processing, a cura di Murray H. Loew. SPIE, 1991. http://dx.doi.org/10.1117/12.45253.

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9

Jandl, Katharina, Leigh M. Marsh, Julia Hoffmann, Ayse Ceren Mutgan, Oliver Baum, Wilhelm Bloch, Katharina Sinn et al. "Basement membrane, a specialized extracellular matrix, shapes endothelial function in IPAH". In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1488.

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Josephson, Maureen B., e Ronald C. Rubenstein. "Anti-Glomerular Basement Membrane Antibody In An Infant with Pulmonary Hemosiderosis". In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6209.

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