Letteratura scientifica selezionata sul tema "Lytic granule"
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Articoli di riviste sul tema "Lytic granule":
HSU, HSIANG-TING, Dixita Viswanath, Emily Mace, Athanasia Christakou, Martin Wiklund, Björn Önfelt e Jordan Orange. "Lytic granule convergence is essential for NK cells to promote targeted killing while preventing collateral damage". Journal of Immunology 196, n. 1_Supplement (1 maggio 2016): 131.6. http://dx.doi.org/10.4049/jimmunol.196.supp.131.6.
Pattu, Varsha, Mahantappa Halimani, Monika Peuschel, Elmar Krause e Jens Rettig. "Regulation of lytic granules for normal cytotoxic T lymphocyte function (P1140)". Journal of Immunology 190, n. 1_Supplement (1 maggio 2013): 64.17. http://dx.doi.org/10.4049/jimmunol.190.supp.64.17.
Pattu, Varsha, Ulf Matti, Mahantappa Halimani, Lisa Weins e Jens Rettig. "Identification of the v-SNARE required for lytic granule fusion in cytotoxic T lymphocytes (176.27)". Journal of Immunology 188, n. 1_Supplement (1 maggio 2012): 176.27. http://dx.doi.org/10.4049/jimmunol.188.supp.176.27.
Burkhardt, J. K., J. M. McIlvain, M. P. Sheetz e Y. Argon. "Lytic granules from cytotoxic T cells exhibit kinesin-dependent motility on microtubules in vitro". Journal of Cell Science 104, n. 1 (1 gennaio 1993): 151–62. http://dx.doi.org/10.1242/jcs.104.1.151.
Wilton, Katelynn Marie, e Daniel D. Billadeau. "Vasodilator Stimulated Phosphoprotein (VASP)-Mediated Actin Polymerization Drives Natural Killer Cell Granule Convergence". Journal of Immunology 200, n. 1_Supplement (1 maggio 2018): 170.7. http://dx.doi.org/10.4049/jimmunol.200.supp.170.7.
Liu, Dongfang, Tobias Meckel e Eric Long. "Distinct Roles of Rab27a in Lytic Granule Movement at the Plasma Membrane and in the Cytosol (89.47)". Journal of Immunology 184, n. 1_Supplement (1 aprile 2010): 89.47. http://dx.doi.org/10.4049/jimmunol.184.supp.89.47.
Peña, S. V., D. A. Hanson, B. A. Carr, T. J. Goralski e A. M. Krensky. "Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins." Journal of Immunology 158, n. 6 (15 marzo 1997): 2680–88. http://dx.doi.org/10.4049/jimmunol.158.6.2680.
Sanborn, Keri B., Gregory D. Rak, Saumya Y. Maru, Analisa Difeo, John A. Martignetti, Remi Favier, Pinaki P. Banerjee e Jordan S. Orange. "Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse (134.13)". Journal of Immunology 182, n. 1_Supplement (1 aprile 2009): 134.13. http://dx.doi.org/10.4049/jimmunol.182.supp.134.13.
Kurowska, Mathieu, Nicolas Goudin, Nadine T. Nehme, Magali Court, Jérôme Garin, Alain Fischer, Geneviève de Saint Basile e Gaël Ménasché. "Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex". Blood 119, n. 17 (26 aprile 2012): 3879–89. http://dx.doi.org/10.1182/blood-2011-09-382556.
Halimani, Mahantappa, Varsha Pattu, Christian Junker, Misty Marshall, Eva Schwarz, Elmar Krause, Ulf Matti, Markus Hoth e Jens Rettig. "The role of syntaxin11 in cytotoxic T lymphocytes (109.26)". Journal of Immunology 186, n. 1_Supplement (1 aprile 2011): 109.26. http://dx.doi.org/10.4049/jimmunol.186.supp.109.26.
Tesi sul tema "Lytic granule":
Ming, Min [Verfasser], e Jens [Akademischer Betreuer] Rettig. "Simultaneous capacitance and TIRF measurements from lytic granule fusion in primary human cytotoxic T lymphocytes / Min Ming. Betreuer: Jens Rettig". Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2015. http://d-nb.info/1065232608/34.
Tsun, Andy. "The mechanisms underlying polarised secretion of lytic granules in cytotoxic T-Lymphocytes". Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510251.
Saeed, Mezida Bedru. "Nanoscale rearrangements in cortical actin filaments at lytic immunological synapses". Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/nanoscale-rearrangements-in-cortical-actin-filaments-at-lytic-immunological-synapses(8d00dd58-7b1a-435b-ad6c-016b12ff34d9).html.
Delage, Laure. "Des déficiences génétiques comme modèles naturels pour l'étude de la régulation des checkpoints immunitaires et la caractérisation des réponses auto-immunes". Electronic Thesis or Diss., Université Paris Cité, 2021. http://www.theses.fr/2021UNIP5190.
Recessive NBEAL2 mutations have been reported in patients with Gray Platelet Syndrome (GPS). This syndrome is characterized by a macro-thrombocytopenia, with platelets lacking alpha-granules, leading to bleeding disorders, often associated with splenomegaly. Thus, NBEAL2 plays a crucial role in the trafficking of alpha-granules in platelets. Moreover, our lab has also described NBEAL2 deficiencies in patients presenting clinical features of the autoimmune lymphoproliferative syndrome, suggesting a role of NBEAL2 in immune homeostasis and tolerance. A broader international cohort of GPS patients has been described, revealing immune system abnormalities (autoimmune diseases, autoantibodies, lymphopenia). If the role of NBEAL2 in the traffic of granules is often investigated, the exact mechanism leading to the development of autoimmune manifestations in GPS patients remains unknown. NBEAL2 belongs to a protein family involved in vesicular trafficking, all of which possess a conserved BEACH domain. Within this BEACH-domain containing proteins family, one of the closest members to NBEAL2 is LRBA. LRBA is involved in the recycling of CTLA-4, an inhibitory immune checkpoint. CTLA-4 plays a crucial role in the regulation of immune responses and tolerance. Recessive mutations of LRBA lead to similar clinical features as partial CTLA-4 deficiency: autoimmunity, lymphocytic infiltrations, and progressive B lymphopenia. Physiologically, LRBA prevents the lysosomal degradation of CTLA-4 and allows its recycling to the membrane. By analogy with LRBA, we investigated the importance of NBEAL2 in immune checkpoints intracellular trafficking and we brought new insights on its role in lymphocytes. Thus, NBEAL2 is a scaffold protein, binding LRBA, and involved in CTLA-4 trafficking as well as in vesicular trafficking in general. This work brings new knowledge to the regulation of CTLA-4 in activated T lymphocytes, a list of new partners for NBEAL2 protein and a new model of vesicular trafficking in which NBEAL2 is involved. Finally, a better understanding of the mechanisms leading to autoimmunity in patients with gray platelets syndrome could lead to better diagnosis and treatment management
Halimani, Mahantappa [Verfasser], e Jens [Akademischer Betreuer] Rettig. "Syntaxin11 serves as a t-SNARE for the final fusion step of lytic granules in human cytotoxic t lymphocytes / Mahantappa Halimani. Betreuer: Jens Rettig". Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2014. http://d-nb.info/105372523X/34.
Lima, Patricia Daniele Azevedo 1984. "Dualidade funcional das células uNK de camundongos durante a gestação". [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316901.
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: Células Natural Killer uterina (uNK) produzem moléculas angiogênicas e citocinas críticas ao sucesso da gestação , assim como proteínas citolíticas relacionadas à resposta imune inata. Contudo, se as capacidades angiogênicas e citolíticas são provenientes de diferentes subpopulações de células uNK não é conhecido; da mesma forma, estes fenótipos ainda não são estabelecidos. Assim, a proposta inicial deste trabalho foi avaliar...Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da tese digital
Abstract: Angiogenic and cytokine molecules produced by uterine natural killer (uNK) cells are critical for successful pregnancy. Cytolytic proteins are also express by uNK cells. However, it is unknown whether the angiogenic and cytolytic capacities are from different uNK subsets, or the same cells. Thus, we initially proposed to evaluate...Note: The complete abstract is available with the full electronic document
Doutorado
Histologia
Doutor em Biologia Celular e Estrutural
Pattu, Varsha [Verfasser]. "Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes / vorgelegt von Varsha Pattu". 2009. http://d-nb.info/100660121X/34.
Battistuzzi, Susan C. "Basic fibroblast growth factor-induced proliferation in mouse embryonic fibroblasts augments their cytolysis by NK cell-derived lytic granules". 1992. http://hdl.handle.net/1993/17441.
Qu, Bin [Verfasser]. "Vti1b-dependent interaction between lytic granules and recycling TCR compartments is required for efficient function of cytotoxic T lyphocytes / vorgelegt von Bin Qu". 2009. http://d-nb.info/1006896384/34.
Capitoli di libri sul tema "Lytic granule":
Capitani, Nagaja, Chiara Cassioli, Keerthana Ravichandran e Cosima T. Baldari. "Exploiting the RUSH System to Study Lytic Granule Biogenesis in Cytotoxic T Lymphocytes". In The Immune Synapse, 421–36. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3135-5_27.
Müller, Sabina, Liza Filali, Marie-Pierre Puissegur e Salvatore Valitutti. "Measuring CTL Lytic Granule Secretion and Target Cell Membrane Repair by Fluorescent Lipophilic Dye Uptake at the Lytic Synapse". In The Immune Synapse, 463–76. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3135-5_30.
Hsu, Hsiang-Ting, Alexandre F. Carisey e Jordan S. Orange. "Measurement of Lytic Granule Convergence After Formation of an NK Cell Immunological Synapse". In The Immune Synapse, 497–515. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6881-7_31.
Griffiths, G. M., e Y. Argon. "Structure and Biogenesis of Lytic Granules". In Pathways for Cytolysis, 39–58. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79414-8_3.
Schirra, Claudia, Nadia Alawar, Ute Becherer e Hsin-Fang Chang. "Separation of Single Core and Multicore Lytic Granules by Subcellular Fractionation and Immunoisolation". In The Immune Synapse, 159–67. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3135-5_11.
"IL-2 Mediated Induction of Lytic Granules, Perforin, and BLT-Esterase in Potent, Granule-Free Cytolytic T Lymphocytes Indicates an Alternative Function of Lytic Granules". In Lymphocyte Activation and Differentiation, 669–72. De Gruyter, 1988. http://dx.doi.org/10.1515/9783110850253-105.
Scharrig, Emilia, Maria L. Sanmillan e Claudio G. Giraudo. "Analysis of immune synapses by τau-STED imaging and 3D-quantitative colocalization of lytic granule markers". In Methods in Cell Biology. Elsevier, 2023. http://dx.doi.org/10.1016/bs.mcb.2023.01.018.
Donovan, J. P. "Thomas Love Peacock". In Literature of the Romantic Period, 269–83. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780198711209.003.0013.