Bibliografie tematiche / Long-Term efficaccy

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Letteratura scientifica selezionata sul tema "Long-Term efficaccy"

Autore: Grafiati

Pubblicato: 14 dicembre 2024

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Libri sul tema "Long-Term efficaccy"

Braddock, Kathleen. Electroconvulsive Therapy: Clinical Uses, Efficacy and Long-Term Health Effects. Nova Science Publishers, Incorporated, 2014.

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Tucker, Sharon Joann. THE LONG-TERM EFFICACY OF A BEHAVIORAL PARENT TRAINING INTERVENTION FOR FAMILIES WITH TWO-YEAR-OLDS. 1996.

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Sayal, Puneet, and Jianren Mao. Opioids in Spine Pain: Indications, Challenges, and Controversies. Edited by Mehul J. Desai. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199350940.003.0029.

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Abstract (sommario):

Opioid medications are commonly used in the treatment of spine-mediated pain. They are used on a chronic, long-term basis, and their use is on the rise. The available evidence supports their use for short periods if much effort is put into patient and opioid selection, and with close monitoring. Challenges include numerous adverse effects, aberrant behaviors, and the comfort and skill set of providers. Controversies surrounding the chronic use of opioids center on the inconclusive evidence regarding long-term efficacy and safety. More research is necessary to determine whether these medications are appropriate, efficacious, and safe over the long term, and also to aid providers in managing patients on chronic opioids in terms of patient and opioid selection, risk stratification, monitoring, and discontinuation/weaning.

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Castle, David J., Peter F. Buckley, and Fiona P. Gaughran. Effects of antipsychotic medications on physical health. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198811688.003.0006.

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Antipsychotic medications are a crucial part of the core platform upon which effective treatments for schizophrenia are built. While the marketed agents have established efficacy for reduction in the symptoms of schizophrenia, they all carry some side effects. Such effects differ across medications and between individuals. Prescribers need to be aware of the side effect profile of the medications they use, and ensure patients are also aware, so that a true shared decision-making model can be followed in terms of medication choice. Appreciation of long-term risk is required, with treatment choice in the short term having a view to the long term.

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Lam, Raymond W. Somatic treatments. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199692736.003.0008.

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• Wake therapy, exercise and light therapy are non-invasive and clinically useful treatments.• Electroconvulsive therapy remains an effective, safe and well-tolerated treatment for patients with severe, psychotic or medication-resistant depression.• Repetitive transcranial magnetic stimulation is an emerging treatment with evidence for acute efficacy, but with limited data about long-term management....

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Hoffman, Ralph E., and Arielle D. Stanford. TMS clinical trials involving patients with schizophrenia. Edited by Charles M. Epstein, Eric M. Wassermann, and Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0042.

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Repetitive transcranial magnetic stimulation ((r)TMS) is being studied as an experimental intervention for patients with neuropsychiatric disorders. These approaches have been informed by animal studies of long-term potentiation (LTP) and long-term depression (LTD). They show that repeated stimulation of neural circuits could exert effects on synaptic efficacy, for varying amounts of time, beyond the period of stimulation. Few studies using rTMS as a potential clinical intervention for schizophrenia have been carried out. They show promise in terms of advancing the understanding of pathophysiological mechanisms and developing alternative interventions. These studies, considered together, suggest that rTMS holds promise as an intervention strategy for patients with schizophrenia. Rigorously designed trials with larger numbers of subjects are indicated in order to take into account nonspecific factors that could add noise to outcome data.

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Valeriano, Brandon. Introduction. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190618094.003.0001.

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This chapter evaluates the efficacy of modern cyber strategies and how states coerce rivals in the digital domain. It argues that these campaigns are neither as revolutionary nor as novel as they seem. It finds that cyber disruptions, short-term and long-term espionage, and degradation operations all usually fail to produce concessions. When states do compel a rival, which is measured as a change in behavior in the target that is strategically advantageous to the initiator, the cyber operation tends to occur alongside more traditional coercive instruments such as diplomatic pressure, economic sanctions, and military threats and displays. Cyber capabilities complement, but do not replace traditional statecraft. Theoretical and empirical investigation of cyber strategies and their efficacy should therefore precede development of suggestions for sound foreign policy responses to state-backed cyber intrusions or craft international frameworks that constrain the proliferation of politically motivated malware. This book is a critical first step.

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Chan, Jonathan, and Nigil Haroon. Treatment: NSAIDs. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198734444.003.0020.

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Non-steroidal anti-inflammatory drugs (NSAIDs) constitute a diverse group of medications that inhibit prostaglandin synthesis. NSAIDs form the first-line pharmacological therapy in ankylosing spondylitis (AS). A number of randomized controlled trials (RCTs) support the efficacy of NSAIDs in reducing pain and improving patient function. Head-to-head comparisons have demonstrated equivalent effect of different NSAIDs in symptom control. The proposed disease-modifying potential of regular NSAID therapy is debatable and recent literature provides evidence to the contrary. Several safety concerns have been raised regarding long-term use of NSAIDs, especially an increase in cardiovascular risk. This chapter discusses the pharmacology, efficacy in treatment of AS, disease-modifying potential, and safety concerns of NSAIDs.

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Kass, Erica, Jonathan E. Posner, and Laurence L. Greenhill. Pharmacological Treatments for Attention-Deficit/Hyperactivity Disorder and Disruptive Behavior Disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0004.

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Abstract (sommario):

More than 225 placebo-controlled type 1 investigations demonstrate that psychostimulants are highly effective in reducing core symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and adults. In contrast, there are limited type I studies demonstrating that psychopharmacological management with U.S. Food & Drug Administration-approved agents for ADHD (stimulants and nonstimulants), atypical antipsychotics, and mood stabilizers decrease the defiant and aggressive behavior characteristic of disruptive behavior disorders. Stimulant treatment evidence has been supplemented by two large multisite randomized controlled trials. Randomized controlled trials from the past 15 years continue to report several key adverse events associated with stimulants but have not supported rarer and more serious problems. Although psychostimulants have been shown to retain their efficacy for as long as 14 months, their long-term academic and social benefits are not as robust. Nonstimulant agents for which there is more limited evidence of efficacy include atomoxetine, alpha-agonists, modafinil, and bupropion.

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Davidson, Judy E., and Giora Netzer. Family Response to Critical Illness. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199398690.003.0008.

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Abstract (sommario):

Family members of ICU patients can have mental, physical, and social responses to critical illness. These responses can begin when their loved ones are in the ICU and persist after discharge. Interventions in the ICU could have long-term effects on family members. Communication, proximity, engagement, maintaining family integrity, optimizing sleep, and conflict resolution may all play a role in family health following the discharge or death of the patient. Research is needed to further quantify the epidemiology, mechanisms of action, and efficacy of interventions to optimize the health of this large group of people. While waiting for research results to definitively point us towards effective preventive measures and early interventions, it is prudent to optimize communication, encourage proximity and engagement, and support the health of family members while caring for the critically ill and injured. As patients and their families move into the home environment, it is important to consider their long-term health as well.

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