Letteratura scientifica selezionata sul tema "Lipid-related disorders"
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Articoli di riviste sul tema "Lipid-related disorders":
Wu, Xunzhi, Zhen Chen, Yue Wu, Yifan Chen, Jiaping Jia, Nianqiu Shen, Hitoshi Chiba e Shu-Ping Hui. "Flazin as a Lipid Droplet Regulator against Lipid Disorders". Nutrients 14, n. 7 (3 aprile 2022): 1501. http://dx.doi.org/10.3390/nu14071501.
Kleme, Marie-Laure, e Emile Levy. "Cystic Fibrosis-Related Oxidative Stress and Intestinal Lipid Disorders". Antioxidants & Redox Signaling 22, n. 7 (marzo 2015): 614–31. http://dx.doi.org/10.1089/ars.2014.6012.
Wang, Jiayi, Jinzhong Jing, Zhengyi Gong, Jiayong Tang, Longqiong Wang, Gang Jia, Guangmang Liu et al. "Different Dietary Sources of Selenium Alleviate Hepatic Lipid Metabolism Disorder of Heat-Stressed Broilers by Relieving Endoplasmic Reticulum Stress". International Journal of Molecular Sciences 24, n. 20 (22 ottobre 2023): 15443. http://dx.doi.org/10.3390/ijms242015443.
Di, Sha, Yitian Wang, Lin Han, Qi Bao, Zezheng Gao, Qing Wang, Yingying Yang, Linhua Zhao e Xiaolin Tong. "The Intervention Effect of Traditional Chinese Medicine on the Intestinal Flora and Its Metabolites in Glycolipid Metabolic Disorders". Evidence-Based Complementary and Alternative Medicine 2019 (4 giugno 2019): 1–13. http://dx.doi.org/10.1155/2019/2958920.
Beaufrère, Hugues, Drury Reavill, Jill Heatley e Leonardo Susta. "Lipid-Related Lesions in Quaker Parrots (Myiopsitta monachus)". Veterinary Pathology 56, n. 2 (24 settembre 2018): 282–88. http://dx.doi.org/10.1177/0300985818800025.
Latruffe, Norbert. "Insights on recent advances in lipid metabolism and related disorders". Biochimie 86, n. 11 (novembre 2004): 741–42. http://dx.doi.org/10.1016/j.biochi.2004.10.001.
Grummer, Ric R. "Etiology of Lipid-Related Metabolic Disorders in Periparturient Dairy Cows". Journal of Dairy Science 76, n. 12 (dicembre 1993): 3882–96. http://dx.doi.org/10.3168/jds.s0022-0302(93)77729-2.
Wan, Juan, Meiyan Feng, Wenjing Pan, Xin Zheng, Xinya Xie, Baozhu Hu, Cuiqin Teng et al. "Inhibitory Effects of Six Types of Tea on Aging and High-Fat Diet-Related Amyloid Formation Activities". Antioxidants 10, n. 10 (24 settembre 2021): 1513. http://dx.doi.org/10.3390/antiox10101513.
Vučević, Danijela, Drago Đorđević, Marija Stanojević, Bojan Jorgačević, Danka Đorović, Đorđe Radak e Tatjana Radosavljević. "Hypercholesterolemias: Pathogenesis and pathophysiological implications". Medicinska istrazivanja 50, n. 2 (2016): 30–43. http://dx.doi.org/10.5937/medist1602030v.
Belamarich, Peter F. "Lipoprotein Disorders". Pediatrics In Review 17, n. 4 (1 aprile 1996): 144. http://dx.doi.org/10.1542/pir.17.4.144.
Tesi sul tema "Lipid-related disorders":
Kuznetcova, Daria. "Development and characterization of chia (Salvia hispanica L.) plant-derived products as natural bioactive compounds". Electronic Thesis or Diss., Université de Lorraine, 2020. http://www.theses.fr/2020LORR0266.
Omega-3 polyunsaturated fatty acids (PUFA) are important for nutrition and health, by virtue of their importance in lipid homeostasis, and the fact that PUFA deficiencies can increase risk of metabolic syndrome, cardiovascular and neurodegenerative diseases. Chia (Salvia hispanica L.) seeds are rich in PUFA (80%) and contain the highest known levels in plants of the essential omega-3 fatty acid, alpha-linolenic acid (ALA). High degree of unsaturation in edible oils can reduce oxidative stability causing a loss of nutritional value. Nanotechnology can be used to improve chia seed oil quality and safety, increase bioavailability, and expand the scope of applications. Towards this goal, our objective was to prepare and characterize chia seed lipids in the form of nanoliposomes (NL) and nanoemulsions (NE), and to evaluate their potential use as bioactive products. The first step was to characterize lipid fractions. Lipids were extracted from the French ORURO variety of chia seeds using modified Folch method. Ten fatty acid species and six phospholipid (PL) classes were identified in chia seed lipid extract by gas chromatography and LC-MS, respectively, with the highest level of fatty acids being ALA (62%). The presence of a solid residue was detected following evaporation of the solvent to obtain chia seed oil. Analyses by thin layer chromatography and LC-MS demonstrated that this residue contained the polar lipids including PL that were no longer in the chia oil after removal of solvent by evaporation. NE were prepared from chia seed oil and the chia PL-rich solid residue, and NL from the PL-rich solid residue. Physicochemical characterization including analysis of the polydispersity index (PDI), size, and zeta-potential indicated that both NE and NL were monodispersed solutions of stable (low negative zeta potential) particles with a size between 104-118 nm. These preparations were spherical and multilayered (transmission electron microscopy) and remained stable even 5 days after preparation. In addition, enzymatic assay confirmed PL content in both NE and NL. MTT cell viability assay showed little to no cell toxicity (up to 150 µg/mL NE or NL) following 24 h incubation with cultured hepatocytes, neurons, and astrocytes. In conclusion, these results demonstrate the feasibility of using chia lipids for the preparation of stable non-toxic omega-3 PUFA rich NL and NE, which represent potential bioactive vectors for both preventive and therapeutic applications in human health
Martins, Susana Isabel Vargas. "New insights into biological effects of conjugated linoleic acid and saturated fats in body fat composition, obesity and related disorders: experimental studies in normal-weight Wistar and obese Zucker rats". Doctoral thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2010. http://hdl.handle.net/10400.5/1770.
The daily intake of conjugated linoleic acid (CLA) isomers by humans, through diet and supplementation, and the controversial effects of these compounds in human health, were the main motivation for the elaboration of this thesis. Firstly, the present work intended to estimate the daily CLA ingestion by the Portuguese population. Secondly, the biological effects of CLA were exploited using two distinct animal models, normal-weight (Wistar rat) and genetically fat (obese Zucker rat), in combination with saturated fat based diets. The estimative of total CLA intake for the Portuguese population was 73.70 mg/day. The cis(c)9,trans(t)11 and t7,c9 were the most prevalent CLA isomers, with, respectively, 76.10 and 12.56% of the total CLA intake value. Concerning the animal trials, CLA in conjugation with saturated fats revealed beneficial but also deleterious biological effects. In the normal-weight Wistar rat fed a palm oil based diet, the administration of c9,t11 CLA isomer increased the serum triacylglycerols and the size of adipocytes from epididymal and retroperitoneal fat depots. In addition, a CLA mixture of c9,t11 and t10,c12 isomers increased the glycerol membrane permeability of kidney proximal tubules, which may indicate an improvement of glycerol reabsorption pathway. In the obese Zucker rat, CLA (as a mixture) induced changes in fatty acid profile of liver, muscle and adipose depots. CLA supplemented with a vegetable saturated fat diet seemed to promote a more beneficial adipokine serum profile and an alleviation of hepatic steatosis. In contrast, adverse effects of CLA were observed with hypercholesterolaemia promotion. Regardless CLA, the ovine fat diets worsened the insulin resistance and increased the pro-inflammatory serum cytokines. In the liver, different levels of cell death and apoptotic pathways were modulated by CLA, depending on the type of saturated fat present in the diet. The most striking result of this study was that CLA was not able to promote fat loss in both experimental models. Moreover, new mechanisms of CLA action were disclosed in this work, which reinforce the need to further investigate this compound.
RESUMO - Efeitos biológicos do ácido linoleico conjugado e de gorduras saturadas na composição da gordura corporal, na obesidade e patologias associadas: estudos experimentais em ratos Wistar e Zucker obesos - A ingestão diária de isómeros do ácido linoleico conjugado (CLA), através da dieta e da sua suplementação, bem como, os efeitos controversos destes compostos na saúde humana, constituíram a principal motivação para a elaboração desta tese. Numa primeira fase, o trabalho pretendeu estimar a ingestão diária de CLA pela população Portuguesa. Posteriormente, foram avaliados os efeitos biológicos do CLA quando suplementado a dietas à base de gordura saturada. Para tal, recorreu-se a dois modelos animais distintos, o rato Wistar e o rato Zucker (geneticamente obeso). A ingestão média total de CLA pela população Portuguesa foi estimada em 73.70 mg/dia. Os isómeros do CLA mais representativos foram o cis(c)9,trans(t)11 e o t7,c9, correspondendo, respectivamente, a 76.10 e 12.56% do total de CLA ingerido. Quanto aos estudos in vivo, o CLA revelou efeitos biológicos tanto benéficos como prejudiciais. No modelo Wistar alimentado com dieta à base de óleo de palma, a administração do isómero do CLA c9,t11 elevou os níveis de triacilgliceróis no soro, bem como, o tamanho dos adipócitos das gorduras epididimal e retroperitoneal. Adicionalmente, a mistura de isómeros do CLA (c9,t11 e t10,c12) aumentou a permeabilidade membranar ao glicerol no túbulo proximal do rim, sugerindo uma melhoria no processo de reabsorção desta molécula. No modelo Zucker, o CLA (como mistura de isómeros) induziu alterações no perfil dos ácidos gordos do fígado, músculo e gorduras epididimal e retroperitoneal. O CLA administrado com óleo de palma promoveu um perfil de adipocinas no soro mais benéfico e melhorou a esteatose hepática. Em contraste, a suplementação com CLA apresentou um efeito hipercolesterolémico. Independentemente do CLA, a dieta rica em gordura de ovinos agravou a resistência à insulina e aumentou as adipocinas pró-inflamatórias no soro. No fígado, diferentes níveis de morte celular e vias apoptóticas foram modeladas pelo CLA em função do tipo de gordura presente na dieta. É de salientar que não se observaram efeitos anti-adipogénicos do CLA em nenhum dos dois modelos animais. Por último, esta tese contribuiu para a descoberta de novos mecanismos de acção dos isómeros do CLA, reforçando a necessidade de continuar a estudar estes compostos.
This work was funded by Fundação para a Ciência e a Tecnologia (FCT) through the individual fellowship SFRH/BD/22566/2006 and co-financed by the grant POCTI/44750/2002
Libri sul tema "Lipid-related disorders":
Evert, Alison B., e Marion J. Franz. American Diabetes Association guide to medical nutrition therapy for diabetes. 2a ed. Alexandria, Va: American Diabetes Association, 2012.
Jardine, Alan G., e Rajan K. Patel. Lipid disorders of patients with chronic kidney disease. A cura di David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0102.
Sills, Irene N., e Martin M. Fisher, a cura di. AM:STARs: Advances in the Treatment of Endocrine Disorders in Adolescents, Vol. 26, No. 2. American Academy of Pediatrics, 2015. http://dx.doi.org/10.1542/9781581109498.
American Diabetes Association guide to medical nutrition therapy for diabetes. Alexandria, Va: American Diabetes Association, 1999.
Association, American Diabetes. American Diabetes Association Guide to Medical Nutrition Therapy for Diabetes (Clinical Education Series). American Diabetes Association, 2003.
Capitoli di libri sul tema "Lipid-related disorders":
Noah, Kelly, e Elaine Tierney. "Lipid-Related Pathophysiology of ASD". In Neurobiology of Autism Spectrum Disorders, 145–66. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42383-3_8.
Abouakil, Nehza, Ewa Rogalska e Dominique Lombardo. "One Step Purification of Pancreatic Cholesterol Ester Hydrolase: Application to the Related Enzyme of Human Milk". In Lipid Storage Disorders, 539–43. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1029-7_67.
Bogaievsky, Y., F. Torossian, G. Jost e F. Bonnefous. "Clinical Effect of Lipanthyl on Tinnitus Aurium and Other Symptoms Related to Inner Ear Disorders". In Drugs Affecting Lipid Metabolism, 343–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71702-4_64.
Taguchi, Ryo, Kazutaka Ikeda e Hiroki Nakanishi. "Lipidomics for Elucidation of Metabolic Syndrome and Related Lipid Metabolic Disorder". In Lipidomics, 233–50. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527655946.ch12.
Suksangrat, Tanapa, Phatchariya Phannasil e Sarawut Jitrapakdee. "miRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-alcoholic Fatty Liver Disease". In Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders, 129–48. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-12668-1_7.
"Lipid Peroxidation and Age-Related Neurodegenerative Disorders". In Lipid Oxidation in Health and Disease, 350–83. CRC Press, 2015. http://dx.doi.org/10.1201/b18138-21.
Dubowitz, Victor, e Caroline A. Sewry. "Metabolic myopathies II: Lipid related disorders and mitochondrial myopathies". In Muscle Biopsy, 469–92. Elsevier, 2007. http://dx.doi.org/10.1016/b978-1-4160-2593-1.50023-1.
Shilpi, Satish, Ashish Jain, Sonal Dixit, Gaurav Saraogi, Awesh K. Yadav e Sanjay K. Jain. "Lipid nanocarrier-based drug delivery for the treatment of brain-related disorders". In Nanomedical Drug Delivery for Neurodegenerative Diseases, 55–65. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-323-85544-0.00014-9.
Harun, Harnavi. "Lipid Peroxidation: Aging Kidney". In Lipid Peroxidation [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95801.
Hafeez, Abdul, e Shazia Afzal Usmani. "Perspective Chapter: Nose-to-Brain Drug Delivery through Liposomes - Recent Applications". In Liposomes - Recent Advances, New Perspectives and Applications. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.106374.
Atti di convegni sul tema "Lipid-related disorders":
Kaya Bingöl, Züleyha, Gulseren Sagcan, Hacer Durmus Tekce, Piraye Serdaroglu e Esen Kiyan. "Pulmonary functions and sleep related breathing disorders in lipid storage disease". In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.oa4842.
Glanao, Jean-Marie, e Thierry Durand. "The wonders of isoprostanoids in biological systems". In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/mwci6999.
Ahmed, Amira, Huda Farah, Omnia Ahmed, Dina Elsayegh, Abdelrahman Elgamal e Nasser Moustafa Rizk. "Profile Of Oxidative Stress Genes In Response To Obesity Treatment". In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0150.
Rapporti di organizzazioni sul tema "Lipid-related disorders":
LI, Peng, e Junjun Liu. Effect of statin therapy on moderate-to-severe depression: an updated systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, marzo 2022. http://dx.doi.org/10.37766/inplasy2022.3.0016.