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1
Turov, Kostyantyn. "Anticancer evaluation of di- and trifunctional substituted 1,3-thiazoles". Ukr. Bioorg. Acta 2020, Vol. 15, N1 15, n. 1 (30 giugno 2020): 2–11. http://dx.doi.org/10.15407/bioorganica2020.01.002.
Testo completoAbstract (sommario):
Anticancer activity of a series of polyfunctional substituted 1,3-thiazoles has been studied within the international scientific program “NCI-60 Human Tumor Cell Lines Screen”. Screening was performed in vitro on 60 cell lines of lungs, kidneys, CNS, ovaries, prostate, and breast cancer, epithelial cancer, leukemia, and melanoma. The most effective compounds were those with a piperazine substituent at C2 of the 1,3-thiazole cycle: 1-(4-((4-methylphenyl)-sulfonyl)-2-phenyl-1,3-thiazol-5-yl)piperazine (average lg GI50 = -5.87, lg TGI = -5.54, lg LC50 = -5.21), 1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-((4-methylpheyl)sulfonyl)-1,3-thiazol-5-yl)piperazine (average lg GI50 = -5.66, lg TGI = -5.26, lg LC50 = -4.83), and 1-(2,4-bis((4-methylphenyl)sulfonyl)-1,3-thiazol-5-yl)piperazine (average lg GI50 = -5.67, lg TGI = -5.21, lg LC5050 = -4.67).
2
Reinisch, August. "International Centre for Settlement of Investment Disputes (ICSID): LG&E Energy Corp., LG&E Capital Corp., LG&E International Inc. v. the Argentine Republic". International Legal Materials 46, n. 1 (gennaio 2007): 36–76. http://dx.doi.org/10.1017/s0020782900006148.
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WAIBEL, MICHAEL. "Two Worlds of Necessity in ICSID Arbitration: CMS and LG&E". Leiden Journal of International Law 20, n. 3 (30 agosto 2007): 637–48. http://dx.doi.org/10.1017/s0922156507004293.
Testo completoAbstract (sommario):
Two recent ICSID cases, CMS v. Argentina and LG&E v. Argentina, diverge on the application of necessity under customary international law. The LG&E tribunal affirmed that Argentina's financial crisis amounted to a state of necessity. On virtually identical facts, CMS had reached the opposite conclusion 18 months earlier. This unhealthy split of opinion highlights the fact that necessity is ill-suited to financial crises. The state of necessity is at best a crude defence, appropriate as long as international law in this area remains underdeveloped. Lack of payment capacity will strike a better balance between host country and investor interests in future sovereign debt crises. This defence is also more amenable to adjudication by national courts and international tribunals.
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Potikha, Lyudmyla, Volodymyr Brovarets e Victor Zhirnov. "Biological Evaluation of 3-Aminoisoquinolin-1(2H)-one Derivatives as Potential Anticancer Agents Authors Lyudmyla Potikha". French-Ukrainian Journal of Chemistry 9, n. 2 (2021): 52–63. http://dx.doi.org/10.17721/fujcv9i2p52-63.
Testo completoAbstract (sommario):
Anticancer activity of a series of 3-(hetaryl/aryl)amino substituted isoquinolin-1(2H)-ones has been studied within the international scientific program “NCI-60 Human Tumor Cell Lines Screen”. Screening was performed in vitro on 60 cell lines of lungs, kidneys, CNS, ovaries, prostate, and breast cancer, epithelial cancer, leukemia, and melanoma. The most effective compounds were those with thiazolyl or pyrazolyl substituent at 3-amino group and had no substituents at C(4) of the isoquinoline cycle. We identified a new lead compound, 3-(1,3-thiazol-2-ylamino)isoquinolin-1(2H)-one 12, which effectively prevents tumor cell growth (average lg GI50 = -5.18, lg TGI = -4.1, lg LC50 > -4.0) with good selectivity.
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Levieux, Didier, e Annie Venien. "Rapid, sensitive two-site ELISA for detection of cows' milk in goats' or ewes' milk using monoclonal antibodies". Journal of Dairy Research 61, n. 1 (febbraio 1994): 91–99. http://dx.doi.org/10.1017/s0022029900028089.
Testo completoAbstract (sommario):
SummaryA sandwich ELISA (enzyme-linked immunosorbent assay) of the two-site type has been successfully developed for the detection of cows' milk in goats' or ewes' milk. The assay uses two monoclonal antibodies (MAb) raised in mice against cows' β-lactoglobulin (β-lg). These MAb recognize different epitopes of the β-lg, which are sufficiently distinct to allow simultaneous binding of the corresponding antibodies. One of the MAb recognizes a species-specific epitope of the bovine β-lg and was adsorbed to a plastic microtitration plate (capture antibody). The second MAb was labelled with peroxidase and used to detect the captured cows' β-lg. Factors affecting assay performance were investigated. The optimized assay is highly specific, reproducible (intra- and inter-assay CV were 8 and 13% respectively) and sensitive: as little as 5 ng β-lg/ml or 1 part cows' milk per 100000 parts goats' or ewes' milk can be detected. The technique is robust, cheap, rapid, reliable and suitable for high sample throughput, semi-automation and screening surveys. The MAb used guarantee the high specificity of the assay and indefinite reagent supply of constant quality once approved by collaborative national or international trials.
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Rezal Rasli, Mohd, Halimah Abdul Manaf e Mazlan Ismail. "Examining the integrity behavior challenges of enforcement officers in Malaysian local government". Problems and Perspectives in Management 18, n. 1 (19 marzo 2020): 263–77. http://dx.doi.org/10.21511/ppm.18(1).2020.23.
Testo completoAbstract (sommario):
There is a call from society to examine the integrity behavior challenges of local government (LG) enforcement officers who work directly with citizens due to the nature of this job. One of the job requirements of enforcement officers is to investigate law enforcement directly to their customers, such as petty traders, hawkers, business owners, developers and contractors, and others. In executing their duties, particularly on law enforcement, high integrity behavior and professionalism of enforcement officers in LG administrative areas of responsibility are necessary. Based on the framework, the study aims to examine the integrity behavior challenges of enforcement officers from the citizens’ and staff’ perspectives, in particular, on to what extent the officers face the difficulties and challenges in executing their enforcement tasks. Thus, during the study, 30 respondents, namely the citizens and LG staff in Kedah, were surveyed. The data were analyzed using thematic analysis to gain specific dimensions related to integrity behavior. From the citizens’ perspective on LG enforcement teams’ integrity behavior, challenges were related to main aspects such as biasness, political intervention, and bureaucracy matters. Meanwhile, LG staff consider integrity behavior challenges to be affected by opportunistic attitudes among staff, workforce, and financial issues. The study suggests that enforcement officers should develop soft skills, employability skills, and upgrade academic levels to understand the current situation and develop negotiation skills to deal with grassroots society.
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Roy, Snigdha, Dinesh Chandra Roy, Md Mahmud Al Noor, Shampa Rani Ghosh, Farid Ahmed e Deboprio Roy Sushmoy. "Binamasur-10, the first drought tolerant lentil variety registered in Bangladesh". Research in Agriculture Livestock and Fisheries 6, n. 2 (9 settembre 2019): 253–62. http://dx.doi.org/10.3329/ralf.v6i2.43048.
Testo completoAbstract (sommario):
from International Centre for Agricultural Research in the Dry Areas (ICARDA) including some advanced lines from Bangladesh Institute of Nuclear Agriculture in 2006. During Preliminary Yield Trial, the genotype LG-208 produced 18.62% and 29.47% higher seed yield than the check variety BARI Masur-5 at Ishurdi and Magura respectively. Through advanced yield trials, regional yield trials, on-station and on-farm trials from 2010-11 to 2015-16, it was found that exotic germplasm LG-208 showed better performance than check (BARI Masur-5). Genotype LG-208 had significantly highest seed setting and harvest index under 20% polyethylene glycol (PEG) induced drought and considered as the drought tolerant which showed similar performance with field trials in drought-prone areas (Chapainawabganj and Rajshahi). Based on the superior performance of exotic germplasm LG-208 line, BINA has decided with the National Seed Board (NSB) of Bangladesh to register this line as a high yielding drought tolerant lentil variety, named as Binamasur-10 in 2016.
Res. Agric., Livest. Fish.6(2): 253-262, August 2019
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Frutos-Peterson, C. "LG&E Energy Corp., LG&E Capital Corp. and LG&E International Inc. v. Argentine Republic (ICSID Case No. ARB/02/1): Introductory Note". ICSID Review 21, n. 1 (1 marzo 2006): 150–54. http://dx.doi.org/10.1093/icsidreview/21.1.150.
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Miyamoto, Hiroshi, Fadi Brimo, Luciana Schultz, Huihui Ye, Jeremy S. Miller, Daniel A. Fajardo, Thomas K. Lee, Jonathan I. Epstein e George J. Netto. "Low-Grade Papillary Urothelial Carcinoma of the Urinary Bladder: A Clinicopathologic Analysis of a Post–World Health Organization/International Society of Urological Pathology Classification Cohort From a Single Academic Center". Archives of Pathology & Laboratory Medicine 134, n. 8 (1 agosto 2010): 1160–63. http://dx.doi.org/10.5858/2009-0403-oa.1.
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Abstract Context.—Few large cohort studies have addressed outcome in patients with noninvasive low-grade papillary urothelial carcinoma (LG-UrCa) following implementation of the 2004 World Health Organization/International Society of Urological Pathology (WHO/ISUP) consensus classification. Objective.—To evaluate our cohort of LG-UrCa cases classified according to 2004 WHO/ISUP to reassess outcome and interobserver agreement. Design.—Files were searched for all patients diagnosed with LG-UrCa between 1998 and 2008. All sections were reevaluated for accuracy of classification. Results.—A total of 112 cases initially diagnosed as LG-UrCa were identified. Of those, 8 of 55 cases (15%) initially diagnosed by nonurologic pathologists were reclassified as high-grade papillary urothelial carcinoma and were excluded. The mean length of follow-up was 40.1 months (range, 2–113 months). Tumor recurrence was encountered in 56 of 104 patients (53.8%), including 37 (35.6%) with LG-UrCa or lower-grade tumors and 19 (18.3%) with high-grade papillary urothelial carcinoma. Of the 19 patients demonstrating grade progression, 7 (37%) also developed stage progression (invasive carcinoma, n = 5; metastatic carcinoma, n = 2). Seven patients eventually underwent radical cystectomy. None of the 104 patients died of bladder cancer. The mean number of recurrence episodes was 3.11. The mean durations of time to first recurrence and time to grade progression were 13.9 months and 25.1 months, respectively. The mean size of initial tumors was 1.73 cm. There was no significant correlation between tumor size, patient age, sex, or smoking history and the likelihood for recurrence or grade progression. A significantly higher rate of recurrence was seen in patients with multiple tumors at initial diagnosis (P = .04). Conclusions.—A tendency to underdiagnose high-grade papillary urothelial carcinoma continues to exist. More than half (53.8%) of patients with LG-UrCa developed recurrence, with an 18.3% incidence of grade progression and a 6.7% incidence of stage progression. Patients with multiple initial tumors had significantly higher risk of developing recurrence.
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Schill, Stephan W. "International Investment Law and the Host State’s Power to Handle Economic Crises – Comment on the ICSID Decision in LG&E v. Argentina ". Journal of International Arbitration 24, Issue 3 (1 giugno 2007): 265–86. http://dx.doi.org/10.54648/joia2007019.
Testo completoAbstract (sommario):
Argentina is facing several claims under bilateral investment treaties (BITs) relating to its emergency legislation passed to tackle its economic crisis in 2001–2002. This article critically analyzes the second ICSID decision on the merits handed down in this context in LG&E Energy Corp. v. Argentina and compares it to the earlier award in CMS v. Argentina. While the decisions do not differ substantially as to the interpretation of substantive investment law, they diverge significantly on the concept of necessity. Unlike CMS, LG&E in part accepted Argentina’s plea of necessity. The article argues that the award in LG&E misconstrued the burden of proof for limiting elements of necessity, such as the question of Argentina’s contribution to the crisis and the selection of less restrictive means, and questions whether its exclusion of compensation for the investor’s material loss was accurate even if the plea of necessity was operative.
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Bhatt, P. R. "Market innovative Strategy a Case of LG Electronics". Vision: The Journal of Business Perspective 7, n. 2 (luglio 2003): 87–96. http://dx.doi.org/10.1177/097226290300700207.
Testo completoAbstract (sommario):
LG Electronics (LGE) is the third in the rank of three largest chaebols after Hyundai and Samsung in South Korea. LGE has got more than 70 subsidiaries in 40 countries. The thrust of LGE was on home appliances, PC related multimedia products, electronic products and telecommunication products such as handsets, mobile systems and network system. LGE aimed at attaining top position in digital TV and telecommunication equipments in the world. It also aimed at strengthening its core competency as ‘Digital Leader’ in electronic products and equipment in this digital era. Bon Moo Koo, after taking over as Chairman of LG group in 1995, has adopted “Leap 2005” as the basic philosophy of LGE group. According to the principle of “Leap 2005”, LG group was to grow from around US $38 billion in 1994 to US $380 billion by 2005 with 50% coming from international sales. LGE has adopted a differentiation strategy to concentrate on the high end of the entire products segment it enters. It cultivated an image for both technology and quality. Globalisation and innovation were the major strategies of LGE through mergers, acquisitions, divestures and alliances.
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Arnold, Michael A., R. Daniel Lineberger, Tim D. Davis, David W. Reed e William J. McKinley. "A Survey of North American Horticulture Graduate Programs: Demographics, Policies, Finances, and Metrics". HortTechnology 24, n. 2 (aprile 2014): 241–51. http://dx.doi.org/10.21273/horttech.24.2.241.
Testo completoAbstract (sommario):
A comprehensive survey of American and Canadian universities that offer masters, doctoral, or both degrees in horticulture resulted in responses from 27 academic units. Units were surveyed regarding types of degrees offered, admissions policies, demographic characteristics of students, financial assistance provided to students, faculty ranks and salaries, and metrics by which the programs were evaluated by university administration. About 80% of the programs resided in 1862 Morrill Act land-grant institutions (LG) with the remainder housed in other non-land-grant institutions (NLG). Thirty-eight percent of reporting LG programs existed as stand-alone horticulture departments, whereas horticulture programs were combined with other disciplines in the remainder. Admissions criteria were most consistent among LG programs. Participation in distance education programs was low, but growing. Financial support of graduate students was more common in LG programs. Most schools offered some sort of tuition reduction to those students on assistantships/fellowships and offered health insurance options. Payment of fees was rare and the level of stipends provided varied substantially among programs. International student enrollment was greatest at LG programs and had remained steady in recent years. Gender equity was present among graduate students, with nearly equal male and female enrollment. Most graduate students at both LG (63.6%) and NLG (75.0%) programs were non-Hispanic White; although overall minority enrollment had increased but was still not similar in distribution to that of the general U.S. population. Professors (46.7%) and Associate Professors (28.3%) dominated the faculty ranks while Assistant Professors (19.3%) and lecturers/instructors (5.7%) constituted a much smaller portion of the faculty. Faculty salaries varied tremendously among institutions, especially for senior faculty. Female and ethnic minorities were underrepresented in faculty ranks compared with the general U.S. population. Aside from total graduate program enrollment, the relative importance of various evaluation metrics for programs was highly variable among institutions. Data discussed herein should be useful to universities with horticulture graduate programs for peer institution comparisons during program assessments, accreditation reviews, or for strategic planning purposes.
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Reinig, Frederick, Adam Sookdeo, Jan Esper, Michael Friedrich, Giulia Guidobaldi, Gerhard Helle, Bernd Kromer et al. "Illuminating Intcal During the Younger Dryas". Radiocarbon 62, n. 4 (24 aprile 2020): 883–89. http://dx.doi.org/10.1017/rdc.2020.15.
Testo completoAbstract (sommario):
ABSTRACTAs the worldwide standard for radiocarbon (14C) dating over the past ca. 50,000 years, the International Calibration Curve (IntCal) is continuously improving towards higher resolution and replication. Tree-ring-based 14C measurements provide absolute dating throughout most of the Holocene, although high-precision data are limited for the Younger Dryas interval and farther back in time. Here, we describe the dendrochronological characteristics of 1448 new 14C dates, between ~11,950 and 13,160 cal BP, from 13 pines that were growing in Switzerland. Significantly enhancing the ongoing IntCal update (IntCal20), this Late Glacial (LG) compilation contains more annually precise 14C dates than any other contribution during any other period of time. Thus, our results now provide unique geochronological dating into the Younger Dryas, a pivotal period of climate and environmental change at the transition from LG into Early Holocene conditions.
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Haustein, Ellen, Peter C. Lorson, Lasse Olavi Oulasvirta e Lotta-Maria Sinervo. "Perceived usability of local government (LG) financial statements by local councillors: comparative study of Finland and Germany". International Journal of Public Sector Management 34, n. 4 (3 giugno 2021): 441–58. http://dx.doi.org/10.1108/ijpsm-09-2020-0227.
Testo completoAbstract (sommario):
PurposeThis paper studies the usability of LG financial statements as perceived by local councillors. By drawing on a comparative view of two countries with different periods of accrual accounting use in the public sector, the authors investigate how local councillors assess the usability of LG financial statements in order to question accounting reform success. Determinants that influence the usability assessment are explored.Design/methodology/approachExploratory design: data were collected from questionnaires with 24 local councillors from five Finnish local governments (LGs) and 30 local councillors from six German LGs. An adjusted variant of the system usability scale was analysed with descriptive statistics and non-parametric group comparisons.FindingsIn both countries, the usability assessment of financial statements seems to be positive, indicating a successful reform process. In Finland, where the accrual government accounting reform has had a longer time to settle in, councillors seem to assess usability only partially better than German councillors. Several determinants of the usability assessment were detected, such as size and debt level of the LG as well as local councillors' gender, political orientation and education. Generally, councillors need more assistance and training in using financial statements.Originality/valueThe study is the first to conduct a quantitative assessment of the usability of LG financial statements as perceived by councillors. The system usability scale was adjusted to a public sector reporting context. The paper adopts a transnational comparative approach.
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Chen, Zhilin, Xingyi Tan, Qiang Li, Jing Wan e Gang Xu. "High-Performance One-Dimensional Sub-5 nm Transistors Based on Poly(p-phenylene ethynylene) Molecular Wires". Molecules 29, n. 13 (5 luglio 2024): 3207. http://dx.doi.org/10.3390/molecules29133207.
Testo completoAbstract (sommario):
Poly(p-phenylene ethynylene) (PPE) molecular wires are one-dimensional materials with distinctive properties and can be applied in electronic devices. Here, the approach called first-principles quantum transport is utilized to investigate the PPE molecular wire field-effect transistor (FET) efficiency limit through the geometry of the gate-all-around (GAA) instrument. It is observed that the n-type GAA PPE molecular wire FETs with a suitable gate length (Lg= 5 nm) and underlap (UL = 1, 2, 3 nm) can gratify the on-state current (Ion), power dissipation (PDP), and delay period (τ) concerning the conditions in 2028 to achieve the higher performance (HP) request of the International Roadmap for Device and Systems (IRDS, 2022 version). In contrast, the p-type GAA PPE molecular wire FETs with Lg= 5, 3 nm, and UL of 1, 2, 3 nm could gratify the Ion, PDP, and τ concerning the 2028 needs to achieve the HP request of the IRDS in 2022, while Lg= 5 and UL = 3 nm could meet the Ion and τ concerning the 2028 needs to achieve the LP request of the IRDS in 2022. More importantly, this is the first one-dimensional carbon-based ambipolar FET. Therefore, the GAA PPE molecular wire FETs could be a latent choice to downscale Moore’s law to 3 nm.
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Christina, Tsao, Samir Dalia, Celeste M. Bello, Lubomir Sokol, Eduardo M. Sotomayor, Bijal D. Shah e Julio C. Chavez. "The Revised International Prognostic Index (R-IPI) Score Is Predictive Of Survival In Aggressive Transformed Lymphomas (TL) From Low Grade Non-Hodgkin Lymphomas In The Chemoimmunotherapy Era". Blood 122, n. 21 (15 novembre 2013): 4275. http://dx.doi.org/10.1182/blood.v122.21.4275.4275.
Testo completoAbstract (sommario):
Abstract Introduction Histologic transformation of low grade non Hodgkin lymphoma (LG-NHL) occurs with a variable frequency. Several factors have been associated with survival in transformed lymphoma (TL) and the prognosis has been generally poor. The R-IPI has been shown to be prognostic in the pre rituximab era. Purpose To assess R-IPI as prognostic at lymphoma transformation in the rituximab era. Methods Patients with a diagnosis of diffuse large B-cell lymphoma transformed from LG-NHL (DLBCL-TL) were identified between January 2001 and December 2011 through the Moffitt Cancer Center Total Cancer Care Database. LG-NHL included follicular lymphoma (FL), marginal zone lymphoma (MZL), mucosa associated tissue lymphoma (MALT) and other low grade histologies. Patients with small lymphocytic lymphoma (SLL) with Richter’s transformation were excluded. All patients received rituximab based chemotherapy at transformation. Clinical data, pathologic data include morphology and immunohistochemistry (IHC) including CD10, BCL6, MUM1/IRF4 were recorded. Overall survival (OS) was calculated from the date of transformation. OS was estimated by the Kaplan-Meier method and compared using the long-rank test. A p-value< 0.05 was considered statistically significant. Results A total of 81 patients were identified with DLBCL-TL. At diagnosis and transformation the median ages were 60 and 64 years (22 – 89), respectively. The male:female ratio was 0.72. The most common LG-NHL diagnosis was FL (75.3%). The median time to DLBCL transformation (TTT) was 3.4 years. At LG-NHL diagnosis 67.9% of patients were stage III/IV, 23.5% had bulky disease, 35.8% had extranodal disease (ED) and 14.8% were FLIPI1 score > 3. At transformation 29.6% had B symptoms, 77.8% had stage III/IV disease, 25.9% had ED, and 40.4% had an elevated LDH. DLBCL-GCB as per Hans algorithm was present in 65.5% of cases at transformation. The mean hemoglobin (Hb) and serum albumin (SA) level at transformation were 12.6 g/dl and 3.9 g/dl, respectively and an IPI > 3 was present in 22.2% of cases. R-IPI categories were very good in 4.9%, good in 72.8% and poor in 22.2%. Patients received rituximab prior to transformation in 65.4% with R-CHOP being the most common regimen used (84%). Radioimmunotherapy (RIT) was given in 17.3% of patients. Patients received 3 or more treatment lines in 74.1%. Patients underwent autologous and allogeneic stem cell transplant in 24.7 and 2.5% of cases, respectively. The median OS was 6.2 years. Poorer OS was associated with R-IPI > 3 at transformation (median OS 1.9 y, HR 2.9 [CI 1.5 – 5.9], p<0.0001) (Figure 1), FLIPI1 score 3 or more (median OS 1.7y, HR 2.9 [CI 1.7 – 5.1], p<0.0001), TTT< 2 years (median OS 2.8y, HR 3.2 [0.9 – 10.5], p=0.041), B symptoms (median OS 2.8y, HR 3.1 [1.5 – 6.4] p=0.003) and elevated LDH (median OS 2.8y, HR 2.6[1 – 6.6], p=0.04). The median OS with IPI< 2 was not reached. No survival differences were seen with FL vs non FL histology, older age, extranodal disease, bulky disease, use of RIT, number of treatment lines or rituximab prior to TL. There was a trend towards poorer OS with SA< 3.7 g/dl (median OS 2.8y, p=0.068). Conclusions An R-IPI >3 at transformation was associated with poorer OS in patients with LG-HNL who undergo histological transformation into DLBCL and treated with chemoimmunotherapy. This suggests that R-IPI can be used at the time of transformation to better assess the aggressiveness of disease. A confirmation of these findings will be needed in multicenter and prospective cohorts. Disclosures: No relevant conflicts of interest to declare.
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Fukushima, Toshio. "Report on Astronomical Constants". International Astronomical Union Colloquium 180 (marzo 2000): 417–27. http://dx.doi.org/10.1017/s0252921100000567.
Testo completoAbstract (sommario):
AbstractRecent progress in the determinations of astronomical constants is reviewed. First is the latest estimation of the general relativistic scale constants, LC, LG, and LB (Irwin and Fukushima, 1999). By reestimating the uncertainty, the value of the first constant is given as LC = 1.480 826 867 4 × 10–8 ± 1.4 × 10–17. Also noted is the rigorous relation among these three, LB = LC + LG – LCLG. Based on the latest determination of the geoidal potential W0 in the IAG 1999 Best Estimate of Geodetic Parmeters (Groten, 1999), LG and LB were reevaluated as LG = 6.969 290 09 × 10–10 ± 6 × 10–18 and LB = 1.550 519 767 3 × 10–8 ± 2.0 × 10–17. Since LG is roughly related to W0, a proposal to fix its numerical value is presented in order to remove the geophysical ambiguity in its evaluation in the future. In that case, LG becomes a defining constant for the scale difference between the geocentric and terrestrial coordinate systems. While LC and LB remain as a primary and derived constant, respectively. Next is the correction to the current precession constant, Δp. The recent estimates of Δp based on Very Long Baseline Interferometry (VLBI) observation seem to converge to a value close to –0.30″/cy (Mathews et al., 2000; Petrov, 2000; Shirai and Fukushima, 2000; Vondrák and Ron, 2000). Unfortunately this is significantly different from –0.34″/cy, the latest value determined from the Lunar Laser Ranging (LLR) data (Chapront et al., 1999). The difference is roughly ten times larger than the sum of their formal uncertainties. Since the cause of this difference is not clear, we first arranged the best estimates based on VLBI and LLR techniques, respectively, then took a simple mean of these two best estimates, and recommend it as the current best estimate. The value derived is p = 5 028.78 ± 0.03 ″/cy. Similar estimates were given for some other quantities related to the precession formula; namely the correction to the obliquity rate of the IAU 1976 precession formula (Lieske et al., 1977), Δε1 = (–0.024 5 ± 0.002 5) ″/cy, and the offsets of the Celestial Ephemeris Pole of the International Celestial Reference System, Δψ0 sin ε0 = (–17.5 ± 0.8) mas and Δε0 = (–5.2 ± 0.4) mas. As a result, the obliquity of the ecliptic at the epoch J2000.0 was estimated as ε0 = 23°26′21.″405 6 ± 0.″000 5. The draft IAU 2000 File of Current Best Estimates of astronomical constants, that is to replace the 1994 version (Standish, 1995) or maybe even the formal IAU 1976 System of Astronomical Constants (Duncombe et al., 1977), after discussion at the 24th General Assembly of the IAU is presented.
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Muhammad Akrim, Zikri Habibie, e Filson Maratur Sidjabat. "Study of Manufacture Company Strategy in Implementing ISO 9001:2015 & ISO 140001". UNM Environmental Journals 2, n. 2 (26 aprile 2019): 28. http://dx.doi.org/10.26858/uej.v2i2.10081.
Testo completoAbstract (sommario):
In early 1980’s environmental issues were increasing, several policies were made in countries as a concern to environment, even the government has the policy about environment. One of the standards used in company related to environment is ISO 14001.Beside environmental management system companies need to get an international confession stating that their products and systems are appropriate. The international standard related to the quality management that can be used is ISO 9001:2015.In this study author try to comparing manufacturing company such asPT. Apac Inti Corpora, Omron Manufacturing and LG Electronicstrategy in implementing the ISO 9001:2015 and ISO 14001:2015 certification.
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Eden, Aimee R. "An Oral History Interview With Leon Gross, PhD". Journal of Human Lactation 35, n. 3 (3 maggio 2019): 408–12. http://dx.doi.org/10.1177/0890334419844987.
Testo completoAbstract (sommario):
One of the distinguishing and unique features of being an International Board Certified Lactation Consultant is successful completion of the International Board of Lactation Consultant Examiners examination, necessary for initial and ongoing certification. First offered in 1985, the exam content and scoring criteria have been developed using rigorous psychometric principles. While conducting my dissertation research about the professionalization of breastfeeding support (Eden, 2017), I interviewed Leon Gross, PhD, the psychometrician who oversaw the development of the first exam offered in 1985. He continued in this role through 2013. The interview excerpts below are from a taped interview conducted on March 27, 2011 in Rosslyn, Virginia (AE = Aimee Eden; LG = Leon Gross).
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McManus, Michael. "Section 337 by the Numbers: Trends in IP Enforcement at the US International Trade Commission". Global Trade and Customs Journal 6, Issue 5 (1 maggio 2011): 219–21. http://dx.doi.org/10.54648/gtcj2011030.
Testo completoAbstract (sommario):
Many intellectual property mega cases concerning allegedly infringing goods imported into the United States end up in front of the United States International Trade Commission. Past investigations include billion dollar tech cases between global powerhouses like Nokia, Qualcomm, RIM, Samsung, LG, Sharp, HP, and many others. Despite the economic significance of these cases, there is a relative dearth of statistical analysis of recent trends. This article seeks to supply such information by an analysis of every section 337 complaint filed in the calendar year 2009 (the most recent year for which most investigations have been resolved).
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Zarra, Giovanni. "Orderliness and Coherence in International Investment Law and Arbitration: An Analysis Through the Lens of State of Necessity". Journal of International Arbitration 34, Issue 4 (1 agosto 2017): 653–78. http://dx.doi.org/10.54648/joia2017031.
Testo completoAbstract (sommario):
The article addresses the need for orderliness and coherence in international investment law. It does so by reference to Argentina’s various claims to necessity in CMS, LG&E, Continental Casualty Co., Enron and Sempra. After having analysed the various doctrinal positions regarding orderliness of international investment law and the need for coherence in this area of international law (both from the perspective of the consistency among investment awards and from the perspective of the integration of other areas of international law within investment disputes), the work reaches the conclusion that arbitrators should endorse an approach according to which, on the one hand, they should not ignore what is done by other tribunals (we can talk of investment arbitration as a network needing internal coherence) and, on the other hand, they should always take into consideration values protected by other areas of international law and general international law (in which investment arbitration is fully integrated).
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Taylor, Steven R., e Hans E. Hartse. "An evaluation of generalized likelihood ratio outlier detection to identification of seismic events in western China". Bulletin of the Seismological Society of America 87, n. 4 (1 agosto 1997): 824–31. http://dx.doi.org/10.1785/bssa0870040824.
Testo completoAbstract (sommario):
Abstract The generalized likelihood ratio outlier detection technique for seismic event identification is evaluated using synthetic test data and frequency-dependent Pg/Lg measurements from western China. For most seismic stations that are to be part of the proposed International Monitoring System (IMS) for the Comprehensive Test Ban Treaty (CTBT), there will be few or no nuclear explosions in the magnitude range of interest (e.g., mb < 4) on which to base an event-identification system using traditional classification techniques. Outlier detection is a reasonable alternative approach to the seismic discrimination problem when no calibration explosions are available. Distance-corrected Pg/Lg data in seven different frequency bands ranging from 0.5 to 8 Hz from the Chinese Digital Seismic Station WMQ are used to evaluate the technique. The data are collected from 157 known earthquakes, 215 unknown events (presumed earthquakes and possibly some industrial explosions), and 18 known nuclear explosions (1 from the Chinese Lop Nor test site and 17 from the East Kazakh test site). A feature selection technique is used to find the best combination of discriminants to use for outlier detection. Good discrimination performance is found by combining a low-frequency (0.5 to 1 Hz) Pg/Lg ratio with high-frequency ratios (e.g., 2 to 4 and 4 to 8 Hz). Although the low-frequency ratio does not discriminate between earthquakes and nuclear explosions well by itself, it can be effectively combined with the high-frequency discriminants. Based on the tests with real and synthetic data, the outlier detection technique appears to be an effective approach to seismic monitoring in uncalibrated regions.
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Willatt, Lionel, e Sian M. Morgan. "Shaffer LG, Slovak ML, Campbell LJ (2009): ISCN 2009 an international system for human cytogenetic nomenclature". Human Genetics 126, n. 4 (4 agosto 2009): 603–4. http://dx.doi.org/10.1007/s00439-009-0726-6.
Testo completo
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Mahabir, Amrita, Lambert A. Motilal, David Gopaulchan, Saila Ramkissoon, Antoinette Sankar e Pathmanathan Umaharan. "Development of a core SNP panel for cacao (Theobroma cacao L.) identity analysis". Genome 63, n. 2 (febbraio 2020): 103–14. http://dx.doi.org/10.1139/gen-2019-0071.
Testo completoAbstract (sommario):
Single nucleotide polymorphisms (SNPs) are preferred markers for DNA fingerprinting and diversity studies in cacao (Theobroma cacao L.). Yet, a consensus SNP panel with a minimum number of SNPs for optimal identity analysis is unavailable for cacao. An initial set of 146 SNP panels of varying sizes were assembled based on heterozygosity, linkage disequilibrium (LD), linkage group (LG) distribution, major allele frequency, minor allele frequency (MiAF), polymorphism information content (PIC), and random distribution. These panels were assessed to determine their ability to distinguish among a training set of 155 accessions. The panels with the best separation ability were supplemented with additional SNPs to create 16 designer panels, which separated all 155 accessions. The 16 designer SNP panels were then assessed on a dataset of 1220 accessions coming from 10 ancestral groups. Increasing the number of SNPs generally yielded improved resolution of genetic identities with concomitant reduction of synonymous groups. The number and choice of SNPs were critical factors with LD, MiAF, and PIC being important selection attributes but an even LG distribution was unnecessary. A robust set of 96 SNPs is recommended as a minimal core SNP panel for cacao DNA fingerprinting to the international cacao community.
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Griffin, Patrick T., Samir Dalia, Bijal D. Shah, Lubomir Sokol, Celeste M. Bello, Paul A. Chervenick, Eduardo M. Sotomayor e Julio C. Chavez. "Multivariate Survival Analysis of Transformed Lymphoma in the Chemoimmunotherapy Era: Impact of the NCCN International Prognostic Index". Blood 124, n. 21 (6 dicembre 2014): 2981. http://dx.doi.org/10.1182/blood.v124.21.2981.2981.
Testo completoAbstract (sommario):
Introduction: Histologic transformation (HT) in patients with low-grade Non-Hodgkin lymphoma (LG-NHL) has historically been associated with poor survival. We previously described the predictive value of the revised international prognostic index (R-IPI) to differentiate patients into good and poor-risk survival groups. The recently developed NCCN international prognostic index (NCCN-IPI) has demonstrated improved discrimination capacity over the IPI in patients with de novo DLBCL. Here, we investigate the utility of the NCCN-IPI in patients with transformed lymphoma (TL) and further assess the impact of relevant clinical variables on survival in a multivariate analysis. Methods Patients with a biopsy proven diagnosis of DLBCL transformed from LG-NHL were identified between January 2001 and December 2011 through the Moffitt Cancer Center Total Cancer Care Database. Patients with Richter's transformation were excluded. All patients received rituximab-based chemotherapy at HT. Risk scores were calculated for all patients based on variables at the time of TL diagnosis. Progression free survival (PFS) and overall survival (OS) were calculated from the date of transformation, estimated by the Kaplan-Meier method (K-M), and compared using the long-rank test. Predictors of survival were assessed using the Cox proportional hazards model, and multivariate analyses of significant factors were assessed by backward elimination. Results A total of 79 patients with transformed DLBCL were identified. The median age at transformation was 64 years (range 21 – 88). The most common original LG-NHL diagnosis was follicular lymphoma (74.7%) followed by marginal zone lymphoma (21.5%). The majority of patients (89.9%) presented with stage III/IV disease at transformation. The most common treatment regimen at transformation was R-CHOP (81%) followed by R-ICE (12.7%).] The median PFS for the entire group was 1.98 years (95% CI, 1.28-2.67) and the median OS was 4.49 years (95% CI, 2.52-6.47). The NCCN-IPI risk model demonstrated better discrimination of survival risk and was able to identify 3 statistically distinct groups by log-rank analysis, p<0.001 (Figure 1). The R-IPI scoring systems was only able to identify 2 risk groups within this TL population, p=0.010 (Figure 2). A comparison of the estimated 2-year PFS and OS between the R-IPI and NCCN-IPI scoring systems is demonstrated in Table 1. Of note, the NCCN-IPI identifies a particularly poor risk survival group within the "high-risk" category with an estimated 2-year OS of 0% versus 57% for the "poor-risk" R-IPI group. On univariate analysis of OS, performance status (HR 1.56, p=0.037), elevated LDH (HR 3.02, p=0.001), the presence of B-symptoms (HR 2.14, p=0.026), the original FLIPI score at the time of original LG-NHL diagnosis (HR 2.86, p<0.001), the R-IPI (HR 2.29, p=0.012), and the NCCN-IPI (HR 4.57, p<0.001) were all significantly correlated with survival. Further risk stratification by serum albumin <3.7, which we have previously described in the context of de novo DLBCL, was not statistically significant in this TL cohort (HR 1.66, p=0.215). Additionally, there was no significant correlation with older age (0.065), advanced stage (p=0.793), prior treatment (p=0.249), cell of origin (p=0.379), time to transformation (p=0.496), or autologous transplant (p=0.418). On multivariate analysis of overall survival, both the original FLIPI score (HR 2.04, p=0.032) and the NCCN-IPI (HR 4.17, p=0.002) retained statistical significance. Conclusions The NCCN-IPI scoring system demonstrated superior discrimination of survival risk over the R-IPI among patients with transformed Non-Hodgkin Lymphoma and was the strongest predictor of progression free and overall survival at the time of transformation on multivariate analysis. The categorization of a high-risk group with an extremely poor 2-year overall survival, identifies a subset of patients who might benefit from more aggressive or experimental approaches. Figure 1 Figure 1. Table 1. Risk Category (n=79) Risk Score 2 yr OS 2 yr PFS R-IPI (%) NCCN-IPI (%) R-IPI NCCN-IPI R-IPI NCCN-IPI Low / Very Good 0 (0) 0-1 (0) Low-Intermediate / Good 1-2 (59.5) 2-3 (51.9) 80% 88% 59% 63% High-Intermediate 4-5 (40.5) 63% 40% High / Poor 3-5 (40.5) 6 (7.6) 57% 0% 35% 0% Figure 2 Figure 2. Disclosures No relevant conflicts of interest to declare.
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Ghaedi Heidari, Mehran, Hamed Alibeigi e Ali Aghaeifar. "An analytical study on customer perception of store environment and its effect on brand loyalty through joy of shopping (a case study: LG home appliance store)". Problems and Perspectives in Management 14, n. 3 (15 settembre 2016): 380–87. http://dx.doi.org/10.21511/ppm.14(3-si).2016.11.
Testo completoAbstract (sommario):
This study attempted to analyze customer perception of environment in an LG store and its effect on brand loyalty through joy of shopping. This was an applied, descriptive-correlational research involving a survey. The population included all buyers of LG home appliances at stores based in Isfahan. Moreover, simple random sampling was employed. Validity of the questionnaire was calculated through content validity and confirmatory factor analysis, while its reliability was confirmed through Cronbach’s alpha at 0.88. Of the 250 questionnaires distributed among customers, 231 were completed and returned for analysis. Data were analyzed through SPSS and AMOS based on descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (confirmatory factor analysis, path analysis with significance level). According to the results, the main hypothesis was proved, suggesting there is a significant relationship between store environments through joy of shopping on customer loyalty. Furthermore, the subhypotheses were proved, suggesting environment, human interaction and in-store design affect joy of shopping and joy shopping, in turn, affects customer loyalty. In comparison of the research hypotheses, environment left the greatest impact on joy of shopping, followed by human interaction and store interior design are effective in joy of shopping. Finally, there are three components of environment, human interaction and design indirectly leaving a significant effect on brand loyalty through joy of shopping as a mediating variable. Keywords: joy of shopping, store environment, consumer behavior, brand loyalty. JEL Classification: D11, D12, M31
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Marote, Isa Azevedo de Almeida, e Dagmar de Paula Queluz. "Absenteeism study in a steel industry of São José dos Campos, SP, Brazil". Brazilian Journal of Oral Sciences 15, n. 2 (20 aprile 2017): 124. http://dx.doi.org/10.20396/bjos.v15i2.8648754.
Testo completoAbstract (sommario):
Aim: To identify the factors involved in absenteeism in a steel industry in the city of São Jose dos Campos, São Paulo, Brazil. Methods: A cross-sectional study was carried out after obtaining permission from Institutional Ethics Committee in a steel industry. Worker's detailed information regarding absenteeism was obtained from the Health Department files, from January 2005 to December 2008. Specifical data were: sex, function, certificate type (medical or dental), the working sector, according to the Large Groups (LG) of Brazilian Classification of Occupations - 2002, working periods, duration of absenteeism (lost days), the main causes of absenteeism (International Classification of Diseases ICD-10). Results: A total of 570 workers were recorded. The majority of workers were males (97%), with medical certificate (97%), LG-7 workers in the production of industrial goods and services (62.09%), and operators of industrial machinery (68.3%) and the working period was Shift 4 - Monday to Friday from 8 am to 12 am and 1 pm to 5 pm (44.43 %). The total duration of absenteeism was 3,187 days, the main causes of diseases being problemas in the musculoskeletal system and connective tissue (18.48%), respiratory diseases (17.11%), injuries, poisoning and other external causes (11.24%), and diseases of the digestive tract (11.24%). Conclusions: It was concluded that there was under-reporting of absenteeism due to dental causes (41 events) during the study period. More studies in this field are required.
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Koh, Benson, Nadiah Sulaiman, Mh Busra Fauzi, Jia Xian Law, Min Hwei Ng, Too Lih Yuan, Abdul Ghani Nur Azurah, Mohd Heikal Mohd Yunus, Ruszymah Bt Hj Idrus e Muhammad Dain Yazid. "A Three-Dimensional Xeno-Free Culture Condition for Wharton’s Jelly-Mesenchymal Stem Cells: The Pros and Cons". International Journal of Molecular Sciences 24, n. 4 (13 febbraio 2023): 3745. http://dx.doi.org/10.3390/ijms24043745.
Testo completoAbstract (sommario):
Xeno-free three-dimensional cultures are gaining attention for mesenchymal stem cell (MSCs) expansion in clinical applications. We investigated the potential of xeno-free serum alternatives, human serum and human platelet lysate, to replace the current conventional use of foetal bovine serum for subsequent MSCs microcarrier cultures. In this study, Wharton’s Jelly MSCs were cultured in nine different media combinations to identify the best xeno-free culture media for MSCs culture. Cell proliferation and viability were identified, and the cultured MSCs were characterised in accordance with the minimal criteria for defining multipotent mesenchymal stromal cells by the International Society for Cellular Therapy (ISCT). The selected culture media was then used in the microcarrier culture of MSCs to determine the potential of a three-dimensional culture system in the expansion of MSCs for future clinical applications, and to identify the immunomodulatory potential of cultured MSCs. Low Glucose DMEM (LG) + Human Platelet (HPL) lysate media appeared to be good candidates for replacing conventional MSCs culture media in our monolayer culture system. MSCs cultured in LG-HPL achieved high cell yield, with characteristics that remained as described by ISCT, although the overall mitochondrial activity of the cells was lower than the control and the subsequent effects remained unknown. MSC microcarrier culture, on the other hand, showed comparable cell characteristics with monolayer culture, yet had stagnated cell proliferation, which is potentially due to the inactivation of FAK. Nonetheless, both the MSCs monolayer culture and the microcarrier culture showed high suppressive activity on TNF-α, and only the MSC microcarrier culture has a better suppression of IL-1 secretion. In conclusion, LG-HPL was identified as a good xeno-free media for WJMSCs culture, and although further mechanistic research is needed, the results show that the xeno-free three-dimensional culture maintained MSC characteristics and improved immunomodulatory activities, suggesting the potential of translating the monolayer culture into this culture system in MSC expansion for future clinical application.
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KIM, Jayeong. "Analytical Science Research Institute of LG Chem - Battery Material Research with Raman Spectroscopy". Physics and High Technology 32, n. 5 (31 maggio 2023): 8–11. http://dx.doi.org/10.3938/phit.32.013.
Testo completoAbstract (sommario):
Raman spectroscopy is used in a wide range of research fields due to its non-destructive and sensitive detection properties. Because of this versatility, Raman spectroscopy is used not only in the physical field but also in battery research in the chemical field. This article briefly introduces about the Analytical Science Research Institute of LG Chem and two cases for cathode material analysis using Raman spectroscopy. Hopefully this explains how physics is used in chemical companies.
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Ahn, Hyejeong. "Assessing proficiency in the National English Ability Test (NEAT) in South Korea". English Today 31, n. 1 (17 febbraio 2015): 34–42. http://dx.doi.org/10.1017/s0266078414000522.
Testo completoAbstract (sommario):
The English language as a symbolic resource holds more notable cultural and social significance in South Korea than any other foreign language. In the current trend of globalisation, proficient English skills have been identified by the government as a critical resource for the country's survival, and developing these skills has been a major priority in all areas. A number of elite universities and sought-after conglomerates such as Samsung, LG and Hyundai have policies which noticeably favour and recruit students with high English proficiency levels (Lee, 2006: 67). In particular, scores achieved in the international proficiency tests such as the TOEIC (Test of English for International Communication) and TOEFL (Test of English as a Foreign Language), in preference to scores gained in other English tests, have become a major determining factor in gaining employment and promotion. According to the Samsung Economic Research Institute between 2004 and 2005, 102,340 Koreans sat for TOEFL. Koreans represented 18.5% of the total 554,942 people taking the test worldwide and they spend 700 billion Won (approximately US$700 million) a year on tests to evaluate their English proficiency.
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Rodgers, Arthur J., William R. Walter, Craig A. Schultz, Stephen C. Myers e Thorne Lay. "A comparison of methodologies for representing path effects on regional P/S discriminants". Bulletin of the Seismological Society of America 89, n. 2 (1 aprile 1999): 394–408. http://dx.doi.org/10.1785/bssa0890020394.
Testo completoAbstract (sommario):
Abstract Short-period regional P/S amplitude ratios hold much promise for discriminating low-magnitude explosions from earthquakes in a Comprehensive Test Ban Treaty (CTBT) monitoring context. However, propagation path effects lead to variability in regional-phase amplitudes that, if not accounted for, can reduce or eliminate the ability of P/S ratios to identify the seismic source. Here we compare four different methodologies that account for the effect of heterogeneous structure on P/S amplitude variance: (1) distance corrections, (2) path-specific crustal waveguide parameter regressions, (3) cap averaging (running mean smoothing), and (4) kriging. The predictability of each method is established by cross-validation (leave-one-out) analysis. We apply these techniques to Pn/Lg, Pg/Lg, and Pn/Sn observations in three frequency bands from 0.75 to 6.0 Hz at station ABKT (Alibek, Turkmenistan), site of a primary station of the International Monitoring System (IMS). Paths to ABKT sample diverse crustal structures (e.g., various topographic, sedimentary, and geologic structures), leading to great variability in the observed P/S amplitude ratios. For these data to be useful for isolating source characteristics, the scatter needs to be reduced by accounting for the path effects, and the resulting distribution needs to be Gaussian for most existing spatial interpolation and discrimination strategies to have valid application. Each method reduces the scatter of the P/S amplitude measurements with varying degrees of success; however, kriging has the distinct advantages of providing the greatest variance reduction and a continuous correction surface with an estimate of the model uncertainty. The largest reductions in scatter are found for the lowest frequency P/S ratios (<3.0 Hz).
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Knol Radoja, Katarina. "IZUZEĆE OD JURISDIKCIJE U EUROPSKOM GRAĐANSKOM PROCESNOM PRAVU". Pravni vjesnik 38, n. 2 (luglio 2022): 21–36. http://dx.doi.org/10.25234/pv/21767.
Testo completoAbstract (sommario):
The paper analyses the right to be exempt from jurisdiction (immunity) under customary international law and European civil procedural law following the interpretation of the Court of Justice of the European Union. The aim is to research the balance between this right and the right of access to the courts as its potentially restrictive factor in the case law of the Court of Justice of the European Union and to compare it with the case law of the European Court of Human Rights. In deciding the LG and Others v. Rina and Ente Registro Navale as the most important case in this regard, the Court of Justice of the European Union states that the national court before which the issue of exemption from jurisdiction arises, must be persuaded that there will be no violation of the right of access to the courts, if it accepts the immunity objection. In this way, the Court determined the limit of exemption from jurisdiction by allowing the waiver of jurisdiction for reasons of compliance with international legal obligations and noting the need to preserve fundamental rights. However, as to the terms of that limitation, the Court remained vague.
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Ko, Kyong Jin, Sanghyun Park e Seongyeon Shin. "An Examination On Factors That Influence The Creation Of Economic Value Added To The Professional Teams: Focusing On Korea Baseball Organization (KBO)". Journal of Applied Business Research (JABR) 37, n. 2 (1 marzo 2021): 61–72. http://dx.doi.org/10.19030/jabr.v37i2.10373.
Testo completoAbstract (sommario):
The research seeks to derive the economic value added (EVA) of 6 franchises from the Korea Baseball Organization (KBO) and concurrently investigate the revenue components contributing to EVA. EVA is regarded as one of the efficient methods on estimating or assessing corporations’ actual economic benefits. For the procedure, financial statements of domestic professional baseball teams for 3 consecutive years (2016-2018), which were released to the Data Analysis Retrieval and Transfer System (DART) of the Financial Supervisory Service (FSS), were utilized. First, NOPLAT, IC, ROIC, and WACC, which refer to essential elements of estimating the EVA, were calculated respectively. Second, Pearson's correlation analysis was conducted between the EVA and the profit indicated in the income statement of the 6 teams. The results of the study are as follows: In case of Doosan, LG and SK, main business revenues showed the highest correlation with EVA, and Kiwoom and Samsung showed the highest correlation with EVA through the contributing factor of ticket sales revenue. Finally, for Lotte, advertising revenue was highly correlated with bringing EVA to the team
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Rooke, J. A., H. Fraser, M. Shanks e A. Morgan. "The potential for improving soya-bean meal in diets for weaned piglets by protease treatment: comparison with other protein sources". Proceedings of the British Society of Animal Science 1996 (marzo 1996): 136. http://dx.doi.org/10.1017/s1752756200593326.
Testo completoAbstract (sommario):
Vegetable proteins, including soya-bean meal (SBM), can only be included in diets for newly-weaned piglets in restricted amounts as they can induce a transient local gut hypersensitivity. This hypersensitivity may be a causative factor in post-weaning diarrhoea. The object of the current experiment was to assess whether protease treatment of SBM could reduce in vitro antigenicity of SBM and improve its nutritional value when fed to newly weaned piglets.Soya-bean meal was treated for 3 h at 50°C at 800 g water / kg. Treatment was carried out at pH 4.5 without and with lg protease P2 (Finnfeeds International Ltd) / kg soya-bean meal dry matter (DM). Treated SBM was neutralised and dried at 65°C before inclusion into diets. The diets were formulated to contain 14.5 MJ Digestible Energy (DE), 190 g crude protein (CP) and 12 g total lysine / kg.
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Rooke, J. A., H. Fraser, M. Shanks e A. Morgan. "The potential for improving soya-bean meal in diets for weaned piglets by protease treatment: comparison with other protein sources". Proceedings of the British Society of Animal Science 1996 (marzo 1996): 136. http://dx.doi.org/10.1017/s0308229600031032.
Testo completoAbstract (sommario):
Vegetable proteins, including soya-bean meal (SBM), can only be included in diets for newly-weaned piglets in restricted amounts as they can induce a transient local gut hypersensitivity. This hypersensitivity may be a causative factor in post-weaning diarrhoea. The object of the current experiment was to assess whether protease treatment of SBM could reduce in vitro antigenicity of SBM and improve its nutritional value when fed to newly weaned piglets.Soya-bean meal was treated for 3 h at 50°C at 800 g water / kg. Treatment was carried out at pH 4.5 without and with lg protease P2 (Finnfeeds International Ltd) / kg soya-bean meal dry matter (DM). Treated SBM was neutralised and dried at 65°C before inclusion into diets. The diets were formulated to contain 14.5 MJ Digestible Energy (DE), 190 g crude protein (CP) and 12 g total lysine / kg.
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Ferrario, Andrea, Alessio Aghemo, Maria Cecilia Goldaniga, Michele Merli, Daniele Vincenti, Francesca Gaia Rossi, Elisabetta De Gasperi et al. "Indolent B-Cell Lymphomas Treated Upfront with Antiviral Therapy: a Series of 13 Patients". Blood 116, n. 21 (19 novembre 2010): 2876. http://dx.doi.org/10.1182/blood.v116.21.2876.2876.
Testo completoAbstract (sommario):
Abstract Abstract 2876 Background: HCV infection has been demonstrated to be involved in clonal B cell proliferation and in the subsequent development of non-Hodgkin's lymphoma (NHL). The regression of NHL after antiviral treatment is considered an indirect evidence of this pathogenetic relationship. Aim: to evaluate clinical course of patients affected by HCV infection (serology and HCV RNA positive) and low grade B-cell NHL (LG-NHL), not needing immediate treatment (absence of B symptoms, bulky disease or symptomatic tumor mass and lymphocyte doubling time less than 6 months) and treated upfront with antiviral therapy alone. Method: From 2006 to 2010, 13 patients, affected by LG- NHL at diagnosis have been treated with pegylated interferon (PegIFNa2a, 100–180 mcg weekly) and ribavirin (Rbv, 800–1200 mg daily) for a median treatment period of 6 months (6-18 months). Two patients are still in treatment. M/F ratio was 1.6 and median age was 59 years (range 51–73). The study included 9 marginal zone lymphomas (MZL: 2 splenic MZL, 7 extranodal non gastric MZL), 3 LG-NHL NOS and 1 lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia (LPL). Cryoglobulin were present in five patients. 7 pts had genotype 2, 5 pts genotype 1b, one not assessed; HCV infection was detected before lymphoma diagnosis in 9 pts and at lymphoma onset in 4 pts. Only 2 patients have previously received other combinations of antiviral therapy. Virologic response was assessed monthly by HCV-RNA polymerase chain reaction (PCR) and hematologic response was evaluated according to International Working Group response criteria (Cheson et al. J Clin Oncol. 2007) at the end of antiviral therapy. Results: Eleven patients completed the planned treatment course. Sustained virologic response (SVR) was achieved in 9 patients (6 with genotype 2); viremia clearance was achieved in a median period of 2 months (1-6). Among patients that gained a SVR, 5 achieved a complete response (CR) (3 genotype 2, 1 1b, one not assessed), one (genotype 2) partial response (PR), and 3 (2 genotype 2 and one genotype 1b) presented stable disease (SD). The remaining patients obtained only a reduction of viremia: one presented a SD and one was in PR. The treatment was well tolerated without any WHO grade III-IV toxicity. Among patients that completed treatment program, more frequent toxicity was haematological (one patient developed a WHO grade 1 anemia and one patients developed WHO grade 1 anemia and grade 2 neutropenia). After a median follow up of 17 months from the end of therapy (range 3–44), considering the 9 patients in SVR, only 2 (1 CR and 1 PR) progressed, maintaining SVR and one lost SVR maintaining SD. Patients that obtained only a reduction of viremia, maintained their hematologic status. Conclusion: We described a high CR rate in patients that obtained SVR after antiviral therapy (55%); the relationship between hematologic and viral response during follow up is not always stringent. We confirm that antiviral therapy could be considered as frontline therapeutic option in cases of HCV-related LG-NHL not requiring immediately immunochemotherapy. Disclosures: No relevant conflicts of interest to declare.
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Lapovok, I. A., A. E. Lopatukhin, A. A. Kirichenko, A. V. Murzakova e D. E. Kireev. "COMPARATIVE ANALYSIS OF DIAGNOSTIC KITS FOR THE QUANTITATIVE DETERMINATION OF HIV-1 RNA PRODUCED IN RUSSIA". HIV Infection and Immunosuppressive Disorders 12, n. 1 (26 maggio 2020): 123–33. http://dx.doi.org/10.22328/2077-9828-2020-12-1-123-133.
Testo completoAbstract (sommario):
Aim: to carry out the comparative analysis of Russian kits for HIV-1 viral load (VL) measuring: AmpliSens HIV-monitor-FRT, AmpliSens HIV-monitor-Duo-FL, RealBest RNA HIV quantitative, HIV-GEN quantitative.Materials and methods: we analyzed the collection of clinical blood plasma samples with VL 590–2,05×106 copies/ml, dilutions of HIV-1 2nd International Standard, as well as panels of subtypes and recombinant forms of HIV-1 group M. The convergence of the results was determined using the Spearman correlation analysis and the Bland-Altman method.Results. A high level of convergence of VL measuring results in clinical samples (n=76) was determined for all compared kits with the value of approximation reliability R of at least 0,85. The maximum difference between the median values of VL results (0,48 log, ≈3-fold) was obtained for HIVMonitor-FRT and RealBest quantitative, which did not exceed the acceptable discordance rate in two kits comparing. All dilutions of the 2nd international HIV-1 standard were successfully determined by all kits with middle error 0,16–0,34 lg copies/ml. All kits successfully revealed the most of HIV-1 subtypes and recombinants studied with middle deviation 0,02–0,56 log copies/ml. HIV-GEN quantitative demonstrated the highest accuracy, but didn’t reveal ADG-recombinant.
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Dikčius, Vytautas, e Gintarė Stankevičienė. "Perception of Country of Brand Origin and Country of Product Manufacturing Among Lithuanians and Emigrants From Lithuania". Organizations and Markets in Emerging Economies 1, n. 2 (31 dicembre 2010): 108–22. http://dx.doi.org/10.15388/omee.2010.1.2.14299.
Testo completoAbstract (sommario):
Though the issue of product country of origin has been researched by numerous researchers, due to globalization, currently consumers have more problems perceiving the country of origin than ever before. This brings marketing specialists back to the discussion of the topic once again, with emphasis on a distinction between the country of manufacturing origin and the country of brand origin. The impact of country of manufacturing and country of brand image varies from country to country under the influence of numerous impact factors, often summarized within a culture or subcultures. One type of such subcultures could be formed by immigrants, whose perceptions might include aspects of their home country combined with those of the host country. The main purpose of this paper was to evaluate the attitudes of Lithuanians who live in Lithuania (as a country of an emerging economy) and those of emigrants living in selected countries (Ireland, the United Kingdom and Finland) with regard to the importance of country of origin. Three brands were selected for the research – Panasonic, LG and BEKO, and three different cases were presented to the respondents. First, both the brand name (Panasonic) and the manufacturing country (the United Kingdom) were associated with a developed country. In the second case, country of brand origin (LG) was identified as a developed country while country of manufacture represented an emerging economy (Poland). Finally, an emerging economy of the country of brand origin (BEKO) and an emerging economy of the country of manufacturing (Turkey) were dealt with.Findings provide evidence that, in general, more developed countries had a better image as countries – manufacturers of TV sets than less developed countries (emerging economies). Analysis of opinions about country of brand origin revealed that brands from developed countries were evaluated better than those from emerging economies. In addition, analysis showed that respondents who live in an emerging economy have more positive attitude towards the surveyed brands compared with Lithuanian emigrants to developed countries. Finally, strong correlation was found between the evaluation of a brand and evaluation of the country of brand origin, while there was no correlation between evaluation of a brand and evaluation of country of manufacturing.
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Pasha, Auralia Salsabila Tuada, e Arie Kusuma Paksi. "THE IMPACT OF SOUTH KOREA’S NEW SOUTHERN POLICY ON INDONESIA: ECONOMY AND DEFENSE SECTORS". DIALEKTIKA: Jurnal Ekonomi dan Ilmu Sosial 7, n. 2 (4 settembre 2022): 140–50. http://dx.doi.org/10.36636/dialektika.v7i2.747.
Testo completoAbstract (sommario):
South Korea’s economy has been heavily depend on major power countries such as US, China, Japan, and Russia. However, with the changing dynamics in international world such as growing protectionism in US during Trump leadership, China’s expansion of influence in Asia, as well as trade war between US and China causing President Moon Jae In to switch South Korea’s economy horizon. New Southern Policy is a diplomatic initiative established to reduce those dependence. South Korea invites India and ASEAN as its brand new partners. South Korea stated that Indonesia is a major partner in New Southern Policy. This research aims to analyze the impact of New Southern Policy in Indonesia, especially in economy and defense sectors. The impact on economy sectors are both countries agreed to signed IK-CEPA agreement, South Korea which eager to make Indonesia as new production base in ASEAN through Hyundai company factory construction, and LG Consortium investment in the electric vehicle battery cell industry. Moreover, the impact on defense sectors is joint venture project for the production of KFX/IFX fighter jets.
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Gooberman, Leon. "Business failure in an age of globalisation: Interpreting the rise and fall of the LG project in Wales, 1995–2006". Business History 62, n. 2 (26 gennaio 2018): 240–60. http://dx.doi.org/10.1080/00076791.2018.1426748.
Testo completo
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Saadah, Kholifatus. "The Impact of Samsung Scandal in South Korean Corporate Culture: Is Corporate Governance Necessary?" Jurnal Global & Strategis 11, n. 2 (12 gennaio 2018): 126. http://dx.doi.org/10.20473/jgs.11.2.2017.126-134.
Testo completoAbstract (sommario):
As one of the world’s poorest countries in the world 30 years ago, South Korea proved its remarkable economic development. Within three decades, South Korea’s economic development shot up and attracted international attention. The economic strength in South Korea is supported by several global corporations such as Samsung, LG, Hyundai and others. The corporations have South Korea’s “ala” power, chaebol. Chaebol itself is similar to keiretsu in Japan, which global corporations are run by families and are hereditary. As time goes by, South Korea with its corporate culture does provide many advantages for South Korea as a whole, but this condition does not last forever. Not on the decline in revenues to South Korea’s economy, but the scandal of some global corporations in South Korea, especially Samsung raises new questions, should the South Korean Corporate culture be changed in the future? This question will be answered and explained in this paper. The author will explain through the history of the Korean corporate culture that is influenced by Confucianism, Samsung’s history to become a global corporate power for South Korea as well as an analysis of corporate governance on the economic situation in South Korea.
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Musah-Surugu, Issah Justice, Albert Ahenkan e Justice Nyigmah Bawole. "Local Government Financing of Climate Change in Ghana: Politics of Aid and Central Government Dependency Syndrome". Journal of Asian and African Studies 54, n. 5 (7 dicembre 2018): 619–37. http://dx.doi.org/10.1177/0021909618812911.
Testo completoAbstract (sommario):
Uncertainties about the amount of resources needed to combat climate change, dwindling local resources, limited local autonomy and limited expertise constrain local governments (LGs) in their response to the effects of climate change. As a result, financing climate change remains a major nightmare for LG actors across diverse nested territorial containers. It certainly requires the embracing of a multifaceted approach – the use of system thinking where local governments’ resource husbandry is optimised to support external aid and central government transfer. A multifaceted approach brings onboard blended resources, diverse stakeholders, diverse resource mobilisation skills and schemes, and accountability measures. Also, given projected increases in future climate-induced public expenditure, albeit with uncertainties, reliance on a single resource mobilisation approach will be a recipe for inefficiency. This article argues that developmental aid and central government’s transfer remains inadequate to meet the increasing demand for adaptation cost at the local level in Ghana. In the face of the unequivocal impact of climate change risk, we contend that local resource husbandry must be optimised through different innovations to complement other major sources of financing. Our contention resonates with the school of thought that argues local level resources are more resilient to politicisation, are stable, and are predictable compared to international aid and central government transfer. Through qualitative in-depth interviews, empirical data has been drawn from local governments in Ghana to justify our claims.
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Son, Seungwon, e Juyeon Oh. "A Study on the Performances of AI Recruitment System: A Case Study on Domestic and Abroad Companies". Korean Career, Entrepreneurship & Business Association 7, n. 2 (30 marzo 2023): 137–55. http://dx.doi.org/10.48206/kceba.2023.7.2.137.
Testo completoAbstract (sommario):
This study examines how AI technology is being used in the recruitment process through domestic and international case studies of AI recruitment systems such as Google, Softbank, Unilever, Amazon, Loreal, Samsung, Lotte, SK, KB Kookmin Bank, Hyundai and LG, and seeks to verify the introduction performance of AI recruitment systems, and presents matters to be considered when companies select AI recruitment systems. AI Recruitment system improves the time efficiency, work efficiency, objectivity and accuracy of the recruitment process, allows a wider pool of applicants, and provides more fair opportunities for evaluation to candidates. Despite these effect, the following points should be considered when companies want to introduce AI Recruitment system. 1) AI HRM cannot guarantee positive results for all companies, 2) and companies should have personnel managers who are in charge of AI Recruitment system and a system to apply Recruitment, 3) In addition, the purpose of introducing AI Recruitment system should be established. 4) Also, It should be recognized in advance that the application of AI Recruitment system may show unintended consequences such as prejudice, 5) AI Recruitment system cannot replace everything in the realm of human beings, 6) Finally, since it takes a long time to implement AI Recruitment system in order to examine its effectiveness, companies should review the need for AI Recruitment system as well as cost.
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Vetokhov, Sergey V. "Architectural features of the Ancient Egyptian rock-cut tomb of Kaemnefret (LG 63) on the Eastern Field of the Giza Necropolis". Vostok. Afro-aziatskie obshchestva: istoriia i sovremennost, n. 3 (2023): 240. http://dx.doi.org/10.31857/s086919080024167-0.
Testo completoAbstract (sommario):
The article analyses the structural and planning aspects of the ancient Egyptian rock-cut tomb of royal official Kaemnefret (LG 63) in the Eastern Field of the Giza Necropolis, including two hypotheses of plan development, characteristics of the burial shafts, possible reasons for the absence of “false doors”, purpose of the two passages from room 63A to room 63B and identity of the four statues. The distinctive feature of the tomb is the location of the mouth of a burial shaft outside the chapel, which is not typical for rock-cut tombs and may be an imitation of a mastaba, as proved by the design of some burial shafts. The main question addressed in the article concerns the order in which the two groups of shafts located in rooms 63A and 63B were constructed. Thus, two hypotheses on the development of the tomb were suggested. The main hypothesis supports the idea of the primary construction of the shafts in room 63B and only the subsequent emergence of additional burial shafts in room 63A. The alternative hypothesis is based on the idea of a reverse sequence. The absence of a false door in the tomb is most possibly related to its destruction during the reconstruction process; previously, it had probably existed in place of one of the two passages to room 63B. As a result, most of the architectural criteria allow to date the tomb fairly broadly to the V–VIth Dynasties and only a few details allow to narrow the dating to the late Vth – VIth Dynasties.
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Wu, Xiao Xiao, Woo Jin Choi e JaeHong Park. "“I” see Samsung, but “we” see Samsung and LG: The moderating role of consumers’ self-construals and perceived similarity in spillover effect of product-harm crisis". International Journal of Market Research 62, n. 1 (22 agosto 2019): 79–94. http://dx.doi.org/10.1177/1470785319866404.
Testo completoAbstract (sommario):
Negative spillovers due to firms’ product-harm crises have attracted the attention of marketing researchers owing to the devastating and irrecoverable damage they can cause. Despite the extensive research undertaken on this topic, studies concerning spillovers across competing brands from different companies are relatively scant. Drawing upon self-construal theory, we propose that spillover effects across competing brands from different companies may vary depending on consumers’ self-construal and on the perceived similarity between the brands. The results of two studies show that, when the brands’ perceived similarity is high, the spillover effect of a product-harm crisis on a competing brand from a different company is greater for consumers with interdependent self-construal than for those with independent self-construal. Our findings extend the theoretical knowledge of spillover effects and provide meaningful managerial implications for global corporations.
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Che Ku Kassim, Che Ku Hisam, Suraya Ahmad, Noor Emilina Mohd Nasir, Nur Nariza Mod Arifin e Wan Mohd Nazif Wan Mohd Nori. "Environmental disclosures on local governments' websites: a Malaysian context". International Journal of Public Sector Management 33, n. 6/7 (10 agosto 2020): 663–79. http://dx.doi.org/10.1108/ijpsm-03-2020-0077.
Testo completoAbstract (sommario):
PurposeFirst, the paper examines the extent of environmental disclosures (EDs) made by the Malaysian local governments (LGs) on their websites. Second, it examines the patterns of disclosure with the aim of investigating the underlying motive behind the EDs.Design/methodology/approachA descriptive content analysis was employed to measure the EDs. A disclosure instrument, based on the extant studies, is designed to facilitate the measurement process.FindingsThe results suggest that LGs of various levels, have taken the initiative to report EDs on their websites even in the absence of any statutory reporting regulations either by the state or federal government. Differences in the types of EDs are also apparent and consistent with the premise of legitimacy theory.Originality/valueA paucity of prior studies measuring EDs made at the LG level is observed in the literature. Research evidence focussing on the EDs reported on the websites is even more scarce. This lack of research contributes to a limited understanding on the development and challenges of the environmental reporting practices within the developing country's perspective. Moreover, generalising the findings of studies conducted in developed countries may not be possible due to a number of regulatory, political and socio-economic factors.
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Kochuvilayil, A., S. Rajalakshmi, A. Krishnan, S. M. Vijayanand, V. R. Kutty, T. Iype e R. P. Varma. "Palliative care management committees: a model of collaborative governance for primary health care". Public Health Action 13, n. 1 (1 marzo 2023): 12–18. http://dx.doi.org/10.5588/pha.22.0028.
Testo completoAbstract (sommario):
<sec> <title>SETTING:</title> The community-based primary palliative care programme in Kerala, India, has received international acclaim. Programme functioning is supported through Palliative Care Management Committees (PMCs) at the local government (LG) level. </sec> <sec> <title>OBJECTIVE:</title> To study the functioning of the PMCs within the decentralised governance space to identify achievements, gaps and notable innovations. </sec> <sec> <title>DESIGN:</title> This qualitative study included seven key informant interviews (KIIs), 28 in-depth interviews and a review of relevant publicly available policies and documents. Major themes were recognised from the KII transcripts. Codes emerging from the document review and in-depth interview transcripts were mapped into the identified thematic areas. </sec> <sec> <title>RESULTS:</title> Successful PMCs raised resources like money, human resource, equipment, had good skilled care options for symptom relief and facilitated reduced out-of-pocket expenditure by providing home care and free medicines, and improved access to interventions that addressed the social determinants of suffering like poverty. PMCs had varying managerial and technical capacities. In some LGs, the programme was weak and mostly limited to the supply of medicines, basic aids and appliances to patients’ homes. </sec> <sec> <title>CONCLUSION:</title> Despite varied implementation patterns, PMCs in Kerala are examples of state-supported, community-owned care initiatives, that can potentially address medical and social determinants of suffering. </sec>
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Cyran, Krzysztof A. "Research and Innovation Staff Exchange as a Frame for Collaboration of Higher Education with Industry: Lessons Learned from WrightBroS Horizon 2020 EU Project". Athens Journal of Education 10, n. 4 (16 ottobre 2023): 669–84. http://dx.doi.org/10.30958/aje.10-4-6.
Testo completoAbstract (sommario):
The paper focusses on a collaboration between academia and industry. As an introduction, we present typical behavior of university researchers, who often define the area of application without consulting it with industrial partners, and we propose different approach which led to the definition of the scope of the WrightBroS project. The project, entitled “Collaborative Factory of the Flight Simulators Branch of RISE” is financed by the European Union in the frame of Horizon 2020 MSCA Research and Innovation Staff Exchange (RISE) programme. The international Consortium composed of Higher education (Silesian University of Technology from Poland) and industrial (LG Nexera from Austria and Virtual Reality Media from Slovakia) sectors, has designed a project as a collaborative platform whose know-how results from knowledge sharing among partners. Then, from the experience gained in the implementation of the WrightBroS and other similar projects, by using case-study methodology we demonstrate how representatives of education and industry in the new joint environment supplement each other in common research efforts. We also present methods for knowledge sharing, in particular achieved by intersectoral staff exchanging. Then we present the results achieved by collaboration of Higher Education with Industry in the WrightBroS project. Finally, the discussion in the context of tackling broader challenges of intersectoral collaboration leads to the conclusions that this kind of environment is very efficient way to overcome typical difficulties in academia and industry dialog, which is so common in the global world. Keywords: academia and industry collaboration, Horizon 2020 MSCA, research and innovation staff exchange, Horizon Europe MSCA, Augmented Reality (AR), flight simulators
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Mukambayev, A. S., N. N. Mikhailova e V. I. Dubrovin. "On Monitoring of mining explosions conducted on the territory of the former Semipalatinsk Test Site". Russian Journal of Seismology 6, n. 2 (25 giugno 2024): 27–41. http://dx.doi.org/10.35540/2686-7907.2024.2.02.
Testo completoAbstract (sommario):
Several mineral deposits located on the territory of the former Semipalatinsk Test Site (STS) conduct active blasting activity. The largest number of explosions is carried out at the Karazhyra coal mine. These explosions are recorded by stations of the IGR NNC RK network, three of them are part of the International Monitoring System. These are seismic arrays Borovoye (AS057), Makanchi (PS23), Kurchatov-Cross (AS058). The distances to the mines from these stations are 668 km, 452 km, 68 km, respectively. In total, about 2800 explosions were recorded during 19 years of observations. The analysis of the results of routine processing on operational seismic bulletins of the IGR NNC RK Data Center has shown that the field of received epicenters of explosions exceeds the size of the quarry. A detailed processing of explosions waveforms was carried out to find out the reasons of this scatter. Geotool and DTK – GPMCC software included in the NDC-in-a Box package was used to process and analyze the waveforms. It was found that back azimuth values for different regional phases Pn, Pg, Sn, Lg differ from each other and have different dispersion. There are systematic deviations of back azimuths for some phases from the true one. A clear dependence of the epicenter determination accuracy on the energy (power) of the explosion was noted. Subjective factors in the work of analysts that affect the accuracy of estimates are also found. Processing recommendations to improve accuracy were given for analysts of Kazakhstan National Data Centre (KNDC).
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Shishkov, A. V., D. A. Lozovoy, A. V. Borisov e D. V. Mikhalishin. "Testing of Ferarabivac anti-rabies live vaccine for wild carnivores for its immunogenicity and protectivity". Veterinary Science Today, n. 1 (30 marzo 2020): 31–37. http://dx.doi.org/10.29326/2304-196x-2020-1-32-31-37.
Testo completoAbstract (sommario):
Rabies is one of the most important human and animal viral diseases, being one of the most dangerous zoonoses, causing damage to the central nervous system with an inevitable fatal outcome. This disease is of global concern, and it attracts special attention of international organizations (WHO, OIE, FAO, GARC) and of veterinary services in many countries around the world. A variety of anti-rabies vaccines have been used for specific rabies prevention in wild carnivores, however, the safety and effectiveness of some of them is doubtful. New, more advanced products are being developed, one of which is Ferarabivac, a live oral vaccine. The vaccine was tested for its immunogenicity and protectivity in wild carnivores. The optimal immunizing dose was 2.0 cm3, with the infectivity titre of RV-97 strain of at least 6.00 lg KKID50/cm3. Anti-rabies antibody titres detected in the blood sera of foxes and raccoon dogs 14 days post vaccination, were 0.70 ± 0.18 and 0.73 ± 0.19 IU/cm3, respectively, which provided protection against rabies virus infection (≥ 0.50 IU/cm3). Rabies virus neutralizing antibodies in foxes reached their maximum level of 4.30 ± 0.32 IU/cm3 50 days post vaccination. Antibody titres in vaccinated raccoon dogs also reached their maximum level of 4.53 ± 0.27 IU/cm3 50 days post vaccination. The minimum protective threshold levels of serum neutralizing antibodies was determined 12 months after the vaccination, and it was 0.62 ± 0.28 and 0.71 ± 0.17 IU/cm3 in foxes and raccoon dogs, respectively, which proves the necessity to perform booster vaccination one year later. No animals vaccinated against rabies with Ferarabivac live vaccine showed any clinical signs of the disease during the entire observation period following the challenge test carried out 30 days post vaccination.