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1
Dattilo, Delia. "Folk Songs: Spaces and Reasons. Ruga, Love, Marriage, Departures". Tautosakos darbai 59 (2 giugno 2020): 64–84. http://dx.doi.org/10.51554/td.2020.28367.
Testo completoAbstract (sommario):
This essay sheds light on habits, behaviours, and social practices by focusing on Southern Italian youth and their songs; more specifically, it deals with Calabria in the years between 1850 and the 1900s. Such samples – relics to us – allow us to infer how men and women of that generation communicated within the archaic and highly hierarchical society in which they lived. Sometimes through singing the youth of Southern Italy found a way to bypass prohibitions and to say what could not be normally said in everyday life. Since it is clearly impossible to hear the performers’ original voices, this essay relies on examples of poetry and songs as they were perceived, interpreted and published by philologists, folklorists and anthropologists during the second half of the 1800s. Literature draws on folk song collectors such as Achille Canale, Raffaele De Leonardis, and Francesco De Simone Brouwer. The songs and poems considered deal with the topics of love and disdain (sdegno), while a smaller group deals with the themes of lontananza and spartenza. A combined analysis of folk songs and local literature (Vincenzo Padula, Luigi Accattatis, Cesare Lombroso, Caterina Pigorini Beri et al.) allows us to better understand a context that was based on phenomena such as wooing strategies, kidnappings, ostentation of violence and other social events featured in folk songs, poetry and sayings.
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Bönisch-Brednich, Brigitte. "Folk Narrative in Regions of Intensive Cultural Exchange, Interim Conference of the International Society for Folk Narrative Research (ISFNR), Ragusa, Italy, June 12–16, 2018". Fabula 59, n. 3-4 (7 novembre 2018): 313–15. http://dx.doi.org/10.1515/fabula-2018-0107.
Testo completo
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Biscotti, Nello, e Andrea Pieroni. "The hidden Mediterranean diet: wild vegetables traditionally gathered and consumed in the Gargano area, Apulia, SE Italy". Acta Societatis Botanicorum Poloniae 84, n. 3 (2015): 327–38. http://dx.doi.org/10.5586/asbp.2015.031.
Testo completoAbstract (sommario):
<p>Despite the extensive bio-scientific literature concerning the Mediterranean diet, which emerged in the last three decades, systematic ethnography-centered investigations on a crucial portion of this food system, linked to the traditional consumption of non-cultivated vegetables, are still largely lacking in many areas of the Mediterranean Basin.</p><p>In this research, an ethnobotanical field study focusing on wild vegetables traditionally gathered and consumed locally, was conducted in a few centers and villages located in the Gargano area, northern Apulia, SE Italy, by interviewing twenty-five elderly informants. The folk culinary uses of seventy-nine botanical taxa of wild vascular plants, belonging to nineteen families, were recorded, thus showing a remarkable resilience of traditional environmental knowledge (TEK) related to wild food plants. In particular, approximately one-fourth of the recorded wild vegetables are still very commonly gathered and consumed nowadays, while ten taxa have never been reported in previous ethnobotanical studies conducted in Southern Italy. These findings demonstrate the crucial cultural role played by folk cuisines in preserving TEK, despite significant socio-economic changes that have affected the study area during the past four decades.</p>
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Zalewska-Jura, Hanna. "Circe and Rome. The Origin of the Legend". Studia Ceranea 8 (30 dicembre 2018): 77–87. http://dx.doi.org/10.18778/2084-140x.08.04.
Testo completoAbstract (sommario):
Circe is associated first of all with the episode narrated in the 10th book of the Odyssey, in which she turns Odysseus’s crewmen into pigs using her herbal pharmaka. Odysseus survives due to divine help, his inborn cleverness, and the miraculous herb moly. The fairy-tale theme of the spells of Circe, clearly showing its folk provenance, got entrenched in ancient literature: featured most often in poems of playful content, Circe symbolized the power to subjugate male souls and bodies. From the Hellenistic era to the Byzantine times, however, Circe is mentioned in scholarly works – in the context of the history of Roman Italy. The aim of the present article is, first of all, to analyse the Greek-language source texts and show the ways in which ancient authors managed to connect a character from a folk fairy tale – intrinsically different in form and not identifiable with any heroic myth – with the prehistory of Roman Italy, and even place her among the ancestors of Rome. The considerations also allow us to identify some of the mechanisms of the creation and functioning of the legend as a cultural phenomenon of the ancient world.
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Motti, Riccardo. "Wild Plants Used as Herbs and Spices in Italy: An Ethnobotanical Review". Plants 10, n. 3 (16 marzo 2021): 563. http://dx.doi.org/10.3390/plants10030563.
Testo completoAbstract (sommario):
Wild edible plants are an essential component of people’s diets in the Mediterranean basin. In Italy, ethnobotanical surveys have received increasing attention in the past two centuries, with some of these studies focusing on wild edible plants. In this regard, the literature in Italy lacks the coverage of some major issues focusing on plants used as herbs and spices. I searched national journals for articles on the use of wild food plants in Italy, published from 1963 to 2020. Aims of the present review were to document plant lore regarding wild herbs and spices in Italy, identify the wild plants most frequently used as spices, analyze the distribution of wild herbs and spices used at a national scale, and finally, to describe the most common phytochemical compounds present in wild plant species. Based on the 34 studies reviewed, I documented 78 wild taxa as being used in Italy as herbs or spices. The studies I included in this systematic review demonstrate that wild species used as herbs and spices enrich Italian folk cuisine and can represent an important resource for profitable, integrated local small-scale activities.
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Campagnaro, Marnie. "The Long Reach of Creativity: The Lasting Impact of 1970s Italian Children’s Literature". Bookbird: A Journal of International Children's Literature 62, n. 2 (2024): 5–13. http://dx.doi.org/10.1353/bkb.2024.a929805.
Testo completoAbstract (sommario):
Abstract: Between 1968 and 1980, Italy witnessed a dynamic transformation in children’s literature marked by innovative visual, aesthetic, and educational paradigms, involving a profound assimilation of social, cultural, and political dimensions into children’s literature. Children’s books became hubs of interdisciplinary experimentation in which young readers were to be critical cultural participants. These changes took the forms of playful storytelling, intertextuality, nonlinear narratives, and groundbreaking visual, graphic, and material elements. Pioneering technologies further enriched the sensory experience suffusing these books. This article examines the enduring impact of these transformations on Italian children’s literature, focusing particularly on early literacy. It explores four distinct categories of change: the emergence of radical series, innovative adaptations of folk tales, multisensory training grounds, and a trend toward visual narrative cards. These innovations revolutionized prereading education, emphasizing children’s agency and sensory engagement. In studying these shifts, this research underscores the legacy of early experiments in Italian children’s literature, initiatives that continue to shape contemporary children’s literature and education globally, exemplifying the profound impact of a revolutionary period in children’s publishing.
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Toporkov, Andrey L. "“Dream of the Virgin” in Russian Handwritten and Folklore Traditions (17th – the Beginning of the 21st Century)". Studia Litterarum 8, n. 2 (2023): 268–87. http://dx.doi.org/10.22455/2500-4247-2023-8-2-268-287.
Testo completoAbstract (sommario):
“The Dream of the Virgin” is one of the most widespread Christian Apocrypha. It is known among many European peoples, mainly Orthodox and Catholic, namely Belarusians, Bulgarians, Bosnians, Gagauz, Greeks, Irish, Spaniards, Italians, Macedonians, Germans, Poles, Portuguese, Romanians, Russians, Serbs, Slovenes, Ukrainians, French, Croats, etc. The “Dream of the Virgin” is most widely represented in the folk traditions of Eastern, Southern, Central and Western Europe. Some countries have an old scholarly tradition of studying this plot. Such well-known philologists as Alexander Veselovsky in Russia and Bogdan Petriceicu Hasdeu in Romania wrote about it as early as the 19th century. In the 20th century, this text was studied a lot in Italy, Germany, Romania, Russia, etc. The article proposes a preliminary classification of the main genre versions of the “Dream of the Virgin” in Russian manuscript and folklore traditions.
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Żmidziński, Jakub. "„Wędrowiec-dantofil” w rodzinnej Italii. Stanisław Vincenz a włoska tradycja artystyczna". Poznańskie Studia Polonistyczne. Seria Literacka, n. 38 (15 ottobre 2020): 77–101. http://dx.doi.org/10.14746/pspsl.2020.38.4.
Testo completoAbstract (sommario):
The article is the first attempt at a holistic view of Stanisław Vincenz’s relationship with Italian culture. Since his youth, Vincenz would visit the Italian Peninsula travelling to Venice and, already as an emigrant after World War II, made a few visits to Naples and Tuscany. These journeys resulted in numerous comments included in his essays on Dante Alighieri, as separate overview Z perspektywy podróży (From a traveller’s perspective) and List z Neapolu. Dialog z Czesławem Miłoszem (A letter from Naples. A dialogue with Czesław Miłosz). Italian journeys, interest in Dante and Italian culture (architecture, painting, folk rituals) brought numerous Italian motifs in the tetralogy Na wysokiej połoninie (On a high mountain pasture). The key element is included in volume II, Zwada (Conflict), which describes a group of loggers cutting down trees in a primeval Carpathian forest. In this part, a young Italian dies and is buried after a Hutsul funeral ritual which is not understood by the foreigners. The analysis of the abovementioned motifs shows how important Italian culture was to Vincenz, also in a very personal sense, given the Vincenz family’s distant Venetian roots. One may even claim that for the writer, Italy was almost a family land. Personifying the European spirit, Italy was his “broader” homeland.
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Ichim-Radu, Mihaela Nicoleta. "Vasile Alecsandri: Unique Aspects of the Biographical Itinerary vs. Recovery of the Writer's Memory". Intertext, n. 1/2 (57/58) (ottobre 2021): 76–81. http://dx.doi.org/10.54481/intertext.2021.1.08.
Testo completoAbstract (sommario):
Among the writers of his generation, Alecsandri is the most comprehensive one, expressing not only the patriotic aspirations and desires, but also the discoveries from the universe of the private life and trying to make himself noticed in almost all the main literary genres and species. By different circumstances, Alecsandri gets to travel through Moldavia, Wallachia, Bucovina and Transylvania, to the European part of Turkey, to Italy, Austria, Germany, France, Spain, Great Britain, North of Africa, either for personal pleasure, to accompany Elena Negri, who was trying to find a more favourable climate for her fragile health, or for official business. All these travels and each of them separately are part of the development of his creation, leaving marks in his fiction and poetry and “it is printed on the screen of the human experience which defines his public and private personality”. In one of these travels, Alecsandri will discover the folk poetry, discovery which will profoundly mark his destiny as a writer and it will also have immeasurable consequences on the entire development of the Romanian literature from the last century, but also from the years to follow. As a result of the translations into French, German and English of the folk poems or of some of his original poems, Alecsandri becomes one of our first modern writers who became famous also abroad, being accessible to the foreign world.
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Plyukhanova, Maria B. "“Dream of the Virgin” – “Sogno di Maria” in the Context of Italian Literary and Folk Texts about the Passion of Christ". Texts and History: Journal of Philological, Historical and Cultural Texts and History Studies 3 (2021): 34–61. http://dx.doi.org/10.31860/2712-7591-2021-3-34-61.
Testo completoAbstract (sommario):
The “Dream of the Virgin” is an apocryphon about the Passion of Christ, revealed to the Mother of God in a visionary dream. It circulated among many European nations in the form of a spiritual verse, a narrative, a prayer, or an incantation. Starting with the fundamental work of A. N. Veselovsky, this story has been an important subject of comparative research up to the present day. The oldest manuscripts with texts related to it are of Italian origin and date back to the 14th and 15th centuries. The article presents features of the Italian tradition of the apocryphon in texts preserved in these early manuscripts and in more recent folklore recordings. In Italy, the “Dream of the Virgin” existed in the context of various poetic texts about the Passion of Christ and the Lament of the Virgin Mary. The development of Italian volgare literature on the theme of the Passion is associated with the cult of the Passion of Christ, which was extremely widespread in the 13th and 14th centuries. Some details in the Italian texts suggest that the motif of the Virgin Mary’s dream about the Passion possibly originated in the tradition of the Holy Land related to the Mount of Olives and Gethsemane
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Liugaitė-Černiauskienė, Modesta. "Ballads in Oral and Written Tradition: Retrospective Research Survey". Tautosakos darbai 55 (25 giugno 2018): 13–35. http://dx.doi.org/10.51554/td.2018.28497.
Testo completoAbstract (sommario):
The article aims at reviewing the rich and ambivalent Western folk ballad research tradition in terms of confluence of the oral and written traditions. Although being well-reflected in the West, this approach is hardly at all present in Lithuania. The article starts with discussing such cultural phenomenon as broadside ballads. In surveying them, the author maintains that popular publications of the 16th–19th century Europe (bibliothèque bleue, skyllingtricker, Volksbuch, pliegos de cordel, лубочная литература, etc.) were an inherent part of the folk culture. Printed sheets of folksongs and ballads used to be popular in Great Britain, the Netherlands, France, Italy, Spain, Germany, and subsequently in America. However, although spread and promoted by the press, the ballads hardly ascended the field of interest of the educated elite, remaining instead in the “lower” spheres of the popular culture.The first collectors of ballads from the 18th century (the “antiquarian period”) paid little attention to the sources of their material, being instead very keen on improving and elaborating of the ballad texts, and presenting them as creative manifestations of the “original bard” or the “national muse”. After the collections by Thomas Percy and Walter Scott appeared, William Motherwell turned back to the still thriving ballad tradition. This Scottish scholar, followed by his Danish colleague Svend Grundtvig and the American Francis James Child founded the modern ballad folklore research, since their collections represented the oral folk tradition rather than engaging in search for the “original” folk ballads. The subsequent researchers, influenced by the Child’s ballad scholarship (Phillips Barry, Cecil J. Sharp, Olive D. Campbell, Louise Pound, Henry M. Belden, etc.), continued investigating the American ballad legacy. However, while collecting and encouraging to further collect the surviving ballads they increasingly realized the huge distance between their endeavors and the Child’s collection. The heterogeneous and fragmented nature of the ballads from the oral tradition was increasingly recognized and acknowledged, along with unavoidable impact of the written and printed sources.Barre J. Toelkien, the scholar belonging to even later generation, attempted methodical indexing of the oral ballads belonging to the Child’s collection. Dianne M. Dugaw in turn suggested that assuming the non-written songs, those from the oral tradition, being inherently different from the printed ones had largely affected the way in which folklore researchers perceived and interpreted folksongs. She concluded that differences devised between the written and non-written, between commercial and non-commercial forms were frequently just illusive, since commercial dissemination constituted an integral part of the folksongs development.In view of the confluence of the oral and written traditions surveyed in this article, it is reasonable to conclude that written culture, or rather the popular press, constituted a significant factor affecting the existence of folk ballads in the West; because of obvious reasons, such culture was absent in old-time Lithuania. Contrary to Lithuania, the ballad tradition of the West was nurtured by the written and printed sources. Therefore, the Lithuanian case could present a kind of thought experiment to the folklore researcher, vividly illustrating the plausible ballad tradition development in the West, if it could be unaffected by such phenomena as printed texts in native languages, readily available to the common people.
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Beshyah, Salem A. "The Giant of Tripoli: The Case of Late Recognition and Management of an Extreme Acromegalic Gigantism in Resource-Poor Settings". Journal of Diabetes and Endocrine Practice 05, n. 03 (luglio 2022): 122–25. http://dx.doi.org/10.1055/s-0042-1760393.
Testo completoAbstract (sommario):
Abstract Background There are a few studies from the Middle East and North Africa. Several notable cases of acromegaly and giantism in the west found their way to public life and media. Case History One of the cases is discussed in this article. The case lived between 1943 and 1991. He was one of few individuals in medical history to reach or surpass 8 feet in height. In the 1960s, he reportedly underwent repeated (perhaps 4) pituitary surgery at 17 in Rome, Italy, to halt his growth. A few photos and one short video clip in Italian demonstrate his physical features. He was one of the tallest basketball players ever at 245 cm, though when he featured as a basketball player, he was closer to 239 cm and played for Libya. He was a medical anomaly and the eighteenth tallest person in the history of the world. He was also credited with being the tallest actor in history by appearing in a single Italian fantasy drama movie in 1969. He died in 1991 due to heart disease. Conclusion The case presented in this vignette is depicted in the public domain and is imprinted in the folk memory of the residents of Tripoli, Libya. However, due to its uniqueness, it deserves a place in the regional medical literature.
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TYMOFIEIEVA, Yulia. "TRANSFRONTALITY OF LITERARY IMAGES: EXTRAPOLATION OF THE ITALIAN PUPPET HERO PULCINELLA". 7, n. 7 (26 dicembre 2022): 86–107. http://dx.doi.org/10.26565/2521-6481-2022-7-05.
Testo completoAbstract (sommario):
The article concerns one of the most important characters of national Italian puppet theatre, the marionette Pulcinella, and its influence on the images of folk heroes of puppet and drama theaters, street performances and literary works in European countries. National invariants of this character in the theaters and literatures of Western and Central Europe from the time of the appearance of this character to the beginning of the twentieth century are highlighted. Due to the expansion of economic and political ties, from the beginning of the 17th century, Pulcinella, together with itinerant artists and puppeteers, begins its transition to most European national folk theaters and literature. Depending on the geography of the country, its national character traits and national stereotypes, Pulcinella changes his image, his name, his behavior, and language. However, what is the most important, each national puppet retains both external and internal features of their original predecessor, Pulcinella. Examples provided in the article prove that most of the national invariants of Pulcinella possess his main character trait, that is, a fight against injustice and fierce criticism of authorities. Such characters as the English Punch, the Dutch Pickelgering, the French Polychenelle and Guignol, the German and Austrian Hanswurth, the Spanish and Portuguese Don Cristobal, the Czech Kaszparek and the German Kasperle invariably pursue two main goals: to protect the wronged and to defeat the evil In each of the countries, the characters created on the prototype of Pulcinella, were warmly accepted by the public and became very popular, especially with common people. At the same time, they differed from the original with their national coloring; they became the mouthpiece of national character traits, national ethnic stereotypes. The article seconds the opinion of many literary scholars that the origins the marionette character of Pulcinella can be traced to the Italian folk theater hero of Maccus, mainly because Pulcinella adopts the features of that ancient character's appearance, such as an irregularly shaped head, a large hump on his back, a hooked nose, a large belly and lively shrewd eyes. With small changes and variations, these features of appearance are received not only by Pulcinella, but also by the numerous national invariants of this character in Europe. However, all these national invariants also preserve the typical traits of Pulcinella's character, such as cockiness, cunning, thirst for justice and victory in an argument. In the 19th century, the Pulcinella marionette ‘returns’ to Italy and transforms into the wooden puppet Pinocchio. Carlo Collodi’s novel becomes so popular that it is translated in many countries of the world, and the new characters modelled on Pinocchio, acquire national features, such as Zeppel Kern by the German writer Otto Julius Birbaum. This begins a new round of Pulcinella's influence on the world culture.
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Ostashewski, Marcia, Heather Fitzsimmons Frey e Shaylene Johnson. "Youth-Engaged Art-Based Research in Cape Breton: Transcending Nations, Boundaries and Identities". Jeunesse: Young People, Texts, Cultures 10, n. 2 (dicembre 2018): 100–125. http://dx.doi.org/10.3138/jeunesse.10.2.100.
Testo completoAbstract (sommario):
2017, in conjunction with celebrations of 150 years of Canadian Confederation and with funding from government programs, young people from across Cape Breton Island were invited to participate in a performance creation project to explore narratives and experiences of migration and encounter. Youth (ranging in age from seven to nineteen) from disparate places, including Membertou First Nation (a reserve), Chéticamp (an Acadian, francophone town), Étoile de l’Acadie (a francophone school and community centre in Sydney), and Whitney Pier (a district of Sydney that is home to diverse immigrant cultures, primarily from Barbados, Italy, Newfoundland, Poland, Croatia and Ukraine) all met in their own communities. They listened to elders discuss their own experiences of migration and encounter, and responded by creating new performance pieces grounded in song, dance, film (including new technologies such as virtual reality and 360-degree cameras), spoken word and story. They came together on 22 October 2017 to share their creative work with one another and with public audiences. We examine issues that arose during the creative process and of young participants’ post-process reflections, according to each of the ways in which Vertovec (“Conceiving”) has identified transnationalism. Interpretations of the Cape Breton youths’ own senses of rooted place are positioned in relation to transnational experiences present within their communities. These young people’s expressions of the local (for example, Acadian step dance and Mi’kmaq traditional drumming) morph into expressions of the transnational (for example, hip hop and pop music production); musical expressions use so-called traditional instruments (bagpipes or hand drums), DJ mixing techniques, djembe, Acadian folk music, and Elvis. Problematizing assumptions about what it is to be a Cape Bretoner, and interrogating how migration and resulting encounters have shaped how these young people choose to express themselves, this paper examines how they simultaneously express and contest transnationalism.
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Matulionienė, Elena. "Prototypes and Change of the Ornamental Motifs Decorating the Textile Pockets from the Lithuania Minor". Tautosakos darbai 57 (1 giugno 2019): 127–53. http://dx.doi.org/10.51554/td.2019.28430.
Testo completoAbstract (sommario):
The historical attire of women from the Lithuania Minor (Klaipėda Region) has a characteristic practical detail: a textile pocket tied at the waist, which functionally corresponds to the modern handbag or pocket. Such textile pockets are called delmonai (pl.) and are usually decorated with colorful ornaments. The purpose of this article is introducing the prototypes of the ornamental motifs in terms of intercultural comparison, employing the visual materials collected by the author and historically formed intercultural contacts. While introducing her hypothesis of possible long-term influences, the author presents décor samples from identical or related textile pockets (from the 17th century until the middle of the 20th century), discussing the possibilities of their finding way to the Lithuania Minor. Researching the change occurring in the décor motifs, the author employs comparative analysis of the traditional (from the beginning of the 19th century until 1930s) and modern (from the beginning of the 21st century) textile pockets, still used as part of the national costume of the Lithuania Minor. The origins of several decorative motifs, e.g. the wreath, the crowned musical instrument, and the flower bouquet, are analyzed in more detail. The vegetal ornaments predominate in the décor of the textile pockets from the Lithuania Minor, including blossoms, branches, bouquets, leafs, wreaths and stylized trees. Certain modes of representation have been appropriated by the folk art from professional art or textiles. The most important centers of high fashion emerging in France, Italy, and Germany, exercised certain impact on tendencies occurring in the folk handicraft. Examples of textile pockets worn by the nobility were widely promoted by the periodicals. The surviving samples of embroidery patterns indicate one of the possible sources for the textile pockets’ décor in the Lithuania Minor: namely, the printed sheets with ornamental patterns, used by the nobility and lower social classes alike. Another likely source would be functionally similar needlework by women from the neighboring countries, since textile pockets make part of the national costume there as well. Sea trade created favorable conditions for commercial and cultural interchange between neighbors. The motif of wreath, rather frequently used in the Lithuania Minor, and the occasional motif of the flower bouquet also occur on textile pockets from Pomerania (the border region between Poland and Germany). Ornamentation of the pockets from Bavaria (in Germany) is also rather close in character to the décor of the Lithuania Minor. Such congruities may be determined by several reasons. Firstly, the producers of these textile works could have had interconnections (after the onslaught of devastating plague in Europe, numerous people from Salzburg moved to the fertile but rather wasted out territories of the Lithuania Minor). Secondly, the producers could have used the same original pattern, e.g. the printed sheet. However, although the mutual influence in the needlework décor of the neighboring countries determined by their economic and cultural connections is obvious, the décor of the textile pockets from the Lithuania Minor stands out in terms of its peculiar features (particular colors, modes of décor, etc.).In terms of spreading the regional ethnic culture, the problem of preserving the regional character of the folk art acquires special significance. Although separate parts of the national costumes inevitably change as result of the technical innovations increasingly applied to their production, these costumes should still remain recognizable as a continuation of the folk attire characteristic to the particular region. The patterns of décor used while making the textile pockets nowadays follow to some extent the traditional motifs of floral compositions. Although individual authors tend to create their original compositions, the majority of the textile pockets produced as part of the national costume of the Lithuania Minor still are easily recognizable as belonging to this particular region. The ornamental motifs are not especially distanced from the original ones as well, with embroidered flower bouquets and wreaths still making the majority. However, the motifs of the bouquet placed in a bag and the crowned musical instrument have lost their popularity. Rather than just making part of the national costume of the Lithuania Minor, the textile pockets increasingly appear as part of the modern clothing characterizing its regional peculiarity.
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Muço, Edmond. "Pietro Marubi - Founder of The First Photography Studio in Albania". Pannoniana 7, n. 1 (15 dicembre 2023): 187–95. http://dx.doi.org/10.32903/p.7.1.9.
Testo completoAbstract (sommario):
This article aims to highlight the art of photography in Albania, which began at the end of the 1850s and is associated with the name Pietro Marubi (1834-1903). It deals with the origin of Pietro Marubi, who was Italian from Piacenza. For political reasons, he left Italy, sought refuge in Albania, and settled in the city of Shkodra. The scope is on his extraordinary work, including the founding of the first photography studio in Albania around 1855, which was a bold step at that time. Among his earliest photographs are those of Hamzë Kazazi (1858) and Leonardo de Martino (1859). He became a popular figure in Shkodër, photographing important events with the latest technique, immortalizing historical events such as the connection of Prizren (1878-1881), the uprising of Mirdita that was published in the international press as in the pages of the well-known magazines “La Guerra d'Oriente”, “The illustrated London news”. Pietro Marubi also took the first photograph in Montenegro. In the collection of Sultan Abdul Hamit II, there are photographs with a view of Shkodra or people in folk clothes, as photographed by Pietro Marubi. This proves the great fame that Marubi's photography studio gained in the Ottoman Empire. Pietro Marubi, therefore, brought Shkodra on the level with the first European cities representing the art of photography. The results give an original picture of the role and importance of the photography studio. Marubi and his vision are shown in passing on the profession to his sons. With the act of inheritance of his studio to Kel Kodheli, Marubi would lay the foundations for the continuation of the activity. With Kel Kodheli, the “Marubi Dynasty” was consolidated, where the next generations of photographers were formed, who today make up the collection of the Photo Gallery of the "Marubi" National Museum of Photography. The opening of the national museum “Marubi” in Shkodër, in addition to its extraordinary cultural and historical values, is also at the service of cultural tourism, which is visited by many local and foreign tourists. The article is based on research of the literature and sources published by the Marubi National Museum of Photography and the Library of the Academy of Sciences, as well as international publications and meetings with historians and other researchers. The conclusions provide another important aspect of this work, especially for the generation of young artists educated today who look up to Marubi as a model of inspiration, but also for the general public.
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Лобкова, Г. В. "To the Reader". OPERA MUSICOLOGICA, n. 2022 (18 febbraio 2022): 6–9. http://dx.doi.org/10.26156/om.2022.14.1.001.
Testo completoAbstract (sommario):
В специальном выпуске журнала раскрываются актуальные проблемы современной отечественной и зарубежной этномузыкологии. Настоящее издание включено в программу мероприятий Санкт-Петербургской государственной консерватории имени Н. А. Римского-Корсакова, посвященных Году культурного наследия народов России. В журнале представлены результаты исследований сотрудников, преподавателей, аспирантов, выпускников Московской и Санкт-Петербургской консерваторий, Российской академии музыки имени Гнесиных, Воронежского института искусств, Университета святых Кирилла и Мефодия (Скопье). На протяжении десятилетий в этих образовательных организациях ведется интенсивная деятельность в сфере собирания и изучения музыкального фольклора силами таких структур, как Научный центр народной музыки имени К. В. Квитки, Фольклорно-этнографический центр имени А. М. Мехнецова, Музыкально-этнографический центр имени Е. В. Гиппиуса, Институт фольклора имени Марко Цепенкова. В фондах этих подразделений сосредоточены многие тысячи уникальных экспедиционных аудио- и видеозаписей народных песен, инструментальной музыки, жанров устной словесности, хореографии, которые составляют «золотой запас» нематериального культурного наследия различных народов. В последние годы угроза утраты традиций народной культуры становится все более острой. В связи с этим исследователи столкнулись с необходимостью разработки алгоритмов доступа к документальным источникам, цифровизации фольклорно-этнографических материалов, их включения в сеть Интернет, создания общедоступных порталов, специализированных на различных аспектах актуализации фольклорного наследия. Формы и опыт такой работы в зарубежных странах (Норвегии, Италии, Македонии) представлены в статьях А. Остапенко, И. Тепловой, Р. Величковской. Не менее важной является задача обработки и введения в научный оборот документальных данных, полученных в ходе фольклорных экспедиций разных лет. Такая работа базируется на тщательном изучении каждого образца, требует системного подхода, применения методов типологического исследования, картографирования, историко-стилевой оценки. Конечные цели связаны с созданием фольклорно-этнографического атласа России, с одной стороны, и восстановлением очагов бытования ярких самобытных явлений народной культуры, с другой. В статье И. Никитиной характеризуются мужские певческие традиции Русского Севера; Л. Белогурова и Ю. Журавлева раскрывают особенности свадебных напевов Рязанской области; Г. Сысоева обобщает информацию о весенних песнях южнорусской традиции; исследование А. Косых связано с религиозными песнопениями духоборцев, в основе которых обнаруживаются тексты русских духовных стихов. Тема «фольклор и композитор» представлена в журнале исследованием М. Иоанну и И. Поповой: в статье впервые публикуются подлинные мелодии, которые были использованы Н. Скалкотасом в сюите «36 греческих танцев». В разделе журнала «Документы» перед читателем раскрываются картины истории этномузыкологии. Стенограмма доклада Ф. А. Рубцова, содержание которого затрагивает одну из краеугольных, до сих пор нерешенных научных проблем, позволяет «услышать» живую речь выдающегося ученого. Еще более выразительными по своей эмоциональной достоверности оказываются письма В. И. Харькова и К. В. Квитки, касающиеся чрезвычайно сложных ситуаций их жизни. Публикация документов предваряется статьями Е. Редьковой и Е. Битеряковой, подготовивших рукописи к изданию. A special issue of the magazine reveals current problems of the modern domestic and foreign ethnomusicology. This publication is included in the program of events of the Saint Petersburg Rimsky-Korsakov State Conservatory dedicated to the Year of Cultural Heritage of the Peoples of Russia. The magazine presents the results of the research by employees, teachers, graduate students, graduates of the Moscow and St. Petersburg Conservatories, the Gnesin Russian Academy of Music, the Voronezh Institute of Arts, and the University of Saints Cyril and Methodius (Skopje). These educational organizations have been conducting intensive activity in the field of collecting and studying music folklore for decades, engaging such structures as the Klyment Kvitka Folk Music Research Center, the Anatoliy Mekhnetsov Folklore and Ethnographic Center, the Yevgeniy Gippius Music and Ethnographic Center, and the Marco Tsepenkov Institute of Folklore. The archives of these units contain many thousands of unique expeditionary audio and video recordings of folk songs, instrumental music, genres of oral literature and choreography, which constitute the “golden reserve” of the intangible cultural heritage of various peoples. The threat of loss of traditions of folk culture has become more acute in recent years, which compels researchers to develop algorithms for accessing documentary sources, provide digitalization of folklore and ethnographic materials placing them in the Internet, create public portals specializing in various aspects of actualization of folklore heritage. The forms and experience of such work in foreign countries (Norway, Italy, Macedonia) are presented in articles by A. Ostapenko, I. Teplova, R. Velichkovska. The task of processing and introducing the documentary data obtained during folklore expeditions of different years into scientific circulation is also important. Such work is based on a thorough study of each sample and requires a systematic approach, use of typological research methods, mapping, historical and style assessment. The goal is not only to create a folklore-ethnographic atlas of Russia, but also to restore the forms of existence of original phenomena of the folk culture. Male singing traditions of the Russian North are characterized in the article by I. Nikitina; L. Belogurova and Yu. Zhuravleva describe the features of wedding singing in the Ryazan region; G. Sysoeva summarizes information about spring songs of the South Russian tradition; A. Kosykh studies religious chants of the Dukhobors based on the texts of Russian spiritual verses. The theme “folklore and composer” is presented in the article by M. Ioannou and I. Popova, the genuine melodies used by N. Skalkottas in the suite “36 Greek Dances” being published for the first time. The stages of the history of ethnomusicology are disclosed to the reader in the section “Documents”. The transcript of the report of F. Rubtsov, which covers one of the fundamental, though still unresolved scientific problems, allows you to “hear” a live speech of the outstanding scientist. Even more expressive in their emotional veracity are the letters of V. Khar’kov and K. Kvitka regarding extremely difficult situations of their lives. The section opens with articles by E. Redkova and E. Biteryakova, who prepared manuscripts for publication.
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Di Nuncio, Novella. "CANTI POPOLARI LITUANI: THE FIRST COLLECTION OF LITHUANIAN FOLK POETRY IN ITALIAN". Vertimo studijos 7, n. 7 (5 aprile 2017): 110. http://dx.doi.org/10.15388/vertstud.2014.7.10535.
Testo completoAbstract (sommario):
The essay starts by analyzing an editorial project, the series Poesia popolare indoeuropea (Indo-European Folk Poetry), realized in Italy in 1930 under the guidance of the expert of Slavic Studies Ettore Lo Gatto. The series aimed at a vast audience, with the objective to inform and sensitize the society to ancient and folk literatures of the Indo-European area, a theme not so popular and almost unknown at that time, but also not easy to study, considering the historical period was closed to international cultures. Unfortunately, it was a short experience: the volumes composing the series were just three. The second one, Canti popolari lituani (Lithuanian Folk Songs) by Giuseppe Morici, is the first collection of Lithuanian dainos translated into Italian. This study places a special emphasis on Morici’s work, analyzing its contents and, through its example, reflecting on the issue of translation.
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Akatrini, V. "“VIENNESE” CREATIVE PERIOD IN THE EUSEBIUS MANDYCZEWSKI’S BIOGRAPHY". Aesthetics and Ethics of Pedagogical Action, n. 26 (25 dicembre 2022): 116–29. http://dx.doi.org/10.33989/2226-4051.2022.26.273126.
Testo completoAbstract (sommario):
The article presents the genesis of the Mandyczewski family based on extensive source material; the factors of Eusebius Mandyczewski’s formation as a musician, conductor, and composer are characterized. Attention is focused on the significant influence on his professional development of the well-known church history teacher of Chernivtsi University Eusebius Popovych, music teacher Sydor Vorobkevych, and violin teacher Adalbert Hrimaly. The features of the talent of the future musician in his youth are revealed (he created 82 compositions between the ages of 14 and 17). Emphasis is placed on a significant event – receiving a scholarship at the competition of young talents in Leipzig, which was a significant financial support for his further studies at the University of Vienna. The “Viennese” period of E. Mandyczewski’s creativity, which lasted 54 years, is characterized. In Vienna, he studied German studies, philosophy, literature, art history, musical disciplines; his teachers were music critic Eduard Hanslick, musicologist Martin Gustav Notteb, composer Robert Fuchs. E. Mandyczewski’s professional growth was connected with activities at the Vienna Academy of Music, the Vienna Conservatory; he was the conductor of various choirs and orchestras, archivist and bibliographer of the Viennese “Society of Friends of Music” - one of the significant centers of European musical life.
It was found that during many years of teaching activity, the Maestro trained a whole galaxy of composers, musicologists, teachers, most of whom became stars of the musical world of Austria, Italy, England, America... Among his students are Hans Gall, Karl Behm, Hilarion Verenko, Manolis Calomiris, George Sell, Leone Sinigaglia, Karel Prochazka (senior), Marcian Negria, Joseph Alois Krieps, Julius Patzak, Ferdinand Rebay, Rosario Scalero, Gustav Uwe Yenner, and Arthur Schnabel, Karl Garinger, Ignaz Brühl, Henry Kimball Hadlita, and others. The Austrian press deservedly called the honorary citizen of Vienna E. Mandyczewski “a living musical encyclopedia”. As a theoretician, he wrote many scientific studies on the work of W. Mozart, L. Beethoven, L. Bach, K. Czerny, A. Bruckner, Strauss, etc., compiled a complete edition of the works of J. Haydn, F. Schubert (in 42 volumes), J. Brahms (in 26 volumes). It is emphasized that E. Mandyczewski is the author of 11 Ukrainian choirs, the canon for three voices “And the day goes, and the night goes...” (to the words by T. Shevchenko), music to the lyrics by Yu. Fedkovich “Wake up, Boian!”, “Kobzar’s dawn” etc., vocal works written to the texts of Serbian, Hungarian, Ukrainian, Moldovan folk songs, author’s works written to the texts by Romanian and Moldovan poets M. Eminescu, H. Koshbuk, V. Aleksandr, O. Vlahutse, etc. Research attention is focused on the authorship of vocal works of a secular and spiritual nature, among which the most significant are: “Greek Mass” for solo, choir and orchestra, the cycle “Tuscan Songs”, church works – 12 liturgies, “Cherub” for mixed choir, “Our Father” for two children’s voices, carol “Silent night, holy night”, psalms, etc.
On the basis of primary factual sources, the influence of E. Mandyczewski on the development of musical culture and education in Bukovyna is characterized.
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Satolli, Sara, Simone Agostini e Fernando Calamita. "Behaviour of minor arcuate shapes hosted in curved fold-and-thrust belts: an example from the Northern Apennines (Italy)". Geological Magazine 156, n. 9 (28 gennaio 2019): 1547–64. http://dx.doi.org/10.1017/s0016756818000845.
Testo completoAbstract (sommario):
AbstractArcuate fold-and-thrust belts have been extensively studied in the literature. Less attention, however, has been paid to the characteristics of local-scale arcuate structures, meaning 5–10 km long fold or thrust traces that display map-view curvature. Nevertheless, detailed investigation of small arcuate structures hosted in major arcs can contribute to understanding the pervasiveness of deformation mechanisms. We performed a combined geological and palaeomagnetic study on 21 sites from ac. 60 km2area in the Northern Apennines in order to analyse minor arcs at a kilometric scale. As evidenced by the geological and structural analysis performed on the 21 sites, the fold axial trend changes from N–S to NW–SE in the study area. The comparison with palaeomagnetic results shows the lack of correlation between vertical axis rotations and fold axial trends. As a consequence, the minor arcuate shapes of thrusts and related folds are interpreted as mostly primary features inherited from the geometry of the palaeomargin, represented by pre-orogenic faults, according to a context of inversion tectonics.
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Wołowski, Witold. "Italo Calvino et Jacques Probst : nourriture comme propulseur textuel (déploiement structurel et déploiement diffus d’un thème littéraire)". Romanica Cracoviensia 23, n. 2 (2023): 147–55. http://dx.doi.org/10.4467/20843917rc.23.015.18401.
Testo completoAbstract (sommario):
Italo Calvino and Jacques Probst: food as a textual propulsor (structural deployment and diffuse deployment of a literary theme) This article analizes the theme (motif) of food in Un navire chargé de..., a folk tale rewritten by Italo Calvino and Lise, l’île by Jacques Probst. The Italian tale and the Suiss monologue actually represent two different ways of using food elements in the construction of a text. The first uses the thematic elements in a punctual way, in the crucial moments of the action which correspond to the strong points of the fable; this strategy is called structural deployment of the thematic cluster. The second text, exploiting the absence of food, involves food elements over its entire extent and at different levels of its structure, what we call diffuse deployment (of the thematic cluster).
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Salani, Gian Marco, Michele Lissoni, Gianluca Bianchini, Valentina Brombin, Stefano Natali e Claudio Natali. "Soil Organic Carbon Estimation in Ferrara (Northern Italy) Combining In Situ Geochemical Analyses and Hyperspectral Remote Sensing". Environments 10, n. 10 (4 ottobre 2023): 173. http://dx.doi.org/10.3390/environments10100173.
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This study investigated whether surface soil organic carbon (SOC) content could be estimated using hyperspectral data provided by the Italian Space Agency PRISMA satellite. We collected 100 representative topsoil samples in an area of 30 × 30 Km2 in the province of Ferrara (Northern Italy), estimated their SOC content and other soil properties through thermo-gravimetric analysis, and matched these to the spectra of the sampled areas that were measured by PRISMA on 7 April 2020. A tentative model was created for SOC estimation using ordinary least-squares (OLS) regression and an artificial neural network (ANN). Repeated k-fold cross-validation of the OLS and ANN models yielded R2 values of 0.64 and 0.49, respectively. The performance of the models was inferior to that obtained from the literature using similar modeling techniques in relatively small areas (up to 3 × 3 Km2) and characterized by restricted SOC variability (0.2–2.1 wt%). However, our data were collected over a wider area with high SOC content variability (0.7–9.3 wt%); consequently, significant variations were observed over a spatial scale of just a few meters. Therefore, this work shows the importance of testing remote sensing techniques for SOC measurements in more complex areas than those reported in the existing literature. Furthermore, our study sheds light on the geolocation errors and missing data of PRISMA.
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Maccarrone, Paolo, e Anna Maria Contri. "Integrating Corporate Social Responsibility into Corporate Strategy: The Role of Formal Tools". Sustainability 13, n. 22 (13 novembre 2021): 12551. http://dx.doi.org/10.3390/su132212551.
Testo completoAbstract (sommario):
This paper contributes to the literature debate on the role that formal tools used in the management of CSR activities can play in the integration of CSR into corporate strategy. In particular, the purpose of this research is two-fold: firstly, to investigate if a high degree of formalisation of CSR activities is needed to reach a high degree of integration of CSR into corporate strategy; secondly, to understand what roles CSR formal tools play in this integration process. In order to answer these research questions, eleven case studies of large multinational companies operating in Italy were developed. The results of the empirical analysis show that a high degree of integration is often coupled with intensive use of formalization, with some interesting exceptions. This result can be explained by the active role that almost all CSR formalisation elements play in the integration process of CSR in the overall corporate strategy.
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Yang, Fan, Carlos K. H. Wong, Nan Luo, James Piercy, Rebecca Moon e James Jackson. "Mapping the kidney disease quality of life 36-item short form survey (KDQOL-36) to the EQ-5D-3L and the EQ-5D-5L in patients undergoing dialysis". European Journal of Health Economics 20, n. 8 (23 luglio 2019): 1195–206. http://dx.doi.org/10.1007/s10198-019-01088-5.
Testo completoAbstract (sommario):
Abstract Objectives To develop algorithms mapping the Kidney Disease Quality of Life 36-Item Short Form Survey (KDQOL-36) onto the 3-level EQ-5D questionnaire (EQ-5D-3L) and the 5-level EQ-5D questionnaire (EQ-5D-5L) for patients with end-stage renal disease requiring dialysis. Methods We used data from a cross-sectional study in Europe (France, n = 299; Germany, n = 413; Italy, n = 278; Spain, n = 225) to map onto EQ-5D-3L and data from a cross-sectional study in Singapore (n = 163) to map onto EQ-5D-5L. Direct mapping using linear regression, mixture beta regression and adjusted limited dependent variable mixture models (ALDVMMs) and response mapping using seemingly unrelated ordered probit models were performed. The KDQOL-36 subscale scores, i.e., physical component summary (PCS), mental component summary (MCS), three disease-specific subscales or their average, i.e., kidney disease component summary (KDCS), and age and sex were included as the explanatory variables. Predictive performance was assessed by mean absolute error (MAE) and root mean square error (RMSE) using 10-fold cross-validation. Results Mixture models outperformed linear regression and response mapping. When mapping to EQ-5D-3L, the ALDVMM model was the best-performing one for France, Germany and Spain while beta regression was best for Italy. When mapping to EQ-5D-5L, the ALDVMM model also demonstrated the best predictive performance. Generally, models using KDQOL-36 subscale scores showed better fit than using the KDCS. Conclusions This study adds to the growing literature suggesting the better performance of the mixture models in modelling EQ-5D and produces algorithms to map the KDQOL-36 onto EQ-5D-3L (for France, Germany, Italy, and Spain) and EQ-5D-5L (for Singapore).
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Rizzo, Maria, Yingxin Xu, Ike Iheanacho e Sumeet Panjabi. "A Systematic Literature Review on the Epidemiological Burden in Multiple Myeloma". Blood 124, n. 21 (6 dicembre 2014): 5704. http://dx.doi.org/10.1182/blood.v124.21.5704.5704.
Testo completoAbstract (sommario):
Abstract Objective: Multiple myeloma (MM) is a rare condition, that is, one defined by the European Medicines Agency as affecting no more than 5 in 10,000 people in the EU. It is also the second most common hematologic malignancy. MM is particularly burdensome because most patients eventually relapse and develop refractory disease. To help characterize the epidemiological burden and trends associated with the condition we conducted a systematic literature review to identify published evidence on outcomes including overall incidence and prevalence and survival in patients with relapsed (R) or relapsed and refractory (RR) MM. Methods: We searched the MEDLINE and Embase databases for articles in English published between 2003 and 2013. Identified studies were initially screened using information in the title and abstract, and then by examining the full text using predefined inclusion and exclusion criteria. These criteria specified that to be included, studies had to have reported real-world data on the incidence or prevalence of MM or survival in patients with RMM/RRMM in the following countries: Australia, Austria, Belgium, Brazil, Canada, France, Germany, Italy, Korea, Mexico, the Netherlands, Spain, Sweden, Switzerland, Taiwan, and the UK. To improve generalizability, only studies with a sample size of 100 patients or more were included. Results: The review identified a total of 1,632 studies across MEDLINE and Embase. Following screening, 22 studies met the predefined selection criteria (as described above in the Methods section). Most studies (n=21) were retrospective in design, of which 10 studies reported on incidence and/or prevalence outcomes and 12 on survival. Specifically, incidence was reported for populations in Brazil (n=1), Canada (n=1), France (n=1), Germany (n=1), Italy (n=1), Korea (n=3), and Taiwan (n=2); two of these studies also reported prevalence data for populations in Brazil and Korea. The studies on survival included patients who received a range of 1 to 9 previous treatments for MM and were conducted in Canada (n=1), France (n=1), Germany (n=2), Italy (n=4), South Korea (n=1), Spain (n=1) and the UK (n=2). No published studies for any of the outcomes of interest were identified for populations in the following countries: Australia, Austria, Belgium, Mexico, the Netherlands, Sweden, or Switzerland. In the studies that reported a crude (i.e., age-unadjusted) incidence for MM, the incidence ranged from around 1.4 to 2.1 cases per 100,000 population per year. Of note, the incidence was found to have risen in recent decades, from 1.0 case per 100,000 population in 1999 to 1.5 cases per 100,000 in 2009 in Korea (a rise of 4.1% each year; p < 0.05) and from 0.36 cases per 100,000 in the period from 1979 to 1983 to 1.6 cases per 100,000 in 2009 in Taiwan (a 4.4-fold increase between these years). The prevalence of MM was 5.7 per 100,000 population from October 2009 to March 2010 in Brazil and 5.5 per 100,000 population in January 2010 in Korea. Among patients who received chemotherapy regimens to manage RMM/RRMM, overall survival ranged from 12.4 months in those treated with bendamustine (following a median of 4 previous lines of therapy that included alkylators, steroids, an immunomodulatory drug, and bortezomib) to 26.2 months for those treated with thalidomide with or without the use of salvage therapy (following a median of 1 prior therapy). One study that explored predictors of overall survival found that this outcome was significantly worse in patients who previously receive more lines of treatment (3 or above) compared with those who received fewer lines of treatment (18.1 months compared with 38.9 months, respectively; p = 0.019). Conclusions: Recently published data on key epidemiological outcomes in MM are limited, even for several industrialized countries, perhaps reflecting the condition’s rare-disease status. The available evidence suggests that the incidence of MM has been rising in recent decades, though the overall incidence remains low enough for MM to still be considered a rare disease. Despite the range of chemotherapeutic options that are currently available, survival in patients who have RMM/RRMM is poor and worsens with each relapse and with increasing number of prior lines of treatment. This pattern of decreasing survival in later lines of treatment suggests the need for additional therapies to improve outcomes in MM and RMM/RRMM. Disclosures Rizzo: Onyx Pharmaceuticals, Inc., an Amgen subsidiary: Consultancy; Evidera: Employment. Xu:Onyx Pharmaceuticals, Inc., an Amgen subsidiary: Consultancy; Evidera: Employment. Iheanacho:Onyx Pharmaceuticals, Inc., an Amgen subsidiary: Consultancy; Evidera: Employment. Panjabi:Onyx Pharmaceuticals, Inc., an Amgen subsidiary: Employment, Equity Ownership.
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Quintiliani, Andrea. "FINANCIAL CRISIS AND LOCAL BANKS: A REVIEW OF BANK-FIRM RELATIONSHIPS IN ITALY". Corporate Ownership and Control 14, n. 3 (2017): 249–58. http://dx.doi.org/10.22495/cocv14i3c1art10.
Testo completoAbstract (sommario):
This paper focuses on bank-firm relationship in an economic deeply changing environment. The objectives of the paper are two-fold: to understand, compared to the overall banking system, if the lending activities and economic-financial performances of Italian local banks have changed after the outbreak of the financial crisis; and to understand what are the conditions that allow to develop a model of a local bank capable of supporting the development routes of SMEs, by an appropriate risk/return profile. In order to answer the first research question, the paper presented an empirical analysis, covering the period 2007-2011, of Italian Cooperative Credit Banks (a particular category of local banks) compared with the system of bank groups with operability spread over much of the Italian territory and not. The empirical comparative analysis has the aim to see the effects of the crisis on the relationship bank-firm through the reading of the impact on the dynamics of lending and on the profiles of structure, riskiness, profitability and efficiency of the banks under examination. In order to provide an answer to the second research question, the paper provides some insight of evolutionary nature reflection in the bank-firm relationship. In accordance with the doctrinal postulates of the relationship lending the empirical analysis shows how the financial then real crisis has not induced Cooperative Credit Banks to restrict credit to local firms. The survey evidences have however highlighted some critical elements that are reflected inevitably on the local bank’s risk-return profile. Based only on quantitative data of statement, the empirical analysis represents a limit in this kind of research. This paper is useful to stimulate the debate of experts as well as to focus on the studies of local banks in particular in the light of their anti-cyclic role. Even if abounding in subjects about local banks and relationship lending literature faces only marginally the effects of global crisis on business profiles of local banks.
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Costa, Mario, Jessica Chicco, Chiara Invernizzi, Simone Teloni e Pietro Paolo Pierantoni. "Plio–Quaternary Structural Evolution of the Outer Sector of the Marche Apennines South of the Conero Promontory, Italy". Geosciences 11, n. 5 (24 aprile 2021): 184. http://dx.doi.org/10.3390/geosciences11050184.
Testo completoAbstract (sommario):
Some new results and preliminary remarks about the Plio–Quaternary structural and evolutionary characteristics of the outer Marche Apennines south in the Conero promontory are presented in this study. The present analysis is based on several subsurface seismic reflection profiles and well data, kindly provided by ENI S.p.A. and available on the VIDEPI list, together with surface geologic–stratigraphic knowledge of Plio–Quaternary evolution from the literature. Examples of negative vs. positive reactivation of inherited structures in fold and thrust belts are highlighted. Here, we present an example from the external domain of the Marche Apennines, which displays interesting reactivation examples from the subsurface geology explored. The study area shows significant evolutionary differences with respect to the northern sector of the Marche region previously investigated by the same research group. The areal distribution of the main structures changes north and south of the ENE–WSW oriented discontinuity close to the Conero promontory. Based on the old tripartite classification of the Pliocene, the results of this work suggest a strong differential subsidence with extension occurring during the Early Pliocene and principal compressive deformation starting from the Middle Pliocene and decreasing or ceasing during the Quaternary. The main structure in this area is the NNW–SSE Coastal Structure, which is composed of E-vergent shallow thrusts and high-angle deep-seated normal faults underneath. An important right-lateral strike–slip component along this feature is also suggested, which is compatible with the principal NNE–SSW shortening direction. As mentioned, the area is largely characterized by tectonic inversion. Starting from Middle Pliocene, most of the Early Pliocene normal faults became E-vergent thrusts.
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Beneduce, Roberto. "Recent Italian Literature in Medical Anthropology (1989-92): Medicine e magie: Le tradizioni popolari in Italia (Medicine and Magic: Folk Traditions in Italy) . Tullio Seppilli. ; Medecine traditionnelle: Acteurs, itineraires therapeutiques . Piero Coppo, Arouna Keita. ; Profeti in citta: Etnografia di quattro chiese indipendenti del Ghana (Town Prophets: Ethnography of Four Independent Churches in Ghana) . Pino Schirripa. ; Itinerari delle emozioni: Corpo e identita femminile nel Sannio campano (Itineraries of Emotions: Women's Bodies and Identity in Sannio, Campania) . Mariella Pandolfi. ; Sortilegio e delirio: Psicopatologia dell'emigrazione in prospettiva transculturale (Sorcery and Delusion: The Psychopathology of Emigration in Transcultural Perspective . Michele Risso, Wolfang Boker." Medical Anthropology Quarterly 8, n. 2 (giugno 1994): 221–26. http://dx.doi.org/10.1525/maq.1994.8.2.02a00080.
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Grosso, S., G. Mason, E. Ortalda e M. Scortichini. "Brenneria salicis Associated with Watermark Disease Symptoms on Salix alba in Italy". Plant Disease 95, n. 6 (giugno 2011): 772. http://dx.doi.org/10.1094/pdis-11-10-0781.
Testo completoAbstract (sommario):
From 1999 to 2010, withering of white willow was observed on trees growing along roads or irrigation canals in Torino, Alessandria, and Vercelli provinces of Italy, with incidence varying from 15, 25, and 30%, respectively. In spring and autumn 2008, six samples from withering branches with bark cankers were collected. On the bark surface near the cankers, iridescent traces of dried ooze were found. Tissues immediately below the cankers were dark with water-soaked, olive-colored edges. In some cases, the xylem appeared affected. Small fragments taken from the affected tissue on both edges of bark alterations and darkened vessels were crushed into mortars with sterile saline. Ten-fold serial dilutions (10–1, 10–2) were also performed. Aliquots of 0.1 ml were plated on nutrient agar and incubated at 25°C for 4 days. Bacterial colonies were ivory to white, circular, and bright, with a diameter of ~2 mm. Isolates were negative for Gram staining, presence of arginine dehydrolase, oxidase, phenylalanine deaminase, urease, hydrolysis of gelatin and starch, nitrate reduction, acidity from d-arabinose, cellobiose, lactose, maltose, trehalose, xylose, and pectinolytic activity on potato slices; positive for the presence of catalase and levan, fermentative metabolism of glucose, acid production from aesculin, l-arabinose, dextrose, d-galactose, inositol, d-mannitol, α-methylglucoside, raffinose, salicin and sucrose, H2S production from cysteine, and bright yellow pigment production on autoclaved potato tissue. They were not fluorescent on King's medium B and did not induce hypersensitivity reaction on tobacco leaf. Similar results were obtained with Brenneria salicis control strain, LMG 6089, except for acid production from α-methylglucoside (negative) and l-arabinose (negative). Acid production from α-methylglucoside has been reported for the Japanese strains of B. salicis, which do not produce acidity from inositol (4). Genomic DNA was extracted (1) from three isolates, and PCR reactions were performed with Es1A and Es4B primers (2) that amplify a 553-bp fragment from the 16S rDNA of B. salicis. The isolates showed a PCR product of expected size, like the positive control LMB 6089. On the basis of colony features, biochemical tests, and the PCR assay, we conclude that the isolates belong to B. salicis, a pathogen reported in Belgium, Germany, Great Britain, the Netherlands, Hungary, Japan, and New Zealand (2,3) but, as well as watermark disease symptoms, never previously reported in Italy. In summer 2009, pathogenicity tests were performed by inoculating young, white willow plants with B. salicis suspensions of ~1 to 2 × 109 CFU/ml placed with a syringe at the intersection of 1-year-old branches on the trunk. However, a year later, no symptoms of disease have been noted on the inoculated plants. According to the literature, pathogenicity tests rarely lead to the expected results because the bacterium can survive for many years in latent form, breaking out only when proper environmental conditions occur (3). Also the tests with B. salicis LMG 6089 gave negative results. Further investigation is necessary to clarify the relationships between this bacterium and the environment in causing withering of white willows in Piedmont. References: (1) W. P. Chen and T. T. Kuo. Nucleic Acids Res. 21:2260, 1993. (2) L. Hauben et al. Appl. Environ. Microbiol. 64:3966, 1998. (3) M. Maes et al. Environ. Microbiol. 11:1453, 2009. (4) Y. Sakamoto et al. Plant Pathol. 48:613, 1999.
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Konyaeva, O. I., N. Yu Kulbachevskaya, V. A. Chaley, N. P. Ermakova, I. B. Merkulova, T. V. Abramova e I. S. Kasatkina. "Equitoxicity of domestic hydroxycarbamide and reference drug hydrea in rats". Russian Journal of Biotherapy 18, n. 1 (19 aprile 2019): 80–86. http://dx.doi.org/10.17650/1726-9784-2019-18-1-80-86.
Testo completoAbstract (sommario):
Introduction . The appearance of high-quality and effective generics can significantly reduce the cost of health care for the drug supply of the population of Russia. According to expert estimates, the cost of treatment of cancer patients with generics of domestic can be 30– 40 % cheaper as compared to the original drugs. In Russia the pharmaceutical production company “Ozon” created by the domestic analogue of the original anticancer drug hydrea – hydroxycarbamide.Objective: comparative study of chronic toxicity of the drug hydroxycarbamide (“Ozon”, Russia) and registered reference drug hydrea (Corden Pharma Latina S. p. A., Italy) on rats.Materials and methods . A comparative study of the toxicity of drugs was carried out on 70 non-inbred white male rats weighing 220– 250 g obtained from the accredited laboratory animal nursery of LLC “Krolinfo”. Both drugs were administered in parallel daily orally 5-fold in 3 doses. As a solvent, 1 % starch paste was used. Doses were calculated according to the literature data on the basis of maximum tolerated dose. Standard methods of evaluation of chronic toxicity of drugs in rats were used.Results . The obtained data on chronic toxicity of the compared forms of the domestic drug hydroxycarbamide and the reference drug hydrea do not differ significantly in terms of quantitative and qualitative toxicity (lethality, biomarkers of toxicity, morphometry of organs). Conclusion . The compared generic and commercial preparations are practically equitoxic by 5 times oral administration to rats.
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Leitão, João, Dina Pereira e Sónia de Brito. "Inbound and Outbound Practices of Open Innovation and Eco-Innovation: Contrasting Bioeconomy and Non-Bioeconomy Firms". Journal of Open Innovation: Technology, Market, and Complexity 6, n. 4 (13 novembre 2020): 145. http://dx.doi.org/10.3390/joitmc6040145.
Testo completoAbstract (sommario):
Generating innovation with environmental impact is crucial for firms to achieve sustainable eco-innovative performance. In the reference literature on open innovation, gaps still persist at the level of scarce and limited knowledge on the use of knowledge sources and flows, for the purpose of strengthening the eco-innovative performance of the bioeconomy sector. To address these caveats, this study analyses the effects of open innovation on eco-innovation, based on inbound and outbound support practices. Specifically, it aims to analyse the effects of these practices on the eco-innovative performance of bioeconomy and non-bioeconomy firms, using secondary data gathered from the Community Innovation Survey—CIS 2010 for a sample of moderately innovative countries, namely Slovakia, Spain, Hungary, Italy, Portugal and the Czech Republic. The conceptual model proposed is tested using multivariate tobit regression models, in order to ensure the accuracy and reliability required to validate empirical tests. Overall, the empirical evidence allows the conclusion that inbound and outbound practices and public policies have a positive and significant influence on the eco-innovative performance of the firms studied. The contribution provided is two-fold: (i) in theoretical terms, an operational model of open innovation inbound and outbound practices is extended, crossing financial flows and innovation directions; and (ii) in empirical terms, new light is shed on the still limited knowledge about the positive and significant effects of open innovation outbound practices on the eco-innovative performance of companies belonging to a global strategic sector—that is, the bioeconomy sector, which has renewed strategic importance in the face of global climate change.
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Zampieri, Dario, Paola Vannoli e Pierfrancesco Burrato. "Geodynamic and seismotectonic model of a long-lived transverse structure: The Schio-Vicenza Fault System (NE Italy)". Solid Earth 12, n. 8 (26 agosto 2021): 1967–86. http://dx.doi.org/10.5194/se-12-1967-2021.
Testo completoAbstract (sommario):
Abstract. We make a thorough review of geological and seismological data on the long-lived Schio-Vicenza Fault System (SVFS) in northern Italy and present for it a geodynamic and seismotectonic interpretation. The SVFS is a major and high-angle structure transverse to the mean trend of the eastern Southern Alps fold-and-thrust belt, and the knowledge of this structure is deeply rooted in the geological literature and spans more than a century and a half. The main fault of the SVFS is the Schio-Vicenza Fault (SVF), which has a significant imprint in the landscape across the eastern Southern Alps and the Veneto-Friuli foreland. The SVF can be divided into a northern segment, extending into the chain north of Schio and mapped up to the Adige Valley, and a southern one, coinciding with the SVF proper. The latter segment borders to the east the Lessini Mountains, Berici Mountains and Euganei Hills block, separating this foreland structural high from the Veneto-Friuli foreland, and continues southeastward beneath the recent sediments of the plain via the blind Conselve–Pomposa fault. The structures forming the SVFS have been active with different tectonic phases and different styles of faulting at least since the Mesozoic, with a long-term dip-slip component of faulting well defined and, on the contrary, the horizontal component of the movement not being well constrained. The SVFS interrupts the continuity of the eastern Southern Alps thrust fronts in the Veneto sector, suggesting that it played a passive role in controlling the geometry of the active thrust belt and possibly the current distribution of seismic release. As a whole, apart from moderate seismicity along the northern segment and few geological observations along the southern one, there is little evidence to constrain the recent activity of the SVFS. In this context, the SVFS, and specifically its SVF strand, has accommodated a different amount of shortening of adjacent domains of the Adriatic (Dolomites) indenter by internal deformation produced by lateral variation in strength, related to Permian–Mesozoic tectonic structures and paleogeographic domains. The review of the historical and instrumental seismicity along the SVFS shows that it does not appear to have generated large earthquakes during the last few hundred years. The moderate seismicity points to a dextral strike-slip activity, which is also corroborated by the field analysis of antithetic Riedel structures of the fault cropping out along the northern segment. Conversely, the southern segment shows geological evidence of sinistral strike-slip activity. The apparently conflicting geological and seismological data can be reconciled considering the faulting style of the southern segment as driven by the indentation of the Adriatic plate, while the opposite style along the northern segment can be explained in a sinistral opening “zipper” model, where intersecting pairs of simultaneously active faults with a different sense of shear merge into a single fault system.
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Duarte, D., F. Nex, N. Kerle e G. Vosselman. "TOWARDS A MORE EFFICIENT DETECTION OF EARTHQUAKE INDUCED FAÇADE DAMAGES USING OBLIQUE UAV IMAGERY". ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W6 (23 agosto 2017): 93–100. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w6-93-2017.
Testo completoAbstract (sommario):
Urban search and rescue (USaR) teams require a fast and thorough building damage assessment, to focus their rescue efforts accordingly. Unmanned aerial vehicles (UAV) are able to capture relevant data in a short time frame and survey otherwise inaccessible areas after a disaster, and have thus been identified as useful when coupled with RGB cameras for façade damage detection. Existing literature focuses on the extraction of 3D and/or image features as cues for damage. However, little attention has been given to the efficiency of the proposed methods which hinders its use in an urban search and rescue context. The framework proposed in this paper aims at a more efficient façade damage detection using UAV multi-view imagery. This was achieved directing all damage classification computations only to the image regions containing the façades, hence discarding the irrelevant areas of the acquired images and consequently reducing the time needed for such task. To accomplish this, a three-step approach is proposed: i) building extraction from the sparse point cloud computed from the nadir images collected in an initial flight; ii) use of the latter as proxy for façade location in the oblique images captured in subsequent flights, and iii) selection of the façade image regions to be fed to a damage classification routine. The results show that the proposed framework successfully reduces the extracted façade image regions to be assessed for damage 6 fold, hence increasing the efficiency of subsequent damage detection routines. The framework was tested on a set of UAV multi-view images over a neighborhood of the city of L’Aquila, Italy, affected in 2009 by an earthquake.
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Vutcovici Nicolae, Maria, Mei Dong, Teraneh Z. Jhaveri, Laura De Benedetti, Hanane Khoury, Lee Stern, Mellissa Williamson et al. "Incidence of drug-induced myelosuppression and associated adverse events (AEs), quality of life (QOL), and medical resource use (MRU) in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)." Journal of Clinical Oncology 41, n. 16_suppl (1 giugno 2023): e19072-e19072. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e19072.
Testo completoAbstract (sommario):
e19072 Background: This study aimed to provide a comprehensive overview of the evidence available on drug-induced myelosuppression in patients with MDS or AML. Methods: A systematic literature review (SLR) was conducted using MEDLINE, Embase, and Cochrane to identify studies published 2002-2022 explicitly targeting drug-induced myelosuppression with current and emerging treatments used for MDS and/or AML (venetoclax [VEN], azacitidine [AZA], magrolimab, sabatolimab, decitabine [DEC], cedazuridine, lenalidomide [LEN], low-dose cytarabine [LDAC], intensive chemotherapy [IC]) in terms of drug-induced AEs, treatment discontinuation, QOL, and MRU. Article selection was based on predefined eligibility criteria (PICO+ framework), with a focus on specific geographic regions (USA, UK, Spain, Italy, France, Germany). Results: A total of 48 studies reporting on VEN, AZA, DEC, LEN, LDAC, and IC based regimens met the inclusion criteria. In MDS populations, myelotoxicity was reported in all blood cell lineages in association with AZA, DEC, and LEN monotherapies. In AML populations, myelosuppression was reported in all blood cell lineages in association with all regimens except LEN. In general, the reported incidence of myelosuppressive AEs was higher in studies published prior to 2010 and in studies of patients with AML or MDS who had received prior treatments vs more recent studies (2018-2022) and studies of treatment-naive patients, respectively. Differences observed between the two time periods might be explained by improved supportive care (AEs prophylaxis and management). In treatment-naive AML populations, the incidence of any-grade febrile neutropenia, leukopenia, and anemia was up to 3-fold higher with AZA combination therapy vs monotherapy, and the incidence of any-grade neutropenia and febrile neutropenia was 2-fold higher with LDAC combination regimens vs monotherapy, suggestive of an additive effect. The most common reasons for treatment discontinuation were AEs and disease progression. QOL significantly improved with AZA monotherapy; however, hematologic improvement was not explicitly mentioned as the main driver. There were no data on combination therapies to indicate whether the improvement in QOL compensated for the added drug-induced AEs. The few studies that reported on the impact of myelosuppression on MRU did not provide conclusive results. Conclusions: This SLR suggests that combining ≥2 myelosuppressive drugs may result in increased toxicity; however, the lack of evidence on the impact of myelotoxicity on QOL and MRU with ≥2 myelosuppressive drugs limits informed decision-making in routine clinical practice. Further research is needed to explore the impact of drug-induced myelosuppression in patients with MDS or AML.
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Pugh, Sarah, Wilhelm Erber, Andreas Pilz e Heinz-Josef Schmitt. "758. Epidemiology of Tick-Borne Encephalitis (TBE): A Traveler′s Perspective". Open Forum Infectious Diseases 7, Supplement_1 (1 ottobre 2020): S426. http://dx.doi.org/10.1093/ofid/ofaa439.948.
Testo completoAbstract (sommario):
Abstract Background Tick-borne Encephalitis (TBE) is a CNS infection caused by the TBE virus (TBEV), transmitted by ticks or by ingestions of unpasteurized dairy products. Persisting sequelae occur in up to 50% of patients and case fatality rates are 0.4-6% (up to 20% in Russia). There is no specific treatment, but prevention exists. New areas of TBEV circulation were recently identified. Here the current distribution of the TBEV by the end of 2019 is summarized. Methods Data were obtained from solicitation of local expert data from countries in Europe and Asia on TBEV isolation, type of surveillance/reporting, past/current case counts, and vaccine uptake, supplemented by literature searches. Countries were classified as suggested by the European Centers for Disease Prevention and Control (ECDC) as TBE- “predisposed” (competent ticks present), “imperiled” (TBEV isolated), “affected” (sporadic autochthonous cases) or “endemic” (annually autochthonous cases). Results TBE has now been diagnosed in Eurasia from the United Kingdom, Norway and France in the west, northern Italy in the south, central/eastern Europe, Russia, China on to Japan in the east. “New endemic” countries in the last five years include the United Kingdom, the Netherlands, as well as “new endemic regions”, e.g. in France, Norway, Germany, Finland and Poland. Six countries are considered as predisposed only, three as imperiled, five as affected and 29 as endemic. Misclassification is likely as some countries have no testing (no test), incomplete testing and/or underreporting. Conclusion The main considerations of TBEV risk for oversea travelers to Eurasia are: 1) the exact region and terrain within a country; 2) the planned type of (outdoor) activity; 3) the reliability of within country TBEV surveillance. TBE incidences per region may fluctuate log-fold over just a few years and low reported case counts may reflect a lack of testing, and/or preventive measures including vaccine uptake, and underreporting. As the incidence of TBE is unpredictable, prevention measures should be considered for any person traveling or residing in a recognized TBE “risk area”. Disclosures Sarah Pugh, PhD, Pfizer (Employee, Shareholder) Wilhelm Erber, PhD, Pfizer (Employee, Shareholder) Andreas Pilz, PhD, Pfizer (Employee, Shareholder) Heinz-Josef Schmitt, MD, Pfizer (Employee, Shareholder)
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Kumar, Mukta, e William Keough. "Pneumocystis Jirovecii Pneumonia as A Cause of Acute Respiratory Failure In Childhood Acute Lymphoblastic Leukemia". Blood 116, n. 21 (19 novembre 2010): 4876. http://dx.doi.org/10.1182/blood.v116.21.4876.4876.
Testo completoAbstract (sommario):
Abstract Abstract 4876 Pneumocystis jirovecii is an opportunistic pathogen responsible for severe pneumonia in immunocompromised patients. Management of this pneumonia remains a major challenge for all physicians caring for immunosuppressed patients. The prognosis of Pneumocystis jirovecii pneumonia (PCP) with acute respiratory failure is traditionally known to be poor. We report a case of PCP in a child with recently diagnosed childhood Precursor B cell Acute Lymphoblastic Leukemia (ALL). Course was complicated with acute respiratory failure showing hypoxemia, respiratory failure requiring intubation and reduced compliance resembling ARDS. Our Patient, 8 weeks into chemotherapy for newly diagnosed ALL, presented with high grade fevers and poor activity. Patient was admitted 3 weeks prior for Bacillus cereus bacteremia. Additionally the patient had been on broad spectrum antibiotics on 2 occasions for febrile neutropenia episodes within the past 2 weeks. Patient had minimal respiratory symptoms at this presentation and recovered from pancytopenia at the time of this presentation. CT scans and chest x-ray (Figures 1 and 2) showed diffuse marked ground glass opacities with dependent consolidation in the lungs. On day 3 of admission, bronchoalveolar lavage (BAL) was preformed and empiric trimethoprim-sulfamethoxazole was initiated in addition to broad spectrum antibacterial, antifungal and antiviral medications. Within 24 hours, patient rapidly deteriorated with significant respiratory distress and hypoxemia requiring intubation. Clinical and radiologic findings were suggestive of ARDS. Patient required significant ventilatory support, fluid restriction, diuretics, and steroids. PCR testing of BAL fluid was reported as positive for Pneumocystis jirovecii. By hospital day 6 the patient was still requiring a fair amount of respiratory support. Corticosteroids had been added but concern amongst some members of the team surrounded possible lack of efficacy of trimethoprim-sulfamethoxazole. Review of published case reports suggested that addition of caspofungin provided salvage therapy in cases where trimethoprim-sulfamethoxazole was believed to be suboptimal. Caspofungin was added to this patient's treatment. However, liver trans-aminases experienced a 2–3 fold increase within 72 hours after initiating caspofungin. Caspofungin was withdrawn but the patient's condition gradually improved and was extubated 7 days later. Also of note, there have been wide spread regional and national shortages of intravenous trimethoprim-sulfamethoxazole preparations. We were forced to convert to oral therapy several days after extubation. The patient continued to improve and had no signs of complications or increased morbidity from this conversion; however, this was a continued concern during his treatment. A Pub Med review of the literature reveals very little failure of trimethoprim-sulfamethoxazole prophylaxis in the non-HIV immunocompromised population. Further, studies in Denmark, Italy, and the UK reveal that trimethoprim-sulfamethoxazole prophylaxis in children with ALL also decreases the number of febrile and bacteremic incidents. Trimethoprim-sulfamethoxazole also has advantages over other prophylactic choices against Pneumocystis jirovecii with fewer side effects such as methemoglobinemia induced by dapsone for example. Other studies from the UK, US, and Denmark stress that the early diagnosis and treatment with appropriate antimicrobials and possibly corticosteroids has a better outcome in this frequently fatal complication of immunosupressed patients. This case stresses the need for continued patient education regarding adherence to prophylactic regimens, early diagnosis and suspicion of opportunistic organisms such as Pneumocystis jirovecii, and prompt diagnosis and treatment of the same.Figure 1.Ground Glass Opacities on CT ChestFigure 1. Ground Glass Opacities on CT ChestFigure 2.Chest x-ray infiltratesFigure 2. Chest x-ray infiltrates Disclosures: No relevant conflicts of interest to declare.
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Hatzinicolaou, Stamatia-Lydia, Danai Palaiologou, Antonios G. Antoniadis, Georgios Papanikolaou, Nikolaos Sakellaropoulos, Gerassimos A. Pangalis, John Meletis e Antonios Kattamis. "A Study of the Hereditary Hyperferritinemia Cataract Syndrome in Patients of Greek Origin". Blood 120, n. 21 (16 novembre 2012): 3205. http://dx.doi.org/10.1182/blood.v120.21.3205.3205.
Testo completoAbstract (sommario):
Abstract Abstract 3205 Background: Hereditary hyperferritinemia cataract syndrome (HHCS) is an autosomal dominant disorder characterized by elevated serum L-ferritin and early onset bilateral cataracts. The syndrome, first described in Italy and France in 1995, is caused by mutations in the iron responsive element (IRE) of the L-ferritin gene (FTL-ferritin light chain) on chromosome 19q13.3. The conformational changes in the mutated IRE disrupt the binding of the iron regulatory proteins (IRPs) to the IRE, resulting in loss of the posttranscriptional control in L-ferritin synthesis. L-ferritin is constitutively expressed in tissues, irrespective of cellular iron status and without otherwise disrupting cellular iron metabolism. Despite the five to twenty-fold increase in serum L-ferritin, there is no clinical or laboratory evidence of iron overload. Serum iron and transferrin saturation remain within normal limits. Visual impairment and early cataract formation is the only clinical symptom of HHCS, with lens replacement being the only treatment needed. Extensive and invasive investigations in the undiagnosed hyperfferitinemic patient, as well as unnecessary treatment with phlebotomies, can be avoided with awareness of the syndrome, leading to the correct clinical and molecular diagnosis. Aim: HHCS has been previously reported in a limited number of patients of Greek origin, with the study of three unrelated families in Greece. Papanikolaou et al. (Blood Cells Mol Dis. 2006) detected the C39>G mutation in the IRE of the FTL in all affected individuals. Our aim was to further investigate the syndrome within the Greek population, both phenotypically and genetically. Methods: We investigated 81 patients with undiagnosed hyperferritinemia referred to the Hepatology Outpatients Clinic of the 1st Department of Internal Medicine at “Laikon” General Hospital in Athens. For all patients full medical history and clinical examination (including ophthalmological evaluation) was performed, and laboratory investigations were tailored accordingly. Where indicated from the medical history and laboratory findings, molecular analysis for mutations in the IRE of the FTL was performed using direct DNA sequencing. Results: From the total of 81 patients referred for undiagnosed hyperferritinemia, 18 unrelated subjects had a positive history of cataract and elevated ferritin. In those subjects ferritin levels ranged from 600 to 2070μg/L (normal values: 12–160μg/L). Serum iron was within normal limits and transferrin saturation ranged from 9 to 40%. Cataract diagnosis was reported as early as 5 years of age and 8 out of the 18 subjects had undergone surgery for lens replacement at the time of referral. From the 18 subjects that were screened for mutations in the IRE of the FTL, mutations were detected in 12 unrelated subjects. Ten out of the 12 individuals were positive for the previously described C39>G point mutation. The other two subjects were found to carry the A40>G mutation. The A40>G mutation has been described in the literature as part of the spectrum of mutations causing HHCS (Beaumont et al, Nat. Genet. 1995), however it has not up to now been reported in subjects of Greek origin. From the 12 subjects positive for either mutation, 8 reported positive family history for either early onset cataracts, hyperferritinemia or both. Where possible, clinical, laboratory and molecular investigations were extended to other members of these families. A total of 40 subjects from the members of the studied families fulfilled the clinical criteria of HHCS. Genetic testing was performed in 12 of them, revealing 11 subjects heterozygous for the C39>G mutation and 1 heterozygous for the A40>G mutation. Conclusion: HHCS is a non-iron loading, rare disorder that should be considered in all patients with unexplained hyperferritinemia, in order to avoid unnecessary investigations, potentially hazardous treatment and confer reassurance to the patient. Our findings contribute to the clinical and molecular characterization of the syndrome and extend the study of the disorder in the Greek population. Disclosures: No relevant conflicts of interest to declare.
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Di Stefano, Valeria, Barbara Gianesin, Matteo Bertini, Martina Culcasi, Anna Rita Denotti, Giorgio Derchi, Marianna Giuditta et al. "Atrial Fibrillation Prevalence and Its Management in Transfusion-Dependent Thalassemias: The Fathal Study". Blood 142, Supplement 1 (28 novembre 2023): 2472. http://dx.doi.org/10.1182/blood-2023-182773.
Testo completoAbstract (sommario):
Atrial fibrillation (AF) represents an emerging issue in the thalassemia population related to increased life expectancy. However, data on AF in these patients are limited, and the current management is based on the guidelines for the general population. Nevertheless, AF in these patients has distinctive features that could require specific management. We conducted a multicentric retrospective study supported by the Italian Society of Thalassemia and Hemoglobinopathies (SITE) to elucidate the prevalence of AF in transfusion-dependent thalassemia (TDT) adults in Italy and to study its management, particularly the use of transcatheter ablation and anticoagulation management. Patients followed between June 1, 2003 and May 31, 2023 with a diagnosis of alpha- or beta-transfusion-dependent thalassemia with at least one episode of AF were included in the study. Clinical data of patients have been retrospectively collected with dedicated digital case report form (CRF). So far, 3 centers (Cagliari, Ferrara, Milano) have participated in the study. Eight-hundred-sixty-one adult TDT patients are regularly followed in the participating centers. Data from 130 adult TDT with AF were included. At enrollment, 119 patients were alive (71 males, 60%), the mean age at enrollment was 51.9 years, and 71% were splenectomized. Almost all (98%) had beta-thalassemia, of which 20% had thalassemia intermedia and became transfusion dependent during their life. The mean age at the first AF episode was 39.7 yr. Overall, AF prevalence in TDT was 13.8%, with a significant rise above the age of 50 (age 51-65: prevalence 26.4%, age>65 33.3%), differently from the general population in which the prevalence is 2-4%, and patients are older. As in the general population, prevalence was higher in males (18.2% vs 10.2%). Among the known risk factors for AF, the most frequent were diabetes (16%, n=111) and previous heart failure (22%, n=111). Regarding disease-specific factors contributing to the pathophysiology of AF, cardiac iron overload, defined as at least one between T2*<20 ms and serum ferritin>2500 ng/ml, was present in half of the patients (48.7%, n=76) at any time before AF and in approximately one-third (29%, n=93) at the time of the first event. Thirty-eight patients did not show cardiac iron overload before or at the time of the first AF episode. Most subjects had left atrial dilatation (58.1%), which can result from chronically increased cardiac output due to anemia. In most patients (87%), a rhythm control strategy was chosen at any time. Amiodarone was the most widely used drug. Transcatheter ablation was performed in 29 patients (22%), with a total of 39 procedures, and 20 (77%) patients reported improvement in symptoms after the last ablation. CHA 2DS 2-VASc score at the first AF episode detected a low risk of thromboembolism in 66 (50.8%) patients and a high risk in 19 (14.6%). However, 72 patients, including 40 low-risk subjects, initiated anticoagulation after the first episode. Four patients had a hemorrhagic event (3.1%), but only one had major bleeding during anticoagulant therapy without significant sequelae. Interestingly, management was heterogenous between different centers for both transcatheter ablation use and anticoagulation strategy. The prevalence of stroke in TDT AF patients was 5%, rising to 7.6% when also considering transient ischemic attacks. Compared to the literature, this prevalence is at least 10-fold higher than the general TDT population. Of note, splenectomy, a well-known risk factor for thrombosis, was present in all patients with stroke at the time of the event. In conclusion, AF represents significant morbidity in adult TDT, and its management is heterogeneous. It generally occurs at a younger age than the general population, and iron overload and atrial dilatation play a central role in its genesis. For symptomatic patients, we propose a rhythm control strategy to improve their quality of life, among which ablation could be the best option. Moreover, because stroke represents a major and frequent complication in TDT patients with AF, early detection of AF and prompt initiation of anticoagulant therapy, irrespective of CHA 2DS 2-VASc, which does not capture potential disease-specific risk factors, including splenectomy, should be considered. Further studies to support our approach are needed.
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"Emblematic journeys: Gianni Rodari in the USSR". Cognition, Communication, Discourse, n. 18 (2019). http://dx.doi.org/10.26565/2218-2926-2019-18-02.
Testo completoAbstract (sommario):
The article focuses on the success of the works of the Italian children’s writer Gianni Rodari in the Soviet Union. One of the reasons for Gianni Rodari’s success in his native Italy lies in his previous popularity in the Soviet Union, thanks to early translations of his works by Samuil Marshak and his numerous visits to the USSR beginning in the 1950s. A committed communist, Rodari wanted to get a better understanding of the country that he admired so much. However, his political attitude was not narrow-minded; he investigated the Soviet education system and style of upbringing and communicated with his readers – Soviet children. In Cipollino, the author created a universally acknowledged ideal of a good and honorable hero who fights for freedom, plays in earnest, laughs at difficulties and strives to grow up into a responsible citizen. There are two main factors that contributed to the success of Rodari’s works with Soviet readers: first, their material contains an in-depth interpretation of the concept of utopia. Rodari understood utopia not as an abstraction but as a real responsibility of humanity for its better future. Second, in his creative work, the author pays great attention to folk art, which is a theme running through his rhymes, fairy tales, and stories. Folk tradition was a fundamental element both in Italian children’s literature and the Soviet children’s literature promoted by Marshak and other prominent writers for children in the first half of 20th century. These two vectors are perfectly combined in Cipollino, a favourite character with Soviet children, whose adventures are still being translated and staged in theatres outside Italy. The interaction of these vectors explains why the Italian writer is still widely read and loved, his poems are included in school syllabi, and his words are acquiring a new meaning in the 21st century. The article also reveals the reasons for the lasting popularity of Gianni Rodari’s translated works in intersemiotic cultural space of film and cartoons, ballet etc in Russia, Ukraine and other post-Soviet states.
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Ferraro, Eveljn. "‘La tradizione è come il mare’: Giuseppe Pitrè’s Transnational Approach to Folk and Fairy Tales in the New Italy". Italian Studies, 25 maggio 2022, 1–13. http://dx.doi.org/10.1080/00751634.2022.2070368.
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Geraci, Anna, Vincenza Polizzano e Rosario Schicchi. "Ethnobotanical uses of wild taxa as galactagogues in Sicily (Italy)". Acta Societatis Botanicorum Poloniae 87, n. 2 (29 giugno 2018). http://dx.doi.org/10.5586/asbp.3580.
Testo completoAbstract (sommario):
<p>Breastfeeding furnishes optimal nutrition, immune support, and a multitude of health benefits to mothers and newborns. Since ancient times plants have been employed as galactagogues in the folk medicine of many human cultures. In Sicily, a region with great floristic diversity in the Mediterranean area, where a conspicuous pool of species is traditionally used for food and aromatic, cosmetic, handicraft, agricultural, forestry, and medicinal purposes, some people recognize the galactagogue properties of some spontaneous plants.</p><p>The goal of this study was to identify wild plants with galactagogue properties and vegetable-food remedies traditionally used by women during breastfeeding to increase milk production. It was conducted in the Madonie territory (province of Palermo) by interviewing a sample of 105 people that was divided into three age groups.</p><p>Ethnobotanical investigations revealed a total of 34 species, belonging to 11 families and 25 genera, used as galactagogues. For each taxon, the parts used, the methods of preparation, and the phytochemical profiles according to the literature were reported. The most represented family was Asteraceae, with 12 genera and 17 species, the majority of which contained latex.</p><p>The most frequently used parts of the galactagogue plants were leaves (69%) that were mainly eaten as cooked vegetables, raw in salads, or utilized as an infusion tea. The species cited in this study are mainly wild traditional vegetables with high nutritional profiles that could improve the quality and the quantity of the milk produced. The study found that older people represent a precious source of information to help younger people preserve the cultural identity of the territory.</p>
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Vinogradov, Igor. "TEACHING AND PREACHING IN THE FIRST PRINTED SHORT NOVEL (‘POVEST’) BY NIKOLAI GOGOL (“BISAVRYUK, OR THE EVENING ON THE EVE OF IVAN KUPALA”, 1830)". Проблемы исторической поэтики, dicembre 2022, 54–109. http://dx.doi.org/10.15393/j9.art.2022.10402.
Testo completoAbstract (sommario):
One of the “key” works of Gogol's heritage is analyzed ― the first prose work that appeared in print, the short novel (‘povest’) “Bisavryuk, or The Evening on the Eve of Ivan Kupala” (1830). Gogol’s literary debut in prose is a key work in the sense that it opens the door to understanding the writer’s subsequent work. Based on numerous facts, it is established that since his very first steps in literature, Gogol played the role of a conscious spiritual mentor and preacher. His first prose work (Gogol began as the author of the poems “Italy” and “Gantz Kuchelgarten”) is a sort of literary ekphrasis, which is centered around the theme of spiritual discipline. The short novel (‘povest’) is “theology in images,” and the clergyman, a representative of the common man’s milieu, a rural deacon (church reader, psalm reader), on whose behalf the story is narrated, becomes the author’s alter ego. For the first time, an analytical comparison of two editions of “Evening on the Eve of Ivan Kupala” was undertaken: the original journal version on one side and the subsequent one included in the “Evenings on a Farm near Dikanka” collection (the first edition of the short novel (‘povest’) was called “Bisavryuk, or Evening on the Eve of Ivan Kupala”; in the second, Gogol dropped the beginning of the title, leaving only the second part, “Evening on the Eve of Ivan Kupala”). The comparison shows that the first edition is more frank in expressing the religious views of the author than the second one. In the second edition, Gogol tempered the excessive edification and categorical nature of the original version. It is emphasized that as early as in this short novel (‘povest’), Gogol separates himself from superstitions and “childish prejudices” inherent in popular consciousness and focuses his talent on exposing those phenomena that have survived in the public, folk life from the pagan era. As a faithful ethnographer, a deep connoisseur of folk psychology and folklore, in the first short novel (‘povest’), contrary to the widespread interpretations of his work in radical criticism, the writer already appears not only as an original writer of everyday life, but also an astute thinker and theologian, like his predecessor, St. Tikhon of Zadonsk. From the first “Little Russian” short novel (‘povest’) one can guess many features of the future creator of “Dead Souls”, “Selected Passages from Correspondence with Friends”, and “Reflections on the Divine Liturgy”.
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Mowbray, Miranda. "Neither Male or Female". M/C Journal 3, n. 4 (1 agosto 2000). http://dx.doi.org/10.5204/mcj.1863.
Testo completoAbstract (sommario):
Very large numbers of people habitually spend time interacting in online social spaces based on the software developed by Pavel Curtis for Lambda MOO. Although chatting is part of the functionality of these spaces, it is much richer than the functionality given by basic chat rooms. In particular, members of these spaces explicitly declare a gender within the space (I will call it their 'presenting gender'), which may or may not correspond with their offline gender. As well as the traditional options of "male" and "female", it is possible to choose presenting genders such as "neutral", "royal", or "witch". Around 35% of the members of Media MOO and 22% of Lambda MOO have a presenting gender that is neither "male" nor "female" (Danet). I surveyed active citizens of another such space, Little Italy, by examining 400 characters that had accessed the space during the preceding month. Of these, 72 (18%) had a presenting gender other than "male", "female", and the default, "neutral" (assigned to Little Italians who haven't yet chosen a presenting gender). 11% had default presenting gender. I found that those who had a presenting gender 'other' than "male", "female", or the default were more likely to still be active in Little Italy a year later. This result holds at the 80% significance level -- in other words, there is a less than 1 in 5 probability that the difference observed could have arisen by chance if the distributions were in reality identical. In fact, 'other'-gendered active citizens were 23% more likely than "male" and 32% more likely than "female" active citizens to be still active a year later. This suggests that 'other'-gendered chat may be more a pleasant (or addictive) activity than male- or female-gendered chat. Amazingly, 49% of the 'other'-gendered citizens sampled were still active a year later. This intrigued me, so I sent a message to currently active Little Italians with presenting genders other than male or female, asking them why they had chosen such a presenting gender. I had 28 responses. Quotations from the responses below are by permission, and translated from the Italian. A popular idea amongst gender theorists (e.g. Stone) is that choosing a presenting gender other than "male" and "female" is a strategy for people who don't feel they fit precisely into gender stereotypes. This may include most of us to some degree. As the Kinks sang, "girls will be boys and boys will be girls, it's a mixed-up, muddled-up, shook-up world, except for Lola" -- where Lola has ambiguous presenting gender, and thus is the only non-mixed-up one. This is indeed the reason given by one respondent for choosing a presenting gender other than male or female: "despite being a man, I feel very feminine (since I was small I've always wanted to be a woman)". However, no other respondents gave this as their reason. Another idea from the literature is that of "gender masking" (Jaffe et al. 11-2, and table 1). According to this theory, people, especially women, hide their gender online in order to avoid discrimination and harassment, or gender-related assumptions. Indeed, one respondent described his/her 'masked' character as "a mind without sex or body, an entity without appearance, as insubstantial as a cloud of smoke". On the other hand, the majority of other-gendered Little Italians give some clue that they are either male or female in their character descriptions, and most give some clue when speaking socially within Little Italy. Italian is an inflected language, and has many constructions that reveal whether the speaker is male or female -- it is rare (although not unknown) for a Little Italian to avoid these constructions or to use them ambiguously, as might be expected by someone masking their gender. To consider another idea, Bruckman (also Reid ch. 3 iii) suggests that the online world can be an "identity workshop" (1), where people can emphasise particular aspects of their personality, or try out new personae, or experience what it is like to be someone completely different. Some Little Italians emphasise part of their real identity through their presenting gender, choosing for example to have a gender such as "rebel", "dutch", or "angel". One respondent suggested, "I chose 'angel' because I help everyone who asks me -- and some who don't ask -- let's say I like being a guardian angel ;) and because my name is Michelangelo". Other Little Italians choose 'other' presenting genders precisely because these genders do not have an offline equivalent. Their choice is a form of creativity or escapism. One such respondent asked, "if everything is just like reality, what's the point of logging on?" This creative aspect becomes clear in the more outré genders invented by Little Italians, such as "\V/amp!" for a vampire character, which includes a visual reference to Dracula's high collar, and "...nothing like the sun" (the ellipsis is part of the gender). One surprise was that several citizens became 'other'-gendered by accident! Offline it is difficult to have a sex-change without realising, but online a badly-designed interface can have this effect. 3% of the sample had gender "me", which is a side-effect of a particular mistake in the use of the space. Another surprise was the joke gender. If you ask the system for information about a Little Italy character, one line of the answer is of the form "Sex: <the character's presenting gender>". Around 2% of the sample had presenting genders such as "If only!", "Too much!!", and "Go ahead!!". Several other citizens told me their genders were references to in-jokes amongst their online friends. Some characters had an 'other' gender because the character portrayed was not a human being -- such as a duck with presenting gender "duck", and a character called Harley with presenting gender "H-D". Looking at the 'other' genders in the sample, I was struck by the diversity both of the genders themselves, and of the reasons for which they are chosen. There is no single motive valid for most 'other'-gendered citizens. I was also struck by their lightheartedness. Gender studies texts tend to treat the choice of presenting gender as something highly serious and important. Several writers deal with gender as performance (Butler interviewed by Osborne and Segal, 109-26) or masquerade (Danet) with playful and ironic characteristics (Haraway 149-81). These writers, however, tend to emphasise a serious purpose underlying the performance. Haraway talks of "serious play" (149) and Butler is interested in performing gender as a subversive practice that aims to undermine the dominant forms of gender. Little Italy shows that in online spaces this need not be the case. The Little Italian with presenting gender "duck" does not think of herself as a duck, she is not critiquing female stereotypes, she is not questioning the idea of femaleness, she is not hiding her offline gender to avoid harassment, she is not asserting her inner duckiness; she's just having a bit of fun. Little Italy is more of an identity playground than an identity workshop. The creation of 'other' presenting genders in Little Italy is an example of the unexpectedly creative use of public space by members (in this case the space after Sex: in the character information) that was not originally designed with this use in mind. It is perhaps even more fascinating than other examples of folk art in unexpected places, such as graffiti, crop circles, bumper stickers or carved spoon handles, because of the clarity of its relationship with the artists' (lighthearted) construction of their identities. 'Stickiness' -- the likelihood of visitors to continue visiting a Website over an extended period of time -- is a quality much sought after by e-companies. Little Italy is very 'sticky' for all its citizens, but exceptionally so for other-gendered ones. In my opinion, it is the personal creative investment of the other-gendered citizens in Little Italy that makes them especially likely to remain active citizens. 'Other' presenting genders are possible in Little Italy because Pavel Curtis's software does not limit the options to male and female. This research suggests that designers and administrators of commercial Websites who want stickiness should avoid making assumptions about how their visitors may wish to present and express themselves. Rather, they should try to leave spaces open for their visitors' creativity. Many commercial Websites try to control and limit visitors' interaction, using forms and limited-choice menus. But if I am right about the stickiness of personal creative investment, then this may be a mistake. Creative empowerment of visitors may be better for the bottom line. Acknowledgements Grazie ai cittadini e wiz di Little Italy, sopratutto a quelli citati, per loro aiuto e amichevolezza. References Bruckman, Amy. "Identity Workshop: Emergent Social and Psychological Phenomena in Text-based Virtual Reality." Masters thesis, MIT Media Laboratory. 1992. Danet, Brenda. "Text as Mask: Gender and Identity on the Internet." Conference on "Masquerade and Gendered Identity". Venice, Italy, Feb. 1996. 18 Jul. 2000 <http://atar.mscc.huji.ac.il/~msdanet/mask.php>. Haraway, Donna. "A Cyborg Manifesto: Science, Technology, and Socialist-Feminism in the Late Twentieth Century." Simians, Cyborgs and Women: The Reinvention of Nature. New York: Routledge, 1991. Jaffe, J. Michael, et al. "Gender, Pseudonyms, and CMC: Making Identities and Baring Souls." 45th Annual Conference of the International Communication Association. Albuquerque, USA, 1995. 18 Jul. 2000 <http://members.iworld.net/yesunny/genderps.php>. Osborne, Peter, and Lynne Segal. "Gender as Performance." Interview with Judith Butler. A Critical Sense: Interviews with Intellectuals. Ed. Peter Osborne. London and New York: Routledge, 1996. Elizabeth Reid. "Cultural Formations in Text-based Virtual Realities." Masters thesis, Dept. of English, University of Melbourne. 1994. 11 Aug. 2000 <http://www.aluluei.com>. Stone, Allucquère Rosanne. "Will the Real Body Please Stand Up? Boundary Stories about Virtual Cultures." Cyberspace: First Steps. Ed. Michael Benedikt. Cambridge, MA: MIT P, 1991. 18-118. Citation reference for this article MLA style: Miranda Mowbray. "Neither Male nor Female: Other -- Gendered Chat in Little Italy." M/C: A Journal of Media and Culture 3.4 (2000). [your date of access] <http://www.api-network.com/mc/0008/gendered.php>. Chicago style: Miranda Mowbray, "Neither Male nor Female: Other -- Gendered Chat in Little Italy," M/C: A Journal of Media and Culture 3, no. 4 (2000), <http://www.api-network.com/mc/0008/gendered.php> ([your date of access]). APA style: Miranda Mowbray. (2000) Neither male nor female: other -- gendered chat in Little Italy. M/C: A Journal of Media and Culture 3(4). <http://www.api-network.com/mc/0008/gendered.php> ([your date of access]).
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Giacchetta, I., C. Primieri, R. Cavalieri, A. Domnich e C. de Waure. "The burden of seasonal influenza-associated complications in Italy: a systematic review". European Journal of Public Health 31, Supplement_3 (1 ottobre 2021). http://dx.doi.org/10.1093/eurpub/ckab165.254.
Testo completoAbstract (sommario):
Abstract Background Influenza is the infectious disease with the highest impact on population health in the European Union in terms of disability-adjusted life years. Reliable country-specific influenza-associated burden estimates play a crucial role in informing prevention and control measures to minimize the health and economic burden of the disease. Our purpose was to provide a comprehensive summary of available scientific literature on the burden of seasonal influenza on the Italian population. Methods We performed a systematic literature review of articles published until 31 July 2020. PubMed, Embase and Web of Science were searched. The search strategy included a combination of search terms related to burden, influenza and Italian population. We included studies investigating seasonal influenza-related complications and/or mortality in Italy. A meta-analysis of data was not pre-planned because of the expected heterogeneity in study populations and outcomes. Results A total of 16 studies were included in the qualitative synthesis, out of an original yield of 9,268 articles. Ten (62.5%) and 8 (50%) studies analyzed influenza-related complications and hospitalizations, respectively, while 8 (50%) assessed influenza-related deaths. Only 3 studies (19.7%) concerned pediatric age. The synthesis of results showed that patients with chronic conditions might have an increased risk for complications up to almost 3 times as compared to healthy people. Hospitalization due to influenza can occur from less than 1% to more than 5% according to the study setting (general practice or emergency room). Excess deaths rates were estimated to be over 6-fold higher for the elderly than for the rest of population. Conclusions Although there are still gaps in existing data, there is evidence of the significant burden that influenza places each year especially on high-risk groups. Summaries of the available data may inform decision-making in regard to vaccine strategies and public health policies. Key messages Existing data show evidence of significant burden of influenza on Italian population, especially on high-risk groups. Summaries of country-specific influenza-related burden are crucial in informing vaccine strategies.
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Bertone, Fabio, Emanuele Robiolio, Luca Robiolio, Daniele Liscia e Carmine F. Gervasio. "Three Synchronous Head and Neck Cancers: A Multidisciplinary and Surgical Challenge". Ear, Nose & Throat Journal, 13 aprile 2021, 014556132110079. http://dx.doi.org/10.1177/01455613211007946.
Testo completoAbstract (sommario):
Second primary cancer (SPC) is a term used to describe a new primary cancer occurring in patients who had formerly been diagnosed with tumor. Even though SPCs appear to be related to primary cancers, they are actually entities that have arisen independently and not as a result of recurrence. This report is of the first case in literature of a patient hospitalized for the surgical treatment of 3 synchronous Head and Neck Cancers. A 66-year-old male was admitted to our hospital (Ospedale Degli Infermi—Biella, Italy) complaining about pharyngodynia. Three different lesions were identified through endoscopic examination and narrow band imaging: the first one on left tonsil, the second one on epiglottis, and the third one on right aryepiglottic fold. The case was subject to a multidisciplinary team analysis due to its complexity, then the surgery consisted in (1) CO2 laser left tonsillectomy, associated with (2) CO2 laser excision of the lesion on epiglottis free edge, and (3) CO2 laser excision of right aryepiglottic fold lesion. Synchronous tumors are among the most defiant challenges for surgeons since no international guideline specifies differentiated strategies to be adopted in patients affected by synchronous Head and Neck Cancers, therefore surgical planning must be tailored differently from patient to patient, and many unsolved questions still concern clinical treatments to be adopted.
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Chalampalakis, Emmanouil G., Ioannis Dokas e Eleftherios Spyromitros. "The effect of NPLs management in the PIIGS banking efficiency: an approach using non-parametric partial order-m frontiers". Journal of Economic Studies, 11 agosto 2023. http://dx.doi.org/10.1108/jes-12-2022-0678.
Testo completoAbstract (sommario):
PurposeThis study focuses on the banking systems evaluation in Portugal, Italy, Ireland, Greece and Spain (known as the PIIGS) during the financial and post-financial crisis period from 2009 to 2018.Design/methodology/approachA conditional robust nonparametric frontier analysis (order-m estimators) is used to measure banking efficiency combined with variables highlighting the effects of Non-Performing Loans. Next, a truncated regression is used to examine if institutional, macroeconomic, and financial variables affect bank performance differently. Unlike earlier studies, we use the Corruption Perception Index (CPI) as an institutional variable that affects banking sector efficiency.FindingsThis research shows that the PIIGS crisis affects each bank/country differently due to their various efficiency levels. Most of the study variables — CPI, government debt to GDP ratio, inflation, bank size — significantly affect banking efficiency measures.Originality/valueThe contribution of this article to the relevant banking literature is two-fold. First, it analyses the efficiency of the PIIGS banking system from 2009 to 2018, focusing on NPLs. Second, this is the first empirical study to use probabilistic frontier analysis (order-m estimators) to evaluate PIIGS banking systems.
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Giusy Lavecchia, Rita de Nardis, Daniele Cirillo, Francesco Brozzetti e Paolo Boncio. "The May-June 2012 Ferrara Arc earthquakes (northern Italy): structural control of the spatial evolution of the seismic sequence and of the surface pattern of coseismic fractures". Annals of Geophysics 55, n. 4 (16 ottobre 2012). http://dx.doi.org/10.4401/ag-6173.
Testo completoAbstract (sommario):
The Ferrara 2012 seismic sequence was characterized by two main compressional events, which occurred on May 20 and 29, 2012, with Mw 6.1 and Mw 6.0, respectively (quick Regional Centroid Moment Tensor [RCMT] at http://autorcmt.bo.ingv.it/quicks.html). These events were followed by five events with Mw >5.0 (two on May 20 and three on May 29, 2012) and by hundreds of events of lower magnitudes distributed along a WNW-ESE-elongated area of ca. 500 km2 (ISIDe database at http://iside.rm.ingv.it/ iside/standard/index.jsp.). The ongoing activity of the northward-verging fold-and-thrust structures of the Ferrara-Romagna Arc (Figure 1A) and the eastward-verging Coastal Adriatic Arc (referred to as the Outer Thrust System [OTS] in Lavecchia et al. 2003) has been a debated topic in the Italian literature. […]
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Drysdale, Myriam, Daniel C. Gibbons, Moushmi Singh, Catherine Rolland, Louis Lavoie, Andrew Skingsley e Emily J. Lloyd. "Real-world effectiveness of sotrovimab for the treatment of SARS-CoV-2 infection during Omicron BA.2 subvariant predominance: a systematic literature review". Infection, 30 settembre 2023. http://dx.doi.org/10.1007/s15010-023-02098-5.
Testo completoAbstract (sommario):
Abstract Purpose Emerging SARS-CoV-2 variants have impacted the in vitro activity of sotrovimab, with variable fold changes in neutralization potency for the Omicron BA.2 sublineage and onward. The correlation between reduced in vitro activity and clinical efficacy outcomes is unknown. A systematic literature review (SLR) evaluated the effectiveness of sotrovimab on severe clinical outcomes during Omicron BA.2 predominance. Methods Electronic databases were searched for peer-reviewed journals, preprint articles, and conference abstracts published from January 1–November 3, 2022. Results Five studies were included, which displayed heterogeneity in study design and population. Two UK studies had large samples of patients during BA.2 predominance: one demonstrated clinical effectiveness vs molnupiravir during BA.1 (adjusted hazard ratio [aHR] 0.54, 95% CI 0.33–0.88; p = 0.014) and BA.2 (aHR 0.44, 95% CI 0.27–0.71; p = 0.001); the other reported no difference in the clinical outcomes of sotrovimab-treated patients when directly comparing sequencing-confirmed BA.1 and BA.2 cases (HR 1.17, 95% CI 0.74–1.86). One US study showed a lower risk of 30-day all-cause hospitalization/mortality for sotrovimab compared with no treatment during the BA.2 surge in March (adjusted relative risk [aRR] 0.41, 95% CI 0.27–0.62) and April 2022 (aRR 0.54, 95% CI 0.08–3.54). Two studies from Italy and Qatar reported low progression rates but were either single-arm descriptive or not sufficiently powered to draw conclusions on the effectiveness of sotrovimab. Conclusion This SLR showed that the effectiveness of sotrovimab was maintained against Omicron BA.2 in both ecological and sequencing-confirmed studies, by demonstrating low/comparable clinical outcomes between BA.1 and BA.2 periods or comparing against an active/untreated comparator.
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Musetti, Claudio, Laura Fornara e Vincenzo Cantaluppi. "MO239: Clinical Evaluation of Immunological and Clinical Recurrence of Immune-Mediated Nephropathies after SARS-COV-2 Vaccine". Nephrology Dialysis Transplantation 37, Supplement_3 (maggio 2022). http://dx.doi.org/10.1093/ndt/gfac067.038.
Testo completoAbstract (sommario):
Abstract BACKGROUND AND AIMS The mass vaccination for COVID-19 has raised new concerns for patients with immune-mediated nephropathies: there is a small but growing literature of case-reports linking SARS-CoV-2 vaccines with heightened off-target immune responses leading to de novo or relapsing glomerular diseases [1, 2]. Aim of this study was to evaluate how many and how severe were the relapses of immune-mediated nephropathies after the SARS-CoV-2 vaccine in a single center. METHOD This is a retrospective study held in Italy from the start of the vaccination campaign (late December 2020) to December 31st 2021. We included all patients with an immune-mediated nephropathy (either on or off immunosuppressive therapy—IS), excluding patients with an end-stage renal disease or kidney transplant. In Italy we used mRNA (Comirnaty by Pfizer-BioNTech or Spikevax by Moderna) or adenoviral vector vaccines (Vaxzevria by AstraZeneca or Janssen), without any preference for patients with kidney disease, but those on active IS were given preferentially an mRNA vaccine. There was no active surveillance of lab tests after vaccination and post-vaccine tests were either concomitant to programmed visits or suggested on a patient by patient basis. Recurrence was defined as relapse of nephrotic or nephritic syndrome, doubling of urinary proteins with a max value > 1 g/24h, acute kidney injury with an active urinary sediment, or positivization or 5-fold increase of serological markers of disease activity (i.e.: ANCA in AAV). RESULTS A total of 38 patients (M: F 28:10, age at vaccine 45.9 ± 19.1 years) completed the vaccination protocol: among them, the most common nephropathy was membranous nephropathy (n = 12, 31.6%), followed by IgA nephropathy (n = 7, 18.4%), minimal change disease (n = 6, 15.8%) and ANCA-associated vasculitis (n = 6, 15.8%); 26 patients (68.4%) had at least one other comorbidity. We observed six relapses (4 MN, 1 IgA, 1 AAV), of which only one (MN) developed a mild oedema. The mean time from the first vaccine dose to the relapse was 101 ± 71 days (5–199 days) and only two episodes occurred within 4 weeks from a vaccine dose. We could not find an association between recurrences and maintenance IS at the time of vaccine or any other variable. The overall post-vaccine incidence rate of relapses was 35.8/100 patient-years, as compared with 14.0/100 patient-years historically observed in the same cohort [IRR 2.55, 95% confidence interval (CI) 0.89–5.97]. CONCLUSION Relapses of immune-mediated nephropathies are not common after SARS-CoV-2 vaccine and we did not observe any clinically relevant relapse. However the overall rate of relapse seems to be a little higher than prior vaccination [3], but only 2/6 patients recurred soon after a vaccine dose. As these relapses seem to be self-limiting, a post-vaccine monitoring could be useful in patients at high risk of severe disease.
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Sekikawa, Akira, Katsuyuki Miura, Bradley Willcox, Kamal H. Masaki, Russell P. Tracy, Yoshihiro Miyamoto, Hirotsugu Ueshima e Lewis H. Kuller. "Abstract P364: Recent Trends In Mortality From Coronary Heart Disease Mortality And Its Risk Factors In Selected Developed Countries". Circulation 129, suppl_1 (25 marzo 2014). http://dx.doi.org/10.1161/circ.129.suppl_1.p364.
Testo completoAbstract (sommario):
Objectives: Mortality from coronary heart disease (CHD) in developed countries started to decline in the late 1960’s and early 1970’s and age-adjusted CHD mortality fell about 50%. This decline is attributed to favorable changes in risk factors in the general population, i.e., total cholesterol, blood pressure, smoking, etc., and improved treatment of CHD. We examined recent trends in CHD mortality and its risk factors in selected developed countries. Methods: We selected Australia, Canada, France, Italy, Japan, Spain, Sweden, the UK, and the US. Data on CHD mortality between 1980 and 2005-08 were obtained from the WHO Statistical Information System. To define CHD mortality, codes I20-25 in ICD-10 and corresponding codes in ICDs 8 and 9 were used. Data on risk factors, primarily total cholesterol and systolic blood pressure during the same period were obtained from national surveys as well as literature. Results: in 1980, there was a 2 to 3-fold difference in age-adjusted CHD mortality among these countries both in men and women, with the UK, the US and Canada being high and Japan and France being low. Although between 1980 and 2005-08, age-adjusted CHD mortality continuously declined in all these countries, a 2 to 3-fold difference in the mortality remained with the similar order among these countries. Between 1980 and 2008, age-adjusted mean levels of total cholesterol fell by 21 to 31 mg/dl in men and by 8 to 31 mg/dl in women in these countries except for Japan. Age-adjusted levels of total cholesterol in Japan have continuously increased by 16 mg/dl for both men and women during this period. Meanwhile, between 1980 and 2008 age-adjusted levels of systolic blood pressure fell by 5 to 8 mmHg in men and 6 to 13 mmHg in women in these countries without exception. In 1980, the rate of cigarette smoking in men in Japan was the highest among these countries. Although the rate of smoking in men fell in all these countries, the rates remained the higher in Japan. Conclusions: Age [[Unable to Display Character: –]]adjusted CHD mortality has continuously declined between 1980 and 2005-08 in these developed countries. The decline was accompanied by a constant decrease in population-levels of total cholesterol by 20 to 30 mg/dl except for Japan where levels of total cholesterol have increased by 16 mg/dl. The reasons for persistently low CHD mortality and its downward trend in Japan are unexplained by traditional risk factors. Identifying preventive factors that determine low CHD rates in the Japanese and implementing such factors to the US would eliminate most of CHD epidemics in the US.