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Letteratura scientifica selezionata sul tema "Intracellular pathways"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 15 febbraio 2024

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Articoli di riviste sul tema "Intracellular pathways"

1

Waligora, E. A., C. R. Fisher, N. J. Hanovice, A. Rodou, E. E. Wyckoff, and S. M. Payne. "Role of Intracellular Carbon Metabolism Pathways in Shigella flexneri Virulence." Infection and Immunity 82, no. 7 (April 14, 2014): 2746–55. http://dx.doi.org/10.1128/iai.01575-13.

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ABSTRACTShigella flexneri, which replicates in the cytoplasm of intestinal epithelial cells, can use the Embden-Meyerhof-Parnas, Entner-Doudoroff, or pentose phosphate pathway for glycolytic carbon metabolism. To determine which of these pathways is used by intracellularS. flexneri, mutants were constructed and tested in a plaque assay for the ability to invade, replicate intracellularly, and spread to adjacent epithelial cells. Mutants blocked in the Embden-Meyerhof-Parnas pathway (pfkABandpykAFmutants) invaded the cells but formed very small plaques. Loss of the Entner-Doudoroff pathway gene

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2

Ulevitch, Richard J., David L. Dunn, Mitchell P. Fink, and Christopher E. Taylor. "ENDOTOXIN-RELATED INTRACELLULAR PATHWAYS." Shock 6, no. 1 (July 1996): 1–2. http://dx.doi.org/10.1097/00024382-199607000-00001.

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3

Benitah, Salvador Aznar. "Intracellular signalling pathways and carcinogenesis." Revista de Oncología 3, no. 5 (September 2001): 274–77. http://dx.doi.org/10.1007/bf02719890.

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4

Nahorski, Stefan R. "Pharmacology of intracellular signalling pathways." British Journal of Pharmacology 147, S1 (January 2006): S38—S45. http://dx.doi.org/10.1038/sj.bjp.0706468.

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5

Sanders-Bush, Elaine. "CONTROL OF INTRACELLULAR SIGNALING PATHWAYS." Behavioural Pharmacology 10, SUPPLEMENT 1 (August 1999): S80. http://dx.doi.org/10.1097/00008877-199908001-00203.

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6

LACOMBE, CATHERINE, ISABELLE DUSANTER, STÉPHANIE GOBERT, ODILE MULLER, SYLVIE GISSELBRECHT, and PATRICK MAYEUX. "Intracellular Pathways Activated by Erythropoietina." Annals of the New York Academy of Sciences 718, no. 1 (February 26, 2008): 223–31. http://dx.doi.org/10.1111/j.1749-6632.1994.tb55721.x.

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7

Castle, D., and A. Castle. "Intracellular Transport and Secretion of Salivary Proteins." Critical Reviews in Oral Biology & Medicine 9, no. 1 (January 1998): 4–22. http://dx.doi.org/10.1177/10454411980090010301.

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Intracellular transport and secretion of salivary proteins are major activities of salivary acinar cells. While the major intracellular pathway followed by salivary proteins following their synthesis has been described previously, there is only limited understanding of how this process is regulated at the molecular level. Studies of salivary proteins, especially proline-rich proteins, expressed in an endocrine cell line have begun to provide insight regarding intermolecular interactions during transport and the role played by structural signals during intracellular sorting. Analysis of the sec

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8

Xu, Wen, Bei Wang, Yisong Gao, Yuxuan Cai, Jiali Zhang, Zhiyin Wu, Jiameng Wei, Chong Guo, and Chengfu Yuan. "Alkaloids Exhibit a Meaningful Function as Anticancer Agents by Restraining Cellular Signaling Pathways." Mini-Reviews in Medicinal Chemistry 22, no. 7 (April 2022): 968–83. http://dx.doi.org/10.2174/1389557521666211007114935.

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Abstract: Alkaloids are nitrogen-containing organic compounds widely found in natural products, which play an essential role in clinical treatment. Cellular signaling pathways in tumors are a series of enzymatic reaction pathways that convert extracellular signals into intracellular signals to produce biological effects. The ordered function of cell signaling pathways is essential for tumor cell proliferation, differentiation, and programmed death. This review describes the antitumor progression mediated by various alkaloids after inhibiting classical signaling pathways; related studies are sy

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Pieper, Rembert, C. R. Fisher, Moo-Jin Suh, S. T. Huang, P. Parmar, and S. M. Payne. "Analysis of the Proteome of Intracellular Shigella flexneri Reveals Pathways Important for Intracellular Growth." Infection and Immunity 81, no. 12 (October 7, 2013): 4635–48. http://dx.doi.org/10.1128/iai.00975-13.

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ABSTRACTGlobal proteomic analysis was performed withShigella flexneristrain 2457T in association with three distinct growth environments:S. flexnerigrowing in broth (in vitro),S. flexnerigrowing within epithelial cell cytoplasm (intracellular), andS. flexnerithat were cultured with, but did not invade, Henle cells (extracellular). Compared toin vitroand extracellular bacteria, intracellular bacteria had increased levels of proteins required for invasion and cell-to-cell spread, including Ipa, Mxi, and Ics proteins. Changes in metabolic pathways in response to the intracellular environment also

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Frühbeck, Gema. "Intracellular signalling pathways activated by leptin." Biochemical Journal 393, no. 1 (December 12, 2005): 7–20. http://dx.doi.org/10.1042/bj20051578.

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Leptin is a versatile 16 kDa peptide hormone, with a tertiary structure resembling that of members of the long-chain helical cytokine family. It is mainly produced by adipocytes in proportion to fat size stores, and was originally thought to act only as a satiety factor. However, the ubiquitous distribution of OB-R leptin receptors in almost all tissues underlies the pleiotropism of leptin. OB-Rs belong to the class I cytokine receptor family, which is known to act through JAKs (Janus kinases) and STATs (signal transducers and activators of transcription). The OB-R gene is alternatively splice

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Tesi sul tema "Intracellular pathways"

1

Wilson, Rona Kirstin. "Intracellular pathways in prion peptide trafficking." Thesis, University of Glasgow, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433105.

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`Arnold, Claire. "Intracellular signalling pathways in myeloproliferative neoplasms." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680884.

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Vicario, Chiara. "Magnetogenetic Control of Intracellular Signaling Pathways." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066581/document.

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Le contrôle de l'organisation spatiotemporelle des biomolécules à l'intérieur des cellules vivantes est fondamental pour déchiffrer les mécanismes qui règlent les voies de signalisation cellulaire et leur régulation. Dans ce projet de thèse nous présentons une nouvelle méthode pour induire une perturbation très spécifique et locale des voies de signalisation à l'intérieur des cellules vivantes: la magnétogénétique. Elle est basée sur l'utilisation de nanoparticules magnétiques biofonctionnalisée, pour induire et maintenir des gradients de protéines à l'intérieur des cellules vivantes.Nous avon

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Hutchinson, James Lawrence. "Salmonella interactions with host intracellular trafficking pathways." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611631.

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Nesbeth, Darren Nicholas. "Biochemical studies of intracellular trafficking pathways in eukaryotes." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313830.

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Romero, Alirio Jose Melendez. "Intracellular signalling pathways activated by Fc#gamma#RI." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266462.

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Cullen, Peter J. "A study of the regulation of intracellular calcium." Thesis, University of East Anglia, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277302.

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Behar, Marcelo S. Dohlman Henrik G. "Dynamic regulation and information transfer in intracellular-signaling pathways." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1546.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Physics and Astronomy." Discipline: Physics and Astronomy; Department/School: Physics and Astronomy.

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Pouliot, Philippe. "Implication of intracellular signalling pathways in allergic asthma pathogenesis." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115896.

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The regulation of systemic immune responses is dependent on individual cell responses that will concur to induce a coherent response against a stimulus. In turn, cell response is dependent on the processing of intracellular signals generated at the cell membrane and transmitted through successive protein modifications to the nucleus in order to activate gene transcription. This is referred to as intracellular signalling. Tight control of these mechanisms is required to generate an appropriate cell response to environmental stimulations and globally to establish an appropriate immune response.

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Fitzgerald, Jonathan Basil. "Chondrocyte gene expression and intracellular signaling pathways in cartilage mechanotransduction." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33869.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2005.<br>Includes bibliographical references (p. 152-167).<br>Chondrocytes respond to in vivo mechanical loads by regulating the composition of the cartilage extracellular matrix. This study utilized three loading protocols that span the range of forces and flows induced by in vivo loading. Constant (static) compression of cartilage explants induces a transient hydrostatic pressure buildup and fluid exudation from the compacted matrix until relaxation leads to a new equilibrium compressed state. Dynamic co

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Libri sul tema "Intracellular pathways"

1

Perkins, Jonathan Edwards. A study of EGF-induced intracellular signalling pathways and effects in first trimester trophoblast. Birmingham: University of Birmingham, 2003.

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Conroy, Louise Anne. The development of t-lymphocytes within the murine foetal thymus: The role of intracellular signalling pathways. Birmingham: University of Birmingham, 1992.

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Store-operated Ca2+ entry (SOCE) pathways: Emerging signaling concepts in human (patho)physiology. Wien: Springer, 2012.

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Wilks, Andrew F., and Ailsa G. Harpur. Intracellular Signal Transduction: The JAK-STAT Pathway. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-662-22050-4.

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Wilks, Andrew F. Intracellular signal transduction: The JAK-STAT pathway. New York: Springer, 1996.

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Idestrup, Chris. P2Y-and P2U-purinoceptor activation cause intracellualr CA2+ release in dorsal spinal astrocytes via the phospholipase C[BETA]/IP3 pathway. Ottawa: National Library of Canada, 1996.

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Newell-Price, John, Alia Munir, and Miguel Debono. Normal function of the endocrine system. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0182.

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Endocrinology is the study of hormones (and their glands of origin), their receptors, the intracellular signalling pathways they invoke, and their associated diseases. The clinical specialty of endocrinology focuses specifically on the endocrine organs, that is, the organs whose primary function is hormone secretion, including the hypothalamus, the pituitary, the thyroid, the parathyroid, the adrenal glands, the pancreas, and the reproductive organs.

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Powell, Craig M. PTEN and Autism With Macrocepaly. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199744312.003.0010.

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Phosphatase and Tensin homolog deleted on chromosome 10 (PTEN) is a gene encoding an intracellular signaling molecule. PTEN was originally discovered as the gene responsible for a subset of familial hamartoma (tumor) syndromes associated with increased risk for certain cancers (Nelen et al., 1997) and as a gene often mutated in human cancers and tumor cell lines (Li et al., 1997; Steck et al., 1997). More recently, mutations in PTEN have been linked genetically to the clinical phenotype of autism or developmental delay with macrocephaly (Boccone et al., 2006; Butler et al., 2005; Buxbaum et al

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Fleischmann, Roy. Signalling pathway inhibitors. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0081.

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Oral, small-molecule signalling pathway inhibitors, including ones that inhibit the JAK and SyK pathways, are currently in development for the treatment of rheumatoid arthritis (RA). Tofacitinib is an orally administered small-molecule inhibitor that targets the intracellular Janus kinase 3 and 1 (JAK1/3) molecules to a greater extent than JAK2 while baricitinib (formerly INCB028050) predominantly inhibits JAK1/2. Many of the proinflammatory cytokines implicated in the pathogenesis of RA utilize cell signalling that involves the JAK-STAT pathways and therefore inhibition of JAK-STAT signalling

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Harpur, Ailsa G., and Andrew F. Wilks. Intracellular Signal Transduction: The JAK-STAT Pathway. Springer, 2013.

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Capitoli di libri sul tema "Intracellular pathways"

1

Heineke, Jörg. "Inter- and Intracellular Signaling Pathways." In Congenital Heart Diseases: The Broken Heart, 121–37. Vienna: Springer Vienna, 2016. http://dx.doi.org/10.1007/978-3-7091-1883-2_11.

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Šebestík, Jaroslav, Milan Reiniš, and Jan Ježek. "Dendrimers Regulating Intracellular Signaling Pathways." In Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures, 197–98. Vienna: Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-1206-9_21.

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Thiriet, Marc. "Signaling Pathways." In Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems, 821–909. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4370-4_11.

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Contreras, Monica Sanchez, and Fernando Cardozo-Pelaez. "Chapter 13. Intracellular Signaling Pathways in Parkinson's Disease." In Extracellular and Intracellular Signaling, 247–82. Cambridge: Royal Society of Chemistry, 2011. http://dx.doi.org/10.1039/9781849733434-00247.

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Gómez, Rodolfo, Javier Conde, Morena Scotece, and Oreste Gualillo. "Chapter 3. One Receptor for Multiple Pathways: Focus on Leptin Signaling." In Extracellular and Intracellular Signaling, 44–56. Cambridge: Royal Society of Chemistry, 2011. http://dx.doi.org/10.1039/9781849733434-00044.

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Artemov, Dmitri, and Zaver M. Bhujwalla. "The Tumor Microenvironment in Nanoparticle Delivery and the Role of Imaging to Navigate Roadblocks and Pathways." In Intracellular Delivery III, 301–22. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43525-1_12.

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Ochoa-Alvarez, Jhon Alberto, Candacy George, Harini Krishnan, Xiaoxuan Wu, and Gary S. Goldberg. "Chapter 6. Contact Normalization: Mechanisms and Pathways to Biomarkers and Chemotherapeutic Targets." In Extracellular and Intracellular Signaling, 105–15. Cambridge: Royal Society of Chemistry, 2011. http://dx.doi.org/10.1039/9781849733434-00105.

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Romanelli, Robert J., John T. Williams, and Kim A. Neve. "Dopamine Receptor Signaling: Intracellular Pathways to Behavior." In The Dopamine Receptors, 137–73. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_6.

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Tokarev, Andrei A., Aixa Alfonso, and Nava Segev. "Overview of Intracellular Compartments and Trafficking Pathways." In Trafficking Inside Cells, 3–14. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-93877-6_1.

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Saklatvala, J., A. Clark, and J. Dean. "The Intracellular Signaling Pathways of Inflammatory Stress." In Mechanisms of Organ Dysfunction in Critical Illness, 137–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56107-8_9.

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Atti di convegni sul tema "Intracellular pathways"

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Dörner, Thomas. "09 Novel intracellular pathways." In 9th Annual Meeting of the Lupus Academy. Lupus Foundation of America, 2020. http://dx.doi.org/10.1136/lupus-2020-la.9.

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"04 Targeting novel intracellular pathways." In 8th ANNUAL MEETING OF THE LUPUS ACADEMY, Warsaw, Poland, September 6–8, 2019. Lupus Foundation of America, 2019. http://dx.doi.org/10.1136/lupus-2019-la.16.

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Bando, Kazuki, Katsumasa Fujita, Nicholas Smith, Jun Ando, and Satoshi Kawata. "3D Dynamic SERS Imaging of Intracellular Transport Pathways." In JSAP-OSA Joint Symposia. Washington, D.C.: OSA, 2013. http://dx.doi.org/10.1364/jsap.2013.19p_d4_7.

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Archała, Aneta, та Anita Płazińska. "β2-adrenergic receptor polymorphism in intracellular signalling pathways". У 1st International Electronic Conference on Biomedicine. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/ecb2021-10265.

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Jinghua Gu, Chen Wang, Le-Ming Shih, Tian-Li Wang, Yue Wang, R. Clarke, and Jianhua Xuan. "GIST: A Gibbs sampler to identify intracellular signal transduction pathways." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6090677.

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Bartholome, Kilian, Jens Timmer, and Markus Kollmann. "Design principles of signal transduction pathways to compensate intracellular perturbations." In 2006 IEEE Conference on Computer Aided Control System Design, 2006 IEEE International Conference on Control Applications, 2006 IEEE International Symposium on Intelligent Control. IEEE, 2006. http://dx.doi.org/10.1109/cacsd-cca-isic.2006.4776902.

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Bartholome, Kilian, Jens Timmer, and Markus Kollmann. "Design Principles of Signal Transduction Pathways to compensate Intracellular Perturbations." In 2006 IEEE International Conference on Control Applications. IEEE, 2006. http://dx.doi.org/10.1109/cca.2006.286134.

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Lu, X. Lucas, Bo Huo, Andrew D. Baik, and X. Edward Guo. "Intercellular Calcium Wave Propagation in Linear and Circuit-Like Bone Cell Networks." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19365.

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Intracellular calcium ([Ca2+]i) transients in response to mechanical stimulation can be propagated to neighboring cells in bone cell networks, which provides an essential mechanism for cell-cell communication in bone. Transfer of intracellular second messengers (e.g., IP3 and Ca2+) through gap junction pores and the diffusion of extracellular ATP to activate membrane receptors have long been conjectured as the two major pathways for intercellular Ca2+ wave propagation [1]. In this study, by comparing the calcium wave in open-end linear and looped circuit-like cell chains, the roles of gap junc

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Wu, Yicong, Wei Zheng, and Jianan Y. Qu. "Monitoring cellular metabolic pathways by wavelength- and time-resolved intracellular autofluorescence." In European Conference on Biomedical Optics. Washington, D.C.: OSA, 2007. http://dx.doi.org/10.1364/ecbo.2007.6628_5.

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Wu, Yicong, Wei Zheng, and Jianan Y. Qu. "Monitoring cellular metabolic pathways by wavelength- and time-resolved intracellular autofluorescence." In European Conference on Biomedical Optics, edited by Dietrich Schweitzer and Maryann Fitzmaurice. SPIE, 2007. http://dx.doi.org/10.1117/12.727610.

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Rapporti di organizzazioni sul tema "Intracellular pathways"

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Naim, Michael, Andrew Spielman, Shlomo Nir, and Ann Noble. Bitter Taste Transduction: Cellular Pathways, Inhibition and Implications for Human Acceptance of Agricultural Food Products. United States Department of Agriculture, February 2000. http://dx.doi.org/10.32747/2000.7695839.bard.

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Historically, the aversive response of humans and other mammals to bitter-taste substances has been useful for survival, since many toxic constituents taste bitter. Today, the range of foods available is more diverse. Many bitter foods are not only safe for consumption but contain bitter constituents that provide nutritional benefits. Despite this, these foods are often eliminated from our current diets because of their unacceptable bitterness. Extensive technology has been developed to remove or mask bitterness in foods, but a lack of understanding of the mechanisms of bitterness perception a

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Bazer, Fuller W., Arieh Gertler, and Elisha Gootwine. Role of Placental Lactogen in Sheep. United States Department of Agriculture, January 2001. http://dx.doi.org/10.32747/2001.7574339.bard.

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Central problems in sheep and dairy cattle production are reproductive failure due to embryonic/fetal mortality and low birth weights, especially in prolific breeds, and reduced milk yields which adversely affect neonatal survival and economy of production. The sheep placenta expresses lactogenic (ovine placental lactogen, oPL) and somatogenic (ovine placental growth hormone, oGH) hormones. Our research has focused on the biological roles of oPL and oGH in function of the uterine endometrium during gestation and the mammary gland during pregnancy and lactation. Major conclusions were that: ( 1

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3

Or, Etti, David Galbraith, and Anne Fennell. Exploring mechanisms involved in grape bud dormancy: Large-scale analysis of expression reprogramming following controlled dormancy induction and dormancy release. United States Department of Agriculture, December 2002. http://dx.doi.org/10.32747/2002.7587232.bard.

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The timing of dormancy induction and release is very important to the economic production of table grape. Advances in manipulation of dormancy induction and dormancy release are dependent on the establishment of a comprehensive understanding of biological mechanisms involved in bud dormancy. To gain insight into these mechanisms we initiated the research that had two main objectives: A. Analyzing the expression profiles of large subsets of genes, following controlled dormancy induction and dormancy release, and assessing the role of known metabolic pathways, known regulatory genes and novel se

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Wang, X. F., and M. Schuldiner. Systems biology approaches to dissect virus-host interactions to develop crops with broad-spectrum virus resistance. Israel: United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134163.bard.

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More than 60% of plant viruses are positive-strand RNA viruses that cause billion-dollar losses annually and pose a major threat to stable agricultural production, including cucumber mosaic virus (CMV) that infects numerous vegetables and ornamental trees. A highly conserved feature among these viruses is that they form viral replication complexes (VRCs) to multiply their genomes by hijacking host proteins and remodeling host intracellular membranes. As a conserved and indispensable process, VRC assembly also represents an excellent target for the development of antiviral strategies that can b

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