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Letteratura scientifica selezionata sul tema "Integrative conjugative element (ICE)"

Autore: Grafiati

Pubblicato: 8 giugno 2024

Ultima modifica: 31 luglio 2025

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Articoli di riviste sul tema "Integrative conjugative element (ICE)"

Iannelli, Francesco, Francesco Santoro, Marco R. Oggioni, and Gianni Pozzi. "Nucleotide Sequence Analysis of Integrative Conjugative Element Tn5253of Streptococcus pneumoniae." Antimicrobial Agents and Chemotherapy 58, no. 2 (2013): 1235–39. http://dx.doi.org/10.1128/aac.01764-13.

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ABSTRACTConjugative transposon Tn5253, an integrative conjugative element (ICE) ofStreptococcus pneumoniaecarrying thecatandtet(M) genes, was shown to be 64,528 bp in size and to contain 79 open reading frames, of which only 38 could be annotated. Two distinct genetic elements were found integrated into Tn5253: Tn5251(18,033 bp), of the Tn916-Tn1545family of ICEs, and Ωcat(pC194) (7,627 bp), which could not conjugate but was capable of intracellular mobility by excision, circularization, and integration by homologous recombination. The highest conjugation frequency of Tn5253was observed whenSt

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Libante, Virginie, Nazim Sarica, Abbas Mohamad Ali, et al. "Mobilization of IMEs Integrated in the oriT of ICEs Involves Their Own Relaxase Belonging to the Rep-Trans Family of Proteins." Genes 11, no. 9 (2020): 1004. http://dx.doi.org/10.3390/genes11091004.

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Integrative mobilizable elements (IMEs) are widespread but very poorly studied integrated elements that can excise and hijack the transfer apparatus of co-resident conjugative elements to promote their own spreading. Sixty-four putative IMEs, harboring closely related mobilization and recombination modules, were found in 14 Streptococcus species and in Staphylococcus aureus. Fifty-three are integrated into the origin of transfer (oriT) of a host integrative conjugative element (ICE), encoding a MobT relaxase and belonging to three distant families: ICESt3, Tn916, and ICE6013. The others are in

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Giovanetti, Eleonora, Andrea Brenciani, Erika Tiberi, Alessandro Bacciaglia, and Pietro Emanuele Varaldo. "ICESp2905, theerm(TR)-tet(O) Element of Streptococcus pyogenes, Is Formed by Two Independent Integrative and Conjugative Elements." Antimicrobial Agents and Chemotherapy 56, no. 1 (2011): 591–94. http://dx.doi.org/10.1128/aac.05352-11.

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ABSTRACTIn ICESp2905, a widespreaderm(TR)- andtet(O)-carrying genetic element ofStreptococcus pyogenes, the two resistance determinants are contained in separate fragments inserted into a scaffold of clostridial origin. ICESp2905(∼65.6 kb) was transferable not only in its regular form but also in a defective form lacking theerm(TR) fragment (ICESp2906, ∼53.0 kb). Theerm(TR) fragment was also an independent integrative and conjugative element (ICE) (ICESp2907, ∼12.6 kb). ICESp2905thus results from one ICE (ICESp2907) being integrated into another (ICESp2906).

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Del Grosso, Maria, Romina Camilli, Ermanno Rizzi, Alessandro Pietrelli, Gianluca De Bellis, and Annalisa Pantosti. "ICESpy009, a Conjugative Genetic Element Carryingmef(E) in Streptococcus pyogenes." Antimicrobial Agents and Chemotherapy 60, no. 7 (2016): 3906–12. http://dx.doi.org/10.1128/aac.03082-15.

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ABSTRACTEfflux-mediated macrolide resistance due tomef(E) andmel, carried by the mega element, is common inStreptococcus pneumoniae, for which it was originally characterized, but it is rare inStreptococcus pyogenes. InS. pyogenes, mega was previously found to be enclosed in Tn2009, a composite genetic element of the Tn916family containingtet(M) and conferring erythromycin and tetracycline resistance. In this study,S. pyogenesisolates containingmef(E), apparently not associated with other resistance determinants, were examined to characterize the genetic context of mega. By whole-genome sequen

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Michael, G. B., K. Kadlec, M. T. Sweeney, et al. "ICEPmu1, an integrative conjugative element (ICE) of Pasteurella multocida: structure and transfer." Journal of Antimicrobial Chemotherapy 67, no. 1 (2011): 91–100. http://dx.doi.org/10.1093/jac/dkr411.

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Auchtung, Jennifer M., Naira Aleksanyan, Artemisa Bulku, and Melanie B. Berkmen. "Biology of ICE Bs1 , an integrative and conjugative element in Bacillus subtilis." Plasmid 86 (July 2016): 14–25. http://dx.doi.org/10.1016/j.plasmid.2016.07.001.

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Calcutt, Michael J., Michelle S. Lewis, and Kim S. Wise. "Molecular Genetic Analysis of ICEF, an Integrative Conjugal Element That Is Present as a Repetitive Sequence in the Chromosome of Mycoplasma fermentans PG18." Journal of Bacteriology 184, no. 24 (2002): 6929–41. http://dx.doi.org/10.1128/jb.184.24.6929-6941.2002.

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ABSTRACT Mycoplasma genomes contain compact gene sets that approach the minimal complement necessary for life and reflect multiple evolutionary instances of genomic reduction. Lateral gene transfer may play a critical role in shaping the mobile gene pool in these organisms, yet complex mobile elements have not been reported within this genus. We describe here a large (∼23-kb) genetic element with unique features that is present in four copies in the Mycoplasma fermentans PG18 chromosome, accounting for approximately 8% of the genome. These novel elements, designated ICEF (integrative conjugal

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Selyanskaya, N. A., S. V. Titova, E. A. Menshikova, S. O. Vodopyanov, and V. D. Kruglikov. "Influence of Cultivation Conditions on the Transmission of Antibiotic Resistance Genes in Vibrio cholera." Antibiot Khimioter = Antibiotics and Chemotherapy 69, no. 9-10 (2025): 4–10. https://doi.org/10.37489/0235-2990-2024-69-9-10-4-10.

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The growth of antibiotic resistance necessitates studying the processes of acquisition and loss of genetic elements responsible for resistance. The aim of the study was to investigate the effect of temperature, biofilm formation, and antibiotics on the efficiency of integrative conjugative element (ICE) transfer in Vibrio cholerae O1 El Tor strains. Material and methods. Conjugative transfer of the ICE element from V. cholerae O1 El Tor strains to Escherichia сoli QD 5003 Rifr and V. cholera O1 El Tor 5879 Nalr cells was carried out in plankton and in biofilms on plastic and chitin at 25–37°C.

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Levicán, Gloria J., Assaf Katz, Jorge H. Valdés, Raquel Quatrini, David S. Holmes, and O. Orellana. "A 300 kpb Genome Segment, Including a Complete Set of tRNA Genes, is Dispensable for Acidithiobacillus Ferrooxidans." Advanced Materials Research 71-73 (May 2009): 187–90. http://dx.doi.org/10.4028/www.scientific.net/amr.71-73.187.

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The genome sequences from two strains of the acidophilic, autotrophic, chemolithotrophic proteobacterium A. ferrooxidans are available from genome databases. Bioinformatic sequence comparison revealed the existence in one strain of a putative integrative conjugative element (ICE), containing an entire set of clustered tRNA genes. ICE is missing in the other strain, suggesting that this element as well as the tRNA genes cluster is dispensable for the bacterium. Bioinformatic predictions suggest that the tRNA genes cluster might mainly contribute to the translation of ICE encoded genes.

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McKeithen-Mead, Saria A., and Alan D. Grossman. "Timing of integration into the chromosome is critical for the fitness of an integrative and conjugative element and its bacterial host." PLOS Genetics 19, no. 2 (2023): e1010524. http://dx.doi.org/10.1371/journal.pgen.1010524.

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Abstract (sommario):

Integrative and conjugative elements (ICEs) are major contributors to genome plasticity in bacteria. ICEs reside integrated in the chromosome of a host bacterium and are passively propagated during chromosome replication and cell division. When activated, ICEs excise from the chromosome and may be transferred through the ICE-encoded conjugation machinery into a recipient cell. Integration into the chromosome of the new host generates a stable transconjugant. Although integration into the chromosome of a new host is critical for the stable acquisition of ICEs, few studies have directly investig

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Più fonti

Tesi sul tema "Integrative conjugative element (ICE)"

Coluzzi, Charles. "L'exploration des génomes par l'outil ICEFinder révèle la forte prévalence et l'extrême diversité des ICE et des IME de streptocoques." Thesis, Université de Lorraine, 2017. http://www.theses.fr/2017LORR0352/document.

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Abstract (sommario):

Les éléments génétiques mobiles contribuent grandement à la diversité et à l’évolution des génomes bactériens par le biais du transfert horizontal. Parmi eux, les éléments intégratifs conjugatifs (ICE) codent leur propre excision, leur transfert par conjugaison et leur intégration. En revanche, les éléments intégratifs et mobilisables (IME) ne sont autonomes que pour leur excision et intégration et ne codent seulement que certaines des protéines/fonctions (oriT) dont ils ont besoin pour leur transfert conjugatif. Par conséquent, les IME ont besoin d’un élément conjugatif « helper » pour se tra

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Lao, Julie. "Conception et mise en oeuvre d’une approche bioinformatique dédiée à l’identification des ICE, IME et éléments composites dans les génomes de Firmicutes." Electronic Thesis or Diss., Université de Lorraine, 2021. http://www.theses.fr/2021LORR0063.

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Abstract (sommario):

Les ICE (Éléments intégratifs conjugatifs) et les IME (Éléments intégratifs mobilisables) sont des éléments mobiles bactériens qui jouent un rôle clé dans les transferts horizontaux. Ils ont la capacité de s'intégrer et de se transférer par conjugaison d'une bactérie à une autre. Ces éléments sont très répandus dans les génomes bactériens mais sont encore mal connus. Leur identification automatique est un défi et ils ne sont en général pas annotés dans les génomes. Jusqu'à présent, seules deux approches bioinformatiques permettent la détection des ICE et la détection des IME, mais leur fiabili

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Laroussi, Haifa. "Étude des mécanismes moléculaires d'initiation du transfert conjugatif d'ICESt3, médiée par une relaxase MOBT chez la bactérie Gram+ Streptococcus thermophilus." Electronic Thesis or Diss., Université de Lorraine, 2022. http://www.theses.fr/2022LORR0176.

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Les génomes bactériens évoluent principalement grâce au transfert horizontal de gènes. La conjugaison bactérienne en est un des mécanismes majeurs. Elle est notamment médiée par les éléments intégratifs et conjugatifs (ICE). En plus de leur transfert, les ICE codent d'autres fonctions conférant à leur hôte un avantage adaptatif, comme par exemple des résistances aux antibiotiques dont la diffusion est un enjeu majeur en santé publique. Il est donc nécessaire de comprendre comment les ICE se transfèrent si l'on veut limiter leur dissémination. Le transfert d'un ICE d'une cellule donatrice vers

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Nouvel, Laurent-Xavier. "Etude de la diversité génétique de Mycoplasma agalactiae : plasticité des génomes, mobilome et dynamique de surface." Thesis, Toulouse, INPT, 2009. http://www.theses.fr/2009INPT013A/document.

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Mycoplasma agalactiae est responsable de l'agalactie contagieuse, maladie des petits ruminants difficilement contrôlée et figurant sur la liste de l’OIE. Afin d’évaluer la diversité génétique de ce pathogène, 101 isolats ont été comparés par trois techniques (VNTR, RFLP, répertoire vpma). Les résultats révèlent une grande homogénéité génétique dont la souche type PG2 est représentative. Quelques isolats font exception telle la souche 5632 que nous avons séquencée et analysée ici. La comparaison des génomes et des protéomes entre 5632 et PG2 indiquent que la plasticité de ces génomes est liée à

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SANTORO, FRANCESCO. "Functional characterization of the pneumococcal Integrative Conjugative Element Tn5253." Doctoral thesis, Università di Siena, 2017. http://hdl.handle.net/11365/1005925.

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Integrative conjugative elements (ICEs) are responsible for pneumococcal genome evolution and more particularly for virulence and drug resistance acquisition. During conjugation, ICEs transfer from a donor cell containing the genetic element to a recipient cell lacking it. ICEs insert into the bacterial genome, excise from it and form a covalently closed circular intermediate which can integrate in a different genomic site and/or can integrate in a new genome upon conjugative transfer. Tn5253 is a composite ICE of Streptococcus pneumoniae conferring resistance to tetracycline and chloramphe

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Harden, Mark Michael Jr. "Interactions between an integrative and conjugative element and its bacterial host." Thesis, Massachusetts Institute of Technology, 2021. https://hdl.handle.net/1721.1/130662.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, February, 2021 Cataloged from the official PDF of thesis. Includes bibliographical references. Conjugative elements are mobile genetic elements that can transfer from a donor bacterium to a recipient via an element-encoded type IV secretion system. Integrative and conjugative elements (ICEs) are an abundant class of conjugative element. ICEs are typically integrated into the bacterial host chromosome, but under certain conditions, or stochastically, they can excise from the chromosome and transfer to a recip

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Avello, Monika M. M. (Monika Maria Masumi). "Characterization of an exclusion mechanism in an integrative and conjugative element in Bacillus subtilis." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/119980.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2018. Cataloged from PDF version of thesis. Includes bibliographical references. Horizontal gene transfer is the acquisition of new genetic material that can confer novel phenotypes to bacteria and contribute to their evolution. Conjugation is an important mechanism of horizontal gene transfer that involves the direct transfer of DNA between two cells and is mediated by mobile genetic elements encoding type IV secretion systems. Conjugative elements prevent redundant transfer by a mechanism known as exclusio

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Eidam, Christopher [Verfasser]. "Molecular analysis of multiresistant Mannheimia haemolytica isolates with particular reference to novel macrolide resistance genes and variants of the integrative and conjugative element ICEPmu1 / Christopher Eidam." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2014. http://d-nb.info/106486256X/34.

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fox, Valeria. "Mobile genetic elements carrying stress response systems, antibiotic resistance determinants, and catabolic pathways." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1159250.

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In the present thesis, I studied the activation of an SOS-like response in Streptococcus pneumoniae encoded by the Streptococcus pyogenes prophage φ1207.3. This system leads to the temporary activation of an hypermutable phenotype, which resulted in increased survival and increased mutation rate upon exposure to mitomycin C or UV-C light. Then, a different type of stress response, the Envelope Stress Response (ESR), was exploited as a strategy for sensitization of Escherichia coli to several antibiotics, by disbalancing five pathways, namely σE, Cpx, Rcs, Bae, and Psp. Disbalancing the Psp pat

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Carraro, Nicolas. "Analyse comparative de la dynamique de deux éléments intégratifs conjugatifs de streptococcus thermophilus." Thesis, Nancy 1, 2011. http://www.theses.fr/2011NAN10080/document.

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Abstract (sommario):

Les éléments intégratifs conjugatifs (ICE) sont des îlots génomiques qui codent leur excision du chromosome, leur transfert par conjugaison et leur intégration. Ils présentent une organisation modulaire, chaque module incluant tous les gènes nécessaires pour conférer une fonction biologique. Ce travail a porté sur l'étude de la régulation ainsi que les modalités de transfert et de maintien d'ICESt1 et ICESt3, deux ICE de Streptococcus thermophilus présentant une région core étroitement apparentée et une région variable non apparentée. Les résultats obtenus ont montré que, bien qu'ICESt3 s'exci

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Capitoli di libri sul tema "Integrative conjugative element (ICE)"

Armshaw, Patricia, and J. Tony Pembroke. "UV Stress-Responsive Genes Associated with Enterobacterial Integrative Conjugative Elements of the ICE SXT/R391 Group." In Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria. John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119004813.ch48.

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Berkmen, Melanie B., Stephanie J. Laurer, Bridget K. Giarusso, and Rodrigo Romero. "The Integrative and Conjugative Element ICEBs1 of Bacillus subtilis." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-12.

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