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1

Rendell-Baker, L., e Julius H. Jacobson. "Hyperbaric Oxygenation". International Anesthesiology Clinics 37, n. 1 (1999): 137–68. http://dx.doi.org/10.1097/00004311-199903710-00008.

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Jones, William E. "Hyperbaric oxygenation therapy". Journal of Equine Veterinary Science 20, n. 4 (aprile 2000): 241–83. http://dx.doi.org/10.1016/s0737-0806(00)80338-x.

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3

Levina, O. A., A. K. Evseev, M. Sh Khubutiya, A. V. Babkina e A. K. Shabanov. "Hyperbaric oxygenation in transplantology". Transplantologiya. The Russian Journal of Transplantation 12, n. 1 (18 marzo 2020): 28–41. http://dx.doi.org/10.23873/2074-0506-2020-12-1-28-41.

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Abstract (sommario):
The ability to eliminate any form of oxygen debt by transporting oxygen to organs and tissues, by dissolving it in body fluids, brings hyperbaric oxygenation to a new level of application in transplantology. The review discusses the pathophysiological aspects of hyperbaric oxygenation during ischemia and reinfusion, especially when used in transplantology, and also investigations on the use of hyperbaric oxygenation in model experiments and in clinical practice. Analysis of the efficacy of hyperbaric oxygenation therapy at various stages of the transplantation process (preconditioning, donation, organ storage, in the early and late post-transplant periods) allows us to conclude that this method should be more widely involved in transplantation practice.Authors declare no conflict of interest.
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Rozhko, J. I., e N. V. Karpovich. "APPLICATION OF HYPERBARIC OXYGENATION IN GLAUCOMA OPTIC NEUROPATHY THERAPY". Health and Ecology Issues, n. 1 (28 marzo 2009): 42–45. http://dx.doi.org/10.51523/2708-6011.2009-6-1-7.

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We assed the Hyperbaric Oxygenation neuroprotection effect of treatment in patient with primary open-angle glaucoma. Аge range (45-75 years) patients with primary open-angle glaucoma with normal intraocular pressure were treated with Hyperbaric Oxygenation as monotherapy. Complete ophthalmologic examination, including visual acuity, tonometry, electronic tonography, kinetic perimetry, campimetry, analysis of blood flow was performed. As a results of dynamic functional inspection of patient with primary open-angle glaucoma with normal intraocular pressure marks improvement of basic parameters reflecting a ganglion cells condition that testifies to good efficiency of a Hyperbaric Oxygenation in neuroprotection therapy glaucoma neuropathy. Hyperbaric Oxygenation can be recommended for out - patient treatment.
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Smith, Robert M. "ANESTHESIA DURING HYPERBARIC OXYGENATION". Annals of the New York Academy of Sciences 117, n. 2 (14 marzo 2007): 768–73. http://dx.doi.org/10.1111/j.1749-6632.1964.tb56326.x.

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Dohgomori, H., K. Arikawa e H. Kubo. "The Accuracy and Reliability of an Infusion Pump (STC-3121; Terumo Inst., Japan) during Hyperbaric Oxygenation". Anaesthesia and Intensive Care 28, n. 1 (febbraio 2000): 68–71. http://dx.doi.org/10.1177/0310057x0002800113.

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We evaluated the accuracy of delivery of one type of infusion pump at three nominal flow rates under two environmental pressures (measured in atmospheres absolute, ATA), one of which is used for hyperbaric oxygenation. Overall, we observed significant differences between the two different pressures (1 ATA and 2 ATA). Changes in the rate of delivery of between about −4% and +2% were observed over the time course of hyperbaric oxygenation, and the inter-group difference was significant in the phases in which pressure was changing. The effect produced by 2 ATA was statistically significant but small, and its influence is likely to be negligible during practical hyperbaric oxygenation therapy. Thus, it would seem that this type of pump would deliver reliably at the nominal rate during hyperbaric oxygenation at these levels.
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Kondratyeva, Tatyana Nikolaevna, e Natalya Alekseevna Kutalova. "Hyperbaric oxygenation in the implementation of rehabilitation measures after COVID-19 pneumonia". Medsestra (Nurse), n. 5 (1 maggio 2021): 7–11. http://dx.doi.org/10.33920/med-05-2105-01.

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The aim of the study was to research the hyperbaric oxygenation effect on the condition of patients in the course of complex treatment aimed at rehabilitation after suffering from COVID-19 pneumonia. Results: the impact of hyperbaric oxygenation on the body of patients who have suffered from the novel coronavirus infection provides a positive dynamics and improves their quality of life. Conclusion: in the process of rehabilitating patients who have undergone the new coronavirus infection, it is necessary to use various physiotherapeutic measures, including hyperbaric oxygenation.
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Мальцева e L. Maltseva. "Hyperoxia effect on humoral and cell components of immunobiological resistance of healthy rats in experiment". Journal of New Medical Technologies. eJournal 8, n. 1 (5 novembre 2014): 1–6. http://dx.doi.org/10.12737/4112.

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The paper contains information about hyperbaric oxygenation impact on humoral and cell components of immune-biological resistance of healthy rats. The following factors are analyzed: potency of oxygen-dependent enzyme systems (myeloperoxidase, oxidase), oxygen-independent systems (leukocyte lysozyme, cationic proteins), killing reactions of peripheral blood neutrophils, their phagocytic and oxidase reserve, complement activity and content of circulating immune complexes in the blood serum of healthy animals, which have been exposed to 60-minute sessions of hyperbaric oxygenation, over time from the 1st to the 30th day post hyperoxia period during experiment. A single session of hyperbaric oxygenation is carried out within 60 minutes (3 absolute atmospheres mode). Mechanisms of adaptation and pathological reactions formation by immune-biological surveillance system of healthy body in early and late post hyperoxia periods during experiment are considered. The paper shows that adaptive responses, which are designed to protect the body against aggressive action of oxygen under the influence of hyperbaric oxygenation, are formed in the bodies of healthy animals. The reactions of oxygen-dependent of phagocytes systems in conditions of hyperoxia manifested in the early stages of the research, persisting to the end of the observation and the reactions of oxygen independent - only at early stages. The humoral responses of healthy organism under hyperbaric oxygen are characterized by the change in complement activity and concentration of circulating immune complexes in blood serum. The received experimental data may be used as a theoretical explanation of indications for use of hyperbaric oxygen therapy and different hyperbaric oxygenation regimes.
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9

Krasnov, A. F., N. F. Davydkin, A. P. Chernov e L. A. Orlova. "Application of hyperbaric oxygenation in patients with consequences of poliomyelitis". Kazan medical journal 67, n. 3 (15 maggio 1986): 209–10. http://dx.doi.org/10.17816/kazmj70081.

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We included hyperbaric oxygenation in the complex treatment of 82 patients with consequences of poliomyelitis. We also studied archival materials on 82 patients with similar manifestations of poliomyelitis and identical treatment, but without the use of hyperbaric oxygenation. They formed a control group.
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Tsankova, Krasimira, e Mila Dimitrova. "HISTORICAL DEVELOPMENT OF THE HYPERBARIC OXYGENATION". Journal of IMAB - Annual Proceeding (Scientific Papers) 27, n. 2 (7 giugno 2021): 3772–77. http://dx.doi.org/10.5272/jimab.2021272.3772.

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Background: Hyperbaric oxygenation (HBO) is a treatment in which a patient breathes near 100% oxygen within a chamber at a pressure greater than one atmosphere absolute (ATA). The development of hyperbaric medicine is continuous and associated with the history of underwater activities, the development of physical laws and physiological mechanisms of breathing. Purpose: The aim of this article is to present the development of hyperbaric oxygenation internationally and nationally. Materials and Methods: We have conducted a literature review of the published works on hyperbaric oxygen therapy (HBOT) during the last 100 years. Our survey includes scientific reports and books in English and Bulgarian. Results: Three main periods of the historical development of HBOT can be defined. In the past, HBO did not have much scientific support but is extensively used in the field of medicine. We observed an increase in scientific interest in HBO during the last two decades both in our country and worldwide. The majority of the reviewed articles contained information about different aspects of HBO as clinical uses, effects, risks. HBOT has been used as a primary and adjuvant treatment for a variety of diseases for nearly 50 years in Bulgaria. The main areas of application and researches of hyperbaric oxygen therapy include diving diseases, intoxications, traumatic injuries, soft tissue infections, diabetic foot, hearing loss, some neurological disorders, etc. Conclusion: Over the past decades, hyperbaric oxygen therapy has grown rapidly worldwide in accordance with evidence-based medicine methods, and future developments to expand the knowledge are perspective.
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Broussard, C. "Hyperbaric oxygenation and wound healing". Journal of WOCN 30, n. 4 (luglio 2003): 210–16. http://dx.doi.org/10.1067/mjw.2003.135.

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Neubauer, RA. "Hyperbaric oxygenation for cerebral palsy". Lancet 357, n. 9273 (giugno 2001): 2052. http://dx.doi.org/10.1016/s0140-6736(00)05136-9.

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James, Philip B. "Hyperbaric oxygenation for cerebral palsy". Lancet 357, n. 9273 (giugno 2001): 2052–53. http://dx.doi.org/10.1016/s0140-6736(00)05137-0.

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14

Collet, JP, M. Lassonde, SD Tremblay, J. Lacroix e A. Majnemer. "Hyperbaric oxygenation for cerebral palsy". Lancet 357, n. 9273 (giugno 2001): 2053. http://dx.doi.org/10.1016/s0140-6736(00)05138-2.

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15

Heuser, Gunnar, e J. Michael Uszler. "Hyperbaric oxygenation for cerebral palsy". Lancet 357, n. 9273 (giugno 2001): 2053–54. http://dx.doi.org/10.1016/s0140-6736(00)05139-4.

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16

James, Philip B. "Hyperbaric oxygenation in fluid microembolism". Neurological Research 29, n. 2 (marzo 2007): 156–61. http://dx.doi.org/10.1179/016164107x181789.

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17

Illingworth, Sir Charles. "ARTERIAL INSUFFICIENCY AND HYPERBARIC OXYGENATION". Annals of the New York Academy of Sciences 117, n. 2 (14 marzo 2007): 671–72. http://dx.doi.org/10.1111/j.1749-6632.1964.tb56313.x.

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18

Broussard, Craig L. "Hyperbaric Oxygenation and Wound Healing". Journal of Wound, Ostomy and Continence Nursing 30, n. 4 (luglio 2003): 210–16. http://dx.doi.org/10.1097/00152192-200307000-00008.

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19

Broussard, Craig L. "Hyperbaric oxygenation and wound healing". Journal of Vascular Nursing 22, n. 2 (giugno 2004): 42–48. http://dx.doi.org/10.1016/j.jvn.2004.03.001.

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20

Kol, S., e Y. Melamed. "Hyperbaric oxygenation for necrotizing fasciitis". American Journal of Obstetrics and Gynecology 168, n. 4 (aprile 1993): 1336. http://dx.doi.org/10.1016/0002-9378(93)90399-4.

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21

Mitrovic, A., S. Dragojevic-Dikic e T. Jovanovic. "P121b: Endometrium after hyperbaric oxygenation". Ultrasound in Obstetrics and Gynecology 22, S1 (2003): 104. http://dx.doi.org/10.1002/uog.586.

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22

Lynn, Michael, e William A. Friedman. "HYPERBARIC OXYGEN IN THE TREATMENT OF A RADIOSURGICAL COMPLICATION". Neurosurgery 60, n. 3 (1 marzo 2007): E579. http://dx.doi.org/10.1227/01.neu.0000255343.41206.6f.

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Abstract OBJECTIVE Hyperbaric oxygenation is a rarely used method of treatment for steroid-refractory radiation-induced edema after stereotactic radiosurgery. We present its successful implementation for a radiosurgical complication after the treatment of a deep, large arteriovenous malformation. We also review the literature on hyperbaric oxygenation for radiation-induced complications. CLINICAL PRESENTATION A 25-year-old man underwent radiosurgical treatment for a large arteriovenous malformation. Three years later, substantially smaller remaining nidus was retreated. Five months after that treatment, the patient developed edema around the nidus and hemiparesis. This problem was refractory to high-dose steroids. INTERVENTION The patient underwent a course of 25 hyperbaric oxygenation treatments. Within 1 month, the edema and hemiparesis had improved, allowing steroids to be tapered. A follow-up examination 1 year later revealed complete thrombosis of the arteriovenous malformation and minimal neurological deficit. CONCLUSION This technical case report adds to the few studies in the literature suggesting that hyperbaric oxygenation therapy, in conjunction with a slow steroid taper, is a reasonable addition to the treatment armamentarium for radiation-induced cerebral edema associated with clinically evident neurological deficits.
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Popovicheva, A. N., A. K. Martusevich, L. N. Sosnina, E. A. Galova, E. N. Fedulova, I. A. Neshchetkina e M. S. Vagin. "The effect of hyperbaric oxygenation on the state of blood rheology and hemostasis in children with inflammatory bowel diseases". Experimental and Clinical Gastroenterology, n. 6 (21 novembre 2022): 83–89. http://dx.doi.org/10.31146/1682-8658-ecg-202-6-83-89.

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Aim. To study the rheological properties of blood and platelet hemostasis in children with inflammatory bowel diseases before and after a course of hyperbaric oxygenation Materials and methods. Aggregation and deformability of erythrocytes, activation and aggregation of platelets were studied in 16 patients with Crohn's disease and 11 patients with ulcerative colitis age from 6 to 17 years. Similar indicators were studied after a course of hyperbaric oxygenation, carried out in a single-seat air-oxygen pressure chamber “BaroOx 1.0”. The course consisted of 5-8 daily sessions in the 1.3-1.4 ata during 40 minutes. Results. In pediatric patients with Crohn's disease and ulcerative colitis a significant violation of the rheological and hemostasiological properties of blood was revealed. After a course of hyperbaric oxygenation a significant decrease in the aggregation of erythrocytes, an increase in their deformability, and a decrease in the functional activity of platelets were noted. Conclusion. The use of hyperbaric oxygenation in children with inflammatory bowel diseases contributes to a significant correction of the rheological and hemostasiological properties of blood.
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Wolański, Władysław. "Research on the Possibility of Treating Streptococcal Infections with Hyperbaric Oxygenation". Polish Hyperbaric Research 70, n. 1 (1 marzo 2020): 43–46. http://dx.doi.org/10.2478/phr-2020-0003.

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AbstractThe aim of the study was to determine the effect of the application of hyperbaric oxygen therapy on the course of an infection with group A type T-3 hemolytic β streptococcus. Experiments were carried out on Porton white mice and in vitro blood plates. General and local infections with streptococci were induced in animals. The infected animals were treated with hyperbaric oxygenation. The lethal effect of infection was significantly inhibited using hyperbaric oxygenation on the first and second day following the infection.
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Wolański, Władysław, Kazimierz Ulewicz e Brunon Kierznikowicz. "Experimental studies on the treatment of streptococcal infections with hyperbaric oxygenation". Polish Hyperbaric Research 56, n. 3 (1 settembre 2016): 37–42. http://dx.doi.org/10.1515/phr-2016-0018.

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Abstract The article presents the results of research into the therapeutic effect of hyperbaric oxygenation on bacterial infections performed on an animal model. The studies were performed on Porton mice infected intraperitoneally with haemolysing streptococci and later subjected, over a 3-day period, to 5 exposures of hyperbaric oxygenation at a pressure of 2.8 ata. Depending on the research group, the treatment was commenced after 24, 48, 72 and 96 hours from the moment of infection. Some of the animals died during the experiment.8 and 12 days from the date of infection, selected animals of each group were put to death and subjected to post mortem examination. A statistically significant positive effect of hyperbaric treatment on the survival rate, as well as on the development of complications (liver abscesses), was observed in those animals where the hyperbaric oxygenation was applied at an early stage. In groups where the therapy was initiated later, no positive effect was noted, and the complications tended to develop more rapidly.
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Oliirova, O. S., A. A. Kozka e E. A. Volosenkova. "HYPERBARIC OXYGENATION AND ANTIOXIDANTS IN THE TREATMENT OF DEEP BURNS". Amur Medical Journal, n. 15-16 (2016): 96–97. http://dx.doi.org/10.22448/amj.2016.15-16.96-97.

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Cvachovec, K. "Hyperbaric oxygenation and covid-19 disease?" Anesteziologie a intenzivní medicína 32, n. 3 (26 luglio 2021): 172–73. http://dx.doi.org/10.36290/aim.2021.024.

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28

Nakada, Teruhiro. "Hyperbaric Oxygenation for Experimental Bladder Tumor". European Urology 14, n. 2 (1988): 145–49. http://dx.doi.org/10.1159/000472921.

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Akiya, Tohru, Teruhiro Nakada, Takashi Katayama, Kokichi Ota, Masaru Chikenji, Tokuyoshi Matsushita e Haruo Saito. "Hyperbaric Oxygenation for Experimental Bladder Tumor". European Urology 14, n. 2 (1988): 150–55. http://dx.doi.org/10.1159/000472922.

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Diaz, J., D. Sponseller, L. Brown, S. Williamson, M. P. Thomas e D. P. Guyton. "HYPERBARIC OXYGENATION FOLLOWING EXPERIMENTAL MYOCARDIAL INFARCTION". Critical Care Medicine 16, n. 4 (aprile 1988): 439. http://dx.doi.org/10.1097/00003246-198804000-00160.

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31

Nahas, Gabriel G. "CONTROL OF ACIDOSIS IN HYPERBARIC OXYGENATION". Annals of the New York Academy of Sciences 117, n. 2 (14 marzo 2007): 774–86. http://dx.doi.org/10.1111/j.1749-6632.1964.tb56327.x.

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32

Igarashi, Yoshikazu, Yukio Watanabe e Kanemasa Mizukoshi. "Middle Ear Barotrauma during Hyperbaric Oxygenation." Practica Oto-Rhino-Laryngologica 84, n. 10 (1991): 1393–98. http://dx.doi.org/10.5631/jibirin.84.1393.

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Savilov, P. "MECHANISMS OF THE THERAPEUTIC EFFECT OF HYPERBARIC OXYGEN ON THE GAS EXCHANGE FUNCTION OF THE LUNGS IN SARS-CO-2-ASSOCIATED PNEUMONIA". National Association of Scientists 1, n. 69 (11 agosto 2021): 10–21. http://dx.doi.org/10.31618/nas.2413-5291.2021.1.69.458.

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The article discusses some mechanisms of the therapeutic effect of hyperbaric oxygenation in COVID-19: the effect of hyperbaric oxygen on the contractility of endotheliocytes of pulmonary capillaries, thrombogenic and arthrombogenic potential of pulmonary vessels.
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34

Martusevich, A. K., A. N. Popovicheva, L. N. Sosnina, E. A. Galova, E. N. Fedulova e I. A. Neshchetkina. "The effect of hyperbaric oxygenation on the state of oxidative stress and the antioxidant system of blood in children with inflammatory bowel diseases". Experimental and Clinical Gastroenterology, n. 1 (25 marzo 2022): 45–49. http://dx.doi.org/10.31146/1682-8658-ecg-197-1-45-49.

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Aim. To study the level of oxidative stress and the state of antioxidant protection of blood in children with inflammatory bowel diseases before and after a course of hyperbaric oxygenation Materials and methods. Markers of oxidative stress (malondialdehyde of blood plasma and erythrocytes, ischemia-modified blood plasma albumin) and indicators of antioxidant blood defense (catalase and reduced erythrocyte glutathione) were studied in 16 patients with Crohn’s disease and 11 patients with ulcerative colitis aged 6 to 17 years, thiol groups of blood plasma). Similar indicators were studied after a course of hyperbaric oxygenation, carried out in a single-seat air-oxygen pressure chamber “BaroOx 1.0”. The course consisted of 5-8 daily sessions in the 1.3-1.4 ata regimen for 40 minutes. Results. In pediatric patients with Crohn’s disease and ulcerative colitis, a significant development of oxidative stress (an increase in the level of malondialdehyde in blood plasma and erythrocytes, ischemia-modified blood plasma albumin) and changes in antioxidant protection indicators were revealed. After a course of hyperbaric oxygenation, a significant decrease in the concentration of markers of oxidative stress and an increase in the antioxidant defense of the blood were noted. Conclusion. The use of hyperbaric oxygenation in children with inflammatory bowel diseases significantly reduces the manifestations of oxidative stress and intensifies the antioxidant defense of the blood.
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Balestra, Costantino, e Jacek Kot. "Oxygen: A Stimulus, Not “Only” a Drug". Medicina 57, n. 11 (25 ottobre 2021): 1161. http://dx.doi.org/10.3390/medicina57111161.

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Depending on the oxygen partial pressure in a tissue, the therapeutic effect of oxygenation can vary from simple substance substitution up to hyperbaric oxygenation when breathing hyperbaric oxygen at 2.5–3.0 ATA. Surprisingly, new data showed that it is not only the oxygen supply that matters as even a minimal increase in the partial pressure of oxygen is efficient in triggering cellular reactions by eliciting the production of hypoxia-inducible factors and heat-shock proteins. Moreover, it was shown that extreme environments could also interact with the genome; in fact, epigenetics appears to play a major role in extreme environments and exercise, especially when changes in oxygen partial pressure are involved. Hyperbaric oxygen therapy is, essentially, “intermittent oxygen” exposure. We must investigate hyperbaric oxygen with a new paradigm of treating oxygen as a potent stimulus of the molecular network of reactions.
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Becker, Axel, Thomas Kuhnt, Hendrik Liedtke, Andreas Krivokuca, Marc Bloching e Jürgen Dunst. "Oxygenation Measurements in Head and Neck Cancers during Hyperbaric Oxygenation". Strahlentherapie und Onkologie 178, n. 2 (1 febbraio 2002): 105–8. http://dx.doi.org/10.1007/s00066-002-0892-0.

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Skugarevsky, O. A., S. L. Melguy, D. P. Salivonchik, I. I. Popova, L. V. Kartun, E. V. Hodosovskaya, V. N. Sklema, V. S. Oborotov e L. I. Kudina. "«Biological price» for body perfection in eating disorders: aims and approach to homeostasis restoration under hyperbaric oxygenation therapy". Health and Ecology Issues, n. 1 (28 marzo 2008): 102–8. http://dx.doi.org/10.51523/2708-6011.2008-5-1-22.

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Dynamic of oxidative stress components (superoxid dismutase (SOD), catalase (CAT) and malon dialdehyde (MD)) as a markers of general stress reactivity due to eating disorders have been assessed during hyperbaric oxygenation therapy. Adaptive changes in the SOD and CAT activity revealed only in low-pressure regimen (0,03 MPа) by comparing with high-pressure (0,1 MPа) one. Low-pressure regimen provide spare influence on the antioxidant defense processes by protection from the SOD and CAT activity decline during hyperbaric oxygenation therapy.
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Beiran, I., P. Reissman, J. Scharf, Z. Nahum e B. Miller. "Hyperbaric Oxygenation Combined with Nifedipine Treatment for Recent-Onset Retinal Artery Occlusion". European Journal of Ophthalmology 3, n. 2 (aprile 1993): 89–94. http://dx.doi.org/10.1177/112067219300300207.

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We describe the results of early hyperbaric oxygenation combined with nifedipine treatment for central retinal artery occlusion, and explain the results pathophysiologically. We report four cases in which hyperbaric oxygenation therapy was applied in combination with nifedipine, eyeball massage, and glycerol for the treatment of central retinal artery occlusion. In two of the cases in which therapy was started less than 100 minutes after the acute onset of visual loss and one case in which therapy was started during the course of central arterial occlusion, considerable improvement in visual acuity was observed, while in the fourth case in which therapy was started six hours after the acute onset of visual loss, no improvement appeared. We conclude from these results that hyperbaric oxygenation therapy has a beneficial effect on the final visual outcome of central retinal artery occlusion, provided it is applied early enough. Further investigation is needed to fully define the nature and terms of this beneficial effect.
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Belic, Branislava, e Marko Cincovic. "Impact of oxygen toxic action on the erythrocyte membrane and possibility of estimating central nervous system function disturbances". Vojnosanitetski pregled 68, n. 7 (2011): 539–43. http://dx.doi.org/10.2298/vsp1107539b.

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Background/Aim. Prolonged exposure to hyperbaric oxygen leads to changes of erythrocytes shape as a consequence of toxic effects of oxygen on the erythrocyte membrane. The aim of this study was to examine the association between occurance of pathological forms of erythrocytes at different time from the start of hyperbaric oxygenation and the moment of convulsions occurrence, an interrelationship of different pathological forms of erythrocytes during exposure to hyperbaric oxygenation, as well as the correlation between the presence of ruptured erythrocytes and function of central nervous system (CNS) after completion of hyperbaric treatment. Methods. Sixty laboratory mice, Mus musculus, were exposed to the wholly-oxygen pressure of 3.5 absolute atmospheres (ATA). Blood was collected at the 32nd, 34th, 36th, 38th and 40th minutes after the exposure to oxygen. Pathological forms of erythrocytes were examined by electron microscopy. A moment of convulsions occurrence was registered in all animals. After decompression neurological examinations of experimental animals were perfomed. The Pearson's coefficient of correlation, and linear regression equations for the parameters outlined in the aim of the study were calculated. Results. Hyperbaric oxygen caused damages of erythrocytes at the 34th minute after beginning of the treatment. Various forms of abnormal red blood cells occured, and immediately before the occurrence of irreversible changes (erythrocyte membrane rupture) echinocyte shape was dominated. A significant correlation between the number of damaged red blood cells at 34th minute and their number at the 36th, 38th and 40th minute was found. Convulsions were diagnosed significantly earlier in mice with a greater number of damaged red blood cells (p < 0.01). There was a negative correlation between the number of irreversiblly damaged red blood cells (ruptured) at the 40th minute and neurological score in the studied animals (p < 0.05). Conclusion. The analysis of altered erythrocytes during hyperbaric oxygenation could predict a moment of seizures occurrence, and therefore the duration of the therapy with hyperbaric oxygen. Ehinocytes indicate impending rupture of red blood cells and a possible occurrence of seizures. An increased number of ruptured red blood cells may also even indicate the potential burden of CNS after cessation of hyperbaric oxygenation.
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40

Skiba, Małgorzata, e Agnieszka Pedrycz. "Influence of hyperbaric oxygenation and its use in urinary tract diseases". Polish Hyperbaric Research 56, n. 3 (1 settembre 2016): 25–32. http://dx.doi.org/10.1515/phr-2016-0016.

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Abstract In this publication, we adduce examples of the use of hyperbaric oxygen therapy in urinary tract diseases. Hyperbaric oxygen therapy has been proved to have a positive influence on the kidneys of animals with diabetes, sepsis or undergoing chemotherapy. In the literature, we can also find many examples of the use of hyperbaric therapy with good clinical outcomes in human patients with prostatic hypertrophy, pyelonephritis, and hemorrhagic cystitis. The first trials of this kind of treatment of urinary tract diseases were started at the end of the twentieth century. In spite of the promising results, and numerous reports on the effectiveness of this non-invasive method of treatment, it is not currently used on a regular basis. Because many factors such as time, multiple applications, the parameters used in the hyperbaric chamber as well as the medications taken by the patient affect the quality of the result, further studies are needed to make hyperbaric therapy more suitable and safer for each patient.
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41

Дроздов, В. А., В. Н. Сакович, Е. Ф. Сакович e К. С. Янушкевич. "Use of Hyperbaric Oxygenation in the Treatment of Eye Diseases". Офтальмология. Восточная Европа, n. 1 (4 maggio 2020): 80–88. http://dx.doi.org/10.34883/pi.2020.10.1.009.

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В патогенезе различных глазных заболеваний ишемические и гемодинамические изменения приводят к гипоксии, которая трансформирует клетки в состояние парабиоза. Гипоксия является одной из причин, нарушающих процессы биологического окисления, что может привести к развитию энергетической недостаточности клеток и тканей. За последнее время повысилась заинтересованность к немедикаментозным методам лечения гипербарической оксигенации, которая существенно снижает фармакологическую нагрузку на пациента, при этом активно влияет на патологический процесс и способствует улучшению функционального состояния глаз. По данным Американского общества подводной и гипербарической медицины, использование гипербарической оксигенации рекомендуется в лечении следующих глазных заболеваний: окклюзии артерий сетчатки, декомпрессионной болезни с глазными проявлениями, газовой эмболии сосудов глаза, орбитальной клостридиальной гангрены, орбитального мукоромикоза, а также при трансплантации кожи век или периорбитальной области. Данные заболевания имеют высокий доказательный уровень безопасности и эффективности использования гипербарической оксигенации при проведении комбинированного лечения. Дальнейшие исследования комплексного применения гипербарической оксигенации в лечении других глазных болезней позволят улучшить качество и снизить длительность лечения, а также повысить качество жизни пациентов. В данной статье собран литературный обзор исследований применения гипербарической оксигенации в лечении глазных болезней. In the pathogenesis of various eye diseases ischemic and hemodynamic changes leading to hypoxia, which transforms cells into a state of parabiosis. Hypoxia is one of the reasons that change the processes of biological oxidation, which can lead to the development energy deficiency of cells and tissues. Recently interest in non-drug methods of treatment like hyperbaric oxygenation has increased, because it significantly reduces the pharmacological load on the patient while actively affecting the pathological process and contributing to the improvement of the functional state ofthe eye. According to the American Society of Underwater and Hyperbaric Medicine, the use of hyperbaric oxygenation is recommended in the treatment of the following eye diseases: occlusion of the retinal arteries, decompression sickness with eye manifestations, arterial gas embolism of the eye vessels, ocular and periocular gas gangrene, orbital mucoromycosis, radiation optic neuropathy, periorbital reconstructive surgery. These diseases have a high evidence level of safety and effectiveness using hyperbaric oxygenation during combined treatment. Further studies of the integrated use of hyperbaric oxygenation in the treatment of other eye diseases should improve the quality of treatment, reduce the duration of treatment and improve the quality of life patients. This article contains a literature review of studies using hyperbaric oxygenation in the treatment of eye diseases.
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MENON, DOUGLAS NEUMAR, LETÍCIA TEIXEIRA, NATALHA BRISTOT PAUROSI e MARCIO EDUARDO BARROS. "Effects of heparin and hyperbaric oxygenation on necrosis reduction in an animal model for degloving injuries". Revista do Colégio Brasileiro de Cirurgiões 44, n. 1 (febbraio 2017): 64–71. http://dx.doi.org/10.1590/0100-69912017001014.

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ABSTRACT Objective: to evaluate the efficacy of the treatment with hyperbaric oxygen therapy or with topical and intralesional heparin in an animal model of degloving lesions. Methods: we conducted an experimental study with adult, male Wistar rats submitted to degloving of the left hind limb and divided into four groups according to the treatment: Group 1 (control) - without treatment; Group 2 (Heparin) - intralesional application at the time of surgery and topically, in the postoperative period, with heparin spray 10,000IU/mL; Group 3 (hyperbaric oxygenation) - daily sessions of 30 minutes in a hyperbaric chamber with 100% oxygen and 2 ATA pressure; Group 4 (positive control) - administration of a single dose of 45 mg/kg of intraperitoneal allopurinol. On the seventh day, we killed the animals, removed the cutaneous flaps and measured the total and necrotic areas, as well as computed the percentage of necrotic area. Results: the mean percentage of necrosis in the control group was 56.03%; in the positive control group it was 51.36% (p<0.45); in the heparin group, 42.10% (p<0.07); and in the hyperbaric oxygen therapy group, 31.58% (p<0.01) . Conclusion: both hyperbaric oxygen and heparin therapies were effective in reducing the percentage of necrosis in the model studied, although only the hyperbaric oxygenation showed statistical significance.
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43

Sakovych, V. M., e O. V. Aleksieieva. "Our Experience in the Treatment of Bacterial Keratitis". International scientific-practical journal Ophthalmology, n. 1 (12) (2021): 27–33. http://dx.doi.org/10.30702/ophthalmology31032021-12.1.27-33/835.

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Introduction. In recent years, the emergence of bacterial strains resistant to antibiotics used in medical practice significantly reduced the effectiveness of chemoprophylaxis and therapy. Following data indicates the need to search for new antibacterial drugs and ways of treating patients with bacterial keratitis. The aim of research is improvement of clinical parameters in patients with bacterial keratitis using hyperbaric oxygenation. Materials and Methods. We observed 68 patients (68 eyes) with bacterial keratitis aged 18 to 75 years. There were 36 men and 32 women. The patients were divided into 2 groups: main group (38 patients) and control group (30 patients). All the patients received antibiotic therapy, mydriatics, tissue-based products, vitamins. In addition, patients of the main group underwent hyperbaric oxygenation. The severity of the inflammatory response was evaluated using objective indicators: the presence and type of discharge into the conjunctival cavity, the severity of the mixed injection, corneal edema, the degree of inflammatory infiltration of the surface layers of the cornea. Results. The changes of clinical parameters in patients of the main and control groups were evaluated and scored (conjunctival discharge in the cavity, the severity of the mixed injection, corneal edema and inflammatory infiltration). The therapy contributed to faster disappearance of discharge into the conjunctival cavity and mixed injection, regression of edema, resorption of infiltrates (p <0.001). Conclusions. Hyperbaric oxygenation in comprehensive treatment of patients with bacterial keratitis is highly efficient, provides stable clinical and functional results in the main group compared with the control group. Keywords: bacterial keratitis, hyperbaric oxygenation, comprehensive treatment, clinical parameters in points.
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44

Бочкарева, N. Bochkareva, Кирюхина, S. Kiryukhina, Подсеваткин, V. Podsevatkin, Подсеваткина e S. Podsevatkina. "Study of quality of life in the patients with personality neurotic development". Journal of New Medical Technologies. eJournal 8, n. 1 (5 novembre 2014): 0. http://dx.doi.org/10.12737/6445.

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Objective: To study the therapeutic effects of mexidol, hyperbaric oxygenation and timogena in complex treatment of patients with neurotic personality development and its impact on quality of life of patients. Material and methods: The study included 142 patients with neurotic personality development. Patients of the first group were prescribed conventional therapy anxiolytic and antidepressant within 30 days. Patients of the second group were treated basic therapy and antioxidant immune correctors, sessions of hyperbaric oxygenation. Performance criteria for the final evaluation of the results of treatment were: reduction of the severity of psychiatric symptoms, improve mental and physical performance and social activity. Results: In patients with neurotic personality development identified physical and mental exhaustion, re-duced intentions, low productivity at work and social exclusion, which is reflected in low rates of quality of life in social relations and in the psychological realm. These symptoms on a background of traditional anxiolytic and antidepressant therapy didn’t cropped, but compounded undesirable actions of these drugs. Combined anxiolytic and antidepressant combination with hyperbaric oxygenation and antioxidant immune correctors demonstrate the effectiveness of the therapeutic effects of metabolic therapy, which is manifested in a significant improvement in physical, mental and social functioning of patients and improve their quality of life. Conclusions: The combination of paroxetine and diazepam with mexidol, hyperbaric oxygenation therapy, timogena can reduce the undesirable effects of antidepressants and benzodiazepine anxiolytics, increase efficiency of patients, their activity in communication, social inclusion and quality of life, indicating that the high efficacy and safety of this regimen.
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Babkina, A. V., M. Sh Khubutiya, O. A. Levina, A. K. Evseev, A. K. Shabanov, I. V. Goroncharovskaya e A. A. Medvedev. "Parameters of the oxidative-reduction system of the homeostasis in female transplant patients with tumors of the reproductive system treated with hyperbaric oxygen therapy". Transplantologiya. The Russian Journal of Transplantation 11, n. 4 (12 dicembre 2019): 290–300. http://dx.doi.org/10.23873/2074-0506-2019-11-4-290-300.

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Introduction. Studies on the effects of hyperbaric oxygenation have often been represented as animal model experiments. Currently, the number of studies on the use of hyperbaric oxygen therapy in the post-transplant period in humans is growing. The need in investigating the efficacy of hyperbaric oxygen therapy in the postoperative period in female transplant patient with tumors of the reproductive system is dictated by time.The aim of the study was to evaluate the efficacy of hyperbaric oxygen therapy in the complex treatment of transplant patients at an early stage of the postoperative period.Material and methods. We have studied the course of an early postoperative period in 8 female transplant patients with reproductive system tumors treated in N.V. Sklifosovsky Research Institute for Emergency Medicine, using hyperbaric oxygenation. The hyperbaric oxygen therapy sessions were provided in a single-patient hyperbaric chamber at 1.2–1.6 ATA for 40 minutes. The status of the redox homeostasis system was assessed based on the data of the platinum electrode open circuit potential measured in blood plasma by using the potentiometric method; and the blood plasma antioxidant activity was assessed by cyclic voltammetry.Results. The analysis of the results showed that there was a direct relationship indicating the positive effect of hyperbaric oxygen therapy on the balance status of the pro- and antioxidant systems of the body, and on the improvement of blood counts.Conclusion. The early inclusion of hyperbaric oxygen therapy in the complex treatment of transplant patients with tumors of the reproductive system contributes to a more rapid recovery of pro- and antioxidant systems of the body, blood counts.
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Gus'kov, Evgeniy P., Elena V. Mashkina, Nina I. Belichenko, Tatyana V. Varduni, Gleb E. Gus'kov, Tatyana P. Shkurat, Galina I. Volosovcova e Inna O. Pokudina. "Mutational processes in animals preadapted to oxidizing stress". Ecological genetics 7, n. 1 (15 marzo 2009): 41–48. http://dx.doi.org/10.17816/ecogen7141-48.

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Article is devoted to a problem of metabolic systems preadaptation an organism as a result of influence oxidizing stress, induced hyperbaric oxygenation (0,2 MPa), on newborn rats, and also an estimation of a degree and duration of preservation of a metabolic trace after that influences. Opportunities of increase stability animals to influence stress modes of oxidizing stress, induced hyperbaric oxygenation (0,5 MPa) after their preadaptation during the newborn period are considered. Mutational processes in different periods after preadaptation are investigated; changes of norm reaction to oxidizing stress in the posterity received from reciprocal crossings of preadapted rats are estimated.
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Sánchez, E. Cuauhtémoc. "Use of Hyperbaric Oxygenation in Neonatal Patients". Critical Care Nursing Quarterly 36, n. 3 (2013): 280–89. http://dx.doi.org/10.1097/cnq.0b013e318294e95b.

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Ueda, Takashi, Shoji Arikawa, Toshiyuki Nakazono, Shinichiro Wakisaka e Tetsuya Wada. "Hyperbaric oxygenation therapy for acute cerebral infarction." Nosotchu 14, n. 6 (1992): 627–32. http://dx.doi.org/10.3995/jstroke.14.627.

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Hutchison, James H., e Margaret M. Kerr. "TREATMENT OF ASPHYXIA NEONATORUM BY HYPERBARIC OXYGENATION". Annals of the New York Academy of Sciences 117, n. 2 (14 marzo 2007): 706–12. http://dx.doi.org/10.1111/j.1749-6632.1964.tb56318.x.

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50

Torbati, Dan. "Heparin effects during hyperbaric oxygenation in rats". Life Sciences 36, n. 2 (gennaio 1985): 147–51. http://dx.doi.org/10.1016/0024-3205(85)90093-1.

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