Letteratura scientifica selezionata sul tema "Hist014"

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Articoli di riviste sul tema "Hist014"

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Erdemir, Halil. "Mısır'ın Fransızlar Tarafından İşgali Örneğinde Uluslararası İlişkilerde Realizm". History Studies International Journal Of History 1, n. 1 (2009): 197–211. http://dx.doi.org/10.9737/hist_14.

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Balcı, Tamer. "İslam'ın Millileştirilmesinden Milliyetçiliğin Özelleştirilmesine: İslamiyet ve Türk Milli Kimliği". History Studies International Journal Of History 1, n. 1 (2009): 82–107. http://dx.doi.org/10.9737/hist_10.

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Altın, Hamza. "The İmportance of Ziya Gokalp for our Educational History". History Studies International Journal Of History Volume 2 Issue 2 (2024): 493–509. http://dx.doi.org/10.9737/hist_104.

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L. Menchinger, Ethan. ""'Gems for Royal Pofit': Prefaces and The Practice of Eighteenth-Century Ottoman Court History". History Studies International Journal Of History Volume 2 Issue 2 (2024): 127–51. http://dx.doi.org/10.9737/hist_114.

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Selçuk, Hava. "Cizye Vergisinin Kayseri Sancağında Uygulanması ve 1699 Terihli Cizye Beratı". History Studies International Journal Of History Volume 2 Issue 2 (2024): 85–99. http://dx.doi.org/10.9737/hist_124.

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Nazır, Bayram. "Dersaadet Chamber of Commerce and International Exhibitions". History Studies International Journal Of History 1, n. 1 (2009): 179–96. http://dx.doi.org/10.9737/hist_13.

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Güldüoğlu, Emine. "An Assessment on Property Sales in Kayseri According to The Şer'iye Sicilleri (1678-1679)". History Studies International Journal Of History Volume 2 Issue 2 (2024): 71–84. http://dx.doi.org/10.9737/hist_134.

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Ayar, Mesut. "The Ongoing İmpact Of The Most Dreadful Disease Of World History Plague In The Ottoman Empire In The Early 20th Century Within The Contexts Of 1900 Izmir And 1901 Istanbul Epidemics". History Studies International Journal Of History Volume 2 Issue 2 (2024): 173–88. http://dx.doi.org/10.9737/hist_141.

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Çolak, Songül. "The Statement of Ottoman Army in the 17.th Century According to the Aziz Efendi's Report". History Studies International Journal Of History Volume 2 Issue 2 (2024): 101–12. http://dx.doi.org/10.9737/hist_143.

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Köse, Osman. "The Official Document “Receipt”Given to Russia By Otoman State Pertaining to Crimea (1784)". History Studies International Journal Of History Volume 2 Issue 2 (2024): 353–62. http://dx.doi.org/10.9737/hist_144.

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Tesi sul tema "Hist014"

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Garciaz, Sylvain. "Conséquences cliniques et moléculaires de la marque H3K27 me3 HIST1 dans les leucémies aigües myéloïdes sans anomalies cytogénétiques". Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0429.

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Abstract (sommario):
De nombreuses altérations épigénétiques ont été décrites dans les leucémies aiguës myéloïdes (LAM). Nous avons récemment mis en évidence un enrichissement anormal en la marque histone H3K27me3, située sur 70 kb du cluster HIST1 (6p22) dans 50% des échantillons de patients atteints d'une LAM avec un caryotype normal (CN). Nous étudions dans ce travail, les conséquences cliniques et moléculaires de cette marque. H3K27me3 HIST1high est associé à 1) une meilleure survie des patients en analyse multivariée 2) la sous-expression du mRNA de plusieurs gènes histones (HIST1H1D, HIST1H2BG et HIST1H2BH) 3) un enrichissement fonctionnel en gènes associés à la réponse immunitaire ou inflammatoire, en faveur d’un engagement dans la différenciation granulocytaire, surexprssion confirmée pour trois de ces gènes (CYBB, FCN1 et CLEC4A) par RT-qPCR dans les blastes de patients H3K27me3 HIST1high 4) une diminution de la quantité absolue de protéine histone linker H1d par spectormétrie de masse et par Western blot et 5) une meilleure sensibilité à la différenciation induite par l'acide rétinoïque dans la lignée OCI-AML3 avec un KD de H1d (augmentation de l’expression des marqueurs de différenciation CD11B et CD11C, présence de granules intra-cytoplasmiques et expression des gènes CYBB et ITGAM). En conclusion, le biomarqueur H3K27me3 HIST1high est associé à une meilleure survie dans les LAM-CN NPM1mut, un phénotype plus différencié des blastes et une sous-expression génique et protéique de certains histones incluant le sous-type histone linker H1d. H1d semble être important dans la différenciation des blastes de LAM NPM1mut et pourrait constituer une cible thérapeutique
The epigenetic machinery is frequently altered in acute myeloid leukemia (AML). We previously described an abnormal histone H3K27me3 repressive enrichment covering 70 kb on the HIST1 cluster (6.p22). In the present work, we further studied the medical significance and the molecular impact of this new epigenetic biomarker. We observed that H3K27me3 HIST1high is associated with 1) a better patients' outcome in multivariate analysis, 2) a lower histone mRNA expression of several histone genes (HIST1H1D, HIST1H2BG and HIST1H2BH), 3) a mature granulocytic gene expression profile including immune or inflammatory responsive genes, (we confirmed the higher expression of three of these genes, CYBB, FCN1 and CLEC4A, using qPCR in the H3K27me3 HIST1high patients' samples), 4) a decrease in histone linker H1d absolute protein abundance by Mass spectrometry and by Western blot analyses and 5) a better retinoic acid sensitization of the H1d KD OCI-AML3 cell line (i.e. increase of CD11B and CD11C expression on cell surface, higher percentage of cytoplasmic granules and mRNA up-expression of two mature granulocytic genes, CYBB and ITGAM). To conclude, this study showed that epigenetic silencing of the HIST1 locus by the H3K27me3 mark is associated with a better outcome, but also a mature gene expression profile in the NPM1mut subgroup of patients. We suggested that H1d has an important role of histone linker expression in AML blast cell differentiation. This protein could constitute a new epigenetic target
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Li, Yichao. "Algorithmic Methods for Multi-Omics Biomarker Discovery". Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1541609328071533.

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Libri sul tema "Hist014"

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Acp Hist112 Truman State. Wadsworth, 2016.

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Acp Truman State Univ. Hist112. Wadsworth, 2015.

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Araújo, Francisco Miguel. História da educação em Vila Nova de Gaia. A cura di Cláudia Pinto Ribeiro. FLUP/CitCem, 2017. http://dx.doi.org/10.21747/9789898351708/hist2017.

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Harrison. Time & Place Hist1 Res Ancie. Prentice Hall (a Pearson Education company), 1992.

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Harrison. Time & Place Hist1 Res Tudor. Prentice Hall (a Pearson Education company), 1992.

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HIST4, Volume 1 (Book Only). Cengage Learning, 2015.

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Foresman, Scott. HIST0RY SOCAL SCIENCE 2006 TEXT 32-PACK GRADE K UNIT 4 LESSON 2. Pearson Scott Foresman, 2005.

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Foresman, Scott. HIST0RY SOCAL SCIENCE 2006 TEXT 32-PACK GRADE 1 UNIT 3 LESSON 3. Pearson Scott Foresman, 2005.

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Foresman, Scott. HIST0RY SOCAL SCIENCE 2006 TEXT 32-PACK GRADE 1 UNIT 4 LESSON 1. Scott Foresman, 2005.

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Foresman, Scott. HIST0RY SOCAL SCIENCE 2006 TEXT 32-PACK GRADE 2 UNIT 1 LESSON 1. Pearson Scott Foresman, 2005.

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Capitoli di libri sul tema "Hist014"

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Major, André. "Petite Hist01Re D’Une Obsession". In Canadian Writers in 1984, 207–12. University of British Columbia Press, 2007. http://dx.doi.org/10.59962/9780774857611-018.

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Atti di convegni sul tema "Hist014"

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A. Ross, Shawn. "Teaching Information Technology to a non-Technical Audience: A Graduate Course on IT for the Historical Profession". In 2003 Informing Science + IT Education Conference. Informing Science Institute, 2003. http://dx.doi.org/10.28945/2721.

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Abstract (sommario):
The graduate program in History at William Paterson University explicitly promotes itself as emphasizing information technology. HIST501: Information Technology for the Historical Profession, a course required of all entering graduate students, serves as a foundation for the IT literacy the program seeks to foster. Teaching HIST501 has proved challenging, however, due to the diverse interests and backgrounds of our students and a lack of integration with the broader graduate program. By structuring the course around an historical project—research, composition, and presentation of a thesis proposal— students immediately realize the relevance of IT to their research and teaching. Students learn IT applications and tools by using them to advance their proposal. By devoting class time to discussion of techniques for solving problems, while students learn the details of particular software packages on their own or through individual tutoring, a wide range of skill levels can be accommodated.
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