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Letteratura scientifica selezionata sul tema "Heterocyclic compounds"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 agosto 2024

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Articoli di riviste sul tema "Heterocyclic compounds"

Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo e Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles". Current Organic Synthesis 15, n. 8 (17 dicembre 2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstituted 2-amino-thiophene derivatives; sulfa- Michael/Henry and sulfa-Michael/aldol sequences to obtain polysubstituted tetrahydrothiophenes, and other heterocyclic reactions that allow synthesizing several functionalized sulfur-containing heterocycles such as thiazolidines, oxathiazinoles and thiazoles are presented and discussed. The use of such heterocyclics in subsequent reactions allows obtaining various bioactive compounds including the antiretroviral lamivudine which is one of the examples presented in this review.

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Romero-Hernández, Laura L., Ana Isabel Ahuja-Casarín, Penélope Merino-Montiel, Sara Montiel-Smith, José Luis Vega-Báez e Jesús Sandoval-Ramírez. "Syntheses and medicinal chemistry of spiro heterocyclic steroids". Beilstein Journal of Organic Chemistry 20 (24 luglio 2024): 1713–45. http://dx.doi.org/10.3762/bjoc.20.152.

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There is compelling evidence that incorporating a heterocyclic moiety into a steroid can alter its pharmacological and pharmacokinetic properties, driving intense interest in the synthesis of such hybrids among research groups. In this review, we present an overview of recent synthetic methodologies, spanning the period from 2000 to 2023, for the preparation of spiro heterocyclic steroids. The compounds surveyed encompass four-, five-, six-, and seven-membered heterocycles appended to various positions of steroidal backbones, with spirocycles containing oxygen, nitrogen, and sulfur atoms being predominant. The outlined synthetic procedures emphasize the pivotal steps for constructing the heterocycles, often accompanied by a detailed account of the overall synthesis pathway. The review encompasses innovative compounds, including bis-steroids linked by a spiro heterocycle and steroids conjugated to heterocyclic moieties containing three or more (hetero)cycles. Moreover, many compounds are accompanied by data on their biological activities, such as antiproliferative, antimalarial, antimicrobial, antifungal, steroid antagonist, and enzyme inhibition, among others, aimed at furnishing pertinent insights for the future design of more potent and selective drugs.

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Yadav, Shailendra, Sushma Singh e Chitrasen Gupta. "A CONCISE OVERVIEW ON HETEROCYCLIC COMPOUNDS EXHIBITING PESTICIDAL ACTIVITIES". International Journal of Advanced Research 9, n. 08 (31 agosto 2021): 989–1004. http://dx.doi.org/10.21474/ijar01/13352.

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Heterocyclic compounds are numerous and diverse group of organic compounds. Heterocycles are abundantly found in nature and express various physiological properties. Heterocycles are intricately linked to all aspects of life. There are many heterocyclic compounds currently known, and the number is constantly rising owing to extensive synthetic development and their applications. Heterocyclic compounds are used significantly in a number of areas, including biochemistry and medicinal chemistry, and some others. They are predominantly synthesized in agrochemical and pharmaceutical industries due to their potential biological activities. This review article focuses on recently synthesized heterocyclic compounds and their different pesticidal activities such as antifungal, antibacterial, antiviral, nematocidal, insecticidal, acaricidal, and herbicidal.

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Bhattacharya, Somenath, Soumallya Chakraborty, Rohan Pal, Sourav Saha, Bhaskar Ghosh, Chiranjit Mandal, Dr Amitava Roy e Dr Arin Bhattacharjee. "A Comprehensive Review on Pyrazole and It’s Pharmacological Properties". International Journal for Research in Applied Science and Engineering Technology 10, n. 9 (30 settembre 2022): 1769–74. http://dx.doi.org/10.22214/ijraset.2022.46924.

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Abstract: Heterocyclic chemistry is very important aspects in organic chemistry. Heterocyclic system consists of one or more heteroatoms like nitrogen, oxygen, sulphur, etc with hydrogen atoms. The system can be classified as saturated as well as non saturated system or hydrocarbons. Another classification of this ring system is divided in some categories like three-membered, four-membered, five-membered, six-memebered, seven-membered, fused heterocyclics etc. Some compounds under this cklassification are acidic or basic in nature. Examples of heterocyclic compounds are Pyrole, Furan, Thiophene, Pyridine, Quinoline, Isoquinoline, Indole, Purine, Pyrazole, etc. Pyrazole is very important under this heterocyclic ring sysyem. Pyrazole is five membered heterocyclics. Pyrazole is basic and unsaturated in nature due to presence of double bonds in their ring structure. When two nitrogen atoms are associated with five menbered heterocyclic ring in 1,2 positions called as Pyrazole structure. It is also known as 1,2-diazole. It is present in many drugs as well as organic compounds and Pharmaceutical compounds. The review study shown that the structure, physical and chemical properties, nomenclature, synthetic approaches, biological activities of Pyrazole heterocyclic ring structure

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Palaniappan, Saravana Priya. "Pharmacological Role of Heterocyclic Compounds in the Treatment of Alzheimer’s Disease: A Review". Journal of Phytopharmacology 11, n. 4 (15 agosto 2022): 289–94. http://dx.doi.org/10.31254/phyto.2022.11412.

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Alzheimer’s disease (AD) is a multifactorial neurological disease that mainly affects the old age people. Neuropathologically, AD is characterized by low level of acetylcholine, loss of synapses and neurons in certain brain regions, accumulation of extracellular amyloid beta peptide (Aβ) and phosphorylation of intracellular tau protein. Patients with AD are characterized by various symptoms such as memory deficits, depression, cognitive dysfunction and difficult to perform daily activities. Currently available drugs for the treatment of AD are used to treat symptomatic relief at an early stage, however the prolonged usage of the drugs may cause adverse side effects. To overcome this, development of drugs produced from natural products is considered as one of the promising alternatives for the treatment of AD. Among that heterocyclic compound play a major role in the development of therapeutic drugs against various disorders. An organic compound which is cyclic or non-cyclic consists of one or more atoms in their ring structure are known as heterocyclic compounds. These heterocyclic compounds occur both in natural and synthetic form and play a major role in the metabolism of all living cells. Most of the organic compounds used as drugs have a heterocyclic core in their skeleton. Nitrogenous bases such as purines and pyrimidines present in DNA, chlorophyll, vitamins contain heterocycle in their structure. Other compounds containing heterocycles are proline, morphine, furan, vinblastine, cephalosporin, penicillin etc. This review summarizes the nomenclature, classification, and the role of heterocyclic compounds in the treatment of Alzheimer's disease.

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Shaikh, Ansar R., Mazahar Farooqui, R. H. Satpute e Syed Abed. "Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’". Journal of Drug Delivery and Therapeutics 8, n. 6-s (21 dicembre 2018): 424–28. http://dx.doi.org/10.22270/jddt.v8i6-s.2156.

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Heterocyclic compounds have a role in most fields of sciences such as medicinal chemistry, biochemistry also another area of sciences. More than 90% of new drugscontain heterocycles and the interface between chemistry and biology, at which so much new scientific insight, discovery and application is taking place is crossed by heterocyclic compounds. Compounds derived from heterocyclic rings in pharmacy, medicine, agriculture, plastic, polymer and other fields.Most active heterocycles that have shown considerable biological actions as antifungal, anti-inflammatory, antibacterial, anticonvulsant, antiallergic, herbicidal, anticancer activity. There is always a strong need for new and efficient processes in synthesizing of new Heterocycles.Alum have been used as a novel catalyst in the synthesis of Schiff’s bases. Synthesized Schiff’s bases are free from use of ICH class 1 and Class 2 solvents and also free from structural alerts genotoxic impurities. This review highlights on various aspects of heterocyclic compounds with its biological activity & regulatory assessment based on the ‘International Regulatory Standards’. Keywords: Heterocycles. Nitrogen containing compounds Biological activity, History, Regulatory assessment, International Regulatory Standards

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Adak, Laksmikanta, e Tubai Ghosh. "Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles". Current Organic Chemistry 24, n. 22 (18 dicembre 2020): 2634–64. http://dx.doi.org/10.2174/1385272824999200714102103.

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Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed reactions have accomplished a noteworthy development in the synthesis of heterocycles. This review highlights some remarkable achievements in the iron-catalyzed synthesis of heterocyclic compounds published in the last five years.

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Olšovská, Jana, Karel Štěrba, Martin Slabý e Tomáš Vrzal. "Novel method for determination of heterocyclic compounds and their impact in brewing technology". KVASNY PRUMYSL 67, n. 2 (15 aprile 2021): 417–27. http://dx.doi.org/10.18832/kp2021.67.417.

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A new simultaneous method for determination of 16 heterocyclic compounds using SPE sample preparation and GC-MS determination was developed regarding increasing interest of the role of sensory active compounds in beer. LiChrolut® EN SPE columns proved to be optimal for both, a mixture of analytes with a different polarity and such complicated matrix as beer. Recoveries of individual analytes are about 100% except for three compounds (2-methylpyridine about 30%, maltol and furaneol about 50%); repeatability, uncertainty and LOQ are satisfactory for the method application. The method was used for monitoring of heterocyclic compounds formation during roasting, mashing, hop boiling and fermentation. To summarize, during roasting of malt, the concentration of oxygen heterocycle compounds (OHC) increases more rapidly in comparison with nitrogen heterocycles compounds (NHC) till a critical point where OHC starts to decrease and NHC starts to be formed sharper (with the exception of 2-acetylpyrrole which is similar to OHC). Finally, the total concentration of NHC during fermentation rapidly decreases whilst the OHC concentration is influenced by many factors, e.g., fermentation conditions and yeast strain.

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Shekarkhand, Marzieh, Karim Zare, Majid Monajjemi, Elham Tazikeh-Lemeski e Masoumeh Sayadian. "Computational study of heterocyclic anticancer compounds through nbo method". Nexo Revista Científica 35, n. 01 (6 aprile 2022): 367–81. http://dx.doi.org/10.5377/nexo.v35i01.13982.

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In the present study NBO method contain the HOMO and the LUMO energies are calculated for 10 different heterocycles anticancer drug using B3LYP/6-31G(d,p). Frontier molecular orbitals (HOMO and LUMO) and Molecular Electrostatic Potential map of the compound was produced by using the π stacking of structures and anticancer activity of molecules. The NBO analysis was suggested that the molecular system contains π- π interaction, strong conjugative interactions and the molecule become more polarized owing to the movement of π-electron cloud from donor to acceptor. NBO, HOMO and LUMO energies, were investigated and Anticancer activity of Aromatic Heterocyclic compounds was investigated by NBO study and result was compared with our previous study about NICS and S-NICS of these 10 anticancer drug. the HOMO/LUMO gap of the heterocycle anticancer drug is significantly different from each other. The NBO method is used in both symmetric and asymmetric molecules and provides accurate information on the aromatics of the compound, especially the heterocyclic rings. It also provides accurate information in protected areas. Molecule 8 has the highest amount of HOMO and therefore aromaticity among the studied compounds which confirms the result of molecular orbital examination.

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Murarka, Sandip, e Andrey Antonchick. "Metal-Catalyzed Oxidative Coupling of Ketones and Ketone Enolates". Synthesis 50, n. 11 (3 maggio 2018): 2150–62. http://dx.doi.org/10.1055/s-0037-1609715.

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Recent years have witnessed a significant advancement in the field of radical oxidative coupling of ketones towards the synthesis of highly useful synthetic building blocks, such as 1,4-dicarbonyl compounds, and biologically important heterocyclic and carbocyclic compounds. Besides oxidative homo- and cross-coupling of enolates, other powerful methods involving direct C(sp3)–H functionalizations of ketones have emerged towards the synthesis of 1,4-dicarbonyl compounds. Moreover, direct α-C–H functionalization of ketones has also allowed an efficient access to carbocycles and heterocycles. This review summarizes all these developments made since 2008 in the field of metal-catalyzed/promoted radical-mediated functionalization of ketones at the α-position.1 Introduction2 Synthesis of 1,4-Dicarbonyl Compounds3 Synthesis of Heterocyclic Scaffolds4 Synthesis of Carbocyclic Scaffolds5 Conclusion

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Tesi sul tema "Heterocyclic compounds"

Locke, Julie Myree, University of Western Sydney, College of Health and Science e School of Biomedical and Health Sciences. "Synthetic and conformational studies of hexahydropyrimidines and related heterocycles". THESIS_CHS_BHS_Locke_J.xml, 2003. http://handle.uws.edu.au:8081/1959.7/638.

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This thesis explores the synthesis and conformational behaviour of hexahydropyrimidines and related heterocycles, with particular emphasis on 5- hyrdohexahydropyrimidines. The conformational behaviour of these compounds was investigated using dynamic NMR spectroscopy, molecular modelling techniques and X-ray crystal structure analysis. The conformational behaviour of 5- hyrdohexahydropyrimidine, hexahydropyrimidine and their analogous oxygen compounds as well as a series of hexahydropyrimidines with various exocyclic substituents, were examined. The preferred conformations of all these compounds are attenuated by a combination of steric and electronic influences. These influences include intramolecular hydrogen bonding as well as anomeric and gauche interactions. The conformational behaviour of the selected seven membered benzodiazepine rings, which share structural characteristics with the six-membered 5- hyrdohexahydropyrimidines was also explored. The increased flexibility of the seven membered rings facilitates intramolecular hydrogen bonding, which in turn retards ring inversion in these systems
Doctor of Philosophy (PhD)

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Hu, Gang. "Conducting polymers from heterocyclic compounds". Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240331.

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Armugam, S. "Studies on N-Heterocyclic Compounds". Thesis, Indian Institute of Science, 1994. https://etd.iisc.ac.in/handle/2005/108.

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The thesis entitled "Studies on N-Hetero cyclic Compounds: (a) Reaction of 5,6,7,8-Tetrahydroisoquinolines with Vilsmeier Reagent and (b) Amide Induced in situ Alkylation of 5,6-Dihydroisoquinolines" is presented in two parts. Part I involves a study of the Vilsmeier reaction of 4-cyano-1,3-dihydroxy-5,6,7,8 tetrahydroisoquinoline derivatives, while Part II concerns the in situ alkylation of l-alkyl-4-cyano-3-methoxy-5,6- dihydroisoquinolines in presence of KNH2/liq.NH3.

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Armugam, S. "Studies on N-Heterocyclic Compounds". Thesis, Indian Institute of Science, 1994. http://hdl.handle.net/2005/108.

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Nyoni, Dubekile. "Application of the Baylis-Hillman methodology in the construction of novel heterocyclic derivatives". Thesis, Rhodes University, 2008. http://eprints.ru.ac.za/1134/.

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Miah, Soyfur. "The metallocarbene route to heterocyclic compounds". Thesis, Loughborough University, 1997. https://dspace.lboro.ac.uk/2134/26972.

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Wilson, Jennifer M. "Synthesis of biologically active heterocyclic compounds". Thesis, University of Glasgow, 2007. http://theses.gla.ac.uk/45/.

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More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are required that are more effective and selective. Nitrogen mustard alkylating agents crosslink DNA inhibiting transcription and replication. Use of the mustard pharmacophore as part of a macrocycle allows metal complexation and produces a prodrug. Hypoxic tumour cells have increased concentrations of reductase enzymes which could lead to reduction of the complex in situ and release of a cytotoxic drug. Human African Trypanosomiasis is commonly known as Sleeping Sickness and affects over 36 countries of sub-Saharan Africa. It is transmitted to humans by the tsetse fly which carries the parasitic subspecies Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Any compounds synthesised would also be tested to assess their potential as anti-parasitic agents. Parker synthesised a range of polyazamacrocycles. Testing of compound A in vitro gave highly efficient DNA crosslinking activity. Copper complexes were formed of the macrocycles and B was found to be 24 times more toxic against hypoxic cells than oxic cells thus exploiting tumour hypoxia and creating a selective drug. Jones synthesised a range of oxaazamacrocycles such as C which when tested in vitro exhibited comparable cross-linking activity to the azamacrocycles although it proved impossible to synthesise the corresponding copper complexes. It was decided to vary the leaving group on the alkylating arms to see if the DNA crosslinking results could be improved. Eight carbamates and the corresponding copper complexes were synthesised. The R-groups were alkyl and aromatic. Anti-cancer DNA crosslinking and hypoxia selectivity results were disappointing however, a number of compounds displayed significant activity when tested against T. brucei. A range of thiaazamacrocycles would complete the set of heteroatom-containing macrocycles (N, O, S) and might produce good DNA crosslinking results. It might also be possible to synthesise the corresponding copper complexes producing prodrugs. Six thiaazamacrocycles were synthesised and 2-hydroxyethyl arms were attached. However it proved impossible to isolate the desired alkylating agents with the 2-chloroethyl arms. In the body, the p53 protein activates the transcription of specific genes. In healthy cells, the levels of p53 have to be kept to a minimum to allow the normal running of the cell, e.g. growth and replication. This function is carried out by the HDM2 protein, which forms an auto-regulatory feedback loop with p53. In some tumours, the p53 function is disrupted due to genetic mutations of p53. However other tumours possess ‘wild type’ p53 – this type of p53 has lost the ability to respond to oncogenic stress due to over-expression of HDM2. Drugs that inhibit HDM2 should cause stabilisation of p53 and induce apoptosis in cancer cells. A small library of 5-deazaflavins were synthesised and biologically tested producing some interesting biological results.

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MacDonald, Ranald John. "Novel routes to heterocyclic Azo compounds". Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5787.

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The potential use of electron-deficient heterocyclic azo compounds as inkjet dyes was explored. 2-Nitrosopyridine could be used to form a series of azo compounds via the Mills’ reaction with electron-rich aromatic amines. Conditions for this process were optimised by varying solvent and pH. In the presence of ethers, 2-nitrosopyridine is quickly reduced to azoxypyridine. This reaction follows first order kinetics; diethyl and diisopropyl ether react at similar rates, whereas cyclic ethers such as THF are far slower. Organic bases such as Hunigs base were also found to promote formation of azoxypyridine. The mechanism of this reduction was studied. The electrochemistry of 2-nitrosopyridine and azoxypyridine was also explored. Using the optimised conditions for the Mills’ reaction, 2-nitrosopyridine not only reacts with electron-rich amines but also electron-deficient examples. The series was also expanded to include other heterocycles as well as pyridine via the corresponding heterocyclic nitroso compound. Other nitroso compounds prepared were 1- nitrosoisoquinoline, 2-nitrosopyrazine, 4-nitrosopyrimidine and 2-nitrosopyrimidine. The absorption maxima of azo compounds prepared from these precursors were found to correlate with the values for the corresponding azobenzenes. 2-Nitrosopyridine and 2-nitrosopyrimidine react with diamines to give monoazo products. These in turn could be diazotised and coupled with various components to give either bisazo or trisazo compounds. These dyes were tested for their ozone and light fastness properties. The bisazo examples were found to have good ozone fastness but poor light fastness. The pyrimidine examples only showed a slight improvement in ozone and light fastness compared to their pyridine analogue. 2,3-Phthalocyanines are important components in cyan dyes. New routes to precursors of these compounds were explored using flash vacuum pyrolysis (FVP).

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Jamalis, Joazaizulfazli. "Synthesis of heterocyclic containing oxygen compounds". Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529847.

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Lee, On-yi. "Synthesis of heterocycles via phenylseleno group transfer radical cyclization and chemoselective reductive amination promoted by InCl3". Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B3955756X.

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Libri sul tema "Heterocyclic compounds"

Petrov, Viacheslav A., a cura di. Fluorinated Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2009. http://dx.doi.org/10.1002/9780470528952.

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Hans, Suschitzky, Meth-Cohn Otto e Royal Society of Chemistry, a cura di. Heterocyclic chemistry. London: Royal Society of Chemistry, 1985.

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Krygowski, Tadeusz M., e Michał K. Cyrański, a cura di. Aromaticity in Heterocyclic Compounds. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-68343-8.

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Newkome, George R., a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1985. http://dx.doi.org/10.1002/9780470186701.

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Brown, D. J., R. F. Evans, W. B. Cowden e M. D. Fenn, a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1985. http://dx.doi.org/10.1002/9780470186770.

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Brown, D. J., a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1988. http://dx.doi.org/10.1002/9780470186893.

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Delia, Thomas J., e John C. Warner, a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1991. http://dx.doi.org/10.1002/9780470186909.

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Jones, Gurnos, e John V. Greenhill, a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1990. http://dx.doi.org/10.1002/9780470187043.

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Kathawala, F. G., Gary M. Coppola e Herbert F. Schuster, a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1990. http://dx.doi.org/10.1002/9780470187128.

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Coppola, Gary M., e Herbert F. Schuster, a cura di. Chemistry of Heterocyclic Compounds. Hoboken, NJ, USA: John Wiley & Sons, Inc., 1995. http://dx.doi.org/10.1002/9780470187135.

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Capitoli di libri sul tema "Heterocyclic compounds"

Sahu, Reema, Dakeshwar Kumar Verma e Chandrabhan Verma. "Heterocyclic Compounds". In Handbook of Heterocyclic Corrosion Inhibitors, 1–15. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003377016-1.

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Wang, Zerong. "Heterocyclic Compounds". In Amino Acids: Insights and Roles in Heterocyclic Chemistry, 1–37. New York: Apple Academic Press, 2023. http://dx.doi.org/10.1201/9781003329831-1.

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Alvárez-Builla, Julio, e José Barluenga. "Heterocyclic Compounds: An Introduction". In Modern Heterocyclic Chemistry, 1–9. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527637737.ch1.

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Paulus, Wilfried. "Heterocyclic N,S Compounds". In Microbicides for the Protection of Materials, 321–40. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2118-7_15.

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Brandsma, Lambert. "Metallation of Heterocyclic Compounds". In Preparative Polar Organometallic Chemistry, 127–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-61517-7_6.

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Ahluwalia, V. K. "Stereochemistry of Some Heterocyclic Compounds". In Stereochemistry of Organic Compounds, 447–75. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84961-0_16.

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Azam, Amir, e Subhash Mohan Agarwal. "Heterocyclic Lead Compounds Against Amebiasis". In Amebiasis, 565–81. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-55200-0_33.

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Tabaković, Ibro. "Anodic synthesis of heterocyclic compounds". In Topics in Current Chemistry, 87–139. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/3-540-61454-0_71.

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Ata, Athar, e Samina Naz. "Synthesis of Bioactive Heterocyclic Compounds". In Greener Synthesis of Organic Compounds, Drugs and Natural Products, 137–50. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003089162-8.

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Joule, J. A., K. Mills e G. F. Smith. "Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis". In Heterocyclic Chemistry, 463–78. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_26.

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Atti di convegni sul tema "Heterocyclic compounds"

Fadil MOUSA, Enaam, e Ibtissam Khalifa JASSIM. "SYNTHESIS ,CHARACTERIZATION AND BIOLOGICAL ACTIVITY STUDY OF SOME HETEROCYCLIC COMPOUNDS". In IV.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress4-18.

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Heterocycles are an important class of organic compounds because of their applications in medicines and industrial fields. Therefore our study included preparation of these compound such as oxazepine and quinazoline rings, which were prepared through two steps: The first step included the reaction of the Schiff bases derived from sulfamethaxazole (1-4) with each of phthalic anhydride and 3- nitrophthalic anhydride for the preparation of oxazepines (5-12) .While the second step included the preparation of quinazoline compounds (13-16) from the reaction of Schiff bases (1-4) with anthranilic acid using dry benzene as a medium and solvent for the reaction. All prepared compounds were characterized by using infrared,proton- nuclear magnetic resonance, mass techniques and melting points, and their purity was determined by thin layer chromatography technique also screened the biological activity of some of these prepared compounds by using two types of bacteria Gram-positive and negative . The results showed that these compounds have a good inhibition against these organisms

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Nowak, Kacper, Michal Grzelczak, Boguslaw Szlachetko, Piotr Swiatek, Malgorzata Strzelecka, Lukasz A. Sterczewski, Edward F. Plinski e Stanislawa Plinska. "Terahertz investigations on some bi-heterocyclic compounds". In 2016 21st International Conference on Microwave, Radar and Wireless Communications (MIKON). IEEE, 2016. http://dx.doi.org/10.1109/mikon.2016.7492097.

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Mangalagiu, Violeta, Dumitrela Diaconu, Costel Moldoveanu, Gheorghita Zbancioc, Ramona Danac, Dorina Amariucai-Mantu, Vasilichia Antoci e Ionel Mangalagiu. "Hybrid and chimeric nitrogen heterocycles with biological activity". In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab01.

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Nitrogen heterocycles, especially azine and azole derivatives, are highly valuable scaffolds in medicinal chemistry, being the core components of a large variety of drugs with variously biological activity such as antiplasmodial and antimalarial, antitubercular, antibacterial, antifungal, anticancer, analgesic, antidepressant, anxiolytics, antihypertensive, anticoagulants, diuretics, etc. As a result, obtaining of such entities continues to arouse a strong interest from academia and industry. As part of our ongoing research in the area of nitrogen heterocyclic derivatives, we present herein some representative results obtained by our group in the field of hybrid and chimeric azahetrocycles compounds with antimicrobial and anticancer activity. Chemistry, anticancer, antibacterial, antifungal and antituberculosis activity of compounds is presented. Some of the hybrid and chimeric structures possess a good anticancer and/or antimicrobial activity.

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Pausch, Axel E., Thomas Geelhaar, Eike Poetsch e Ulrich Finkenzeller. "New fluorinated heterocyclic compounds for improved FLC mixtures". In SPIE/IS&T 1992 Symposium on Electronic Imaging: Science and Technology, a cura di Paul S. Drzaic e Uzi Efron. SPIE, 1992. http://dx.doi.org/10.1117/12.60381.

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Ariunbold, Gombojav O., Bryan Semon, Surpiya Nagpal e Yuri Rostovtsev. "Cooperative Emissions from Hydrogen-Bonded Heterocyclic Organic Compounds". In CLEO: Applications and Technology. Washington, D.C.: OSA, 2020. http://dx.doi.org/10.1364/cleo_at.2020.aw4k.4.

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Biliavska, Liubov, Yulia Pankivska, Olga Povnitsa, Svitlana Zagorodnya, Ganna Gudz, Nadiia Pikun e Yuriy Shermolovich. "Antiviral Activity of Fluorinated Heterocyclic Compounds". In 2nd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2016. http://dx.doi.org/10.3390/ecmc-2-a019.

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Stanovnik, Branko. "3-Dimethylaminopropenoates and Related Compounds in the Synthesis of Heterocyclic Systems and Heterocyclic Amino Acids". In The 4th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01783.

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Drokin, R., D. Gazizov, D. Tiufiakov, E. Voinkov, E. Gorbunov, E. Ulomsky, G. Rusinov e V. Rusinova. "POTASSIUM SALTS OF NITROCARBONYL COMPOUNDS IN THE SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS". In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m749.aks-2019/187-189.

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Redda, Kinfe Ken, Madhavi Gangapuram, Mohammad A. Ghaffari, Suresh Eyunni, Nelly Mateeva e Bereket Mochona. "Abstract 2229: Synthesis of heterocyclic compounds as anticancer agents." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2229.

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Schrader, Sigurd K., Paolo Imperia, Norbert Koch, Guenther Leising e B. Falk. "Organic light-emitting devices based on new heterocyclic compounds". In SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, a cura di Zakya H. Kafafi. SPIE, 1999. http://dx.doi.org/10.1117/12.372711.

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Rapporti di organizzazioni sul tema "Heterocyclic compounds"

Allcock, Harry R. Strained Inorganic Heterocyclic Compounds and their Conversion to Macrocycles and High Polymers. Fort Belvoir, VA: Defense Technical Information Center, ottobre 1991. http://dx.doi.org/10.21236/ada241414.

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Klubek, B. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds). Office of Scientific and Technical Information (OSTI), marzo 1990. http://dx.doi.org/10.2172/7019091.

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Brel, Valery K. Development of the New Approaches in Designing of Fluoroorganic Derivatives Sulfur (Unsaturated, Heterocyclic, Aromatic Molecular Systems and Polyfunctional Organic Compounds). Fort Belvoir, VA: Defense Technical Information Center, novembre 2005. http://dx.doi.org/10.21236/ada447113.

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Klubek, B., e D. Clark. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds): Final report, March 1--December 31, 1987. Office of Scientific and Technical Information (OSTI), marzo 1988. http://dx.doi.org/10.2172/6462019.

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Klubek, Brian. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds): Final report, January 1--December 31, 1988. Office of Scientific and Technical Information (OSTI), marzo 1989. http://dx.doi.org/10.2172/6177644.

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Author, Not Given. (Comparison of the activity of subsurface and surface microorganisms and their anaerobic transformation of heterocyclic compounds): Progress report, July 1, 1987--June 30, 1989. Office of Scientific and Technical Information (OSTI), gennaio 1989. http://dx.doi.org/10.2172/6025469.

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Ozekin, K., R. D. Noble e C. A. Koval. A theoretical analysis of the extraction of heterocyclic organic compounds from an organic phase using chemically mediated electrochemically modulated complexation in ion exchange polymer beads. Office of Scientific and Technical Information (OSTI), gennaio 1991. http://dx.doi.org/10.2172/6181074.

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Adams, Richard D. Studies of the Transformations of Sulfur Containing Heterocycles by Transition Metal Cluster Compounds. Final Report, June 1, 1995 - October 31, 1999. Office of Scientific and Technical Information (OSTI), maggio 2001. http://dx.doi.org/10.2172/803362.

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