Articoli di riviste sul tema "Heroin dependence"

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1

Maqsood, Niaz, Bushra Akram, Naima Luqman e Rizwana Amin. "HEROIN DEPENDENCE;". Professional Medical Journal 21, n. 06 (10 dicembre 2014): 1161–65. http://dx.doi.org/10.29309/tpmj/2014.21.06.2241.

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Objective: To determine the frequency and level of family support in Heroin Dependent patients presenting with 1st treatment and also the patients presenting with relapses. Study design: A descriptive study. Place & duration of study: The study was conducted in the Department of Psychiatry & Behavioral Sciences, Nishtar Hospital, Multan from September, 2013 to December, 2013. Subjects & methods: The sample consisted of 50 consecutive inpatients presenting with Heroin Dependence. They were interviewed and Family support Scale (FSS) was administered to know the level of support in heroin dependent patients. Results: Results showed that 20% patients relapsed 3 times while 38% had more than three times relapses among whome 30% patients have family support, but 70% have very low level and family support decreased with increasing number of replace. Conclusions: We concluded that higher level of family support was during in the 1st treatment of Heroin Dependence and family support decreased as the number of relapses increased.
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dos Santos, Monika, e Fred van Staden. "Heroin Dependence Recovery". Journal of Psychology in Africa 18, n. 2 (gennaio 2008): 327–37. http://dx.doi.org/10.1080/14330237.2008.10820206.

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Merrill, Joseph O., e Ron Jackson. "Treatment of Heroin Dependence". Annals of Internal Medicine 134, n. 2 (16 gennaio 2001): 165. http://dx.doi.org/10.7326/0003-4819-134-2-200101160-00020.

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Hyman, Mark H. "Treatment of Heroin Dependence". Annals of Internal Medicine 134, n. 8 (17 aprile 2001): 714. http://dx.doi.org/10.7326/0003-4819-134-8-200104170-00016.

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O'Connor, Patrick G., e David A. Fiellin. "Treatment of Heroin Dependence". Annals of Internal Medicine 134, n. 8 (17 aprile 2001): 714. http://dx.doi.org/10.7326/0003-4819-134-8-200104170-00017.

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Lintzeris, Nicholas. "Prescription of Heroin for the Management of Heroin Dependence". CNS Drugs 23, n. 6 (maggio 2009): 463–76. http://dx.doi.org/10.2165/00023210-200923060-00002.

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Santiago Rivera, Olga J., Jennifer R. Havens, Maria A. Parker e James C. Anthony. "Risk of Heroin Dependence in Newly Incident Heroin Users". JAMA Psychiatry 75, n. 8 (1 agosto 2018): 863. http://dx.doi.org/10.1001/jamapsychiatry.2018.1214.

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&NA;. "Buprenorphine effective for heroin dependence". Inpharma Weekly &NA;, n. 1376 (marzo 2003): 10. http://dx.doi.org/10.2165/00128413-200313760-00022.

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Snow, Diane. "Update on Heroin Dependence Research". Journal of Addictions Nursing 19, n. 1 (2008): 35–38. http://dx.doi.org/10.1080/10884600801897122.

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Haasen, Christian, Uwe Verthein, Peter Degkwitz, Juergen Berger, Michael Krausz e Dieter Naber. "Heroin-assisted treatment for opioid dependence". British Journal of Psychiatry 191, n. 1 (luglio 2007): 55–62. http://dx.doi.org/10.1192/bjp.bp.106.026112.

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BackgroundHeroin-assisted treatment has been found to be effective for people with severe opioid dependence who are not interested in or do poorly on methadone maintenance.AimsTo study heroin-assisted treatment in people on methadone who continue intravenous heroin and in those who are heroin dependent but currently not in treatment.MethodIn an open-label multicentre randomised controlled trial, 1015 people with heroin dependence received a variable dose of injectable heroin (n=515) or oral methadone (n=500) for 12 months. Two response criteria, improvement of physical and/or mental health and decrease in illicit drug use, were evaluated in an intent-to-treat analysis.ResultsRetention was higher in the heroin (67.2%) than in the methadone group (40.0%) and the heroin group showed a significantly greater response on both primary outcome measures. More serious adverse events were found in the heroin group, and were mainly associated with intravenous use.ConclusionsHeroin-assisted treatment is more effective for people with opioid dependence who continue intravenous heroin while on methadone maintenance or who are not enrolled in treatment. Despite a higher risk, it should be considered for treatment resistance under medical supervision.
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Wodak, Alex. "The current status of heroin prescription treatment for heroin dependence". Expert Opinion on Drug Safety 4, n. 5 (settembre 2005): 815–19. http://dx.doi.org/10.1517/14740338.4.5.815.

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STANHOPE, JOHN M., KENNETH H. CURRY e RAVI NAYER. "HEROIN DEPENDENCE: INPATIENT DETOXIFICATION WITH CLONIDINE". Australian Alcohol/Drug Review 4, n. 1 (gennaio 1985): 56–61. http://dx.doi.org/10.1080/09595238580000081.

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Vasile, D., M. D. Gheorghe, R. Ciurea e S. Paraschiv. "Antisocial personality disorder-heroin-dependence comorbidity". European Neuropsychopharmacology 12 (ottobre 2002): 392. http://dx.doi.org/10.1016/s0924-977x(02)80651-4.

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Schellekens, A., T. Oosteren, T. Knuijver, R. J. verkes e M. Belgers. "Treatment of heroin dependence with ibogaine". European Psychiatry 33, S1 (marzo 2016): S10—S11. http://dx.doi.org/10.1016/j.eurpsy.2016.01.799.

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BackgroundThe use of the hallucinogen ibogaine as an anti-addiction agent has been described in several case reports, dating back to the eighties. The anti-addiction properties of ibogaine have been confirmed in a large body of animal work. Ibogaine has been shown to be effective in reducing withdrawal severity and substance use for a variety of substances, including cocaine and opiates. Animal studies also show some potentially dangerous adverse reactions, including cerebellar toxicity and potential cardiac effects. While pharmacological treatment options for opiate and cocaine dependence are still limited, ibogaine assisted treatment might be a promising new option. Therefore more systematic studies on its toxicity and efficacy are warranted. In our studies we address these two research questions: is ibogaine treatment for opiate dependence safe and effective for treating opiate withdrawal and relapse prevention? A secondary objective is to explore the pharmacokinetic properties of ibogaine.MethodsAnimal work: first we performed a systematic review and meta-analysis of animal studies on ibogaine. Thirty studies were included in the systematic review, of which 27 could be analyzed in meta-analysis. Human studies: fifteen opiate dependent patients will be treated with ibogaine (10 mg/kg), on top of treatment as usual. Ibogaine toxicity will be assessed through close monitoring with electrocardiography, with QTc prolongation as main outcome measure, repeated assessments of ataxia using the (SARA) and observation of psychotic symptoms by using the Delirium Observations Scale (DOS). Ibogaine efficacy will be measured, using repeated evaluations of opiate withdrawal severity (Subjective Opiate Withdrawal Scale: SOWS; Objective Opiate Withdrawal Scale: OOWS), craving intensity (using a Visual Analogue Scale) and substance use, with a six-month follow-up. Clinical observations in ibogaine treated individuals will be compared with a cohort of opiate dependent patients treated with a rapid detoxification procedure. Both acute and long-term effects will be linked with serum ibogaine and noribogaine levels.ResultsAnimal work: overall, ibogaine reduced drug self-administration, particularly during the first 24 hours after administration. Ibogaine had no effect on drug-induced conditioned place preference. Ibogaine administration resulted in motor impairment in the first 24 hours after supplementation, and cerebral cell loss even weeks after administration. Data on ibogaines effect on cardiac rhythm as well as on its neuropharmacological working mechanisms are limited. Human studies: human data are still being collected. Treatment of the first patients confirmed strong effects of ibogaine on heart rhythm (QTc prolongation) and ataxia, while the opiate withdrawal symptoms were relatively mild. The first observations on the clinical effect of ibogaine on craving and substance use will also be shared.ConclusionsBased on our meta-analysis of animal data, there is strong evidence that ibogaine is effective in reducing drug self-administration in animals. This warrants further studies into the clinical efficacy of ibogaine in substance dependent patients in reducing craving and substance use. Our first clinical experiences in a limited number of patients confirm that ibogaine treatment may be effective in reducing opiate withdrawal, but can potentially have transient cardiac and cerebellar toxicity.Disclosure of interestThe authors have not supplied his declaration of competing interest.
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Johnson, Rolley E., e Jeffrey C. McCagh. "Buprenorphine and Naloxone for Heroin Dependence". Current Psychiatry Reports 2, n. 6 (dicembre 2000): 519–26. http://dx.doi.org/10.1007/s11920-000-0012-8.

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Long, Elizabeth C., Radka Kaneva, Georgi Vasilev, F. Gerard Moeller e Jasmin Vassileva. "Neurocognitive and Psychiatric Markers for Addiction: Common vs. Specific Endophenotypes for Heroin and Amphetamine Dependence". Current Topics in Medicinal Chemistry 20, n. 7 (23 aprile 2020): 585–97. http://dx.doi.org/10.2174/1568026620666200131124608.

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Background: The differential utility of neurocognitive impulsivity and externalizing/ internalizing traits as putative endophenotypes for dependence on heroin vs. amphetamine is unclear. Objective: This exploratory study aims to determine: (1) whether neurocognitive impulsivity dimensions and externalizing/internalizing traits are correlated between siblings discordant for heroin and amphetamine dependence; and (2) which of these associations are common across substances and which are substance- specific. Methods: Pearson correlations between individuals with ‘pure’ heroin and amphetamine dependence and their unaffected biological siblings (n = 37 heroin sibling pairs; n = 30 amphetamine sibling pairs) were run on 10 neurocognitive measures, 6 externalizing measures, and 5 internalizing measures. Sibling pair effects were further examined using regression. Results: Siblings discordant for heroin dependence were significantly correlated on delay aversion on the Cambridge Gambling Task, risk-taking on the Balloon Analogue Risk Task, sensation seeking, and hopelessness. Siblings discordant for amphetamine dependence were significantly correlated on the quality of decision-making on the Cambridge Gambling Task, discriminability on the Immediate Memory Task, commission errors on the Go/No Go Task, trait impulsivity, ADHD and anxiety sensitivity. Conclusion: Dimensions of impulsivity and externalizing/internalizing traits appear to aggregate among siblings discordant for substance dependence. Risk-taking propensity, sensation seeking and hopelessness were specific for heroin sibling pairs. Motor/action impulsivity, trait impulsivity, and anxiety sensitivity were specific to amphetamine sibling pairs. Decisional/choice impulsivity was common across both heroin and amphetamine sibling pairs. These findings provide preliminary evidence for the utility of neurocognitive impulsivity and externalizing/ internalizing traits as candidate endophenotypes for substance dependence in general and for substance-specific dependencies.
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Hall, Wayne D., e Alex Wodak. "Is naltrexone a cure for heroin dependence?" Medical Journal of Australia 171, n. 1 (luglio 1999): 9–10. http://dx.doi.org/10.5694/j.1326-5377.1999.tb123488.x.

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Bhardwaj, Akansha, Sidharth Arya, Sunila Rathee e Rajiv Gupta. "Elderly male with late-onset heroin dependence". Journal of Geriatric Mental Health 8, n. 1 (2021): 51. http://dx.doi.org/10.4103/jgmh.jgmh_12_21.

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Pereska, Zanina, Cvetanka Bozinovska, Cedo Dimitrovski, Koco Cakalarovski, Andon Chibishev, Milka Zdravkovska, Aleksandra Babulovska e Daniela Janicevic. "Heroin Dependence Duration Influences the Metabolic Parameters". Journal of Addiction Medicine 6, n. 4 (dicembre 2012): 304–10. http://dx.doi.org/10.1097/adm.0b013e31826bd76c.

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Das, Gautam. "Chronic Heroin Dependence Leading to Adrenal Insufficiency". Case Reports in Endocrinology 2014 (2014): 1–2. http://dx.doi.org/10.1155/2014/461816.

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Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.
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Kleber, Herbert D. "Pharmacologic Treatments for Heroin and Cocaine Dependence". American Journal on Addictions 12 (12 ottobre 2003): S5—S18. http://dx.doi.org/10.1111/j.1521-0391.2003.tb00552.x.

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Ritter, Alison. "Buprenorphine for the treatment of heroin dependence". Drug and Alcohol Review 20, n. 1 (marzo 2001): 5–7. http://dx.doi.org/10.1080/0959523020035240.

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Kleber, Herbert D. "Pharmacologic Treatments for Heroin and Cocaine Dependence". American Journal on Addictions 12, n. 2 (gennaio 2003): S5—S18. http://dx.doi.org/10.1080/10550490390210083.

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Reisinger, Marc. "Buprenorphine as new treatment for heroin dependence". Drug and Alcohol Dependence 16, n. 3 (dicembre 1985): 257–62. http://dx.doi.org/10.1016/0376-8716(85)90050-x.

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Chawarski, Marek C., Mahmud Mazlan e Richard S. Schottenfeld. "Heroin dependence and HIV infection in Malaysia". Drug and Alcohol Dependence 82 (aprile 2006): S39—S42. http://dx.doi.org/10.1016/s0376-8716(06)80007-4.

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Hulse, Gary K., Noella Morris, Diane Arnold-Reed e Robert J. Tait. "Improving Clinical Outcomes in Treating Heroin Dependence". Archives of General Psychiatry 66, n. 10 (1 ottobre 2009): 1108. http://dx.doi.org/10.1001/archgenpsychiatry.2009.130.

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Rowan, Amy B., Paul J. Fudala e James Mulligan. "The medical management of adolescent heroin dependence". Current Psychiatry Reports 2, n. 6 (dicembre 2000): 527–30. http://dx.doi.org/10.1007/s11920-000-0013-7.

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Minhas, Meenu, e Francesco Leri. "The Effect Of Heroin Dependence On Resumption Of Heroin Self-Administration In Rats". Drug and Alcohol Dependence 138 (maggio 2014): 24–31. http://dx.doi.org/10.1016/j.drugalcdep.2014.01.007.

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Chaturvedi, Santosh K. "NARCOTIC WITHDRAWAL FEATURES IN BUPRENORPHINE AND HEROIN DEPENDENCE". Analgesia 1, n. 4 (1 gennaio 1995): 351–54. http://dx.doi.org/10.3727/107156995819563258.

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YANG, Ling, Jianxun ZHANG e Xin ZHAO. "Attentional Bias for Drug Cues in Heroin Dependence". Advances in Psychological Science 21, n. 12 (13 dicembre 2013): 2174–83. http://dx.doi.org/10.3724/sp.j.1042.2013.02174.

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Galkin, V. A. "P03.409 Basic remission of heroin dependence: Complex approach". European Psychiatry 15, S2 (ottobre 2000): 433s—434s. http://dx.doi.org/10.1016/s0924-9338(00)94816-8.

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Kanof, Philip D., Marvin J. Aronson, Robert Ness, Kenneth J. Cochrane, Thomas B. Horvath e Leonard Handelsman. "Levels of opioid physical dependence in heroin addicts". Drug and Alcohol Dependence 27, n. 3 (maggio 1991): 253–62. http://dx.doi.org/10.1016/0376-8716(91)90008-m.

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Wei, S. G., Y. S. Zhu, J. H. Lai, H. X. Xue, Z. Q. Chai e S. B. Li. "Association between heroin dependence and prodynorphin gene polymorphisms". Brain Research Bulletin 85, n. 3-4 (maggio 2011): 238–42. http://dx.doi.org/10.1016/j.brainresbull.2011.02.010.

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Darke, S., e J. Ross. "Polydrug dependence and psychiatric comorbidity among heroin injectors". Drug and Alcohol Dependence 48, n. 2 (novembre 1997): 135–41. http://dx.doi.org/10.1016/s0376-8716(97)00117-8.

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Agrawal, Arpana, Michael T. Lynskey e Elliot C. Nelson. "Shattered childhoods and the genetics of heroin dependence". Addiction 108, n. 4 (18 marzo 2013): 671–73. http://dx.doi.org/10.1111/add.12043.

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Nelson, Elliot C., Michael T. Lynskey, Andrew C. Heath, Naomi Wray, Arpana Agrawal, Fiona L. Shand, Anjali K. Henders et al. "ANKK1, TTC12, and NCAM1 Polymorphisms and Heroin Dependence". JAMA Psychiatry 70, n. 3 (1 marzo 2013): 325. http://dx.doi.org/10.1001/jamapsychiatry.2013.282.

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Leung, Janni, Gary C. K. Chan, Samuel X. Tan, Caitlin McClure-Thomas, Louisa Degenhardt e Wayne Hall. "State-Level Prevalence and Associates of Opioid Dependence in the USA". International Journal of Environmental Research and Public Health 19, n. 7 (23 marzo 2022): 3825. http://dx.doi.org/10.3390/ijerph19073825.

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Traditionally, opioid-related disease burden was primarily due to heroin use. However, increases in extra-medical (or non-medicinal use of prescription opioids; NMPOs) use has precipitated the current overdose epidemic in North America. We aim to examine the state-level prevalence of heroin and NMPO dependence and their associations with opioid-related mortality and state-level socio-demographic profiles. Data were pooled from the 2005–2014 National Survey on Drug Use and Health (NSDUH). We examine opioid-related mortality from CDC WONDER (Cause of Death database) by the past year prevalence of DSM-IV heroin and NMPO dependence, by age and sex, and their associations with state-level socio-demographic characteristics from census data. State-level rates of heroin dependence were associated with opioid-related death rates in young and mid-aged adults, while rates of NMPO dependence were associated with opioid-related death rates across all ages. The prevalence of heroin dependence was positively associated with state-level GDP/capita and urbanity. State-level NMPO dependence prevalence was associated with higher unemployment, lower GDP/capita, and a lower high-school completion rate. The prevalence of heroin and NMPO dependence are associated with a broad range of geographical and socio-demographic groups. Taking a wider view of populations affected by the opioid epidemic, inclusive interventions for all are needed to reduce opioid-related disease burden.
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Law, F. "Review: levomethadyl acetate hydrochloride improves retention in treatment and reduces heroin use in heroin dependence". Evidence-Based Mental Health 5, n. 4 (1 novembre 2002): 107. http://dx.doi.org/10.1136/ebmh.5.4.107.

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González-Sáiz, Francisco, Antònia Domingo-Salvany, Gregorio Barrio, Albert Sánchez-Niubó, M. Teresa Brugal, Luís de la Fuente e Jordi Alonso. "Severity of Dependence Scale as a Diagnostic Tool for Heroin and Cocaine Dependence". European Addiction Research 15, n. 2 (2009): 87–93. http://dx.doi.org/10.1159/000189787.

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Wodak, Alex, e Robert Graham. "Naltrexone implants as treatment for heroin dependence: Part II". Addiction Biology 10, n. 2 (giugno 2005): 202. http://dx.doi.org/10.1111/j.1369-1600.2005.tb00270.x.

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Ross, Joanne, Maree Teesson, Shane Darke, Michael Lynskey, Robert Ali, Alison Ritter e Richard Cooke. "Short-term Outcomes for the Treatment of Heroin Dependence". Addictive Disorders & Their Treatment 5, n. 3 (settembre 2006): 133–43. http://dx.doi.org/10.1097/01.adt.0000210717.33564.a8.

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Franken, Ingmar H. A., Linda Y. Kroon, Reinout W. Wiers e Anita Jansen. "Selective cognitive processing of drug cues in heroin dependence". Journal of Psychopharmacology 14, n. 4 (luglio 2000): 395–400. http://dx.doi.org/10.1177/026988110001400408.

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TUCKER, THAMIZAN K., ALISON J. RITTER, CLAIRE MAHER e HENRY JACKSON. "Naltrexone maintenance for heroin dependence: uptake, attrition and retention". Drug and Alcohol Review 23, n. 3 (settembre 2004): 299–309. http://dx.doi.org/10.1080/09595230412331289464.

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Fiellin, David A., Michael V. Pantalon, Juliana P. Pakes, Patrick G. O'Connor, Marek Chawarski e Richard S. Schottenfeld. "Treatment of heroin dependence with buprenorphine in primary care". American Journal of Drug and Alcohol Abuse 28, n. 2 (1 gennaio 2002): 231–41. http://dx.doi.org/10.1081/ada-120002972.

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Gordon, Susan M., Frank Mulvaney e Amy Rowan. "Characteristics of Adolescents in Residential Treatment for Heroin Dependence". American Journal of Drug and Alcohol Abuse 30, n. 3 (1 gennaio 2004): 593–603. http://dx.doi.org/10.1081/ada-200032300.

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Kim, Yung Su, Mei Yang, Wai-Kin Mat, Shui-Ying Tsang, Zhonghua Su, Xianfei Jiang, Siu-Kin Ng et al. "GABRB2 Haplotype Association with Heroin Dependence in Chinese Population". PLOS ONE 10, n. 11 (12 novembre 2015): e0142049. http://dx.doi.org/10.1371/journal.pone.0142049.

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Fudala, P. J. "Buprenorphine improved treatment retention in patients with heroin dependence". Evidence-Based Medicine 8, n. 5 (1 settembre 2003): 150. http://dx.doi.org/10.1136/ebm.8.5.150.

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Chen, Chia-Hsiang, Chia-Chun Huang e Ding-Lieh Liao. "Association Analysis of GABRB3 Promoter Variants with Heroin Dependence". PLoS ONE 9, n. 7 (15 luglio 2014): e102227. http://dx.doi.org/10.1371/journal.pone.0102227.

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Kalsi, Gursharan, Jack Euesden, Jonathan R. I. Coleman, Francesca Ducci, Fazil Aliev, Stephen J. Newhouse, Xiehe Liu et al. "Genome-Wide Association of Heroin Dependence in Han Chinese". PLOS ONE 11, n. 12 (9 dicembre 2016): e0167388. http://dx.doi.org/10.1371/journal.pone.0167388.

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Krupitsky, E., E. E. Zvartau e G. Woody. "S.09.03 Long acting naltrexone implants for heroin dependence". European Neuropsychopharmacology 19 (settembre 2009): S192. http://dx.doi.org/10.1016/s0924-977x(09)70234-2.

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