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Letteratura scientifica selezionata sul tema "Hepatitis B"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 31 luglio 2024

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Articoli di riviste sul tema "Hepatitis B"

1

Jain, Ravi, e Ashok Yadav. "Hepatitis B Versus Hepatitis C in Blood Donors". Annals of Applied Bio-Sciences 4, n. 1 (gennaio 2017): A8—A13. http://dx.doi.org/10.21276/aabs.2017.1306.

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2

Billah, Mustansar, Syed Muhammad Raza Shah e Muhammad Mujtaba Hashir. "HEPATITIS B AND HEPATITIS C". Professional Medical Journal 25, n. 08 (9 agosto 2018): 1245–51. http://dx.doi.org/10.29309/tpmj/18.4766.

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3

Salam, Abdul, Bilqis Aslam Baloch, Naseer Khan, Ghulam Sarwar e Masoom ,. "SEROPREVALENCE OF HBsAg (HBS) AND ANTI-HCV". Professional Medical Journal 21, n. 04 (7 dicembre 2018): 766–70. http://dx.doi.org/10.29309/tpmj/2014.21.04.2424.

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Background: Hepatitis is the inflammation of liver caused by infectious and noninfectiousagents. Hepatitis B and C are inflammations of liver caused by the viruses which are themajor public health problems worldwide and the incidence is even more in our country.Objective: Objective of the study was, 1). To estimate the prevalence of hepatitis B and hepatitisC viruses infected persons among the general population coming to BMC Hospital. 2). To pointout the more affected area of Baluchistan. 3). To produce awareness in the people. 4). To bringthis issue in Government notice. Method: The data was obtained from the patients of BMCHQuetta in which one step test kits were used first and the positive cases were confirmed by ELISA.Results: Out of 46319 samples tested (both indoor & outdoor patients), 3078 (6.64%) werepositive. From overall positive samples 1631(3.52%) were HBs positive and 1447(3.12) sampleswere positive for HCV and 2 patients were positive for both HBs Ag and anti HCV. Conclusions:Prevalence of Hepatitis B is more comparing to Hepatitis C in this province. Prevalence of bothHepatitis B and Hepatitis C was high in Naseerabad district of Baluchistan Great care should beexercised during shaving, dental treatment, surgical procedures and blood transfusions. Policymessage: - Media should be used by National Hepatitis Control Programme of Pakistan toeducate the public about hazards of unscreened blood transfusion. Blood screening for HepatitisB and C infections should be made mandatory at all blood banks.

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4

DAUD, SEEMA, IRAM MANZOOR e NOREEN RAHAT HASHMI. "PREVENTION OF HEPATITIS B". Professional Medical Journal 14, n. 04 (12 ottobre 2007): 634–38. http://dx.doi.org/10.29309/tpmj/2007.14.04.4829.

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Objective: To assess the knowledge and practice of first year MBBS students, for the prevention ofHepatitis B. Design: Descriptive study. Place and Duration of study: The study was conducted at Lahore Medical &Dental College, Lahore. The data was collected in two weeks in December, 2006. Methodology: A total of 50 studentswere recruited using a non probability random sampling technique, through the lottery method. A pre-tested structuredquestionnaire was administered to collect information about the knowledge and practice of students about theprevention of hepatitis B. Data was presented in the form of simple tables and graphs. Results: Out of 50 students,majority (96%) responded that it was a disease of liver. Regarding knowledge about the communicability of HepatitisB, 78% said it was communicable, 19% assumed that it was water borne. Other responses included spread via bloodtransfusion (28%), through use of injection (21%), close physical contact (8%) and un-hygienic conditions (18%). Forprevention of Hepatitis B, the more common responses were, provision of clean water (24%), improvement in hygiene(27%), restriction to single sex partner (6%), avoidance of sharing syringes and needles (19%), screening blood beforetransfusion (9%) and vaccination (15%). The high risk group was identified as the poor people living in unhygienicconditions (34%), surgeons (32%), barbers (12%), Intravenous drug users (8%), recipient of blood transfusion (6%)and uneducated people (6%). Only 1 respondent (2%) said that sex workers could be at risk of getting this disease.When inquired about their vaccination status, 66% of students admitted to have been vaccinated against Hepatitis B,while 34% of have not been vaccinated. Conclusion: The present study concludes that there is lack of awarenessamong the medical students entering into the profession about the hazards of Hepatitis B, its routes of spread and itsmodes of prevention. Similarly, all the students were not vaccinated against Hepatitis B, which made them veryvulnerable to this disease.

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5

Cano Pina, MB, CM Águila Gordo, P. Dabán López, MP Chas Garibaldi e B. Mirón Pozo. "New therapeutic approaches in Hepatitis B and Hepatitis D". Revista Andaluza de Patología Digestiva 46, n. 6 (2 gennaio 2024): 607–9. http://dx.doi.org/10.37352/2023466.3.

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Resumen La perforación del tracto gastrointestinal (GI) por ingesta de cuerpos extraños (huesos, palillos dentales, dentaduras, etc.) es poco prevalente, su diagnóstico es difícil y tardío principalmente debido a que los pacientes no suelen recordar la ingesta de los mismos. A nivel radiológico supone igualmente un reto, pues suelen ser objetos sutiles no visibles en radiografías, siendo la prueba de elección la TC. Ante una sospecha clínica o radiológica de perforación por cuerpo extraño, el tratamiento quirúrgico y antibiótico debe llevarse a cabo lo antes posible. Presentamos un caso clínico de una perforación intestinal secundaria a la ingesta de un palillo dental.

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6

Estévez Escobar, M. "New therapeutic approaches in Hepatitis B and Hepatitis D". Revista Andaluza de Patología Digestiva 46, n. 5 (30 ottobre 2023): 258–68. http://dx.doi.org/10.37352/2023465.3.

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Resumen El virus de la hepatitis B y el virus de la hepatitis D ocasionan un espectro variable de enfermedades hepáticas, desde cuadros asintomáticos hasta hepatitis fulminante o hepatitis crónica. Debido a que, en su forma crónica, la enfermedad puede tener consecuencias fatales sobre el huésped por desarrollo de cirrosis, disfunción hepática y desarrollo de hepatocarcinoma, es importante el diagnóstico precoz para iniciar un tratamiento que cambie la historia natural de la enfermedad, mejorando así el pronóstico del sujeto. En la actual revisión, se recorren las opciones disponibles de tratamiento en hepatitis B así como las novedades terapéuticas que persiguen obtener, no solo la supresión viral, sino la curación funcional. Además, se describe el actual escenario terapéutico en hepatitis D y el impacto que podrán tener sobre su manejo las nuevas moléculas en investigación, especialmente, Bulevirtide.

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7

Nayak, Akshatha P., Insha Firoz, Ravindra Prabhu, Jayanth Nayak, Veena NK e Megha Nagaraj Nayak. "Development of Immunity to Hepatitis B Virus Following Hepatitis B Vaccination in Hemodialysis Patient". Annals of International Medical and Dental Research 9, n. 2 (aprile 2023): 20–23. http://dx.doi.org/10.53339/aimdr.2023.9.2.4.

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Background: Hepatitis B infection is common in Dialysis population. Hemodialysis patients have high risk of hepatitis B virus transmission not only due to frequent blood or blood product transmission, decreased response to Hepatitis B vaccine and length on hemodialysis but also due to their immunosuppressed state. Hepatitis B vaccination has the potential to reduce the risk of HBsAg infection in dialysis units. Effective vaccination, blood donor screening, the use of erythropoietin and the isolation of HBV carriers have successfully regulated HBV infection in hemodialysis units (1). This study aims to assess the immunity to HBV the seroconversion of HBsAg infection in hemodialysis unit. This retrospective observational study evaluated serological markers, hepatitis B vaccination status and co morbidities which can affect the immunity levels of patients undergoing hemodialysis. The patient’s data were collected from laboratory investigations and patient record for analysis. Out of 153 CKD-5D patients on maintenance hemodialysis, 39 patients had anti HBs titer <10U/ml, 30 patients had anti HBs titer between 10-100U/ml, 38 patients had anti HBs titer between100-1000 U/ml, 21 patients had anti HBs titer >1000U/ml and 24 patients didn’t check their titer value. Hypertension was the common co morbidity followed by anaemia and diabetes mellitus.

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8

Tobokalova, S. T., D. S. Bekenova, G. M. Zairova, Z. Sh Nurmatov, Zh N. Nazarbaeva e Zh T. Aytieva. "Epidemiological features of acute and chronic hepatitis B in the Kyrgyz Republic over the 20-year period (1997-2017)". Kazan medical journal 99, n. 6 (15 dicembre 2018): 986–93. http://dx.doi.org/10.17816/kmj2018-986.

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Aim. To determine epidemiological features of acute and chronic viral hepatitis B in the Kyrgyz Republic over the period 1997-2017. Меthоds. Analysis was performed on data bases of the National accounting forms on treated cases of acute and chronic hepatitis B cumulated by the Medical Information Centre of the Ministry of Health of Kyrgyz Republic for the period of 1997 to 2017 as well as 384 medical records of patients with chronic hepatitis B treated in the Hepatologic Centre “Tsadmir”. Results. In the Kyrgyz Republic among all acute cases of acute viral hepatitides, hepatitis A comprises 60.5 %, hepatitis B - 16.9 %, the ratio of unverified non-A non-C viral hepatitis - 15.2%. With the introduction of HBV vaccination of children (2000) and improvement of infectious control in healthcare settings, a decline of acute HBV incidence is observed - from 26.7 0/0000 to 5.3 0/0000 due to the decrease of acute hepatitis B among children and adolescents to isolated cases, adults from risk groups. The highest incidence of acute hepatitis B is recorded in Osh and Bishkek, in Jalal-Abad and Chuy Regions. This can be explained by that in the southern and northern capitals of the Kyrgyz Republic and in the near lying areas with high population density, access to laboratory and instrumental methods of diagnosis of viral hepatitides is better, along with the higher awareness of its inhabitants regarding the prevention compared to other regions. At the same time an increase of chronic hepatitis B incidence is observed. Predominant modes of transmission are medical-parenteral exposure and household contact (60.9 %), with frequent formation of family clusters (23.8 %). Imperfections were found in the early detection, reporting and accounting of cases of chronic viral hepatitides as well as in examination of hepatitis B virus carriers. Conclusion. The performed analysis of the incidence and prevalence of acute and chronic hepatitis B in the Kyrgyz Republic allowed assessing the dynamics of the epidemiologic situation in the country regarding this disease, revealed shortcomings in the detection and examination of viral hepatitis B carriers, contributed to development of a new guide for epidemiological surveillance of viral hepatitides.

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9

Viana, Daniel Rodrigues, Nathalia Mundoco Veloso, Osvaldo Carvalho Neto, Nicolas Garcia Papacosta, Gabriel Martins Nunes e Virgílio Ribeiro Guedes. "Hepatite B e C: diagnóstico e tratamento". Revista de Patologia do Tocantins 4, n. 3 (26 settembre 2017): 73. http://dx.doi.org/10.20873/uft.2446-6492.2017v4n3p73.

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INTRODUÇÃO: As hepatites virais são consideradas as principais doenças hepáticas, podendo levar a quadros mais graves, como a cirrose e o carcinoma hepatocelular, tornando-se um importante problema de saúde pública. Tem distribuição global com áreas de altos índices de endemicidade, sobretudo em países asiáticos. Os principais agentes envolvidos são os vírus da hepatite A, B, C, D, E. O vírus da hepatite B e C se destacam nesse meio devido à grande capacidade de cronificação. As formas de transmissão são basicamente através do contato com fluidos corporais infectados, através de transfusões sanguíneas, uso de drogas injetáveis, transmissão vertical, etc. METODOLOGIA: Trata-se de um artigo de revisão no qual, a partir das palavras “hepatite B” e “hepatite C”, foi realizado busca por periódicos nos bancos de dados: PubMed, Scielo, Portal Periódicos CAPES e Google acadêmico. CONCLUSÃO: As hepatites B e C podem se apresentar apenas de forma aguda, ou podem se cronificar. O diagnóstico geralmente é realizado tardiamente, pois, na grande maioria dos casos apresenta-se oligossintomáticas ou até mesmo assintomática. O diagnóstico é feito através de exames sorológicos e quantificação viral através do PCR. O tratamento é basicamente sintomático, porem nos casos crônicos, é indicado uso de medicações, como interferons peguilhados e análogos de nucleosideos. Palavras-chave: Hepatites virais; Hepatite B; Hepatite C. INTRODUCTION: Viral hepatitis are considered as one of the major liver diseases, being able to lead more severe outcomes, such as cirrhosis and hepatocellular carcinoma becoming an important public health problem. It has global distribution with areas of high endemicity, especially in Asian countries. The main agents involved are hepatitis A virus, B, C, D, E. The hepatitis B and C viruses stand out in the middle of a chronicling ability. As the transmission forms are basically through contact with infected body fluids, through blood transfusions, injecting drug use, vertical transmission, etc. METHODOLOGY: This is a review article, from the words "hepatitis B" and "Hepatitis C", was carried out by search for journals in databases: PubMed, Scielo, Portal Periodicos CAPES and Google academic. CONCLUSION: The hepatitis B and C can either be only a form of acute, or can be chronic. Therefore, the diagnosis is often late, since in the vast majority of cases it is oligosymptomatic or even asymptomatic. The diagnosis is made through serological tests and viral quantification through PCR. The treatment is basically with symptomatic, such as pegged interferon’s and nucleoside analogs. Keywords: Viral hepatitis; Hepatitis B; Hepatitis C.

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10

Shahbaz, Tazeem, Ghulam Farid, Raja Sajjad Asghar e Abdul Rashid. "HEPATITIS B AND C". Professional Medical Journal 22, n. 11 (10 novembre 2015): 1383–89. http://dx.doi.org/10.29309/tpmj/2015.22.11.859.

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Background and Aims: The working conditions of Health care workers (HCW’S)expose them for a constant threat of contracting and spreading hepatitis B (HBV) and C virus(HCV) not only to their patients but family members as well. The aim of this study was to assessthe knowledge and attitude toward hepatitis B and C infection among the health-care workersand correlate the level of awareness to their behavior towards prevention of the disease. StudySettings: The study was conducted in Rashid Latif medical college and its two affiliated hospitals(Arif memorial teaching hospital and Hameed Latif Hospital). Study Design: Descriptive crosssectional study. Methodology: A closed ended questionnaire was designed which consistsof questions for evaluating the knowledge and attitude of the participants regarding hepatitisB and C infection. Sampling was done by convenient method. 350 participants took part inthe study, which includes physicians, nurses and lab Technicians. Using the SPSS 16, we didstatistical analysis. Results: Total 350 health care workers filled the forms. 52.6 %( 184) of themwere nurses with 25.7% (90) physicians, and Lab workers were 21.7 %( 74). The mean age ofthe participants was 25.9 years with a range from 17-59 years. The service length of 73.2% ofhealth care workers was noted to be 1-5 year. (97.7%) participants know about hepatitis B andC. 88.6% identified blood and blood products, needles and sharps and 68.6% marked sexualintercourse routes of transmission. 56% gave opinion that Hepatitis B and C is a noso-comialinfection. 70.3% reported that both infections are widely transmitted like HIV/AIDS. Almost all ofthe participants (83.7%) mentioned that they are in a position to acquire these infections becauseof their duty with patients 88% of the respondents reported vaccination against Hepatitis B asa tool of prevention. Proper disposal of sharps, a needle and blood product as a preventingmeasure was also written by 88%of participants. A lot of them believe that transmission of theseinfections can be prevented by avoiding needle/sharps injury (73.7%) and casual sex (61.1%).82.9 mentioned wearing of gloves while in contact with patients and 80.6% said that adequatedisposal of sharps are the best ways of prevention. Complete vaccination for the hepatitis Bwas reported by 47.9 %( 174) with 36 %( 126) was partially vaccinated and 14.8 %( 52) were notvaccinated at all. No specific reason was identified for lack of vaccination. It is noted that morefemales (87.7%) and physician (88.9%) and Nurses (88.2%) have completed the vaccinationschedule than the Lab. Technicians (75%). Conclusion: There is a need of extensive healtheducation campaign for training of HCWs to control and prevent the spread of these infections.

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Più fonti

Tesi sul tema "Hepatitis B"

1

Gerlach, Jochen. "Sequenzanalysen von Hepatitis-B-Virusvarianten bei fulminanter Hepatitis B und Hepatitis D". [S.l.] : [s.n.], 1999. http://www.sub.uni-hamburg.de/disse/321/Gerlach.pdf.

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2

Valente, Vanderleia Barbaro. "Estudo da distribuição dos marcadores sorológicos das hepatites B e C entre doadores de sangue do Hemocentro de Ribeirão Preto, SP". Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/17/17139/tde-29052003-193717/.

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Este estudo, que envolveu todos os doadores de sangue (25.891) que compareceram pela primeira vez ao Hemocentro de Ribeirão Preto, de junho de 1996 a junho de 2001, teve os seguintes objetivos: 1) Estudar a positividade de marcadores sorológicos das hepatites B e C em testes da triagem dos doadores. 2) Analisar o fluxo dos doadores positivos para os marcadores das hepatites B e C ao Ambulatório de Hepatites (AH) do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto. 3) Estimar a prevalência de infecção atual ou pregressa pelos vírus das hepatites B e C entre os doadores, através da análise dos resultados de testes confirmatórios para essas doenças. 4) Avaliar a importância da determinação da transaminase glutâmico-pirúvica (TGP) como marcador indireto de infecção pelos vírus das hepatites B e/ou C. Foram levantados dados registrados no Hemocentro, no Núcleo de Vigilância Epidemiológica (NVE) e no AH, coletando-se informações referentes ao doador, ao tipo de doação e ao resultado de teste da triagem sorológica (HBsAg, anti-HBc, anti-HCV, TGP, anti-HIV, anti-HTLV, doença de Chagas e sífilis). Foram estudados ainda: os resultados dos testes de repetição realizados no Hemocentro dos doadores positivos para os marcadores das hepatites B e C na triagem sorológica; o comparecimento ao NVE; e a confirmação, no AH, dos resultados para esses marcadores. A população dos doadores foi composta majoritariamente por homens (83,6%) e indivíduos de 26 a 45 anos de idade (64,0%). Predominaram as doações vinculadas (85,4%), e as maiores motivações foram solicitação e estímulo familiar ou de amigos. Os valores da prevalência, nos testes da triagem sorológica, foram iguais a 0,63% (IC95%: 0,54 0,72), para o HBsAg e 1,15% (IC95%: 1,02 1,28), para o anti-HCV. O total de doadores positivos que deveriam ser avaliados no AH, sofreu uma perda de 55,5% entre os suspeitos de ter hepatite B e de 58,7% entre os suspeitos de ter hepatite C, totalizando 266 doadores perdidos quanto ao acompanhamento. Os valores da prevalência, nos testes confirmatórios, foram iguais a 0,22% (IC95%: 0,16 0,28), para a hepatite B, e 0,31% (IC95%: 0,24 0,38), para a hepatite C. As co-positividades entre os valores de TGP e os marcadores de hepatites, nos testes de triagem sorológica, foram de 8,8%, para o vírus C, e de 0,5%, para o vírus B, indicando que a determinação dessa enzima não auxilia na seleção de doadores em bancos de sangue.
This study, which involved all blood donors (25.891) that attended the Blood Center of Ribeirão Preto for the first time from June 1996 to June 2001 had the following objectives: 1) To study the positiveness for hepatitis B and C serologic markers in donors screening tests. 2) To analyze the flow of positive donors for hepatitis B and C markers to the Hepatitis Ambulatory (HA) in the Clinical Hospital of the Faculty of Medicine of Ribeirão Preto of the University of São Paulo. 3) To estimate the predominance of present or former infection by hepatitis B and C viruses among donors, by analyzing results of screening tests that confirm these diseases. 4) To evaluate the importance of determining the glutamic-piruvic transaminase (GTP) as an indirect marker of infection by hepatitis B and C viruses. Registered data from the Blood Center as well as from the Epidemiological Surveillance Nucleus (ESN) and HA were used with the purpose of collecting information about donors, type of donation and results in serologic screening tests (HBsAg, anti-HBc, anti-HCV, GTP, anti-HIV, anti-HTLV, Chagas disease and syphilis). In addition, a study was performed on the results in repetition tests that took place in the Blood Center of positive donors for hepatitis B and C markers in serologic tests as well as on their attendance at the ESN and the confirmation in the HA of the results for these markers. The population of donors was composed in its majority by men (83,6%) and individuals from 26 to 45 year-old (64,0%). Linked donations predominated (85,4%), and the greatest reasons for donation arose from solicitation and stimulus coming from family and friends. The value of prevalence in serologic screening tests was 0,63% (IC95%: 0,54 0,72) for HBsAg and 1,15% (IC95%: 1,02 1,28) for anti-HCV. The total of positive donors that should have been evaluated in the HA suffered a loss of 55,5% among the suspects of having hepatitis B and of 58,7% among the suspects of having hepatitis C, reaching a total of 266 donors lost during follow-up. The value of prevalence in confirmatory tests was 0,22% (IC95%: 0,16 0,28) for hepatitis B and 0,31% (IC95%: 0,24 0,38) for hepatitis C. The copositiveness between GPT and hepatitis markers in serologic screening tests was 8.8% for hepatitis C virus and 0.5% for hepatitis B virus, indicating that determination of this enzyme is not helpful in selection of donors in blood banks.

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Umeda, Makoto. "Hepatitis B virus infection in lymphatic tissues in inactive hepatitis B carriers". Kyoto University, 2007. http://hdl.handle.net/2433/135682.

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Arauz-Ruiz, Patricia. "Molecular epidemiology of hepatitis A and hepatitis B virus in central America /". Stockholm : Repro Print, 2002. http://diss.kib.ki.se/2002/91-7349-208-6/.

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5

Luo, Ying. "Hepatitis B virus specific immune response after liver transplantation for chronic hepatitis B /". Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B3697724X.

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Luo, Ying, e 羅英. "Hepatitis B virus: specific immune response after liver transplantation for chronic hepatitis B". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B3697724X.

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7

Kandpal, Manish. "Role of defective hepatitis B virus in wild-type hepatitis B virus replication". Thesis, IIT Delhi, 2017. http://localhost:8080/xmlui/handle/12345678/7247.

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8

Lu, Lei. "Effects of antiviral therapies on hepatitis B virus relicaptive intermediates in chronic hepatitis B". Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182359.

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Silva, Filho Hermes Pedreira da. "Estudo Molecular dos Vírus B e C das Hepatites nas Regiões Norte e Nordeste do Brasil". reponame:Repositório Institucional da FIOCRUZ, 2010. https://www.arca.fiocruz.br/handle/icict/4219.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2012-07-19T21:21:54Z No. of bitstreams: 1 Hermes Pedreira EStudo molecular dos vírus B e C...2010.pdf: 5589974 bytes, checksum: b86706272dbb22d0d349edae7d641ce1 (MD5)
Made available in DSpace on 2012-07-19T21:21:54Z (GMT). No. of bitstreams: 1 Hermes Pedreira EStudo molecular dos vírus B e C...2010.pdf: 5589974 bytes, checksum: b86706272dbb22d0d349edae7d641ce1 (MD5) Previous issue date: 2010
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
Infecções pelos vírus B e C das hepatites constituem um significante problema de saúde pública em todo mundo. Mais de 350 milhões de pessoas estão cronicamente infectadas pelo VHB e 170 milhões pelo VHC. No Brasil, a prevalência de pessoas infectadas pelo VHB varia de baixa endemicidade (<2%) até alta, (>7%), e estima-se que 1,5% da população esteja infectada pelo VHC (WHO). Estudos recentes tem demonstrado consideráveis variações entre os isolados do VHB, confirmando a diversidade de genótipos do vírus circulantes e o surgimento de mutações no genoma viral que podem ter impacto na resposta terapêutica e imune. Informações sobre a diversidade genética do VHB serão de grande valor para determinar fatores de risco associados a disseminação do vírus e auxiliar na adoção de medidas de prevenção e terapêutica. A infecção pelo VHC tornou-se um sério problema de saude pública desde que não existe uma vacina disponível e o tratamento é extremamente caro para os órgãos públicos como desgastante para o paciente. Este trabalho utilizou as ferramentas moleculares e de epidemiologia no estudo destes vírus para caracterizar molecularmente os vírus B e C das hepatites nas Regiões Norte e Nordeste, particularmente na Bahia, através de sequenciamento de DNA e análises filogenéticas. Amostras de pacientes provenientes da Bahia, Acre, Rondonia, Amazonas, Maranhão e Tocantins foram analisadas. As amostras foram oriundas de outros estudos e de centros de referência para tratamento das hepatites, sendo avaliadas 635 amostras para o VHC e 335 de VHB. Sequencias das regiões pré-S/S e pré- Core/Core do VHB e NS5b, 5UTR, E1 e Core do VHC foram utilizadas para classificação genotípica e análise filogenetica. Os genótipos mais frequentes para o VHB foram A (57%), D (10%) e F(33%) na Bahia e nas amostras da região Norte. Nós encontramos em nosso estudo 55,6% de pacientes co-infectados com VHB/Delta. Não foi possível estabelecer uma ligação genótipo específico com a evolução da infecção, e determinar a presença de mutantes relacionados à resposta terapêutica e ao escape imunológico. Com relação ao VHC, a subtipagem dos isolados foi realizada através do sequenciamento da região NS5b e 5UTR (n=230). Os sub-genótipos mais frequentes foram 1a(45,6%), 1b (46,9%), 3a (6,5%) e 2a/b(0,8%). As regiões E1 e Core também foram sequenciadas e no futuro serão utilizadas para avaliar possiveis mutações. O presente estudo mostra que a aplicação de protocolos de sequenciamento, bioinformática e filogenia são indispensáveis para a compreensão da epidemiologia molecular dos vírus das hepatites.
Infections with hepatitis B and C viruses constitute a significant public health problem worldwide. More than 350 million people are chronically infected with HBV and 170 million by HCV. In Brazil, HBV remains endemic despite widespread vaccination with prevalence of infection ranging from (<2%) low endemicity, until high (>7%) in different regions. Prevalence of HCV infection in Brazil has been estimated at 1.5%. Recent studies have shown considerable genetic variation among HBV isolates, confirming the diversity of circulating genotypes of the virus and the emergence of mutations in the viral genome that may impact on therapeutic and immune response. Information on the genetic diversity of HBV is useful for molecular epidemiology to determine risk factors associated with the spread of the virus and to inform prevention strategies and for monitoring therapy. Because there is no vaccine available to prevent HCV infection and treatment is extremely expensive for public agencies, HCV is an emerging public health problem. The treatment efficiency is directly related to viral genotype. In this study molecular epidemiology tools were used to characterize HBV and HCV in the North and Northeast, particularly in Bahia, through DNA sequencing and phylogenetic analysis. Samples from Bahia, Acre, Rondônia, Amazonas, Maranhão and Tocantins were analyzed. The samples were collected in collaboration with other studies and centers of references for hepatitis treatments. 635 samples from HCV infected patients and 335 samples from HBV infected were evaluated. Sequences of the regions pre-S / S, HBV core / pre-core, NS5B, 5UTR, HCV Core and E1 were used for genotypic classification and phylogenetic analysis. The most frequent HBV genotypes were A (57%), D (10%) and F (33%) in Bahia and in the samples from the North region. Fifty five percent of the patients from Rondônia were coinfected with HBV and HDV. In this study, we were unable to establish a connection with the particular genotype evolution of the infection and determine the presence of mutants related to therapeutic response and immune escape. In the North region co-infection with HBV genotype F and D virus is strongly associated with poor outcome of the disease as informed by the physicians and literature. Regarding HCV, the subtyping of isolates was performed by sequencing the NS5B region and 5UTR (n=230). The sub-genotypes more frequent were 1a (45.6%), 1b (46.9%), 3a (6.5%) and 2a / b (0.8%). The Core and E1 regions were also sequenced and in the future could be used to evaluate possible mutations. This study shows that the implementation of protocols for sequencing, bioinformatics and phylogenetic are essential for understanding the molecular epidemiology of hepatitis.

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駱淑芳 e Suk-fong Anna Lok. "Replication of hepatitis B virus in Chinese patients with chronic hepatitis B virus infection". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1990. http://hub.hku.hk/bib/B31981392.

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Più fonti

Libri sul tema "Hepatitis B"

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Royal Colleges of Physicians of the United Kingdom. Committee on Health Promotion. Hepatitis B (serum hepatitis). London: Faculty of Community Medicine of the Royal Colleges of Physicians of the United Kingdom, 1985.

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Freedman, Jeri. Hepatitis B. New York: Rosen, 2009.

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Branch, Canada Health Protection. Hepatitis B. [Ottawa]: Health Protection Branch, 1991.

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J, Gerety R., a cura di. Hepatitis B. Orlando: Academic Press, 1985.

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Massachusetts. Department of Public Health. Hepatitis B. Boston, MA: Massachusetts Dept. of Public Health, 1987.

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Ozaras, Resat, e Veysel Tahan, a cura di. Viral Hepatitis: Chronic Hepatitis B. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93449-5.

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Guo, Haitao, e Andrea Cuconati, a cura di. Hepatitis B Virus. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6700-1.

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Ohio. Perinatal Hepatitis B Prevention e California. Dept. of Health, a cura di. Hepatitis B & pregnancy. Columbus: Ohio Department of Health, 2002.

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Guo, Haitao, e Andrea Cuconati, a cura di. Hepatitis B Virus. New York, NY: Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-4027-2.

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Rajen, Koshy, e Caselmann Wolfgang H, a cura di. Hepatitis B virus: Molecular mechanisms in disease and novel strategies for therapy. London: Imperial College Press, 1998.

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Capitoli di libri sul tema "Hepatitis B"

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Bastug, Aliye, e Hurrem Bodur. "Acute Hepatitis B". In Viral Hepatitis: Acute Hepatitis, 25–44. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03535-8_3.

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Doucette, Karen E. "Hepatitis B". In The AST Handbook of Transplant Infections, 61–62. Oxford, UK: Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444397949.ch22.

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Korn, Klaus. "Hepatitis B". In S2k-Leitlinie - Labordiagnostik schwangerschaftsrelevanter Virusinfektionen, 21–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43481-9_5.

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Lok, Anna S. F. "Hepatitis B". In Sherlock's Diseases of the Liver and Biliary System, 395–420. Chichester, UK: John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119237662.ch21.

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Blumberg, Baruch S. "Hepatitis B". In Vaccines: A Biography, 301–15. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1108-7_17.

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Bonville, Cynthia, e Joseph Domachowske. "Hepatitis B". In Vaccines, 175–87. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58414-6_14.

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Lok, Anna S. F. "Hepatitis B". In Sherlock's Diseases of the Liver and Biliary System, 367–92. Oxford, UK: Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444341294.ch18.

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Sainburg, Robert L., Andrew L. Clark, George E. Billman, Zachary J. Schlader, Toby Mündel, Kevin Milne, Earl G. Noble et al. "Hepatitis B". In Encyclopedia of Exercise Medicine in Health and Disease, 408. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_2484.

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Dudley, Matthew Z., Daniel A. Salmon, Neal A. Halsey, Walter A. Orenstein, Rupali J. Limaye, Sean T. O’Leary e Saad B. Omer. "Hepatitis B". In The Clinician’s Vaccine Safety Resource Guide, 51–59. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94694-8_9.

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Neumann, G., H. H. Feucht, W. Becker e M. Späth. "Hepatitis B". In Gynäkologische Infektionen, 103–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-05268-2_29.

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Atti di convegni sul tema "Hepatitis B"

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Hussain, Hiba T. H., Arwa Mujahid Abdullah Al-Shuwaikh e Abbas M. Ahmed. "Hepatitis type B virus genotypes in chronic Hepatitis B patients (CHBP)". In 2ND INTERNATIONAL CONFERENCE OF MATHEMATICS, APPLIED SCIENCES, INFORMATION AND COMMUNICATION TECHNOLOGY. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0162114.

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Tomaz, Isabella Santos, GIOVANNA MATIAS DUARTE, CECILIA BRUNA DE ALMEIDA e LETICIA CRISTINA CHAVES BANDEIRA. "IMUNOPROFILAXIA: PREVENÇÃO DAS HEPATITES VIRAIS". In II Congresso Brasileiro de Imunologia On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/ii-conbrai/6034.

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Introdução: As hepatites virais constituem um desafio para a saúde pública no Brasil e no mundo. Essas doenças apresentam dados tão relevantes que a Organização Mundial da Saúde (OMS) assumiu, como um dos seus objetivos, eliminar as hepatites virais até 2030. Com isso, nos últimos 30 anos, diversos avanços científicos contribuíram para o combate dessas doenças, sendo a imunoprofilaxia, por meio das vacinas, uma das principais vertentes desenvolvidas. Objetivos: Realizar uma revisão de literatura sobre a imunoprofilaxia das hepatites virais, evidenciando sua importância para o controle e a prevenção da morbimortalidade dessas doenças. Metodologia: Foi produzida uma revisão de literatura a partir do estudo de 10 publicações científicas publicadas entre 2016 e 2020. Dos quais, foram selecionados 5(cinco), que estão presentes na base de dados PubMed e Scielo, e foi utilizado como termos de pesquisa: “Hepatitis B”, “Vaccines” e “Hepatitis A”, terminologias de acordo com o sistema de Descritores em Ciências da Saúde (DeCs). Resultados: Em relação à vacina da hepatite A, no Brasil, após sua aplicação universal, apresentaram-se estudos que evidenciaram uma queda da incidência de notificações da hepatite A. Esses estudos demonstram que após 1 mês da primeira dose, > 97% das crianças e > 95% dos adultos desenvolvem níveis protetores de anticorpos, comprovando a eficácia da vacina. No que concerne à hepatite B, a vacinação constitui o método mais eficaz para prevenir a transmissão do vírus da hepatite B (HBV) e a progressão da doença aguda e crônica. Essa imunoprofilaxia ocorre, visto que a vacina induz a produção de anti-HBs em títulos maiores ou iguais a 10 mUI/ml, sendo assim uma vacina imunogênica e protetora por induzir a formação de anticorpos contra o antígeno de superfície da hepatite B. Essa vacina também confere proteção contra o vírus da hepatite D (HDV), já que só ocorre infecção pelo HDV em pessoas previamente infectadas pelo HBV. Conclusão: Dessa forma, as hepatites virais são um problema de saúde pública mundial que devem ser combatidas para erradicá-las. Visando esse combate, é necessário buscar a discussão e a aplicação efetiva da imunoprofilaxia como uma principais das medidas a serem usadas contra essas doenças.

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Ekmen, Onder. "A Case of Fulminant Hepatitis B Reactivation After Hepatitis C Treatment in Hepatitis B+C Co-infection". In 39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0042-1760078.

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Baraka, Fatiha, Chahrazed Kandouci, Fadela Meflah, Menaouar Rehni e Baderdine Abdelkrim Kandouci. "P086 Hepatitis B and vaccination". In Occupational Health: Think Globally, Act Locally, EPICOH 2016, September 4–7, 2016, Barcelona, Spain. BMJ Publishing Group Ltd, 2016. http://dx.doi.org/10.1136/oemed-2016-103951.407.

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Zamorshchikova, Olga, Snezhana Sleptsova, Keskilene Petrova, Maria Savvina e Spiridon Sleptsov. "Occult Hepatitis B: Case History". In Conference on Health and Wellbeing in Modern Society (CHW 2021). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/ahsr.k.220103.051.

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Lim, Chee Hooi, e Rajneesh Kumar. "P82 Hepatitis B reactivation in patients with previous hepatitis B exposure; don’t jump, wait". In Abstracts of the BSG Annual Meeting, 20–23 June 2022. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2022. http://dx.doi.org/10.1136/gutjnl-2022-bsg.139.

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Kipiani, E., M. Butsashvili, G. Kamkamidze e G. Abashidze. "STUDY OF RISK FACTORS AFFECTING HBV VACCINE EFFICIENCY AMONG CHILDREN IN GEORGIA". In International Trends in Science and Technology. RS Global Sp. z O.O., 2020. http://dx.doi.org/10.31435/rsglobal_conf/30122020/7346.

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Abstract (sommario):

In the conditions of mass vaccination of hepatitis B, all over the world, including in Georgia, in the vaccinated population, the numberof those individuals who could not develop Anti-HBs are growing every day. According to the literature, the main reason for the ineffective vaccination of hepatitis B is considered to be an increase in the prevalence of express mutants among the hepatitisB virus population, which is of a similar intensity throughout the world. In parallel with a detailed analysis of literature sources, the scientific article for the first time studied the seroprevalence of Anti-HBs in the population of Georgian vaccinatedchildren.

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Hattori, M., Y. Ito, S. Takahashi, I. Fukada, T. Iwase, H. Iwata e K. Hatake. "Abstract P5-13-12: Risk of hepatitis B virus (HBV) reactivation in hepatitis B surface antigen negative/ hepatitis B core antibody positive and/or hepatitis B surface antibody positive breast cancer patients who receive chemotherapy". In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p5-13-12.

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Side, Syafruddin, Irwan, Usman Mulbar e Wahidah Sanusi. "SEIR model simulation for Hepatitis B". In 3rd Electronic And Green Materials International Conference 2017 (EGM 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.5002379.

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Side, Syafruddin, Irwan, Usman Mulbar e Wahidah Sanusi. "SEIR model simulation for Hepatitis B". In 3RD ELECTRONIC AND GREEN MATERIALS INTERNATIONAL CONFERENCE 2017 (EGM 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.5002392.

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Rapporti di organizzazioni sul tema "Hepatitis B"

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Hyams, Kenneth C., Mohamed A. Al-Arabi, Ahmed A. Al-Tagani, James F. Messiter, Abdella A. Al-Gaali e John F. George. Epidemiology of Hepatitis B in the Gezira Region of Sudan. Fort Belvoir, VA: Defense Technical Information Center, gennaio 1989. http://dx.doi.org/10.21236/ada239688.

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Oster, Emily, e Gang Chen. Hepatitis B Does Not Explain Male-Biased Sex Ratios in China. Cambridge, MA: National Bureau of Economic Research, maggio 2008. http://dx.doi.org/10.3386/w13971.

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Nguyen, Tung, Mandana Khalili, Janice Tsoh, Judith Walsh, Elizabeth Goldman, Arcadi Kolchak, Ginny Gildengorin, Ching Wong e Ivy Lau. Comparing Ways to Increase Hepatitis B and C Screening Among Asian Americans. Patient-Centered Outcomes Research Institute® (PCORI), marzo 2020. http://dx.doi.org/10.25302/02.2020.ad.12114615.

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Ma, Grace X., Yin Tan, Lin Zhu, Min Qi Wang, Shumenghui Zhai, Jing Yu, Brenda Seals et al. Testing a Program to Help Monitor Chronic Hepatitis B among Asian-American Patients. Patient-Centered Outcomes Research Institute (PCORI), ottobre 2020. http://dx.doi.org/10.25302/10.2020.ad.140312613.

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Xie, lu, guangwei Liu, pengyu Li, yanan Liu, xinyi He, ruibo Huan e huijun Guo. Analysis of risk factors of chronic hepatitis B patients with Viremia: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, luglio 2023. http://dx.doi.org/10.37766/inplasy2023.7.0107.

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Ma, Yingying. Meta-analysis of the therapeutic effect of Entecavir combined with milk thistle on hepatitis B. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, settembre 2023. http://dx.doi.org/10.37766/inplasy2023.9.0043.

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Goller, Jane, Stephanie Munari, Cassandra Caddy, Teralynn Ludwick, Jacqueline Coombe, Meredith Temple-Smith, Lena Sanci e Jane Hocking. General Practice engagement: STI, HIV and viral hepatitis care. The Sax Institute, giugno 2023. http://dx.doi.org/10.57022/lnur4773.

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Early detection and treatment of sexually transmitted infections, HIV, and hepatitis B and C are vital to minimise the harm they cause. This Evidence Check aimed to identify effective initiatives that engage and support GPs and the GP clinic workforce in NSW to increase testing for these conditions. It also aimed to identify effective modifications to practice management software to increase GP engagement in screening and care for these conditions. Sixty-two articles were found in total. The most effective initiatives used multiple interventions, particularly provider education and quality improvement. They involved both GPs and other health workers, and offered clinic-level initiatives to help identify patients at higher risk (e.g. software-generated alerts) and engage them in testing (e.g. through self-collected specimens). Models of care that used nurse-led testing or links to specialist services offered a way to increase capacity to carry out testing. The quality of evidence was mixed—there were few randomised controlled trials, and little evidence about the sustainability of the initiatives over time, highlighting the need for further high-quality research.

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Zeng, Hua, e Yuanliang Liu. Entecavir in the treatment of chronic hepatitis B in children and adolescents:Systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, maggio 2020. http://dx.doi.org/10.37766/inplasy2020.5.0112.

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Kancheva, Lyudmila, Petar Nikolov, Tsvetelina Velikova, Ivan Valkov, Rossen Nikolov e Lyudmila Mateva. Soluble CD14 is Associated with Disease Activity and Severity in Chronic Viral Hepatitis C and B. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, giugno 2018. http://dx.doi.org/10.7546/crabs.2018.06.17.

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Zhang, JunLI, HongYuan Mou, Ying He e XiaoYu Hu. Fuzheng Huayu Combined with Tenofovir Disoproxil Fumarate for Hepatitis B: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, novembre 2021. http://dx.doi.org/10.37766/inplasy2021.11.0002.

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