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De Wolff, L., S. Arends, E. Mossel, G. S. Van Zuiden, J. F. Van Nimwegen, L. Olie, A. J. Stel et al. "POS0754 PATIENT ACCEPTABLE SYMPTOM STATE (PASS) IN PATIENTS WITH PRIMARY SJÖGREN’S SYNDROME IN DAILY CLINICAL PRACTICE". Annals of the Rheumatic Diseases 81, Suppl 1 (23 maggio 2022): 663.1–663. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2854.
Testo completoAbstract (sommario):
BackgroundPrimary Sjögren’s syndrome (pSS) has great impact on all aspects of patients’ lives, not only physically, but also mentally, socially and financially.1 Sicca symptoms are mainly treated with local treatment, but no systemic immunosuppressive treatment is registered yet for pSS, which may have significant consequences on whether patients find their symptom state acceptable (PASS). In a previous study, a cut-off for acceptable symptom state based on the EULAR Sjögren’s Syndrome Patient Reported Index (ESSPRI, score <5) was developed for inclusion of patients with an unacceptable symptom state in clinical trials.2ObjectivesTo explore the presence of PASS in a standard of care cohort of pSS patients and to compare patient characteristics and disease activity including ESSPRI between patients with and without PASS.MethodsConsecutive outpatients with pSS from the REgistry of Sjögren Syndrome LongiTudinal (RESULT) cohort, who fulfilled the ACR/EULAR classification criteria and had available PASS data at baseline were included. Patient-reported outcomes were reported through questionnaires, which included the PASS (“Considering all the different ways your disease is affecting you, if you were to stay in this state for the next few months, do you consider your current state satisfactory?”; yes/no) and ESSPRI (“How severe has your dryness, fatigue and pain been during the last two weeks?”; scale 0-10). An acceptable ESSPRI symptom state has been defined as <5.2 Systemic disease activity was assessed with EULAR Sjögren’s Syndrome Disease Activity Index (ESSDAI). Independent samples t-test, Mann-Whitney U test or Chi Square test were used to analyse differences between patients with or without PASS.ResultsOf 277 included pSS patients, 248 (90%) were female, median age was 54 years (IQR 43-64) and disease duration 5 years (2-11). 198 (71%) patients scored their symptom state as acceptable according to PASS. Patients with PASS were significantly older and had a longer disease duration compared to patients without PASS. Furthermore, patients with PASS had more often a low disease activity according to ESSDAI, and less often moderate disease activity (Table 1). The difference in ESSDAI activity was mainly observed in the articular and constitutional domains. ESSPRI was significantly lower in patients with PASS (median 5 vs. 7). No differences were seen in functional or laboratory parameters (Table 1). Of all included patients, only 86 (31%) patients had an acceptable symptom state according to the pre-defined cut-off point for ESSPRI (score <5). Sensitivity and specificity of this ESSPRI cut-off point for reaching PASS was 40% and 92%, respectively.Table 1.Baseline characteristics of pSS patients with and without PASSPASS (n=198)Without PASS (n=79)Gender (female)177 (89)71 (90)Age (years)57 (44-65)*49 (41-60)*Disease duration (years)6 (2-12)*5 (2-8)*ESSDAI (total)4 (2-6) (n=191)4 (2-9) (n=75)<5127 (66)*38 (51)*5-1452 (27)*32 (43)*≥1412 (6)5 (7)ESSPRI (total)5 (4-7)**7 (6-8)**<580 (40)**6 (8)**Schirmer’s test (mm)4 (1-10) (n=179)4 (1-10) (n=72)Ocular staining score2 (1-4) (n=190)2 (0-4) (n=77)Unstimulated whole salivary flow (ml/min)0.05 (0.01-0.14) (n=187)0.08 (0.01-0.19) (n=76)Stimulated whole salivary flow (ml/min)0.54 (0.15-0.99) (n=189)0.58 (0.21-0.97) (n=76)SSA positive172/197 (87)66/79 (84)IgG (g/L)14 (11-19) (n=196)14 (10-19) (n=79)Rheumatoid factor (IU/ml)12 (3-39) (n=196)16 (2-47) (n=78)Data presented as median (IQR) or n (%)*Significant difference p<0.05***Significant difference p<0.001ConclusionThe majority (71%) of pSS patients reported being in an acceptable symptom state according to the PASS question in our standard of care cohort in daily clinical practice, despite high ESSPRI scores (60% with score ≥5). Further analyses of influences of treatment in these patients will be conducted.References[1]Vieira et al. Clin Exp Rheum 2021;39(Suppl. 133):S14-S16.[2]Seror et al. Ann Rheum Dis 2016;75:382-389.AcknowledgementsUnrestricted grants from the Dutch Arthritis Patients Association (ReumaNL), Bristol-Myers Squibb and NovartisDisclosure of InterestsLiseth de Wolff: None declared, Suzanne Arends: None declared, Esther Mossel: None declared, Greetje S. van Zuiden: None declared, Jolien F. van Nimwegen Speakers bureau: Bristol-Myers Squibb, Consultant of: Bristol-Myers Squibb, Lisette Olie: None declared, Alja J. Stel: None declared, Konstantina Delli: None declared, Gwenny M. Verstappen: None declared, Frans G.M. Kroese: None declared, Arjan Vissink: None declared, Hendrika Bootsma Speakers bureau: Bristol Myers Squibb and Novartis, Consultant of: Bristol Myers Squibb, Roche, Novartis, Medimmune, Union Chimique Belge, Grant/research support from: Unrestricted grants from Bristol Myers Squibb and Roche
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Moffit, Dani M., Jamie L. Mansell e Anne C. Russ. "An Educational Relationship Between an Athletic Training Program and an Elementary School". Kinesiology Review 6, n. 4 (novembre 2017): 380–83. http://dx.doi.org/10.1123/kr.2017-0039.
Testo completoAbstract (sommario):
Temple University Owls Athletic Training Society (OATS), committed to education and community involvement, formed a relationship with Lanning Square Elementary School (LSE). Located less than 10 miles from campus in Camden, NJ, a high incidence of poverty, violence, and one-parent families is the norm. Through a grant, OATS adopted the fifth-grade classes at LSE for 1 year, beginning with letter exchanges between OATS students and elementary students. OATS traveled to LSE for their holiday party, met their pen pals, and provided healthy snacks. In the spring, the LSE completed a health/wellness unit and visited Temple. Students shared several health activities including learning about bones/muscles in the anatomy laboratory, stretching properly, and exercising. They received lunch and Temple mementos. OATS raised money the following year to continue the project. This allowed OATS and administrators to participate positively in our community, promote diversity, and introduce healthy lifestyles to youngsters.
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Bwambale, Asanairi, Tom Mulegi e Samanya Bulhan. "The Effect of Laissez-Faire Leadership Style on Academic Performance of Primary School Pupils in Selected Primary Schools in Kasese District". IAA JOURNAL OF EDUCATION 10, n. 1 (23 febbraio 2024): 23–28. http://dx.doi.org/10.59298/iaaje/2024/10123.28.
Testo completoAbstract (sommario):
Education plays a crucial role in the development of society, particularly in the developing world. The purpose of this research is to assess the impact of a laissez-faire leadership style on the academic performance of primary school students in selected schools within Kasese district. The study utilized a cross-sectional survey design, employing both quantitative and qualitative methodologies. Quantitative data was processed by coding and entering it into a computer program called the Statistical Package for Social Sciences (SPSS 22.0). This data was then summarized using frequency tables, allowing for the identification of errors and necessary revisions. Among the respondents, 27 (45%) disagreed with the statement, indicating that teachers appreciate the leadership style that grants them freedom. This lack of accountability can have negative consequences. Conversely, 24 (40%) agreed that head teachers adopt a hands-off approach, empowering teachers to independently solve problems, while 60% disagreed with this statement. Additionally, 17 (28.3%) of head teachers spend the majority of their time outside the school, with their presence on campus being rather casual. This evidence suggests that head teachers do not perceive their presence as significant, failing to recognize its positive impact on academic performance. In Kasese District, the Primary Leaving Examination (PLE) results for 2018 and 2020 revealed a disappointing pass rate of only 47%. Therefore, it is crucial to examine various factors, such as the leadership styles of head teachers, in order to address this issue effectively. Keywords: laissez-faire leadership, academic performance, primaryschool, pupils, social studies.
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Akbar, Amar, e Tiraporn Junda. "The Experience of Doctoral Nursing Candidate in Writing Publication in Journal". NurseLine Journal 5, n. 2 (4 febbraio 2021): 241. http://dx.doi.org/10.19184/nlj.v5i2.15788.
Testo completoAbstract (sommario):
Graduates of PhD nursing programs are expected to produce complex genres of writing such as abstracts, research grants, manuscripts for publication, and dissertations. Research evidence shows a wide range of variability in writing among doctoral nursing students, and these variations may become more profound when exposed to complex genres. the objective of this study to explore the experience of PhD candidate in writing publication in high indexed journal. This case study used depth interview, semi structured question, Interview conducting in English, recorded voice used for transcribing data in 2 respondents from doctoral nursing candidate in Bangkok Thailand comes from Mahidol university and Chulalongkorn university. Participants’ criteria for this study are: 1) Doctoral candidate with minimum 1 publication in high indexed journal (Scopus/ ISI Thompson) 2) Doctoral nursing students that study in Thailand 3) Pass Qualifying Exam. Data analysis used modification Benner’s methods use in this study. This study exposing three themes. Theme 1: Strategies for publish. Theme 2: Support for publishing journal. Theme 3: two ways Communication with journal editors and public. Introduce scholarly writing at the undergraduate level and reinforce across the nursing education continuum, provide students with examples of quality scholarly writing, encourage student to connect with writing mentors (peers, colleagues, family, editor, faculty) are main recommendation for postgraduate student for increasing high level publication of nursing students.
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Rodriguez, F., D. Buitrago-Garcia, G. Sánchez e P. Santos-Moreno. "POS1491-HPR THE USEFULNESS OF THE PATIENT ACTIVITY SCORE-PASS-II TO ASSESS DISEASE ACTIVITY DURING THE COVID-19 LOCKDOWN IN PATIENTS WITH RHEUMATOID ARTHRITIS". Annals of the Rheumatic Diseases 81, Suppl 1 (23 maggio 2022): 1091.1–1091. http://dx.doi.org/10.1136/annrheumdis-2022-eular.5108.
Testo completoAbstract (sommario):
BackgroundMany measurement tools are designed to assess disease activity for Rheumatoid Arthritis (RA) patients. One of the most used tools is the Disease Activity Score- DAS28 which assesses the number of painful joints, erythrocyte sedimentation, and a patient’s global assessment. The assessment is performed by a clinician and requires laboratory exams. Unfortunately, from March to August 2019, Colombia had one of the strictest responses to the COVID-19 pandemic according to the COVID-19 stringency Index(1). One of the main restrictions was the preventive isolation of older populations, especially those with comorbidities. These restrictions challenged the rheumatology practice because face-to-face consultations were not possible. Due to the above, measurements like the PAS-II score should be used to assess disease activity during the pandemic.ObjectivesTo describe disease activity according to the Patient Activity Score- PAS-II score patients with RA and compare its results to the most recent DAS28 assessment before the COVID-19 pandemic.MethodsWe conducted a descriptive study; patients were followed during the COVID-19- lockdown in a video consultation. The PAS-II score was applied to assess disease activity as an alternative to the DAS28 assessment. The patients were part of an educational program, clinical charts were reviewed to collect the study variables. We collected demographic data and DAS28 before the pandemic started. We present a descriptive analysis of DAS28 severity and the results obtained by the PASS-II score.ResultsThe educational program enrolled 250 participants; 196 patients had complete data. 93% of participants were women, mean age was 64 years IQR (54-67). 43% of participants were married or had a civil union, 26% were single, 20% divorced, and 11% were widowed. Regarding educational level, 25% had finished elementary school and 39% high school; the remaining 36% had higher education. When we compared the last DAS28 assessed by a rheumatologist between January, and March 2019, 67% of patients were in remission, while in July 2019, the PASS-II score reported that 7% of patients were in remission and 75% had low or minimal activity. Figure 1- Table 1.Figure 1.Table 1.DISEASE ACTIVITIYDAS28PASS-IIRemission67%6%Low (Minimal)14%75%Moderate15%18.5%High/Severe4%0.5%ConclusionThe PASS score is a helpful tool to assess disease activity in patients with RA, especially in situations where the patient cannot see a rheumatologist in a face-to-face consultation; however, patients in severe disease activity should not delay the consultation with a clinician. As other studies have demonstrated, patient-reported outcome measures should be adopted in clinical practice as an alternative for treat- to- targe strategies(2). Further studies should be conducted to assess the impact of the pandemic in countries with high levels of restrictions in the course of RA.References[1]Hale T, Angrist N, Goldszmidt R, Kira B, Petherick A, Phillips T, et al. A global panel database of pandemic policies (Oxford COVID-19 Government Response Tracker). Nature Human Behaviour. 2021;5(4):529-38.[2]Salaffi F, Di Carlo M, Farah S, Marotto D, Atzeni F, Sarzi-Puttini P. Rheumatoid Arthritis disease activity assessment in routine care: performance of the most widely used composite disease activity indices and patient-reported outcome measures: Comparison of disease activity indices in RA. Acta Biomedica Atenei Parmensis. 2021;92(4):e2021238.AcknowledgementsThis project was funded by the Ministry of Science, Technology and Innovation MINCIENCIAS. Grant number: 695180763684Disclosure of InterestsFernando Rodriguez: None declared, Diana Buitrago-Garcia: None declared, GUILLERMO SÁNCHEZ: None declared, Pedro Santos-Moreno Speakers bureau: Pfizer, Janssen, Abbvie, Biopas-UCB, Bristol, Roche, Novartis, Lilly, Consultant of: Pfizer, Janssen, Abbvie, Biopas-UCB, Bristol, Roche, Novartis, Lilly, Grant/research support from: Pfizer, Janssen, Abbvie, Biopas-UCB, Bristol, Roche, Novartis, Lilly
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Hoechstetter, Manuela, Philipp Eissmann, Nike Hucke, Anna van Troostenburg, Heribert Ramroth e Wolfgang Knauf. "Results from a Prospective Real World Study Show Strong Efficacy of Idelalisib in CLL, Including High-Risk CLL, and Provide Evidence That Pjp Prophylaxis Positively Impacts on Overall Survival". Blood 132, Supplement 1 (29 novembre 2018): 4428. http://dx.doi.org/10.1182/blood-2018-99-112843.
Testo completoAbstract (sommario):
Abstract Introduction: Idelalisib is a first-in-class PI3Kδ-inhibitor. In clinical studies idelalisib demonstrated significant efficacy in patients with CLL, including patients with TP53 aberrations (del17p and/or TP53m). On this basis national and international guidelines in Europe recommend idelalisib as one treatment option in this high-risk CLL patient population. However, it is unclear how efficacy reported in clinical studies translates into real world experience. Considering the importance of such data, we initiated a real world study soon after market authorization of idelalisib in the European Union prospectively investigating efficacy and safety of idelalisib in routine clinical practice. Concomitant PJP prophylaxis is a risk minimization measure that was introduced after market authorization of idelalisib. Nevertheless, the impact on patient outcomes in routine clinical practice has not been studied in detail. We therefore also analyzed the impact of PJP prophylaxis on overall survival (OS) within this real world cohort. Methods: A prospective, two-cohort, multicenter, non-interventional post-authorization safety study (PASS) reporting real world safety and efficacy data on the use of idelalisib in Germany. Inclusion of patients was based on the physician's decision to initiate treatment with idelalisib in accordance with the European Summary of Product Characteristics. Descriptive statistics were used for data analysis. Results: This analysis included 84 CLL patients with a median age of 74 years. 88% of patients were older than 65 years, 70% were male and 86% presented with one or more co-morbidities. Binet stage A, B, C was reported in 25%, 33% and 37% of patients, respectively. The median time from diagnosis to start of idelalisib therapy was 89.5 months and patients received a median number of two prior lines of therapy, including treatment with the BTK inhibitor ibrutinib in 11 patients (13%). With a median observation time of 11.5 months the median overall survival (OS) for the entire CLL patient population was not reached. Our CLL cohort included 24 patients (29%) that did not receive PJP prophylaxis for idelalisib therapy. We therefore compared OS in patients with and without concomitant PJP prophylaxis. In patients receiving PJP prophylaxis survival rates were higher in the first 6-12 months of therapy, with 6-month and 12-month survival rates in patients with vs without PJP prophylaxis of 98% vs 76% and 84% vs 76%, respectively (Figure 1). 19% of CLL patients (n=16) had documented TP53 aberrations, including five patients that received idelalisib as first-line treatment. In patients with TP53 aberrations the overall response rate (ORR) was 77% compared to 67% in patients without TP53 aberrations. Importantly, the 12-month survival rates for patients with and without TP53 aberrations were similar with 81% and 83%, respectively. Median OS was not reached for either patient population (Figure 2). Conclusion: This prospective real world study started collecting data on the efficacy and safety of idelalisib in routine clinical practice soon after market authorization of idelalisib in Europe. Results demonstrate similar efficacy of idelalisib irrespective of the patients' TP53 status confirming the efficacy previously reported in pivotal clinical studies. Additionally, our results provide evidence that PJP prophylaxis is an effective risk minimization measure impacting on survival. Disclosures Hoechstetter: Hexal: Other: Travel Grants; Abbvie: Other: Travel Grants; Gilead Sciences: Consultancy, Other: Travel Grants. Eissmann:Gilead Sciences: Employment. Hucke:Gilead Sciences: Employment. van Troostenburg:Gilead Sciences: Employment. Ramroth:Gilead Sciences: Employment. Knauf:Celgene: Consultancy, Honoraria; Gilead Sciences: Consultancy; Janssen: Consultancy; Mundipharma: Consultancy; Roche: Consultancy; Amgen: Consultancy, Honoraria; AbbVie: Consultancy.
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Vasiliu, Octavian. "S196. TRANSCRANIAL MAGNETIC STIMULATION IN SCHIZOPHRENIA WITH PROMINENT NEGATIVE SYMPTOMS- A REVIEW OF THE LITERATURE". Schizophrenia Bulletin 46, Supplement_1 (aprile 2020): S113. http://dx.doi.org/10.1093/schbul/sbaa031.262.
Testo completoAbstract (sommario):
Abstract Background Negative symptoms in schizophrenia are associated with lower quality of life, worse functional prognosis and poorer response to the psychopharmacological treatment [1]. Many efforts have been made to find new approaches for negative symptoms, and neuromodulation techniques may represent a solution for these patients when antipsychotics have reached their limits of efficacy [2]. Transcranial magnetic stimulation (TMS) is based on the use of alternating magnetic fields to induce electrical current in the cortical areas, being mainly used for patients with treatment-resistant depression and it is considered safe and well tolerated [3]. Methods A narrative review of data regarding the efficacy of transcranial magnetic stimulation for patients with schizophrenia with prominent negative symptoms was performed. Papers published between January 2000 and July 2019 in the main electronic databases (PubMed, Cochrane, EMBASE, CINAHL) were included in this review. The keywords used for database search were “schizophrenia” and “negative symptoms” and “transcranial magnetic stimulation” or “repetitive transcranial magnetic stimulation”. Results The treatment of negative symptoms in schizophrenia with high frequency TMS has been associated with favorable results in clinical trials. The targeted zones were dorsolateral prefrontal cortex, either bilaterally or only on the left side. The results varied upon the stimulation regimen, including duration, frequency, uni- versus bilaterally application etc. Two meta-analyses were identified and their results supported an effect size from 0.58 to 0.63 [2,3]. However, negative results derived from well designed clinical trials exist, which show no difference in the Positive and Negative Syndromes Scale (PANSS) - negative symptom score between rTMS and sham rTMS [4,5]. An exploratory analysis of a large-scale trial showed the impact of rTMS on different negative symptom domains confirmed no additional beneficial effect of the actove comparative to sham rTMS [5]. Also, data exist about the potential of rTMS for increasing task-related in frontal areas in patients with schizophrenia with negative predominant symptoms, which may grant further exploration of the mechanisms underlying the effects of rTMS. Discussion Data about the efficacy of TMS in schizophrenia with negative symptoms are controversial, because both evidence to support its efficacy and its lack of efficacy exist in clinical trials. However, meta-analyses support an important size effect which may be comparable to that of the pharmacological treatment. References
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Ortolan, A., S. Ramiro, F. A. Van Gaalen, T. K. Kvien, R. B. M. Landewé, P. M. Machado, A. Ruyssen-Witrand, A. Van Tubergen, C. Bastiaenen e D. Van der Heijde. "OP0008 DEVELOPMENT AND VALIDATION OF AN ALTERNATIVE ANKYLOSING SPONDYLITIS DISEASE ACTIVITY SCORE WHEN PATIENT GLOBAL ASSESSMENT IS UNAVAILABLE". Annals of the Rheumatic Diseases 79, Suppl 1 (giugno 2020): 6. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1122.
Testo completoAbstract (sommario):
Background:Ankylosing Spondylitis Disease Activity Score (ASDAS) is a composite index measuring disease activity in axial spondyloarthritis (axSpA). It includes questions from the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Patient Global Assessment (PGA), and inflammation biomarkers. However, ASDAS calculation is not always possible because PGA is sometimes not collected.Objectives:To develop an alternative ASDAS to be used in research settings when PGA is unavailable.Methods:Longitudinal data from 4 axSpA cohorts and 2 RCTs were combined. Observations were randomly split in a development (N=1026) and a validation cohort (N=1059). Substitutes of PGA by BASDAI total score, single or combined individual BASDAI questions, and a constant value, were considered. In the development cohort, conversion factors for each substitute were defined by Generalized Estimating Equations. Validation was performed in the validation cohort according to the OMERACT filter, taking into consideration: 1) Truth (agreement with original-ASDAS in the continuous score, by intraclass correlation coefficient -ICC- and in disease activity states, by weighted kappa) 2) Discrimination (standardized mean difference –SMD- of ASDAS scores between high/low disease activity states defined by external anchors e.g Patient Acceptable Symptom State –PASS-; agreement -kappa- in the % of patients reaching ASDAS improvement criteria according to alternative vs. original formulae) 3) Feasibility.Results:Taking all psychometric properties into account and comparing the different formulae (Table), alternative-ASDAS using BASDAI total as PGA replacement proved to be: 1) truthful (agreement with original-ASDAS: ICC=0.98, kappa=0.90); 2) discriminative: it could discriminate between high/low disease activity states (e.g. scores between PASS no/yes: SMD=1.37 versus original-ASDAS SMD=1.43) and was sensitive to change (agreement with original-ASDAS in major improvement/clinically important improvement criteria: kappa=0.93/0.88; 3) feasible (BASDAI total often available; conversion coefficient≈1).Table.Psychometric properties of alternative ASDAS formulaeConclusion:Alternative-ASDAS using BASDAI total score as PGA replacement is the most truthful, discriminative and feasible instrument. This index enables ASDAS calculation in existing cohorts without PGA.Disclosure of Interests:Augusta Ortolan: None declared, Sofia Ramiro: None declared, Floris A. van Gaalen: None declared, Tore K. Kvien Grant/research support from: Received grants from Abbvie, Hospira/Pfizer, MSD and Roche (not relevant for this abstract)., Consultant of: Have received personal fees from Abbvie, Biogen, BMS, Celltrion, Eli Lily, Hospira/Pfizer, MSD, Novartis, Orion Pharma, Roche, Sandoz, UCB, Sanofi and Mylan (not relevant for this abstract)., Paid instructor for: Have received personal fees from Abbvie, Biogen, BMS, Celltrion, Eli Lily, Hospira/Pfizer, MSD, Novartis, Orion Pharma, Roche, Sandoz, UCB, Sanofi and Mylan (not relevant for this abstract)., Speakers bureau: Have received personal fees from Abbvie, Biogen, BMS, Celltrion, Eli Lily, Hospira/Pfizer, MSD, Novartis, Orion Pharma, Roche, Sandoz, UCB, Sanofi and Mylan (not relevant for this abstract)., Robert B.M. Landewé Consultant of: AbbVie; AstraZeneca; Bristol-Myers Squibb; Eli Lilly & Co.; Galapagos NV; Novartis; Pfizer; UCB Pharma, Pedro M Machado Consultant of: PMM: Abbvie, Celgene, Janssen, Lilly, MSD, Novartis, Pfizer, Roche and UCB, Speakers bureau: PMM: Abbvie, BMS, Lilly, MSD, Novartis, Pfizer, Roche and UCB, Adeline Ruyssen-Witrand Grant/research support from: Abbvie, Pfizer, Consultant of: Abbvie, BMS, Lilly, Mylan, Novartis, Pfizer, Sandoz, Sanofi-Genzyme, Astrid van Tubergen Consultant of: Novartis, Caroline Bastiaenen: None declared, Désirée van der Heijde Consultant of: AbbVie, Amgen, Astellas, AstraZeneca, BMS, Boehringer Ingelheim, Celgene, Cyxone, Daiichi, Eisai, Eli-Lilly, Galapagos, Gilead Sciences, Inc., Glaxo-Smith-Kline, Janssen, Merck, Novartis, Pfizer, Regeneron, Roche, Sanofi, Takeda, UCB Pharma; Director of Imaging Rheumatology BV
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Marques, A., C. Matos, P. Livermore, E. Nikiphorou e R. J. O. Ferreira. "POS0791-HPR NURSE EDUCATION ON METHOTREXATE FOR PEOPLE WITH RHEUMATIC AND MUSCULOSKELETAL DISEASES: A SCOPING REVIEW TO INFORM EDUCATIONAL STANDARDS". Annals of the Rheumatic Diseases 82, Suppl 1 (30 maggio 2023): 688–89. http://dx.doi.org/10.1136/annrheumdis-2023-eular.5588.
Testo completoAbstract (sommario):
BackgroundPatient education (PE) is a key role of nurses,[1] which includes providing information, training, and support about methotrexate (MTX), an anchor drug in rheumatology. However, there is wide variation in the access to rheumatology nurse consultations in Europe and no standard strategy about when, what, and how nurses should provide PE to these patients.ObjectivesThe objective of this scoping review was to provide a comprehensive overview of the existing research on nurse education on MTX for children/youth and adults with Rheumatic and musculoskeletal diseases (RMDs).MethodsWe searched PubMed (MEDLINE), Scopus and Cochrane Database, and CINAHL complete, from inception until march of 2022. Articles on patient education with a focus on MTX exclusively were included. Two independent reviewers performed standardized data extraction and synthesis.ResultsFrom 292 references identified, 14 fulfilled the inclusion criteria (Figure 1). A Summary of study methods and results are presented in Table 1.Table 1.Characteristics of included studies1st Author (year), CountryStudy designStudy sampleaResultsBurma (1996), EUANon-randomised experimental183Addition of a supplemental “MTX pocketcard” improve knowledge on MTXHomer (2009), UKRCT62Better adherence and satisfaction to MTX after nursing counsellingLivermore (2003), UKNon-randomised experimental18 familiesTeaching families to manage MTX administration at home is feasibleSowden (2012), UKCross-sectional51Despite consistent baseline patient education, end-user knowledge and awareness pertinent to MTX safety are limitedBarton (2013), EUACohort135Age > 55, less than high school education, better function, and biologic use were independently associated with poor knowledge on MTXCiciriello (2014), AustraliaCohort31Multimedia patient education program about MTX treatment for RA found to be user-friendly and easily implementable. A validated scale to evaluate MTX-related knowledge was developed.Katz (2015), CanadaRCT29An education video may be a good supplement to standard in-person nurse education for MTX self-injectionRittberg (2016), CanadaCross-sectional60 youtube videos(adults, nurses)Videos may be a useful additional educational toolRobinson (2017), UKCross-sectional104 nursesNurses’ confidence correlated with knowledge about MTX and time in the role of the nurses. The amount of training received correlated with confidence but not with knowledge.Robinson (2018), UKQualitative6 rheumatology nursesNurses described a lack of confidence when they first started counselling patients commencing MTX, with a wide variation in training.Sørensen (2020), NorwayQualitative8 children11 parents7 nursesWhen clinicians used an acknowledge communication and offered sufficient coping strategies, children seemed to become involved in the procedure and acted with confidence. The initial educational training session may have a great impact on long-term outcomes.Otón (2021), SpainQualitative12 adult representativesBarriers and facilitators of adherence to MTX involve: drug-related aspects, patient- physician relationship, social environment, and medication and medical care practicalities.Robinson (2021), UKMixed-methods10 consultations (adults, nurses)Consultations generally consisted of communication from nurse to patient rather than a dialogue, with an ‘overloading’ of the patient with information.Fayet (2021), FranceRetrospective66A therapeutic education session improves patients’ knowledge about MTX.a. Adult patients unless stated otherwiseConclusionThrough this scoping review, we identify that knowledge of MTX improves when education by nurses is provided. Patient education about MTX can be de delivered in different forms and can result in better satisfaction and adherence. More RCTs with powered samples are required.Reference[1]Bech B, et al. Annals Rheum Diseases 2020;79:61-68.AcknowledgementsThis study was funded by an unrestricted grant from medac, without any involvement in the scientific work.We thank the members of the RECONNECT-MTX group: Ágnes Ágoston-Szabó, Ana Isabel Rodriguez Vargas, Ana Pais, Ane Ludvigsen, Angela Camon, Claudia Paiva, Darja Batšinskaja, Ellen Moholt, Jana Melicharová, Karlien Claes, Khadija El Aoufy, Kristina Buerki, Marie-Louise Karlsson, Mikaella Konstantinou, Myrto Nikoloudaki, Souzi Makri, Ulrike Erstling, Una Martin.Disclosure of InterestsAndrea Marques: None declared, Cristiano Matos: None declared, Polly Livermore Consultant of: Nordic Pharma, Grant/research support from: GOSH NIHR BRC and NIHR Personal Fellowship, Elena Nikiphorou Speakers bureau: Celltrion, Pfizer, Sanofi, Gilead, Galapagos, AbbVie, Lilly, Fresenius, Paid instructor for: Celltrion, Pfizer, Sanofi, Gilead, Galapagos, AbbVie, Lilly, Fresenius, Grant/research support from: Lilly, Pfizer, Ricardo J. O. Ferreira Speakers bureau: MSD, Sanofi, Amgen, Roche, Paid instructor for: UCB, Consultant of: medac, abbvie, roche, Sanofi, Amgen, Grant/research support from: Abbvie, medac, Amgen.
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Eckardt, Jan-Niklas, Christoph Rollig, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Frank P. Kroschinsky et al. "Prediction of Complete Remission and Survival in Acute Myeloid Leukemia Using Supervised Machine Learning". Blood 138, Supplement 1 (5 novembre 2021): 108. http://dx.doi.org/10.1182/blood-2021-149582.
Testo completoAbstract (sommario):
Abstract Achievement of complete remission (CR) signifies a crucial milestone in the therapy of acute myeloid leukemia (AML) while refractory disease is associated with dismal outcomes. Hence, accurately identifying patients at risk is essential to tailor treatment concepts individually to disease biology. Machine Learning (ML) is a branch of computer science that can process large data sets for a plethora of purposes. The underlying mechanism does not necessarily begin with a manually drafted hypothesis model. Rather the ML algorithms can detect patterns in pre-processed data and derive abstract information. We used ML to predict CR and 2-year overall survival (OS) in a large multi-center cohort of 1383 AML patients who received intensive induction therapy using clinical, laboratory, cytogenetic and molecular genetic data. To enable a customizable and reusable technological approach and achieve optimal results, we designed a data-driven platform with an embedded, automated ML pipeline integrating state-of-the-art software technology for data management and ML models. The platform consists of five scalable modules for data import and modelling, data transformation, model refinement, machine learning algorithms, feature support and performance feedback that are executed in an iterative manner to approach step-wisely the optimal configuration. To reduce dimensionality and the the risk of overfitting, dynamic feature selection was used, i.e. features were selected according to their support by feature selection algorithms. To be included in an ML model, a feature had to pass a pre-determined threshold of overall predictive power determined by summing the normalized scores of the feature selection algorithms. Features below the threshold were automatically excluded from the ML models for the respective iteration. In that way, features of high redundancy or low entropy were automatically filtered out. Our classification algorithms were completely agnostic of pre-existing risk classifications and autonomously selected predictive features both including established markers of favorable or adverse risk as well as identifying markers of so-far controversial relevance. De novo AML, extramedullary AML, double-mutated (dm) CEBPA, mutations of CEBPA-bZIP, NPM1, FLT3-ITD, ASXL1, RUNX1, SF3B1, IKZF1, TP53, U2AF1, t(8;21), inv(16)/t(16;16), del5/del5q, del17, normal or complex karyotypes, age and hemoglobin at initial diagnosis were statistically significant markers predictive of CR while t(8;21), del5/del5q, inv(16)/t(16;16), del17, dm CEBPA, CEBPA-bZIP, NPM1, FLT3-ITD , DNMT3A, SF3B1, U2AF1, TP53, age, white blood cell count, peripheral blast count, serum LDH and Hb at initial diagnosis as well as extramedullary manifestations were predictive for 2-year OS. For prediction of CR and 2-year OS, AUROCs ranged between 0.77 - 0.86 and 0.63 - 0.74, respectively. We provide a method to automatically select predictive features from different data types, cope with gaps and redundancies, apply and optimize different ML models, and evaluate optimal configurations in a scalable and reusable ML platform. In a proof-of-concept manner, our algorithms utilize both established markers of favorable or adverse risk and also provide further evidence for the roles of U2AF1, IKZF1, SF3B1, DNMT3A and bZIP mutations of CEBPA in AML risk prediction. Our study serves as a fundament for prospective validation and data-driven ML-guided risk assessment in AML at initial diagnosis for the individual patient. Image caption: Patient features were automatically selected by machine learning to predict complete remission (CR) and 2-year overall survival (OS) after intensive induction therapy. Based on a continuous feature support metric with a predefined cut-off of 0.5 (determined by optimal classification performance), 27 and 25 features were automatically selected for prediction of CR (A) and 2-year OS (C), respectively. For each of these features predicted by machine learning, odds ratios and 95% confidence intervals (CI) were calculated for CR (B) and 2 year OS (D). BMB: bone marrow blast count; FLT3h/low: FLT3-ITD ratio, h=high>0.5; Hb: hemoglobin; karyotype, c: complex aberrant karyotype (≥ 3 aberrations); karyotype, n: normal karyotype (no aberrations); LDH: lactate dehydrogenase; PBB: peripheral blood blast count; PLT: platelet count; WBC: white blood cell count. Figure 1 Figure 1. Disclosures Schetelig: Roche: Honoraria, Other: lecture fees; Novartis: Honoraria, Other: lecture fees; BMS: Honoraria, Other: lecture fees; Abbvie: Honoraria, Other: lecture fees; AstraZeneca: Honoraria, Other: lecture fees; Gilead: Honoraria, Other: lecture fees; Janssen: Honoraria, Other: lecture fees . Platzbecker: Janssen: Honoraria; Celgene/BMS: Honoraria; AbbVie: Honoraria; Novartis: Honoraria; Takeda: Honoraria; Geron: Honoraria. Müller-Tidow: Pfizer: Research Funding; Janssen: Consultancy, Research Funding; Bioline: Research Funding. Baldus: Celgene/BMS: Honoraria; Amgen: Honoraria; Novartis: Honoraria; Jazz: Honoraria. Krause: Siemens: Research Funding; Takeda: Honoraria; Pfizer: Honoraria; art-tempi: Honoraria; Kosmas: Honoraria; Gilead: Other: travel support; Abbvie: Other: travel support. Haenel: Bayer Vital: Honoraria; Jazz: Consultancy, Honoraria; GSK: Consultancy; Takeda: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Roche: Consultancy, Honoraria; Amgen: Consultancy; Celgene: Consultancy, Honoraria. Schliemann: Philogen S.p.A.: Consultancy, Honoraria, Research Funding; Abbvie: Consultancy, Other: travel grants; Astellas: Consultancy; AstraZeneca: Consultancy; Boehringer-Ingelheim: Research Funding; BMS: Consultancy, Other: travel grants; Jazz Pharmaceuticals: Consultancy, Research Funding; Novartis: Consultancy; Roche: Consultancy; Pfizer: Consultancy. Middeke: Roche: Consultancy, Honoraria; Janssen: Consultancy, Honoraria, Research Funding; Abbvie: Consultancy, Honoraria; Pfizer: Consultancy, Honoraria; Jazz: Consultancy; Astellas: Consultancy, Honoraria; Sanofi: Honoraria, Research Funding; Novartis: Consultancy; Gilead: Consultancy; Glycostem: Consultancy; UCB: Honoraria.
Libri sul tema "Grants Pass High School (Grants Pass, Or.)"
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Grants Pass High School (Grants Pass, Or.), a cura di. Grants Pass High School centennial scrapbook: The first one-hundred years. Grants Pass, Or: Grants Pass High School, 1988.
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Santos Júnior, Valdeci dos. A pré-história do Rio Grande do Norte. Brazil Publishing, 2020. http://dx.doi.org/10.31012/978-65-87836-92-8.
Testo completoAbstract (sommario):
This work is a compilation of twelve archaeological articles published in the last fifteen years dealing specifically with aspects related to the Prehistory of the State of Rio Grande do Norte, involving study topics related to cultural remains left by past societies, with approaches on landscape archeology , lithic remains, rock art, dating and cemetery site. It fills a gap in the bibliography on Prehistory in Rio Grande do Sul for high school students, undergraduate courses in History, undergraduate courses in Archeology and the general public. The articles bring together authors with research aimed at different areas of archaeological knowledge, in a diversification that helps to understand the spatial dispersion of human occupations that are farther back in time and the typology of cultural traces left by human groups that occupied temporarily or permanently, the current North Rio Grande do Sul geographical space. The objective was to enable the reader to have a broader view on the diversity of views that encompasses the most recent archaeological research, allowing to understand the processes of human occupations in the Prehistory of Rio Grande do Norte.
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Grzywacz, Joseph G., Abdallah M. Badahdah e d. Azza O. Abdelmoneium. Work Family Balance: Challenges, Experiences, and Implications for Families. 2a ed. Hamad Bin Khalifa University Press, 2019. http://dx.doi.org/10.5339/difi_9789927137952.
Testo completoAbstract (sommario):
A key objective of the study of work-family balance detailed in this report was to build an evidence base to inform policy creation or refinement targeting work-family balance and related implementation standards to ensure the protection and preservation of Qatari families. Two complementary projects were designed and implemented to achieve this key objective. The first project was a qualitative study involving in-depth interviews with 20 Qatari working adults (10 males and 10 females). The interviews were designed to learn the meaning of work-family balance among Qataris, identify the factors shaping work-family balance or the lack thereof, and collect firsthand detailed information on the use and value of policy-relevant work-family balance sup - ports for working Qataris. The second component was a survey designed to describe work-family balance among working Qatari adults, determine potential health and well-being consequences of poor work-family balance, and characterize Qataris’ use of and preferences for new work-family balance supports. The data from the qualitative interviews tell a very clear story of work-family balance among Qataris. Work-family balance is primarily viewed as working adults’ ability to meet responsibilities in both the work and family domains. Although work-fam - ily balance was valued and sought after, participants viewed work-family balance as an idyllic goal that is unattainable. Indeed, when individuals were asked about the last time they experienced balance, the most common response was “during my last vacation or extended holiday.” The challenge of achieving work-family balance was equally shared by males and females, although the challenge was heightened for females. Qataris recognized that “work” was essential to securing or providing a desirable family life; that is, work provided the financial wherewithal to obtain the features and comforts of contemporary family life in Qatar. However, the cost of this financial wherewithal was work hours and a psychological toll characterized as “long” and “exhausting” which left workers with insufficient time and energy for the family. Participants commented on the absolute necessity of paid maternity leave for work-family balance, and suggested it be expanded. Participants also discussed the importance of high-quality childcare, and the need for greater flexibility for attending to family responsibilities during the working day. Data from the quantitative national survey reinforce the results from the qualitative interviews. Work-family balance is a challenge for most working adults: if work-fam - ily balance were given scores like academic grades in school, the majority of both males and females would earn a "C" or lower (average, minimal pass or failure). As intimated in the qualitative data, working females’ work-family balance is statistically poorer than that of males. Poor work-family balance is associated with poorer physical and mental health, with particularly strong negative associations with depression. It appears the Human Resource Law of 2016 was effective in raising awareness of and access to paid maternity leave. However, a substantial minority of working Qataris lack access to work-family balance supports from their employer, and the supports that are provided by employers do not meet the expectations of the average Qatari worker.
Capitoli di libri sul tema "Grants Pass High School (Grants Pass, Or.)"
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Balmer, Randall. "Urban Lighthouse". In Grant Us Courage, 57–66. Oxford University PressNew York, NY, 1996. http://dx.doi.org/10.1093/oso/9780195100860.003.0006.
Testo completoAbstract (sommario):
Abstract When Ogilvie talks about his life and his background, he reels off a series of mentors, beginning with his high school drama teacher back in Kenosha, Wisconsin. While an undergraduate at Lake Forest College, he fell under the influence of Bruce Larson and Ralph Osborne and, in Ogilvie’s words, “became a Christian.” Although he initially professed no denominational loyalties, Ogilvie, after studying at Garrett Evangelical Seminary at Northwestern University, felt a tug from his Presbyterian past and went off to study at New College, Edinburgh, under James Stewart, Thomas Torrance, and John Bailey, all of whom took a personal interest in the young divinity student.
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Kearney, Christopher A. "The Disengaged Middle/High School Adolescent". In Helping Families of Youth with School Attendance Problems, 103–22. Oxford University Press, 2019. http://dx.doi.org/10.1093/med-psych/9780190912574.003.0006.
Testo completoAbstract (sommario):
Chapter 6 focuses on middle and high school youth who are increasingly disengaged from school and who may be pursuing activities outside of school during school hours. Chapter 6 includes detailed recommendations for psychoeducation, family work that can include agreements for problem-solving and enhanced communication, and work with school officials to modify academic requirements in line with a particular youth’s attendance status and potential alternative pathway toward graduation. In addition, frequent consultations between school-based personnel, mental health professionals, and parents are recommended regarding a student’s attendance status, grades, required past and present academic work, and legal and other policies regarding absenteeism. Core intervention components and procedures to expand the effectiveness of these core components are covered.
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Hamburg, David A., e Beatrix A. Hamburg. "Community Service: Preparation for Socially Responsible Adulthood". In Learning to Live Together. Oxford University Press, 2004. http://dx.doi.org/10.1093/oso/9780195157796.003.0017.
Testo completoAbstract (sommario):
There is a growing trend in education that has considerable potential for fostering constructive, unselfish behavior during adolescence: community service. Supervised community service, when started in early adolescence, can play a critical role in the shaping of responsible, caring, altruistic behavior. Service programs can be organized effectively by schools, by community organizations, and by religious institutions. How we help others is crucial. We must not convey superiority over others. We must impart a sense of the mutuality of being full members of the community and sharing a common fate as human beings in a world that sometimes is insensitive and at times even cruel. In 1989, a Carnegie report on the middle grades, Turning Points, stated an important insight. Early adolescence offers a superb developmental opportunity to learn values, skills, and a sense of social responsibility important for citizenship in democracies. Every middle grade school should include youth service—supervised activity helping others in the community, ideally, in collaboration with schools—in their core instructional programs for the middle grades. Turning Points 2000, a follow-up book to the 1989 landmark report, Turning Points, provides an in-depth examination of how to improve education for the middle grades and gives practical guidance to practitioners wishing to implement the Turning Points model. The research base has grown over the past 10 years, and this chapter reflects the findings of the research. It also bridges the gap between research and practice by presenting theory in practical and understandable terms. Specific to our theme of service learning, Turning Points 2000 provides a sound argument for integrating the community into the curriculum. Mutual respect and understanding, a sense of belonging, and pride in making valued contributions to others are the essence of school and community collaboration. The Early Adolescent Helper Program (EAHP), a pioneering project initiated by the City University of New York in 1982 and led by Joan Schine, brings school personnel, community-agency staff, and the middle grade school Helpers together. An effort was clearly made to integrate the school curricula with youth in community service programs. Between 1982 and 1989, almost 700 students in 17 New York City middle and junior high schools were involved in the Early Adolescent Helper Program.
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Nzama, Smangele. "Intercontinental Collaborations and their Impact on Africa’s Higher Education". In Theorising Research, Innovation, and Internationalisation in African Higher Education, 61–97. UJ Press, 2023. http://dx.doi.org/10.36615/9781776447459-03.
Testo completoAbstract (sommario):
Higher education on the African continent has been evolving over the past two decades. Higher education refers to an educational level after graduating high school (matric), and is provided by universities, universities of technology and colleges for three or four years and at completion students are awarded degrees. Although some African countries are still faced with challenges that adversely affect higher education, there are engagements in place to assist in enhancing the quality of higher education in these African countries. One of the major challenges discussed at length by academics is that a larger number of students is seen dropping out before completing their degrees. This is due to many factors such as a lack of funding, poor family background, poverty, pregnancy etc. There are engagements in place to help students in need to fund their studies, such as bursaries and grants/scholarships, both local and international, such as the Fulbright scholarship programme.
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Pham, Tammy B., Lana E. Schapiro, Majnu John e Andrew Adesman. "Weapon Carrying Among Victims of Bullying". In Bullying and Victimization, 72–78. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/9781610022880-weapon_carrying.
Testo completoAbstract (sommario):
OBJECTIVES To examine, in a large, nationally representative sample of high school students, the association between bullying victimization and carrying weapons to school and to determine to what extent past experience of 1, 2, or 3 additional indicators of peer aggression increases the likelihood of weapon carrying by victims of bullying (VoBs). METHODS National data from the 2015 Youth Risk Behavior Survey were analyzed for grades 9 to 12 (N = 15624). VoB groups were determined by self-report of being bullied at school and additional adverse experiences: fighting at school, being threatened or injured at school, and skipping school out of fear for one’s safety. Weapon carrying was measured by a dichotomized (ie, ≥ 1 vs 0) report of carrying a gun, knife, or club on school property. VoB groups were compared with nonvictims with respect to weapon carrying by logistic regression adjusting for sex, grade, and race/ethnicity. RESULTS When surveyed, 20.2% of students reported being a VoB in the past year, and 4.1% reported carrying a weapon to school in the past month. VoBs experiencing 1, 2, or 3 additional risk factors were successively more likely to carry weapons to school. The subset of VoBs who experienced all 3 additional adverse experiences were more likely to carry weapons to school compared with nonvictims (46.4% vs 2.5%, P < .001). CONCLUSIONS Pediatricians should recognize that VoBs, especially those who have experienced 1 or more indicators of peer aggression in conjunction, are at substantially increased risk of weapon carrying.
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Carson, Nancy. "The Policy Perspective". In Access Denied, 143–48. Oxford University PressNew York, NY, 2000. http://dx.doi.org/10.1093/oso/9780195107746.003.0012.
Testo completoAbstract (sommario):
Abstract Over the past decade, given the increasing attention paid to participation in science and math, a good deal has been learned about the exposure, achievement, experience, and attitudes of minority children-as well as all children-from the fourth through the eighth grades. This is where the pipeline (to use a somewhat unfashionable but still sound metaphor) tends to narrow precipitously. By the end of this period (and sometimes even at the beginning), many children have slipped below grade level in achievement. Research dearly shows that once a child falls behind, he or she is unlikely to recover. Many children who have thus far not failed in achievement now acquire negative attitudes about the utility or appropriateness of the math/science/engineering path. High-ability minority children must prove themselves yearly to new, sceptical teachers. Peer pressure and gender issues strike with a vengeance, and schools are faced with complex structural problems. Children in the sixth or seventh grades are making choices that directly limit their futures-often without realizing it. In short, from the policy perspective this is where it breaks your heart.
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Mutlu, N. Toros. "Tides' End". In Connecting & Sharing: The Book of Selected Readings 2023. International Visual Literacy Association, 2023. http://dx.doi.org/10.52917/ivlatbsr.2023.033.
Testo completoAbstract (sommario):
Just like dreams may seem to be about anything and everything, but really are about nothing; these photographs, too, are about as anything and everything as dreams can be. A dream is distilled from your everything; it is fed from a network of memories that stretches from what you had in your breakfast today to your high school history grades, and sometimes even these two can be elemental in the same narrative. Similar to a dream structure, the images in Tides’ End were not made to be about anything in particular; and even if they once were, their meanings should be sought in artist’s past and in their own individual merit. Imposing a pseudo-bond between these images would be a betrayal to viewer’s own narrative. Once again, they are about whatever and anything you see now. If anything; I want these photographs to be the memories you never had.
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Tseng, Ching-Yu, Paul Foster, Jake Klinkert, Elizabeth Adams, Corey Clark, Eric C. Larson e Leanne Ketterlin-Geller. "Using Cognitive Walkthroughs to Evaluate the Students’ Computational Thinking during Gameplay". In Building on the Past to Prepare for the Future, Proceedings of the 16th International Conference of The Mathematics Education for the Future Project, King's College,Cambridge, Aug 8-13, 2022, 542–47. WTM-Verlag, 2022. http://dx.doi.org/10.37626/ga9783959872188.0.102.
Testo completoAbstract (sommario):
In this paper, we describe how a team of multidisciplinary researchers, including game designers, computer scientists, and learning scientists, created a learning environment focused on computational thinking using a commercial video game Minecraft. The learning environment includes a Minecraft mod, a custom companion application, and a learning management system integration. The team designed the learning environment for students in Grades 6-8. Working with a group of educators, the researchers identified eleven high-priority Computer Science Teacher Association (CSTA) standards to guide game development. The team decomposed the standards into essential knowledge, skills, and abilities. In this study, we describe how we used a cognitive walkthrough with a middle school student to investigate: (a) the ways in which the game supports student learning (b) the barriers to learning, and (c) the necessary changes to facilitate learning.
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Hrabowski, Freeman A., Kenneth I. Maton, Monica Greene e Geoffrey L. Greif. "Raising Successful African American Young Women What We Have Learned". In Overcoming the Odds. Oxford University Press, 2001. http://dx.doi.org/10.1093/oso/9780195126426.003.0010.
Testo completoAbstract (sommario):
It is important to remember that the young women in our study are successful not simply in general, but they have excelled in high school and college math and science courses and performed well on standardized tests. Their success is especially significant in the light of recent legal decisions regarding affirmative action. These decisions make it more difficult for minority children to gain admission to some of the nation’s colleges and universities. The critical challenge minority children face is that if their grades and test scores—the traditional measures of success—are not as competitive as those of their White or Asian counterparts, these underrepresented minority groups may not be able to take advantage of all the educational and career opportunities available in our society. Therefore, we must do all we can to strengthen and elevate the academic performance of these students well before they enter college. We know that schools and teachers are critical in the educational process, and understandably they receive a great deal of attention when we look at student-achievement levels. However, we need to focus much more attention on the role of families in this process, particularly in preparing daughters for success in school. Both parents and daughters agreed that parental or family support, in addition to natural ability, was a major reason for the daughters’ success. We have learned that raising African American girls to become high-achieving women in science is a complex and exciting challenge. The past six chapters have focused on what we have learned from slightly more than one hundred families of successful African American college women in science. The book uses and analyzes the voices of the parents and daughters to illuminate the journeys of these families over three generations. What emerges from their diverse perspectives and backgrounds is a rich and colorful tapestry that helps us understand the values, practices, and strategies that have led to the daughters’ success. The daughters in our study come from a variety of familial, geographic, educational, and economic backgrounds.
Atti di convegni sul tema "Grants Pass High School (Grants Pass, Or.)"
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Zhou, Yong, Cheng-Chang (Sam) Pan e Nazmul Islam. "Evaluation of Engineering Readiness and Active Rate Enhanced by Intensive Summer Bridge Program". In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53262.
Testo completoAbstract (sommario):
An engineering Summer Bridge (Engineering Summer Readiness Workshop after 2015) program has been implemented at the University of Texas at Brownsville (UTB) since summer 2012. After three years of program data accumulation, we can now track those participants from their freshman up to junior year (for those still active in UTB engineering) and further extend our study on the effect of the designed engineering summer program on a) the semester the participants take Calculus I; b) the semester the participants pass Calculus I; c) the first- and second-year engineering active rate; and d) the success rate in the selected engineering major courses of all the participants. We compared all the above mentioned data to the average data of the engineering majors at the same academic stage/level. The engineering summer bridge program was originally designed to prepare the fresh high school graduates intellectually on their math and for an early readiness for their coming engineering study. More than 90% of the targeted students are Hispanic in south Texas, and English is the second language for 86% of them. As one of the components of the University of Texas System, UTB is a minority-serving institution catering mostly to the underrepresented Hispanic population of the Lower Rio Grande Valley region. It has one of the highest concentrations of Hispanic students (both in number and percentage) compared to other universities in the nation [Table 1]. Among the overall student enrollment at the university in fall 2013, 91% are Hispanic. Most of the targeted students are academically below the top 10% in their high school graduating classes due to the pre-selection of the top 10% students by the Texas flagship universities. First-generation college-goers experience a variety of challenges as they enter and move through higher education. The Engineering Summer Bridge provides students with specific types of resources and support to ensure that they move into and through engineering study smoothly and to shorten the time for their engineering study. The 4–5 week summer bridge program at UTB intensively enhances math preparation in pre-calculus and college algebra, and also actively engages the students with the modern engineering design concepts and tools. Specific goals of the bridge programs include introducing math expectations of engineering program in the areas of College Algebra, Pre-calculus, and help students eliminate the math gap by passing the COMPASS Test as well as the Pre-calculus Test in the summer to get ready for Calculus I in the coming fall semester. The long-term goals of the ESB program aim to improve the first- and second-year retention rate and four-year graduation rate of UTB engineering majors. Study on the previous three year’s data suggests that, compared to the overall average of the students enrolling into the UTB engineering program at the same period, summer bridge program participants have statistically started and finished their Calculus I (thus becoming engineering math ready) earlier. Participants also demonstrated higher engineering interesting which was proved by the participation rate in introductory engineering projects in the first two years of their engineering study. Besides, 88% of surveyed students reported that the program was helpful and convenient, and 100% of surveyed students reported that they would recommend the summer bridge program to a friend or a fellow student. Comparison of the first- to second-year active engineering student rate also suggests the validness of the summer bridge program.
Rapporti di organizzazioni sul tema "Grants Pass High School (Grants Pass, Or.)"
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Lloyd, Cynthia B., Cem Mete e Monica J. Grant. The implications of changing educational and family circumstances for children's grade progression in rural Pakistan: 1997-2004. Population Council, 2006. http://dx.doi.org/10.31899/pgy2.1030.
Testo completoAbstract (sommario):
This Population Council working paper assesses the effects of primary school characteristics, household characteristics, and recent household economic and demographic shocks on school dropout rates during the first eight grades in rural Punjab and North West Frontier Province, Pakistan. While grade retention has improved over the past six years, dropout rates for girls remain fairly high, particularly at the end of primary school (grade five). The results of this study show clearly the complementary nature of supply and demand factors in determining grade progression in rural Pakistan, particularly for girls. The results suggest that substantial improvement in the schooling environment in rural Pakistan is required if universal primary completion is to be achieved. These improvements alone, however, will not ensure success as long as households remain poor and continue to face substantial economic and demographic risks.