Letteratura scientifica selezionata sul tema "Gene therapy"
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Articoli di riviste sul tema "Gene therapy":
Goyal, Anjana, Reena Doomra, Aayushi Garg e Kruthiventi Hemalata. "CRISPR Gene Therapy in Dentistry". Asian Pacific Journal of Health Sciences 6, n. 2 (giugno 2019): 182–83. http://dx.doi.org/10.21276/apjhs.2019.6.2.26.
Gawthorpe, Paula. "Gene Therapy Gene Therapy". Nursing Standard 17, n. 33 (30 aprile 2003): 29. http://dx.doi.org/10.7748/ns2003.04.17.33.29.b25.
M. Gordon, Erlinda, Joshua R. Ravicz, Sant P. Chawla, Christopher W. Szeto, Sant P. Chawla, Michael A. Morse, Frederick L. Hall e Erlinda M. Gordon. "CCNG1 oncogene: a novel biomarker for cancer therapy /gene therapy". Cancer Research and Cellular Therapeutics 5, n. 4 (30 agosto 2021): 01–09. http://dx.doi.org/10.31579/2640-1053/090.
Sose, Mr Aadesh S., e Mr Pramod M. Bhosale. "A Review on Gene Therapy for Cancer". International Journal of Research Publication and Reviews 4, n. 4 (aprile 2023): 3058–63. http://dx.doi.org/10.55248/gengpi.4.423.36713.
&NA;. "Gene therapy". Inpharma Weekly &NA;, n. 1161 (ottobre 1998): 12. http://dx.doi.org/10.2165/00128413-199811610-00018.
&NA;. "Gene therapy". Inpharma Weekly &NA;, n. 1184 (aprile 1999): 8. http://dx.doi.org/10.2165/00128413-199911840-00015.
Peroutka, Christina, e Joann Bodurtha. "Gene Therapy". Pediatrics in Review 41, n. 11 (novembre 2020): 606–8. http://dx.doi.org/10.1542/pir.2019-0224.
&NA;. "Gene therapy". Inpharma Weekly &NA;, n. 1120 (gennaio 1998): 4. http://dx.doi.org/10.2165/00128413-199811200-00004.
Whartenby, Katharine A., Aizen J. Marrogi e Scott M. Freeman. "Gene Therapy". Drugs 50, n. 6 (dicembre 1995): 951–58. http://dx.doi.org/10.2165/00003495-199550060-00003.
Williamson, Robert. "Gene therapy". Australian Prescriber 20, n. 3 (1 luglio 1997): 72–73. http://dx.doi.org/10.18773/austprescr.1997.062.
Tesi sul tema "Gene therapy":
Vasanwala, Farha Huseini. "Gene manipulations for cancer gene therapy". Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/289776.
Santos, João Miguel Almeida. "Gene therapy: development of a new nanocarrier system for mitochondrial gene therapy". Master's thesis, Universidade da Beira Interior, 2013. http://hdl.handle.net/10400.6/1627.
As mitocôndrias são organelos únicos pois possuem o seu próprio genoma, o ADN mitocondrial (ADNmt). Apesar de bastante pequeno quando comparado com o ADN nuclear (ADNn), mutações ao nível do ADNmt são bastante frequentes devido à falta de mecanismos de protecção e de reparação. Como consequência, citopatias e doenças associadas à mitocôndria são bastante frequentes afectando essencialmente órgãos e tecidos onde existe muito dispêndio de energia como é o caso dos músculos e do cérbero. Logo, o desenvolvimento de um novo e eficiente protocolo para terapia génica mitocondrial (MGT) é visto como uma proposta aliciante. Durante esta tese de Mestrado, tentamos criar um novo nanosistema que consiga entregar eficazmente ADN plasmídico (pDNA) à mitocôndria para que no futuro possa ser usado em terapia génica mitocondrial (MGT). Assim, este projecto de investigação pode ser dividido em três etapas principais: 1. O isolamento e purificação de três plasmídeos (pUC19, pVAX1-LacZ e pcDNA3-myc-FLNa S2152A); 2. A síntese e caracterização de nanopartículas com afinidade para a mitocôndria; 3. O estudo da capacidade das nanopartículas efectuarem transfecção celular e dirigirem-se à mitocôndria; As nanopartículas desenvolvidas, através do método de co-precipitação oferecem-nos qualidades únicas como a sua biocompatibilidade, alta eficiência de encapsulamento de ADN e baixo custo de produção. A transfecção celular foi alcançada com sucesso sendo que, tais resultados, podem contribuir em grandes avanços na correcção de defeitos mitocondriais, oferecendo-nos uma nova estratégia terapêutica no combate a diversas patologias desde o cancro, às doenças de Parkinson e Alzheimer.
Nanda, Dharminderkoemar. "Gene therapy for gliomas". [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/13140.
Hayes, E. A. L. "Anti-angiogenic gene therapy". Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603877.
Bilsland, Alan. "Telomerase directed gene therapy". Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272871.
Katabi, Maha M. "Transcriptional targeting of suicide genes in cancer gene therapy". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0021/NQ55345.pdf.
Morin, Kevin Wayne. "Scintigraphic imaging during gene therapy". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq21605.pdf.
Singwi, Sanjeev. "HIV gene therapy using nucleases". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0001/MQ46100.pdf.
Horst, Maarten ter. "Gene therapy of malignant gliomas". [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/10864.
Lau, Cara Jean. "Gene therapy for malignant gliomas". Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18478.
Les gliomes sont des tumeurs primaires de cerveau les plus communes retrouvées dans les adultes. La survie médiane des patients diagnostiqués avec la forme la plus maligne, le glioblastome multiforme (GBM), est de 9 à 12 mois et a peu changé au cours des années en dépit des avances en technologie médicale. La thérapie génique peut offrir de nouvelles solutions pour traiter cette maladie résistante. Durant nos travaux, nous avons examiné trois stratégies différentes de thérapie génique Dans notre première étude, nous avons examiné l'efficacité de la thérapie visée à corriger des anomalies communes retrouvées dans les gliomes, comprenant l'amplification/mutation de récepteurs de type tyrosine kinase (RTK) et la perte de PTEN, qui mènent en conséquence à une voie activée de PI3K/Akt. Sans PTEN, les facteurs de transcription FOXO sont inactivés, et la cellule devient résistante à l'arrêt du cycle cellulaire et à l'apoptose. En utilisant un vecteur adénoviral (AdV) exprimant une protéine activée du mutant FOXO1 (AdFOXO1;AAA.), nous avons reconstitué les signaux pour l'arrêt du cycle cellulaire et l'apoptose in vitro ainsi que in vivo. Deuxièmement, nous avons examiné la capacité thérapeutique d'un nouveau vecteur adénovirale qui a la capacité de se répliquer sans provoquer de lyse cellulaire et qui exprime en plus la protéine de fusion uracile phosphoribosyltransférase/cytosine déaminase (CU). La protéine CU peut convertir le promédicament non-toxique, le 5-fluorocytosine (5-FC) à la drogue chimiothérapeutique diffusible, le 5-fluorouracile (5-FU) qui a comme cible des cellules en division cellulaire. In vitro, les vecteurs à capacité de répliquation étaient meilleurs que ceux qui ne pouvaient pas se répliquer. In vivo, le vecteur en présence du 5-FC a prolongé la survie de deux modès animaux (avec et sans sytèmes immunitaires). Dans un dernier temps, nous avons étudié une méthode pour exprimer l'IF
Libri sul tema "Gene therapy":
Xanthopoulos, Kleanthis G., a cura di. Gene Therapy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72160-1.
Blankenstein, Thomas, a cura di. Gene Therapy. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-7011-5.
Sobol, R. E., K. J. Scanlon e E. Nestaas, a cura di. Gene Therapy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-03577-1.
Giacca, Mauro. Gene Therapy. Milano: Springer Milan, 2010. http://dx.doi.org/10.1007/978-88-470-1643-9.
Kelly, Evelyn B. Gene therapy. Westport, Conn: Greenwood Press, 2007.
NATO, Study Institute "Gene Therapy" (1997 Spetsai Greece). Gene therapy. Berlin: Springer, 1998.
Giacca, Mauro. Gene therapy. Dordrecht: Springer, 2010.
1952-, Sobol Robert E., a cura di. Gene therapy. Berlin: Springer-Verlag, 1998.
Dr, Cooper David N., e Lemoine Nicholas R, a cura di. Gene therapy. Oxford, UK: Bios Scientific Publishers, 1996.
Naff, Clay Farris. Gene therapy. A cura di Naff Clay Farris. Detroit: Thomson/Gale, 2005.
Capitoli di libri sul tema "Gene therapy":
Lee, Thomas F. "Gene Therapy". In Gene Future, 127–63. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2760-6_6.
Cornetta, Kenneth. "Gene Therapy". In Molecular Genetic Pathology, 717–29. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-405-6_29.
Douglas, Joanne T., e David T. Curiel. "Gene Therapy". In Molecular Biology of the Lung, 1–20. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8784-7_1.
Choi, Vivian W., e R. Jude Samulski. "Gene Therapy". In Vogel and Motulsky's Human Genetics, 867–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-37654-5_40.
Rohini, K. "Gene Therapy". In Advances in Biotechnology, 41–54. New Delhi: Springer India, 2013. http://dx.doi.org/10.1007/978-81-322-1554-7_4.
Khan, Manzoor M. "Gene Therapy". In Immunopharmacology, 363–96. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30273-7_11.
Tanabe, Kenneth K., e James C. Cusack. "Gene Therapy". In Surgery, 1881–900. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-57282-1_86.
Huh, Warner K., Mack N. Barnes, F. Joseph Kelly e Ronald D. Alvarez. "Gene Therapy". In Ovarian Cancer, 133–57. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4757-3587-1_6.
Swazo, Norman K. "Gene Therapy". In Encyclopedia of Global Bioethics, 1–9. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05544-2_213-1.
Taura, Akiko. "Gene Therapy". In Regenerative Medicine for the Inner Ear, 215–21. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54862-1_23.
Atti di convegni sul tema "Gene therapy":
"Advances in Gene Therapy". In International Conference on Cellular & Molecular Biology and Medical Sciences. Universal Researchers (UAE), 2016. http://dx.doi.org/10.17758/uruae.ae0916417.
. Shcherbakova, S. A., P. E. Karitskaya, A. S. Chesnokova, I. O. Karpets, I. V. Evgenov e D. V. Tseylikman. "DIFFERENTIALLY EXPRESSED GENES PREDICTING RESPONSE TO TAMOXIFEN THERAPY IN BREAST CANCER PATIENTS". In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-40.
Salimova, A. A., V. D. Drozd, D. S. Rybalko, A. A. Eldeeb, A. A. Dedovskayav e D. M. Kolpashchikov. "ANTISENSE OLIGONUCLEOTIDES RELEASING CASSETTE FOR CANCER THERAPY". In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-49.
Jiang, Xingyu. "Nanocluster-enabled Gene Therapy". In The 7th International Multidisciplinary Conference on Optofluidics 2017. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/optofluidics2017-04542.
Sakr, N. "DEVELOPMENT OF GENE THERAPY FOR CAH". In Конференция «Перспективы применения генной терапии и биомедицинского клеточного продукта» с блоком летней школы для молодых ученых. Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр эндокринологии» Министерства здравоохранения Российской Федерации, 2022. http://dx.doi.org/10.14341/gnct-2022-51.
Morgan, Jeffrey R. "Genetic Strategies for Tissue Engineering". In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-1165.
Vahedi, Golnaz, Babak Faryabi, Jean-Francois Chamberland, Aniruddha Datta e Edward Dougherty. "Modeling cyclic therapy in gene regulatory networks". In 2008 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS). IEEE, 2008. http://dx.doi.org/10.1109/gensips.2008.4555670.
Sirsi, Shashank R., Darrell Yamashiro, Jessica Kandel e Mark Borden. "Polyplex-microbubbles for ultrasound-mediated gene therapy". In ICA 2013 Montreal. ASA, 2013. http://dx.doi.org/10.1121/1.4801416.
Atsumi, N., A. Pilou, I. Pringle, RC Ashworth, C. Meng, M. Chan, DR Gill et al. "S120 Gene therapy for pulmonary alveolar proteinosis". In British Thoracic Society Winter Meeting 2017, QEII Centre Broad Sanctuary Westminster London SW1P 3EE, 6 to 8 December 2017, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2017. http://dx.doi.org/10.1136/thoraxjnl-2017-210983.126.
Mokkapati, Sharada, Jon Duplisea, Michael Metcalfe, Amy Lim, Vikram Narayan, Devin Plote, Debashish Sundi et al. "Abstract IA21: Intravesical gene therapy for NMIBC". In Abstracts: AACR Special Conference on Bladder Cancer: Transforming the Field; May 18-21, 2019; Denver, CO. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1557-3265.bladder19-ia21.
Rapporti di organizzazioni sul tema "Gene therapy":
Higgins, Paul J. Inducible Anti-Angiogenic Gene Therapy. Fort Belvoir, VA: Defense Technical Information Center, maggio 2005. http://dx.doi.org/10.21236/ada437209.
Agarwal, Nitin, Jorgen Magnus, John Kerwin, Charlotte Holmes, Sy Gebrekidan, Don Powers, Emily Moran et al. Gene therapy process manufacturing maps. BioPhorum, settembre 2020. http://dx.doi.org/10.46220/2020cgt003.
Hayward, Simon W. Therapy Selection by Gene Profiling. Fort Belvoir, VA: Defense Technical Information Center, maggio 2008. http://dx.doi.org/10.21236/ada491350.
Hayward, Simon W. Therapy Selection by Gene Profiling. Fort Belvoir, VA: Defense Technical Information Center, aprile 2005. http://dx.doi.org/10.21236/ada454306.
Hayward, Simon W. Therapy Selection by Gene Profiling. Fort Belvoir, VA: Defense Technical Information Center, aprile 2004. http://dx.doi.org/10.21236/ada426169.
Higgins, Paul J. Inducible Anti-Angiogenic Gene Therapy. Fort Belvoir, VA: Defense Technical Information Center, maggio 2004. http://dx.doi.org/10.21236/ada427186.
Baylink, David J. Gene Therapy for Fracture Repair. Fort Belvoir, VA: Defense Technical Information Center, dicembre 2003. http://dx.doi.org/10.21236/ada431895.
Segal, David J. Gene Therapy for Childhood Neurofibromatosis. Fort Belvoir, VA: Defense Technical Information Center, maggio 2014. http://dx.doi.org/10.21236/ada609751.
Buchsbaum, Donald J. Radiopharmaceutical and Gene Therapy Program. Office of Scientific and Technical Information (OSTI), febbraio 2006. http://dx.doi.org/10.2172/875908.
Lau, William. Gene Therapy for Fracture Repair. Fort Belvoir, VA: Defense Technical Information Center, maggio 2007. http://dx.doi.org/10.21236/ada474569.