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1
Thanyakhan, Sutana. "The Determinants of FDI and FPI in Thailand: a Gravity Model Analysis". Phd thesis, Lincoln University. Commerce Division, 2008. http://theses.lincoln.ac.nz/public/adt-NZLIU20080429.102238/.
Testo completoAbstract (sommario):
Thailand has been one of significant recipients of foreign direct investment (FDI) among
developing countries over the last 30 years, and has recorded rapid and sustained growth
rates in a number of different industrial categories. Thailand has shown a clear policy
transition for foreign investment over time from an import-substitution regime to an
export-oriented regime. Before the 1997 Asian Financial Crisis (1985-1996), Thailand had
the fastest growing level of exports in manufactured goods among Asian economies. FDI
plays a significant role in the Thai economy. Thailand has been pursuing different foreign
investment policies at different times depending on the development objectives and
economic situation in the country.
The main objective of this research is to evaluate the determinants of FDI and foreign
portfolio investment (FPI) in Thailand using the extended Gravity Model. Panel data is
used to estimate and evaluate the empirical results based on the data for the years 1980 to
2004. It also examines the FDI flows between different locations and their geographical
distances in Thailand. The primary research question addresses what factors motivate,
attract, and sustain the FDI and FPI in Thailand. In addition, this study also examines the
effects of the 1997 Asian Financial Crisis on the inflows of FDI and FPI into Thailand.
The results show that the inflows of FDI in Thailand, which are supply-driven, are
significantly influenced by its 21 largest investing partners. The 1997 Asian Financial
Crisis has no impact on the determinants of the inflows of FDI into Thailand, but positively
influences the inflows of FPI into Thailand. Our results also show that increases in GDP
and trade between investing partners and Thailand potentially attract more FDI and FPI
into Thailand. Investing partners closer to Thailand draw more portfolio investment into Thailand than distant partners emphasising that distance has a negative impact on the
portfolio investment but a negligible impact on the FDI.
2
Al-Mashat, Alex. "Comparison of Multiple Models for Diabetes Using Model Averaging". Thesis, Uppsala universitet, Institutionen för farmaci, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-448168.
Testo completoAbstract (sommario):
Pharmacometrics is widely used in drug development. Models are developed to describe pharmacological measurements with data gathered from a clinical trial. The information can then be applied to, for instance, safely establish dose-response relationships of a substance. Glycated hemoglobin (HbA1c) is a common biomarker used by models within antihyperglycemic drug development, as it reflects the average plasma glucose level over the previous 8-12 weeks. There are five different nonlinear mixed-effects models that describes HbA1c-formation. They use different biomarkers such as mean plasma glucose (MPG), fasting plasma glucose (FPG), fasting plasma insulin (FPI) or a combination of those. The aim of this study was to compare their performances on a population and an individual level using model averaging (MA) and to explore if reduced trial durations and different treatment could affect the outcome. Multiple weighting methods were applied to the MA workflow, such as the Akaike information criterion (AIC), cross-validation (CV) and a bootstrap model averaging method. Results show that in general, models that use MPG to describe HbA1c-formation on a population level could potentially outperform models using other biomarkers, however, models have shown similar performance on individual level. Further studies on the relationship between biomarkers and model performances must be conducted, since it could potentially lay the ground for better individual HbA1c-predictions. It can then be applied in antihyperglycemic drug development and to possibly reduce sample sizes in a clinical trial. With this project, we have illustrated how to perform MA on the aforementioned models, using different biomarkers as well as the difference between model weights on a population and individual level.
3
Löbmann, Ulrich B. H. "Einfluss von Persönlichkeitsmerkmalen gemessen anhand des Freiburger Persönlichkeitsinventars (FPI) auf postanästhesiologisches Erbrechen". [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969721331.
Testo completo
4
Cheetham, John Norman. "The Role of Morality in Religious Persecution in Indonesia during Yudhoyono’s Presidency (2004-2014)". Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16964.
Testo completoAbstract (sommario):
Acts of intolerance and persecution against religious minorities rose significantly in Indonesia during the presidency of Susilo Bambang Yudhoyono (2004-2014), despite the nation's constitutional guarantees of religious freedom. This thesis aims to understand the motivations for and justifications of the persecution of Christians and Ahmadi Muslims in the world’s largest Muslim-majority country. It details the extent of the problem, explains how it differs from previous periods, and examines the actors including Islamist activists, conservative Muslims, President Yudhoyono, his ministers, state institutions, religious minorities and the public. A key question was: what role did morality play in the rise of religious persecution in Indonesia? And further: why do people do “bad” things in the name of “good”? Drawing on Haidt's moral foundations theory, the thesis explores the ideological narratives of Islamists and situates those within global Islamist narratives. Data sources include media reports, scholarly literature on Islam, Islamism and Indonesian politics, as well as interviews conducted in 2014 in Bogor, West Java, with residents, activists and members of local Muslim and Christian faith communities, including the Ahmadiyah community. Morality is theorised as an evolved response to threat, wherein ideological narratives are created that cast outgroups as threats and sanction the ingroup’s righteous self-defence from the threat, real or imagined. In this way, morality plays a role both in motivating the persecutory actions of Islamists and in justifying those actions after the fact.
5
Faron, Matthew Leon. "Examining mechanisms of virulence gene regulation and the early host interactions in Francisella tularenisis". Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/1595.
Testo completoAbstract (sommario):
Francisella tularensis is a facultative intracellular pathogen and is the etiological agent of tularemia. One key aspect to the success of Francisella as a pathogen is ability of the organism to establish infection with a low inoculum, as few as 10 colony forming units (cfu). Essential to this process is the Francisella pathogenicity island (FPI). Several studies have been performed to understand how the FPI is regulated; however, the working model is not complete, as the signals important for regulation are unknown. Additionally, the mechanisms of the proteins MigR, TrmE, and CphA, which are important for activation of the FPI, are unknown. I initiated the study of this regulatory system by measuring the ability of various cellular stresses to activate an iglA-lacZ reporter. I identified that amino acid starvation and growth in basic pH activated expression of the reporter in both LVS and Schu S4. By combining these two stresses I was able to induce iglA-lacZ reporter expression in an additive manner. As it was previously demonstrated that ppGpp is important for stabilization of the regulatory complex that transcribes FPI genes, I demonstrated by TLC that both amino acid starvation and basic pH effected iglA-lacZ expression by increasing ppGpp. Due to the importance of ppGpp in FPI expression and because MigR, TrmE, and CphA each appear to be involved in a metabolic process: fatty acid metabolism (migR) t-RNA modification (trmE) and amino acid storage (cphA), I had hypothesized that the effect on these mutations were due to decreased levels of the small alarmone ppGpp. I compared ppGpp accumulation of LVS mutants in migR, trmE, and cphA to the parent strain and observed that loss of these genes resulted in reduced ppGpp. To better understand the importance of ppGpp synthesis in F. tularensis pathogenesis, I compared the phenotypes of these strains in primary human macrophages and two immortalized epithelial cell lines. These experiments demonstrated that although each of these strains had reduced ppGpp, there were cell line specific growth phenotypes. Mice infected with these strains survived suggesting tight regulation of the FPI is required for virulence. When similar mutations were characterized in the Schu S4 background these mutations retained their regulatory role; however, mutation of migR did not significantly decrease virulence in mice. As my data demonstrated that there are different challenges that Francisella must overcome to successfully replicate within cells, I developed an in vitro model to study the interactions of F. tularensis with human alveolar type II cells (AT-II). Interestingly, Schu S4 internalizes and replicates in these recently immortalized human AT-II cells whereas, LVS internalizes, but replicates poorly within these cells. Finally, to better understand the role of AT-II cells in vivo, I performed Transmission Electron Microscopy (TEM) of infected mice. These data confirmed that Schu S4 infected both alveolar macrophages and AT-II cells. Together, this work contributes to the understanding of how Francisella adapts to various environments by modulating virulence gene expression and highlights differences between virulent Schu S4 and LVS, which may partially contribute to virulence differences observed between strains.
6
Gebauer, Christian. "Optimierung und Herstellung von Dualband-Fabry-Pérot-Filtern mit neuartigen Schichtmaterialien". Master's thesis, Universitätsbibliothek Chemnitz, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-64017.
Testo completoAbstract (sommario):
In dieser Arbeit wurde die alte Designvariante des Fabry-Pérot-Filters (FPI4) hinsichtlich Performance und Ausbeute untersucht. Zielstellung war eine Optimierung, welche die Probleme wie Sticking, Kurzschluss zwischen Schirm und Elektrode sowie Defekte bei den Vereinzelungsverfahren beseitigen sollten. Ferner wurden eine Chipbezeichnung und eine neue geteilte Elektrode anvisiert. Ergebnis dieser Optimierung war das neue Design FPI5. Weiterhin wurde neben der Auslegung des FPI5 für das adhäsive Bonden mit SU8 eine Designvariante für das direkte Bonden realisiert. Das direkte Bonden konnte bereits bei den FPI mit zwei beweglichen Reflektorträgern erfolgreich getestet werden und soll nun auf die Designvariante mit nur einem beweglichen Reflektorträger übertragen werden. Außerdem wurde eine Überprüfung der SU8-Bondfestigkeit durchgeführt. Dabei konnte nachgewiesen werden, dass die bis dato benutzten Bondparameter nicht das Optimum bezüglich der Bondfestigkeit darstellen, da in Testverbunden mit veränderten Bondparametern bis zu 50 % höhere Bondfestigkeiten erreicht wurdenThis work presents a new design type of the older well known tunable micromachined Fabry-Pérot filter (FPI4). Compared to the previous system the new design (FPI5) aimed to avoid the problems as sticking, short circuit between the shield and the electrode as well as the malfunction in dicing and separation. Furthermore an identification mark and a new separated electrode were to be improved. The conclusion of this optimization was the new Design FPI5. The whole geometry was in addition to the adhesive bonding with SU8 moreover designed for the direct bonding, which was successfully verified in the FPI design with two moveable reflector carriers. Additionally a verification of the bonding strength at different bonding parameters was done. This verification showed that a 50 % higher bonding strength could be achieved by using the new bonding parameters in comparison to the normally used bonding parameters
7
Lecocq, Guillaume. "Approches hybrides combinant chimie complexe, description statistique et densité de surface de flamme pour la simulation aux grandes échelles de l'auto-inflammation, l'allumage par bougie et la flamme de prémélange dans les moteurs à allumage commandé". Phd thesis, INSA de Rouen, 2010. http://tel.archives-ouvertes.fr/tel-00561996.
Testo completoAbstract (sommario):
Cette thèse propose une modélisation aussi générique que possible de la combustion dans les moteurs automobiles dans un cadre de simulation aux grandes échelles. Une première étude aborde la fermeture du terme de transport non résolu pour la flamme de prémélange. Par la suite, un couplage entre les modèles ecfm-les et pcm-fpi est proposé et validé pour intégrer les effets de chimie complexe à la simulation de la flamme de prémélange. Ce travail est étendu par l'adjonction de modélisations spécifiques à l'allumage par bougie et de l'auto-inflammation, toujours en intégrant les effets de chimie détaillée. Des calculs d'application aux combustions anormales dans les moteurs à allumage commandé concluent ce travail.
8
Meyer, Lena. "The Francisella pathogenicity island : its role in type VI secretion and intracellular infection". Doctoral thesis, Umeå universitet, Institutionen för klinisk mikrobiologi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-101321.
Testo completoAbstract (sommario):
Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. After phagocytosis, this Gram-negative bacterium quickly escapes from the phagocytic compartment and replicates in the host cell cytosol. For this mode of infection, several components of the Francisella pathogenicity island (FPI) are critical. Interestingly, some FPI proteins share homology to components of Type VI Secretion Systems (T6SSs), but their assembly and functionality remains to be shown in Francisella.The thesis focused on the characterization of several of these FPI components; more specifically, how they contribute to the infection cycle as well as their possible role in the putative T6SS. We identified three unique mutants, ΔiglG, ΔiglI and ΔpdpE, which to various degrees were able to escape the phagosomal compartment, replicate in the host cytosol and cause host cell cytotoxicity. In contrast, ΔiglE as well as mutants within the conserved core components of T6SSs, VgrG and DotU, were defective for all of these processes. In the case of IglE, which is a lipoprotein and localized to the outer membrane of the bacterial cell wall, residues within its N-terminus were identified to be important for IglE function. Consistent with a suggested role as a trimeric membrane puncturing device, VgrG was found to form multimers. DotU stabilized the inner membrane protein IcmF, in agreement with its function as a core T6SS component. The functionality of the secretion system was shown by the translocation of several FPI proteins into the cytosol of infected macrophages, among them IglE, IglC and VgrG, of which IglE was the most prominently secreted protein. At the same time, the secretion was dependent on the core components VgrG, DotU but also on IglG. Although we and others have shown the importance of FPI proteins for the escape of F. tularensis, it has been difficult to assess their role in the subsequent replication, since mutants that fail to escape never reach the growth-permissive cytosol. For this reason, selected FPI mutants were microinjected into the cytosol of different cell types and their growth compared to their replication upon normal uptake. Our data suggest that not only the metabolic adaptation to the cytosolic compartment is important for the replication of intracytosolic bacteria, but also the mechanism of their uptake as well as the permissiveness of the cytosolic compartment per se.
9
EGUEH, HAYAT OMAR. "Le français populaire ivoirien dans Allah n’est pas obligé d’Ahmadou Kourouma". Thesis, Linnéuniversitetet, Institutionen för språk (SPR), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-35757.
Testo completoAbstract (sommario):
Is there one or several French languages? What about African French language? The linguistic studies on French in Africa accentuate the uniqueness of the Ivorian popular French. Since Ivorians speak many different languages and as they have no real vehicular language, they appropriated the French which was implanted and imposed at the time of the colonization. Today, we witness the presence of various types of French (acrolectal, mesolectal, basilectal) that people use as a result of the effort to adapt this foreign language to local reality. The main purpose of this study is to classify some of the different characteristic features of the Popular Ivorian French according to previous studies, then to identify those features of Popular Ivorian French in Ahmadou Kourouma’s novel Allah is not obliged. We identified fourteen characteristics which particularize Popular Ivorian French. Most of these characteristics are present in Kourouma’s Allah is not obliged but some are not. In conclusion, we can see that the Ivoirians have adapted and shapedFrench to create a language they feel at home with. They have added new expressions, neologisms and metaphors in order to better convey their messages and to better understand each others.
10
Vémola, Tomáš. "Soustava Fabry-Perotova a Michelsonova interferometru pro měření délek s femtosekundovým laserem". Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229934.
Testo completoAbstract (sommario):
The thesis deals with a design of a comparing interferometer. It concerns a setup of two interferometers, one of them is a Michelson and another a Fabry-Pérot type. This set-up is made to compare results of length measurements simultaneously performed by each of them. In the Theory, basic principles of Michelson and Fabry-Pérot interferometers are described. A special attention is paid to an innovative method of length measurement with tunable lasers and optical frequency comb. In the Practical Part, so-called Pilot Experimental Setup is described. It is a prototype that has been used to perform basic experiments on comparing of the two above mentioned methods. Based on experimental results and practical experience with the Pilot Experimental Setup, a Final Setup is designed. It comes in a form of a stand-alone instrument.
11
Paplewski, Peter. "Instabile Halogenphosphane FPO, FPS und PH2Br Erzeugung und rotationsschwingungs- spektroskopische Charakterisierung /". [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964164310.
Testo completo
12
Bonifacio, Mundaca Jenny Katherine. "Utilidad del parámetro hematológico automatizado: “fracción de plaquetas inmaduras (% FPI)”, en la evaluación de la eficacia del trasplante de progenitores hematopoyéticos en pacientes del Instituto Nacional de Enfermedades Neoplásicas periodo de agosto -diciembre del 2018". Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2019. https://hdl.handle.net/20.500.12672/11218.
Testo completoAbstract (sommario):
Manifiesta que el trasplante de progenitores hematopoyéticos (TPH) es un tratamiento empleado tanto en pacientes con tumores sólidos como en enfermedades onco-hematológicas, especialmente leucemias. Para asegurar la estabilidad del pacientes emplea marcadores predictivos de los primeros signos de arraigo y recuperación de TPH siendo principalmente el conteo absoluto de neutrófilos (CAN) y el conteo de plaquetas (PQ). En la última década, los analizadores hematológicos han introducido nuevos parámetros clínicos, como la Fracción de plaquetas inmaduras (% FPI), que determina las plaquetas reticuladas en sangre periférica. Nuestro estudio prospectivo pretende demostrar la utilidad y eficacia del % FPI como predictor de arraigo de injerto en comparación con CAN y PQ. Se realizó un estudio prospectivo analítico-observacional, obteniendo datos de los parámetros CAN, PQ, % FPI y % FRI de un analizador hematológico del laboratorio de Hematología del Instituto Nacional de Enfermedades Neoplásicas en el periodo de setiembre del 2018 a mayo 2019. Muestra: 56 pacientes con enfermedades onco-hematológicas sometidos a TPH autólogo atendidos en el Servicio de protección al paciente neutropénico- SEPIN/TAMO. La mediana en días de arraigo para CAN fue de 11 y de PQ fue 7. Para FPI ≥ 2 % fue 10 y para FPI ≥ 3.3 %, 14. FPI ≥ 2 % obtuvo arraigo antes que CAN. La mediana del día de arraigo para FRI ≥ 2.5 % fue 11 días y para FRI ≥ 5.5 % fue 12, resultando mayores en relación a los días de arraigo según CAN. Sin embargo, FRI ≥ 2.5 % obtuvo arraigo al mismo tiempo en días que CAN y éste solo fue mayor a FRI ≥ 5.5 % por un día. Se concluye que el parámetro % FPI y % FRI no fueron útiles para predecir la recuperación de respuesta medular, pues no aumentaron su valor antes que los parámetros CAN y PQ. Por lo tanto el uso de estos parámetros para predecir individualmente la recuperación hematopoyética no tiene significancia clínica.Tesis
13
Rodomsky, Caitlyn Marie. "Surface Finish on A356-T6 Cast Parts using Additive Manufactured Sand Molds". Youngstown State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1526030093287334.
Testo completo
14
Lima, Frederico Diniz. "O papel da enzima Na+,K+-ATPase no déficit cognitivo e no efeito profilático induzido pelo exercício físico após o Traumatismo Crânio-Encefálico". Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/8941.
Testo completoAbstract (sommario):
Traumatic Brain Injury (TBI) is the major cause of death or cognitive deficits in industrialized countries. Although studies have indicate that the oxidative stress and functional deficits after TBI are connected events, the mechanisms that outline the development of these cognitive deficits are, still, limited. In this context, we
investigated the involvement of oxidative stress markers (thiobarbituric acid reactive species; TBARS and protein carbonylation) and the Na+,K+-ATPase enzyme activity
on the spatial learning after one and three months from a fluid percussion injury (FPI) in rats. The results revealed that FPI increase the latency of escape and the number of the errors on the Barnes Maze Test one and three months after FPI. We also found an increase of TBARS and protein carbonylation in parietal cortex after one and three months FPI. In addition, statistical analysis revealed a decrease of the Na+,K+- ATPase enzyme activity in the parietal cortex after FPI (time-dependent). These
results suggest that cognitive impairment following FPI may result, at least in part, from increase of two oxidative stress markers, protein carbonylation and TBARS that occurs concomitantly to a decrease in Na+,K+-ATPase activity. Physical exercise, despite the involvement on the generation of the reactive oxygen species (ROS), is
used on the rehabilitation of TBI. However, although the favorable effects of physical exercise on traumatic brain injury (TBI) patients is well known, the specific
mechanisms involved in this protection after TBI has been limited. Thus, we investigated whether physical training protects against oxidative damage (measured by protein carbonylation and TBARS) and neurochemical alterations represented by immunodetection of alpha subunit and activity of Na+,K+-ATPase after FPI in cerebral cortex of rats. The results revealed that physical training protected against oxidative damage induced by FPI. In addition, physical training was effective against Na+,K+-
ATPase enzyme activity inhibition and α subunit level decrease after FPI. The Pearson correlation showed that the decrease of the catalytical levels of the Na+,K+-
ATPase enzyme α subunit is related with the increasing on oxidative stress markers. Moreover, the physical activity-related protection against free radicals induced by FPI
links with maintenance of α subunit immunocontent. These results suggest that the effective protection stimulated by physical exercise on the neuronal damage induced
by TBI has connection with the protection of the specific targets from the free radicals action, like Na+,K+-ATPase enzyme.O Traumatismo crânio-encefálico (TCE) é uma das maiores causas de morte ou déficits cognitivos nos países industrializados. Apesar de os estudos indicarem que o estresse oxidativo e os déficits funcionais que ocorrem após TCE serem eventos interrelacionados, os mecanismos que delineiam o desenvolvimento destes déficits cognitivos são, ainda, limitados. Neste contexto nós investigamos o envolvimento de marcadores de estresse oxidativo (espécies reativas ao ácido tiobarbitúrico; TBARS e carbonilação protéica) e a atividade da enzima Na+,K+-ATPase no aprendizado espacial um e três meses após um dano de percussão por fluído (FPI) em ratos. Os resultados revelaram que o FPI aumentou o tempo de latência e o número de erros no teste do labirinto de Barnes em um e três meses após FPI. Também encontramos aumento no conteúdo de TBARS e proteína carbonil no córtex parietal em um e três meses após FPI. Além disso, a análise estatística revelou uma diminuição na atividade da enzima Na+,K+-ATPase no córtex cerebral após FPI tempo dependente, sugerindo que o déficit cognitivo induzido pelo FPI se deva pela perda de funcionabilidade de enzimas presentes na células como Na+,K+-ATPase. Perda esta induzida pelo aumento na geração de radicais livres após TCE. Apesar de estar envolvido no aumento da produção de espécies reativas ao Oxigênio (ERO), exercício físico tem sido utilizado na reabilitação de após TCE. Por outro lado, ainda são escassos na literatura estudos que evidenciam a especificidade dos mecanismos envolvidos na proteção induzida pelo exercício físico após TCE. Desta forma, investigamos se o treinamento físico protege contra o dano oxidativo bem como das alterações neuroquímicas representadas pela imunodetecção da subunidade α e da atividade da enzima Na+,K+-ATPase no córtex cerebral de ratos. Os resultados revelaram que o treinamento físico protegeu contra o dano oxidativo induzido por FPI. Além disso, o treinamento físico foi efetivo contra a inibição da enzima Na+,K+-ATPase e a diminuição dos níveis da sua subunidade α após FPI. A correlação de Pearson revelou que a diminuição dos níveis catalíticos da subunidade α da enzima Na+,K+-ATPase se correlaciona com o aumento dos marcadores de estresse oxidativo. Além disso, a proteção exercida pela atividade física contra os radicais livres induzidos por FPI tem relação com a manutenção do imunoconteúdo da subunidade α. A partir destes achados, sugere-se que a efetiva proteção exercida pelo exercício físico no dano neuronal causado induzido pelo TCE se deva pela proteção de alvos específicos a ação de radicais livres, como a enzima Na+, K+-ATPase.
15
Liu, Fei. "Réactions de fluoration de dérivés azotés insaturés en milieu superacide". Poitiers, 2010. http://theses.edel.univ-poitiers.fr/theses/2010/Liu-Fei/2010-Liu-Fei-These.pdf.
Testo completoAbstract (sommario):
L'utilisation des milieux superacides modifiant la réactivité des substrats organiques permet d'effectuer de nouvelles réactions et d'accéder rapidement à des produits originaux difficilement accessibles par les méthodes classiques. Il est alors possible de réaliser de nombreuses transformations directes, notamment des réactions de fluoration originales. Ce travail est consacré à l'étude de la réactivité de dérivés azotés insaturés en milieu superacide HF/SbF5 et en particulier au développement de nouvelles méthodes de fluoration de ce type de composés. Basée sur la formation d'intermédiaires dicationiques superélectrophiles, une nouvelle réaction d'hydrofluoration a été développée. L'utilisation de l'activation superélectrophile en milieu superacide a également permis la synthèse originale de sulfonamides cycliques et/ou fluorés. Après identification d'intermédiaires réactionnels polycationiques par analyse RMN in situ, une nouvelle méthode de synthèse de dérivés azotés gem-chlorofluorés et gem-difluorés a finalement été élaboréeIn superacid the reactivity of organic substrates is strongly modified and new reactions can be performed, which allows a rapid access to original products. In these conditions, multiple direct transformations occur and especially original fluorination reactions. This work was devoted to the study of the reactivity of unsaturated nitrogen derivatives in superacid (HF/SbF5) and to the development of new methods of fluorination of these compounds. Based on the formation of superelectrophilic dicationic intermediates, a new reaction of hydrofluorination has been developed. The use of superelectrophilic activation in superacid also allowed the original synthesis of benzofused sultams and/or fluorinated sulfonamides. After identification of reaction polycationic intermediates by NMR in situ analysis, a new synthetic route to gem-chlorofluoro nitrogen derivatives or gem-difluoro nitrogen derivatives has finally been set up
16
Ampuero, Juan Sebastián, Walter Javier Olguín, Sebastián Ariel Ruiz e Gonzalo Ariel Sorroche. "FMI". Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Económicas, 2020. http://bdigital.uncu.edu.ar/16426.
Testo completoAbstract (sommario):
El endeudamiento público es una herramienta muy utilizada, sobre todo en países deficitarios como Argentina. Uno de los organismos que brinda este tipo de financiamiento, y al que han recurrido frecuentemente los gobiernos de nuestro país es el Fondo Monetario Internacional. Es producto de esta recurrencia que surge la importancia de analizar esta organización, cuáles son sus funciones, y específicamente, intensificar el estudio sobre último acuerdo establecido. Todo préstamo genera intereses, y por ello es necesario generar los recursos para cubrirlos, como también su capital. El objetivo de esta tesina es lograr entender y definir cuál es la vinculación entre la tasa de endeudamiento de acuerdos establecidos y la tasa de crecimiento requerida. Esta tesina es de tipo descriptiva y correlacional, ya que detalla el problema observado y las causas que llevaron a la situación analizada y, por otro lado, se efectúa un análisis de la vinculación entre las variables que se plantean en el problema. Se trata de un estudio no experimental ya que se observan las variables tal y como suceden en su contexto natural. La metodología combina técnicas cualitativas, como el análisis de documentos, bibliografía y notas periodísticas, con técnicas cuantitativas en base al análisis de indicadores económicos. Los resultados indican que, si bien existen países con un alto índice de endeudamiento que cuentan con economías y tasas de crecimiento positivas, estos son una excepción a la regla. Y por lo general, los países que recurren frecuentemente al endeudamiento entran en un círculo vicioso del que les es dificultoso salir, especialmente en países con economías inestables y subdesarrolladas como la de nuestro país.Fil: Ampuero, Juan Sebastián. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Olguín, Walter Javier. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Ruiz, Sebastián Ariel. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Sorroche, Gonzalo Ariel. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
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Vasconcelos, Fernanda Roberta Cavalcanti de. "Papai foi pra roça, mamãe foi trabalhar". reponame:Repositório Institucional da UFSC, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/95700.
Testo completoAbstract (sommario):
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Jurídicas, Programa de Pós-Graduação em Direito, Florianópolis, 2011Made available in DSpace on 2012-10-26T05:08:22Z (GMT). No. of bitstreams: 1 299945.pdf: 1334904 bytes, checksum: 9ab24c06cdd0c13cb576b68fabc77f52 (MD5)
O mundo do trabalho precarizado e flexibilizado repercute sobre a saúde e o caráter do trabalhador e incide no contexto familiar, ecoando negativamente na efetivação dos direitos da criança e do adolescente. Diante disso, esta pesquisa propõe a expansão da aplicação da Doutrina da Proteção Integral no Direito do Trabalho, dentro de um enfoque baseado na concepção do princípio da conciliação trabalho-família. Em um primeiro momento, apresentou-se a Doutrina da Proteção Integral e a necessidade de sua expansão. Ainda se estudou, sob a perspectiva do Modelo Bioecológico do desenvolvimento humano de Uire Bronfenbrenner, a família e o desenvolvimento infantil. Em um segundo momento, analisaram-se as relações de trabalho hodiernas, o processo de precarização e flexibilização do labor e seus impactos sobre a saúde e o caráter do trabalhador. Posteriormente, em um terceiro momento, verificaram-se as repercussões do mundo do trabalho dos pais sobre o desenvolvimento infantil, levando-se em consideração o impacto sobre os fatores materiais e imateriais da família que interferem sobre o desenvolvimento da criança e do adolescente. Por fim, no último momento, fez-se a proposta da expansão da aplicação da Doutrina da Proteção Integral de forma transversal no Direito do Trabalho, dentro de um enfoque principiológico baseado na concepção do princípio conciliação trabalho-família. Nesse âmbito, fez-se o cotejo das medidas conciliação trabalho-família existentes no Brasil e em Portugal, destacando-se o mister da implantação de tais medidas sob o viés do melhor interesse da criança, abandonando-se a concepção adultocêntrica a fim de proteger os fatores materiais e imateriais indispensáveis ao desenvolvimento infantil, os quais tem sido, nos tempos coevos, impactados pelo processo de precarização/flexibilização das relações de trabalho que repercute no ambiente laboral dos pais
The world of labor that is precarious and flexible impacts the worker´s health and character and impacts the family context. It has negative repercussions to the efetivation of children´s rights. In face of that this research proposes the expansion of aplication of the Doctrine of Integral Protection in the Work´s Law inside the concepcion of the principle of work-family conciliation. At first, was presented the Doctrine of Integral Protection and the need for its expansion. Still, family and child developmente had been studied from the perspective of the Bronfenbrenner´s Bioecological Model of human development. In a second step, was analyzed the relationships of today's world of work, the process of precariousness and flexibility of labor and its impacts on health and character of the worker. Later, in a third time, was studied the repercussions of the parent´s workplace in child development, taking into account the impact on tangible and intangible factors of family that affect the development of children and adolescents. Finally, at the last moment, was presented the proposal of expanding the application of the Doctrine of Integral Protection transversely in Labour Law, in a principled approach based on the design principle of work-family conciliation. In this context, had been maden the comparison of workfamily conciliation measures in Brazil and in Portugal, especially the craft of implementing such measures under the bias of the child's best interest, abandoning the adult-design in order to protect tangible and intangible factors essential for child development, which has been, actually, impacted by the process of precariousness / flexibility of labor relations that resonates in the work environment of the parents
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Busanello, Guilherme Lago. "O EFEITO DA SUPLEMENTAÇÃO COM CREATINA SOBRE O DEFICIT COGNITIVO INDUZIDO PELO TRAUMATISMO CRANIOENCEFÁLICO EM RATOS JOVENS". Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/6728.
Testo completoAbstract (sommario):
Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorBy definition Traumatic brain injury (TBI) is a common involvement in all societies and covers the entire set of processes that alone or in combination can damage the brain. In children and adolescents TBI is an interruption in their normal development, with estimates ranging from 200 to 500 cases per 100,000 per year. Most cases are characterized as mild, with few long-term consequences, however, a significant portion of young people suffer more serious injuries. Furthermore, Juvenile TBI is the major cause of death and disability in children and adolescents. An important factor is that the sports and youth have always been closely related. In this sense, it called attention traumas, especially for young people during practice of contact sports such as martial arts, football, ice hockey, baseball. Because of the wide variety of conditions associated with TBI, there is considerable interest in the development and subsequent application of biochemical markers that relate the severity of brain damage with the development of neurological problems such as memory and learning deficits. In this context, this study aimed, at first, to see if the young animals subjected to TBI had cognitive impairment fifteen days after the injury and whether creatine supplementation has protective effect by changing the activity of CK enzyme, modulating the expression of AMPK protein, CREB, p-CREB and BDNF involved in cognitive impairment and histological damage generated by TBI To this end the present study used young male Wistar rats at 35 days of life subjected to TBI or subjected to all processes except TBI were divided into four groups which were randomized to receive the Cr supplementation (300 mg / kg po) was suspended in 0.5% CMC or vehicle (CMC) twice daily for a period of 14 days. it was shown that animals on submitted to TBI showed a reduction in cognitive functions evaluated by 15 days object recognition task after TBI. The animals that received creatine supplementation did not have their compromised functions. Our biochemical data revealed that the activity of the enzyme creatine kinase was increased fifteen days after trauma, in the same period the TBI did not alter the expression of AMPK however creatine supplementation increased its expression, suggesting a connection between CK and AMPK after TBI, since the creatine supplementation was effective in raising the activity of CK while increased expression of AMPK also caused a significant increase in the ratio of CREB and p-CREB in animals that were supplemented. We also note the participation of BDNF, whose expression this increases the animals submitted to the TBI and were supplemented with creatine, protection evidenced by creatine in lesion volume induced by the TBI.
Por definição o Traumatismo Cranioencefálico (TCE) é um acometimento comum em todas as sociedades e abrange todo o conjunto de processos que sozinhos ou em combinação podem danificar o encéfalo. Em crianças e adolescentes o TCE representa uma interrupção em seu desenvolvimento normal, com estimativas que variam de 200 a 500 casos para cada 100.000 ao ano. A maioria dos casos é caracterizada como leve, com poucas consequências a longo prazo, entretanto, uma porção significativa de jovens sofrerá ferimentos mais graves. Além disso, o TCE juvenil é a principal causa de morte e incapacidade em crianças e adolescente. Neste sentido, chama-se a atenção traumas sofridos, principalmente por jovens durante pratica de esportes de contato como as artes marciais, o futebol americano, hóquei no gelo, baseball. Devido a grande variedade de condições associadas ao TCE, há um considerável interesse no desenvolvimento e posterior aplicação de marcadores bioquímicos que relacionem a gravidade do dano cerebral com o desenvolvimento de problemas neurológicos, como déficits de memória e aprendizado. Neste contexto, o presente trabalho teve como objetivo, verificar se o se os animais jovens submetidos ao TCE apresentavam déficit cognitivo quinze dias após a lesão e se a suplementação com creatina possui efeito protetor, alterando a atividade da enzima CK, modulando a expressão das proteínas AMPK, CREB, p-CREB e BDNF envolvidas no déficit cognitivo e no dano histológico gerado pelo TCE. Para tal o presente estudo utilizou ratos Wistar jovens machos aos 35 dia de vida submetidos ao TCE ou submetido a todos os processos exceto o TCE, foram divididos em quatro grupos onde foram aleatoriamente separados, para receber a suplementação com Cr (300 mg / kg, p.o), suspensa em CMC a 0,5% ou veículo (CMC) duas vezes ao dia por um período de 14 dias. Foi evidenciado que os animais submetidos ao TCE apresentaram uma redução nas funções cognitivas avaliadas pela tarefa de reconhecimento de objeto 15 dias após o TCE. Já os animais que receberam a suplementação com creatina não tiveram suas funções comprometidas. Nossos dados bioquímicos revelaram que a atividade da enzima creatina quinase estava aumentada quinze dias pós-trauma, no mesmo período o TCE não alterou a expressão de AMPK porem a suplementação com creatina aumentou sua expressão, sugerindo uma conexão entre CK e AMPK após o TCE, uma vez que a suplementação com creatina foi efetiva em elevar a atividade da CK ao mesmo tempo que elevou a expressão de AMPK, também causou um aumento significativo na razão entre CREB e p-CREB nos animais que foram suplementados. Observamos também a participação do BDNF, cuja expressão esta aumenta nos animais que foram submetidos ao TCE e foram suplementados com creatina, na proteção evidenciada pela creatina no volume da lesão induzida pelo TCE.
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Marchal-Duval, Emmeline. "Identification de PRRX1 (Paired Related Homeobox Protein-1), un nouveau facteur de transcription impliqué dans la Fibrose Pulmonaire Idiopathique". Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC326.
Testo completoAbstract (sommario):
La Fibrose Pulmonaire Idiopathique (FPI), est une maladie pulmonaire chronique, sans aucune thérapeutique curative à l’heure actuelle. Les fibroblastes sont les cellules clés du développement de la fibrose. D’origine mésenchymateuse, la régulation de leur phénotype est toujours assez peu comprise et parmi les régulateurs possibles, peu de facteurs de transcription (FT) spécifiques de ces cellules ont été découverts. Nos travaux mettent en évidence pour la première fois, l’implication du FT mésenchymateux PRRX1 dans la régulation du comportement aberrant des fibroblastes et dans le développement de la fibrose pulmonaire. In vitro, PRRX1 favorise l’acquisition d’un phénotype pro-fibrosant des fibroblastes, avec l’induction de leur prolifération, de leur survie et de leur différenciation en myofibroblastes.In vivo, l’inhibition de PRRX1 par stratégie antisens diminue le développement des lésions fibrotiques et la déposition des protéines de collagène, de fibronectine et d’actine du muscle lisse dans le poumon des souris induites par la bléomycine. L’ensemble de ce travail a donc permis d’identifier PRRX1 comme un nouveau régulateur des fibroblastes au cours de la FPI et dont l’inhibition pourrait être une ouverture thérapeutiqueIdiopathic Pulmonary Fibrosis (IPF) is a chronic pulmonary devastating disease, with no current therapeutic available. Fibroblasts are key cells driving fibrogenesis during IPF. From mesenchymal origin, their phenotype regulation is still poorly understood. And among the potential regulators, only few transcription factors (TF) are specific to these cells. Our work demonstrates for the first time, the implication of the mesenchymal TF PRRX1 in the regulation of fibroblast phenotype during IPF development. In vitro, PRRX1 induce proliferation, survival and myofibroblast differentiation. In vivo, the PRRX1 inhibition by antisens strategy lead to attenuate fibrotic lesions and extracellular matrix deposition of collagen, fibronectine, and smooth muscle actin of bleomycin lung mice. Here we identify PRRX1 as a new fibroblast transcription factor regulator during IPF, and inhibit it could be a promising therapeutic
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Lannutti, Luigi. "Are returns on Foreign Direct Investment (FDI), FDI determinants?" reponame:Repositório Institucional do FGV, 2015. http://hdl.handle.net/10438/15546.
Testo completoAbstract (sommario):
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Foreign Direct Investments (FDI) acquired an important role in the development process of the global economy. FDI inward stock was equivalent to an average of 32% of GDP for OECD countries in 2013. However, FDI affects a country’s Balance of Payments (BoP) in two ways: FDI flows are recorded in the BoP financial account while returns on FDI affect the BoP current account. Therefore, part of the positive contribution of inward FDI to a country on its financial account could be potentially offset by a negative contribution of FDI returns on the current account. The intent of this work is to complement the research on FDI determinants by introducing FDI returns as a variable in a gravity model where bilateral FDI outflows are the dependent variable. Moreover, using outward FDI flows as the dependent variable, the work allows looking at the behavior of Multinational Corporations (MNC) investing abroad. The results show that MNCs repatriate returns generating from the investments they make abroad. This is particularly true when high-income countries are involved: MNCs from high-income countries repatriate returns to their home countries from FDI made anywhere, while MNCs from middle-income countries repatriate returns from FDI in high-income countries. Repatriated returns are a relevant variable determining the value of FDI that a country makes in another country. The information on FDI returns is starting to become available to the public. This allows MNCs to sharpen their investment location decision models and national IPAs to better assess the two-fold BoP effects of promoting FDI.
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Bernard, Olivier. "Caractérisation de l'effet cytoprotecteur des cellules souches mésenchymateuses sur l'apoptose et sur les altérations phénotypiques des cellules épithèliales alvéolaires soumises à l'hypoxie". Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCD072/document.
Testo completoAbstract (sommario):
La fibrose pulmonaire idiopathique (FPI) et le syndrome de détresse respiratoire aiguë (SDRA) de l’adulte constituent des affections sévères du poumon distal, avec un pronostic sombre pour les patients. A ce jour, aucun traitement n’est réellement efficace. De manière intéressante, une hypoxie alvéolaire est retrouvée dans ces pathologies.La thérapie cellulaire utilisant des cellules souches mésenchymateuses humaines (CSMh) pourrait représenter un intérêt thérapeutique chez l’Homme. Cependant, leurs mécanismes d’action sont multiples et encore mal définis. Aussi, nous avons testé in vitro l’hypothèse selon laquelle les CSMh pourraient exercer un effet cytoprotecteur paracrine sur les cellules épithéliales alvéolaires (CEA) soumises à l’hypoxie.Dans une première étude, nous avons montré qu’une exposition prolongée à l’hypoxie telle que celle rencontrée au cours de la FPI induisait des modifications phénotypiques des CEA primaires de rat, évocatrices d’une transition épithélio-mésenchymateuse (TEM). On observe une perte progressive d’expression des marqueurs épithéliaux (TTF1, AQP5, ZO-1 et E-Cadhérine), couplée à l’apparition tardive de marqueurs mésenchymateux (α-SMA et Vimentine). Ces modifications phénotypiques s’accompagnent de l’expression dès les premières heures d’hypoxie de facteurs de transcription impliqués dans la TEM (SNAI1, TWIST1 et ZEB1) ou induits par l’hypoxie (HIF-1α et HIF-2α), et de protéines induisant la TEM (TGF-β1 et CTGF). La co-culture des CEA avec des CSMh en fond de puits prévient les modifications phénotypiques induites par l’hypoxie ainsi que l’expression des facteurs pro-TEM TWIST1, ZEB1, TGF-β1 et CTGF. Cet effet bénéfique des CSM est en partie expliqué par la sécrétion d’un facteur de croissance épithélial, le KGF.Dans une deuxième étude, nous avons confirmé que les CEA entraient en apoptose en condition hypoxique, via l’induction de deux voies de signalisations hypoxiques pro-apoptotiques. D’une part, les facteurs de transcription induits par l’hypoxie HIF sont stabilisés, et une cible pro-apoptotique, Bnip3, est induite. D’autre part, l’hypoxie induit une accumulation d’espèces réactives à l’oxygène délétère pour la cellule, perturbant l’équilibre redox de la cellule, endommageant l’ADN, et conduisant à l’apoptose. Cette accumulation pourrait résulter notamment d’une diminution de l’activité des enzymes anti-oxydantes SOD, en hypoxie. Le manque d’oxygène entraine également l’expression de CHOP, facteur de transcription pro-apoptotique impliqué dans le stress du réticulum endoplasmique, qui va13inhiber l’expression de la protéine anti-apoptotique Bcl-2. Nous avons montré que la culture des CEA en présence de milieu conditionné de CSMh (mc-CSMh) permet de prévenir partiellement l’apoptose des CEA en hypoxie, en modulant la voie de signalisation HIF, et en prévenant l’accumulation et les effets délétères des ROS. L’effet protecteur des CSM impliquerait le KGF comme observé lors de la première étude, mais également le HGF.Ces deux études indiquent que les CSMh sont susceptibles d’exercer des effets cytoprotecteurs paracrines vis-à-vis des CEA soumises à l’hypoxie aiguë ou prolongée, en limitant d’une part les modifications phénotypiques évocatrices de TEM, et d’autre part l’apoptose des CEA via la modulation des voies de signalisations hypoxiques. La sécrétion par les CSMh de KGF et de HGF, facteurs de croissance épithéliaux connus pour leurs effets bénéfiques sur les CEA, explique en partie les effets protecteurs paracrines des CSMh. Nos résultats suggèrent que les effets cytoprotecteurs des CSMh vis-à-vis des CEA pourraient contribuer aux effets bénéfiques des CSMh observés in vivo dans différents modèles animaux de fibrose induite, ou lors d’agressions alvéolaires aiguësAcute or chronic alveolar injuries provoke massive apoptosis of alveolar epithelial cells (AEC) that compromises an efficient repair of the alveolar epithelium and leads to lung diseases such as ARDS or IPF. These disorders are commonly associated with local alveolar hypoxia aggravating their progression through the stimulation of AEC apoptosis. Administration of allogenic mesenchymal stem cells (MSCs) has been shown to limit lung inflammation and fibrosis in murine models of alveolar injury, through a still poorly understood paracrine mechanism. In a first study, we showed that long term exposure of AEC in hypoxia leads to phenotypic alterations which looks like epithelio-mesenchymal transition (EMT). Co-culture with MSCs prevent hypoxia-induced EMT.In a second work, we studied whether MSC could protect AEC from hypoxia-induced apoptosis and the mechanisms involved. hMSC-conditioned media (hMSC-CM) significantly reduced hypoxia-induced apoptosis of AEC. Such a anti-apoptotic effect was also obtained with ROS scavenger N-acetylcystein or HIF1a inhibitor YC-1. hMSC-CM decreased the protein expression of HIF1α and HIF2α and of their pro-apoptotic target Bnip3 in hypoxic AEC. hMSC-CM also reduced ROS accumulation in hypoxic AEC by enhancing the activity of anti-oxidant enzymes and prevented the induction of CHOP, a pro-apoptotic factor induced by ROS signaling. The paracrine effect of hMSC was partly dependent on KGF and HGF secretion. hMSC prevent via a paracrine effect hypoxia-induced apoptosis of AEC by modulating hypoxic and ROS signaling.These two studies show that MSCs exert cytoprotective effects in vitro against hypoxia-induced apoptosis and EMT in AEC
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Jurek, Martin. "Austria´s FDI". Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-16572.
Testo completoAbstract (sommario):
This diploma thesis focuses on Austrian foreign direct investments and more specifically on the internalization of Austrian companies into the Czech Republic. The aim is to thoroughly display the Austria's outward foreign direct investments, introduce the internationalization models and apply them in an analysis of Austrian companies present in the Czech Republic. The first step towards answering research questions is the presentation of a short theoretical background on foreign direct investment. Further, the main characteristics of Austrian investments are stated. Chapter two starts with term definitions. Thereby, a common under-standing of the most relevant terms is established. The thorough literature review illuminates the theories behind each model and its development. In the following step, the practical part of the paper is introduced. At first, assumptions from the internationalization models are derived. Afterwards, these assumptions serve as a foundation for the questionnaire's framework. The primary part of this chapter displays results of the empirical study. Finally, a conclusion is presented summing up the thesis's core findings. These findings are primarily direct answers to the research questions seeking to fulfill the main objective of the diploma thesis.
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Rydqvist, Johan. "FDI and Currency Crises : Currency crises and the inflow of FDI". Thesis, Jönköping University, Jönköping International Business School, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-71.
Testo completoAbstract (sommario):
The purpose of this thesis is to analyse if there are any changes in the inflow of Foreign Direct Investments before, during and after a currency crisis. The thesis is based on a theoretical framework and has an empirical part, which use a regression equation.
The theoretical framework presents a foundation of the incentives to mak FDI investments and the implications for a host country. Together with the possible link to the level of the real exchange rate in the host country, this thesis, based partly on previous paper written on the subject, presents a regression equation for an empirical analysis. The regression equation is based on a hypothesis about the changes in FDI inflow before, during and after the occurrence of a currency crisis in the host country.
The empirical analysis presents different results concerning the link between FDI and a currency crisis. The hypothesis stated in the thesis is that a currency crisis influences FDI inflows. This hypothesis is rejected. Moreover, a currency crisis can have both positive and negative effects on the inflow of FDI for the selected countries.
Results find further no similarities in regions or year of occurrence of the currency crises. The depth, length and structure of each currency crisis together with using the right definition of a currency crisis are two important factors relating to the outcomes in this study.
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Birtch, Thomas Alexander. "The competitive advantage of FDI : a dynamic OLI view of FDI strategy". Thesis, University of Cambridge, 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709488.
Testo completo
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Tomblin, Josh. "Buried FPR-Concrete Arches". Fogler Library, University of Maine, 2006. http://www.library.umaine.edu/theses/pdf/TomblinJX2006.pdf.
Testo completo
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Floucat, Yves. "Philosophie et foi chretienne". Toulouse 2, 1988. http://www.theses.fr/1988TOU20067.
Testo completoAbstract (sommario):
Cette these rassemble, pour l'essentiel, un certain nombre de travaux publies ou a paraitre qui traitent tous, par quelque cote, du theme central : le rapport de la reflexion philosophique avec la foi chretienne. Le premier volume, entierement inedit, porte sur la dimension naturellement religieuse de la sagesse metaphysique qui, de l'etre comme habens esse, s'eleve jusqu'a l'etre meme subsistant qui est pur exister. Cette dimension religieuse, qui concerne certes l'ordre d'exercice et non pas l'ordre de specification, montre au moins la possibilite philosophique de la "philosophie chretienne". L'ouverture de la philosophie sur la sagesse chretienne integrale, tout entiere suspendue aux virtualites theologiques et mystiques de la foi, stabilise la raison dans une harmonie naturelle avec le desir religieux qui lui permet le plein developpement de ses energies metaphysiques. Dans une telle perspective peut etre elaboree une anthropologie chretienne integrale qui fait droit aux aspirations les plus radicales de l'esprit pour l'absolu, notamment la religion et la sagesseThis dissertation assembles a certain number of writings (already published or forthcoming), wich treat different aspects of the same basic theme : the relation of philosophical reflection to the christian faith. The first volume treats of the natural religious dimension of metaphysical wisdom, which starts its consideration with being as habens esse and from there rises to subsistent being, the pure act of existing. Although this religious dimension characterizes the concrete exercise of metaphysical wisdom and not its objective specification, it nevertheless demonstrates at the very least the philosophical possibility of a "christian philosophy". When philosophy is open to integral christian wisdom (which is itself a direct expression of the theological and mystical virtualities of faith), reason is then stabilized in a natural harmony with religious desire which assists it in attaining a full development of its inherent metaphysical capacities. This perspective makes the elaboration of an integral christian anthropology possible because it accounts for the most fundamental aspirations of the human spirit to the absolute, notably religion and wisdom
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Floucat, Yves. "Philosophie et foi chrétienne". Lille 3 : ANRT, 1989. http://catalogue.bnf.fr/ark:/12148/cb37613653j.
Testo completo
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Kim, Jae-Yeon. "The evolution of South Korean outward FDI : internationalisation strategies, FDI motives, and location choice". Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/98021/.
Testo completoAbstract (sommario):
This thesis aims to contribute to the understanding of the relationships between foreign direct investment (FDI) motives and the location choice of internationalising firms. Based on data from South Korea, this thesis comprises three empirical chapters examining, from different aspects, South Korean internationalisation. The first empirical chapter is conceptualised work, exploring how South Korean firms invest abroad. It covers the way in which South Korean firms give consideration to 1) the economic structure and the dynamic country specific advantages in the host and home countries, 2) the growth of firms in emerging countries, and 3) their own competitiveness through the strategic- use of assets such as technology. These location choice strategies very with the host countries. Additionally, it examines the Korean outward FDI model by distinguishing between the motives for FDI, and discusses the development over time of the relationship between South Korean FDI motive and location choice, and it then identifies trends. The second empirical chapter analyses, by motive, factors that influence South Korean firms to locate their foreign subsidiaries in China. It discusses the factors by province, and takes into account the impact of the global financial crisis upon the location choice (by Chinese province) of South Korean firms. The third chapter studies how South Korean firms locate their FDI in the United States in order to obtain a strategic asset. It examines the relative importance of various location determinants of Korean high-tech industries and knowledge-intensive services. Specifically, the empirical works study how Korean firms internationalise. South Korean outward FDI in developing countries is mainly for the purpose of efficiency-seeking and export promotion motives; these transform over time to efficiency-seeking and market-seeking. On the other hand, the initial motivations for investing in developed countries were strategic asset-seeking and export promotion motives; these then developed into strategic asset-seeking and market-seeking FDI.
29
Perraki, Marina. "The misconception of F.I. Schechter". Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8615.
Testo completoAbstract (sommario):
After briefly examining the history of trade marks and establishing the theoretical framework of trade mark functions, an analysis from the perspective of semiotics is conducted, viewing the trade mark as a sign. This analysis serves as a tool for the suggestions and conclusions drawn in relation to the role of trade mark law today. The issues of trade mark registration, use and protection are examined, as main facets of the trade mark functions. An analysis of the legal provisions, legal doctrine and case law on trade mark registration and use in Greece, before and after the entry into force of the First Council Directive on the Harmonisation of trade mark laws in Europe 89/104/EEC is undertaken, so as to denote the effect of the European harmonisation on these issues. The Court of Justice case law is examined, in juxtaposition to the Greek case law on the respective implementing provisions. The similarities and differences are noted and analysed. Throughout, examples from a common law jurisdiction, namely the UK, are taken into account. The issues of risk of confusion and dilution are analytically examined at a national (Greek) and European level. In comparison to the Court of Justice jurisprudence, the national legal framework and case law of Greece on these issues is analysed. Examples from other European jurisdictions are taken into account. The theory of dilution in the context of the European trade mark framework is further analysed against developments in the USA. The controversial doctrine of trade mark dilution, introduced by Fr. I. Schechter, is of primary interest in the course of the thesis and suggestions are made for a new perspective of the theory. The controversial doctrine of Schechter is seen, in view of the above, under a new light.
30
Mallak, Wissam. "Les programmes d'ajustement du FMI". Paris 2, 1993. http://www.theses.fr/1993PA020068.
Testo completoAbstract (sommario):
Dans le cadre de cette these les programmes d'ajustement du fonds monetaire international (fmi) sont abordes dans un contexte juridico-economique l'analyse a englobe les politiques de gestion de la demande et les politiques axees sur l'offre. En outre, les effets economiques nationaux et internationaux des programmes d'ajustement ont ete l'objet d'une etude approfondie corroboree par deux cas d'application concernant la coree du sud et la cote d'ivoire.
31
Ouattara, Niho. "La mauvaise foi de l'assuré". Nice, 1986. http://www.theses.fr/1986NICE0015.
Testo completoAbstract (sommario):
La notion de mauvaise foi de l'assuré se présente essentiellement sous deux formes. Tantôt, c'est la connaissance de l'inexistence du risque proposé. C'est le cas lorsque l'assuré demande la garantie pour un risque qui s'est déjà réalisé, ou lorsque la chose objet du contrat a disparu avant la formation de la police. Tantôt aussi c'est l'intention de tromper l'assureur qui implique la mauvaise foi. Celle-ci se manifeste soit à travers les déclarations relatives au risque, soit à travers les déclarations relatives au sinistre. Peu importe que les déclarations de l'assuré aient été précédées ou corroborées par des actes matériels. L'intention de tromper suffit à caractériser sa mauvaise foi. Cette mauvaise foi intention de tromper s'identifie à la fraude. Enfin, il arrive que la mauvaise foi de l'assuré coïncide avec le délit d'escroquerie. C'est le cas lorsque les moyens qui ont permis sa réalisation correspondent à ceux prévus par l'art. 405 du code pénal (faux nom, fausse qualité ou mise en scène) mais quel que soit son mode d'expression, la mauvaise foi ou fraude de l'assuré cause toujours un préjudice a l'assureur et à la mutualité des assurés de sorte qu'il a fallu prévoir des sanctions pour l'endiguer. Ces sanctions sont d'abord civiles (nullité, déchéance). Elles peuvent aussi être pénales (amende, emprisonnement ou interdiction de certains droits). Mais ces sanctions, en raison d'une part de la présomption de bonne foi édictée par l'art. 2268 du code civil, et d'autre part de la réticence des juges à admettre la mauvaise foi de l'assuré, ne jouent pas le rôle que l'on pourrait attendre d'elles. Aussi serait-il souhaitable de porter l'accent sur la prévention; laquelle pourrait permettre de limiter sensiblement les manifestations de la mauvaise foi ou fraude de l'assuréThe notion of dishonesty is presented essentially in two forms. Sometimes, it is the acquaintance of the non-existence of the risk proposed. It is the case when the assured claims the guarantee for a risk which has been already realized, or when the subject of the contract has disappeared before the formin gof the policy. Othertimes, it is the intention to deceive the insurer which involves dishonesty. This one appears either throughout the declarations related to the risk, or throughout the declarations related to the disaster. It doesn't matter much whether the declarations of the assured have been preceded or corroboted by materiels acts ; the intention to deceive is enough to characterize his dishonesty. This dishonesty is synonymous with fraud. Finally, it happens that dishonesty coincides with swinding offence. It is the case when the means which permitted it's realization ocrrespond to those planned by the art. 405 of the penal code (false name, false quality, production). But whatever may be his form, the dishonesty or fraud of the assured always causes an injury to the insurer and to the mutuel of the assured ; that's why sanctions have been planned to hold it back. These sanctions are at first civil sanctions (nullity, forfeiture). They can also be penal sanctions (fine, imprisonnement or prohibition of certains rights). But because first of the presomption of honesty decreed by the art. 2268 of the civil code, and moreover of the judge's reserve to admit the dishonesty of the assured, these sanctions are not efficient enough. So it is desirable to emphasize prevention, which one could permit to restrict approximately the manifestations of dishonesty or fraud
32
Rifaï, Fadilé-Sylvie. "La présomption de bonne foi". Thesis, Montpellier 1, 2010. http://www.theses.fr/2010MON10041.
Testo completoAbstract (sommario):
La présomption de bonne foi a une valeur légale, puisqu’elle est consacrée par le législateur dans l’article 2274 du code civil. Cette thèse est consacrée à l’étude de la bonne foi-croyance erronée pour cerner son contenu et préciser son régime juridique, étant donné que cette notion est toujours accusée d’être floue et vague. La croyance erronée résulte des éléments objectifs matériels significatifs de vérité et invasifs de l’état d’esprit de sa victime. Le critère de la prise en considération et de la protection de cette dernière est la légitimité de la croyance erronée qui qualifie la bonne foi. Lorsque la croyance erronée est légitime, la présomption de bonne foi est consolidée et peut, par conséquent, déployer tous ses effets juridiques. La bonne foi qualifiée jouit, ainsi, d’un pouvoir protecteur et créateur de droits subjectifs qui porte atteinte à la puissance et à l’effectivité de la loi et de certains principes juridiques. La bonne foi a également une fonction fondatrice de certaines règles légales. Cependant, la puissance normative de la présomption de bonne foi consolidée n’est pas absolue ; elle est limitée par la préséance de certaines règles légales qui ne peuvent céder à la fonction créatrice et protectrice de la bonne foi qui est, ainsi, sacrifiée au profit de certains intérêts supérieursThe presumption of good faith has a legal value, because it is consecrated by the legislature in the section 2274 of the civil code. This thesis concerns only good faith-erroneous belief and tries to precise its content and juridical rule, as this notion is always accused to be blurred and vague. Erroneous belief is the result of objective material elements which are significant of trust and invasive of the state of mind of the victim. The erroneous belief needs a degree of legitimity in order to qualify the good faith and give rise to juridical protection. Where the erroneous belief is lawful, the presumption of good faith is consolidated and can spread all its juridical effects. The good faith has, therefore, a power of creation of rights. This power involves a breach of the law and of certain principles of the civil law. The good faith is also the basis of somme legal rules. However, the normative power of the good faith is not absolute ; it’s limited by the hold of some legal rules which sacrify the good faith in order to protect superior interests
33
Ouattara, Niho. "La Mauvaise foi de l'assuré". Lille 3 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376001626.
Testo completo
34
Palmyre, Danielle. "Culture créole et foi chrétienne /". Beau-Bassin (Maurice) : Bruxelles : [Paris] : M. Pike ; Lumen vitae ; [diff. du Cerf], 2007. http://catalogue.bnf.fr/ark:/12148/cb41347800v.
Testo completoAbstract (sommario):
Texte remanié de: Thèse de doctorat--Théologie--Louvain-la-Neuve (Belgique)--Université Catholique, 2004. Titre de soutenance : Culture créole et foi chrétienne à l'Île Maurice.En appendice, choix de documents. Bibliogr. p. 262-277.
35
Cavrini, Guido. "Il ruotamento nelle configurazioni FPL". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8767/.
Testo completoAbstract (sommario):
La Congettura di Razumov-Strogranov, dimostrata solo nel 2010 con metodi puramente combinatori da due matematici italiani, Contini e Sportiello, ha affascinato molti studiosi di combinatoria che si sono dedicati allo studio delle configurazioni FPL. In questa tesi viene studiato il ruotamento, una speciale permutazione delle configurazioni FPL con determinate condizioni al bordo che è lo strumento fondamentale per la dimostrazione della sovramenzionata congettura.
36
Al, Jaber S. A. "Analysis of FDI in UAE". Thesis, Coventry University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511443.
Testo completo
37
Dobiášková, Veronika. "Strategie rozvoje podniku FPO s.r.o". Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2010. http://www.nusl.cz/ntk/nusl-222495.
Testo completoAbstract (sommario):
This diploma thesis is dealing with creating compact description of strategic documentation in a company. It helps to set one direction, where the company should be heading in its vision, function, identity, objectives and values. It is a compact collection for strategic development of the company and for keeping the direction towards the chosen objectives set beforehand. It is possible to secure coordination and mutual belonging of the parts and objective of the company in a framework of unanimous material.
38
Hellqvist, Christian, e Martin Boman. "Swedish FDI in Africa : Locational determinants of FDI from the perspective of the OLI paradigm". Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176158.
Testo completoAbstract (sommario):
The global flows of foreign direct investment (FDI) to Africa have increased steadily in recent years but the research on what determines the location of these investments is scarce. Research focusing on FDI flows from small and open economies such as Sweden is even more uncommon. From the locational factors found in the OLI paradigm we developed a model that was tested on a dataset of 25 African countries over the period of 2007 to 2010. The model proved inadequate in explaining the African inward FDI flows from Sweden. However, it well explains the aggregated inward FDI flows from firms around the world to Africa. Our results implies that the locational determinants derived from the OLI paradigm are inadequate in explaining Swedish FDI flows to Africa and maybe even in explaining flows from a small and open economy to developing countries. The answer to the question of what locational determinants are important for Swedish companies investing in African countries should perhaps be sought for elsewhere.
39
Lukac, Dusko. "Key success factors for Foreign Direct Investment (FDI) the case of FDI in western Balkan". Hamburg Diplomica-Verl, 2005. http://d-nb.info/988912082/04.
Testo completo
40
Lukac, Dusko. "Key success factors for Foreign Direct Investment (FDI) : the case of FDI in western Balkan /". Hamburg : Diplomica-Verl, 2008. http://d-nb.info/988912082/04.
Testo completo
41
Xu, Fei-Fei [Verfasser]. "Synthetic Oligosaccharides as Tools to Investigate Bacterial Capsular Polysaccharides and Teichoic Acids / Fei-Fei Xu". Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1160235759/34.
Testo completo
42
Bruckner, Dean C. "Automatic pulse shaping with the AN/FPN-42 and AN/FPN-44A Loran-C transmitters". Thesis, Monterey, California : Naval Postgraduate School, 1992. http://handle.dtic.mil/100.2/ADA257860.
Testo completoAbstract (sommario):
Thesis (M.S. in Electrical Engineering)--Naval Postgraduate School, December 1992.Thesis Advisor: Tummala, Murali. "December 1992." Description based on title screen as viewed on April 16, 2009. Includes bibliographical references (p. 181-183). Also available in print.
43
Ma, Chi-kin Patrick. "The death of Yue Fei (1103-1142) a critical study = Yue Fei si yin yan jiu /". Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/hkuto/record/B31952239.
Testo completo
44
Chorell, Hugo, e Emma Nilsson. "Chinese FDI in the Oil Sector : Can they be explained by the prevalent theory on FDI?" Thesis, Uppsala University, Department of Economics, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6352.
Testo completoAbstract (sommario):
China has experienced a phenomenal growth during the last years. With this economic
development comes a great need for energy. Energy to fuel the domestic production. As the
domestic resources in China have shown to be insufficient, one way to get the energy
demanded is to go onto the international market. China has, thus, started undertaking FDI in
oil to be able to feed the domestic needs. In this thesis we will discuss these investments and
investigate if prevalent theories on FDI can explain the FDI that have taken place. Our
conclusion is that the FDI undertaken has been resource-seeking investment. Since the
Chinese oil companies are state-owned and regulated so that they can not act as profitmaximizing
firms, our thesis will show that the Chinese FDI in the oil sector therefore only
partly can be explained by the theories on FDI.
45
Ratiphokhin, Rattiya. "Empirical Analysis of the Determinants of FDI in Thailand : A Case Study of FDI from Singapore". Thesis, Södertörns högskola, Institutionen för samhällsvetenskaper, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-9392.
Testo completoAbstract (sommario):
The thesis analyzes the determinants of Singaporean foreign direct investment in Thailand during the years 1981-2009, taking into account the relevant previous studies. The research comprises of analyzing the patterns of Singapore’s OFDI to Thailand, literature reviews of theories and empirical studies of Singaporean OFDI in general, and also an econometric analysis of the determinants of Singapore’s total FDI in Thailand. Singapore is the largest overseas investors in Thailand when compare to other countries in ASEAN. More specifically, Singaporean investors make the decision to invest abroad, in this case is Thailand, base on home country factors and host country factors. In terms of home country factors, Singaporean FDI in Thailand is caused by the limited Singapore’s domestic market and also rapid changing in the comparative advantages of Singapore. While, for host country factors, the econometric approach is utilized to observe in this study. In form of econometric analysis, the two regression models with time series data between the years 1981 and 2009 are employed to analyze. To be exact, in the first regression model, the Singaporean FDI in Thailand (RFDI) is treated as the dependent variable, while the growth rate of Thai domestic market (GRGDP), the Thai real wage rate (RWAGE), the relative price of Thailand and Singapore (PTS), the nominal relative exchange rate (EXR) and the dummy variable of the Asian crisis (AC) are treated as dependent variables. While, in the second model, RFDI is also the dependent variable but PTS and EXR are combined to be the real relative exchange rate of Thailand and Singapore or RER (PTS*EXR). However, in order to reach the conclusion of observing the determinants of Singaporean FDI in Thailand, OLS technique is utilized in two regression models. The OLS results present that GRGDP, PTS and RER have an influence on RFDI. Further, the long run relationship between the variables is also observed in this study by using the Johansen cointegration test. The results of the test indicate that there are conintegrating equations or the long-run relationships among the variables in model 1 and model 2. Apart from that, the Error Correction Mechanism (ECM) is also employed with the purpose of illustrating that when RFDI of two models deviate from their long- run equilibrium, an adjustment to pull the actual RFDI to the long-run equilibrium will take place. However, empirical evidences present that the speed of adjustment is rather rapid in both of models.
46
Liu, Xuepeng. "Essays on trade, FDI and development". Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2006. http://proquest.umi.com/login?COPT=REJTPTU0NWQmSU5UPTAmVkVSPTI=&clientId=3739.
Testo completo
47
Zhou, Ying. "The impact of corruption on FDI". Thesis, University of Birmingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522062.
Testo completo
48
Cheung, Man-keung, e 張文強. "FBI-1 and choriocarcinoma cell proliferation". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193565.
Testo completoAbstract (sommario):
Gestational trophoblastic disease (GTD) includes a spectrum of diseases that involve abnormal growth of trophoblastic cells inside the uterus. It can range from benign hydatidiform moles (HM) to frankly malignant choriocarcinoma, placental site trophoblastic tumor (PSTT) or epithelioid trophoblastic tumour (ETT).GTD are considered curable if the patient is correctly diagnosed and receive appropriate treatment during the early stage of the disease.
About 15% -30% of hydatidiform moles will develop persistent GTD, but majority of them can usually resolved by surgical intervention and post-operation weekly serial serum β-hCG level monitoring. In contrast, choriocarcinoma is a frankly malignant gestational trophoblastic neoplasm (GTN). Most choriocarcinoma arise from HM but can develop from any pregnancy related events such as ectopic pregnancy, live-birth or stillbirth. Being the most aggressive neoplasm in GTD, choriocarcinoma can develop widespread metastasis and can be fatal.
FBI-1 (Pokemon) is a transcription factor that is often overexpressed in various types of human cancer. We have reported overexpression of FBI-1 in ovarian cancer in association with cell proliferation and invasiveness. Our recent study also suggested that overexpression of FBI-1 in HM was related to subsequent development of gestational trophoblastic neoplasms(GTN).
In this study, we evaluated the role of FBI-1 inchoriocarcinoma cell proliferation. By MTT assay, the proliferation rates of two choriocarcinoma cell lines (JAR and JEG-3) was found to decrease when FBI-1 was downregulated by shRNA approach with statistical significance reached in JEG-3 (p < 0.05). By quantitative real time PCR, the relative levels of a panel of hedgehog pathway related genes, including SHH, SMO, GLI1, GLI2, GLI3, and KIF7 were assessed after knockdown of FBI-1 gene. Sonic hedgehog (SHH) was found to be consistently downregulated in JEG-3 and JAR transfected with FBI-1 shRNA constructs.
In conclusion, FBI-1 may play a role in choriocarcinoma cell proliferation and FBI-1 may be explored as a potential therapeutic target for GTD in the future.published_or_final_version
Pathology
Master
Master of Medical Sciences
49
Jia, Fei. "FDI linkage : impacts, determinants, and policies". Thesis, University of Surrey, 2007. http://epubs.surrey.ac.uk/724/.
Testo completo
50
Groffe, Julie. "La bonne foi en droit d'auteur". Thesis, Paris 11, 2014. http://www.theses.fr/2014PA111016.
Testo completoAbstract (sommario):
La bonne foi, notion floue teintée de morale et issue du droit commun, a vocation à intervenir dans toutes les branches du droit. A ce titre, elle trouve naturellement à s’appliquer en droit d’auteur, c’est-à-dire au sein du droit qui organise la protection des rapports entre l’auteur et l’œuvre de l’esprit qu’il a créée, en reconnaissant à ce dernier des droits patrimoniaux et des droits extrapatrimoniaux. Notion duale, la bonne foi s’entend tantôt comme la croyance erronée dans une situation – c’est là la dimension subjective –, tantôt comme l’exigence de loyauté dans le comportement, ce qui renvoie à la dimension objective. Le choix est opéré, au sein de la présente étude, d’embrasser la notion dans sa globalité et non de se concentrer sur l’une ou l’autre des faces de la bonne foi. L’enjeu de la thèse étant d’analyser comment une notion de droit commun peut intervenir au sein d’un droit spécial, il semblait en effet judicieux de ne pas décomposer la notion mais au contraire d’accepter sa polymorphie. La difficulté tient au fait que la bonne foi – dans sa dimension subjective comme dans sa dimension objective – est bien souvent absente de la norme du droit d’auteur, de sorte qu’une première analyse pourrait laisser penser que la notion n’a pas de rôle à jouer en ce domaine. Cependant, il apparaît finalement que cette dernière est bien présente au sein de ce droit spécial, que son intervention soit d’ailleurs positive – auquel cas la notion est prise en compte et reconnue – ou, au contraire, négative (ce qui revient alors à l’exclure volontairement des solutions). Les manifestations de la bonne foi se présentent, en ce domaine, sous deux formes. D’une part, elles peuvent être propres au droit d’auteur : la notion intervient ainsi dans les raisonnements relatifs à la détermination du monopole, droit exclusif reconnu au titulaire de droits, mais également dans les règles applicables à la sanction des atteintes portées à ce droit exclusif. L’utilisation de la notion procède alors d’un choix du juge ou, plus rarement, du législateur et répond à un objectif interne au droit spécial, objectif qui sera bien souvent celui de la défense de l’auteur ou, plus largement, du titulaire de droits. D’autre part, les manifestations de la bonne foi peuvent être importées du droit commun. Si le lieu d’intervention privilégié de la notion en telle hypothèse est le contrat d’auteur (c’est-à-dire le contrat qui organise l’exploitation de l’œuvre) du fait de l’applicabilité de l’article 1134, alinéa 3, du Code civil – lequel impose une obligation de bonne foi dans l’exécution du contrat – aux droits spéciaux, la bonne foi peut aussi s’épanouir au-delà de ce contrat. Le recours à la notion est, dans ce cas, imposé au juge et au législateur spéciaux – lesquels doivent naturellement tenir compte de la norme générale dès lors que celle-ci n’est pas en contradiction avec le texte spécial – et l’objectif poursuivi est alors externe au droit d’auteur : il peut ainsi être question de protéger l’équilibre des relations ou encore de garantir la sécurité juridique des rapports. Plurielles, les interventions de la bonne foi en droit d’auteur invitent ainsi à s’interroger sur les interférences entre droit commun et droit spécialGood faith, vague notion which refers to morality and that is derived from common law, can occur in all branches of law. As such, it is naturally applicable in French copyright law, which is the special law that provides the protection of the relationship between the author and the work that he created and that recognizes moral rights and economic rights in favour of the author. Good faith has a double definition: it means both a misbelief in a situation – that is the subjective dimension – and a requirement of loyalty, which refers to its objective dimension. The choice has been made, in this study, to embrace the whole concept instead of focusing on one or the other side of good faith. Because the aim of this thesis is to analyze how a concept of common law can intervene in a special law, it seemed wise to accept its polymorphism instead of deconstructing the concept. The difficulty is that good faith – in its objective dimension as in its subjective dimension – is often absent from the special law: as a consequence, a first analysis might suggest that this concept has no role to play in this area. However, it finally appears that the notion does exist in French copyright law, whether its intervention is positive (and in that case good faith is taken into account and recognized) or negative (in which case the concept is deliberately excluded from the solutions). The expressions of good faith arise in two forms in this field. On one hand, they may be specific to French copyright law: the concept can be used to answer the questions related to the determination of the exclusive right that is granted to the holder of rights, or the questions related to the penalties for copyright infringement. In these hypotheses, the use of good faith is a choice made by the judge or, more rarely, by the legislator and it fulfills a specific objective, proper to French copyright law: this objective is often the defense of the author or, on a wider scale, the right holder. On the other hand, the expressions of good faith can be imported from common law. If the privileged place of intervention in that case is the author’s contract (which is the contract that organizes the exploitation of the work), due to the applicability of the article 1134, paragraph 3, of the French Civil code – which imposes a duty of good faith during the performance of the contract –, good faith also has a part to play beyond this contract. In these cases, the use of the concept is imposed to the judge and the legislator – because both must take into account the general rule when it is not in contradiction with the special one – and the aim is to fulfill a general objective, external to French copyright law: then the goal is to protect the balance of relationships or to guarantee legal certainty. As a consequence, the expressions of good faith in French copyright law are plural and call for questioning the interference between common law and special law