Letteratura scientifica selezionata sul tema "Ferroportin-1"
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Articoli di riviste sul tema "Ferroportin-1"
Nekhai, Sergei, Namita Kumari, Min Xu, Altreisha Foster, Sharmin Diaz e Victor R. Gordeuk. "Ferroportin Q248H Mutation Protects From HIV-1 Infection in Vitro". Blood 120, n. 21 (16 novembre 2012): 993. http://dx.doi.org/10.1182/blood.v120.21.993.993.
Testo completoKumari, Namita, Seyed Mehdi Nouraie, Hatajai Lassiter, Asrar Ahmad, Kathryn Anastos, Jason Lazar, Seble Kassaye et al. "Control of HIV-1 Infection By Ferroportin Q248H Mutation". Blood 134, Supplement_1 (13 novembre 2019): 953. http://dx.doi.org/10.1182/blood-2019-128685.
Testo completoNekhai, Sergei, Altreisha Foster, Min Xu, Xiaomei Niu, Jamie Rotimi e Victor R. Gordeuk. "Inhibition of HIV-1 by Ferroprotin Expression." Blood 112, n. 11 (16 novembre 2008): 1464. http://dx.doi.org/10.1182/blood.v112.11.1464.1464.
Testo completoLiu, Xiao-Bing, Funmei Yang e David J. Haile. "Functional consequences of ferroportin 1 mutations". Blood Cells, Molecules, and Diseases 35, n. 1 (luglio 2005): 33–46. http://dx.doi.org/10.1016/j.bcmd.2005.04.005.
Testo completoHarada, Nobuhiko, Masaya Kanayama, Atsushi Maruyama, Aruto Yoshida, Kyoko Tazumi, Tomonori Hosoya, Junsei Mimura et al. "Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages". Archives of Biochemistry and Biophysics 508, n. 1 (aprile 2011): 101–9. http://dx.doi.org/10.1016/j.abb.2011.02.001.
Testo completoAmmosova, Tatiana, Andrey Ivanov e Sergei A. Nekhai. "Ferroportin Q248H Mutation Prevents Its Ubiquitination". Blood 122, n. 21 (15 novembre 2013): 2196. http://dx.doi.org/10.1182/blood.v122.21.2196.2196.
Testo completoWallace, Daniel F., Jonathan M. Harris e V. Nathan Subramaniam. "Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype". American Journal of Physiology-Cell Physiology 298, n. 1 (gennaio 2010): C75—C84. http://dx.doi.org/10.1152/ajpcell.00621.2008.
Testo completoLakhal-Littleton, Samira. "Ferroportin Mediated Control of Iron Metabolism and Disease". Blood 128, n. 22 (2 dicembre 2016): SCI—21—SCI—21. http://dx.doi.org/10.1182/blood.v128.22.sci-21.sci-21.
Testo completoTabbah, Sammy, Catalin Buhimschi, Katherine Rodewald-Millen, Christopher Pierson, Vineet Bhandari, Philip Samuels e Irina Buhimschi. "Hepcidin, an Iron Regulatory Hormone of Innate Immunity, is Differentially Expressed in Premature Fetuses with Early-Onset Neonatal Sepsis". American Journal of Perinatology 35, n. 09 (2 febbraio 2018): 865–72. http://dx.doi.org/10.1055/s-0038-1626711.
Testo completoNekhai, Sergei A., Namita Kumari, Denitra Breuer, Charlee Mclean, Tatiana Ammosova e Subhash Dhawan. "Induction Of Ferroportin, Erg-1, p21 and IKBα In Sickle Cell Disease May Contribute To HIV-1 Inhibition". Blood 122, n. 21 (15 novembre 2013): 2250. http://dx.doi.org/10.1182/blood.v122.21.2250.2250.
Testo completoTesi sul tema "Ferroportin-1"
Brinkmann, Martin. "Expression der Eisenstoffwechselproteine Divalent-Metal-Transporter-1, Ferroportin-1, HFE und Transferrinrezeptor-1 humaner Dendritischer Zellen". [S.l. : s.n.], 2006.
Cerca il testo completoBrinkmann, Martin [Verfasser]. "Expression der Eisenstoffwechselproteine Divalent-Metal-Transporter-1, Ferroportin-1, HFE und Transferrinrezeptor-1 humaner Dendritischer Zellen / Martin Brinkmann". Tübingen : Universitätsbibliothek Tübingen, 2006. http://d-nb.info/1160307016/34.
Testo completoDebbiche, Rim. "Influence des lipides sur la dynamique du transport du fer médié par la ferroportine-1 et sa modulation par des composés amphiphiles". Electronic Thesis or Diss., Brest, 2024. http://www.theses.fr/2024BRES0006.
Testo completoFerroportin-1(FPN1), the only known mammalian iron exporter, is expressed on the surface of various specialized cells involved in iron metabolism. This protein belongs to the Major Facilitator Superfamily (MFS) and releases intracellular iron through conformational changes oscillating between an open structure towards the cytoplasm (Inward-Facing) and an open structure towards the bloodstream (Outward-Facing; OF). It has been reported that FPN1 is preferentially localized in lipid-rafts, microdomains of the plasma membrane particularly enriched in cholesterol (CHOL). Early in the thesis, we hypothesized that direct interactions between FPN1 and surrounding lipids, notably CHOL, are necessary to stabilize FPN1 in the OF conformation and/or promote certain conformational changes. I confirmed the preferential colocalization of FPN1 in the lipid rafts of human embryonic kidney cells. The dependence of FPN1's iron export function on CHOL was examined by depletion/repletion (CHOL/epicholesterol). Mutational screening experiments supported by structural analyses of the experimental 3D structure of FPN1 in an OF state have identified three possible CHOL-binding sites (of the CARC/CRAC type). Based on molecular dynamics simulations in a simplified POPC-type lipid environment, we identify certain interactions between charged residues of the human FPN1 3D structure and the polar heads of the surrounding phospholipids, which could facilitate conformational changes of the transporter. Besides, I show, for the first time, that FPN1 function is modulated by synthetic amphiphilic compounds, ohmline and its derivatives. Through the development of a novel in vitro approach (PLA: Proximity Ligation Assay), I show that ohmline delocalizes FPN1 from lipid-rafts, thereby decreasing its interaction with its functional partner, ceruloplasmin (CP), a ferroxidase that catalyzes the oxidation of ferrous iron, and consequently its iron export function
Chlosta, Sabine [Verfasser]. "Ferroportin 1 expression regulates intracellular growth of Salmonella enterica serovar Typhimurium, a link between innate immunity and hereditary hemochromatosis / Sabine Chlosta". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2008. http://d-nb.info/1022764241/34.
Testo completoThomas, Carla. "The validation and use of the rat intestinal epithelial cell line 6 (IEC-6) to study the role of ferroportin1 and divalent metal transporter 1 in the uptake of iron from Fe(II) and Fe(III)". University of Western Australia. Physiology Discipline Group, 2003. http://theses.library.uwa.edu.au/adt-WU2004.0019.
Testo completoHawula, Zachary John. "Identification and analysis of genetic and chemical modulators of iron metabolism". Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/225904/1/Zachary_Hawula_Thesis.pdf.
Testo completoVieira, Maria Silva. "Uncovering the mechanism of Ferroportin-1 downmodulation upon Leishmania infantum infection". Master's thesis, 2017. https://hdl.handle.net/10216/110544.
Testo completoVieira, Maria Silva. "Uncovering the mechanism of Ferroportin-1 downmodulation upon Leishmania infantum infection". Dissertação, 2017. https://hdl.handle.net/10216/110544.
Testo completoRice, Adrian Edward. "Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin". Thesis, 2009. https://thesis.library.caltech.edu/1883/1/Adrian_Rice_Full_Thesis.pdf.
Testo completoLibri sul tema "Ferroportin-1"
Moléculas que participan en el transporte de hierro materno-fetal : importancia del receptor 1 de transferrina y de la ferroportina en la placenta humana. Editorial Académica Española, 2012.
Cerca il testo completoCapitoli di libri sul tema "Ferroportin-1"
Pietrangelo, Antonello. "Iron transporter ferroportin FPN1". In Membrane Transporter Diseases, 123–31. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9023-5_8.
Testo completo