Tesi sul tema "Facteurs de risque – Pronostic (médecine)"
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Gilmer, Catherine. "Etude des différents facteurs intervenant sur les récidives des troubles bipolaires". Bordeaux 2, 1991. http://www.theses.fr/1991BOR23025.
Helmer, Catherine. "Aspects épidémiologiques des dém̀ences et de la maladie d'Alzheimer : facteurs de risque et pronostic". Bordeaux 2, 2000. http://www.theses.fr/2000BOR28900.
Dementia represents a major Public Health problem which care is deficient for the moment. However, several possibilities exist to face this problem. It is necessary to develop the prevention of this disease acting on its factors. We analysed the effect of several potential risk factors of dementia and Alzheimer's disease (marital status, profession, tobacco, diabetes). Some of these factors provide tracks of prevention ; others could allow to develop actions of prevention. It is of prime importance to continue analysing the risk factors of this disease on which it will be possible to act, with a particular interest for the vascular factors. In addition to prevention, it is also necessary to improve the care of the demented persons and their relatives,, as soon as the disease is diagnosed and at every stage of its evolution. Assessment of the needs of the demented population is required to improve the care, which implicates to know better the consequences of the disease. We present here the analysis of the consequences of dementia in term of mortality, carried out by using biostatistic models allowing to take into account the specific methodological difficulties of this analysis. The other major consequences of the dementia, in particular the disability and institutionalisation, will have also to be taken into account. After the phase of observation, it will be necessary to promote the intervention studies, as well in the field of prevention as in the field of care
Semjen, François. "Insuffisance rénale aigue͏̈ post-traumatique traitée par hémofiltration veinoveineuse continue : facteurs de risque et pronostic". Bordeaux 2, 1996. http://www.theses.fr/1996BOR23058.
Dall'Anese, Rémy. "Essai de détermination d'un score prédictif et pronostique de la maladie coronarienne par l'épreuve d'effort sur cycloergonomètre en analyse multivariée, à partir de 106 patients". Bordeaux 2, 2000. http://www.theses.fr/2000BOR23078.
Noboa, Maria Soledad. "La prise en compte des facteurs temps dépendants dans l'évaluation du risque de récidive de la maladie veineuse thromboembolique". Brest, 2008. http://www.theses.fr/2008BRES3073.
Gauthier, Victoria. "Étude du pronostic des accidents vasculaires cérébraux et des syndromes coronaires aigus en population : étude réalisée à partir du registre des AVC de Lille et des trois registres français des syndromes coronaires aigus". Electronic Thesis or Diss., Université de Lille (2022-....), 2023. http://www.theses.fr/2023ULILS004.
Cardiovascular diseases are an important cause of morbidity and mortality. The monitoring of epidemiological indicators of stroke and Acute Coronary Syndromes (ACS) through population registers plays an important role in the evaluation of public policies. In addition, as acute-phase care progresses rapidly over time, it is essential to be able to monitor its evolution, to estimate the potential impact of new treatments in real life. Our objective was to characterize the prognosis of strokes and ACS in the population and it was organized according to 3 axes.In a first study, we studied lethality after stroke in the Lille stroke registry. Lethality at 28 days, in subjects aged >=35 years, was 48% after hemorrhagic stroke, 3% after large artery atherosclerosis or lacunar stroke and varied from 15 to 20% for the other subtypes of ischemic strokes. In the acute phase, the time between the onset of symptoms and first contact with the care services was exceeded in 40% of patients, not allowing revascularization. Age, severity and stroke etiology were the main predictors of 28-day case fatality. The higher lethality observed in women compared to men was mainly explained by their advanced age. AF, an underdiagnosed and undertreated comorbidity found in 57% of cardioembolic strokes, was also a risk factor associated with lethality.In a second work we studied the evolution of the management and the lethality of ACS in the French registers of ACS between 2006 and 2016. In patients aged 35-74, residing in one of the 3 geographical areas monitored by MONICA registries and hospitalized for an ACS, the lethality was 8% at 28 days. These rates varied by type of ACS (9% after STEMI, 6% after NSTEMI at 1 year), but did not differ between men and women. On the therapeutic level, our results showed a more qualitative than quantitative evolution with an improvement in the effectiveness of management in the acute phase and prescriptions related to new generation therapies. However, while the characteristics of the events tend to converge between men and women, a slight deficit in management was still observed in women compared to men.In a third part, we focused on patients who had survived their incident event to study the risk of recurrence after an ACS in the French ACS registers. The recurrence rate after an incident ACS remained high (~20% over 9 years), mainly the year following the incident event (6.7%) and did not depend on the type of the first event (STEMI/NSTEMI/UA), or sex. Impaired LVEF and complications from the incident event were major risk factors for recurrence. Recurrence rates decreased between 2009 and 2017.In conclusion, acute vascular events remain diseases with a serious prognosis whose etiology and physiopathological mechanism are an important and independent source of prognostic variability. It is important to continue improving the management of women for whom the progression is not as optimal as for men and to pay particular attention to the severity factors of stroke and ACS. Thus, by providing precise epidemiological indicators, the continuous recording of acute vascular events in a geographically defined territory, has enabled the monitoring of the state of vascular health in the population and has enabled us to study the prognosis of strokes and ACS according to the precise characteristics of the event
Alcaraz-Darrou, Céline. "Stabilité et changement chez l'enfant avec autisme entre 5 et 8 ans : aspects cliniques, adaptatifs et linguistiques". Montpellier 3, 2007. http://www.theses.fr/2007MON30058.
Autism is probably a neuro-developmental disorder manifested in the three first years of the child’s life and characterised by communication, socialization and interests distortions and also by its heterogeneous clinical manifestations. Developmental psychopathology permitted to give our work a conceptual framework : the aims are to identify different developmental trajectories and to determine the predictive factors of evolution of 208 children aged from 5 to 8 years. The first part permitted to locate stability and changes of adaptative, symptomatic, and linguistic characteristics, and to identify predictive factors of the evolution of symptomatic intensity and autonomy in daily living. The second part of our work showed with more precision four developmental trajectories and two risk and protection factors in the case/event of a bad evolution. Finally, a clinical analysis showed that a same initial clinical table can generate very different developmental trajectories
Méry, Benoîte. "Complications cardiovasculaires et cancer du sein : magnitude et challenges". Electronic Thesis or Diss., Lyon, 2021. http://www.theses.fr/2021LYSES018.
Breast cancer remains the main cause or death and the most frequent cancer in women in developed countries with more than 52.000 new cases per year in France. Breast cancer and cardiovascular diseases share common risk factors and compete for the first place in morbidity and mortality, making the patient with breast cancer, a patient at high cardiovascular risk, which goes beyond cardiovascular toxicity or cancer treatments. If the prognosis of patients wilh breast cancer has improved thanks to the enrichment of the therapeuthic arsenal and generalized screening, with 5-year survival rates close to 90%, cardiovascular disease events constitute one of the most worrying complications, and can occur throughout breast cancer treatment, but also in the long term, consequently impacting. the effectiveness of treatments, prognosis and patient survival. lndeed, cardiovascular disease events represents the leading cause or death in patients with breast cancer. However, at the present time there are no specific tools making it possible to identify patients with high risk of developing a cardiovascular desease during the treatment of breast cancer and therefore for monitoring and implement preventive treatment. At the same time. there are no specific recommandations for this particular population concerning the monitoring and management or patients when cardiovascular disease events occur. This thesis aims to explore the complex interactions between breast cancer and cardiovascular pathologies, through the determination or the prevalence or cardiovascular disease events within a population with breast cancer, the identificalion of predictive risk factors for the occurrence or cardiovascular events, and external validation of a predictive score to ultimate improve the prognosis and quality of life of patients treated fort breast cancer
Juillière, Yves. "Facteurs de risque et facteurs pronostiques dans la cardiomyopathie dilatée idiopathique". Nancy 1, 1996. http://www.theses.fr/1996NAN10374.
Vinuesa-Kalonji, Pascale. "Analyse des nouveaux facteurs histopronostiques des cancers colorectaux". Montpellier 1, 1997. http://www.theses.fr/1997MON11009.
Sadoun, Catherine. "Ostéoporose : épidémiologie, facteurs de risque, traitements". Paris 5, 1995. http://www.theses.fr/1995PA05P116.
Basseau, Virginie. "Adénocarcinomes gastriques : étude critique des classifications histologiques et des facteurs histopronostiques à partir de 285 cas". Bordeaux 2, 2000. http://www.theses.fr/2000BOR23025.
Gontier, Renaud. "Facteurs pronostiques des adénocarcinomes gastriques". Bordeaux 2, 2000. http://www.theses.fr/2000BOR23032.
Zeitouni, Michel. "Athérosclérose coronaire prématurée : facteurs de risque, pronostic, prévention et nouvelles approches mécanistiques". Thesis, Sorbonne université, 2021. http://www.theses.fr/2021SORUS526.
This thesis focused on premature coronary atherosclerosis, the clinical and biological profile of affected individuals, with a pathophysiological approach aiming to assess the contribution of inflammation and vascular age. Studies 1 and 2 described the very high-risk cardiovascular profile of these patients and the factors of poor long-term outcomes. These studies have demonstrated that premature coronary atherosclerosis is a progressive disease with a rapid multi-arterial involvement, leading to a mortality rate of 20% over 10 years. Study 3 demonstrated the significant contribution of subclinical inflammation to the genesis of coronary atherosclerosis in younger individuals, compared with older populations. This observation relied on the use of a new biomarker of chronic inflammation, GlycA, a composite signal of the glycosylation of proteins in the acute phase. Study 4 demonstrated the significant involvement of IL-1β in the post-myocardial infarction inflammatory cascade, and its association with short and long-term death. Study 5 evaluated the stiffness of the aortic root measured by MRI as a new risk marker for premature coronary artery disease, introduction a new tool for an integrative measure of vascular aging. Studies 6 and 7 have highlighted the lack of performance of American and European international guidelines in detecting and treating individuals at high risk of premature atherosclerosis, and the missed opportunities for intensive treatment after a first myocardial infarction. premature
Rodolphe, Philippe. "Etude des facteurs pronostiques de la polymyosite de l'adulte : à propos de 9 observations". Bordeaux 2, 1995. http://www.theses.fr/1995BOR2M004.
Andréjak, Claire. "Infections pulmonaires à mycobactéries non tuberculeuses : incidence, facteurs de risque, pronostic et traitement". Amiens, 2012. http://www.theses.fr/2012AMIED006.
Nontuberculous mycobacteria pulmonary infections are an increasing health problem, mainly in regions with a decreasing incidence of tuberculosis. In a cohort study, nontuberculous mycobacteria pulmonary incidence in Denmark was 1. 08 per 100,000 person-years. In this population, mortality was high (40. 1% of 5-year mortality). The main prognostic factors were age, gender, comorbidities and mycobacteria specie. In a population based case-control study, the main risk factor was chronic pulmonary disease (OR 16. 5), mainly COPD (17. 5), especially if patients received inhaled corticosteroids (OR 19. 6). We have developed two murine models of aerosol infections one for M. Xenopi, the other for M. Avium. Then, we have tested different antibiotic combinations, after a first evaluation in vitro. For M. Xenopi, the amikacin-containing regimens were the most effective. No difference was found between clarithromycin- and moxifloxacin-containing regimen. For M. Avium, the most effective combination was clarithromycin, rifampicin and ethambutol. The addition of moxifloxacin did not improve the efficacy. The moxifloxacin substitution of clarithromycin has a negative impact on treatment efficacy. This work gives some answers to the numerous questions about epidemiology and treatment of nontuberculous mycobacteria infections
Arsenault, Benoît. "Facteurs de risque en émergence des maladies cardiovasculaires : de l'épidémiologie au métabolisme". Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26342/26342.pdf.
Chevalier, Laurent. "Devenir et facteurs prédictifs de mortalité chez 105 malades coronariens inopérables : comparaison avec des malades coronariens opérés". Bordeaux 2, 1993. http://www.theses.fr/1993BOR23071.
Lafragette-Négrier, Marie-Sylvie. "Facteurs pronostiques des carcinomes rénaux métastasiques". Lyon 1, 2002. http://www.theses.fr/2002LYO1T023.
Benchehida, Nassim. "Notion de typologie homéopathique : prévention des principaux facteurs de risque athérogène". Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20087.
Mindaa, Monique. "Étude des facteurs de pronostic des adénocarcinomes de l'endomètre : à partir de 175 observations". Bordeaux 2, 1989. http://www.theses.fr/1989BOR25153.
Levaché, Charles-Briac. "Facteurs pronostiques des sarcomes des tissus mous superficiels de l'adulte : étude rétrospective et multicentrique d'une série de 202 patients traités dans les centres de lutte contre le cancer". Bordeaux 2, 1998. http://www.theses.fr/1998BOR23054.
Hanslik, Bertrand. "Hépatite alcoolique aigue͏̈ : facteurs pronostiques, anatomopathologiques et clinico-biologiques : à propos de 76 cas". Montpellier 1, 1990. http://www.theses.fr/1990MON11214.
Leport, Catherine. "Facteurs pronostiques des cancers du sein à ganglions négatifs après chirurgie première". Montpellier 1, 1991. http://www.theses.fr/1991MON11193.
Benoist, Guillaume. "Infection congénitale par le CMV : apport des modèles expérimentaux et étude des facteurs pronostiques anténataux". Caen, 2012. http://www.theses.fr/2012CAEN3133.
Human cytomegalovirus (CMV) is part of the herpesviridae family. The perinatal infection that can result from this virus is the leading infectious cause of congenital malformation, mental retardation and deafness. About half the pregnant women in France are not immune to CMV. Vertical transmission of CMV is about 30%. Current resources enable doctors to diagnose CMV infection in pregnant women as well as in the fetus and newborn. Prognostic factors for CMV fetal infection are poorly understood. We were able to demonstrate the prognostic value of fetal blood sampling by showing that fetal thrombocytopenia was an independent predictor of symptomatic CMV infection and have confirmed the strong prognostic value of the existence of fetal ultrasound abnormalities. Furthermore, we demonstrated the benefit of practicing magnetic resonance imaging of the fetal brain in addition to an ultrasound examination in order to determine fetal brain abnormalities. These data enable us to refine and determining the prognosis of infected fetuses. We also assessed the replicative capacity of CMV strain AD169 on transformed cells extravillous cytotrophoblast HIPEC65. We have shown that CMV has a complete replicative cycle in this line that appears at least as permissive as the MRC5 cell system used for comparison, during the first week of culture. These results are original and show that this system is certainly very interesting to study the characteristics of placental infection with CMV
Masson, Philippe. "Etude des facteurs de risque de calcification rénale chez l'enfant broncho-dysplasique". Bordeaux 2, 1992. http://www.theses.fr/1992BOR23016.
Vincent, Pierre-Marie. "Leucémies aiguës non lymphoblastiques de l'adulte : facteurs pronostiques : à propos de 30 observations". Bordeaux 2, 1989. http://www.theses.fr/1989BOR25254.
Razavi, Darius. "Contribution à l'étude des facteurs psychologiques et psychopathologiques associés au diagnostic, au traitement et au pronostic des affections cancéreuses". Doctoral thesis, Universite Libre de Bruxelles, 1994. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212645.
Laurent, Christophe. "Facteurs de pronostic des cancers du rectum : étude uni et multi-factorielle à propos de 449 observations". Bordeaux 2, 1995. http://www.theses.fr/1995BOR23037.
Kroger, Edeltraut. "Facteurs de risque occupationnels et environnementaux de la démence : l'étude sur la santé et le vieillissement au Canada". Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25437/25437.pdf.
Baghdadli, Amaria. "Étude des facteurs de variabilité des troubles autistiques de l'enfant : vers une identification de facteurs pronostiques de l'autisme". Montpellier 1, 2001. http://www.theses.fr/2001MON1T009.
Tanguy, Marie-Laure. "Estimation bayésienne de la variation dans le temps de l'effet des facteurs pronostiques : application au cancer du sein métastasé". Bordeaux 2, 1995. http://www.theses.fr/1995BOR2P014.
Garrelon, Jean-Luc. "Facteurs de risque de fistule anastomotique après résection rectale pour cancer". Bordeaux 2, 1996. http://www.theses.fr/1996BOR23065.
Boullé, Gildas. "Les maladies parodontales : un facteur de risque additionnel pour les accouchements prématurés?" Thesis, Université Laval, 2005. http://www.theses.ulaval.ca/2005/22725/22725.pdf.
Akeke, Jean-Charles. "Pronostic des cancers du sein traités par chirurgie première ; corrélation de la protéine pS2 aux autres facteurs pronostiques dans une série de trois cent quarante trois malades". Bordeaux 2, 1993. http://www.theses.fr/1993BOR2M057.
Kayibanda, Jeanne Françoise. "La surveillance et les facteurs de risque associés au VIH au Rwanda". Thesis, Université Laval, 2011. http://www.theses.ulaval.ca/2011/28514/28514.pdf.
Thériault, Sébastien. "Prédiction précoce du risque de diabète gestationnel : développement de modèles combinant facteurs cliniques et marqueurs biochimiques". Thesis, Université Laval, 2014. http://www.theses.ulaval.ca/2014/30778/30778.pdf.
This project aims to develop an early risk-prediction tool for gestational diabetes (GDM). This is a case-control study from a prospective cohort including 7929 pregnant women recruited between 2005 and 2010 in the Quebec City metropolitan area. External validation of four predictive models proposed in the literature allowed the identification of clinical variables (including past history of GDM, body mass index and family history of diabetes) performing particularly well for the prediction of GDM requiring insulin therapy. An original model combining some of these clinical variables with three readily available biochemical markers (HbA1c, SHBG and hsCRP measured between 14 and 17 weeks of gestation) yielded area under the ROC curve of 0.90 and sensitivity of 72% at a false-positive rate of 10%. This project allowed the identification of predictive factors for GDM available early in pregnancy, which could improve the management of high risk women.
Derex, Laurent. "Étude IRM des facteurs prédictifs du pronostic clinique et du risque hémorragique des infarctus cérébraux traités par thrombolyse intraveineuse". Lyon 1, 2004. http://www.theses.fr/2004LYO10076.
Delvert, Didier. "Les facteurs prédictifs de réponse chez les malades traités pour une hépatite chronique C : à propos de quatre-vingt-deux patients". Bordeaux 2, 1993. http://www.theses.fr/1993BOR23083.
Bonvalot, Sylvie. "Résultats et facteurs de pronostic des cancers épidermoïdes de l'oesophage réséqués : à propos d'une série de 335 cas". Caen, 1990. http://www.theses.fr/1990CAEN3096.
Lachance, Philippe. "Corrélation entre certains polymorphismes génétiques et l'expression de certains facteurs de risque de maladie coronarienne". Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26472/26472.pdf.
Dion, Roy Véronique. "Facteurs de risque d'athérosclérose menant à la maladie coronarienne : l'évaluation du risque cardiométabolique chez de jeunes adultes apparemment en santé par la mesure du tissu adipeux abdominal avec imagerie par résonance magnétique". Thesis, Université Laval, 2012. http://www.theses.ulaval.ca/2012/29150/29150.pdf.
Faure, Nathalie. "Toxicité rénale des produits de contraste iodés : facteurs de risque et prévention". Bordeaux 2, 1998. http://www.theses.fr/1998BOR2P066.
Mahé, Isabelle. "Problématique des antithrombotiques chez le sujet âgé en médecine interne". Paris 5, 2003. http://www.theses.fr/2003PA05P628.
The management of antithrombotic therapy in elderly patients is a growing question : indications are diseases increasing with age, bleeding complications are most often observed in elderly. But findings of clinical trials about antithrombotic therapies not always fit with the therapeutic problematic of elderly patients who are at both increased thrombotic and haemorrhagic risk. In order to increase the benefit to risk ratio of antithrombotic therapy, several ways of research have been developed about the choice and the management of antithrombotic therapies (aspirine, low molecular weight heparins) in thrombo-embolic diseases (atrial fibrillation, venous thrombosis : prevention and treatment) in older patients recruited in internal medicine
Trillet-Lenoir, Véronique. "Identification de facteurs pronostiques au cours du cancer bronchique indifférencié à petites cellules". Lyon 1, 1991. http://www.theses.fr/1991LYO1H076.
Bruandet, Amélie. "Facteurs pronostiques de patients atteints de démence suivis en Centre mémoire de ressources et de recherche : exemple d'utilisation de bases de données médicales à des fins de recherche clinique". Lille 2, 2008. http://tel.archives-ouvertes.fr/tel-00336252/fr/.
Bloud, Raymond. "Évaluation des facteurs de variabilité du pronostic à court terme des malades lors de l'admission en réanimation polyvalente au centre hospitalier de Mont-de-Marsan : à propos de 548 cas". Bordeaux 2, 1990. http://www.theses.fr/1990BOR25206.
Kodio, Belco. "Niveaux, causes et facteurs de risque de la mortalité maternelle en milieu rural au Sénégal : 1984-1998". Bordeaux 2, 2001. http://www.theses.fr/2001BOR28849.
Objective : To assess the magnitude of maternal mortality, their causes and risk factor in rural Senegal. Methods : The study has been carried out in three rural sesttings under continuous demographic surveillance since several years. A total of 317, 110 and 44 deaths of women in reproductive age (15-44 years) has been recorded in Niakhar (1984-87), Bandafassi (1988-97) and Mlomp (1985-98), respectively. Information on each death has been summarised in a confidential verbal autopsy file. The maternal origin of the death, the obstetrical origin of maternal deaths and their essential cause have been independently attributed by two obstetricians and a medical epidemiologist. Maternal mortality measures were based on 87 maternal deaths in Niakhar, 33 in Bandafassi and 10 in Mlomp. A case-control study in Niakhar allowed to identify certain risk factors. Results : Almost a third of the deaths of the women in reproductive age was linked to a maternal cause. The maternal mortality ratio reached 852 deaths for 100,000 live births in Bandafassi, 516 in Niakhar and 436 in Mlomp. Almost two-thirds were directly related to pregnancy or delivery (direct obsteric deaths) and 10 % were indirect obstetric deaths. Haemorrhage was the leading cause of direct deaths and abortion the last frequent cause. A Young or old age, more than six pregnancies, history of abortion or still birth, delivery in a health facility and during the rainy season were identified as risk factors. Matrimonial status and antenatal care were not associated with maternal death. Conclusion : Maternal mortality remains high, although lower than WHO estimates for Senegal. The five main causes of maternal death were found. The role of malaria in maternal mortality should be more deeply investigated, particularly its role in eclampsia. The feasibility of confidential enquiries on maternal deaths has been demonstrated in Senegal
Ould, El Joud Dahada. "Epidémiologie des dystocies en Afrique de l'Ouest : incidence, facteurs de risque et prédictivité". Paris 11, 2001. http://www.theses.fr/2001PA11T027.
Objectives: (1) to measure the incidence of dystocia in 6 West African countries (6 cities and 1 rural area) (2) to identify risk factors of dystocia and study their interrelationships with the goal to potentially use them for the identification of high risk pregnant women during antenatal consultations (3) to assess their usefulness as predictors of dystocia during pregnancy (4) to study the consequences of dystocia, in particular uterine rupture (5) to suggest practical recommandations in view of reducing maternai mortality in West Africa. Methods: The MOMA study is a prospective population-based study that allowed the follow up of 20,326 West African pregnant women. The analysis of dystocia’s risk factors was done only on those deliveries performed in health facilities because of the likelyhood of diagnostic and recall biases in case of home deliveries. Overall, 16,318 deliveries have been analysed here. Uterine rupture was studied on all the deliveries (20. 326). Results: The incidence of dystocia in our study was 18. 3% [95% CI: 17,7-18,9]. After multivariate analysis (stepwise logistic regression), the significant risk factors were: short stature, scarred uterus and nulliparity. However, their positive predictive values were very low in univariate and multivariate analysis. One major consequence of dystocia: uterine rupture is studied. Conclusion: Dystocia, which occurs mainly during delivery, has a high incidence in West Africa. Its consequences are often dramatic, both for the fetus and the mother. No studied risk factor, even in combination, allowed to predict dystocia. Therefore, all pregnant women must be considered at risk of dystocia. Efforts should be put on the detection of dystocia during Jabor (partograph) and the quality of emergency obstetric care. Emergency obstetric care must be made available to all pregnant women. This goal is achievable in most major West African cities. The possibility of performing in good conditions C-sections must be increased even in rural areas. On the other hand, women with a scarred uterus must be told to deliver in a health facility with available and accessible emergency obstetric care
Hamdi, Leila. "Recherche de facteurs de risque immunologiques associés au Lymphome Hodgkinien de l'enfant". Phd thesis, Université Paris Sud - Paris XI, 2013. http://tel.archives-ouvertes.fr/tel-01011174.