Bibliografie tematiche / Drugs

Letteratura scientifica selezionata sul tema "Drugs"

Autore: Grafiati
Pubblicato: 4 giugno 2021
Ultima modifica: 29 luglio 2024

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Articoli di riviste sul tema "Drugs"

1

Khanapure, Amol, Pem Chuki e Avinash De Sousa. "Drug Repositioning : Old Drugs For New Indications". Indian Journal of Applied Research 4, n. 8 (1 ottobre 2011): 462–66. http://dx.doi.org/10.15373/2249555x/august2014/119.

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Bocharova, Inna Anatolevna, Vadim Agadzhanov e Vadim Sagalaev. "Drug addiction. Drugs and their effects on man". Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Serija 11. Estestvennye nauki, n. 2 (1 dicembre 2013): 22–27. http://dx.doi.org/10.15688/jvolsu11.2013.2.3.

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Isnenia, Isnenia. "Penggunaan Non-Steroid Antiinflamatory Drug dan Potensi Interaksi Obatnya Pada Pasien Muskuloskeletal". Pharmaceutical Journal of Indonesia 6, n. 1 (1 dicembre 2020): 47–55. http://dx.doi.org/10.21776/ub.pji.2020.006.01.8.

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The main therapy on musculoskeletal patients is the use of non-steroidal anti-inflammatory drugs (NSAIDs) either as monotherapy or in combination with drugs of the same class or pain relievers from other groups. The use of more than one drugs have potentially caused drug-drug interactions that can affect to patient. This study was aimed to describe the patient's sociodemographic (sex, ages) and clinical (numbers of drugs, type of drugs and diagnose) characteristics, as well as to find the correlation between potential drug interactions with these variables. This research was a quantitative study with a cross sectional design. Data were taken from 100 medical records of patients who had diagnosed with top five musculoskeletal diseases. Data were analyzed descriptively for sex, ages, number of drugs, type of drugs, and potential drug interactions. Bivariate correlation with chi-square were conducted to find statistically significancy potential drug interactions with each variable consist of sex, ages, type of drugs and it’s diagnose. The result shows that the musculoskeletal patients were 44% male, 56% female. Most musculoskeletal patients were aged 18-65 years (78%). Patients who received drugs <5 were 68% and ≥ 5 were 32%. 54% of patients were taking the diclofenac and only 5% of patients were taking the two NSAIDs combination, diclofenac and ibuprofen. There was no significant correlation (p > 0,05) between potential drug interactions with age, sex, type of NSAID, and type of musculosceletal diseases.
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Renner, Rebecca. "Drams of Drugs and Dregs". Scientific American 286, n. 5 (maggio 2002): 29. http://dx.doi.org/10.1038/scientificamerican0502-29.

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Ismatov, Farrukh Asliddinovich. "DRUG TREATMENT WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS JAW ALVEOLITIS". Frontline Medical Sciences and Pharmaceutical Journal 02, n. 03 (1 marzo 2022): 88–94. http://dx.doi.org/10.37547/medical-fmspj-02-03-09.

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Non-steroidal anti-inflammatory drugs are widely used to suppress inflammation in the body. NSAIDs are available in different forms: tablets, capsules, ointments. They have three main properties: antipyretic, anti-inflammatory and analgesic. The best non-steroidal anti-inflammatory drug can only be chosen by a doctor, based on the individual characteristics of the patient. Self-treatment in this case may be fraught with serious adverse reactions or overdose. We suggest reading the list of drugs. The rating is based on value for money, patient feedback and expert opinion.
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A. Amer, Sayed. "المخدرات الجديدة: العقاقير المصممة". Security Policy Paper 2, n. 2 (31 dicembre 2021): 01–03. http://dx.doi.org/10.26735/ndan7653.

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D, Subba Reddy, Prasanthi G, Amruth Raj S, Hari Krishna T, Sowjanya K e Shantha Kumari K. "EVALUATION OF ANTICANCER GENERIC DRUGS AND BRANDED DRUGS". Indian Research Journal of Pharmacy and Science 5, n. 1 (marzo 2018): 1378–91. http://dx.doi.org/10.21276/irjps.2018.5.1.16.

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Khrypunova, Tetiana. "Relationships between the Ukrainian Public's Awareness of Psychotropic Drugs, Stigmatizing People Taking Psychotropic Drugs and Stopping Psychotropic Drug Medication without Consulting with a Doctor". Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6, n. 5 (27 ottobre 2021): 370–75. http://dx.doi.org/10.26693/jmbs06.05.370.

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The purpose of the study was to outline possible relationships between public awareness of psychotropic drugs, stigmatization of people suffering from mental disorders and discontinuation of drugs without consultation with a doctor in Ukraine. Materials and methods. This study is based on the analysis of data obtained through an electronic questionnaire filled out by the Ukrainian public. Until April 2021 the questionnaire was freely available to everyone who wanted to take part in the survey. The questionnaire was distributed via an Internet link. Based on the obtained data, the respondents were divided into different categories depending on their education, profession (a medical worker was analyzed separately). Also, the respondents who had personal experience of using psychotropic drugs were interviewed especially deeply and in more details, depending on which group of drugs they used (antidepressants / antipsychotics / anxiolytics). The separate place in the study was given to identifying the general awareness of the Ukrainian public about correct and erroneous judgments about psychotropic drugs. Results and discussion. Based on the obtained data, main factors which are influencing people awareness of psychotropic drugs were identified, as well as the approximate percentage of citizens with erroneous judgments about psychotropic drugs. Thanks to the results of the questionnaire, the main possible reasons for the withdrawal of treatment with psychotropic drugs by patients without consultation with the attending physician were suggested (identified). Conclusion. It can be concluded from the obtained data that a person's awareness in the field of psychotropic drugs is most influenced by their own experience of their use. For this reason, the author would be interested to know how psychiatric patients are informed by their physicians. The author is aware that the amount of data obtained is not completely sufficient to create a significant picture of the general situation, but she hopes that the obtained data will still allow to get some idea of the situation as a whole. In conclusion, not only the obtained results in this study were outlined, but also possible further actions to obtain a more accurate picture of the situation were mentioned, and the topic of the next study was indicated in order to solve the identified problem
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Gillam, Tony. "Drugs or no drugs?" Nursing Standard 20, n. 23 (15 febbraio 2006): 26–27. http://dx.doi.org/10.7748/ns.20.23.26.s30.

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Chawra, Himmat Singh, Y. S. Tanwar, Ritu M. Gilhotra e S. K. Singh. "Gastroretentive drug delivery systems a potential approach for antihypertensive drugs: An updated review". Asian Pacific Journal of Health Sciences 5, n. 2 (giugno 2018): 217–23. http://dx.doi.org/10.21276/apjhs.2018.5.2.40.

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Tesi sul tema "Drugs"

1

Keesling, James Richard. "An evaluation of the drugs crime nexus, legalization of drugs, drug enforcement, and drug treatment rehabilitation". CSUSB ScholarWorks, 2000. https://scholarworks.lib.csusb.edu/etd-project/1697.

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Law enforcement agencies are faced with the problem of how to reduce crime in the most economical method possible without violating the law. Since drug offenders also engage in a disproportionate amount of non-drug crime, then drug enforcement is considered as an acceptable general crime control method. Unfortuantely, this is an expensive option because incarcerating offenders is both costly and ony a short-term solution to the problem. A review of existing research examining the prior criminal histories of drug offenders compared to their previous involvement in violent and property crime is conducted to evaluate this relationship.
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Apps, MIchael Garry. "Platinum anticancer drugs and drug delivery systems". Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14409.

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In this thesis two different ways to improve platinum-based chemotherapy were investigated. The first was through the use of a new slow release clay-based drug delivery vehicle and the second through the design and synthesis of novel dinuclear platinum complexes. For the clay-based drug delivery research, the platinum anticancer complex [(1,10-phenanthroline)(1S,2S-diaminocyclohexane)platinum(II)] chloride, PHENSS, was loaded into montmorillonite (MMT) clay. The PHENSS was found to be incompletely burst released from the MMT. The MMT also had a negative effect on the in vitro cytotoxicity of PHENSS in the human breast cancer cell lines MCF-7 and MDA-MB-231. Overall the results demonstrate that MMT is not a suitable slow release vehicle for PHENSS. For the dinuclear platinum complex synthesis research, new bispyridine-based bridging ligands were synthesised using an amide coupling reaction. The bridging ligands were then reacted with transplatin to yield the dinuclear platinum complexes. The platinum complexes have potential application as anticancer agents and the synthetic method can be modified to produce other multinuclear complexes.
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Osorio, Javier. "Hobbes on drugs| Understanding drug violence in Mexico". Thesis, University of Notre Dame, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3738644.

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This dissertation analyzes the unprecedented eruption of organized criminal violence in Mexico. To understand the dynamics of drug violence, this dissertation addresses three questions. What explains the onset of the war on drugs in Mexico? Once the conflict starts, why does drug violence escalate so rapidly? And lastly, why is there subnational variation in the concentration of violence?

Based on a game theoretic model, the central argument indicates that democratization erodes the peaceful configurations between the state and criminal organizations and motivates authorities to fight crime, thus triggering a wave of violence between the state and organized criminals and among rival criminal groups fighting to control strategic territories. In this account, state action is not neutral: law enforcement against a criminal group generates the opportunity for a rival criminal organization to invade its territory, thus leading to violent interactions among rival criminal groups. These dynamics of violence tend to concentrate in territories favorable for the reception, production and distribution of drugs. In this way, the disrupting effect of law enforcement unleashes a massive wave of violence of all-against-all resembling a Hobbesian state of war.

To test the observable implications of the theory, the empirical assessment relies on a novel database of geo-referenced daily event data at municipal level providing detailed information on who did what to whom, when and where in the Mexican war on drugs. This database covers all municipalities of the country between 2000 and 2010, thus comprising about 9.8 million observations. The creation of this fine-grained database required the development of Eventus ID, a novel software for automated coding of event data from text in Spanish. The statistical assessment relies on quasi-experimental identification strategies and time-series analysis to overcome problems of causal inference associated with analyzing the distinct - yet overlapping - processes of violence between government authorities and organized criminals and among rival criminal groups. In addition, the statistical analysis is complemented with insights from fieldwork and historical process tracing. Results provide strong support for the empirical implications derived from the theoretical model.

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Hernández, Yulán. "Drugs". Revista de Química, 2016. http://repositorio.pucp.edu.pe/index/handle/123456789/101299.

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Dossou-Yovo, Flore. "Modification de la biodisponibilité orale des médicaments : interactions « Herb-Drugs » « Drugs- Drugs»". Thesis, Paris, CNAM, 2014. http://www.theses.fr/2014CNAM0936/document.

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L’administration par voie orale des médicaments reste encore de nos jours la voie royale de la prise des médicaments car moins onéreuse et plus adaptée au confort du patient. Mais cette voie reste toujours inaccessible pour certains médicaments comme les médicaments biologiques et les bio similaires voir certains anticancéreux et antirétroviraux.Le but de ce travail est d’améliorer la biodisponibilité par voie orale des médicaments à faible biodisponibilité par la mise au point d’un promoteur d’absorption. Pour y arriver nous avons adopté comme stratégie de développer un promoteur qui agit à la fois sur le passage passif et sur le passage actif des médicaments. Les études in vitro ont été réalisées en chambre de perméation d’Ussing adaptées par la société Biomécatronics SAS (BéthuneFrance). Dans la première partie de ce travail (Brevet), nous avons montré que l’utilisation d’une composition pharmaceutique et/ou diététique comprenant un extrait de plante(Hibiscus sabdariffa) pouvait augmenter la biodisponibilité in vitro des médicaments et des xénobiotiques qui passent par la voie paracellulaire comme le cisplatine (21 fois),l’oxaliplatine (11fois), la fluorescéine isothiocyanate-Dextran 4000 (3 fois), mais également les médicaments connus pour leur transport actif par la voie transcellulaire comme l’Efavirenz (7 fois) et l’Atazanavir (4 fois). Dans la seconde partie de ce travail, nous avons cherché à vérifier si notre promoteur d’absorption des médicaments a un effet sur la couche de mucus intestinale.Cette couche peut être un facteur limitant de passage des médicaments au travers de la barrière intestinale.Dans un premier temps (article 1), nous avons induit l’augmentation de la couche mucus au niveau du colon de rat après un prétraitement pendant une semaine avec le métronidazole. Puis nous avions confirmé (article 2) que l’administration par voie orale de deux antibiotiques le Cotrimoxazole (CTX) et le métronidazole (MTZ) pendant une semaine augmente la couche de mucus au niveau du côlon ; aussi nous avons montré qu’il existe une relation entre l’augmentation de la couche de mucus et la diminution de la conductance qui est l’index de transport passif des ions, des électrolytes et de certaines molécules à faibles poids moléculaires.De plus l’augmentation de la couche de mucus au niveau de l’intestin est responsable de la diminution du passage transépithélial des deux antirétroviraux dont l’utilisation est recommandée en première ligne par l’OMS (le.Ritonavir et l’Atazanavir) surles sujets porteurs du VIH (virus de l’immunodéficience humain). Après les traitements auMTZ et au CTX la sécrétion de l’Atazanavir augmente respectivement dans le côlon proximal de 2 et 4 fois et dans le côlon distal de 3 et 5 fois. On obtient également une sécrétion du Ritonavir de 5 et 10 fois dans le proximal et de 2 et 5 fois plus dans le distal.Le travail se poursuit par l’étude de l’effet de notre promoteur d’absorption des médicaments sur la couche de mucus intestinal.En conclusion, ce travail montre que l’on peut augmenter la biodisponibilité in vitroen utilisant les promoteurs de l’absorption des xénobiotiques qui agissent à la fois au niveau du transport passif et actif
Oral dosing is still seen as the silver bullet of drug administration, as it is cheaper andbetter adapted to patient comfort. However, oral route is still inaccessible to many drugssuch as biologics and biosimilars respectively certain anticancer drugs and antiretrovirals(ARV).The aim of this present study was to find new drugs enhancers that improve the oralbioavailability of drugs and xenobiotics. All the studies were realized in vitro using Ussingchambers technic. To achieve the set objective we used the strategy to develop drugenhancer which can modulate at the same time transcellular and paracellular pathways.In the first part of this study (patent) we have shown that the use of a pharmaceutical and /or a dietetic formulation containing a plant extract (Hibiscus sabdariffa) could increase thebioavailability in vitro in rats not only of cisplatin (21 fold), oxaliplatin (11 fold) andFluorescein Isothiocyanate-Dextran 4000 (FD4, 3 fold). All that drugs were transportedthrough intestinal barrier using paracellular pathway. In addition the study showed thatthis formulated enhancer can increased the bioavailability of Efavirenz (7 fold) andAtazanavir (4 fold) which are active transported.In order to assess the effect of new drugs enhancer on mucus thickness that limits thetransport of xenobiotic through intestinal barrier, we decide to evaluate his effect on passiveand active transport of drugs.In the second part of this study we have shown that after a week of pre-treatment of ratswith Metronidazole (MTZ, publication 1) and Cotrimoxazole (CTX, publication 2), the twomost commonly used antibiotics in the prophylaxis against opportunistic infections in HIV /AIDS, both increase colonic mucus thickness that affect directly passive intestinalpermeability by reducing conductance an index of passive transport through intestinalepithelium. In addition those antibiotics also entail a change in the transepithelialconductance and ARV fluxes. After MTZ and CTX treatment the secretion of Atazanavir(ATZ) increases respectively in the proximal colon by 2 to 4 fold and in the distal colon by 3to 5 fold respectively. Ritonavir (RTV) is poorly absorbed in control, after a week of pretreatmentwith MTZ and CTX one rather notices a secretion of RTV 5 to 10 fold higher in theproximal and 2 to 5 fold higher in the distal colon. The next study will be conducted toevaluate the effect of new drugs enhancer on mucus thickness layer.In conclusion, oral bioavailability of drugs and xenobiotics can be enhanced bypharmaceutical composition that contains herbal extract which increase passive and activetransport of drugs through intestinal barrier
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Mohiddin, Syed Basha. "Development of novel unsupervised and supervised informatics methods for drug discovery applications". Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1138385657.

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Rosenbaum, Erik. "Optical characterization of potential drugs and drug delivery systems". Doctoral thesis, Umeå universitet, Kemiska institutionen, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-40177.

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This Thesis is a characterization study on substances having potency as drugs as well as on a lipid based drug-delivery matrix. The optical properties of newly synthesized molecules with proven pilicide properties have been characterized with several spectroscopic methods. These methods include optical absorption and fluorescence as well as time-resolved fluorescence. Upon covalently linking compounds with high quantum yields of fluorescence to specific parts of the pilicide, the biological impact was found to increase for some of the derivatives. Furthermore, by expanding the aromatic part of the pilicide molecule, a significant increase in the inherent fluorescence was obtained. The S0-S1 absorption band for these molecules was found to originate from an impure electronic transition, vibronically promoted by intensity borrowing from higher electronic states. Included in this Thesis is the measurement of how deeply some in this class of newly synthesized molecules become situated when placed inside ganglioside GM1 micelles, and how the molecules’ reorientation is affected. By means of radiation-less energy transfer, it was shown that the molecules place themselves close to the hydrophobic-hydrophilic interface inside the GM1 micelles. As a consequence they are exposed to a densely packed environment, which inhibits the free tumbling of the molecule. This restricted tumbling could be measured by means of time-resolved depolarization experiments. The release of drug-like fluorescent molecules is investigated from a lipid mixture, which upon equilibrium with water forms a mixture of inverted hexagonal and cubic phases. The lipid matrix displayed an extended release over the course of weeks, in vitro, for molecules having a large variation in hydrophobicity.
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Attardo, Giorgio G. (Giorgio Giovanni). "Drug design and synthesis of novel heteroanthracycline antitumor drugs". Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74641.

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Novel heteroanthracycline antitumor drugs were designed based on structure activity relationship studies and known mechanisms of drug action. Their preparation required the development of a general synthetic approach.
After extensive studies, three methodologies were developed for the general synthetic plan. The first method involved photoenolisation of 2,5-dimethoxybenzaldehyde and SO$ sb2$ entrapment of the o-quinodimethane to give 4,7-dimethoxy-1-hydroxy-1,3-dihydrobenzo(2,3-c) thiophene-2,2-dioxide. This compound served as a general intermediate towards the synthesis of several heteroanthracyclinones. It could be reduced to the oxathiin-2-oxide derivative which thermally extruded SO$ sb2$ to yield the o-quinodimethane. Reentrapment of this latter intermediate with various glyoxalates gave key isochroman derivatives. The second method is an improvement over the first. Isochromandiones with a C-1 hydroxyl functionality were prepared from oxidative demethylation of 1-hydroxyisochromans. These were obtained after acid hydrolysis of the coupling products between epoxides and the cuprate of 2,5-dimethoxy-6-methylbenzaldehydedioxane acetal. The third method involved a sequential cycloaddition routine with two o-quinodimethanes.
By combining newly developed techniques with known methods, a general synthetic plan was developed. Consequently, the total synthesis of six tetracyclic structural hybrids of the naphthoquinone(2,3-c) pyranyl class of antibiotics was accomplished; along with the total synthesis of (R) and (S) 1-(4$ sp prime$-O-p-nitrobenzoyl-N-trifluoroacetyldaunosamine)-$ 1,3$-dihydrothioxantho(2,3-c) thiophene-2,2-dioxide, p-nitrobenzyl(5,12-dihydroxy-3,4-dihydrothioxantho(2,3-c) and (3,2-c) pyran-3-yl)formate, and eight novel heteroanthracyclines with the 5,12-dioxo-2,3,5,12-tetrahydroanthraceno(2,3-c) pyranyl backbone. The diastereomeric mixture of (1$ sp prime$S, 1R, 3S) and (1$ sp prime$S, 1S, 3R) methyl(11-hydroxy-1-$(2 sp prime,3 sp prime,6 sp prime $-trideoxy-3-trifluoroacetamido-L-lyxohexopyranose)-$5,12 $-dioxo-3,4,5,12-tetrahydroanthraceno(2,3-c) pyran-3-yl) formate was found to possess equipotent antileukemic activity to doxorubicin with no cross resistance.
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Hill, John C. "DRUMMING AWAY DRUGS: AN INNOVATIVE ALTERNATIVE TOWARDS DRUG REHABILITATION". UKnowledge, 2014. http://uknowledge.uky.edu/cld_etds/14.

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Drug use poses a serious threat to the quality of life for many Kentuckians and their families. Recent statistics indicate drug offenders account for a significant portion (in one year, 52,597 arrests were made for drug violations statewide) of individuals within thecriminal justice system, directly affecting the economic vitality within our state (Bunn & Slavova, 2012; Federal Bureau of Investigation, 2012). These statistics signify an overwhelming need for effective prevention efforts and innovative treatment alternatives. This study provides an innovative alternative treatment for drug offenders that infuses social and emotional coping strategies using percussion as a context. During the innovative program participants were able to express, recognize, articulate and evaluate themselves and their peers’ emotional coping strategies while developing peer camaraderie. They did so while being introduced to rudimentary drumming skills, fusing emotional intelligence with the art of drumming. The hypothesis is that this innovative program will enhance participant emotional intelligence to express, learn an effective coping skill, and establish camaraderie with their peers.
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Hemingway, Judith Frances Mary. "Spatializing drugs discourses : cultural geographies of illicit drug-using". Thesis, University College London (University of London), 2003. http://discovery.ucl.ac.uk/10020432/.

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Libri sul tema "Drugs"

1

Ward, Brian R. Drugs and drug abuse. London: F. Watts, 1987.

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Ward, Brian. Drugs and drug abuse. London: Watts, 1987.

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1946-, Stangeland Per, a cura di. Drugs and drug control. Oslo: Norwegian University Press, 1987.

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Ottenbrite, Raphael M., a cura di. Polymeric Drugs and Drug Administration. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/bk-1994-0545.

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M, Ottenbrite Raphael, e Kim Sung Wan, a cura di. Polymeric drugs & drug delivery systems. Lancaster, Pa: Technomic Pub. Co., 2001.

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Group, Publishers, a cura di. Street drugs: Drug identification guide. Plymouth, MN: Publishers Group, 2007.

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Group, Publishers, a cura di. Street drugs: Drug identification guide. [Plymouth, MN]: Publishers Group, 2002.

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Massachusetts. Department of Public Health. Generic drugs (interchangeable drugs). Boston, MA: Massachusetts Dept. of Public Health, 1988.

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Owen, Claire. Drugs. Cambridge: Independence, 2009.

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Police, Illinois State. Drugs. Springfield, Ill.]: Illinois State Troopers, Dept. of State Police, 1986.

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Capitoli di libri sul tema "Drugs"

1

Eleonorasdotter, Emma. "Obtaining Drugs". In Women’s Drug Use in Everyday Life, 143–73. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-46057-9_5.

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AbstractThis chapter, like the last one, deals with encounters between drugs and people. Here, the focus is on how the women acquire drugs in relation to drug markets. The clash between an illegal, masculine-coded street market associated with violence, and the ideal drug-induced state that is described in terms of intimacy and community, is explored. Where does the encounter between the women and the drugs they use take place? On what terms? What are the roles of gender and class? Some women buy their drugs themselves, but many receive most of their drugs as gifts. In the latter case, drugs move into a gift economy that involves different forms of expectation of reciprocation in various different, classed contexts.
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Folkers, Gerd, Elvan Kut e Martin Boyer. "Drug Design: Designer Drugs". In X.media.publishing, 53–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-69002-3_5.

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Barber, James G. "Drugs and Drug Addiction". In Social Work with Addictions, 1–25. London: Macmillan Education UK, 1995. http://dx.doi.org/10.1007/978-1-349-23805-7_1.

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Harris, Howard A., e Henry C. Lee. "Drugs and drug analysis". In Introduction to Forensic Science and Criminalistics, 327–56. Second edition. | Boca Raton, FL : CRC Press, [2019] | Revised edition of : Introduction to forensics & criminalistics / Howard A. Harris, Henry Lee, c2008.: CRC Press, 2019. http://dx.doi.org/10.4324/9781315119175-13.

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Mishra, Soni, e Abhishek Kumar Mishra. "Drugs, Drug–Biomolecule Interactions, and Drugs Delivery Systems". In Computational Studies, 53–67. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003441328-4.

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Hartman, David E. "Drugs". In Critical Issues in Neuropsychology, 267–325. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1849-5_6.

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Law, Simon K. "Drugs". In Risk Prevention in Ophthalmology, 131–47. New York, NY: Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-73341-8_13.

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De Castro, J., J. Meynadier e M. Zenz. "Drugs". In Regional Opioid Analgesia, 131–209. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-009-2321-8_8.

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Broad, John. "Drugs". In Science and Criminal Detection, 15–32. London: Macmillan Education UK, 1988. http://dx.doi.org/10.1007/978-1-349-10604-2_2.

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McMullin, Tami S. "Drugs". In Physiologically Based Pharmacokinetic Modeling, 271–96. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471478768.ch10.

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Atti di convegni sul tema "Drugs"

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Amer, Samar A., e Sami I. Almudarra. "Assessment of Drug Use Pattern among Hajj Pilgrims Saudi Arabia, 1439h (2018)". In 2nd International Conference on Public Health and Well-being. iConferences (Pvt) Ltd, 2022. http://dx.doi.org/10.32789/publichealth.2021.1009.

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Hajj pilgrimage is the biggest and longest mass gathering, thus increasing the risk of communicable and non-communicable diseases, so this study aimed to promote rational drug use and optimum provision of drugs among Hajj 1439 Pilgrims through the following objectives: To determine the prevalence and the context of the drug's use and to assess the drug use patterns among pilgrims. METHODS: A cross-sectional study was carried out on randomly selected 785 Hajj Pilgrims, stratified according to their countries before their retrial in King Abdul Aziz Airport in Jeddah: The studied pilgrims were 52.4 % male,43.9% had chronic diseases, only 70.4% of studied pilgrims received medications, most of them were antibiotics 248 (33.8%), administrated orally 470 (90.6%), for managing chronic diseases 341 (61.66%), only 50% had written prescription. Patient care indicators; more than 80% of pilgrims knowing the drug/s correct dose, and 69.4 knowing the expired date. Facility indicators; 77% of studied pilgrims reported accessibility of medications, and only 12.4% of the bought drugs had been checked, and 20.3% complained of drug side effects mainly due to drugs unavailability. Conclusions; the drug use pattern is a prevalent and problematic issue among pilgrims due to many factors.
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Li, Kun, Weiwei Liu, Yong Luo, Xiantao Cai, Jia Wu e Wenbin Hu. "Zero-shot Learning for Preclinical Drug Screening". In Thirty-Third International Joint Conference on Artificial Intelligence {IJCAI-24}. California: International Joint Conferences on Artificial Intelligence Organization, 2024. http://dx.doi.org/10.24963/ijcai.2024/234.

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Conventional deep learning methods typically employ supervised learning for drug response prediction (DRP). This entails dependence on labeled response data from drugs for model training. However, practical applications in the preclinical drug screening phase demand that DRP models predict responses for novel compounds, often with unknown drug responses. This presents a challenge, rendering supervised deep learning methods unsuitable for such scenarios. In this paper, we propose a zero-shot learning solution for the DRP task in preclinical drug screening. Specifically, we propose a Multi-branch Multi-Source Domain Adaptation Test Enhancement Plug-in, called MSDA. MSDA can be seamlessly integrated with conventional DRP methods, learning invariant features from the prior response data of similar drugs to enhance real-time predictions of unlabeled compounds. The results of experiments on two large drug response datasets showed that MSDA efficiently predicts drug responses for novel compounds, leading to a general performance improvement of 5-10% in the preclinical drug screening phase. The significance of this solution resides in its potential to accelerate the drug discovery process, improve drug candidate assessment, and facilitate the success of drug discovery. The code is available at https://github.com/DrugD/MSDA.
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Suryakrishna, S. S., K. Praveen, S. Tamilselvan e S. Srinath. "IoT Based Automation and Blockchain for Medical Drug Storage and Smart Drug Store". In Intelligent Computing and Technologies Conference. AIJR Publisher, 2021. http://dx.doi.org/10.21467/proceedings.115.8.

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The increase in the work stress and decrease in the time for oneself has led to the rise in the dependency on the medicines and drugs. The drugs and medicines are the key sources for saving the human life when the patient is in the danger. In order to maintain regular and quality supply of the drugs and medicines has to monitor on the regular basis. There are numerous medicines and drugs brought in the store but usually drugs and medicines are stolen to satisfy one’s greed, get expired or placed at unknown locations in the store. So to prevent such situation and saving the life of the patient Drug and Medicine Monitoring Model can be used. The model uses the RFID and IoT technology in order to monitor the drugs and medicines in the store. In medical and drug using systems which are increasing work stress and decreasing the time for oneself that has risen in dependency. The danger situation drugs and medicine is the main source for saving human life when the people are in danger. A daily regular basis to maintain a quality supply of the drug and medicine has been monitored. While traveling and transportation time is numerous medicines and drugs brought from the store but usually it is stolen to one’s greed and the medicines and drugs or placed at unknown locations. To prevent and save a patent life and monitoring model can be used to check the medicine and drug. In our model RFID tag and IoT technology can be used to monitor medicine and drug storage with the help of hospitals and how having a knowledge of the system and chemist of the medical and drugs available, the medicines and drugs quality of location and their safety.
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Kathawate, Jyoti, e Sumanta Acharya. "Computational Modeling of Intravitrael Drug Delivery in the Vitreous Chamber With Vitreous Substitutes". In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72783.

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Effective treatment of posterior segment diseases depends on the ability to deliver appropriate doses of drugs to target tissues in the posterior chamber of the eye. Intravitreal injection of drug is commonly used to treat vitreoretinal diseases. In order to assess the effectiveness of the injected drug, it is critical to know the drug distribution within the eye following injection. This is particularly important when the vitreous has been replaced by substitutes since there is little understanding of the transport of drugs in vitreous substitutes. The main objective of this research is therefore to characterize the drug distribution following intravitreal injection in the vitreous chamber of the human eye with different vitreous substitutes. In the present study, different intravitreal substitutes like silicone oil, fluorosilicone oil and perfluorocarbon liquids are considered. Both direct injection of drugs and injection of a time released drug distribution are studied. The results show that the concentration distribution is highly dependent on the vitreous substitute and the diffusion coefficient of the drug. For drugs with high diffusion coefficients, convection plays a small role. For drugs with low diffusion coefficients and for vitreous fluids with low viscosity, convection is seen to play a more important role.
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KOMARAGIRI, RAJESH. "Recycling of Drugs from Expired Drug Products". In 1st International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2016. http://dx.doi.org/10.3390/ecmc-1-a003.

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KOMARAGIRI, RAJESH. "Recycling of Drugs from Expired Drug Products". In 1st International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a005.

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KADHIM, Shafq, Osama Q. FADHIL, Zahraa SAAD e Dhafir QAHTAN. "SAFETY AND MISUSE OF PRESCRIBED MEDICATIONS DURING PREGNANCY". In VI.International Scientific Congress of Pure,Applied and Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress6-15.

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The unique nature and physiology of pregnancy represents a challenge for choosing suitable, efficacious and safe drug therapy. Pharmacokinetic of medicines is very complicated during pregnancy as many important physiological changes happen during this period. FDA classifies medicines used in pregnancy into five categories A, B, C, D and X. Category A is considered the safest category while X is absolutely contraindicated in pregnancy. This a descriptive cross-sectional study aimed to demonstrate safety of prescribed drugs and the extent of drug misuse during pregnancy. The results demonstrated that 82% of prescriptions lack the full scientific information and 75% of prescriptions containing drugs fall within C and D categories. Moreover, the results showed that 29% of drugs are category C (most commonly prescribed drug was hyoscin butylbromide), and 14% of drugs are category D (most commonly prescribed drug was phenoparbiton). A high percentage of prescriptions was seen with multiple items that can increase the associated side effects and about 22 % of prescriptions were refilled many times and more than half of this percentage used them without medical consultations; this indicates that many pregnant women may misuse these drugs. From this study we concluded that there is a misuse of medicines during pregnancy and a high percentage of pregnant women have used unsafe medications. Therefore prescribing drugs during this period needs a special care as this issue can be dangerous for mother and her fetus.
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Kurtoğlu, Gazi Levent. "Anti-Drug Supply Policies: Inter-institutional Coordination and Action Plans". In Panel on "Effective Drug Control Strategies in Northern Cyprus: Challenges and Opportunities in 2024". Emanate Publishing House Ltd., 2024. http://dx.doi.org/10.70020/ehass.2024.7.6.

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Türkiye has been developing strategic plans and related action plans to fight addictions including drugs since 2006. The responsibility for nationwide coordination is under the jurisdiction of the Department of Combating Tobacco and Substance Addiction in the Ministry of Health. This paper focuses on four research objectives: firstly, the inter-institutional coordination mechanisms in place for combating drug supply in Türkiye; secondly, the National Strategy Documents and Action Plans in the fight against drugs developed and implemented so far in Türkiye; and thirdly, the contents of the Action Plans the fight against drugs in Türkiye between 2006-2023 are presented. The fourth research objective covers noteworthy literature review on strategies to ensure the fight against drug supplies in Türkiye’s Action Plan are compatible with those of the EU Drugs Strategy and Action Plan. The paper concludes with recommendations for the coordination of the fight against drug supply in the Strategy and Action Plan for Northern Cyprus.
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Khamenehfar, Avid, Ji Liu, Jia Cai, Michael Wong, Paul C. H. Li, Patrick Ling e Pamela Russell. "Drug Accumulation Into Single Drug-Sensitive and Drug-Resistant Prostate Cancer Cells Conducted on the Single Cell Bioanalyzer". In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-36166.

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Multidrug resistance (MDR) occurs in prostate cancer, and this happens when the cancer cells resist chemotherapeutic drugs by pumping them out of the cells. MDR inhibitors such as cyclosporin A (CsA) can stop the pumping and enhance the drugs accumulated in the cells. The cellular drug accumulation is monitored using a microfluidic chip mounted on a single cell bioanalyzer. This equipment has been developed to measure accumulation of drugs such as doxorubicin (DOX) and fluorescently labeled paclitaxel (PTX) in single prostate cancer cells. The inhibition of drug efflux on the same prostate cell was examined in drug-sensitive and drug-resistant cells. Accumulation of these drug molecules was not found in the MDR cells, PC-3 RX-DT2R cells. Enhanced drug accumulation was observed only after treating the MDR cell in the presence of 5 μM of CsA as the MDR inhibitor. We envision this monitoring of the accumulation of fluorescent molecules (drug or fluorescent molecules), if conducted on single patient cancer cells, can provide information for clinical monitoring of patients undergoing chemotherapy in the future.
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Celebi, Remzi, Vahab Mostafapour, Erkan Yasar, Ozgur Gumus e Oguz Dikenelli. "Prediction of Drug-Drug Interactions Using Pharmacological Similarities of Drugs". In 2015 26th International Workshop on Database and Expert Systems Applications (DEXA). IEEE, 2015. http://dx.doi.org/10.1109/dexa.2015.23.

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Rapporti di organizzazioni sul tema "Drugs"

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Ciapponi, Agustín. What are the effects of reference pricing and other pharmaceutical pricing and purchasing policies? SUPPORT, 2016. http://dx.doi.org/10.30846/1608143.

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Pharmaceutical pricing and purchasing policies are used to determine or affect the prices that are paid for drugs. This review found evidence for reference pricing, index pricing, and maximum prices. In reference pricing a reference drug is chosen amongst identical or similar medicines or therapeutically equivalent and the price of the reference drug is reimbursed for all the drugs in that group of drugs. For drugs that are more expensive than the reference drug, the patient has to pay the cost above the reference price. An index price is the maximum refundable price to pharmacies for drugs within an index group of therapeutically interchangeable drugs. A maximum price is a fixed price that attempts to secure pharmaceutical prices that are considered ‘reasonable’ for a given health system.
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Fadlallah, Racha, Fadi El-Jardali e Elie Akl. Which interventions are effective in combatting or preventing drug counterfeiting? SUPPORT, 2017. http://dx.doi.org/10.30846/170517.

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Drug counterfeiting is widespread globally, including in low- and middle-income countries. Counterfeit medicines may include medicines with the wrong ingredients, without active ingredients, with insufficient active ingredients or with fake packaging. Counterfeit drugs need to be distinguished from substandard drugs - the latter refers to genuine medicines that failed to meet certain quality specifications. Interventions to combat drug counterfeiting can broadly be categorized into laws and regulations, technological innovations and quality control and vigilance.
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Lim, Peter. Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulation. Fort Belvoir, VA: Defense Technical Information Center, novembre 2010. http://dx.doi.org/10.21236/ada536829.

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Lim, Peter. Analytical and Characteristics Studies of Organic Chemicals, Drugs, and Drug Formulations. Fort Belvoir, VA: Defense Technical Information Center, novembre 2012. http://dx.doi.org/10.21236/ada567567.

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Lim, Peter. Analytical and Characterization Studies of Organic Chemicals, Drugs and Drug Formulation. Fort Belvoir, VA: Defense Technical Information Center, febbraio 2004. http://dx.doi.org/10.21236/ada421361.

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Lim, Peter, e Lori Olson. Analytical and Characterization Studies of Organic Chemicals, Drugs and Drug Formulation. Fort Belvoir, VA: Defense Technical Information Center, luglio 1998. http://dx.doi.org/10.21236/ada352491.

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Lim, Peter. Analytical and Characterization Studies of Organic Chemicals, Drugs and Drug Formulations. Fort Belvoir, VA: Defense Technical Information Center, ottobre 2006. http://dx.doi.org/10.21236/ada466154.

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Lim, Peter. Analytical and Characterization Studies of Organic Chemicals, Drugs and Drug Formulations. Fort Belvoir, VA: Defense Technical Information Center, ottobre 2005. http://dx.doi.org/10.21236/ada466189.

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Lim, Peter. Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulation. Fort Belvoir, VA: Defense Technical Information Center, novembre 2011. http://dx.doi.org/10.21236/ada554000.

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Lim, Peter. Analytical, Characterization, and Stability Studies of Organic Chemical, Drugs, and Drug Formulation. Fort Belvoir, VA: Defense Technical Information Center, maggio 2014. http://dx.doi.org/10.21236/ada601351.

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