Articoli di riviste sul tema "Dihydroxypyrimidines"
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Powdrill, Megan H., Jerome Deval, Frank Narjes, Raffaele De Francesco e Matthias Götte. "Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines". Antimicrobial Agents and Chemotherapy 54, n. 3 (22 dicembre 2009): 977–83. http://dx.doi.org/10.1128/aac.01216-09.
Guo, Di-Liang, Xing-Jie Zhang, Rui-Rui Wang, Yu Zhou, Zeng Li, Jin-Yi Xu, Kai-Xian Chen, Yong-Tang Zheng e Hong Liu. "Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity". Bioorganic & Medicinal Chemistry Letters 22, n. 23 (dicembre 2012): 7114–18. http://dx.doi.org/10.1016/j.bmcl.2012.09.070.
Novais, H. M., e S. Steenken. "Reactions of oxidizing radicals with 4,6-dihydroxypyrimidines as model compounds for uracil, thymine, and cytosine". Journal of Physical Chemistry 91, n. 2 (gennaio 1987): 426–33. http://dx.doi.org/10.1021/j100286a034.
Telvekar, Vikas N., e Kavitkumar N. Patel. "Pharmacophore Development and Docking Studies of the HIV-1 Integrase Inhibitors Derived from N-methylpyrimidones, Dihydroxypyrimidines, and Bicyclic Pyrimidinones". Chemical Biology & Drug Design 78, n. 1 (25 maggio 2011): 150–60. http://dx.doi.org/10.1111/j.1747-0285.2011.01130.x.
Astrat'ev, A. A., D. V. Dashko, A. Yu Mershin, A. I. Stepanov e N. A. Urazgil'deev. "ChemInform Abstract: Some Specific Features of Acid Nitration of 2-Substituted 4,6-Dihydroxypyrimidines. Nucleophilic Cleavage of the Nitration Products." ChemInform 32, n. 51 (23 maggio 2010): no. http://dx.doi.org/10.1002/chin.200151070.
Winterbourn, Christine C., e Rex Munday. "Concerted Action Of Reduced Glutathione And Superoxide Dismutase In Preventing Redox Cycling Of Dihydroxypyrimidines, And Their Role In Antioxidant Defence". Free Radical Research Communications 8, n. 4-6 (gennaio 1990): 287–93. http://dx.doi.org/10.3109/10715769009053361.
Jansa, Petr, Antonín Holý, Martin Dračínský, Viktor Kolman, Zlatko Janeba, Petra Kostecká, Eva Kmoníčková e Zdeněk Zídek. "5-Substituted 2-amino-4,6-dihydroxypyrimidines and 2-amino-4,6-dichloropyrimidines: synthesis and inhibitory effects on immune-activated nitric oxide production". Medicinal Chemistry Research 23, n. 10 (9 maggio 2014): 4482–90. http://dx.doi.org/10.1007/s00044-014-1018-9.
Shi, Daqing, Lihui Niu e Qiya Zhuang. "Clean synthesis of pyrido[2,3-d]pyrimidines in aqueous media". Journal of Chemical Research 2005, n. 10 (ottobre 2005): 648–50. http://dx.doi.org/10.3184/030823405774663048.
Kufelnicki, Aleksander, Jan Jaszczak, Urszula Kalinowska-Lis, Cecylia Wardak e Justyn Ochocki. "Complexes of Uracil (2,4-Dihydroxypyrimidine) Derivatives". Journal of Solution Chemistry 35, n. 5 (maggio 2006): 739–51. http://dx.doi.org/10.1007/s10953-006-9017-1.
Novais, H. M., e S. Steenken. "ESR studies of electron and hydrogen adducts of thymine and uracil and their derivatives and of 4,6-dihydroxypyrimidines in aqueous solution. Comparison with data from solid state. The protonation at carbon of the electron adducts". Journal of the American Chemical Society 108, n. 1 (gennaio 1986): 1–6. http://dx.doi.org/10.1021/ja00261a001.
Rostkowska, Hanna, Anna Luchowska, Leszek Lapinski e Maciej J. Nowak. "Photochemical transformations of 4,6-dihydroxypyrimidine and 2-methyl-4,6-dihydroxypyrimidine isolated in low-temperature Ar, Ne and H2 matrices". Chemical Physics Letters 745 (aprile 2020): 137263. http://dx.doi.org/10.1016/j.cplett.2020.137263.
Keerthi Kumar, Chinnagiri T., Jathi Keshavayya, Tantry N. Rajesh, Sanehalli K. Peethambar e Angadi R. Shoukat Ali. "Synthesis, Characterization, and Biological Activity of 5-Phenyl-1,3,4-thiadiazole-2-amine Incorporated Azo Dye Derivatives". Organic Chemistry International 2013 (18 agosto 2013): 1–7. http://dx.doi.org/10.1155/2013/370626.
Vu, Tuan Q., Nikolai V. Yudin, Alexander A. Kushtaev, Thanh X. Nguyen e Sergey A. Maltsev. "Spectroscopic Study of the Basicity of 4,6-Dihydroxypyrimidine Derivatives". ACS Omega 6, n. 22 (24 maggio 2021): 14154–63. http://dx.doi.org/10.1021/acsomega.1c00671.
Kapoor, Bharat, EzzedinA Luhishi, AndrewKK Chung e JakobusC Pauw. "Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency". Indian Journal of Ophthalmology 56, n. 4 (2008): 336. http://dx.doi.org/10.4103/0301-4738.41422.
Malancona, Savina, Mattia Mori, Paola Fezzardi, Marisabella Santoriello, Andreina Basta, Martina Nibbio, Lesia Kovalenko et al. "5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein". ACS Medicinal Chemistry Letters 11, n. 5 (19 marzo 2020): 766–72. http://dx.doi.org/10.1021/acsmedchemlett.9b00608.
Boyd, Vincent A., John Mason, Parimala Hanumesh, Jeanine Price, Charles J. Russell e Thomas R. Webb. "2-Substituted-4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries". Journal of Combinatorial Chemistry 11, n. 6 (9 novembre 2009): 1100–1104. http://dx.doi.org/10.1021/cc900111u.
Shennara, Khaled A., Ray J. Butcher e Frederick T. Greenaway. "Crystal structure of tetraaquabis(pyrimidin-1-ium-4,6-diolato-κO4)manganese(II)". Acta Crystallographica Section E Crystallographic Communications 73, n. 4 (31 marzo 2017): 620–22. http://dx.doi.org/10.1107/s2056989017004649.
Zhang, Xiao-Min, Hui-Liang Zhou e Qi-Lin Hu. "N-(2-Amino-4,6-dihydroxypyrimidin-5-yl)acetamide dihydrate". Acta Crystallographica Section E Structure Reports Online 67, n. 9 (31 agosto 2011): o2526. http://dx.doi.org/10.1107/s1600536811034441.
Metwally, Mohamed Abbas, e Hassan Ali Etman. "The Synthesis of Indeno[l,2:4,5]pyrimido[l,2-a]benzimidazole-13-ones, Indeno[l,2-b]pyrazolo[4,3-e]pyridine-3,5-dione and Related Compounds*". Zeitschrift für Naturforschung B 41, n. 4 (1 aprile 1986): 486–88. http://dx.doi.org/10.1515/znb-1986-0413.
Otutu, O. J., e A. K. Asiagwu. "Synthesis and Application to Polyester and Nylon 6 Fabrics of Hetaryl Bis-Azo Disperse Dyes Based on 6-Amino-2,4-Dihydroxypyrimidine and 4-Methoxy-2-Nitroaniline Moieties". Journal of Scientific Research 11, n. 2 (1 maggio 2019): 215–24. http://dx.doi.org/10.3329/jsr.v11i2.38734.
Tang, Jing, Kasthuraiah Maddali, Yves Pommier, Yuk Y. Sham e Zhengqiang Wang. "Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited". Bioorganic & Medicinal Chemistry Letters 20, n. 11 (giugno 2010): 3275–79. http://dx.doi.org/10.1016/j.bmcl.2010.04.048.
Pace, Paola, M. Emilia Di Francesco, Cristina Gardelli, Steven Harper, Ester Muraglia, Emanuela Nizi, Federica Orvieto et al. "Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors". Journal of Medicinal Chemistry 50, n. 9 (maggio 2007): 2225–39. http://dx.doi.org/10.1021/jm070027u.
Xu, Xue-Jiao, Peng Zheng, Gao-Ping Ren, Mei-Ling Liu, Jun Mu, Jing Guo, Du Cao, Zhao Liu, Hua-Qing Meng e Peng Xie. "2,4-Dihydroxypyrimidine is a potential urinary metabolite biomarker for diagnosing bipolar disorder". Molecular BioSystems 10, n. 4 (2014): 813. http://dx.doi.org/10.1039/c3mb70614a.
de Melo, Eduardo Borges, e Márcia Miguel Castro Ferreira. "Multivariate QSAR study of 4,5-dihydroxypyrimidine carboxamides as HIV-1 integrase inhibitors". European Journal of Medicinal Chemistry 44, n. 9 (settembre 2009): 3577–83. http://dx.doi.org/10.1016/j.ejmech.2009.03.001.
Ofitserova, E. S., A. A. Shklyarenko, I. P. Yakovlev e E. V. Fedorova. "Vilsmeier–Haack formylation of ethyl [(4,6-dihydroxypyrimidin-2-yl)sulfanyl]acetate". Russian Journal of Organic Chemistry 52, n. 9 (settembre 2016): 1374–76. http://dx.doi.org/10.1134/s1070428016090256.
Boyle, Timothy J., Mark A. Rodriguez e Todd M. Alam. "4,6-Dihydroxypyrimidine: a selective bridging ligand for controlled Group IV metal alkoxide structures". Dalton Transactions, n. 24 (2003): 4598. http://dx.doi.org/10.1039/b310087a.
Pacini, Barbara, Salvatore Avolio, Caterina Ercolani, Uwe Koch, Giovanni Migliaccio, Frank Narjes, Laura Pacini, Licia Tomei e Steven Harper. "2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp". Bioorganic & Medicinal Chemistry Letters 19, n. 21 (novembre 2009): 6245–49. http://dx.doi.org/10.1016/j.bmcl.2009.06.106.
MOSKVIN, A. V., N. M. PETROVA, E. A. SEMENOVA, M. SHOPOVA, V. A. GINDIN e B. A. IVIN. "ChemInform Abstract: Azines and Azoles. Part 88. Condensation of 4,6-Dihydroxypyrimidine with Aromatic Aldehydes." ChemInform 25, n. 27 (19 agosto 2010): no. http://dx.doi.org/10.1002/chin.199427164.
Karen, Pavel, Richard L. Harlow, Zhigang Li, Paul Meenan, Patti A. Parziale, Kirsi Ranta e Teófilo Rojo. "The Crystal Structure of 2-Amino-4,6-dihydroxypyrimidine Determined from Powder X-Ray Synchrotron Diffraction." Acta Chemica Scandinavica 52 (1998): 1051–55. http://dx.doi.org/10.3891/acta.chem.scand.52-1051.
He, Tianyu, Tiffany C. Edwards, Jiashu Xie, Hideki Aihara, Robert J. Geraghty e Zhengqiang Wang. "4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease". Journal of Medicinal Chemistry 65, n. 7 (4 aprile 2022): 5830–49. http://dx.doi.org/10.1021/acs.jmedchem.2c00203.
Yazdanbakhsh, M. R., H. Yousefi, M. Mamaghani, E. O. Moradi, M. Rassa, H. Pouramir e M. Bagheri. "Synthesis, spectral characterization and antimicrobial activity of some new azo dyes derived from 4,6-dihydroxypyrimidine". Journal of Molecular Liquids 169 (maggio 2012): 21–26. http://dx.doi.org/10.1016/j.molliq.2012.03.003.
Petrocchi, Alessia, Uwe Koch, Victor G. Matassa, Barbara Pacini, Kara A. Stillmock e Vincenzo Summa. "From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety". Bioorganic & Medicinal Chemistry Letters 17, n. 2 (gennaio 2007): 350–53. http://dx.doi.org/10.1016/j.bmcl.2006.10.054.
Muhammad, Munira Taj, Khalid Mohammed Khan, Arshia, Ajmal Khan, Fiza Arshad, Bibi Fatima, M. Iqbal Choudhary, Naima Syed e Syed Tarique Moin. "Syntheses of 4,6-dihydroxypyrimidine diones, their urease inhibition, in vitro, in silico, and kinetic studies". Bioorganic Chemistry 75 (dicembre 2017): 317–31. http://dx.doi.org/10.1016/j.bioorg.2017.08.018.
Wang, Kuan, Jian-Gang Chen, Bozhou Wang, Yueping Ji, Fengyi Liu, Zhao-Tie Liu, Wenliang Wang, Zhong-Wen Liu, Zhengping Hao e Jian Lu. "Insight into the acidic group-induced nitration mechanism of 2-methyl-4,6-dihydroxypyrimidine (MDP) with nitronium". RSC Advances 6, n. 83 (2016): 80145–57. http://dx.doi.org/10.1039/c6ra18842g.
Krishnakumar, V., e N. Prabavathi. "DFT simulations and vibrational analysis of FTIR and FT-Raman spectra of 2-amino-4,6-dihydroxypyrimidine". Journal of Raman Spectroscopy 39, n. 5 (13 febbraio 2008): 679–84. http://dx.doi.org/10.1002/jrs.1916.
Hoti, Ramiz, Hamit Ismaili, Veprim Thaçi, Gjyle Mulliqi-Osmani, Malësore Pllana-Zeqiri e Agon Bytyqi. "An Efficient Synthesis of Novel 3-[(Heteroaryl-2-ylimino)-methyl]-4-hydroxy-chromen-2-ones and Analogue of Tetrazole Derivatives and Their Antibacterial Activity". Molbank 2021, n. 4 (2 dicembre 2021): M1303. http://dx.doi.org/10.3390/m1303.
Xiao, Bo, e et al. "Crystal structure of aqua-[(2,2’-bipyridine)]-[(2,4-dihydroxypyrimidine- 5-carboxylato)] perchloratocopper(II), Cu(H2O)(C10H8N2)(C5H3N2O4)(ClO4), C15H13ClCuN4O9". Zeitschrift für Kristallographie - New Crystal Structures 227, n. 3 (settembre 2012): 365–66. http://dx.doi.org/10.1524/ncrs.2012.0176.
Stansfield, Ian, Salvatore Avolio, Stefania Colarusso, Nadia Gennari, Frank Narjes, Barbara Pacini, Simona Ponzi e Steven Harper. "Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid". Bioorganic & Medicinal Chemistry Letters 14, n. 20 (ottobre 2004): 5085–88. http://dx.doi.org/10.1016/j.bmcl.2004.07.075.
Summa, Vincenzo, Alessia Petrocchi, Victor G. Matassa, Cristina Gardelli, Ester Muraglia, Michael Rowley, Odalys Gonzalez Paz, Ralph Laufer, Edith Monteagudo e Paola Pace. "4,5-Dihydroxypyrimidine Carboxamides andN-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species". Journal of Medicinal Chemistry 49, n. 23 (novembre 2006): 6646–49. http://dx.doi.org/10.1021/jm060854f.
Li, Xianghong, Shuduan Deng, Xiaoguang Xie e Guanben Du. "Synergistic inhibition effect of 5-aminotetrazole and 4,6-dihydroxypyrimidine on the corrosion of cold rolled steel in H 3 PO 4 solution". Materials Chemistry and Physics 181 (settembre 2016): 33–46. http://dx.doi.org/10.1016/j.matchemphys.2016.06.031.
Summa, Vincenzo, Alessia Petrocchi, Victor G. Matassa, Marina Taliani, Ralph Laufer, Raffaele De Francesco, Sergio Altamura e Paola Pace. "HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis". Journal of Medicinal Chemistry 47, n. 22 (ottobre 2004): 5336–39. http://dx.doi.org/10.1021/jm0494669.
Cushman, Mark, Jeffrey T. Mihalic, Klaus Kis e Adelbert Bacher. "Design and synthesis of 6-(6-D-ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic acid, a potent inhibitor of lumazine synthase". Bioorganic & Medicinal Chemistry Letters 9, n. 1 (gennaio 1999): 39–42. http://dx.doi.org/10.1016/s0960-894x(98)00687-8.
Li, Xin-yang, Jing-wei Liang, Kamara Mohamed O, Ting-jian Zhang, Guo-Qing Lu e Fan-hao Meng. "Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs". European Journal of Medicinal Chemistry 154 (giugno 2018): 267–79. http://dx.doi.org/10.1016/j.ejmech.2018.05.020.
Cushman, Mark, Jeffrey T. Mihalic, Klaus Kis e Adelbert Bacher. "ChemInform Abstract: Design and Synthesis of 6-(6-D-Ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic Acid, a Potent Inhibitor of Lumazine Synthase." ChemInform 30, n. 19 (16 giugno 2010): no. http://dx.doi.org/10.1002/chin.199919169.
Kobayashi, Satoshi, Makoto Ueno, Gakuto Ogawa, Akira Fukutomi, Masafumi Ikeda, Takuji Okusaka, Tosiya Sato et al. "Impact of renal function on the efficacy and safety of S-1 with concurrent radiotherapy for locally advanced pancreatic cancer." Journal of Clinical Oncology 37, n. 4_suppl (1 febbraio 2019): 301. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.301.
Festus, Chioma, Anthony C. Ekennia, Aderoju A. Osowole, Lukman O. Olasunkanmi, Damian C. Onwudiwe e Oguejiofo T. Ujam. "Synthesis, experimental and theoretical characterization, and antimicrobial studies of some Fe(II), Co(II), and Ni(II) complexes of 2-(4,6-dihydroxypyrimidin-2-ylamino)naphthalene-1,4-dione". Research on Chemical Intermediates 44, n. 10 (13 giugno 2018): 5857–77. http://dx.doi.org/10.1007/s11164-018-3460-7.
NOVAIS, H. M., e S. STEENKEN. "ChemInform Abstract: Reactions of Oxidizing Radicals with 4,6-Dihydroxypyrimidines as Model Compounds for Uracil, Thymine, and Cytosine." ChemInform 18, n. 21 (26 maggio 1987). http://dx.doi.org/10.1002/chin.198721086.
NOVAIS, H. M., e S. STEENKEN. "ChemInform Abstract: ESR Studies of Electron and Hydrogen Adducts of Thymine and Uracil and Their Derivatives and of 4,6-Dihydroxypyrimidines in Aqueous Solution." Chemischer Informationsdienst 17, n. 19 (13 maggio 1986). http://dx.doi.org/10.1002/chin.198619054.
-, V. M. Sherekar, N. S. Padole - e K. P. Kakade -. "Synthesis, Characterization and Biological Evaluation of 6-(5-Chloro-8-Hydroxynapthalene-2-yl)-4(4-Hydroxyphenyl)-4-5-Dihydroxypyrimidin-2(1h)-One". International Journal For Multidisciplinary Research 4, n. 6 (28 dicembre 2022). http://dx.doi.org/10.36948/ijfmr.2022.v04i06.1240.
Beylkin, Diane, Gyanendra Kumar, Wei Zhou, Jaehyeon Park, Trushar Jeevan, Chandraiah Lagisetti, Rhodri Harfoot, Richard J. Webby, Stephen W. White e Thomas R. Webb. "Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease". Scientific Reports 7, n. 1 (dicembre 2017). http://dx.doi.org/10.1038/s41598-017-17419-6.