Letteratura scientifica selezionata sul tema "Diagnostic nutritionnel"

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Articoli di riviste sul tema "Diagnostic nutritionnel":

1

Goujon, G. "Cancer de l’anus : diagnostic, bilan initial et stadification". Côlon & Rectum 14, n. 3 (agosto 2020): 133–39. http://dx.doi.org/10.3166/cer-2020-0150.

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Le diagnostic histologique du cancer de l’anus repose sur les biopsies réalisées lors de l’examen proctologique. La recherche d’HPV et de la protéine p16 est recommandée, en lien avec son rôle pronostique. Les progrès techniques et la meilleure accessibilité rendent indispensable dans le bilan initial l’IRM anorectale dans le bilan d’extension locorégional, en complément du scanner TAP. La TEP-18-FDG est presque systématique et l’échoendoscopie anorectale reste intéressante pour les petites tumeurs. Le bilan du terrain ne doit pas être oublié : infection VIH et comorbidités associées, recherche d’autres cancers HPV-induits, évaluation de la continence et de l’état nutritionnel. La recherche d’un déficit en DPD est nécessaire avant un traitement par fluoropyrimidines.
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Harivel, V., D. Grey e R. Gandy. "Nouvelles courbes de croissance & diagnostic de l’état nutritionnel chez l’enfant, quels impacts ?" Nutrition Clinique et Métabolisme 33, n. 1 (marzo 2019): 89–90. http://dx.doi.org/10.1016/j.nupar.2019.01.391.

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Jenner, R., J. F. Munier, E. Munier, E. Merkt, F. Piran, V. Wenger e A. Pradignac. "Impact d’une formation et d’un accompagnement dans le champ nutritionnel sur le diagnostic et la prise en charge nutritionnels de patients hospitalisés dans un CHU". Nutrition Clinique et Métabolisme 35, n. 1 (aprile 2021): 40. http://dx.doi.org/10.1016/j.nupar.2021.01.043.

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Schaeffer, E., J. E. Kurtz, C. François, V. Becker, F. Piran e A. Pradignac. "Évaluation du recueil des paramètres du diagnostic nutritionnel des patients adultes au sein d’un hôpital de jour d’oncohématologie". Nutrition Clinique et Métabolisme 30, n. 2 (giugno 2016): 132. http://dx.doi.org/10.1016/j.nupar.2016.04.062.

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Righini, C. A., N. Timi, P. Junet, A. Bertolo, E. Reyt e I. Atallah. "Évaluation du statut nutritionnel, lors du diagnostic, des patients traités pour un cancer des voies aérodigestives supérieures (VADS)". Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale 130, n. 1 (febbraio 2013): 8–14. http://dx.doi.org/10.1016/j.aforl.2012.11.001.

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Marin, B., J. C. Desport, P. Kajeu, P. Jésus, P. M. Preux e P. Couratier. "Valeur pronostique de l’altération du statut nutritionnel lors du diagnostic des patients atteints de sclérose latérale amyotrophique, centre expert SLA Limoges, France, 1997–2007". Revue d'Épidémiologie et de Santé Publique 58 (settembre 2010): S68. http://dx.doi.org/10.1016/j.respe.2010.06.071.

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Shatenstein, Bryna, Marie-Jeanne Kergoat e Sylvie Nadon. "Anthropometric Indices and Their Correlates in Cognitively-Intact and Elderly Canadians with Dementia". Canadian Journal on Aging / La Revue canadienne du vieillissement 20, n. 4 (2001): 537–56. http://dx.doi.org/10.1017/s0714980800012307.

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RÉSUMÉLes mesures anthropométriques reflètent l'état nutritionnel. Cette recherche a examiné les données provenant de Canadien(ne)s âgé(e)s ayant participé à la première phase de l'Étude sur la santé et le vieillissement au Canada (CSHA-1). Le poids et la taille furent mesurés chez 1 464 personnes vivant dans la communauté et 963 individus en institution. Les sujets institutionnalisés avaient un poids corporel inférieur à ceux vivant en communauté (59,1 ± 13,8 kg. vs. 65,1 ± 14,1 kg.); ils étaient plus petits (160,4 ± 10.1 cm vs. 162,6 ± 10 cm), et leur IMC étaient plus bas (23,3 ± 5,0 vs. 24,6 ± 4,5) (p< .001). Les valeurs anthropométriques furent plus basses chez les femmes, et diminuaient progressivement avec l'âge. Les Québécois avaient une taille plus petite et un poids corporel inférieur à ceux des Canadiens vivant ailleurs. Les mesures anthropométriques ont diminué suivant le diagnostic cognitif, en allant de normal, à «deficit cognitif sans démence» (CIND), à dément; les participants atteints de la démence de type Alzheimer avaient les poids corporels les plus bas. Les facteurs associés au poids corporel étaient différents parmi les participants vivant dans la communauté et en institution.
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Fayemendy, P., N. Calmel, H. Sourisseau, G. Lautrette, P. M. Preux, P. Couratier, J. C. Desport e P. Jésus. "État nutritionnel et métabolique au diagnostic et survie des patients atteints de sclérose latérale amyotrophique (SLA) avec démence frontotemporale versus patients atteints de SLA seule". Nutrition Clinique et Métabolisme 35, n. 1 (aprile 2021): 48. http://dx.doi.org/10.1016/j.nupar.2021.01.059.

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Boutrid, Nada, Hakim Rahmoune, Karim Bouziane-Nedjadi e Abdelkrim Radoui. "Digestive and hepatobiliary manifestations of children with cystic fibrosis in Oran, Algeria". Batna Journal of Medical Sciences (BJMS) 8, n. 1 (4 giugno 2021): 36–41. http://dx.doi.org/10.48087/bjmsoa.2021.8107.

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Introduction. La mucoviscidose reste une affection potentiellement sévère, responsable d’une morbimortalité élevée dans notre pays en raison du retard diagnostique et de prise en charge des enfants vu l’absence de dépistage néonatal. Objectif. Présenter les signes cliniques digestifs et hépatobiliaires des enfants atteints de mucoviscidose au diagnostic et lors de leur suivi. Patients et méthodes. Etude descriptive, transversale et rétrospective conduite au niveau du service de pneumo-allergologie de l’EHS Canastel « Boukhrofa Abdelkader » à Oran, entre 2000 et 2019, concernant les dossiers des enfants avec un diagnostic confirmé de mucoviscidose. Résultats. Sur 51 dossiers d’enfants colligés (49% de garçons, âge moyen = 6.68 +/- 4.24 années), la triade classique avec diarrhée, dénutrition et atteinte pulmonaire était le premier motif d’hospitalisation avec 41% des enfants. Aussi, à l’admission, la diarrhée chronique avec stéatorrhée était présente dans 82,4% des cas, avec 11.8% de déshydratation. Trente-six pour cent (36%) des enfants présentaient également une dénutrition associée. Concernant le système hépatobiliaire, 10% des enfants présentaient une hépatomégalie clinique, avec une lithiase vésiculaire dans un seul cas. Un seul enfant a présenté un prolapsus rectal. Sur le plan thérapeutique nutritionnel, tous les enfants ont reçu des extraits pancréatiques. L’évolution des diarrhées était globalement favorable ; le pourcentage des enfants diarrhéiques étant passé de 82.4% à 37.25% avec une amélioration de l’index de masse corporelle (IMC) chez 42.55% des malades. Conclusion. Les manifestations hépato-digestives sont au premier plan au cours de la mucoviscidose : dans notre cohorte, tous les patients ont présenté au moins un signe d’appel digestif durant leur suivi. Leur reconnaissance et surtout leur prise en charge précoces sont des étapes essentielles en vue d’améliorer le pronostic des enfants atteints de mucoviscidose. Mots clés : Mucoviscidose, Enfant, Algérie, insuffisance pancréatique exocrine, complications digestives, complications hépatobiliaires.
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Senesse, Pierre, e Marie-Paule Vasson. "Nutrition chez le patient adulte atteint de cancer : quand et comment évaluer l’état nutritionnel d’un malade atteint de cancer ? Comment faire le diagnostic de dénutrition et le diagnostic de dénutrition sévère chez un malade atteint de cancer ? Quelles sont les situations les plus à risque de dénutrition ?" Nutrition Clinique et Métabolisme 26, n. 4 (dicembre 2012): 165–88. http://dx.doi.org/10.1016/j.nupar.2012.10.004.

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Tesi sul tema "Diagnostic nutritionnel":

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Gharieb, Katia. "Exposition précoce aux toxiques et déséquilibres nutritionnels : l’inflammation et les lésions précancéreuses de la prostate". Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2017. http://www.theses.fr/2017AZUR4125.

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Les maladies chroniques de l’adulte (maladies cardiovasculaires, cancers, maladies respiratoires et diabète) tuent chaque année dans le monde 38 millions de personnes dont 16 millions avant l’âge de 70 ans. Jusqu’aux années 1990, l’origine de ces pathologies étaient associée au style de vie de l’individu : consommation de tabac, d’alcool, l’inactivité physique et un régime alimentaire déséquilibré. Depuis l’élaboration du concept de DOHaD, identifiant les origines développementales de la santé et des maladies, de nombreuses données montrent que les maladies chroniques de l’adulte ont, en partie, une origine très précoce pendant la période péri conceptionnelle (in utero, premières années de la vie). L’exposition, à cette période, à des déséquilibres alimentaires, des toxiques, des produits chimiques synthétiques perturbant les hormones endogènes (perturbateurs endocriniens, PEs) pourra impacter l’organisme en développement via des modifications épigénétiques qui retiennent la mémoire des facteurs environnementaux auxquels sont soumis les individus. Toutefois, les phénotypes et les mécanismes impliqués sont encore loin d’être décryptés. Au cours de ce travail de thèse, nous nous sommes intéressée aux effets développementaux sur la prostate. En effet, le cancer de la prostate (CaP) est la deuxième cause de cancer et la 5° cause de mort par cancer dans le monde. Les données de la littérature montrent que les déséquilibres alimentaires (régime riche en graisse, HFD) et les PEs œstrogèno-mimétiques sont des facteurs de risque pour ce cancer. Nous avons développé un modèle expérimental de rats (jeunes adultes, 90 jours post-natal) exposés pendant la gestation jusqu’au sevrage à un HFD (60% de graisses), ou à un estrogène (estradiol benzoate, EB) pendant la période néonatale, ou bien à la combinaison des deux, pour explorer les effets sur la prostate (lobe ventral). L’exposition péri natale à l’EB ou à la combinaison EB+HFD diminue le poids de la prostate adulte. Cette anomalie est associée à une inflammation de la prostate modérée (HFD), importante (EB) ou massive (EB+HFD). L’infiltrat est composé essentiellement de macrophages et de lymphocytes T. Cette inflammation est associée à une augmentation dans la prostate du taux de cytokines pro-inflammatoires TNFa, CCL2/MCP1 (EB) mais aussi IL-6 (EB+HFD) ainsi qu’à une dérégulation de l’inflammasome NLRP3. NLRP3 est activé de façon chronique puisque l’on observe une sur expression de ses substrats IL-1b et IL-18. En conclusion, nous montrons que l’exposition péri conception à un estrogène ou à la combinaison RRG+EB programme des lésions prostatiques chez l’animal adulte. Chez l’homme, il est suggéré que des lésions inflammatoires chroniques (atrophie proliférative inflammatoire) seraient, comme pour d’autres organes, une première étape vers le début de la carcinogenèse. Ainsi, notre modèle expérimental permettrait l’étude des étapes précoces de la tumorigenèse prostatique
Non-communicable diseases (NCDs) including cardiovascular diseases, cancers, respiratory diseases and diabetes kill 38 million people worldwide every year, 16 million of them before the age of 70. Until the 1990s, the origin of these pathologies was associated with the lifestyle of the individual: consumption of tobacco, alcohol, physical inactivity and an unbalanced diet. Since the development of the concept of DOHaD, identifying the developmental origins of health and disease, number of evidence showed that NCDs have, in part, an early origin during the peri-conception period (in utero, first years of life). Exposure during this period to food imbalances, toxic chemicals, synthetic chemicals disrupting endogenous hormones (endocrine disruptors, EDCs) may impact the developing body through epigenetic changes imprinted by the environmental factors to which individuals are exposed. However, the phenotypes and mechanisms involved are still far from being decrypted. During this thesis, we focused on developmental effects on the prostate. In fact, prostate cancer (PCa) is the second leading cause of cancer and the fifth leading cause of death by cancer in the world. Data from the literature shows that dietary imbalances (High Fat Diet, HFD) and estrogen-like EDCs are risk factors for this cancer. We developed an experimental model of rats (young adults, 90 days postnatal) exposed during pregnancy until weaning to HFD (60% fat), or estrogen (estradiol benzoate, EB) during the neonatal period, or a combination of both, to explore the effects on the prostate (ventral lobe). Peri-natal exposure to EB or EB + HFD reduces the weight of the adult prostate. This abnormality is associated with low (HFD), moderate (EB) or massive (EB + HFD) prostate inflammation. The infiltrate is composed mainly of macrophages and T lymphocytes. This inflammation is associated with an increase in the prostate of pro-inflammatory cytokine TNFa, CCL2 / MCP1 (EB) but also IL-6 (EB + HFD) as well as a deregulation of the NLRP3 inflammasome. NLRP3 is chronically activated since its substrates IL1b and IL-18 were over expressed. In conclusion, we show that peri-conception exposure to an estrogen or HFD + EB combination programs prostatic lesions in adult animals. In men, it is suggested that chronic inflammatory lesions (proliferative inflammatory atrophy) would, as for other organs, be a first step towards the onset of carcinogenesis. Thus, our experimental model is relevant for the study of the early stages of prostatic tumorigenesis
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Rabetsaroana, Vololona. "Etude de l'état nutritionnel d'enfants admis dans un service de pédiatrie générale à Paris". Paris 5, 1990. http://www.theses.fr/1990PA05P041.

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Issa, Carine. "Régime méditerranéen traditionnel et adiposité dans un échantillon rural au Liban, et qualité nutritionnelle des plats composés". Aix-Marseille 2, 2009. http://www.theses.fr/2009AIX20705.

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L’alimentation Méditerranéenne (Med) traditionnelle est reconnue depuis longtemps pour ses effets bénéfiques dans la prévention des maladies chroniques. Malheureusement, au Liban, comme dans d’autres pays de la Méditerranée, l'alimentation traditionnelle est progressivement remplacée par une alimentation occidentale. Cette évolution défavorable s’accompagne d’une augmentation de la prévalence de l’obésité. Cependant, les régions rurales semblent avoir entamé leur transition nutritionnelle plus tardivement et de façon moins abrupte. Dans ce contexte, deux études complémentaires ont été effectuées afin d'examiner les caractéristiques de l’alimentation de ruraux Libanais, en lien avec l'adiposité. Notre premier objectif a été de tester l’hypothèse selon laquelle l’adhésion à un régime Med traditionnel est associée à une moindre adiposité dans cet échantillon rural. Notre second objectif a été d'estimer la qualité nutritionnelle globale des plats Libanais traditionnels et de la comparer avec celle des plats les plus consommés en France, en se basant sur le nouveau concept de profilage nutritionnel. Les résultats ont montré une association inverse entre la qualité du régime et les marqueurs d’adiposité (ç. à. D. Indice de masse corporelle et tour de taille) lorsque la qualité nutritionnelle a été évaluée avec un nouveau score, le Composite Med, incluant des composantes positives (ç. à. D. Céréales et graines complètes, légumes, fruits), des composantes négatives adaptées à notre échantillon (ç. à. D. Céréales et graines raffinées, boissons sucrées), ainsi que des composantes positives spécifiques au régime Med (ç. à. D. Légumineuses, huile d’olive et poisson). Les résultats de la seconde partie de notre travail ont montré que la moyenne de la quantité de légumes et féculents non-raffinés combinée représentait plus de 50% du poids total dans les plats composés Libanais (LD) et seulement 25% dans les plats composés consommés en France (FD). Les LD étaient significativement plus riches en vitamine C que les FD et contenaient moins d'acides gras saturés et de sodium que les FD. Ainsi, les plats Libanais traditionnels avaient en général une bonne qualité nutritionnelle avec deux fois plus de LD que de FD appartenant à la classe de profil nutritionnel le plus favorable. L'application du concept de profilage nutritionnel à la cuisine traditionnelle Libanaise suggère que ce riche héritage culinaire pourrait être mis à profit pour améliorer la diversité alimentaire et promouvoir une alimentation plus saine au Liban. De plus, nos résultats sont en accord avec l'hypothèse d'un effet protecteur de l'alimentation Med sur l'adiposité (totale et abdominale). Dans l'ensemble, nos travaux suggèrent que la réintroduction des habitudes alimentaires traditionnelles dans les pays Méditerranéens pourrait contribuer à prévenir la progression du surpoids et de l'obésité, et ainsi éviter une dégradation de l'état de santé des populations dans cette région
The traditional Mediterranean (Med) diet has been widely documented for its benefits in the prevention of chronic diseases. Unfortunately, in Lebanon, as in other Med countries, the traditional diet is eroding toward a more westernized diet. This detrimental evolution is accompanied by an increased prevalence of obesity. However, rural areas seem to be experiencing a smoother nutrition transition. In this context, two complimentary studies were performed to document the diet characteristics of a rural sample in Lebanon and the relationship with adiposity. First, we aimed to test the hypothesis that adherence to a traditional Med diet was associated with a lower prevalence of body adiposity in this rural sample. Secondly, we aimed to determine the global nutritional quality of traditional Lebanese dishes as compared to dishes most consumed in France, based on the new concept of nutrient profiling. The findings demonstrated an inverse association between diet quality and adiposity markers (namely, Body Mass Index and Waist Circumference) when dietary quality was assessed with a new Composite Med score, including both positive components of the diet (i. E. Whole grain and cereal products, vegetables, fruit) and negative components adapted to our sample (i. E. Refined grain and cereal products, liquid sweets), along with positive key components of the Med diet (i. E. Legumes, olive oil, and fish). Results of the second part of our work showed that the mean of vegetable and unrefined starches contents combined represented more than 50% of total weight in composite dishes from Lebanon (LD) and only 25% in dishes consumed in France (FD). LD were significantly richer in vitamin C than FD and had significantly lower content in saturated fatty acids and sodium than FD. Thus, traditional Lebanese dishes were found to generally have a good nutritional quality with twice as many LD as FD belonging to the most favorable nutrient profile class. The nutrient profile perspective suggested that the rich traditional cuisine heritage of Lebanon has the potential to improve dietary diversity and healthy eating. Moreover, our results support the concept that adherence to a Mediterranean-type diet is associated with reduced general and abdominal adiposity. Overall, our work suggests that the reintroduction of traditional dietary habits in Mediterranean countries could slow down the increasing trend toward overweight and obesity, and thus prevent detrimental health consequences in populations of this region
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Fassier, Philippine. "Alimentation, consommation d’alcool, activité physique, prise de compléments alimentaires, variation de poids et représentations nutritionnelles : évolution avant/apres diagnostic d’un cancer". Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCD072/document.

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Alors que les survivants du cancer sont à risque plus élevé de second cancer, d’autres pathologies et de déclin fonctionnel ; les facteurs de mode de vie, comme une alimentation équilibrée, une pratique d’activité physique et le contrôle d’un poids sain, peuvent contribuer à prévenir ces risques et améliorer la qualité de vie des survivants du cancer. Dans ce contexte, les objectifs de cette thèse étaient, parmi les survivants du cancer de la cohorte française prospective NutriNet-Santé, 1) d’investiguer les variations du comportement nutritionnel entre avant et après diagnostic de cancer ainsi que la consommation de compléments alimentaires, et 2) d’évaluer les opinions vis-à-vis de certains facteurs nutritionnels, et de les mettre en regard de leurs pratiques alimentaires réelles d’une part, et de leurs sources d’information nutritionnelles d’autre part. Dans un premier temps, nous avons observé des tendances favorables à la santé comme une diminution de la consommation d’alcool et des boissons sucrées non alcoolisées, et d’autres moins favorables comme une diminution de la consommation de légumes et de plusieurs apports en vitamines et minéraux. Un déclin de l’activité physique globale et intense était observé. De manière cohérente, nous avons observé une augmentation des comportements sédentaires, particulièrement chez les femmes, les sujets plus âgés et les patients qui n’étaient pas actif professionnellement. Nous avons observé une perte de poids chez certains cas de cancers colorectaux, alors qu’une prise de poids était observée chez les cas de cancers du sein et de la peau. Les facteurs sociodémographiques et économiques semblaient influencer le risque de prise de poids, suggérant des inégalités sociales de santé (risque plus élevé chez les patients ayant des revenus et un niveau d’étude plus faible). Nos résultats suggéraient que la consommation de compléments alimentaires était largement répandue chez les survivants du cancer, en grande partie sans suivi médical, incluant une proportion non négligeable de patients ayant des pratiques de consommation de compléments alimentaires pouvant être considérées comme « à risque ».Dans un second temps, nous avons observé que les opinions des survivants du cancer concernant certains facteurs nutritionnels semblaient impacter leurs pratiques alimentaires et étaient eux-mêmes impactés par les sources d’informations auxquelles les survivants du cancer avaient eu accès depuis leur diagnostic de cancer. En particulier, les opinions concernant la consommation d’alcool étaient préoccupantes, avec une proportion importante de survivants du cancer qui pensaient que la consommation d’alcool (et plus encore concernant le vin rouge) avait un impact positif sur leur maladie. Les régimes restrictifs pour perdre du poids étaient pratiqués par une grande partie de notre échantillon ; le jeûne était moins pratiqué, mais était loin d’être un phénomène isolé
While cancer survivors are at increased risk for negative conditions as second cancers, other comorbidities, and functional decline ; lifestyle factors, such as a healthy diet, regular exercise and weight control, may contribute to prevent these conditions and improve survivors' quality of life. In this context, aims of this thesis were, among cancer survivors from the French prospective NutriNet-Santé study, to 1) investigate nutritional variations between before and after cancer diagnosis as well as dietary supplements use, and 2) evaluate opinions relating to some diet factors and to weight-loss restrictive diets and fasting practices, and to link them on the one hand to their real practices, and, on the other hand, to their sources of nutritional information.In the first part, our results highlight some healthy behaviors such as a decrease in alcohol and sweetened drinks consumption, but also less favorable trends, such as a decrease in vegetable consumption and in many vitamin and mineral intakes. We also observed a decline in overall and vigorous physical activity after diagnosis, especially in prostate and skin cancers, in men and professionally inactive patients. Concomitantly, we observed an increase in sedentary behaviors, especially in women, older subjects and professionally inactive patients. We also observed that while weight loss was reported in many colorectal cancer patients, a substantial proportion of breast cancer patients gained weight. Sociodemographic and economic factors appeared as important determinants of weight gain, illustrating social inequalities in health (higher risk among patients with lower income and lower education). Our results suggest that dietary supplements use was widespread among cancer survivors, a large amount of which being used without any medical supervision, including a non-negligible proportion of patients having dietary supplement practices which can be considered as “at risk”. In a second part, we observed that opinions from cancer survivors regarding some nutritional factors seemed to impact their dietary practices and were themselves impacted by sources of nutritional information. In particular, opinions regarding alcohol consumption were concerning, with an important proportion of cancer survivors who thought that alcohol consumption (and even more regarding red wine) had a positive impact on their disease. Weight-loss restrictive diets were practiced by a large number of cancer survivors since their diagnosis, while fasting was less practiced, but was far from being an isolated phenomenon
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Phélizon, Claire. "La maladie d'Alzheimer ou les difficultés de l'approche thérapeutique". Bordeaux 2, 1999. http://www.theses.fr/1999BOR2P099.

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Duquesnay, Anne. "Changements de la composition foliaire et de la productivité des hêtraies dans le quart nord-est de la France entre 1970 et 1995". Nancy 1, 1998. http://www.theses.fr/1998NAN10286.

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Des travaux effectués dans des hêtraies situées dans le quart nord-est de la France ont mis en évidence des changements de la composition chimique des sols (un enrichissement en azote et une désaturation des sols) et une eutrophisation de la végétation au cours des 20 dernières années. Afin d'étudier les changements éventuels de la composition foliaire et de la productivité des peuplements pour la même période, 85 placettes de hêtraies situées dans le nord-est de la France, et mises en place dans les années 70, ont été échantillonnées de nouveau en 1995. La comparaison de la composition foliaire de chacune des deux périodes (1969/71 et 1996/97) révèle, indépendamment de la variabilité stationnelle et inter-annuelle des concentrations foliaires, une augmentation significative de la concentration foliaire d'azote et une diminution de la concentration foliaire de phosphore et de magnésium, ainsi qu'une modification de la balance entre éléments. Les changements de productivité ont été appréciés par deux approches complémentaires. Les indices de fertilité, définis comme la hauteur dominante a 100 ans, montrent une dérive positive entre 1970 et 1995, qui pourraient s'expliquer en partie par des biais méthodologiques. Enfin, l'étude dendrochronologie des peuplements met en évidence une augmentation significative de la croissance radiale, particulièrement marquée pour les placettes de l'échantillon situées sur substrat gréseux et pour la période 1850-1995. Pour les placettes situées sur substrat calcaire, la tendance est moins nette et s'exprime seulement à partir de 1940. Les changements climatiques ne semblent pas être en mesure d'expliquer les tendances observées. En revanche, les phénomènes d'eutrophisation et de désaturation des sols observés pour la période 1970-1991 et l'augmentation de la concentration de CO2 atmosphérique pourraient expliquer les augmentations de croissance et les changements de la composition foliaire.
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Schneider, Harald Jörn, Bernhard Saller, Jens Klotsche, Winfried März, Wolfgang Erwa, Hans-Ulrich Wittchen e Günter Karl Stalla. "Opposite associations of age-dependent insulin-like growth factor-I standard deviation scores with nutritional state in normal weight and obese subjects". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-100946.

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Objective: Insulin-like growth factor-I (IGF-I) has been suggested to be a prognostic marker for the development of cancer and, more recently, cardiovascular disease. These diseases are closely linked to obesity, but reports of the association of IGF-I with measures of obesity are divergent. In this study, we assessed the association of age-dependent IGF-I standard deviation scores with body mass index (BMI) and intra-abdominal fat accumulation in a large population. Design: A cross-sectional, epidemiological study. Methods: IGF-I levels were measured with an automated chemiluminescence assay system in 6282 patients from the DETECT study. Weight, height, and waist and hip circumference were measured according to the written instructions. Standard deviation scores (SDS), correcting IGF-I levels for age, were calculated and were used for further analyses. Results: An inverse U-shaped association of IGF-I SDS with BMI, waist circumference, and the ratio of waist circumference to height was found. BMI was positively associated with IGF-I SDS in normal weight subjects, and negatively associated in obese subjects. The highest mean IGF-I SDS were seen at a BMI of 22.5–25 kg/m2 in men (+0.08), and at a BMI of 27.5–30 kg/m2 in women (+0.21). Multiple linear regression models, controlling for different diseases, medications and risk conditions, revealed a significant negative association of BMI with IGF-I SDS. BMI contributed most to the additional explained variance to the other health conditions. Conclusions: IGF-I standard deviation scores are decreased in obesity and underweight subjects. These interactions should be taken into account when analyzing the association of IGF-I with diseases and risk conditions.
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Schneider, Harald Jörn, Bernhard Saller, Jens Klotsche, Winfried März, Wolfgang Erwa, Hans-Ulrich Wittchen e Günter Karl Stalla. "Opposite associations of age-dependent insulin-like growth factor-I standard deviation scores with nutritional state in normal weight and obese subjects". BioScientifica, 2006. https://tud.qucosa.de/id/qucosa%3A26325.

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Objective: Insulin-like growth factor-I (IGF-I) has been suggested to be a prognostic marker for the development of cancer and, more recently, cardiovascular disease. These diseases are closely linked to obesity, but reports of the association of IGF-I with measures of obesity are divergent. In this study, we assessed the association of age-dependent IGF-I standard deviation scores with body mass index (BMI) and intra-abdominal fat accumulation in a large population. Design: A cross-sectional, epidemiological study. Methods: IGF-I levels were measured with an automated chemiluminescence assay system in 6282 patients from the DETECT study. Weight, height, and waist and hip circumference were measured according to the written instructions. Standard deviation scores (SDS), correcting IGF-I levels for age, were calculated and were used for further analyses. Results: An inverse U-shaped association of IGF-I SDS with BMI, waist circumference, and the ratio of waist circumference to height was found. BMI was positively associated with IGF-I SDS in normal weight subjects, and negatively associated in obese subjects. The highest mean IGF-I SDS were seen at a BMI of 22.5–25 kg/m2 in men (+0.08), and at a BMI of 27.5–30 kg/m2 in women (+0.21). Multiple linear regression models, controlling for different diseases, medications and risk conditions, revealed a significant negative association of BMI with IGF-I SDS. BMI contributed most to the additional explained variance to the other health conditions. Conclusions: IGF-I standard deviation scores are decreased in obesity and underweight subjects. These interactions should be taken into account when analyzing the association of IGF-I with diseases and risk conditions.
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Parravano, Jean. "Un système expert de diagnostic médical appliqué à la nutrition". Nancy 1, 1988. http://www.theses.fr/1988NAN10404.

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Intérêt d'une approche heuristique dans l'établissement du diagnostic et proposition de plusieurs niveaux de connaissance pour représenter l'expertise médicale. Application à des enquêtes diététiques et à l'éducation du comportement alimentaire d'adolescents de la région de Nancy
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Axelsson, Karin. "Eating problems and nutritional status after stroke". Doctoral thesis, Umeå universitet, Institutionen för omvårdnad, 1988. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-99332.

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Eating problems and nutritional status were studied in a consecutive series of 104 stroke patients admitted to emergency hospital care. During their stay in hospital eating problems were observed in 46 patients. Certain common types of eating problems were identified: aberrant eating behaviour as regards chewing,lokalization or swallowing, eating small amounts, hoarding of food in the mouth, leakage of food from the mouth and unawareness of eating problems. Poor nutritional status occurred in 16 % of the patients on admission and in 22 % on discharge from the stroke unit. A subgroup of 32 patients hospitalized for 21 days or longer was studied for three weeks. On at least one occasion during these three weeks a poor nutritional status was observed in 18 patients, of whom 17 had eating problems. All subjects who had eating problems during their hospital stay, plus those patients without eating problems but with neurological deficits and those living in a nursing home one year after the stroke (n=36) were selected for a longitudinal study 18 months after the onset of stroke. Eating problems were identified in 23 of these patients during their hospital stay while 21 had such problems when they were followed up. Two patients who could not eat due to severe dysphagia (after a stroke) for three years and 18 months respectively, were successfully trained to eat normally. One patient exhibited impaired oral and hypopharyngeal function and the other impaired hypo- pharyngeal function and a spastic crico-pharyngeal muscle. In both patients training in swallowing was the main remedical measure and one of them also had a myotomy of the spastic muscle.

[2] s., s. 1-45: sammanfattning, s. 49-130: Härtill 6 uppsatser


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Libri sul tema "Diagnostic nutritionnel":

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Smith, G. S. Kiwifruit nutrition: Diagnosis of nutritional disorders. Wellington North, N.Z: Southern Horticulture, 1985.

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D, Lee Robert. Nutritional assessment. 3a ed. Boston: McGraw-Hill, 2003.

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Lee, Robert D. Nutritional assessment. Madison, Wis: Brown & Benchmark, 1993.

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D, Lee Robert. Nutritional assessment. 4a ed. Boston: McGraw-Hill, 2007.

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D, Lee Robert. Nutritional assessment. 2a ed. St. Louis: Mosby, 1996.

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D, Lee Robert. Nutritional assessment. 5a ed. Dubuque, IA: McGraw-Hill, 2010.

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Jones, J. M. Nutritional screening and assessment tools. Hauppauge, N.Y: Nova Science Publishers, Inc., 2005.

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International Symposium on Diagnosis of Nutritional Status od Deciduous Fruit Orchards (1989 Warsaw, Poland). Diagnosis of nutritional status of deciduous fruit orchards: International symposium : Papers. A cura di Sadowski A e International Society for Horticultural Science. Section Fruits. [Warsaw]: ISIS, 1990.

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Escott-Stump, Sylvia. Nutrition and diagnosis-related care. 7a ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012.

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Sylvia, Escott-Stump, a cura di. Nutrition and diagnosis-related care. Philadelphia: Lea & Febiger, 1985.

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Capitoli di libri sul tema "Diagnostic nutritionnel":

1

Wagner, Leigh, Diana Noland e Jeanne A. Drisko. "Nutritional Diagnosis Resources". In Integrative and Functional Medical Nutrition Therapy, 1043–44. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30730-1_56.

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Ronco, Alvaro Luis, e Eduardo De Stéfani. "Prevention After Diagnosis". In Nutritional Epidemiology of Breast Cancer, 203–12. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-2397-9_17.

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Hanhineva, Kati. "Metabolomics in Assessment of Nutritional Status". In Advances in Food Diagnostics, 139–52. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119105916.ch5.

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Howard, Wm James, Giovanni de Simone e Barbara V. Howard. "Definition and Diagnostic Criteria for Metabolic Syndrome". In Nutritional and Metabolic Bases of Cardiovascular Disease, 87–95. Oxford, UK: Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444318456.ch11.

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Okano, C., A. Nishimune, M. Fukuhara, K. Okamoto e M. Hayasaka. "Sugarbeet nutritional diagnosis using remote sensing". In Plant Nutrition for Sustainable Food Production and Environment, 381–82. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-009-0047-9_115.

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Mecklenburg, Lars, e Sarah Beck. "Nutritional, Metabolic, and Toxic Disorders of Nonhuman Primates". In Atlas of Diagnostic Pathology in Nonhuman Primates, 131–37. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-41280-6_4.

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Maeda, Keisuke. "Nutritional Care for Aspiration Pneumonia: Can a Nutritional Approach Change the Clinical Course of Aspiration Pneumonia?" In Respiratory Disease Series: Diagnostic Tools and Disease Managements, 193–203. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4506-1_19.

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Penniston, Kristina L. "Nutritional Prevention of Nephrolithiasis in Children". In Diagnosis and Management of Pediatric Nephrolithiasis, 171–90. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07594-0_11.

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Penniston, Kristina L. "Nutritional Contributors to Nephrolithiasis in Children". In Diagnosis and Management of Pediatric Nephrolithiasis, 77–95. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07594-0_6.

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Ohshimo, Shinichiro. "Fluid and Nutritional Management of ARDS: What Is the Ideal Fluid and Nutritional Management for an ARDS Patient?" In Respiratory Disease Series: Diagnostic Tools and Disease Managements, 105–20. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8371-8_8.

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Atti di convegni sul tema "Diagnostic nutritionnel":

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Ferreira, Eliz Garcia, Jamille Karolyne da Conceição e Ana Paula de Mello. "Nutritional risk patients management in a stroke reference center". In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.328.

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Introduction: Nutritional screening should be used as a tool nutritional risk early identification, aiming at intervention for the prevention of malnutrition and rehabilitation. Objectives: Report nutritional risk management protocol in patients admitted for suspected stroke. Methodology: Experience report on the working method of nutrition team at a stroke reference center. Results: Nutrition screening by a Dietist is applied within 72 hours of admission of all patients admitted to the acute/integral stroke unit. First, NRS-2002 tool is applied, in which the following items are considered: BMI < 20.5Kg/m²; weight loss in the past three months; reduction in food intake in the last week; metabolic stress and age (≥70 years old). Those with a speech-language diagnosis of dysphagia are also considered at nutritional risk. After, anthropometric measurements: weight and height are measured with walking patients, or knee height, brachial and calf circumference of those with cognitive and/or motor disabilities. Individualized nutritional therapy (oral/enteral) is prescribed. In addition, cases are discussed in a multiprofessional daily round to define actions during rehabilitation and in the discharge process (conter- referral to primary care, nutrition advice and continuity of nutritional therapy at home). Conclusions: Establishing a nutritional risk management protocol is important for early identification in post-stroke patients, since nutritional status is directly related to a good prognosis and long-term quality of life.
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"PV-004 - THE COMPLEXITY OF DUAL PATHOLOGY: REGARDING A CASE REPORT OF SEIZURES". In 24 CONGRESO DE LA SOCIEDAD ESPAÑOLA DE PATOLOGÍA DUAL. SEPD, 2022. http://dx.doi.org/10.17579/abstractbooksepd2022.pv004.

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Objectives: Wernicke's encephalopathy (WE) is a potentially reversible neuropsychiatric emergency caused by thiamine deficiency, whose classical triad consists of confusion, ataxia, and oculomotor dysfunction. The diagnosis is missed in 75-80% of cases and approximately 80% of untreated patients develop Korsakoff Syndrome, whereby recognition of nutritional deficiency or any portion of the triad should prompt treatment. We present a case of a 44-year-old Ukrainian man with suspected background of chronic alcohol abuse and psychiatric history of schizoaffective disorder, who presented with acute onset of confusion, psychomotor agitation, gait ataxia and nystagmus. Anamnesis was hampered by the language barrier and absence of past medical history and patient's alcoholic habits remained unclear. After suspicion of WE it was introduced thiamine and diazepam, with significant improvement. After discontinuation of diazepam, the patient presented with several episodes of tonic-clonic seizures. Starting from this case report, we pretend to discuss the differential diagnosis of seizures in dual pathology. Materials and methods: Clinical records and Pubmed search using the keywords: Wernicke’s Encephalopathy, Seizures, Alcohol, Benzodiazepines. Results and conclusions: Seizures are a common presentation of various conditions associated with alcohol use, whose differential diagnosis is difficult, especially in patients with dubious alcohol consumption. Alcohol abuse is a major precipitant of status epilepticus as seizure threshold is raised by alcohol drinking. Seizures may also occur during alcohol withdrawal for which treatment with benzodiazepines is recommended, however carefully, since both abrupt cessation and high-dose use are critical for the appearance of seizures. Although very rare, WE may also present with seizures, whereby overdiagnosis and overtreatment are preferred to prevent persistent neurocognitive impairments. At discharge the diagnostic discussion prevailed and the patient was medicated for seizures with clinical stabilization. The complexity of psychiatric diagnoses in dual pathology requires a longitudinal assessment for a better understanding of clinical conditions as illustrated here.
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Prado, Vanildo, Daniel Buttros, Luciana Buttros de Paula, Benedito de Sousa Almeida Filho, Heloisa Maria de Luca Vespoli, Carla Kamya Pessoa, Eduardo Pessoa e Eliana Aguiar Petri Nahás. "EVALUATION OF METABOLIC SYNDROME AND OBESITY IN BREAST CANCER SURVIVORS SUBJECTED TO INTERDISCIPLINARY APPROACH: A PROSPECTIVE COHORT STUDY". In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2081.

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Objective: The aim of this study was to assess the occurrence of metabolic syndrome (MetS), obesity, and abdominal obesity during the first year after a diagnosis of breast cancer. Methods: This prospective observational study included women with a recent diagnosis of breast cancer. Women aged ≥40 years, with a recent diagnosis of breast cancer, were included. The clinical, anthropometric, and biochemical analyses were performed. Women with three or more diagnostic criteria were considered with MetS as follows: waist circumference (WC) > 88 cm; triglycerides (TG) ≥150 mg/dL; high-density lipoprotein 30 kg/m2 and abdominal obesity with WC >88cm. The measurements were carried out in three moments: first medical assessment (T0m), six months (T6m), and 12 months later (T12m). All patients underwent the interdisciplinary assessment (i.e., nutritional and psychological) at T0m. For statistical analysis, the ANOVA with repeated measures and the chi-square test of trend were used. Results: A total of 72 women with breast cancer were included, with a mean age of 58.4±10.7 years. In the assessment of MetS, BMI, and WC, no difference was observed in the occurrence between the three moments. When comparing the individual metabolic syndrome criteria between the three moments, there was only a statistical difference in the TG and glycemia criteria. The analysis of blood glucose showed a decrease in mean values, with a value of 106.6 mg/dL-T0m, 100.46 mg/dL-T6m, and 98.96 mg/dL-T12m (p=0.004). Regarding TG, an increase in mean values was observed, with a value of 121 mg/dL-T0m, 139.4 mg/dL-T6m, and 148.46 mg/dL-T12m (p=0.003). No cancer treatment showed an impact on the measured criteria. Conclusion: The interdisciplinary approach on the breast cancer survivors demonstrated a positive impact on the control of metabolic syndrome, obesity, and abdominal obesity on the first year of follow-up. Additionally, glycemic indices showed a significant decrease, but an increase in TG values was observed.
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Valenzuela, Víctor. "Nutritional Diagnosis Using AHP with the Garuti Index Compared with DRIS Methodology: A Case Study". In International Symposium on the Analytic Hierarchy Process. Creative Decisions Foundation, 2014. http://dx.doi.org/10.13033/isahp.y2014.128.

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Andrade, Isabela Mascarenhas de, e Adriele Ribeiro França Viriato. "Prognostic factors related to mortality in motor neuron disease at an outpatient care center in Salvador (BA)". In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.330.

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Introduction: Motor neuron disease is neurodegenerative and the understanding of its prognostic factors is crucial promoting better quality of life for patients. Epidemiological, clinical and nutritional factors have been described as influencing disease progression. Objectives: To describe prognostic factors in patients with Motor Neuron Disease at a specialized outpacient care center in Bahia. Methods: This is an observational, and cross-sectional study, carried out by collecting data from medical records of patients with diagnosis of amyotrophic lateral sclerosis (ALS), using forms to acess epidemiology data, clinical characteristics, and nutritional assessment in the beginning of treatment and the time of assessment. The time from the first symptoms until the application of palliative measures was also recorded. Results: 27 patients were enrolled in the study, 51.8% men and 41.8% women, with an average age of 55±11.1 years at diagnosis. No patients were diagnosed with frontotemporal dementia (FTD) and 3.7% had family history of ALS. Weight loss was observed in 95.8% of patients. Among the elderly population, 9% were classified as low weight at the first evaluation, and 81% were classified as such during data collection. Among the adult population, 8.3% were classified as malnourished at their first evaluation, and 27% during data collection. About 81% of the population used some palliative measure. The time between symptoms these measures were of 32 ± 18.6 months for gastrostomy, 38 ± 41.1 months for AMBU use and 49 ± 43.9 months for BiPAP use. Conclusion: A similar distribution of prognostic factors compared with literature was observed, with some particularities such as earlier age of onset, low prevalence of familial ALS and absence of FTD. Significant weight loss was observed, especially in those with bulbar ALS and in the elderly population, which is associated with a poor prognosis. Time from symptoms to palliative measures varied, but was shorter on average in patients with the bulbar form of the disease.
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Moreira, Lorrane de Moura, Bruna Stefany Alves Françozo, Bruno Barcelos Pereira, Camila Almeida Sardinha, Débora Pimenta Alves, Filipe Henrique Almeida Barbosa Godoi, Katherine Oliveira Ferreira e Silvia Oliveira Dourado. "Diagnosis and treatment of Multiple sclerosis: Brazilian and global overview". In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.490.

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Introduction: Multiple sclerosis (MS) is a neurodegenerative autoimmune disease of the central nervous system with a chronic, progressive and inflammatory character. In addition, it presents itself in a heterogeneous way, and can be as an isolated syndrome or as a recurrent remitter, in the first stage, or as progressive, in the second stage. The present work was developed with the objective of determining which is the best form of diagnosis and therapy for multiple sclerosis in Brazil. Methods: The review was performed in PubMed platform, with the descriptors: “multiple sclerosis”, “diagnosis”, “therapy” and “research”. Results: The research result in 148 articles. After a criterious reading and the application of the used criteria, was selected 20 articles. Conclusion: For the diagnosis of this chronic neurological disease, magnetic resonance imaging is used to assess myelination of the different regions of the central nervous system, which is the most suitable for the diagnosis of MS. Μoreover, as a complement, cerebrospinal fluid extraction and blood tests are performed in order to ascertain the concentration of B cells. Regarding therapeutics, this is diversified, including drugs, diets and therapies that stimulate cognition and motor action, such as the use of virtual reality programs and motor images. In relation to drugs, it is of importance that SUS makes natalizumab and ocrelizumab available because they are more efficient and enable users to have a better quality of life. Finally, nutritional monitoring is also suggested to establish a ketogenic or fasting diet in a balanced way
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Awuor, Silas Onyango, e Fidelma C. Too. "Association of Sickle Cell Disease with Nutritional Status Among Under-Five Children and Mediating Role of Hemoglobin Level: Secondary Analysis of Data From 2020-2022 Demographic and Health Survey". In 3rd International Nutrition and Dietetics Scientific Conference. KENYA NUTRITIONISTS AND DIETICIANS INSTITUTE, 2023. http://dx.doi.org/10.57039/jnd-conf-abt-2023-m.i.y.c.n.h.p-31.

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Background: Malnourishment remains the main issue that affect under-five children in Kenya to an overwhelming proportion. The condition is further compounded by the burden of sickle cell disease (SCD). However, association of SCD with stunting, wasting, and underweight in a nationally representative sample of under-five children remains unknown. The main aim of this study was to describe prevalence of under malnutrition by sickle cell status, to evaluate its association with growth faltering ascertained with anthropometric indices, and to explore mediating role of hemoglobin. Methods: The data were availed from the 2020 to 2022 Demographic and Health Survey (DHS) of Kisumu County and the sample comprised 11233 children aged 6–59 months who were successfully genotyped for SCD. The DHS employed a two-stage striated sampling strategy. Sickle SCAN rapid diagnostic test was used for SCD genotyping. Z-scores of length/height-for-age (HAZ), weight-for-height (WHZ), and weight-for-age (WAZ) were computed against the 2006 World Health Organization Child Growth Standards. Logistic regression models were fitted to evaluate association of SCD with stunting, wasting, and underweight. Results: Prevalence of stunting, wasting, and underweight among children with SCD were 55.4% (54.5– 56.4), 9.1% (8.6–9.7), and 38.9% (38.0-39.8), respectively. The odds of stunting were 2.39 times higher (adjusted odds ratio [aOR]) 2.39, 95% CI: 1.26–4.54) among sickle children than those with normal hemoglobin. SCD was also signicantly associated with underweight (aOR 2.64, 95% CI: 1.25–5.98), but not with wasting (aOR 1.60, 95% CI: 0.85–3.02). Hemoglobin level signicantly mediated SCD-HAZ (adjusted indirect effect (aIE) -0.328, 95% CI: -0.387, -0.270), SCD-WHZ (aIE − 0.080, 95% CI: -0.114, -0.050), and WAZ (aIE − 0.245, 95% CI: -0.291, -0.200) associations. The extent of mediation was highest for SCD-HAZ association (adjusted proportion mediated 0.928, 95% CI: 0.535–2.770). Conclusion: We presented convincing evidence of the negative impact of SCD on nutritional status of under-five children. Integration of a nutrition-oriented approach into a definitive SCD care package and its nation-wide implementation could bring promising results by mitigating the nutritional vulnerability of children with SCD Keywords: Sickle cell disease, Nutritional status, Under-five children, Hemoglobin level
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Tsavachidou, Dimitra, Yang Li, Huifang Guo, Wenbin Liu, Eric Jonasch, Pheroze Tamboli e Gordon B. Mills. "Glycogen metabolism provides nutritional support to renal cancer cells under conditions of stress and may serve as a marker of response to antiangiogenic therapy with bevacizumab". In AACR International Conference: Molecular Diagnostics in Cancer Therapeutic Development– Sep 27-30, 2010; Denver, CO. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/diag-10-pr12.

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Innocencio, Giovanna de Camargo, Paulo Roberto Hernandes Júnior, Juliana de Souza Rosa, Patrick de Abreu Cunha Lopes e Jhoney Francieis Feitosa. "Epidemiological profile of Dementia in the state of São Paulo in the last 5 years". In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.175.

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Background: dementia is a syndrome characterized by the presence of a progressive deficit in cognitive function, with interference in social and occupational activities, with risk factors varying with genetic and environmental stressors. The differential diagnosis must identify potentially reversible conditions, of different etiologies, such as metabolic changes, intoxications, and nutritional deficiencies. In primary degenerative dementias and sequelae forms, the etiological diagnosis carries therapeutic and prognostic implications. Objectives: to analyse the current epidemiological profile of dementia in the state of São Paulo in the last 5 years. Methods: a literature review was carried out based on articles available in the Scielo and PubMed database and an observational, descriptive and cross- sectional collection of epidemiological data on dementias available in DATASUS – SUS Hospital Information System (SIH/SUS) – in the last 5 years – January 2016 to December 2020 – assessing the number of hospitalizations, the amount of public spending, mortality rate and permanence. Results: in the analyzed period, 3.105 hospitalizations were observed due to occurrences related to dementia, representing a total expenditure of R$37.847.961,13, with 2017 being the year with the highest number of hospitalizations and responsible for the highest amount spent. The total mortality rate in the 5 years studied was 5,57, corresponding to 173 deaths, with 2020 being the year with the highest rate while 2017 had the lowest rate. The average of the permanence in the hospital was 180 days. Conclusion: patients with dementia need early diagnosis and procedures to reduce the rate of hospitalizations and mortality, as well as public costs. For this, technological innovations, using structural and functional neuroimaging methods, as well as biology and molecular genetics techniques, have presented perspectives for the early diagnosis of dementia.
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Silva Júnior, Mário Luciano de Mélo, Roberta Lorena de Farias Souza, Marcos Vinícius de Souza Vilanova e Marcos Holmes Carvalho. "Subacute combined degeneration of spinal cord vs Miller-Fisher syndrome: a diagnostic challenge". In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.635.

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Context: Ataxic syndromes in the emergency department have a vast differential diagnosis, including immune, nutritional, and other etiologies. Case report: Man, 67yo, alcoholic, but previously healthy, came to ED due to complaints of falls and progressive dysesthesia in lower limbs which started 7 days from admission. He denied other toxic exposures or infectious history, except covid-19 one month before the current symptoms. Physical examination revealed mild hoarseness, left hemipalate paresis, tactile and position sense hypoesthesia, no sensory level, absence of profound reflexes; right hypotonia, global ataxia, and he was unable to walk. Neuroaxis MRI was normal. CSF obtained at D10 had 2 lymphocytes/mm3, 96mg/dL of proteins and no other abnormalities. Hb=13g/ dL, VCM=103fL, B12=424pg/mL, LDH and homocysteine were high. Negative anti-HTLV and -transglutaminase; covid-19 rapid test was positive, but rt-PCR was negative. ENMG revealed moderate sensory-motor axonal polyneuropathy. We hypothesized that the main differential diagnoses were subacute combined degeneration of spinal cord (although high level of protein in CSF) and Miller-Fisher syndrome (although ophthalmoparesis was absent). Considering that there was no motor nor respiratory symptoms, we did not offer pulse therapy and opted for B12 vitamin replacement. The patient had a favorable response to therapies and was able to walk at two weeks of treatment. Conclusions: We did not define the etiology of this case, however, it is important to keep B12 deficiency in mind (even when it is into the lab reference range) and to pay attention to post-viral atypical manifestations, mostly in the context of the current covid-19 pandemic.

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