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Articoli di riviste sul tema "CVS/pharmacy (Firm)"

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Wilpiszewska, Katarzyna, Adrian Krzysztof Antosik, Beata Schmidt, Jolanta Janik e Joanna Rokicka. "Hydrophilic Films Based on Carboxymethylated Derivatives of Starch and Cellulose". Polymers 12, n. 11 (22 ottobre 2020): 2447. http://dx.doi.org/10.3390/polym12112447.

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The carboxymethylated derivatives of starch (CMS) and cellulose (CMC) were used for film preparation. The infrared spectroscopy revealed that crosslinking via ester bridges with citric acid occurred between the two polysaccharide derivatives. The effect of polysaccharide derivatives ratio on physicochemical properties of prepared films was evaluated. Generally, the values of tested parameters (moisture absorption, surface roughness, and mechanical and thermal properties) were between the values noted for neat CMS or CMC-based films. However, the physicochemical properties of the system with equal CMS/CMC weight ratio diverged from this trend, i.e., the highest tensile strength, the highest Young’s modulus (ca. 3.4 MPa and ca. 4.9 MPa, respectively), with simultaneously the lowest moisture absorption (18.5% after 72 h) have been noted. Such systems could potentially find application in agriculture or pharmacy.
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Gusminarti, Gusminarti, Khairani Khairani e Fajri Kurniawan. "Pemenuhan Kewajiban Perpajakan Apoteker Pemilik Usaha Apotik Pasca Diundangkanya UU Cipta Kerja". Jurnal Ilmu Hukum, Humaniora dan Politik 4, n. 3 (24 aprile 2024): 408–17. http://dx.doi.org/10.38035/jihhp.v4i3.1964.

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In 2021 the government issued Minister of Health Regulation Number 14 of 2021 concerning Standards for Business Activities and Products in the Implementation of Risk-Based Business Licensing in the Health Sector (hereinafter abbreviated as Minister of Health Regulation No. 14 of 2021). In this regulation there are several changes, one of which is that the pharmacy must be owned by a pharmacist. If the pharmacy is not owned by a pharmacist, the capital owner may collaborate with the pharmacist by agreement before a notary. With this provision, there have been several changes for a pharmacist, one of which is regarding the fulfillment of tax obligations. Tax obligations for pharmacists who work only as pharmaceutical technical personnel, their tax obligations that must be fulfilled are only based on the KUP Law and Article 21 of the Income Tax Law Number 36 in 2008, which was most recently refined by Law Number 7 of 2021 concerning Harmonization of Tax Regulations. namely tax deductions by third parties, in this case by pharmacies. Meanwhile, with the Pharmacist's status as a Pharmacy owner, the fulfillment of his tax obligations will increase in accordance with Tax regulations, namely Business Entities. The problem is what if, during the course of the pharmacy business, the pharmacist who owns the pharmacy which was established based on the agreement resigns, what happens to fulfilling his tax obligations. In this regard, there are three problems that the researcher raises, first, what is the description of pharmacy ownership by pharmacists in West Sumatra, second, how to fulfill tax obligations for pharmacists as pharmaceutical workers and pharmacy owners in West Sumatra. third, problems encountered in fulfilling tax obligations by pharmacists who own pharmacies. In West Sumatra, the research uses research methods with an empirical juridical approach, descriptive research type, the data required is primary and secondary data as well as data collection techniques, interviews and document studies, data processing is carried out using qualitative analysis methods. The results of research on pharmacy ownership in West Sumatra are currently in various forms of business, namely Limited Liability Companies and Individual Businesses such as CVs and Firms so that ownership of Pharmacies is still owned by investors and currently there are 5 Pharmacies which are processing the extension of their Pharmacy Business Licenses and some have transferred their ownership to Children of financiers because they have completed their pharmacy studies, and there are also those who are currently processing business permits in the form of individual PT. Meanwhile, the tax obligations carried out by pharmacists as pharmacy business owners have not yet been implemented because currently pharmacies that use pharmacists as pharmacy owners with non-legal entity business forms are still in the process of processing their permits and legal entities. Problems encountered in fulfilling the tax obligations of pharmacists as business owners Pharmacies are still not visible, because the current status of Pharmacists still has the status of a Pharmaceutical Personnel, so their tax obligations are only limited to Income Tax Article 21.
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EMAN, A. M. Al-Jawadi, e I. Majeed MOHAMMED. "ELECTROCHEMICAL SENSORS BASED ON POLY (L-PHENYL ALANINE) FILM ON MWCNT FOR DETERMINATION OF TPS". Periódico Tchê Química 17, n. 35 (20 luglio 2020): 579–90. http://dx.doi.org/10.52571/ptq.v17.n35.2020.49_eman_pgs_579_590.pdf.

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In this study, cyclic voltammetry (CV) is presented with a sensitive electrochemical technique for the assessment of the anti-cancer medicine Toposar (TPS). The electrode was formed on the surface of a modified glassy carbon electrode with MWCNT using a coating of L-phenyl alanine to become the new electrode in a formula (PPA-MWCNT/GCE). PPA was polymerized at pH 8.0, which showed advanced advantages for the study and estimation of TPS electroanalysis treatment. A group of factors on the bare glassy carbon electrode were studied to enhance the electrode 's work to study TPS, including these factors(Influence of pH, calibration curve, the stability of the electrode, scan rate, deposition potential, voltage step, equilibration time, deposition time). As a result of the electrode development, the stability of the prepared electrode was observed with the PPA layer with the Morphology of the layer by the SEM analysis showing the morphology of PPA/GCE and MWCNTs/PPA/GCE by SEM, respectively. The PPA film width on TPS response has higher sensitivity on the surface of MWCNTs/PPA/GCE compared to GCE and increased redox reversibility with 8 cycles number. The CV of 5.0 nM TPS on GCE with scanning rates of between 50 and 400 mV.s?1 This reaction was predicted for an irrevocable electrode mechanism. A comparison was made between the TPS CVs on the MWCNPs, and the PPA modified electrode with the bare GCE at pH 7.0 with a scan rate of 100 mV.s?1, the oxidation current is 11.18 times higher than the comparable one on the bare GCE.
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Rich, Darryl S. "Using outside Compounding Firms during Drug Shortages; CMS Interpretation of Medication Security; Refrigerator Temperature Checks; More on Pharmacist Review of Orders; Nurse Dispensing; Storing IV Admixtures in Other Departments". Hospital Pharmacy 37, n. 5 (maggio 2002): 537–68. http://dx.doi.org/10.1177/001857870203700513.

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This column addresses questions from readers about any issue, process, standard, or future direction of the Joint Commission, whether it relates to home care, the hospital, or other practice environment. The objective is to give you a better insight into the Joint Commission accreditation process in your own practice site. Any question is fair game.
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Penfornis, S., L. Just, M. Monville, A. Cantero e F. Berthet. "Éducation thérapeutique : mise en place et évaluation d’un atelier du médicament dans un pôle clinique d’hospitalisation de psychiatrie adulte". European Psychiatry 30, S2 (novembre 2015): S155. http://dx.doi.org/10.1016/j.eurpsy.2015.09.313.

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Dans le cadre des programmes d’éducation thérapeutique du patient et suite à la demande d’un pôle clinique, la pharmacie des hôpitaux de Saint-Maurice a mis en place début 2015 un atelier du médicament dans 2 unités de l’établissement à l’attention des patients sortants. Ce poster présente le contenu de l’atelier ainsi qu’une évaluation des séances à 5 mois. L’atelier est proposé individuellement par le psychiatre de l’unité au patient sortant. La séance est ensuite animée par un pharmacien ainsi qu’un infirmier de l’unité à raison d’une heure tous les 15 jours. Il consiste en une séance interactive collective de 5 patients environ (individuelle à défaut de patients). Au moyen d’outils variés (tableau, film, boîtes vides, plans de soins, quizz, post-it, plaquettes informatives), les thématiques suivantes sont abordées : brainstorming autour du mot « médicament », notions de médicaments « pivots », « d’appoint » ou « correcteurs », reconnaissance des effets indésirables éventuels, rappels d’interactions médicamenteuses majeures, hygiène de vie, etc. À l’issue de la séance, un questionnaire anonyme est complété par le patient pour évaluer la séance. À 5 mois, 100 % des patients (n = 17) sont satisfaits par le contenu et la présentation des thèmes abordés ; la durée de la séance leur paraît correcte à 88 % ; 47 % des patients avaient des attentes avant l’atelier et celui-ci a permis d’y répondre pour 94 % d’entre eux. Quatre-vingt-quatorze pour cent des patients considèrent les informations reçues comme utiles dans la connaissance de leur maladie. Enfin, 35 % souhaiteraient pouvoir assister à une séance supplémentaire après leur sortie. Cinq mois après la mise en place de l’atelier dans ces 2 unités, le bilan s’avère positif tant par la satisfaction des patients que celle des soignants (meilleure alliance thérapeutique). Un projet de déploiement de cet atelier aux patients dans les structures extrahospitalières est en cours.
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Singh, Vinita, e Donald Harvey. "3447 Effects of intranasal ketamine on uncontrolled cancer related pain". Journal of Clinical and Translational Science 3, s1 (marzo 2019): 40–42. http://dx.doi.org/10.1017/cts.2019.99.

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OBJECTIVES/SPECIFIC AIMS: If intranasal ketamine can be utilized for pain control in cancer patients, this could provide them with superior analgesia and better quality of life, without the risk of significant respiratory depression associated with opioid medications. We seek to obtain preliminary data via a clinical trial addressing safety, feasibility, and utility of this novel technique for the treatment of persistent uncontrolled cancer pain. These findings would be an important initial step towards testing the effectiveness of intranasal ketamine as a non-opioid medication for cancer pain used as potential maintenance outpatient therapy. These initial findings would be applied to a subsequent trial to determine the effectiveness and associated toxicities of ketamine in a larger sample of cancer patients, and address the compelling need to identify new, successful management therapies for cancer pain. Specific Aims: 1. To evaluate (pharmacodynamic) effects of NAS ketamine on Patient Reported Outcomes (PROs), such as pain scores, side effects, depression, quality of life, and functional status. A clinical trial will be conducted where NAS ketamine will be given to a sample of patients with cancer related pain. Patient Reported Outcomes (PROs), such as pain scores, depression, quality of life, and functional status will be noted on Numerical Pain Rating Scale (NPRS), Montgomery Asberg Depression Rating Scale (MADRS), and Edmonton Symptom Assessment (ESAS), Eastern Cooperative Oncology Group (ECOG) and Patient Reported Outcome Measurement Information System (PROMIS) scales respectively. 1. To measure pharmacokinetics of NAS ketamine through analysis of ketamine and its metabolite norketamine to determine pharmacokinetic properties. During this clinical trial blood samples will be drawn at specified intervals and sent for analysis. 3. To determine opioid sparing effect of NAS ketamine. Opioid use will be measured by documenting use of rescue medications prior to and during the study and by evaluating total opioid consumption prior to and during the study. METHODS/STUDY POPULATION: Study sample: In the search for improved therapies for chronic cancer pain, medications with novel mechanisms of action have been sought. One such promising pharmacologic approach is ketamine. We specifically intend to measure utility of ketamine in patients with pain related to cancer or cancer treatment. Ketamine has shown to reverse central sensitization and opioid tolerance in rat models. Since ketamine is Scheduled III in United States and has abuse potential, we do not intend for ketamine to replace opioids, but use in patients who have failed opioid therapy. Since the investigators of the study practice at Emory, subjects will be from oncology and pain clinics (the supportive oncology clinic, oncology clinics, the pain clinic and Acute Pain Service) at Emory. The trial will be conducted at the Phase 1 Unit of the Winship Cancer Institute (WCI) at Emory. Subjects may be identified and contacted via telephone with information about the study prior to their next clinic appointment in order to allow time for them to consider the study. Eligibility criteria: Patients will be eligible to participate if they are: 1. Adults with uncontrolled cancer related pain a. Male and female subjects at least 18 years of age. b. Patients with uncontrolled pain related to cancer or cancer treatment. c. Uncontrolled pain will be defined as i. pain which persists for more than 7 days and is rated >/=4 on NPRS, and/or ii. use of breakthrough medication more than 4 times in 24 hours d. Failed other pain medications such non-steroidal anti-inflammatories such as ibuprofen, acetaminophen, opioids such as tramadol, hydrocodone, oxycodone etc. and antineuropathics such as gabapentin. 2. Able to provide informed consent a. Patients who are able to understand written and verbal English. Patients will be excluded from the study if they have any of the following: 1. Conditions increasing the risk of side effects from ketamine a. Conditions not safe due to cardiovascular effects of ketamine i. Presence of severe cardiac disease-EF <15% in patients with known history of cardiac disease ii. Uncontrolled Stage 2 hypertension or greater (systolic blood pressure > 160 and/or diastolic blood pressure >100) iii. Baseline tachycardia, HR >100 b. Conditions not safe due to potential effect of ketamine on intracranial and intraocular pressure i. Presence of elevated ICP ii. Uncontrolled glaucoma c. Presence of uncontrolled depression or other psychiatric comorbidity with psychosis 2. Conditions not safe due to potential side effects reported in ketamine abusers a. History of liver disease b. History of interstitial cystitis 3. Conditions where delivery of intranasal medications may be unreliable a. Active allergic or infectious rhinitis b. Patients with lesions of nasal mucosa 4. Conditions where fetus may be exposed to ketamine in utero (ketamine is category C medication) a. Pregnant women, nursing mothers and women of childbearing potential not using contraception known to be highly effective. b. Highly effective contraception methods include combination of any two of the following: Use of oral, injected or implanted hormonal methods of contraception or; Placement of an intrauterine device (IUD) or intrauterine system (IUS); Barrier methods of contraception: condom or occlusive cap (diaphragm or cervical/vault caps) with spermicidal foam/gel/film/cream/ vaginal suppository; Total abstinence; Male/female sterilization. 5. Conditions with medication abuse potential a. Illicit substance abuse within the past 6 months b. Documented history of medication abuse/misuse (e.g. Unsanctioned dose escalation, broken opioid agreement etc.) 6. Conditions where ketamine metabolism may be altered, resulting in erroneous dose response relationship a. Clinical requirement for medications that are concurrent inducers or strong inhibitors of CYP3A4. CYP3A4 substrates are allowed. (Ketamine is metabolized by CYP3A4) Study sample limitations: Subject factors that may affect the final resultant study sample of subjects with full data for analysis. 1. Subjects who may not get pain relief with ketamine may not follow up and resulting incomplete data not eligible for analysis that may erroneously enhance positive effect of ketamine on pain relief. To account for this effort will be made to document the reason for lack of follow-up by contacting patient via telephone or at next scheduled clinic visit within Emory Healthcare. 2. Since patients coming to Emory are typically insured, the study will not adequately capture indigent population. It is not the intention of the current study to investigate differences in pain characteristics or responses of patients with insurance vs indigent population and will need to be addressed via future trials. Since this is a single center trial, the results of this trial might lack external validity required to support widespread changes in practice. This will be a pilot trial to figure out likely most efficacious dose. If this trial is successful, a multi-site randomized clinical trial will be conducted next. Primary Study Measures Primary exposure Intranasal Ketamine for cancer related pain Ketamine is an FDA approved anesthetic with amnesic, analgesic, dissociative, and sedative properties. It is unique among anesthetic agents in that it does not depress cardiovascular and respiratory systems. Ketamine is a noncompetitive, antagonist of N-methyl-D-aspartate (NMDA) receptors that blocks the NMDA channel in the open state by binding to the phencyclidine (PCP) site located within the lumen of the channel. Antagonism of NMDA receptors produces antinociception of persistent or neuropathic pain in animal models and analgesia in pain states in humans. The NMDA receptor is believed to play a role in the development of opioid tolerance and ketamine has been shown in a rat model to prevent fentanyl-induced hyperalgesia and subsequent acute morphine tolerance 5. Ketamine also interacts at a number of other receptor sites to block pain. Some of these sites include voltage-sensitive calcium channels, depression of sodium channels, modulation of cholinergic neurotransmission, and inhibition of uptake of serotonin and norepinephrine. Ketamine also interacts with kappa and mu opioid receptors; however, in humans, naloxone, an opioid antagonist, does not antagonize the analgesic effects of ketamine. Safety and efficacy of ketamine as an anesthetic and analgesic agent is well-documented 2-4. Ketamine is not labeled by the FDA as an analgesic agent. Low (subanesthestic) doses of ketamine have minimal adverse impact upon cardiovascular or respiratory function but produce analgesia and modulate central sensitization, hyperalgesia, and opioid tolerance. Cancer pain, especially in end stages, can be very complicated and is mediated by a variety of pathways: visceral, nociceptive, neuropathic and central. If ketamine can be utilized for pain in end stage cancer patients, this could provide them with superior analgesia and better quality of life, without the risk of significant respiratory depression associated with opioid medications. One of the challenges that we face with ketamine is the route of administration. The most common route is intravascular or intramuscular. Although it has been given orally and rectally, the bioavailability of ketamine when given via these routes is limited to 20-30%. Intranasal (NAS) administration has advantages of being needle free method of administration with potential for outpatient therapy. It lacks hepatic first pass effect resulting in higher bioavailability compared to oral route. Large surface area, uniform temperature, high permeability and extensive vascularity of the nasal mucosa facilitate rapid systemic absorption of intranasal administered drugs 6. In the pilot trial conducted by the study investigators, single dosage of intranasal ketamine has been shown to be feasibility and effective option for temporary pain reduction in patients with cancer related pain. The investigators now seek to obtain feasibility and efficacy data on long-term use of intranasal ketamine for cancer related pain. Ketamine is a scheduled III medication. A physician with a DEA license can order intranasal ketamine from a compounding pharmacy. Primary outcome of interest: Pain scores will be recorded on Numerical Pain Rating Scale (NPRS) at regular intervals throughout the study. NPRS is the most responsive tool to document pain intensity when compared to Visual Analogue Scale (VAS) and Visual Rating Scale (VRS) for measuring pain, 7 showing higher compliance rates, better responsiveness, ease of use, and good applicability relative to VAS/VRS8. Minimal clinically important differences (MCIDs) for pain ratings varies substantially based on patient population and statistical technique used, range of 0.4 to 3.7 points has been reported as a MCID. In general, improvements of pain severity</=1.5 points on NPRS could be seen as clinically irrelevant 9-13. Above that value, the cutoff point for “clinical relevance” depends on patients’ baseline pain severity, and ranges from 2.4 to 5.3 11-13. Higher baseline scores require larger raw changes to represent clinically important differences 14. Primary aim: To determine efficacy of intranasal ketamine in reducing cancer related pain. A clinical trial will be conducted to determine effect of intranasal ketamine on cancer related pain. Pain scores will be recorded on Numerical Pain Rating Scale (NPRS) at regular intervals throughout the study. Minimal clinically important differences (MCIDs) for pain ratings varies substantially based on patient population and statistical technique used, range of 0.4 to 3.7 points has been reported as a MCID. In general, improvements of pain severity</=1.5 points on NPRS could be seen as clinically irrelevant 9-13. Above that value, the cutoff point for “clinical relevance” depends on patients’ baseline pain severity, and ranges from 2.4 to 5.3 11-13. Higher baseline scores require larger raw changes to represent clinically important differences 14. Several clinical trials for pain have reported a reduction of 2 points on NPRS to be clinically important.15-17 Therefore for the purposes of this study, MCID of 2 was used for sample size calculations. A prior research study done by Carr et al. studied effects of intranasal ketamine for breakthrough pain in patients with chronic pain of various etiologies. 18 Total number of subjects in this study was 20 (4 of these had cancer related pain).This study demonstrated a mean reduction of 2.7 units on NPRS (P<0.0001), with standard deviation of 1.87. Since MCID is 2, effect size using this (MCID/SD) = 1.05. Power and sample size table: Assumptions: 1. T-test is the appropriate test (may not be the appropriate test since we have a small sample size and may not be able to assume normality of means based on the central limit theorem) 2. Distribution of reductions in pain score is normal 3. Effect size of 1.05 is clinically meaningful; Sample Size: A sample size of 7 from a population of 20 (in the study done by Carr etal.) achieves 80% power to detect a NPRS difference of −2 between the null hypothesis mean of 0.0 and the alternative hypothesis mean of 2 with an estimated standard deviation (SD) of 1.87 and with a significance level (alpha) of 0.05 using paired t-test assuming that the actual distribution is normal. We will include 10 patients to account for the possibility that the observed pain reduction in the current study may be different than the study done by Carr, as in this study patients were given ketamine for breakthrough pain, as opposed to for baseline pain. We will enroll 25 patients in the study to account for potential dropouts. RESULTS/ANTICIPATED RESULTS: Majority of subjects experienced the largest decrease in their pain with the 10mg IV dose. Side effects included nausea/vomiting and a feeling of unreality. All side effects resolved by the end of each study visit. No severe adverse events occurred. DISCUSSION/SIGNIFICANCE OF IMPACT: Further study is required to elucidate safety of NAS ketamine with long term use for cancer related pain.
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Nishijima, K. A., M. M. Wall, L. C. Chang, Y. Wei e D. K. W. Wong. "First Report of Association of Mucor circinelloides on Noni (Morinda citrifolia) in Hawaii". Plant Disease 95, n. 3 (marzo 2011): 360. http://dx.doi.org/10.1094/pdis-11-10-0815.

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Noni (Morinda citrifolia) is a popular medicinal plant found in tropical or subtropical regions of the world. The fruit and juice extracts have properties that are reportedly therapeutic for diabetes, high blood pressure, and certain types of cancer (1,4). In our studies on noni juice produced from fruit collected from the Kohala and Puna districts of the island of Hawaii from 2008 to 2010, Mucor circinelloides f. sp. circinelloides was isolated from 85% of 157 juice samples and observed with up to 75% incidence on fruit surfaces during fermentation processing in glass jars. Fungal growth, appearing 14 to 21 days in storage at 22°C, was pale yellow to tan brown and was associated with wounded surfaces. Single-spore strains, KN 06-2 (2006; ripe fruit puree) and KN 08-08 (2008; fermented juice; CBS 124110), identified by Centraalbureau voor Schimmelcultures by molecular methods were 97.3% similar in internal transcribed spacer sequence to the type strain (CBS 195.68). M. circinelloides f. sp. circinelloides strains (KN 08-08, KN 09-06, or KN 10-02) (2008 to 2010; fermented juice) were inoculated by pipetting an aliquot of 100 μl of fungus strain spore suspension (1 × 105 to 1.33 × 106 spores/ml) onto firm, yellow maturity noni fruit that were washed, surface disinfected, and either wounded (surface cuts) or nonwounded. Controls consisted of no inoculation and sterile distilled water (SDW) inoculation treatments. Ten to twenty each of wounded and nonwounded fruit comprised each inoculation treatment. Fruit were incubated in acrylic bins with a layer of distilled water at the bottom, and sealed with snap-on lids. The bins were incubated on a lab bench at 22 to 23°C under fluorescent lights. Fruits were evaluated for presence of fungal growth and severity of symptoms. To determine viability of spores on inoculated fruit without symptoms, surfaces were swabbed with sterile cotton swabs dipped in SDW, streaked on potato dextrose agar (PDA) plates, and incubated at 22°C under fluorescent lights. The inoculation experiment was conducted twice. Nonwounded fruit inoculated with M. circinelloides f. sp. circinelloides strains did not result in infections (KN 09-06 and KN 10-02) or produced slight mycelial growth (0 to 20%; KN 08-08). Wounded fruit inoculated with any of the three strains resulted in 85 to 100% infection of moderate severity. There were no infections in noninoculated or SDW treatments of nonwounded or wounded fruit. Koch's postulates were fulfilled with the reisolation of M. circinelloides f. sp. circinelloides from selected fruit exhibiting soft tissue, discoloration, and sporulating yellowish green mycelial growth. Swab washes from asymptomatic surfaces of inoculated nonwounded fruit resulted in the growth of M. circinelloides f. sp. circinelloides on PDA, proving viability of the spores and confirmed that the fungus is primarily pathogenic only on wounded fruit surfaces. To our knowledge, this is the first report of M. circinelloides as a wound pathogen of noni fruit. The quality of fermented noni juice may be affected by the presence of M. circinelloides f. sp. circinelloides but can be remedied by pasteurization that does not affect antitumor properties (unpublished data). This fungus is also a reported pathogen of mango (2) and peach (3). References: (1) J. Li et al. Oncol. Rep. 20:1505, 2008. (2) K. Pernezny and G. W. Simone. Phytopathol. News 34:25, 2000. (3) C. Restuccia et al. J. Food Prot. 69:2465, 2006. (4) M. Y. Wang et al. Acta Pharmacol. Sin. 23:1127, 2002.
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Smith, J. Mark. "Trimming the Retail: The investment outlook for CVS’s growth strategy". International Journal of Business & Economic Development 11, n. 02 (11 novembre 2023). http://dx.doi.org/10.24052/ijbed/v011n02/art-01.

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CVS Health Corporation owns the retail pharmacy chain and also owns CVS Caremark, the pharmacy benefits manager, and the Aetna health insurance provider (Kolakowski, 2023). Recent acquisitions in 2022 and 2023 include Oak Street Health, Inc., and Signify Health. CVS’s proactive growth strategy aims to acquire health care firms across various sectors of health care, yet the management is not averse to divesting the firm of less profitable subsidiaries. In November 2021 the firm announced the closing of 300 stores per year through 2024. A decline in stock price of CVS would suggest analyzing whether the company is still a good long-term investment. A deeper study may be warranted, but seven methods should suffice to either reject CVS immediately or accept CVS for further consideration. The analysis includes the following: The price-to-earnings ratio or P/E multiple approach for validating stock price. Evaluating expected return of the stock with the capital asset pricing model (CAPM). The corporate valuation model using free cash flows for stock-price valuation. A review of the company’s dividend history. Comparison of the company’s capital structure with its peers. Evaluating the company’s historical stock prices. Review of the recent financial statements and the five categories of financial ratios to determine the overall health of the firm. As a company with a large retail business unit, CVS stock would be considered a moderately conservative investment. A decision on long-term investing in CVS stock would consider the risk and potential returns. Subject to further scrutiny, this study accepts CVS as a potential investment choice. Although the acceptance is based on analysis, the author makes no guarantee of future results. This paper is the original work of the author and is not previously published.
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Andersen, Martin, e Sebastian Bauhoff. "The Share Price Effect of CVS Health’s Announcement to Stop Selling Tobacco: A Comparative Case Study Using Synthetic Controls". Forum for Health Economics and Policy 20, n. 1 (21 giugno 2016). http://dx.doi.org/10.1515/fhep-2015-0045.

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Abstract We study how the announcement by CVS Health, a large US-based pharmacy chain, to stop selling tobacco products affected its share price and that of its close competitors, as well as major tobacco companies. Combining event study and synthetic control methodologies we compare measures of CVS’s stock market valuation with those of a peer group consisting of large publicly listed firms that are part of Standard & Poor’s S&P 500 stock market index. CVS’s announcement is associated with a short-term decrease in its share price, whereas close competitors have benefitted from CVS’ decision. We also find a negative share price effect for Altria, the largest US domestic tobacco firm. Overall our findings are consistent with markets expecting consumers to shift from CVS to alternative outlets in the short-run, and interpreting CVS’ decision to drop tobacco products as signal that other firms may follow suit.
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"Company News". Asia-Pacific Biotech News 05, n. 12 (11 giugno 2001): 229–38. http://dx.doi.org/10.1142/s0219030301001033.

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GlaxoSmithKline and Shanghai Medical Institute Set up Combinatorial Chemistry Lab. GeneMedix to Take On Schering for Cancer Drug in China. Roche and China's Genome Center to Identify Disease-related Genes. Pharmagenesis and Tianjin Zhong Xin Enter Joint Venture. Korean Biotech Startups Show Impressive Developments. aaiPharma to Establish Joint Venture in China. US Firm Given Approval to Conduct Clinical Trials of Cancel Drug in China. Taiwan's Uni-President Group Sets up US Subsidiary. Uni-President Halts Investment in Vita Genomics. HK's JDH Helps CNS of US to Expand Its International Distribution Network. GeneProt Opens World's Largest Proteomic Discovery Center in Geneva. Takeda Discovers Metastasis Suppressor Peptide Ligand. Fujisawa to Transfer Animal Health Business to Schering-Plough. Phase 2 Trial of Chugai's Gastroparesis Drug On Hold. PPL New Zealand Expansion to Go Ahead. Pfizer is Open to Alliances with Local Indian Companies. Wockhardt-Bayer Tie-Up to Market Antibiotic in India. Sanofi Acquires Torrent Pharma's Stake in India. Thai Food Company Aims to Capture Shanghai Market.
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Libri sul tema "CVS/pharmacy (Firm)"

1

Josh, Flum, CVS/pharmacy (Firm), Harvard Business School e Harvard Business School Publishing Corporation, a cura di. CVS, Jon Roberts and Josh Flum [videorecording]. Boston, MA: Harvard Business School Publishing, 2007.

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