Letteratura scientifica selezionata sul tema "Cumulative diagnosis"
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Articoli di riviste sul tema "Cumulative diagnosis":
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Wang, Shun, Yongbo Li, Khandaker Noman, Dong Wang, Ke Feng, Zheng Liu e Zichen Deng. "Cumulative spectrum distribution entropy for rotating machinery fault diagnosis". Mechanical Systems and Signal Processing 206 (gennaio 2024): 110905. http://dx.doi.org/10.1016/j.ymssp.2023.110905.
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Ponsioen, Cyriel Y. "Diagnosis, Differential Diagnosis, and Epidemiology of Primary Sclerosing Cholangitis". Digestive Diseases 33, Suppl. 2 (2015): 134–39. http://dx.doi.org/10.1159/000440823.
Abstract (sommario):
According to recent guidelines, primary sclerosing cholangitis (PSC) is diagnosed when a patient has a cholestatic liver enzyme profile, characteristic bile duct changes on imaging, and when secondary causes of sclerosing cholangitis are excluded. In patients with a clinical suspicion but normal cholangiography, a liver biopsy is indicated to establish a diagnosis of small duct PSC. Several other disease entities such as IgG4-associated cholangitis (IAC), cholangiocarcinoma (CCA), and secondary causes of sclerosing cholangitis such as choledocholithiasis, AIDS-cholangiopathy, ischemia, surgical bile duct trauma, or mast cell cholangiopathy can mimic PSC. IAC can be differentiated from PSC by applying the HISORt criteria including the serum IgG4 level. In cases where serum IgG4 is less than 2 × ULN, the ratio of IgG4/IgG1 >0.24 is indicative for IAC. Choledocholithiasis with recurrent cholangitis as a cause of sclerosing cholangitis can pose a conundrum, since PSC itself is associated with an increased prevalence of gallstones. The epidemiology of PSC worldwide has been poorly described. Incidence and prevalence rates vary from 0-1.3 and 0-16.2 per 100,000 inhabitants respectively. However, these figures are not based on population-based cohorts. A recent large population-based cohort from the Netherlands reported an incidence of 0.5 and a prevalence of 6/100,000. Approximately 10% fulfil the criteria for small duct PSC. At diagnosis of PSC, concurrent inflammatory bowel disease (IBD), primarily ulcerative colitis or Crohn's colitis is present in 50%, but increasing to 80%, 10 years or more after diagnosis. Conversely, 3% of IBD patients will develop PSC. PSC predisposes to malignancy. The estimated cumulative risk of developing CCA after 30 years is 20%. For colorectal carcinoma in PSC/colitis patients, the estimated cumulative risk at 30 years is 13%.
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Rosenberg, Rebecca E., Walter E. Kaufmann, J. Kiely Law e Paul A. Law. "Parent Report of Community Psychiatric Comorbid Diagnoses in Autism Spectrum Disorders". Autism Research and Treatment 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/405849.
Abstract (sommario):
We used a national online registry to examine variation in cumulative prevalence of community diagnosis of psychiatric comorbidity in 4343 children with autism spectrum disorders (ASD). Adjusted multivariate logistic regression models compared influence of individual, family, and geographic factors on cumulative prevalence of parent-reported anxiety disorder, depression, bipolar disorder, and attention deficit/hyperactivity disorder or attention deficit disorder. Adjusted odds of community-assigned lifetime psychiatric comorbidity were significantly higher with each additional year of life, with increasing autism severity, and with Asperger syndrome and pervasive developmental disorder—not otherwise specified compared with autistic disorder. Overall, in this largest study of parent-reported community diagnoses of psychiatric comorbidity, gender, autistic regression, autism severity, and type of ASD all emerged as significant factors correlating with cumulative prevalence. These findings could suggest both underlying trends in actual comorbidity as well as variation in community interpretation and application of comorbid diagnoses in ASD.
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SHIVASHANKAR, RAINA, EDWARD V. LOFTUS, WILLIAM J. TREMAINE, TIM BONGARTZ, W. SCOTT HARMSEN, ALAN R. ZINSMEISTER e ERIC L. MATTESON. "Incidence of Spondyloarthropathy in Patients with Crohn’s Disease: A Population-based Study". Journal of Rheumatology 39, n. 11 (15 settembre 2012): 2148–52. http://dx.doi.org/10.3899/jrheum.120321.
Abstract (sommario):
Objective.Spondyloarthritis (SpA) is an extraintestinal manifestation of inflammatory bowel disease with significant clinical effects, although the frequency is uncertain. We assessed the cumulative incidence and clinical spectrum of SpA in patients with Crohn’s disease (CD) in a population-based cohort.Methods.The medical records of a population-based cohort of Olmsted County, Minnesota, residents diagnosed with CD between 1970 and 2004 were reviewed. Patients were followed longitudinally until migration, death, or December 31, 2010. We used the European Spondylarthropathy Study Group, Assessment of Spondyloarthritis international Society (ASAS) criteria and modified New York criteria to identify patients with SpA. The Kaplan-Meier method was used to estimate the cumulative incidence of SpA following diagnosis of CD.Results.The cohort included 311 patients with CD (49.8% females; median age 29.9 yrs, range 8–89). Thirty-two patients developed SpA based on ASAS criteria. The cumulative incidence of SpA after CD diagnosis was 6.7% (95% CI 2.5%–6.7%) at 10 years, 13.9% (95% CI 8.7%–18.8%) at 20 years, and 18.6% (95% CI 11.0%–25.5%) at 30 years. The 10-year cumulative incidence of ankylosing spondylitis was 0, while both the 20-year and 30-year cumulative incidences were 0.5% (95% CI 0–1.6%).Conclusion.We have for the first time defined the actual cumulative incidence of SpA in CD using complete medical record information in a population-based cohort. The cumulative incidence of all forms of SpA increased to approximately 19% by 30 years from diagnosis of CD. Our results emphasize the importance of maintaining a high level of suspicion for SpA when following patients with CD.
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Cohen, Lisa R., Denise A. Hien e Sarai Batchelder. "The Impact of Cumulative Maternal Trauma and Diagnosis on Parenting Behavior". Child Maltreatment 13, n. 1 (febbraio 2008): 27–38. http://dx.doi.org/10.1177/1077559507310045.
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Dannefer, Dale. "Racism and Cumulative Dis/Advantage in Healthcare Access: Implications for the Life Course". Innovation in Aging 4, Supplement_1 (1 dicembre 2020): 586. http://dx.doi.org/10.1093/geroni/igaa057.1958.
Abstract (sommario):
Abstract Despite its origins in the study of race in America in Gunnar Myrdal’s American Dilemma, research on cumulative dis/advantage (CDA) and the life course has paid little attention to the significance of racism in the overall production and patterning of CDA. Building on recent work that has reviewed the life-course implications of the inscribing of racist interests in social policy, this paper explores the life-course implications of race bias in another domain, specifically the domain of medical diagnosis, where algorithm formulas have been shown to disadvantage black patients based on economic and other parameters. Even with training, experimental evidence comparing human and AI diagnostics have demonstrated that despite improvements, residual racism is evident in differential diagnoses. We consider the life-course implications of this and similar race-based differentials in organizational decision-making as a component in systems of cumulating dis/advantage.
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Stuver, Robert, Nivetha Ganesan, Ahmet Dogan, Zachary D. Epstein-Peterson, Paola Ghione, William Johnson, Natasha Lewis et al. "Cumulative Incidence of Myeloid Neoplasms in Patients with Nodal T-Follicular Helper Cell Lymphoma". Blood 142, Supplement 1 (28 novembre 2023): 4438. http://dx.doi.org/10.1182/blood-2023-182272.
Abstract (sommario):
Introduction: Certain T-cell lymphomas (TCL), in particular nodal T-follicular helper (TFH) cell lymphomas, including angioimmunoblastic TCL (AITL), commonly develop on a background of mutations identified in clonal hematopoiesis (CH). Divergent clonal evolution can result in both nodal TFH cell lymphomas and myeloid neoplasms (MN). As peripheral TCLs are commonly treated with combination and dose intensive chemotherapy, there is a risk that these therapies could promote an evolution to MN. The frequency at which this occurs is unclear. Methods: We conducted a retrospective search for any patient with an International Classification of Disease (ICD) code referring to a TCL. Then, we identified patients with a concomitant ICD code referring to either myelodysplastic syndromes (MDS), acutemyeloid leukemia (AML), or a myeloproliferative neoplasm (MPN). Once the initial query was performed, we individually reviewed each patient and included only patients meeting the following criteria: (1) A histologically-confirmed diagnosis of either peripheral TCL, not otherwise specified (PTCL-NOS) or nodal TFH cell lymphoma by an MSK hematopathologist between 1/1/02 and 7/1/23; (2) Presentation to MSK at lymphoma diagnosis; (3) At least 6 months of follow-up (unless death from lymphoma); (4) if relevant, a histologically-confirmed diagnosis of a MN by an MSK hematopathologist. Histological diagnoses were recorded as documented in the pathology electronic record in accordance with the WHO criteria in place at the time of diagnosis. In particular, at our center, prior to 2016, cases of PTCL-NOS were not routinely assessed for TFH phenotype, as nodal TFH cell lymphoma was only added to the WHO classification in 2016. Cases documented herein as PTCL-NOS were not re-reviewed to determine TFH phenotype. Only patients who received systemic treatment were included (systemic steroids were not considered systemic treatment). CI of MN was evaluated using the reverse Kaplan-Meier method treating death as a competing risk. Results: We identified a total of 376 patients with either PTCL-NOS (N=178) or nodal TFH cell lymphoma (N=198; AITL N=184; nodal TFH cell lymphoma, NOS N=13; nodal TFH cell lymphoma, follicular-type=1). In total, 24 patients with a MN and either PTCL-NOS or nodal TFH cell lymphoma were identified. Nine had a MN that preceded the TCL diagnosis (AML: 2; MDS: 1; myelofibrosis: 2; CMML: 2; MDS/MPN: 1; polycythemia vera: 1)-these patients were excluded for CI calculation. Fifteen patients were diagnosed with a MN subsequent to lymphoma diagnosis and treatment (AML: 5; MDS: 8; CMML: 1; chronic neutrophilic leukemia: 1). Of the 198 patients with nodal TFH cell lymphoma, nine developed a MN. The CI of developing a MN among all patients at 2, 5, 10, and 15 years was 1.1%, 4.4%, 4.8%, and 5.8%. The CI of developing a MN among those with known nodal TFH cell lymphoma at the same timepoints were 1.6%, 4.5%, 5.3% and 7.1%. The median follow up among survivors was 4.1 years (range: 0.5-18). The median age at MN diagnosis was 72.6 years (range: 45-81), and the median time from lymphoma diagnosis to MN diagnosis was 2.6 years (range: 0.3-10.4). Four patients had either prior RT or chemotherapy for non-lymphoma conditions. Prior to MN diagnosis, ten patients (67%) received etoposide and seven patients (47%) received autologous stem cell transplant (ASCT) (six with BEAM, one with cyclophosphamide plus total body irradiation). The median number of therapies (including ASCT) prior to MN diagnosis was 2 (range: 1-5). At the time of MN diagnosis, 10 patients had relapsed TCL and were receiving lymphoma therapy. No patients had undergone alloSCT prior to the diagnosis of a MN. Next generation mutational profiling with MSK-IMPACT-Heme had previously been performed for eight of the 15 patients (on lymphoma tissue). All except one had mutations in TET2 and/or DNMT3A. Conclusions: Herein we report the CI of MN in a cohort of patients with TCL, with particular attention to nodal TFH cell lymphomas given known CH mutations and the genotoxic stress of combination chemotherapy. As more patients have prolonged survival after initial therapy for TCL, further analysis, including baseline genetics and prospective characterization for clonal expansion and acquired mutations during therapy, could identify those at highest risk for developing a MN. Further characterization of our cohort and comparison to patients who did not develop a MN is ongoing.
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Tzur Bitan, Dana, Daniella Berzin, Khalaf Kridin, Yaron Sela e Arnon Cohen. "Alopecia Areata as a Proximal Risk Factor for the Development of Comorbid Depression: A Population-based Study". Acta Dermato-Venereologica 102 (14 marzo 2022): adv00669. http://dx.doi.org/10.2340/actadv.v102.1622.
Abstract (sommario):
Alopecia areata and depression tend to co-occur; however, their temporal association has not been comprehensively investigated. The aim of this study was to examine the temporal association between alopecia areata and depression. The study included only cases with a comorbid presentation of alopecia areata and depression (n = 1,936), extracted from the databases of the Clalit Health Services, Israel. Survival analyses were used to assess the cumulative probability of receiving alopecia areata as comorbid diagnosis in the years following depression, and vice versa, compared with the opposite trajectory. The results indicate that patients with alopecia areata had greater odds of subsequent depression within 2 years from alopecia areata diagnosis, and showed a steeper increase in cumulative probability of depression as time progressed (log-rank =336.38, p < 0.001), compared with the opposite trajectory. All patients with alopecia areata had comorbid depression within 10 years of alopecia areata, compared with 70% of depression patients receiving diagnoses of comorbid alopecia areata within the same time-frame.
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Anto, Marissa, Shannon C. Shipley, Shavonne Massey e Christina L. Szperka. "Adverse Childhood Experiences Are Associated With Seizures in Children". Neurology: Clinical Practice 13, n. 2 (10 marzo 2023): e200136. http://dx.doi.org/10.1212/cpj.0000000000200136.
Abstract (sommario):
Background and ObjectiveTo assess the relationship between adverse childhood experiences (ACE/ACEs) and epilepsy.MethodsWe performed a cross-sectional retrospective cohort analysis using population-based data from the 2018 and 2019 National Survey of Children's Health to examine caregiver-reported ACE exposures and their relationship to caregiver-reported physician diagnoses of epilepsy or seizure disorder in children. ACEs elicited in the survey included questions about experience of violence, household dysfunction, and food and housing insecurity. Adjusting for age, race, and income level, we used logistic regression to test the relationships between cumulative ACE score and current seizure disorder or epilepsy diagnosis and to examine which specific ACEs were individually associated with current seizure disorder or epilepsy diagnosis.ResultsThe study population consisted of 59,963 participants; 52.2% were female, and 47.8% were male. Participant ages ranged from 0 to 17 years. A current diagnosis of epilepsy or seizure disorder was reported in 377 (0.63%) participants, and 22,749 (37.9%) participants had one or more ACE exposures. As the number of ACEs increased, odds of current epilepsy or seizure disorder diagnosis increased by 1.14 (95% confidence interval 1.07–1.22). Five ACE exposures demonstrated a high association with a current diagnosis of epilepsy or seizure disorder: food/housing insecurity, witnessing domestic violence, household mental illness, neighborhood violence, and parent/guardian incarceration.DiscussionMultiple ACE exposures were individually associated with reporting a diagnosis of epilepsy or seizure disorder. An increase in cumulative ACE exposures increased odds of having current diagnosis of epilepsy or seizure disorder.
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Stevenson, Carl W., e Meghan M. Leis. "The Cumulative Complexity Model and Repeat Falls". Professional Case Management 23, n. 4 (2018): 190–203. http://dx.doi.org/10.1097/ncm.0000000000000279.
Tesi sul tema "Cumulative diagnosis":
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Mendes, Luciane Frizo. "A contribuição da fisioterapia em grupo na recuperação e reabilitação de pacientes com LER/DORT". Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-25032009-092642/.
Abstract (sommario):
Introdução: As atividades com grupos complementando os procedimentos terapêuticos são freqüentemente utilizadas na área de saúde do trabalhador, especialmente para os pacientes com LER/DORT. Este estudo tem por objetivo avaliar os possíveis benefícios da associação do tratamento cinesioterapêutico convencional com dinâmicas de grupo e verificar se o tratamento fisioterapêutico em grupo potencializa os efeitos da cinesioterapia em pacientes com LER/DORT. Método: Participaram do estudo 24 pacientes com diagnóstico de LER/DORT que foram distribuídos aleatoriamente para os dois tipos de intervenção: individual e em grupo. O protocolo de cinesioterapia foi o mesmo para as duas intervenções e teve duração de dez sessões. Os pacientes submetidos à intervenção em grupo participaram de dinâmicas grupais com temáticas previamente estabelecidas para instigar a discussão de aspectos considerados importantes durante o tratamento. A análise das intervenções foi feita por meio da avaliação do quadro doloroso (EVA, Questionário de Dor de McGill e Questionário Nórdico de Sintomas Osteomusculares), da avaliação da funcionalidade (Questionário DASH) e da avaliação da amplitude de movimento das articulações dos membros superiores. Além disso, foi realizada uma entrevista semi-estruturada para avaliar qualitativamente o impacto dessas intervenções no quadro clínico e na qualidade de vida destes pacientes. Resultados: Na avaliação quantitativa do quadro doloroso foi observado que a intervenção em grupo não produziu efeitos para o controle da dor, especialmente para diminuição da intensidade álgica. A análise do questionário DASH revelou que o tratamento individual e o em grupo não produziram efeitos na funcionalidade das atividades de vida diária e do trabalho. O aumento da amplitude de movimento em todas as articulações de membros superiores em ambas as intervenções não foi considerado significativo. Entretanto, a análise qualitativa apontou que os pacientes que participaram da intervenção em grupo relataram uma percepção de melhora do quadro doloroso e da funcionalidade em suas vidas; houve uma reflexão gerada a partir das dinâmicas de grupo trazendo uma nova percepção de saúde e do adoecimento Conclusão: A intervenção em grupo não potencializou os efeitos da cinesioterapia no controle do quadro doloroso, na melhora da funcionalidade e no aumento das amplitudes de movimento das articulações de membros superiores, mas o tratamento cinesioterapêutico convencional associado a dinâmicas de grupo permitiu uma abordagem mais global do processo de adoecimento, recuperação e reabilitação do paciente com LER/DORT e modificou as estratégias de enfrentamento dos processos dolorosos e dos conflitos cotidianos desses indivíduosIntroduction: The group activities are often used to complement therapeutic procedures in the laborers health area, especially for RSI/WMSD patients. This studys aim is to evaluate the possible benefits of associating the conventional kinesiotherapeutic treatment with group dynamics and check if the group physical therapeutic treatment potentializes the effects of kinesiotherapy in RSI/WMSD patients. Method: Twenty four RSI/WMSD patients took part in the study. They were randomly distributed for both kinds of interventions: the individual and the group treatments. The kinesiotherapy protocol was the same for both interventions and it lasted ten sessions. The patients submitted to group intervention took part in group dynamics with previously established themes to instigate the debate on aspects considered important during treatment. The interventions analysis was performed by the evaluation of pain conditions (VAS, McGill Pain Questionnaire, NMQ), of functionality (DASH Questionnaire), and of the upper limb joint movements. Furthermore, a semi-structured interview was performed to qualitatively evaluate the impact of these interventions in these patients clinical condition and quality of life. Results: In the quantitative evaluation of the pain condition it was evidenced that the group intervention was not effective for pain control, especially in the decrease in the intensity of pain. The DASH questionnaires analysis revealed that the individual and the group treatments were not effective in the functionality of daily life and labor activities. The increase in the movement amplitude in every upper limb joint in both interventions was not considered significant. Nonetheless, the qualitative analysis pointed out that those patients who took part in the group intervention reported the perception of improvement in the pain condition and in functionality in their lives; a reflection born within the group dynamics brought a new perception on health and illness. Conclusion: The group intervention did not potentialize the effects of kinesiotherapy in controlling pain, in improving functionality, and in increasing movement amplitudes in the upper limb joints, but the conventional kinesiotherapeutic treatment associated to group dynamics allowed a more global approach of the RSI/WMSD patients illness, recovering, and rehabilitation process and modified the strategies for dealing with these individuals pain processes and daily conflicts
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Zhao, Yanqing. "Contributions à la détection précoce de chatter et à l’identification des bifurcations de période-N basée sur une approche de diagnostic cumulatif". Electronic Thesis or Diss., Université de Lorraine, 2020. http://www.theses.fr/2020LORR0250.
Abstract (sommario):
Le diagnostic cumulatif des systèmes dynamiques nécessite la détection, l’identification et la caractérisation des dégradations naissantes. Son application à l'usinage à grande vitesse, par exemple, pourrait s’appuyer sur l’analyse des phénomènes de bifurcations de période-N pour détecter et identifier les chatters (broutages) naissants et améliorer la qualité des produits et des processus de fraisage. Jusqu'à présent, de nombrecuses méthodes efficaces ont été proposées pour détecter les broutages naissants et identifier les bifurcations de période-N. Cependant, ces méthodes peinent à mettre en œuvre ces tâches de manière fiable et précise. Le but de la présente thèse est de développer et mettre en œuvre des méthodes de détection de broutages naissants et d’identification de bifurcations de période-N dans une approche de diagnostic cumulatif temps réel. Afin de détecter les défauts de broutages naissants (early-chatter), nous avons proposé trois méthodes de détection et une méthode d’identification pour le diagnostic cumulatif. La première méthode peut être utilisée pour détecter à distance les broutages naissants. La deuxième méthode détecte rapidement les broutages naissants dans des conditions spécifiques de fonctionnement et de mesure. Mais dans la pratique, les conditions de fonctionnement et de mesure sont complexes et variables. Pour s'adapter aux différentes conditions de fonctionnement et de mesure, nous avons proposé une troisième méthode et cette dernière détecte de manière fiable les broutages naissants. On note également que dans les processus de fraisage, les broutages peuvent naître avec une bifurcation de type période-N ou de type Hopf. La qualité d'usinage sous un processus de bifurcation de type période-N est moins critique que celle de type Hopf. Ainsi, il est indispensable d’identifier précocement les bifurcations de type période-N pour améliorer l'efficacité d'usinage. Pour cela, nous avons développé une méthode d’identification du type et de la taille des bifurcations de période-N. Nous avons également prouvé l'efficacité des méthodes proposées, en utilisant deux modèles de processus de fraisage de référence. De plus, les méthodes proposées peuvent être utilisées pour le diagnostic de défaut d'autres systèmes dynamiques, tels que les systèmes de conversion d'énergie par modulation de largeur d'impulsion ou systèmes de paliers ou d’engrenageCumulative diagnosis of dynamic systems requires the detection, identification, and characterization of incipient degradations. Its application to high-speed machining, for instance, could rely on period-N bifurcations phenomena analysis to detect and identify early-chatters and improve the quality of milling products and processes. Up to now, many efficient methods were proposed to detect early-chatter and identify period-N bifurcations. But these methods are struggling to implement these tasks reliably and accurately due to the complex nonlinear characteristics of their dynamic behaviors, the noise, and the variation of their operating conditions. The present thesis aims to develop and implement methods of early-chatter detection and period-N bifurcations identification within a real-time cumulative diagnosis approach. Aimed at early-chatter detection, we proposed three detection methods and one identification method for the cumulative diagnosis. The first method can be used to detect early-chatters remotely. The second one detects early-chatter quickly under specific operating and measuring conditions. However, in practice, the operating and measuring conditions are complex and variable. To adapt to different operating and measuring conditions, we proposed a third method, and the latter detects early-chatter reliably. It is also noted that in milling processes, the early-chatter can give rise to a bifurcation of period-N or Hopf type. The machining quality under the bifurcation process of the period-N type is less critical than that under the Hopf bifurcation type. To improve machining productivity and ensure the required machining quality, we can mill the workpiece under the condition of period-N bifurcations. Thus, it is compulsory to identify the early period-N bifurcations for improving machining productivity. For that purpose, we developed a method for identifying the type and size of the period-N bifurcations. We also proved the effectiveness of the proposed methods, using two benchmark milling process models. Besides, the proposed methods can be used for fault diagnosis of other dynamic systems, such as the pulse energy conversion systems or bearing or gearing systems
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Khoshab, Nima. "Necrotizing fasciitis: a cumulative review and new techniques in emergency room diagnosis". Thesis, 2016. https://hdl.handle.net/2144/16995.
Abstract (sommario):
Necrotizing fasciitis (NF) is a rare and life threating soft-tissue infection specific to the skin’s fascia layer. It is most often encountered in the peripheries, abdominal wall, and perineum and has numerous etiologies and associated pathogens. Early diagnosis and rapid surgical debridement are essential in treating NF as the infection progresses rapidly and mortality rate increases significantly with time. The current difficulty in initial diagnosis is due to the lack of obvious skin findings early on in the infection. Laboratory tests, including the laboratory risk indicator for necrotizing fasciitis (LRINEC) score, gas on imaging tests, and physical exam findings are the current clues to an early diagnosis but official diagnosis can only be confirmed by surgical exploration and discovery of a lack of resistance to dissection in the fascia layer. The LRINEC score analyzes one variable, specifically C-reactive protein (CRP), which is often not included in routine laboratory tests skin infections at the emergency department (ED). Furthermore, no specific set of physical exam findings has been distinctly associated with diagnosis of NF over other soft-tissue infections and the most specific imaging tests are too expensive for routine use. A new and modified LRINEC score based only on routine ED laboratory tests as well as an additional objective scoring system for physical exam findings are the next steps toward rapid diagnosis. This approach requires large-scale retrospective statistical analyses of NF cases across the country for identification of the most prevalent physical exam findings and abnormal laboratory values.
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Daly, Corinne. "Patterns of Diagnostic Imaging and Cumulative Effective Radiation Dose among Long-term Survivors of Malignancies". Thesis, 2012. http://hdl.handle.net/1807/33642.
Abstract (sommario):
Introduction: This study described patterns of imaging and cumulative effective dose (CED) from diagnostic radiation in young adult survivors (YAS) of malignancies and cancer-free controls in Ontario.
Methods: Persons aged 20-44 diagnosed with malignancy between 1992 and 1999 who lived at least 5 years without recurrent disease were matched to controls without a prior cancer diagnosis. The rate at which YAS received diagnostic studies and associated CED was compared to controls using multivariable regression techniques.
Results: 20,911 YAS and 104,524 controls were included. YAS received CT scanning at a significantly higher rate than controls (rate ratio = 3.49, 95% confidence interval [CI]: 3.37 – 3.62. YAS received a 4.57-fold higher CED than controls (95% CI: 4.20 – 4.57).
Conclusions: YAS are exposed to diagnostic radiation at significantly higher rates than controls even after 5 years of recurrence-free survival. Alternative imaging techniques not associated with radiation should be considered for these patients.
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Vieira, Mariana Reis. "Spatial distribution of the severity of lung cancer at diagnosis – is it related to socioeconomic factors and access to primary health care?" Master's thesis, 2021. http://hdl.handle.net/10451/48684.
Abstract (sommario):
Trabalho de projeto de mestrado em Bioestatística, Universidade de Lisboa, Faculdade de Ciências, 2021O cancro do pulmão é dos cancros mais fatais a nível mundial. As estimativas em 2018 para Portugal indicam que 4671 indivíduos morreram de cancro do pulmão, o que corresponde a 16.1% do total de mortes causadas por cancro. Estima-se que existam 5284 novos casos por ano, correspondendo a 9.1% de todos os cancros. A taxa de incidência para homens é 38.8 por cada 100000 habitantes enquanto que para mulheres é 12.6 por cada 100000 habitantes, o que corresponde a um aumento de 75%. A elevada taxa de mortalidade neste tipo de cancro pode ser justificada pelo facto de se tratar de uma doença assintomática. Cancros em estadios avançados têm um prognóstico pouco favorável quando comparados com cancros detetados em estadios menos avançados, daí a importância de um diagnóstico precoce. O estadio determina a escolha de tratamento e representa a severidade do tumor, o que influenciará o tempo de sobrevivênia. A classificação TNM é um sistema de estadios criado com base em três critérios de informação: o tamanho do tumor primário (T), extensão para os nódulos linfáticos vizinhos (N) e extensão para orgãos distantes (M). De acordo com os exames de diagnóstico, a doença pode ser classificada como I, II, IIIA, IIIB or IV, sendo um indicador da severidade da doença. A nova campanha , Treatment for All, da União para o Controlo Internacional do Cancro tem como objetivo reduzir a morte prematura de cancro e promove o acesso equitativo para o tratamento e bem-estar. As condições socioeconómicas são alguns dos fatores que podem comprometer o acesso aos cuidados de saúde. Portanto, o principal objetivo deste estudo foi perceber se os fatores socioeconómicos e o acesso aos cuidados de saúde estão associados com o estadio em que o cancro é diagnosticado. A informação foi recolhida pelo Registo Oncológico Regional Sul (ROR-Sul), que inclui as regiões de Lisboa e Vale do Tejo, Alentejo, Algarve e Região Autónoma da Madeira. O conjunto de dados tinha incluído 2266 pacientes diagnosticados com cancro do pulmão em 2013 e 2014. As variáveis incluídas foram o género, idade, concelho de residência, distrito de residência, morfologia, lateralidade, estadio ao diagnóstico e estado vital. As variáveis socioeconómicas foram extraídas a partir do INE e PORDATA. Através da revisão de literatura, foram identificados alguns indicadores que caraterizam as condições socioeconómicas, bem como as de acesso aos cuidados de saúde. Os dados foram modelados aplicando o modelo de regressão ordinal e o modelo misto de regressão ordinal, usando o concelho de residência como um efeito aleatório, que corresponde à variável que liga o conjunto de dados originais aos indicadores socioeconómicos e de acesso aos cuidados de saúde. O termo aleatório explicará as diferenças entre os concelhos e reduz a componente por explicar do modelo sem um termo aleatório. A correlação linear foi analisada para evitar a inclusão de variáveis independentes fortemente correlacionadas. A variável escolhida entre o par fortemente correlacionado era a mais informativa, excluindo aquela que, sendo menos informativa, estava associada à que foi incluída. A influência de cada uma das variáveis foi analisado de acordo com o odds ratio (OR). Considerando o sinal dos coeficientes de regressão, os resultados do modelo múltiplo sem termo aleatório indicaram que maior número de médicos por cada 1000 habitantes (OR 0.974, 95% CI: 0.942 - 1.008), idades avançadas (OR 0.996, 95% CI: 0.989 - 1.004) e maior número de beneficiários por cada 1000 habitantes (OR 0.998, 95% CI: 0.993 - 1.004) aparentam favorecer estadios mais baixos. Um maior rendimento anual (OR 1.003, 95% CI: 0.949 - 1.060) e um maior número de atendimentos por cada 1000 habitantes (OR 1.005, 95% CI: 0.995 - 1.016), aparentam contribuir para um diagnóstico em estadios avançados. O impacto do género variou de acordo com a categoria da variável resposta. Incluindo o termo aleatório, os resultados também indicaram que um elevado número de médicos por cada 1000 habitantes (OR 0.971, 95% CI: 0.880 - 1.073), uma idade avançada (OR 0.996, 95% CI: 0.988- 1.004) e um maior número de beneficiários por cada 1000 habitantes (OR 0.998, 95% CI: 0.988 - 1.009) aparentam favorecer estadios menos avançados. Um elevado rendimento anual (OR 1.008, 95% CI: 0.942 - 1.078) e um maior número de atendimentos por cada 1000 habitantes (OR 1.007, 95% CI: 0.988 - 1.026) aparentam contribuir para um diagnóstico em estadios avançados. Ao contrário do modelo sem termo aleatório, o efeito do género não varia de acordo com a severidade da doença. Com base no sinal do seu coeficiente de regressão, a possibilidade de um homem ser diagnosticado num estadio avançado era menor que uma mulher (OR 0.866 , 95% CI: 0.572 - 1.312). Apesar da variância associada ao termo aleatório (concelho de residência) tenha sido próxima de 1, a diferença entre estas regiões foram estatisticamente significativas no que diz respeito à severidade do estadio ao diagnóstico. A análise geoespacial mostrou que uma região do Centro tinha menor possibilidade de diagnóstico em estadios superiores. Na Região Autónoma da Madeira, a possibilidade de diagnóstico em estadios superiores era maior. Os resultados dos modelos múltiplos não encontraram evidências de associação entre as condições socioeconómicas e o acesso aos cuidados de saúde e a severidade do cancro do pulmão. O trabalho futuro deve passar pela recolha de mais informações individuais sobre o paciente, como estado civil, hábitos tabágicos, alimentção, mas também condições económicas e de acesso aos cuidados de saúde, como ter médico de família, proximidade de centros de saúde, facilidade para sair do trabalho, cobertura de seguro, etc.
Lung cancer is the most lethal type of cancer worldwide. The estimates for Portugal in 2018 indicate that 4671 individuals died of lung cancer, corresponding to 16.1% of total cancer deaths, with 5284 new cases estimated per year, corresponding to 9.1% of all cancers. The incidence rate for males is 38.8 per 100000 inhabitants whereas for females is 12.6 per 100000 inhabitants, which corresponds to an 75% increase. The high mortality rate of this type of cancer can be attributed to the fact that it is an asymptomatic disease, which delays diagnosis. Cancers in more advanced stages have reduced favourable prognosis compared to cancers detected in earlier stages, hence the importance of early diagnosis. The stage determines the choice of treatment and represents the severity of the tumour, which will influence survival time. TNM classification is a staging system created based on three information criteria: the size of the primary tumor (T), the spread to nearby lymph nodes (N) and the spread to distant organs (M). According to the diagnostic exams, the disease can be classified as I, II, IIIA, IIIB or IV, being an indicator of the severity of the disease. The new campaign, Treatment for All, of the Union for International Cancer Control (UICC) aims to reduce premature mortality from cancer and promote equitable access to treatment and care. Socioeconomic conditions can compromise access to primary health care. Therefore, the main aim of this study was to understand if socioeconomic factors and access to primary health care are associated with the stage at which the cancer is diagnosed. Data were collected from the Southern Portugal Cancer Registry (ROR-Sul), which includes the regions of Lisbon and the Tagus Valley, Alentejo, Algarve and Autonomous Region of Madeira. The dataset had included 2266 patients diagnosed with lung cancer in 2013 and 2014. The variables included in the original dataset were gender, age, residence county, residence district, morphology, laterality, stage at diagnosis and vital status. Socioeconomic variables were downloaded from the INE and PORDATA. Through a literature review several indicators characterizing the socioeconomic conditions as well as the access to healthcare conditions were identified. The data were modelled applying the ordinal regression model and the ordinal regression mixed model using the residence county as a random effect, which corresponds to the variable that links the original dataset to the socioeconomic and access healthcare indicators. The random term will explain the differences between counties and reduce the unexplained component of the model without a random term. The linear correlation was analysed to avoid the inclusion of strongly correlated independent variables. The variable chosen among the strongly correlated pair was the most informative, excluding the one that, being less informative, was associated with the one that was included. The influence of each variable was analysed according to the odds ratio (OR). Considering the sign of the regression coefficients, the results of the multivariable model without random term indicated that higher number of doctors per 1000 inhabitants (OR 0.974, 95% CI: 0.942 - 1.008), higher age (OR 0.996, 95% CI: 0.989 - 1.004) and higher number of welfare recipients per 1000 inhabitants (OR 0.998, 95% CI: 0.993 - 1.004) appeared as favouring lower stages. A higher annual income (OR 1.003, 95% CI: 0.949 - 1.060) and a higher number of attendances per 1000 inhabitants (OR 1.005, 95% CI: 0.995 - 1.016), appeared as contributing to a diagnosis in higher stages. The impact of gender varied according to the category. Including the random term, the results also indicated that a higher number of doctors per 1000 inhabitants (OR 0.971, 95% CI: 0.880 - 1.073), a higher age (OR 0.996, 95% CI: 0.988 - 1.004) and a higher number of welfare recipients per 1000 inhabitants (OR 0.998, 95% CI: 0.988 - 1.009) appeared favouring lower stages. A higher annual income (OR 1.008, 95% CI: 0.942 - 1.078) and a higher number of attendances per 1000 inhabitants (OR 1.007, 95% CI: 0.988 - 1.026), appeared as contributing to a diagnosis in higher stages. Unlike the model with no random term, the effect of gender does not vary according to the severity of the disease. Based on the sign of its regression coefficient, the odds of a male being diagnosed at a later stage was less than a woman (OR 0.866, 95% CI: 0.572 - 1.312). Although the variance associated with the random effect (residence county) was close to 1, the difference within regions were statistically significant regarding the severity of stage at diagnosis. The geospatial analysis has shown that a region in the Center had a lower possibility of having a diagnosis at higher stages. In the Autonomous Region of Madeira, the possibility of having a diagnosis at higher stages was higher. The multivariable models results found no evidence of a statistically significant association between socioeconomic conditions and access to healthcare, as they were measured, and lung cancer severity. Future work should collect more individual information about the patient, such as marital status, smoking habits, diet, but also economic conditions and conditions accessing healthcare, such as having a family doctor, proximity to health centres, ease of leaving work, insurance coverage, etc.
6
Dong, Bin. "Empirical Likelihood Method for Ratio Estimation". Thesis, 2011. http://hdl.handle.net/10012/5817.
Abstract (sommario):
Empirical likelihood, which was pioneered by Thomas and Grunkemeier (1975)
and Owen (1988), is a powerful nonparametric method of statistical inference that
has been widely used in the statistical literature. In this thesis, we investigate the
merits of empirical likelihood for various problems arising in ratio estimation. First,
motivated by the smooth empirical likelihood (SEL) approach proposed by Zhou &
Jing (2003), we develop empirical likelihood estimators for diagnostic test likelihood
ratios (DLRs), and derive the asymptotic distributions for suitable likelihood ratio
statistics under certain regularity conditions. To skirt the bandwidth selection problem
that arises in smooth estimation, we propose an empirical likelihood estimator
for the same DLRs that is based on non-smooth estimating equations (NEL). Via
simulation studies, we compare the statistical properties of these empirical likelihood
estimators (SEL, NEL) to certain natural competitors, and identify situations
in which SEL and NEL provide superior estimation capabilities.
Next, we focus on deriving an empirical likelihood estimator of a baseline cumulative
hazard ratio with respect to covariate adjustments under two nonproportional
hazard model assumptions. Under typical regularity conditions, we show
that suitable empirical likelihood ratio statistics each converge in distribution to a
2 random variable. Through simulation studies, we investigate the advantages of
this empirical likelihood approach compared to use of the usual normal approximation.
Two examples from previously published clinical studies illustrate the use of
the empirical likelihood methods we have described.
Empirical likelihood has obvious appeal in deriving point and interval estimators
for time-to-event data. However, when we use this method and its asymptotic
critical value to construct simultaneous confidence bands for survival or cumulative
hazard functions, it typically necessitates very large sample sizes to achieve reliable
coverage accuracy. We propose using a bootstrap method to recalibrate the critical
value of the sampling distribution of the sample log-likelihood ratios. Via simulation
studies, we compare our EL-based bootstrap estimator for the survival function
with EL-HW and EL-EP bands proposed by Hollander et al. (1997) and apply this
method to obtain a simultaneous confidence band for the cumulative hazard ratios
in the two clinical studies that we mentioned above.
While copulas have been a popular statistical tool for modeling dependent data
in recent years, selecting a parametric copula is a nontrivial task that may lead to
model misspecification because different copula families involve different correlation
structures. This observation motivates us to use empirical likelihood to estimate
a copula nonparametrically. With this EL-based estimator of a copula, we derive
a goodness-of-fit test for assessing a specific parametric copula model. By means
of simulations, we demonstrate the merits of our EL-based testing procedure. We
demonstrate this method using the data from Wieand et al. (1989).
In the final chapter of the thesis, we provide a brief introduction to several areas
for future research involving the empirical likelihood approach.
Libri sul tema "Cumulative diagnosis":
1
MacLoughlin, P. V. A. Understanding and treating RSI. London: Chelsea Press, 2005.
2
Keats, Theodore E. Radiology of musculoskeletal stress injury. Chicago: Year Book Medical Publishers, 1990.
3
Vern, Putz-Anderson, a cura di. Cumulative trauma disorders: A manual for musculoskeletal diseases of the upper limbs. London: Taylor & Francis, 1988.
4
Andrew, Chalmers, e Physical Medicine Research Foundation. International Symposium, a cura di. Fibromyalgia, chronic fatigue syndrome, and repetitive strain injury: Current concepts in diagnosis, management, disability, and health economics. New York: Haworth Medical Press, 1995.
5
Pećina, Marko. Overuse injuries of the musculoskeletal system. Boca Raton, FL: CRC Press, 1993.
6
Pećina, Marko. Overuse injuries of the musculoskeletal system. 2a ed. Boca Raton, Fla: CRC Press, 2004.
7
Pascarelli, Emil F. Repetitive strain injury: A computer user's guide. New York: J. Wiley, 1994.
8
1947-, Tehranzadeh Jamshid, Serafini Aldo N e Pais M. Joyce, a cura di. Avulsion and stress injuries of the musculoskeletal system. Basel: Karger, 1989.
9
Putz-Anderson, Vern. Cumulative Trauma Disorders. Taylor & Francis Group, 2017.
10
Gürsoy, Ulvi Kahraman, e Eija Könönen, a cura di. Use of Saliva in Diagnosis of Periodontitis: Cumulative Use of Bacterial and Host-Derived Biomarkers. Frontiers Media SA, 2017. http://dx.doi.org/10.3389/978-2-88945-124-1.
Capitoli di libri sul tema "Cumulative diagnosis":
1
Seow-En, Isaac, Yuan-Yao Tsai e William Tzu-Liang Chen. "Laparoscopic Parastomal Hernia Repair". In Mastering Endo-Laparoscopic and Thoracoscopic Surgery, 489–95. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-3755-2_68.
Abstract (sommario):
AbstractParastomal hernia is an incisional hernia resulting from an abdominal wall stoma creation [1]. The published incidence of parastomal hernia varies widely, with 2–28% and 4–48% affecting end ileostomies and end colostomies, respectively, depending on the severity of the hernia, method of diagnosis, and the duration of follow-up [2]. Loop stomas have a much lower incidence of parastomal herniation, as these tend to be reversed before a hernia can develop. The risk of herniation is cumulative with time but appears to be highest within 2 years of ostomy formation. Most patients are asymptomatic or have mild complaints such as intermittent discomfort or sporadic obstructive symptoms, but many eventually have symptoms significant enough to warrant surgical intervention, including incarceration, strangulation, and perforation. The bulging around the stoma can also cause result in difficulty applying the stoma appliance, resulting in leakage and skin irritation [2].
2
Malbrain, Manu L. N. G., Jonny Wilkinson, Luca Malbrain, Prashant Nasa e Adrian Wong. "Fluid Accumulation and Deresuscitation". In Rational Use of Intravenous Fluids in Critically Ill Patients, 495–526. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_25.
Abstract (sommario):
AbstractOverzealous fluid administration and capillary leaks may lead to overhydration or tissue edema. The deleterious effects of tissue edema involve disruption of tissue and endothelial glycocalyx, impeding capillary and lymphatic drainage, and causing cellular hypoxia and organ dysfunction. Evidence suggests that a progressive, cumulative positive fluid balance in patients with sepsis is an independent risk factor for organ failure and death. A combination of clinical, laboratory tests (such as hematocrit, brain natriuretic peptide, and serum electrolytes), radiological (point-of-care ultrasound or imaging) and advanced hemodynamic monitor may be used to diagnose and monitor overhydration. Various strategies to avoid and correct overhydration include fluid restriction and deresuscitation. Recent evidence supports the feasibility and safety of fluid restriction after initial resuscitation. Deresuscitation is defined as the active removal of excessive fluid using pharmacological or non-pharmacological measures and was coined during the 2011 International Fluid Academy meeting. A combination of diuretics, ultrafiltration, and fluid restriction, can be used for deresuscitation along with adequate monitoring to prevent hypoperfusion.
3
Wang, Wei, Francesco Di Maio e Enrico Zio. "A Non-parametric Cumulative Sum Approach for Online Diagnostics of Cyber Attacks to Nuclear Power Plants". In Resilience of Cyber-Physical Systems, 195–228. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-95597-1_9.
4
Nel, Kathryn, e Saraswathie Govender. "Cumulative Mild Head Injury (CMHI) in Contact Sports". In Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment. IntechOpen, 2019. http://dx.doi.org/10.5772/intechopen.80668.
5
Ipp, Eli, e Kristina Djekic. "Case 5: Recurrent Ketoacidosis: Lessons from Multiple Clinical Presentations". In Diabetes Case Studies: Real Problems, Practical Solutions, 15–18. American Diabetes Association, 2015. http://dx.doi.org/10.2337/9781580405713.05.
Abstract (sommario):
A 33-year-old Mexican American man presents to the emergency department (ED) with a history of nausea, abdominal pain, and weakness. Four months prior he was diagnosed with diabetes after complaints of polyuria, polydipsia, and anorexia. He was treated with glyburide but continued to experience symptoms. He reported a cumulative weight loss of 40 lb in the intervening months and arrived in the ED weighing 69.8 kg, with a BMI of 25 kg/m2. He is admitted to the hospital with a diagnosis of ketoacidosis.
6
Burns, Tom, e Mike Firn. "Substance abuse". In Assertive Outreach in Mental Health, 192–203. Oxford University PressOxford, 2002. http://dx.doi.org/10.1093/oso/9780198516156.003.0019.
Abstract (sommario):
Abstract Psychotic illnesses are increasingly complicated by alcohol and drug abuse as patients no longer spend long periods in hospital. Treated in the community the benefits of social inclusion can be offset by greater exposure to drugs and alcohol. Dual diagnosis patients will be used throughout this chapter to refer to patients with a psychotic illness plus significant alcohol or substance abuse. Assertive outreach provides the opportunity to accept dual diagnosis patients and work towards resolving the cumulative problems that both conditions bring. Dual diagnosis carries additional problems for both patients and services. Integrating both substance abuse strategies and more traditional mental health interventions in the same team is an essential response for such chaotic individuals.
7
Anthony, Marcus, Tejas Ozarkar, Juan Andres Moncayo e Shae Datta. "Pain and Youth Sports". In Pain Management in Vulnerable Populations, 458–73. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197649176.003.0030.
Abstract (sommario):
Abstract Pain in youth athletes is not synonymous with injury (tissue damage). Rather, youth athletes’ pain, be it nociceptive, neuropathic, or nociplastic, results from the cumulative impact of many biopsychosocial factors common to the youth athletic experience. Appropriate identification and correction of these factors is critical to optimal pain management in youth athletes, which should not be limited to the diagnosis and treatment of structural damage at the anatomic location of pain. This chapter provides a framework for the diagnosis and management of youth athletes’ pain that is informed by pain pathophysiology and biopsychosocial factors drawn from developmental, biomechanical, and psychosocial domains unique to the youth athlete.
8
O’Gradaigh, Donncha, e Brian Hazleman. "Work-Related Upper Limb Pain". In Oxford Medical Publications Soft Tissue Rheumatology, 523–29. Oxford University PressNew York, NY, 2004. http://dx.doi.org/10.1093/oso/9780192630933.003.0040.
Abstract (sommario):
Abstract Work-related musculoskeletal disorders comprise a heterogeneous group of conditions whose natural history is for the most part poorly understood. A variety of terms have been used in different ways. For some, ‘work-related upper limb disorders’, ‘cumulative trauma disorders’, and ‘repetitive strain disorders’ are synonymous and describe a range of conditions—some well defined, others less so—arising or appearing to arise from frequent overuse at work. For others, repetitive strain injury (RSI) refers to a particular diagnosis made by exclusion: chronic upper limb pain ascribed to overuse at work for which no clinical diagnosis can be made. The apparently simple question, ‘which musculoskeletal problems are work-related’, has proved difficult to answer. Study data are weakened by cross-sectional designs and by selection bias.
9
Jin, Yanrui, Zhiyuan Li, Yuanyuan Tian, Mengxiao Wang, Xiaoyang Wei, Chengliang Liu e Xiaoxue Yang. "ECG Quality Assessment Framework by Using Attentional Convolution Neural Network". In Fuzzy Systems and Data Mining IX. IOS Press, 2023. http://dx.doi.org/10.3233/faia231101.
Abstract (sommario):
ECG is an important means of diagnosis of arrhythmia. In daily health monitoring, serious noise pollution, reverse leads connection, and so on make cannot meet the requirements of subsequent automatic diagnosis. Thus, it is of great significance to further evaluate the ECG quality and screen out the ECG that meet the requirements of subsequent diagnosis. However, complex interference factors affect the quality of the signal and has brought the huge challenge to quality assessment. Additionally, the current algorithms depend on the wave detection, which also brings additional cumulative error. Meanwhile, the current algorithms cannot intuitively present the attention degree to ECG signals during the assessment process. This paper proposes a novel method (ACNN) for evaluating the ECG quality. ACNN directly targets the whole ECG signal and does not detect the waveform of the ECG signal. Then, ACNN uses convolutional blocks to extract the deep features and designs a novel attention layer to enhance the beneficial features of the results. Finally, the fully connected layer is employed for obtaining the final quality evaluation. Compared with existing methods, ACNN obtains better performance, with 100.0% sensitivity, 83.33% specificity and 98.0% accuracy, which shows ACNN can be applied in clinical scenarios.
10
Zulfikar, Rafia, e John E. Parker. "Coal Workers Pneumoconiosis". In Modern Occupational Diseases Diagnosis, Epidemiology, Management and Prevention, 74–103. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049138122010009.
Abstract (sommario):
Coal Worker’s Pneumoconiosis (CWP) was thought to be an archaic disease, but after an initial decline because of the Coal Mine Health and Safety Act in 1969, there has been a resurgence of this disease in the 21st century. For centuries, miners have been exposed to varied types and degrees of coal mine dust. Lung diseases in coal miners are caused by the inhalation, retention, and tissue reaction to the mixed constituents of this dust, which include carbon, silica, and silicates. Respirable dust particles of less than 5 microns are deposited in the proximal and distal airways and the smaller particles are deposited in the alveoli. The tissue reaction to these particles results in a variety of pathologic lesions, including coal macules, silicotic nodules, mixed dust pneumoconiosis, interstitial fibrosis, progressive massive fibrosis, bronchitis, and emphysema. These disorders are recognized primarily through occupational exposure history and characteristic radiographic imaging. With a latency of approximately 20 years, cumulative lifetime exposures appear to be most predictive of the disease severity. Prevention of these diseases should be the primary focus of the industry, the workforce, and the public health agencies. In the US, federal programs of screening and surveillance are in place and active. The treatment of these disorders as with other chronic respiratory conditions, is focused on vaccinations against respiratory infection, bronchodilator therapy when indicated, supplemental oxygen therapy when required, pulmonary rehabilitation programs, smoking cessation, vigilant observation for chronic respiratory infections, and if necessary, lung transplantation should be considered as the last resort.
Atti di convegni sul tema "Cumulative diagnosis":
1
Namba, Yasuhiro, Shunji Kato, Masami Iwai, Hiroshi Sato, Kentaroh Kokubun e Sotaro Masanobu. "Prediction of Cumulative Fatigue Damage of Mooring Dolphins". In ASME 2004 23rd International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2004. http://dx.doi.org/10.1115/omae2004-51362.
Abstract (sommario):
Very Large Floating Structures, so-called Mega-Floats, are the kind of social infrastructures. They are generally expected to keep their integrity for a long period, for example, more than 100 years. So, it is necessary to develop Long-Term Integrity Prediction and Diagnosis System to diagnose the soundness of Mega-Floats. In the present study, we paid our attention to dolphin-fender type mooring devices that pontoon type VLFS are equipped with. As a part of Long-Term Integrity Prediction and Diagnosis System, we developed a long-term integrity prediction code (Cumulative Fatigue Damage Prediction Code) to predict damage of these dolphins. We made an at-sea experiment with pontoon type VLFS model of 201.5 [m] length, 100 [m] breadth, and 3 [m] depth (We call this “At-Sea Experiment for Verifying Functions of Mega-Float Information Data Center”). The model had two dolphin-fender type mooring devices and we applied Cumulative Fatigue Damage Prediction Code to these devices.
2
Adjallah, Kondo H. "Cumulative diagnosis strategy for predictive maintenance decision support". In Industrial Engineering (CIE39). IEEE, 2009. http://dx.doi.org/10.1109/iccie.2009.5223731.
3
Lee, Juhun, Robert M. Nishikawa e Gustavo K. Rohde. "Detecting mammographically occult cancer in women with dense breasts using Radon Cumulative Distribution Transform: a preliminary analysis". In Computer-Aided Diagnosis, a cura di Kensaku Mori e Nicholas Petrick. SPIE, 2018. http://dx.doi.org/10.1117/12.2293541.
4
Lee, Juhun, e Robert M. Nishikawa. "Detecting mammographically-occult cancer in women with dense breasts using deep convolutional neural network and Radon cumulative distribution transform". In Computer-Aided Diagnosis, a cura di Horst K. Hahn e Kensaku Mori. SPIE, 2019. http://dx.doi.org/10.1117/12.2512446.
5
Lee, Juhun, Federico Pineda, Gregory S. Karczmar, Robert M. Nishikawa e Hiroyuki Abe. "Breast lesion detection scheme for low gadolinium dose DCE-MRI using radon cumulative distribution transform and domain transfer: preliminary results". In Computer-Aided Diagnosis, a cura di Susan M. Astley e Weijie Chen. SPIE, 2024. http://dx.doi.org/10.1117/12.3004216.
6
Qin, Shao-Rui, Yu-Hang Fang, Guo-Cheng Ding, Tai-Yun Zhu, Jian-Lin Li, Chen-Chen Zhang e Guan-Jun Zhang. "Partial Discharge Identification of Power Transformers Based on Chaotic Characteristics of the Cumulative Energy Function". In 2018 Condition Monitoring and Diagnosis (CMD). IEEE, 2018. http://dx.doi.org/10.1109/cmd.2018.8535653.
7
Lee, Juhun, Robert M. Nishikawa, Andriy Bandos e Margarita Zuley. "Estimating near term breast cancer risk from sequential mammograms using deep learning, radon cumulative distribution transform, and a clinical risk factor: preliminary analysis". In Computer-Aided Diagnosis, a cura di Karen Drukker e Maciej A. Mazurowski. SPIE, 2021. http://dx.doi.org/10.1117/12.2580941.
8
Shi, Zhen, e Peter Sandborn. "Modeling Test, Diagnosis, and Rework Operations and Optimizing Their Location in General Manufacturing Processes". In ASME 2003 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/detc2003/dfm-48145.
Abstract (sommario):
This paper presents a test, diagnosis, and rework analysis model for use in manufacturing process modeling. The approach includes a model of functional test operations characterized by fault coverage, false positives, and defects introduced in test, in addition to rework and diagnosis (diagnostic test) operations that have variable success rates and their own defect introduction mechanisms. The model accommodates multiple rework attempts on a product instance. The model is applied within a framework for optimizing the location(s) and characteristics (fault coverage/test cost, rework success rate/rework cost) of Test/Diagnosis/Rework (TDR) operations in a general manufacturing process. A new search algorithm called Waiting Sequence Search (WSS) is applied to traverse a general process flow to perform the cumulative calculation of a yielded cost objective function. Real-Coded Genetic Algorithms (RCGAs) are used to perform a multi-objective optimization that minimizes yielded cost. An example of a general complex process flow is used to demonstrate the feasibility of the algorithm.
9
Eom, Ju-Hong, Hyeon-Sang Ko, Tae-Ho Choi e Ji-Won Kang. "Accelerated Life Estimation of XLPE Model Cable for Power Transmission by the Time Dependent Cumulative Stress Level". In 2022 9th International Conference on Condition Monitoring and Diagnosis (CMD). IEEE, 2022. http://dx.doi.org/10.23919/cmd54214.2022.9991456.
10
Sampath, Suresh, Y. G. Li, S. O. T. Ogaji e Riti Singh. "Fault Diagnosis of a Two Spool Turbo-Fan Engine Using Transient Data: A Genetic Algorithm Approach". In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38300.
Abstract (sommario):
Traditionally engine fault diagnosis has been performed at steady state conditions. There are several problems which can only be detected by transient data analysis like bearing fault, some control problems etc.. In addition, gas turbine performance deviation due to a component fault is more likely to be magnified during transients, when compared with the same parameter deviations at steady states. The specific approach used in this paper is to compare model-based information with measured data obtained from the engine during a slam acceleration. The measured transient data (from actual engine) is compared with a set of simulated data from the engine transient model, under similar operating conditions and known faults through a Cumulative Deviation. The Cumulative Deviations obtained from the comparisons are minimized for the best match using Genetic Algorithm. The Genetic Algorithm has been tailored to use real coding [1] method and to meet the requirements of the new procedure. The paper describes the application of the approach to a 2-spool turbofan engine and discusses the preliminary studies conducted.
Rapporti di organizzazioni sul tema "Cumulative diagnosis":
1
Svetlov, Stanislav, Ronald Hayes e Olena Glushakova. Molecular Signatures and Diagnostic Biomarkers of Cumulative Blast-Graded Mild TBI. Fort Belvoir, VA: Defense Technical Information Center, dicembre 2014. http://dx.doi.org/10.21236/ada612707.
2
Svetlov, Stanislav. Molecular Signatures and Diagnostic Biomarkers of Cumulative, Blast-Graded Mild TBI. Fort Belvoir, VA: Defense Technical Information Center, ottobre 2012. http://dx.doi.org/10.21236/ada582352.
3
Newman-Toker, David E., Susan M. Peterson, Shervin Badihian, Ahmed Hassoon, Najlla Nassery, Donna Parizadeh, Lisa M. Wilson et al. Diagnostic Errors in the Emergency Department: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), dicembre 2022. http://dx.doi.org/10.23970/ahrqepccer258.
Abstract (sommario):
Objectives. Diagnostic errors are a known patient safety concern across all clinical settings, including the emergency department (ED). We conducted a systematic review to determine the most frequent diseases and clinical presentations associated with diagnostic errors (and resulting harms) in the ED, measure error and harm frequency, as well as assess causal factors. Methods. We searched PubMed®, Cumulative Index to Nursing and Allied Health Literature (CINAHL®), and Embase® from January 2000 through September 2021. We included research studies and targeted grey literature reporting diagnostic errors or misdiagnosis-related harms in EDs in the United States or other developed countries with ED care deemed comparable by a technical expert panel. We applied standard definitions for diagnostic errors, misdiagnosis-related harms (adverse events), and serious harms (permanent disability or death). Preventability was determined by original study authors or differences in harms across groups. Two reviewers independently screened search results for eligibility; serially extracted data regarding common diseases, error/harm rates, and causes/risk factors; and independently assessed risk of bias of included studies. We synthesized results for each question and extrapolated U.S. estimates. We present 95 percent confidence intervals (CIs) or plausible range (PR) bounds, as appropriate. Results. We identified 19,127 citations and included 279 studies. The top 15 clinical conditions associated with serious misdiagnosis-related harms (accounting for 68% [95% CI 66 to 71] of serious harms) were (1) stroke, (2) myocardial infarction, (3) aortic aneurysm and dissection, (4) spinal cord compression and injury, (5) venous thromboembolism, (6/7 – tie) meningitis and encephalitis, (6/7 – tie) sepsis, (8) lung cancer, (9) traumatic brain injury and traumatic intracranial hemorrhage, (10) arterial thromboembolism, (11) spinal and intracranial abscess, (12) cardiac arrhythmia, (13) pneumonia, (14) gastrointestinal perforation and rupture, and (15) intestinal obstruction. Average disease-specific error rates ranged from 1.5 percent (myocardial infarction) to 56 percent (spinal abscess), with additional variation by clinical presentation (e.g., missed stroke average 17%, but 4% for weakness and 40% for dizziness/vertigo). There was also wide, superimposed variation by hospital (e.g., missed myocardial infarction 0% to 29% across hospitals within a single study). An estimated 5.7 percent (95% CI 4.4 to 7.1) of all ED visits had at least one diagnostic error. Estimated preventable adverse event rates were as follows: any harm severity (2.0%, 95% CI 1.0 to 3.6), any serious harms (0.3%, PR 0.1 to 0.7), and deaths (0.2%, PR 0.1 to 0.4). While most disease-specific error rates derived from mainly U.S.-based studies, overall error and harm rates were derived from three prospective studies conducted outside the United States (in Canada, Spain, and Switzerland, with combined n=1,758). If overall rates are generalizable to all U.S. ED visits (130 million, 95% CI 116 to 144), this would translate to 7.4 million (PR 5.1 to 10.2) ED diagnostic errors annually; 2.6 million (PR 1.1 to 5.2) diagnostic adverse events with preventable harms; and 371,000 (PR 142,000 to 909,000) serious misdiagnosis-related harms, including more than 100,000 permanent, high-severity disabilities and 250,000 deaths. Although errors were often multifactorial, 89 percent (95% CI 88 to 90) of diagnostic error malpractice claims involved failures of clinical decision-making or judgment, regardless of the underlying disease present. Key process failures were errors in diagnostic assessment, test ordering, and test interpretation. Most often these were attributed to inadequate knowledge, skills, or reasoning, particularly in “atypical” or otherwise subtle case presentations. Limitations included use of malpractice claims and incident reports for distribution of diseases leading to serious harms, reliance on a small number of non-U.S. studies for overall (disease-agnostic) diagnostic error and harm rates, and methodologic variability across studies in measuring disease-specific rates, determining preventability, and assessing causal factors. Conclusions. Although estimated ED error rates are low (and comparable to those found in other clinical settings), the number of patients potentially impacted is large. Not all diagnostic errors or harms are preventable, but wide variability in diagnostic error rates across diseases, symptoms, and hospitals suggests improvement is possible. With 130 million U.S. ED visits, estimated rates for diagnostic error (5.7%), misdiagnosis-related harms (2.0%), and serious misdiagnosis-related harms (0.3%) could translate to more than 7 million errors, 2.5 million harms, and 350,000 patients suffering potentially preventable permanent disability or death. Over two-thirds of serious harms are attributable to just 15 diseases and linked to cognitive errors, particularly in cases with “atypical” manifestations. Scalable solutions to enhance bedside diagnostic processes are needed, and these should target the most commonly misdiagnosed clinical presentations of key diseases causing serious harms. New studies should confirm overall rates are representative of current U.S.-based ED practice and focus on identified evidence gaps (errors among common diseases with lower-severity harms, pediatric ED errors and harms, dynamic systems factors such as overcrowding, and false positives). Policy changes to consider based on this review include: (1) standardizing measurement and research results reporting to maximize comparability of measures of diagnostic error and misdiagnosis-related harms; (2) creating a National Diagnostic Performance Dashboard to track performance; and (3) using multiple policy levers (e.g., research funding, public accountability, payment reforms) to facilitate the rapid development and deployment of solutions to address this critically important patient safety concern.