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1

Kamińska, Halla, Paweł Wieczorek, Eliza Skała-Zamorowska, Grażyna Deja e Przemysława Jarosz-Chobot. "Dysglycemia in critically ill children". Pediatric Endocrinology Diabetes and Metabolism 22, n. 1 (2016): 21–25. http://dx.doi.org/10.18544/pedm-22.01.0046.

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Tyrrell, Cornelius T., e Scot T. Bateman. "Critically ill children". Pediatric Critical Care Medicine 13, n. 2 (marzo 2012): 204–9. http://dx.doi.org/10.1097/pcc.0b013e318219291c.

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3

Fortune, Peter-Marc, e Stephen Playfor. "Transporting critically ill children". Anaesthesia & Intensive Care Medicine 10, n. 10 (ottobre 2009): 510–13. http://dx.doi.org/10.1016/j.mpaic.2008.10.004.

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Fortune, Peter-Marc, Kate Parkins e Stephen Playfor. "Transporting critically ill children". Anaesthesia & Intensive Care Medicine 15, n. 12 (dicembre 2014): 577–80. http://dx.doi.org/10.1016/j.mpaic.2014.09.001.

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Fortune, Peter-Marc, Kate Parkins e Stephen Playfor. "Transporting critically ill children". Anaesthesia & Intensive Care Medicine 18, n. 11 (novembre 2017): 562–66. http://dx.doi.org/10.1016/j.mpaic.2017.08.002.

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6

Harvey, Matthew, Sarah Edmunds e Arun Ghose. "Transporting critically ill children". Anaesthesia & Intensive Care Medicine 21, n. 12 (dicembre 2020): 641–48. http://dx.doi.org/10.1016/j.mpaic.2020.10.011.

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7

Foster, Jennifer. "Melatonin in Critically Ill Children". Journal of Pediatric Intensive Care 05, n. 04 (28 aprile 2016): 172–81. http://dx.doi.org/10.1055/s-0036-1583283.

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AbstractMelatonin, while best known for its chronobiologic functions, has multiple effects that may be relevant in critical illness. It has been used for circadian rhythm maintenance, analgesia, and sedation, and has antihypertensive, anti-inflammatory, antioxidant, antiapoptotic, and antiexcitatory effects. This review examines melatonin physiology in health, the current state of knowledge regarding endogenous melatonin production in pediatric critical illness, and the potential uses of exogenous melatonin in this population, including relevant information from basic sciences and other fields of medicine. Pineal melatonin production and secretion appears to be altered in critical illness, though understanding in pediatric critical illness is in early stages, with only 102 children reported in the current literature. Exogenous melatonin may be used for circadian rhythm disturbances and, within the critically ill population, holds promise for diseases involving oxidant stress. There are no studies of exogenous melatonin administration to critically ill children beyond the neonatal period.
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Yalcinkaya, Asli, Hakan Tekguc e Oguz Dursun. "Rhabdomyolysis in Critically ill Children". Turkish Journal of Pediatric Emergency and Intensive Care Medicine 1, n. 2 (2014): 61–64. http://dx.doi.org/10.5505/cayb.2014.03522.

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9

Millichap, J. Gordon. "Myopathy in Critically Ill Children". Pediatric Neurology Briefs 18, n. 2 (1 febbraio 2004): 11. http://dx.doi.org/10.15844/pedneurbriefs-18-2-3.

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10

Menezes, Fernanda Souza de, Heitor Pons Leite, Juliana Fernandez, Silvana Gomes Benzecry e Werther Brunow de Carvalho. "Hypophosphatemia in critically ill children". Revista do Hospital das Clínicas 59, n. 5 (2004): 306–11. http://dx.doi.org/10.1590/s0041-87812004000500015.

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Abstract (sommario):
The purpose of this paper is to review clinical studies on hypophosphatemia in pediatric intensive care unit patients with a view to verifying prevalence and risk factors associated with this disorder. We searched the computerized bibliographic databases Medline, Embase, Cochrane Library, and LILACS to identify eligible studies. Search terms included critically ill, pediatric intensive care, trauma, sepsis, infectious diseases, malnutrition, inflammatory response, surgery, starvation, respiratory failure, diuretic, steroid, antiacid therapy, mechanical ventilation. The search period covered those clinical trials published from January 1990 to January 2004. Studies concerning endocrinological disorders, genetic syndromes, rickets, renal diseases, anorexia nervosa, alcohol abuse, and prematurity were not included in this review. Out of 27 studies retrieved, only 8 involved pediatric patients, and most of these were case reports. One clinical trial and one retrospective study were identified. The prevalence of hypophosphatemia exceeded 50%. The commonly associated factors in most patients with hypophosphatemia were refeeding syndrome, malnutrition, sepsis, trauma, and diuretic and steroid therapy. Given the high prevalence, clinical manifestations, and multiple risk factors, the early identification of this disorder in critically ill children is crucial for adequate replacement therapy and also to avoid complications.
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11

Bratton, S. L. "Transfusions in Critically Ill Children". AAP Grand Rounds 18, n. 1 (1 luglio 2007): 2–3. http://dx.doi.org/10.1542/gr.18-1-2.

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Roumeliotis, Nadia, e Jacques Lacroix. "Bleeding in Critically Ill Children". Pediatric Critical Care Medicine 20, n. 7 (luglio 2019): 674–75. http://dx.doi.org/10.1097/pcc.0000000000001959.

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Gaetani, Melany, Helena Frndova, Winnie Seto e Christopher Parshuram. "Pharmacotherapy in Critically Ill Children". Pediatric Critical Care Medicine 21, n. 4 (aprile 2020): e170-e176. http://dx.doi.org/10.1097/pcc.0000000000002236.

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14

Parker, Robert I. "Transfusion in Critically Ill Children". Critical Care Medicine 42, n. 3 (marzo 2014): 675–90. http://dx.doi.org/10.1097/ccm.0000000000000176.

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15

Traube, Chani, Gabrielle Silver, Ron W. Reeder, Hannah Doyle, Emily Hegel, Heather A. Wolfe, Christopher Schneller et al. "Delirium in Critically Ill Children". Critical Care Medicine 45, n. 4 (aprile 2017): 584–90. http://dx.doi.org/10.1097/ccm.0000000000002250.

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Moreno, Yara Maria Franco, Julia Carvalho Ventura, Luna Dias de Almeida Oliveira, Taís Thomsen Silveira e Daniela Barbieri Hauschild. "Undernutrition in critically ill children". Pediatric Medicine 3 (novembre 2020): 22. http://dx.doi.org/10.21037/pm-20-66.

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Playfor, S. D., e H. Vyas. "Sedation in critically ill children". Current Paediatrics 10, n. 1 (marzo 2000): 1–4. http://dx.doi.org/10.1054/cupe.2000.0070.

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18

Sideri, G., D. A. Kafetzis, E. K. Vouloumanou, J. H. Papadatos, M. Papadimitriou e M. E. Falagas. "Ciprofloxacin in Critically Ill Children". Anaesthesia and Intensive Care 39, n. 4 (luglio 2011): 635–39. http://dx.doi.org/10.1177/0310057x1103900416.

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19

Faustino, E. Vincent S., Eliotte L. Hirshberg e Clifford W. Bogue. "Hypoglycemia in Critically Ill Children". Journal of Diabetes Science and Technology 6, n. 1 (gennaio 2012): 48–57. http://dx.doi.org/10.1177/193229681200600107.

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20

Bowlby, Deborah, Robert Rapaport e Joanne Hojsak. "Hyperglycemia in critically ill children". Journal of Pediatrics 148, n. 6 (giugno 2006): 847. http://dx.doi.org/10.1016/j.jpeds.2005.06.012.

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21

Cardenas-Rivero, Nicolas, Bart Chernow, Michael A. Stoiko, Samuel R. Nussbaum e I. David Todres. "Hypocalcemia in critically ill children". Journal of Pediatrics 114, n. 6 (giugno 1989): 946–51. http://dx.doi.org/10.1016/s0022-3476(89)80435-4.

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22

Singhi, Sunit C., e Suresh Kumar. "Probiotics in critically ill children". F1000Research 5 (29 marzo 2016): 407. http://dx.doi.org/10.12688/f1000research.7630.1.

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Abstract (sommario):
Gut microflora contribute greatly to immune and nutritive functions and act as a physical barrier against pathogenic organisms across the gut mucosa. Critical illness disrupts the balance between host and gut microflora, facilitating colonization, overgrowth, and translocation of pathogens and microbial products across intestinal mucosal barrier and causing systemic inflammatory response syndrome and sepsis. Commonly used probiotics, which have been developed from organisms that form gut microbiota, singly or in combination, can restore gut microflora and offer the benefits similar to those offered by normal gut flora, namely immune enhancement, improved barrier function of the gastrointestinal tract (GIT), and prevention of bacterial translocation. Enteral supplementation of probiotic strains containing either Lactobacillus alone or in combination with Bifidobacterium reduced the incidence and severity of necrotizing enterocolitis and all-cause mortality in preterm infants. Orally administered Lactobacillus casei subspecies rhamnosus, Lactobacillus reuteri, and Lactobacillus rhamnosus were effective in the prevention of late-onset sepsis and GIT colonization by Candida in preterm very low birth weight infants. In critically ill children, probiotics are effective in the prevention and treatment of antibiotic-associated diarrhea. Oral administration of a mix of probiotics for 1 week to children on broad-spectrum antibiotics in a pediatric intensive care unit decreased GIT colonization by Candida, led to a 50% reduction in candiduria, and showed a trend toward decreased incidence of candidemia. However, routine use of probiotics cannot be supported on the basis of current scientific evidence. Safety of probiotics is also a concern; rarely, probiotics may cause bacteremia, fungemia, and sepsis in immunocompromised critically ill children. More studies are needed to answer questions on the effectiveness of a mix versus single-strain probiotics, optimum dosage regimens and duration of treatment, cost effectiveness, and risk-benefit potential for the prevention and treatment of various critical illnesses.
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23

Lacroix, Jacques, e Baruch Toledano. "Erythropoietin for critically ill children *". Pediatric Critical Care Medicine 4, n. 1 (gennaio 2003): 123–24. http://dx.doi.org/10.1097/00130478-200301000-00029.

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24

Faustino, E. VS, e M. Apkon. "Hyperglycemia in Critically Ill Children". Pediatric Critical Care Medicine 6, n. 1 (gennaio 2005): 107. http://dx.doi.org/10.1097/00130478-200501000-00073.

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25

Shankar, Poornima, e Saipraneeth Reddy Guda. "HYPOPHOSPHATAEMIA IN CRITICALLY ILL CHILDREN". Journal of Evolution of Medical and Dental Sciences 5, n. 53 (1 luglio 2016): 3480–82. http://dx.doi.org/10.14260/jemds/2016/803.

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26

Patki, Vinayak Krishnarao, e Swati Balasaheb Chougule. "Hyperglycemia in critically ill children". Indian Journal of Critical Care Medicine 18, n. 1 (gennaio 2014): 8–13. http://dx.doi.org/10.4103/0972-5229.125427.

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27

Shahsavari Nia, Kavous, Zahra Motazedi, Leila Mahmoudi, Fatemeh Ahmadi, Amir Ghafarzad e Amir Hossein Jafari-Rouhi. "Hypophosphatemia in critically ill children". Journal of Analytical Research in Clinical Medicine 4, n. 3 (10 settembre 2016): 153–57. http://dx.doi.org/10.15171/jarcm.2016.025.

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28

Trnka, P., J. Kralik, L. Pevalova, J. Tuharsky, T. Sagat, N. Hudecova, D. Krchova et al. "CANDIDURIA IN CRITICALLY ILL CHILDREN". Infectious Diseases in Clinical Practice 7, n. 5 (giugno 1998): 234–39. http://dx.doi.org/10.1097/00019048-199806000-00007.

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29

Hammer, Ju�rg. "Bronchoscopy in critically ill children". Pediatric Pulmonology 37, S26 (2004): 80–81. http://dx.doi.org/10.1002/ppul.70060.

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30

Horowitz, Ira N., e Kenneth Tai. "Hypoalbuminemia in Critically Ill Children". Archives of Pediatrics & Adolescent Medicine 161, n. 11 (1 novembre 2007): 1048. http://dx.doi.org/10.1001/archpedi.161.11.1048.

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31

Abro, Falak, Fozia Baloch, Mehtab Hussain, Asma Noreen, Nadeem Noor, Uzma Arshad e Bushra Rafique. "Vitamin D Deficiency in Critically Ill Children in Karachi". Pakistan Journal of Medical and Health Sciences 16, n. 3 (31 marzo 2022): 567–68. http://dx.doi.org/10.53350/pjmhs22163567.

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Abstract (sommario):
Objective: To evaluate vitamin D levels in critically ill children. Subject and methods: There were 114 critical ill patients, who were admitted in pediatric ICU with severe respiratory depression (sat < 90%), infection (WBC > 10X 103), myocarditis (EF < 40%). Blood sample was drawn for evaluation of vitamin D levels. Results:- The average age of the children was 4.95±2.7 years. There were 63(55.26%) male and 51(44.74%) female. Frequency of vitamin D deficiency in critically ill patients was observed in 55.26% (63/114) children. Conclusion: - In our study, critically ill children had higher frequency of vitamin D deficiency. Keywords: Vitamin D, Critically ill patients, Infection, 25(OH) D levels
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32

Fiore-Gartland, Andrew, Angela Panoskaltsis-Mortari, Anna A. Agan, Paul Glyndwr Thomas, Tomer Hertz e Adrienne Randolph. "Innate correlates of influenza clinical outcomes in a multicenter, longitudinal study of critically ill children". Journal of Immunology 196, n. 1_Supplement (1 maggio 2016): 124.35. http://dx.doi.org/10.4049/jimmunol.196.supp.124.35.

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Abstract Paradoxically, influenza infection can trigger pro- and anti-inflammatory responses, both of which can lead to significant morbidity and mortality. Inflammation can lead to septic shock and acute lung injury (ALI), while suppression can slow viral clearance and increase susceptibility to bacterial coinfection (BCo). We collected and analyzed lung and peripheral blood samples from a multi-center cohort of critically ill children with influenza infection (N = 171) to better understand innate signatures of disease. Samples were collected at admission to the PICU and assayed for levels of 42 cytokines and chemokines. We found intra-compartment analyte correlations were high, while those between compartments were comparatively weak. To increase statistical power and identify groups of co-signaling cytokines, we pre-specified an unsupervised hierarchical clustering analysis to form influenza-specific modules. Some modules were consistent with the literature; e.g. IL4, IL5, IL9 and IL13 (Th2-like) clustered within both compartments. We hypothesized that modules would associate with shock, ALI and death or near death (ECMO). A pro-inflammatory PB module including IL6, IL8, IL10, IP10, GCSF and MCP1 was associated with shock (FWER p&lt;1e-4; OR 3.4) and ALI (FWER p=0.003; OR 2.2), validating previous studies. Inverse associations were also identified with lung and serum modules, only after adjusting for patients’ mean analyte levels, suggesting that relative levels are important. An integrative analysis of lung and PB analytes showed that BCo has a distinct signature from shock that can be used as a biomarker to distinguish the two. Significant modules also generated hypotheses about analytes that could be targeted by novel therapies.
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Khilnani, Praveen, Nidhi Rawal e Chandrasekhar Singha. "Gastrointestinal Issues in Critically Ill Children". Indian Journal of Critical Care Medicine 24, S4 (2020): S201—S204. http://dx.doi.org/10.5005/jp-journals-10071-23637.

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34

Chang, Ikwan, Jae Yun Jung e Young Ho Kwak. "Interfacility transport of critically ill children". Pediatric Emergency Medicine Journal 4, n. 1 (30 giugno 2017): 1–4. http://dx.doi.org/10.22470/pemj.2017.00073.

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35

Incecik, Faruk, OzdenO Horoz, OzlemM Herguner, Dincer Yıldızdas, Seyda Besen, Ilknur Tolunay e Sakir Altunbasak. "Intravenous levetiracetam in critically ill children". Annals of Indian Academy of Neurology 19, n. 1 (2016): 79. http://dx.doi.org/10.4103/0972-2327.167702.

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36

Kandil, Sarah B., Prashant V. Mahajan e E. Vincent S. Faustino. "Vascular Access in Critically Ill Children". Pediatrics 145, Supplement 3 (giugno 2020): S296—S297. http://dx.doi.org/10.1542/peds.2019-3474o.

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37

Tran, Nga, Heather Clark, Cynthia Cupido, Daniel Corsi e Karen Choong. "Acute rehabilitation in critically ill children". Journal of Pediatric Intensive Care 01, n. 04 (28 luglio 2015): 183–92. http://dx.doi.org/10.3233/pic-12031.

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38

Millichap, J. Gordon. "Nonconvulsive Seizures in Critically Ill Children". Pediatric Neurology Briefs 21, n. 1 (1 gennaio 2007): 4. http://dx.doi.org/10.15844/pedneurbriefs-21-1-6.

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39

Kurz, Jonathan E., e Mark S. Wainwright. "Continuous EEG in Critically Ill Children". Pediatric Neurology Briefs 29, n. 3 (29 marzo 2015): 20. http://dx.doi.org/10.15844/pedneurbriefs-29-3-3.

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40

Nakagawa, S., e D. Bohn. "Respiratory support of critically ill children". Clinical Intensive Care 12, n. 1 (febbraio 2001): 1–9. http://dx.doi.org/10.3109/tcic.12.1.1.9.

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41

Garcia, Pedro Celiny Ramos, e Jefferson P. Piva. "New treatments for critically ill children". Jornal de Pediatria 79, n. 8 (15 novembre 2003): 125–2635. http://dx.doi.org/10.2223/jped.1088.

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42

Leow, Esther Huimin, Shui Yen Soh, Ah Moy Tan, Yee Hui Mok, Mei Yoke Chan e Jan Hau Lee. "Critically Ill Children With Hemophagocytic Lymphohistiocytosis". Journal of Pediatric Hematology/Oncology 39, n. 6 (agosto 2017): e303-e306. http://dx.doi.org/10.1097/mph.0000000000000916.

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43

Mehta, Nilesh M. "Parenteral Nutrition in Critically Ill Children". New England Journal of Medicine 374, n. 12 (24 marzo 2016): 1190–92. http://dx.doi.org/10.1056/nejme1601140.

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44

Thomas, David, e Robert Henning. "Emergency transport of critically ill children". Medical Journal of Australia 157, n. 1 (luglio 1992): 66–67. http://dx.doi.org/10.5694/j.1326-5377.1992.tb121619.x.

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45

Hendrix, Will. "Dialysis Therapies in Critically Ill Children". AACN Advanced Critical Care 3, n. 3 (1 agosto 1992): 605–13. http://dx.doi.org/10.4037/15597768-1992-3007.

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Technologic advances provide renal replacement therapies to critically ill pediatric patients. Having multiplied rapidly, the options for intervention and treatment of acute renal failure in infants and small children are numerous. Thus, the need for the dialysis nurse and the critical care nurse to maintain, expand, and develop a new baseline of knowledge is a constant challenge. This article explores the management and treatment options for acute renal failure in infants and children
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46

Williams, Lori. "Delirium Assessment in Critically Ill Children". AACN Advanced Critical Care 28, n. 1 (15 marzo 2017): 23–26. http://dx.doi.org/10.4037/aacnacc2017473.

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47

AMICO, JUDY, e RUTH DAVIDHIZAR. "Supporting families of critically ill children". Journal of Clinical Nursing 3, n. 4 (luglio 1994): 213–18. http://dx.doi.org/10.1111/j.1365-2702.1994.tb00391.x.

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48

Martinez, Enid E., Katherine Douglas, Samuel Nurko e Nilesh M. Mehta. "Gastric Dysmotility in Critically Ill Children". Pediatric Critical Care Medicine 16, n. 9 (novembre 2015): 828–36. http://dx.doi.org/10.1097/pcc.0000000000000493.

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Rao, Suchitra, Kevin Messacar, Michelle R. Torok, Anne-Marie Rick, Jeffrey Holzberg, Aaron Montano, Dayanand Bagdure et al. "Enterovirus D68 in Critically Ill Children". Pediatric Critical Care Medicine 17, n. 11 (novembre 2016): 1023–31. http://dx.doi.org/10.1097/pcc.0000000000000922.

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Choong, Karen. "Early Mobilization in Critically Ill Children". Pediatric Critical Care Medicine 17, n. 12 (dicembre 2016): 1194–95. http://dx.doi.org/10.1097/pcc.0000000000000992.

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