Tesi sul tema "Chromatography modelling and simulation"
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Jadhav, Sanket H. "Modelling and Simulation of Chromatographic Processes for Whey Proteins". Thesis, Curtin University, 2019. http://hdl.handle.net/20.500.11937/76482.
Irankunda, Rachel. "Nickel Chelating Peptides & Chromatography : From Peptides Separation Simulation up to their Antioxidant Activities - related Applications". Electronic Thesis or Diss., Université de Lorraine, 2023. http://www.theses.fr/2023LORR0213.
Metal-Chelating Peptides (MCPs), from protein hydrolysates, present various applications in nutrition, pharmacy, cosmetic etc. Yet, the empirical approach generally used to discover bioactive peptides from hydrolysates is time consuming and expensive due to many steps of fractionation, separation and biological activities evaluation. Thus, this PhD aimed to develop a novel approach for MCPs separation prediction using chromatography modelling and simulation based on the analogy between Immobilized Metal ion Affinity Chromatography (IMAC) and Surface Plasmon Resonance (SPR). For the first time, the SPR-IMAC analogy was experimentally investigated on 22 peptides and 70% of them validated this analogy, since peptides well retained in IMAC were also endowed with a good affinity for Ni2+ in SPR. In the second time, peptides with high affinity for Ni2+ (i.e low dissociation constant KD in SPR and a high retention time in IMAC) were used to study the modelling and simulation of peptide concentration profiles at the column outlet in IMAC. Since knowledge of adsorption isotherms was required to perform simulation, it was necessary to develop a methodology for predicting Langmuir isotherm parameters in IMAC from SPR data. The validity of simulation was evaluated by comparing experimental and simulated retention times that should be close for reliable prediction. Therefore, several approaches were evaluated to determine Langmuir sorption parameters, the most interesting one introduces a correction factor on the maximum adsorption capacity qmax alone, assuming that the affinity of peptides for immobilized Ni2+ did not change depending on the technology used (SPR vs. IMAC), thus affinity constant KA was not modified. Meanwhile, industrial application of MCPs and hydrolysates were studied. First, pea protein hydrolysates were produced by either Alcalase® followed by Flavourzyme® (Alc+Flav≤1kDa) or Protamex® followed by Flavourzyme® (Prot+Flav≤1kDa). SwitchSENSE® technology evidences the presence of Ni2+ chelating peptides and antioxidants tests showed that Prot+Flav≤1kDa has higher radical scavenging and reducing power, related to its higher degree of hydrolysis and small-size peptides quantity. Secondly, pea hydrolysates and MCPs were investigated for their ability to inhibit the lipid oxidation in emulsions. They slowed down lipid oxidation through chelation of prooxidant (metals such as Fe2+) reducing primary and secondary oxidation products responsible of deterioration of lipid containing products. Thus, pea hydrolysates and MCPs could be used as antioxidants in food and cosmetic products, as alternative to chemicals such as EDTA, BHT and TBHQ
El-Sayed, Mayyada. "Selective cation-exchange adsorption of the two major whey proteins". Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/225131.
Kapadi, Ajith Nayak. "Size Exclusion PEGylation Reaction Chromatography Modelling". The University of Waikato, 2006. http://hdl.handle.net/10289/2504.
Andersson, David. "Simulation Testbed for Liquid Chromatography". Thesis, Umeå universitet, Institutionen för fysik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-185024.
Ziebell, Angela Louise. "Modelling lignin depolymerisation using size exclusion chromatography". Swinburne Research Bank, 2008. http://hdl.handle.net/1959.3/35984.
Presented for full assessment for the degree of Doctor of Philosophy, Faculty of Life and Social Sciences, Swinburne University of Technology - 2008. Typescript. Bibliography: p. 222-246.
UMEMURA, TOMONARI, RYO KOMIYAMA e KAZUHIRO YAMAMOTO. "NUMERICAL SIMULATION ON FLOW IN COLUMN CHROMATOGRAPHY". World Scientific Publishing, 2013. http://hdl.handle.net/2237/20053.
Kurdi, Omar. "Crowd modelling and simulation". Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/18669/.
Ipsen, Andreas. "Probabilistic modelling of liquid chromatography time-of-flight mass spectrometry". Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/6903.
Scholtzova, Angela. "Scale up and modelling of HPLC". Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368109.
Shapiro, Janet. "Simulation modelling of spatial problems". Thesis, London Metropolitan University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294985.
Abdollahi, Mehrzad. "Vehicle ride modelling and simulation". Thesis, University of Birmingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633064.
Gove, Darryl James. "Simulation modelling of infectious diseases". Thesis, University of Southampton, 1997. https://eprints.soton.ac.uk/414488/.
Aronsson, Anders, e Martin Andersson. "Modelling and Simulation of Debt Portfolios". Thesis, Uppsala University, Department of Mathematics, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-122073.
Ezeanochie, Tochukwu Chinedu. "Modelling and Simulation of Filopodial Protrusion". Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32781.
Tam, Jimmy Chi-Ming. "An expert system for simulation modelling". Thesis, University of Ottawa (Canada), 1988. http://hdl.handle.net/10393/5097.
Bose, Sonia Manjusri. "Computer simulation modelling of polymer ageing". Thesis, University of Surrey, 2002. http://epubs.surrey.ac.uk/843495/.
Åkerström, Paul. "Modelling and simulation of hot stamping /". Luleå : Luleå tekniska universitet/Tillämpad fysik, maskin- och materialteknik/Hållfasthetslära, 2006. http://epubl.ltu.se/1402-1544/2006/30/LTU-DT-0630-SE.pdf.
Kalhori, Vahid. "Modelling and simulation of mechanical cutting". Doctoral thesis, Luleå, 2001. http://epubl.luth.se/1402-1544/2001/28/index.html.
Artuğ, Gamze. "Modelling and simulation of nanofiltration membranes". Göttingen Cuvillier, 2007. http://d-nb.info/986774685/04.
ANNA, RICARDO E. SILVA DE SANT. "ROTOR ACCIDENT ANALYSIS: MODELLING AND SIMULATION". PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2007. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=11885@1.
A problem related with an air compressor gave birth to the MSc Thesis. Problems related with rotative machines are usual in the industrial field. Difficulties come from the data gathering in order to analyze, and propose a theory of failure in order to explain and avoid the recurrence of such problem. Modelling a rotor with a Timoshenko beam element and the discretization by finite element method permit the dynamical analysis and the modal analysis of the rotor considering its interaction with the radial and thrust bearings (assuming stiffness and rigidity). The work is divided in seven chapters: chapter one introduces the work and gives the overview of it; chapter two describes the industrial problem; chapter three is a brief explanation of bearing types and the fundamental principle of lubrication; chapter four introduces vibration theory and modal analysis; chapter five introduces the finite element method; chapter six is the simulation of the problem, using tailor-made MATLABr programs to reconstruct the problem and to compare the test field results with the here mentioned formulation; chapter seven discusses the results and proposes future works. Appendix shows the kinetic theory and the beam deformation model used in the program and the Laval simple rotor as a limited description of the dynamic of a rotor with distributed mass, rigidity and stiffness. The aim of this work is to help understand and avoid the recurrence of the failure described and to easy the understanding of modal analysis for new engineers and technicians which will deal with rotor dynamics.
Barakat, Mamdouh Taysir. "Semantic modelling for discrete event simulation". Thesis, London School of Economics and Political Science (University of London), 1992. http://etheses.lse.ac.uk/2823/.
Poushpas, Saman. "Wind farm simulation modelling and control". Thesis, University of Strathclyde, 2016. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=27911.
Gärtner, Christian. "Organic laser diodes modelling and simulation". Karlsruhe Univ.-Verl. Karlsruhe, 2008. http://d-nb.info/993660703/04.
Hultberg, Ida. "Modelling and Simulation of Unknown Factors in Simulation Based Acquisition". Thesis, University of Skövde, Department of Computer Science, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-715.
When a new product should be acquired, a model over its functionality is made. A quite new idea in the military area is to use simulations to find out what and how much to acquire. Since the product never has been on the market before it is hard to know how factors in the surroundings, like weather and other active objects, will affect it. Therefore these unknown factors that appear during the creation or acquiring of a new product need to be taken into consideration.
A literature study is performed about how modelling of simulations can be done, and how unknown factors can be considered when modelling a simulation. The study goes into if unknown factors are taken into consideration when modelling in the Process component in Simulation Based Acquisition (SBA). The result of this study shows that SBA facilitates in the process of finding and reducing unknown factors.
Cherif, Redha. "Software Process Simulation Modelling : A Multi Agent-Based Simulation Approach". Thesis, Blekinge Tekniska Högskola, Avdelningen för programvarusystem, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-5787.
Tomlinson, S. P. "The hydraulic automatic simulation package (HASP) : Modelling and simulation aspects". Thesis, University of Bath, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375337.
Tang, A. "A novel USD-modelling tool for chromatography design : specification of resin properties". Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1352728/.
Bielow, Chris [Verfasser]. "Quantification and simulation of liquid chromatography-mass spectrometry data / Chris Bielow". Berlin : Freie Universität Berlin, 2012. http://d-nb.info/1030382883/34.
Teepakorn, Chalore. "Numerical simulation and experimental study of membrane chromatography for biomolecule separation". Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10299/document.
Membrane chromatography (MC) is an alternative to traditional resin packed columns chromatography. The solute mass transport in the membrane occurs in convective through-pores rather than in stagnant fluid inside the pores of the resins particles, which is limited by the slow diffusive transport. MC offers the main advantage of reducing diffusion phenomena, shorter residence time and lowered pressures drops, and thus, facilitates rapid purification of large quantities of molecules. A wide range of chromatographic membranes involving different molecules retention mechanisms (ion exchange, affinity, etc...) is now commercialized. Despite their success, the influence of the geometry of the membrane chromatography devices remains relatively unexplored from a theoretical point of view. This doctoral thesis is aimed to clarify some ambiguous points related to this technique
Bennett, Donald John. "Semiconductor process modelling". Thesis, University of the West of Scotland, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259677.
Ahmed, Rizwan. "A rapid simulation modelling process for novice software process simulation modellers". Thesis, University of Hertfordshire, 2005. http://hdl.handle.net/2299/14298.
Thewalim, Yasar. "Retention time predictions in Gas Chromatography". Doctoral thesis, Stockholm University, Department of Analytical Chemistry, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-55088.
At the time of the doctoral defense, the following paper was unpublished and had a status as follows: Paper 4: Submitted.
Oezkan, Oezguer. "Operational modelling practical manufacturing systems". Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323768.
Albertyn, Martin. "Generic simulation modelling of stochastic continuous systems". Thesis, Pretoria : [s.n.], 2004. http://upetd.up.ac.za/thesis/available/etd-05242005-112442.
Ulriksson, Jenny. "Consistency management in collaborative modelling and simulation". Licentiate thesis, KTH, Microelectronics and Information Technology, IMIT, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-571.
The aim of this thesis is to exploit the technological capabilities of computer supported collaborative work (CSCW) in the field of collaborative Modelling and Simulation (M&S). The thesis focuses on addressing two main problems: (i) providing flexible means of consistency management in collaborative M&S, and (ii) the ability of providing platform and application independent services for collaborative M&S.
In this work, some CSCW technologies and how some of the concepts can be incorporated in a distributed collaborative M&S environment, have been studied. An environment for component based simulation development and visualization, which provides support for collaborative M&S, has been designed. Some consistency policies that can be used in conjunction with distributed simulation and the High Level Architecture (HLA) have been investigated. Furthermore, the efficient utilization of HLA and XML in combination, as the foundation of a CSCW infrastructure has been proved. Two consistency policies were implemented utilizing HLA, a strict and an optimistic, in the distributed collaborative environment. Their performance was compared to the performance of a totally relaxed policy, in various collaboration situations.
Klang, Henrik, e Andreas Lindholm. "Modelling and simulation of a gas turbine". Thesis, Linköping University, Department of Science and Technology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2893.
In this thesis, a gas turbine simulator for the Siemens GT10C was developed and implemented.
It concerns everything from the theory behind the simulator; both the hard- ware and software involved, to how the actual simulator was built using these tools. The theory concerns itself with basic automatic control concepts, as well as basic turbine theory.
The simulator setup is being discussed concerning both technical and eco- nomic issues. A robust hardware solution is then selected, using the basic re- quirements, which the simulator then is built around.
The tools used are the Siemens SIMATIC automatic control system and the Siemens SIMIT real-time simulator using a SIMBA Pro PCI card to interface with the PLC:s in the SIMATIC system. Matlab are also used to a lesser extent to build the simulator behavior in SIMIT.
In the end, a fully featured simulator is presented that can be used for various purposes such as training operators, trying out new concepts and testing the automatic control system used to control the turbine.
Further development that could be done, by other engineers, in the future, is also discussed.
Lindström, Stefan. "Modelling and simulation of paper structure development". Doctoral thesis, Mittuniversitetet, Institutionen för naturvetenskap, teknik och matematik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-7003.
Uzir, Mohamad Hekarl. "Dynamic modelling and simulation of biocatalytic reactions". Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1446784/.
Eldabi, Tillal. "Simulation modelling : problem understanding in healthcare management". Thesis, Brunel University, 2000. http://bura.brunel.ac.uk/handle/2438/5264.
Lohy, Das Jesmin Permala. "Modelling and Simulation to Improve Antimalarial Therapy". Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-330113.
Gue, Chang Shin. "Submarine landslide flows simulation through centrifuge modelling". Thesis, University of Cambridge, 2012. https://www.repository.cam.ac.uk/handle/1810/243401.
O'Donovan, Brendan Donal. "Modelling and simulation of engineering design processes". Thesis, University of Cambridge, 2004. https://www.repository.cam.ac.uk/handle/1810/251938.
Kolachina, Srinivasa Kranthi Kiran, e Nishu Reddy. "Modelling and Simulation of a Resonant Converter". Thesis, Blekinge Tekniska Högskola, Institutionen för tillämpad signalbehandling, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3374.
+917893357437
Yaacob, Zulkefli. "Modelling and simulation of transient gas flow". Thesis, University of Salford, 1996. http://usir.salford.ac.uk/26975/.
El-Mounayri, Hazim A. "Generic solid modelling based machining process simulation". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ30083.pdf.
Pantea, Radu Catalin. "Wood cutting system, modelling and process simulation". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0020/MQ47226.pdf.
Nilsson, Annika. "Modelling and simulation of metal working processes /". Luleå, 2000. http://epubl.luth.se/1402-1544/2000/41/index.html.
Chaleeraktrakoon, Chavalit. "Stochastic modelling and simulation of streamflow processes". Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28704.
Wu, Hongjin. "Modelling and simulation of electric mining shovels". Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28964.