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Autore: Grafiati

Pubblicato: 25 luglio 2024

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1

Park, Min Su. "The Qing Occupation of Shanhai Pass and Beijing in 1644". CHUNGGUKSA YONGU (The Journal of Chinese Historical Researches) 110 (31 ottobre 2017): 103–45. http://dx.doi.org/10.24161/chr.110.103.

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2

Ho, Michelle, Oscar Florez-Vargas, Maxwell Hogshead, Brenen Papenberg, Chia Han Lee, Chi Zhang, Kaitlin Forsythe, Wusheng Yan, Raj Chari e Ludmila Prokunina-Olsson. "Abstract 1644: Exploring the role of a TERT intronic tandem repeat in regulating cell proliferative responses to environmental factors and cancer risk". Cancer Research 84, n. 6_Supplement (22 marzo 2024): 1644. http://dx.doi.org/10.1158/1538-7445.am2024-1644.

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Abstract The chr 5p15.33 genomic locus encoding telomerase reverse transcriptase (TERT) is structurally complex, with several highly polymorphic intronic variable number tandem repeats (VNTRs). A germline VNTR located in TERT intron 6 (VNTR6-1, 38 bp repeat unit) has previously been associated with TERT alternative splicing but its potential role in regulating cellular functions and disease risk is unclear. To functionally characterize VNTR6-1, we deleted this region (1-2 kb) using CRISPR/Cas9 in UMUC3 (bladder cancer cell line). Cell count growth tracking of parental and VNTR6-1 knockout (VNTR6-1 KO) cells via automated live-cell monitoring revealed different relative growth rates under serum starvation vs. normal conditions, suggesting that VNTR6-1 might be sensitive to growth factors present in culture media. Evaluation of growth in media with full vs. charcoal-stripped (CS) serum, showed significant differences, with higher cell counts in parental vs. VNTR6-1 KO in CS-serum (P=4.1e-3), parental vs. parental in full (P=1.57e-4) or CS-serum (P=4.76e-2), but not in parental vs. VNTR6-1 KO in full serum (P=0.378). After 5-6 days of growth, cells in CS-serum also rapidly began outgrowing cells in full serum. We observed that VNTR6-1 KO dampened the outgrowth response in cells lacking growth factors in CS-serum. Proliferation-specific growth assays tracking the dilution of an incorporated dye in cells by flow cytometry further showed that VNTR6-1 KO leads to more pronounced proliferation differences due to the presence or absence of serum-supplied factors. Overall, cell growth patterns appear to be sensitive to serum in interaction with VNTR6-1, suggesting a potential VNTR6-1-dependent response to extracellular signaling. In human populations, we have identified two VNTR6-1 groups: Short (24-27 copies) and Long (40.5-66.5 copies). In the PLCO dataset (n=100,445 cancer cases and controls), logistic regression showed that VNTR6-1-Long group was associated with a decreased risk in male-prevalent cancers such as bladder and prostate, but an increased risk in female-prevalent cancers such as breast, endometrial and ovarian. These results support a link between the TERT region, and potentially VNTR6-1, with hormone signaling and cancer risk. Motif analysis within VNTR6-1 predicted binding sites for several transcription factors, including those associated with development and cell growth. Together, these results suggest that VNTR6-1 may be involved in regulating cell growth, potentially by facilitating responses to extracellular signaling pathways. Additionally, given the location of VNTR6-1 within a multi-cancer GWAS region, our findings provide functional context for the role of this polymorphic repeat in differential risk and outcomes in certain cancers. Citation Format: Michelle Ho, Oscar Florez-Vargas, Maxwell Hogshead, Brenen Papenberg, Chia Han Lee, Chi Zhang, Kaitlin Forsythe, Wusheng Yan, Raj Chari, Ludmila Prokunina-Olsson. Exploring the role of a TERT intronic tandem repeat in regulating cell proliferative responses to environmental factors and cancer risk [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 1644.

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3

Lowerre, Kathryn. "Music in the English Courtly Masque, 1604-1640 (review)". Comparative Drama 34, n. 1 (2000): 124–26. http://dx.doi.org/10.1353/cdr.2000.0034.

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4

Cook, Peter. "Onontio Gives Birth: How the French in Canada Became Fathers to Their Indigenous Allies, 1645–73". Canadian Historical Review 96, n. 2 (giugno 2015): 165–93. http://dx.doi.org/10.3138/chr.2917.

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5

Dijker, Thomas, Piet H. L. Bovy e Raymond G. M. M. Vermijs. "Car-Following Under Congested Conditions: Empirical Findings". Transportation Research Record: Journal of the Transportation Research Board 1644, n. 1 (gennaio 1998): 20–28. http://dx.doi.org/10.3141/1644-03.

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In traffic flow analysis several regimes are distinguished, such as congested and noncongested flow conditions. Indications exist that driving behavior differs by regime and that it may change discontinuously between regimes. In contrast most traffic flow models used today basically assume the same car-following behavior irrespective of the traffic flow regime. It is hypothesized that, because of this deficiency, these models do not always perform satisfactorily. To clarify this issue, differences in car-following between congested and noncongested flow are analyzed with data from two sites on Dutch freeways. It is shown that, at the same speeds, passenger car drivers follow with smaller headways in noncongested than in congested flow. Car-following of truck drivers does not show differences between regimes. Microscopic distance gap-speed models are established for several road-user classes, valid for each of the two flow regimes. To show the improvements resulting from these new microscopic relationships, the latter are implemented in a microscopic simulation model with which macroscopic patterns in traffic flow are modeled. The macroscopic findings produced with the regime-specific car-following rules show a considerable improvement in modeling performance.

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6

Aycin, M. F., e R. F. Benekohal. "Linear Acceleration Car-Following Model Development and Validation". Transportation Research Record: Journal of the Transportation Research Board 1644, n. 1 (gennaio 1998): 10–19. http://dx.doi.org/10.3141/1644-02.

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A linear acceleration car-following model has been developed for realistic simulation of traffic flow in intelligent transportation systems (ITS) applications. The new model provides continuous acceleration profiles instead of the stepwise profiles that are currently used. The brake reaction times of the drivers are simulated effectively and are independent of the simulation time steps. Chain-reaction times of the drivers are also simulated and perception thresholds are incorporated in the model. The preferred time headways are utilized to determine the simulated drivers’ separation during car-following. The features of the model and the realistic vehicle simulation in car-following and in stop-and-go conditions make this model suitable to ITS, especially to autonomous intelligent cruise-control systems. The car-following algorithm is validated at microscopic and macroscopic levels by using field data. Simulated versus field trajectories and statistical tests show very strong agreement between simulation results and field data.

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7

Buoye, Thomas. "Bare Sticks and Naked Pity : Rhetoric and Representation in Qing Dynasty (1644-1911). Capital Case Records". Crime, Histoire & Sociétés 18, n. 2 (1 ottobre 2014): 27–47. http://dx.doi.org/10.4000/chs.1485.

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8

Triboulet, R. "Corneille et l'aspiration au martyre". Revue d'histoire littéraire de la France o 85, n. 5 (1 maggio 1985): 771–84. http://dx.doi.org/10.3917/rhlf.g1985.85n5.0771.

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Résumé Corneille fait représenter en 1643 Polyeucte, martyr, tragédie chrétienne , dont le succès suscite plusieurs tragédies analogues, et en 1645 Théodore, vierge et martyre, tragédie chrétienne , qui subit « une telle disgrâce que l'on renvoie ces sortes de sujets dans les collèges ». Polyeucte n'est pas un témoignage de la dévotion de son temps, sinon par le choix du martyre, imitation suprême de Jésus- Christ Car ces martyrs chrétiens, précisément, se réfèrent aussi peu que possible au Crucifié, mais à leurs vertus, à leur gloire, au renoncement, aux cieux que leur ouvre un Dieu maître de l'Univers. Aussi ne faut-il pas s'étonner que, si Polyeucte est contesté, ce soit par les dévots, notamment ceux de Normandie évoqués dans cet article. Mais Corneille, merveilleux ouvrier de théâtre, pouvait-il christianiser davantage le type de héros qui, du Cid à Cinna, en passant par Horace, lui assurait un public enthousiaste ? N'avait-il pas eu en même temps scrupule de mettre sur la scène l'amour mystique du Christ ?

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9

Stolecka-Makowska, Agata, e Robert Wolny. "The Idea of Car Sharing as a Manifestation of Sustainable Consumption". Problemy Zarzadzania 16, n. 3 (75) (17 luglio 2018): 182–96. http://dx.doi.org/10.7172/1644-9584.75.11.

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10

Husak, Y. V., O. A. Holichenko, V. V. Zakatov e A. V. Shtemenko. "Interaction of trans-tetrachlorodi-m-carboxylates of dirhenium(III) with dipeptides of the glycyl series". Voprosy Khimii i Khimicheskoi Tekhnologii, n. 3 (giugno 2022): 21–25. http://dx.doi.org/10.32434/0321-4095-2022-142-3-21-25.

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The paper reports the methods for the synthesis of new cluster compounds of trans-tetrachlorodi--carboxylates of dirhenium(III) with dipeptides of the glycyl series. The compositions and the structures were determined by electron absorption and IR spectroscopies as well as by elemental analysis for the following newly synthesized compounds: trans-[Re2(H3N+–CH2–СO–NH–CH(COO)–CH2–CH(CH3)–CH3)2Cl42СН3CN]Cl2 (І) and trans-[Re2(H3N+–CH2–СO–NH–CH(COO)–CH2–C6H5)2Cl42СН3CN]Cl2 (ІІ). Analysis of the electronic absorption spectra of the solutions of the synthesized substances showed the presence of a doublet pattern (12500 and 16129 сm–1), which corresponds to the *-electronic transition of the Re–Re quadruple bond characteristic of solutions of trans-tetrachlorodi--carboxylates of dirhenium(III). The appearance of oscillations at 1485 сm–1 for І and 1486 сm–1 for ІІ, characteristic of the s(CO) of the coordinated carboxylate group, was detected on the IR spectra, which indicates the bridging coordination of this group to the Re26+ binuclear fragment. The protonation of the amino group is indicated by the appearance of a wide band of valence oscillations (NH3+) in the range of 3400–3350 сm–1 and deformation oscillations (NH3+) at 1557 сm–1 and 1614 сm–1 for I and II, respectively. The stability of the obtained complex compounds in aqueous solutions was determined. It was shown that the hydrolysis of the synthesized substances takes place in 4–5 days, which is accompanied by a decrease in the pH of the reaction solution.

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11

Finkelstein, Richard. "Anticourt Drama in England, 1603-1642 by Albert H. Tricomi". Comparative Drama 24, n. 1 (1990): 88–91. http://dx.doi.org/10.1353/cdr.1990.0021.

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12

Brennan, Michael G. "Textual Patronage in English Drama, 1570-1640 (review)". Comparative Drama 40, n. 3 (2006): 377–80. http://dx.doi.org/10.1353/cdr.2006.0032.

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13

Petrov, A. P., e S. N. Bannikov. "Active Shutters of the Internal Combustion Engine Cooling System of a Passenger Car". Proceedings of Higher Educational Institutions. Маchine Building, n. 4(709) (aprile 2019): 44–51. http://dx.doi.org/10.18698/0536-1044-2019-4-41-51.

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The practice of using active shutters in the modern automotive industry is analyzed in this work, and the high efficiency of such systems is emphasized. It is also noted that by using active shutters the aerodynamic drag of the car can be reduced by 6–10 %. The reduction in the engine’s warm-up time provides faster heating of the car interior. All this helps to save fuel and reduce emissions of harmful substances into the atmosphere. The possibility of utilizing the radiator’s active shutters with two autonomously controlled sections is considered. CFD numerical modelling is used to conduct the research, and the potential of the proposed active shutters design is determined. The research has shown that besides the high efficiency, the proposed shutters system has a simpler design and reliability associated with several factors. Due to the vertical arrangement of the slats, the shutters do not reduce the efficiency of the engine’s cooling system and the air conditioning system in the passenger compartment. Unlike in the existing designs, in the proposed system the cooling air supply is regulated by separate opening or closing of two independent sections.

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Ersoy, Yusuf, e Adem Aktaş. "Health System Efficiency of OECD Countries with Data Envelopment Analysis". Problemy Zarządzania - Management Issues 2022, n. 4(98) (20 dicembre 2022): 90–109. http://dx.doi.org/10.7172/1644-9584.98.4.

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Purpose: This study is aimed at measuring the efficiency of 37 OECD countries for 2020 using the Data Envelopment Analysis (DEA) method. Besides, it is aimed at ranking the efficient decision making units by using the super-efficiency DEA model. Design/methodology/approach: In the study, analyses were carried out with input-oriented Charnes, Cooper and Rhodes (CCR), input-oriented Banker, Charnes and Cooper (BCC) models and super-efficiency models of these models by using 4 inputs and 3 outputs. Findings: As a result of the analysis, 14 countries in the CCR model and 20 countries in the BCC model were efficient. According to the results of the super-efficiency models, the efficient countries were ranked. Research limitations/implications: The limitations of the study are the analyses are based on input-oriented DEA models and the research was conducted in OECD countries. Originality/value: Performance evaluation of health systems has gained importance in recent years. Many countries are making efforts to improve their health systems. Due to epidemics such as COVID-19, OECD countries, like many countries around the world, have increased the share of health expenditures in GDP. Because of this situation, the evaluation of the performance of OECD countries in the field of health has emerged as a very important research topic.

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Jensen, Ejner J. "The Profession of Player in Shakespeare’s Time, 1590–1642 by Gerald Eades Bentley". Comparative Drama 19, n. 4 (1985): 363–65. http://dx.doi.org/10.1353/cdr.1985.0039.

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16

Friedman, Michael D. "A Dictionary of Stage Directions in English Drama, 1580-1642 (review)". Comparative Drama 35, n. 2 (2001): 225–28. http://dx.doi.org/10.1353/cdr.2001.0036.

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17

Zhao, Xiaobin B., Sabyasachi Biswas, Andrew Mone, Jeffrey Ledbetter, Martha Hayden Ledbetter, Laura Grosmaire, Erik Espling et al. "Novel Anti-CD37 Small Modular Immunopharmaceutical (SMIP) Induces B-Cell-Specific, Caspase-Independent Apoptosis in Human CLL Cells." Blood 104, n. 11 (16 novembre 2004): 2515. http://dx.doi.org/10.1182/blood.v104.11.2515.2515.

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Abstract Tru 16.4 is a single chain protein with a modified CD37 binding Fv domain linked to a modified human IgG1 hinge, CH2 and CH3 domains. It is a member of a novel composition class called small modular immunopharmaceuticals (SMIP) construct. CD37 is a stable marker for B-cell chronic lymphocytic leukemia (BCLL) and non-Hodgkins lymphoma (NHL). Although radiolabeled murine anti-CD37 antibody MB-1 has been evaluated in NHL patients and shown to be able to target tumors, efficacy was not established. There has been no evaluation of an unconjugated anti-CD37 antibody in human clinical trials. Here we report that Tru 16.4, binds to CD37 on primary CLL cells surface, and induces caspase-independent apoptosis that is further enhanced by a secondary crosslinking with goat anti-human antibody. The percentage of dead cell population over control based upon Annexin V/PI staining of 12 BCLL patient samples (28.3%, SD 15.4%) is significantly greater than that of isotype control, trastuzumab (3.4%, SD 7.6%). The expression of CD37 on T cells is low, and the exposure of Tru 16.4 under the same conditions does not demonstrate significant binding or induce noticeable apoptosis on normal T cells at 24 hours (0.47%, SD 0.99%). This provides a selective advantage for BCLL antibody therapy. Results from a comparison study utilizing 6 additional patient samples demonstrated that Tru 16.4 induced apoptosis (31.8%, SD 12.2%) is significantly higher than that of the anti-CD20 antibody, rituximab (21.8%, SD 5.25%) and similar to that observed with the anti-CD52 antibody, alemtuzumab (36.6%, SD 19.5%). The cell death induced by Tru 16.4 is dependent upon dose and duration of treatment, indicating 5μg/mL as a saturation concentration and 24 hours as the optimal time for maximal in vitro apoptosis. The degree of CLL cell death was found to be directly proportionate to cell surface membrane expression of CD37, based on nonparametric Spearman rank correlation analysis of the mean fluoresecnce intensity (MFI) after PE-labelled anti-CD37 antibody immunostaining and percentages of Annexin V/PI positive cells, with a correlation factor rs = 0.80 ( P < 0.01). Ongoing studies suggest Tru 16.4 induces intracellular signaling following CD37 antigen ligation and current efforts are focused on identifying the specific death pathways mediated by this treatment. Overall, these findings indicate that Tru 16.4 mediates B-cell specific apoptosis through a novel caspase independent mechanism and supports effort for further clinical investigation in CLL.

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Wang, Yuhao, e Panos D. Prevedouros. "Comparison of INTEGRATION, TSIS/CORSIM, and WATSim in Replicating Volumes and Speeds on Three Small Networks". Transportation Research Record: Journal of the Transportation Research Board 1644, n. 1 (gennaio 1998): 80–92. http://dx.doi.org/10.3141/1644-09.

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INTEGRATION, TSIS/CORSIM, and WATSim can simulate traffic operations on mixed arterial and freeway networks. Comparisons are presented here using three small networks in Honolulu for which detailed, simultaneous, and contemporaneous flow conditions are known. The models produced reasonable and comparable results on most network links. Of the three software programs, only INTEGRATION can simulate U-turns, but it also is least able to model complex signal operations. TSIS/CORSIM is best at replicating lane-changing behavior, but its percentile input for off-ramps is both inconvenient and inaccurate. WATSim needed the least calibration for producing good results, but its animation is inferior and its capacity-based car-following parameters are undesirable. The default parameters off all three software programs never offered satisfactory results.

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19

Apriani, Wiwin, e Nurhayati Nurhayati. "Metode Cluster Pautan Tunggal untuk Analisis Heterogenitas Demografi di Kabupaten Aceh Jaya". Asimetris: Jurnal Pendidikan Matematika dan Sains 4, n. 2 (31 ottobre 2023): 128–36. http://dx.doi.org/10.51179/asimetris.v4i2.2245.

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Berdasarkan data sensus penduduk tahun 2020 di Kabupaten Aceh Jaya dapat dilihat keheterogenan jumlah penduduk, tingkat Pendidikan, lapangan usaha, dan jenis perumahan dengan menggunakan analisis cluster pautan Tunggal. Dari hasil analisis di[eroleh keheterogenan populasi penduduk di Kabupaten Aceh Jaya paling besar yaitu di Kecamatan Panga dan Jaya dengan sebesar 157,23364%. Pada tingkat pendidikan keheterogenan terjadi pada kecamatan Panga dan Jaya sebesar 90,19637%. Sektor lapangan usaha keheterogenan terjadi pada Kecamatan Panga dan Jaya sebesar 91,453%. Analisis demografis menunjukkan bahwa untuk tingkat kelahiran, persentase CBR tertinggi berada di Kecamatan Sampoiniet dengan nilai 2,94%. dan terkecil 2,11% di Kecamatan Krueng Sabee. Pada tingkat ASFR persentase terbesar terdapat di Kabupaten Jaya dengan nilai 26,34% dan terkecil di Kecamatan Krueng Sabee dengan nilai 16,44%. Selanjutnya pada tingkat GFR persentase terbesar sebesar 18,23% di Kecamatan Setia Bakti dan terkecil sebesar 10,21% di Kecamatan Teunom sedangkan untuk tingkat kematian persentase CDR tertinggi sebesar 29,43% di Kecamatan Sampoiniet dan terkecil sebesar 21,07% di Krueng Sabee.

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Hassab, Hoda MA, Wafaa A. El-Neanaey, Ghada M. F. El-Deriny e Eman El-Mahy. "Recent Versus Conventional Iron Status Parameters for Diagnosis of Anemia in Juvenile Idiopathic Arthritis Patients". Blood 126, n. 23 (3 dicembre 2015): 3360. http://dx.doi.org/10.1182/blood.v126.23.3360.3360.

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Abstract Objective: Juvenile Idiopathic Arthritis (JIA) is commonly associated with different types of anemia. The diagnosis and treatment of IDA is a medical necessity; being a well-recognized cause of both short and long term morbidity plus being strongly related to poor disease outcome. In the presence of concomitant chronic illness or inflammation, the diagnosis of iron deficiency using the conventional laboratory parameters is a major medical challenge. Therefore, the utility of two recent iron status parameters; hepcidin-25 "active form of iron metabolism negative regulator" and reticulocyte hemoglobin content (CHr) "functional anemia indicator" was compared to that of two conventional ones; transferrin saturation (TSAT) and red cell distribution width percentages (RDW%) in diagnosing iron deficiency anemia in patients with JIA. Methods: Blood samples were obtained from 43 JIA patients whose ages ranged from 3 to 16 years and 20 age and sex matched healthy children as control group. Three different types of anemia; iron deficiency anemia (IDA), anemia of chronic disease (ACD) and combined anemia (IDA/ACD) were identified within the studied patients using iron profile, ESR and C-reactive protein. Serum hepcidin-25 was assessed by ELISA technique; CHr, TSAT% and RDW% were all estimated using Siemens ADVIA 2120 analyzer in patients and the control group. Results: Anemia was identified in 22 (51.2%) patients. Serum hepcidin-25 and TSAT% were significantly lower in IDA than ACD & IDA/ACD patients (p= 0.032 and p=0.034 for hepcidin and p= 0.004 and p=0.012 for TSAT%). Significantly lower CHr and higher RDW% were found in IDA/ACD compared to ACD patients (p= 0.032 and p< 0.001, respectively). Serum hepcidin ≤ 3.8ng/mL and TSAT% ≤ 5.8% differentiated IDA from both ACD and IDA/ACD with 80 and 100% sensitivity and 88.24% specificity. CHr ≤24.4pg and RDW % > 16.4% showed 80 and 90% sensitivity and 100% specificity; distinguishing IDA/ACD from ACD. Conclusion: Serum hepcidin and CHr were not superior to TSAT% and RDW%; discriminating among different types of anemia in JIA patients. Table 1. Comparison between anemia subgroups according to CHr and serum hepcidin IDA(n=5) ACD(n=6) Combined anemia(n=7) Control(n=20) p CHr (pg) 23.61 ± 3.80a 27.36 ± 2.30b 23.37 ± 3.18a 30.54 ± 1.99 <0.001* Serum hepcidin (ng/ml) 3.60 (3.0-4.9)bc 5.10 (3.10 - 90.0) 7.15 (3.1-60.0) 5.0 (0.10-10.8) 0.121 Data was expressed as Mean ± SD. for normally distributed data and Median (Min. - Max.) for abnormaly distrbutied data a: Significant with control gorup b: Significant with combined anemia group c: Significant with ACD group Table 2. Comparison among anemia subgroups and control group according to RDW & TSAT% IDA(n=5) ACD(n=7) Combined anemia(n=10) Control(n=20) Test of sig. p RDW% Min. - Max. 17.30 - 19.90 13.10 - 16.40 15.60 - 22.0 12.40 - 15.80 F=45.032* <0.001* Mean ± SD. 18.42 ± 1.04 14.49 ± 1.30 18.46 ± 1.92 13.47 ± 0.86 Median 2.62 13.90 18.20 13.10 Sch p* p1<0.001* ,p2=0.362,p3<0.001* ,p4=1.000,p5<0.001* ,p6<0.001* TSAT % Min. - Max. 4.20 - 5.80 6.0 - 20.50 4.40 - 26.0 11.0 - 40.0 KW χ2 =* <0.001* Mean ± SD. 4.78 ± 0.64 10.73 ±4.82 13.82 ± 8.63 22.71 ± 8.32 Median 4.50 10.0 12.80 20.70 MW p1 0.001* 0.001* 0.016* MW p2 0.012* 0.660 MW p3 0.004* KW c2 : Chi square for Kruskal Wallis test F: F test (ANOVA) p1: p value for comparing between control and IDA p2: p value for comparing between control and ACD p3: p value for comparing between control and combined anemia p4: p value for comparing between combined anemia and IDA p5: p value for comparing between combined anemia and ACD p6: p value for comparing between ACD group and IDA group MW: Mann Whitney test Sch: Post Hoc Test (Scheffe) *: Statistically significant at p ≤ 0.05 Table 3. Agreement (sensitivity, specificity and accuracy) for serum hepcidin and TSAT% with IDA vs. ACD and combined anemia in JIA patients ACD and combined anemia IDA Sensitivity Specificity PPV NPV Accuracy Serum hepcidin (ng/ml) >3.8 15 1 80.0 88.24 66.67 93.75 86.36 <3.8 2 4 TSAT% >5.8 15 0 100.0 88.24 71.43 100.0 90.91 ≤5.8 2 5 Table 4. Agreement (sensitivity, specificity and accuracy) for CHr and RDW% with ACD vs. combined anemia in JIA patients ACD Combined anemia Sensitivity Specificity PPV NPV Accuracy CHr >24.4 7 2 80 100.0 100.0 77.78 88.24 ≤24.4 0 8 RDW % ≤16.4 7 1 90.0 100.0 100.0 87.50 94.12 >16.4 0 9 Disclosures No relevant conflicts of interest to declare.

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Egger, Carole. "La violence du mensonge historique : Himmelweg de Juan Mayorga, un chemin vers la vérité". Recherches, n. 19 (1 dicembre 2017): 99–112. http://dx.doi.org/10.4000/cher.1647.

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Leloup, Pieter. "The private security industry in Antwerp (1907-1934). A historical-criminological analysis of its modus operandi and growth". Crime, Histoire & Sociétés 19, n. 2 (1 novembre 2015): 119–47. http://dx.doi.org/10.4000/chs.1604.

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Champeyrache, Clotilde. "Jason Pine, The Art of Making Do in Naples". Crime, Histoire & Sociétés 19, n. 2 (1 novembre 2015): 156–58. http://dx.doi.org/10.4000/chs.1614.

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Derasse, Nicolas. "Françoise Briegel, Négocier la défense. Plaider pour les criminels au siècle des Lumières à Genève Paris, Presses de Sciences Po, 2013, 296 p., ISBN 9 782724 812721". Crime, Histoire & Sociétés, Vol. 20, n°1 (1 giugno 2016): 296. http://dx.doi.org/10.4000/chs.1646.

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Campion, Jonas. "Chris Williams, Police Control Systems in Britain 1775-1975. From parish constable to national computer, Manches". Crime, Histoire & Sociétés, Vol. 20, n°1 (1 giugno 2016): 242. http://dx.doi.org/10.4000/chs.1648.

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26

Nesmith, Chris. "Imaginary Citizens: Child Readers and the Limits of American Independence, 1640–1868 by Courtney Weikle-Mills". Children's Literature Association Quarterly 38, n. 4 (2013): 489–92. http://dx.doi.org/10.1353/chq.2013.0059.

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27

Hirschfeld, Heather. "Staging Authority in Caroline England: Prerogative, Law and Order in Drama, 1625–1642 by Jessica Dyson". Comparative Drama 49, n. 2 (2015): 243–46. http://dx.doi.org/10.1353/cdr.2015.0015.

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28

Conti, Meredith A. "New World Drama: The Performative Commons in the Atlantic World, 1649–1849 by Elizabeth Maddock Dillon". Comparative Drama 49, n. 2 (2015): 236–39. http://dx.doi.org/10.1353/cdr.2015.0024.

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29

Coralynne Rapp, Martha. "Imaginary Citizens: Child Readers and the Limits of American Independence, 1640–1868 by Courtney Weikle-Mills". Children's Literature 42, n. 1 (2014): 275–79. http://dx.doi.org/10.1353/chl.2014.0000.

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30

Pezzuti, Lina, Margherita Lang, Serena Rossetti e Clara Michelotti. "CHC Model According to Weiss". Journal of Individual Differences 39, n. 1 (gennaio 2018): 53–59. http://dx.doi.org/10.1027/1614-0001/a000249.

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Abstract (sommario):

Abstract. The Italian version of the Wechsler Adult Intelligence Scale – Fourth Edition (WAIS-IV) – was standardized using a sample of 2,174 participants, aged between 16 and 90 years. The WAIS-IV consists of 10 core subtests and 5 supplemental subtests. While the 70–90 yr group is usually excluded from three of the five supplemental subtests (Letter-Number Sequencing, Figure Weights, and Cancellation), we administered all 15 subtests both to adults and elderly people. The aim of the present study was to investigate the factorial invariance of the Weiss and colleagues’ hierarchical five-factor CHC (Cattell-Horn-Carroll) model in Italian adults and elders. The overall results of this study generally support both the configural and factorial invariance of the WAIS-IV, and hence the five-factor CHC model of Weiss is equivalent in adults and elderly people. However, for the elderly sample we found higher loadings of WAIS-IV subtests on the second-order g factor.

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31

Minkwitz, Rolf, Raimund Bröchler e Hans Preut. "Tieftemperatur-Kristallstruktur der Einschlußverbindung {[N(CH3)4]+Cl]2-} · CH3CN · H2O / Low-Temperature Crystal Structure of the Inclusion Compound {[N(CH3)4]+Cl]2-} · CH3CN · H2O". Zeitschrift für Naturforschung B 51, n. 4 (1 aprile 1996): 599–601. http://dx.doi.org/10.1515/znb-1996-0426.

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Abstract The crystal structure of {[N(CH3)4+Cl]2}·CH3CN · H2O is reported. Crystalls are orthorhombic, space group Pnma, with a = 1622.9(15), b = 671.3(6), c = 1511.2(11) pm, V = 1646(2) 106 pm3 and Z = 4.

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32

Hoffmann, Dietrich. "The Holocene Marine Transgression in the Region of the North Frisian Islands". E&G Quaternary Science Journal 35, n. 1 (1 gennaio 1985): 61–70. http://dx.doi.org/10.3285/eg.35.1.10.

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Abstract. Um die unterschiedliche Entwicklung des Küstenholozäns im Bereich der Nordfriesischen Inseln darzustellen, wird die relativ gering mächtige — weniger als 10 m — Schichtenfolge von Sylt mit der teilweise über 20 m mächtigen bei Pellworm verglichen. Bei Sylt läßt sich das Küstenholozän in drei Sedimentdecken untergliedern, die durch eine Torflage oder humosen Klei und durch einen Humusdwog voneinander getrennt werden. Seit 2.000 Jahren lag die Marschoberfläche höher als das MThw. Die Größe der Marsch nahm seit dem Mittelalter als Folge ständiger Erosion ab. Im Gebiet um Pellworm ist eine Gliederung der vor Chr. Geb. abgelagerten Sedimente wegen des kleinräumigen Fazieswechsels nicht möglich. Als Folge erheblicher Setzungen während des ersten nachchristlichen Jahrtausends und der Kultivierungsarbeiten seit dem Mittelalter wurden die Marschoberflächen niedriger gelegt. In den Jahren 1362 und 1634 n. Chr. Geb. wurden sie von Sturmflutkatastrophen betroffen, große Teile ins Wattenmeer einbezogen und von den Siedlern verlassen. Die Gründe für diese Ereignisse sind teils auf die geologische Entwicklung, teils auf die Einwirkung des Menschen zurückzuführen. Der Ablauf der vor allem jüngeren Landschaftsgeschichte wurde in den verglichenen Gebieten in erheblichem Maße von lokalen Faktoren beeinflußt.

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33

Botello, Jesús. "Imperial Tapestries: Narrative Form and the Question of Spanish Habsburg Power, 1530–1647 by Julia L. Farmer". Cervantes: Bulletin of the Cervantes Society of America 38, n. 1 (2018): 221–27. http://dx.doi.org/10.1353/cer.2018.0011.

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34

MESJASZ-LECH, Agata. "Recycling of end-of-life vehicles - car manufacturer's view". Scientific Papers of Silesian University of Technology. Organization and Management Series 2017, n. 102 (2017): 225–38. http://dx.doi.org/10.29119/1641-3466.2017.102.19.

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35

Viba, Janis, Gundars Liberts e Vladimirs Gonca. "CAR ROLLOVER COLLISION WITH PIT CORNER". TRANSPORT 24, n. 1 (31 marzo 2009): 76–82. http://dx.doi.org/10.3846/1648-4142.2009.24.76-82.

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Abstract (sommario):

The paper presents a theory of body collision with pit corner. The theory can be successfully applied in approaching tasks coping with the orientation of details in technological processes and control systems, the motion of elements in mechanisms having a gap, collisions in motion of different sport objects, the analysis of car accidents etc. The applied theory deals with car motion after collision with a specific obstacle i.e. pit corner. The study is based on linear and angular momentum theorems and two restitution coefficients of normal impulse from both sides of the obstacle. The obtained results can be used for assessing road accidents in case of car collision with one or more obstacles. The object of contact may involve hitting a plane foundation, the ditch and edging of a highway or a rock in the field.

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36

Nykänen, H., S. Peura, P. Kankaala e R. I. Jones. "Recycling and fluxes of carbon gases in a stratified boreal lake following experimental carbon addition". Biogeosciences Discussions 11, n. 11 (28 novembre 2014): 16447–95. http://dx.doi.org/10.5194/bgd-11-16447-2014.

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Abstract. Partly anoxic stratified humic lakes are important sources of methane (CH4) and carbon dioxide (CO2) to the atmosphere. We followed the fate of CH4 and CO2 in a small boreal stratified lake, Alinen Mustajärvi, during 2007–2009. In 2008 and 2009 the lake received additions of dissolved organic carbon (DOC) with stable carbon isotope ratio (δ13C) around 16‰ higher than that of local allochthonous DOC. Carbon transformations in the water column were studied by measurements of δ13C of CH4 and of the dissolved inorganic carbon (DIC). Furthermore, CH4 and CO2 production, consumption and emissions were estimated. Methane oxidation was estimated by a diffusion gradient method. The amount, location and δ13C of CH4-derived biomass and CO2 in the water column were estimated from the CH4 oxidation pattern and from measured δ13C of CH4. Release of CH4 and CO2 to the atmosphere increased during the study. Methane production and almost total consumption of CH4 mostly in the anoxic water layers, was equivalent to the input from primary production (PP). δ13C of CH4 and DIC showed that hydrogenotrophic methanogenesis was the main source of CH4 to the water column, and methanogenic processes in general were the reasons for the 13C-enriched DIC at the lake bottom. CH4 and DIC became further 13C-enriched in the anoxic layer of the water column during the years of DOC addition. Even gradient diffusion measurements showed active CH4 oxidation in the anoxic portion of the water column; there was no clear 13C-enrichment of CH4 as generally used to estimate CH4 oxidation strength. Increase in δ13C-CH4 was clear between the metalimnion and epilimnion where the concentration of dissolved CH4 and the oxidation of CH4 were small. Thus, 13C-enrichment of CH4 does not reveal the main location of methanotrophy in a lake having simultaneous anaerobic and aerobic oxidation of CH4. Overall the results show that organic carbon is processed efficiently to CH4 and CO2 and recycled in the anoxic layer of stratified boreal lakes by CH4 oxidation. In spite of this, increased DOC input led to increased greenhouse gas release, mainly as CO2 but also as CH4. Due to the predominantly anaerobic CH4 oxidation, a relatively small amount of CH4-derived biomass was produced, while a large amount of CH4-derived CO2 was produced in the anoxic bottom zone of the lake.

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37

Spahni, R., R. Wania, L. Neef, M. van Weele, I. Pison, P. Bousquet, C. Frankenberg et al. "Constraining global methane emissions and uptake by ecosystems". Biogeosciences 8, n. 6 (23 giugno 2011): 1643–65. http://dx.doi.org/10.5194/bg-8-1643-2011.

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Abstract. Natural methane (CH4) emissions from wet ecosystems are an important part of today's global CH4 budget. Climate affects the exchange of CH4 between ecosystems and the atmosphere by influencing CH4 production, oxidation, and transport in the soil. The net CH4 exchange depends on ecosystem hydrology, soil and vegetation characteristics. Here, the LPJ-WHyMe global dynamical vegetation model is used to simulate global net CH4 emissions for different ecosystems: northern peatlands (45°–90° N), naturally inundated wetlands (60° S–45° N), rice agriculture and wet mineral soils. Mineral soils are a potential CH4 sink, but can also be a source with the direction of the net exchange depending on soil moisture content. The geographical and seasonal distributions are evaluated against multi-dimensional atmospheric inversions for 2003–2005, using two independent four-dimensional variational assimilation systems. The atmospheric inversions are constrained by the atmospheric CH4 observations of the SCIAMACHY satellite instrument and global surface networks. Compared to LPJ-WHyMe the inversions result in a~significant reduction in the emissions from northern peatlands and suggest that LPJ-WHyMe maximum annual emissions peak about one month late. The inversions do not put strong constraints on the division of sources between inundated wetlands and wet mineral soils in the tropics. Based on the inversion results we diagnose model parameters in LPJ-WHyMe and simulate the surface exchange of CH4 over the period 1990–2008. Over the whole period we infer an increase of global ecosystem CH4 emissions of +1.11 Tg CH4 yr−1, not considering potential additional changes in wetland extent. The increase in simulated CH4 emissions is attributed to enhanced soil respiration resulting from the observed rise in land temperature and in atmospheric carbon dioxide that were used as input. The long-term decline of the atmospheric CH4 growth rate from 1990 to 2006 cannot be fully explained with the simulated ecosystem emissions. However, these emissions show an increasing trend of +3.62 Tg CH4 yr−1 over 2005–2008 which can partly explain the renewed increase in atmospheric CH4 concentration during recent years.

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38

Lavarda, Sergio. "Banditry and Social Identity in the Republic of Venice. Ludovico da Porto, his Family and his Property (1567-1640)". Crime, Histoire & Sociétés 11, n. 1 (1 giugno 2007): 55–82. http://dx.doi.org/10.4000/chs.148.

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39

Nagurnas, Saulius, Valentinas Mickūnaitis, Robertas Pečeliūnas e Aurelijus Vestartas. "ANALYSIS OF CALCULATION METHODS USED FOR ACCURACY EVALUATION OF THE RESULTS OF ROAD ACCIDENT EXAMINATION". TRANSPORT 23, n. 2 (30 giugno 2008): 156–60. http://dx.doi.org/10.3846/1648-4142.2008.23.156-160.

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Abstract (sommario):

For examination of road accidents often calculations are being performed according to mathematical equations having many variables, real values of which are of stochastic nature and they depend on many accident factors. Therefore it is important to know limits of determination of final values of every being analysed parameter of car movement and their probabilistic characteristics. This paper presents some cases of simulation of some road situations by mathematical methods of calculations, which now are widely used for evaluation of accuracy of values of the calculated parameter (in this paper ‐ the braking distance). Also here is presented some analysis of these methods. The paper presents the following cases of car braking: braking with making attempts to prevent a collision with another car, braking through impact‐to‐pedestrian prevention and conventional (rectilinear) car braking. The main attention in the analysis of the mentioned road situations is paid to veracity of the car braking distance, i.e. to limits of variation of values of this parameter and also to influence of accidental factors on the final result which is being looked for. Some conclusions on the expediency of application of the described methods of calculations to analysis of road accidents are present.

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40

DUDZIAK, Agnieszka. "Perception of car sharing service in the opinion of its users". Scientific Papers of Silesian University of Technology. Organization and Management Series 2020, n. 149 (2020): 121–30. http://dx.doi.org/10.29119/1641-3466.2020.149.12.

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41

Węgrzyn, Tomasz, Bożena Szczucka-Lasota, Krzysztof Lukaszkowicz e Adam Dőring. "TIG welding of 1.4462 duplex steel in antenna and car structures". Scientific Papers of Silesian University of Technology. Organization and Management Series 2023, n. 166 (2023): 851–59. http://dx.doi.org/10.29119/1641-3466.2022.166.53.

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Abstract (sommario):

Purpose: The aim of the article was to obtain high-quality connectors for the automotive industry and antenna structures. Design/methodology/approach: For the welding joint the duplex steel and parameters of TIG welding process were chosen. The mechanical properties of the joint were carefully checked. Findings: Relations between process parameters and the quality of welds. Research limitations/implications: In the future, it can be suggested to investigate the effect of micro addition of nitrogen in gaseous shielding mixtures of the welding process. Practical implications: The development allows to obtain high-quality welded joints made of duplex steel. The solution can be implemented in the automotive industry or for the production of antenna structures. Social implications: Modifying the welding method will not affect the environment and production management methods. Originality/value: The article is addressed to manufacturers of stainless steel for automotive industry and to manufacturers of antenna instrumentation. Keywords: welding, 1.4462, duplex, automotive, antenna. Category of the paper: Research or technical papers.

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42

Cronin, John Jeremiah. "Honour, Duelling and Royal Power in Exile : a case-study of the banished Caroline Stuart Court, c.1649-c.1660". Crime, Histoire & Sociétés 17, n. 2 (1 dicembre 2013): 47–69. http://dx.doi.org/10.4000/chs.1427.

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43

Steggle, Matthew. "John Lowin and the English Theatre, 1603–1647: Acting and Cultural Politics on the Jacobean and Caroline Stage by Barbara Wooding". Comparative Drama 48, n. 4 (2014): 450–52. http://dx.doi.org/10.1353/cdr.2014.0031.

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44

Keller, David M., Wendy L. Wasmund, D. Walter Wray, Shigehiko Ogoh, Paul J. Fadel, Michael L. Smith e Peter B. Raven. "Carotid baroreflex control of leg vascular conductance at rest and during exercise". Journal of Applied Physiology 94, n. 2 (1 febbraio 2003): 542–48. http://dx.doi.org/10.1152/japplphysiol.00817.2002.

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Abstract (sommario):

We sought to test the hypothesis that the carotid baroreflex (CBR) alters mean leg blood flow (LBF) and leg vascular conductance (LVC) at rest and during exercise. In seven men and one woman, 25 ± 2 (SE) yr of age, CBR control of LBF and LVC was determined at rest and during steady-state one-legged knee extension exercise at ∼65% peak O2 uptake. The application of 5-s pulses of +40 Torr neck pressure and −60 Torr neck suction significantly altered mean arterial pressure (MAP) and LVC both at rest and during exercise. CBR-mediated changes in MAP were similar between rest and exercise ( P > 0.05). However, CBR-mediated decreases in LVC (%change) to neck pressure were attenuated in the exercising leg (16.4 ± 1.6%) compared with rest (33 ± 2.1%) and the nonexercising leg (23.7 ± 1.9%) ( P < 0.01). These data suggest CBR control of blood pressure is partially mediated by changes in leg vascular tone both at rest and during exercise. Furthermore, despite alterations in CBR-induced changes in LVC during exercise, CBR control of blood pressure was well maintained.

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45

ZDONEK, Iwona, e Bartosz MELNAROWICZ. "INTENTIONS OF ELECTRIC CAR USE – VALIDATION OF SCALES BASED ON TECHNOLOGY ACCEPTANCE THEORY". Scientific Papers of Silesian University of Technology. Organization and Management Series 2023, n. 185 (2023): 657–69. http://dx.doi.org/10.29119/1641-3466.2023.185.38.

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46

Sliż, Piotr. "The concept of a strategy of transformation of a functional organization into process organization on the example of car dealerships in Poland". Scientific Papers of Silesian University of Technology. Organization and Management Series 2018, n. 130 (2018): 529–39. http://dx.doi.org/10.29119/1641-3466.2018.130.45.

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47

Taylor, Dennis. "Texts and Traditions: Religion in Shakespeare 1592–1604, and: Shakespeare's Christianity: The Protestant and Catholic Poetics of Julius Caesar, Macbeth, and Hamlet (review)". Comparative Drama 41, n. 3 (2007): 397–401. http://dx.doi.org/10.1353/cdr.2007.0038.

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48

Hoogendoorn, Serge P., e Piet H. L. Bovy. "New Estimation Technique for Vehicle-Type-Specific Headway Distributions". Transportation Research Record: Journal of the Transportation Research Board 1646, n. 1 (gennaio 1998): 18–28. http://dx.doi.org/10.3141/1646-03.

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Abstract (sommario):

Recently, a new statistical procedure was developed that enables fast, accurate, and robust estimation of composite headway distributions, such as Branston’s generalized queueing model (GQM). Until now, the new procedure had only been applied to aggregate vehicular flow. In this paper, the estimation procedure is extended to headway observations segregated according to vehicle type and period of the day. Consequently, the parameters of a new mixed-vehicle-type headway distribution model based on Branston’s headway model can be estimated. Distinction of vehicle type and sample periods provides additional insight into the plausibility of the headway distributions and parameter values, as well as into the car-following behavior of the distinct vehicle classes varying across the different periods. The estimation procedure was applied to traffic data collected on a two-lane rural road in the Netherlands. Comparison of the estimated headway distributions with real-life data shows that headway distributions can be realistically replicated with the Pearson-III-based mixed-vehicle-type GQM. Inter-pretable differences between the morning, noon, and evening sample periods and between passenger cars, unarticulated trucks, and articulated trucks are found. In addition, passenger-car equivalents for both articulated trucks and unarticulated trucks were determined from the parameter estimates.

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49

McGinn, S. M., Y. H. Chung, K. A. Beauchemin, A. D. Iwaasa e C. Grainger. "Use of corn distillers’ dried grains to reduce enteric methane loss from beef cattle". Canadian Journal of Animal Science 89, n. 3 (1 settembre 2009): 409–13. http://dx.doi.org/10.4141/cjas08133.

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Abstract (sommario):

There are significant emissions of greenhouse gases (GHG) from agriculture, and a major source is enteric methane (CH4) from ruminants. Our study reports the impact on enteric CH4 emissions when barley grain (35% of the dietary dry matter (DM) was replaced by corn distillers’ dried grains with solubles (DDGS, adding 30 g fat kg-1 dietary DM) in the backgrounding diet of growing beef cattle. The addition of DDGS reduced CH4 emissions (g d-1) by 19.9%, and by 16.4% when adjusted for DM intake [g (DM intake)-1] or by 23.9% when adjusted for gross energy (GE) intake (% of GE intake). Adding DDGS to cattle diets reduced CH4 emissions, but the effects of higher N content of the manure on emissions of nitrous oxide and ammonia need to be accounted for to complete the evaluation of the environmental impact of feeding DDGS to feedlot cattle. Key words: Methane, beef cattle, corn distillers’ dried grains with solubles, lipid, greenhouse gas emissions, sulphur hexafluoride

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50

Dargay, J., e S. Pekkarinen. "Public Transport Pricing Policy: Empirical Evidence of Regional Bus Card Systems in Finland". Transportation Research Record: Journal of the Transportation Research Board 1604, n. 1 (gennaio 1997): 146–52. http://dx.doi.org/10.3141/1604-17.

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Abstract (sommario):

A research project is concerned with evaluating the effects of new integrated fare and ticket policies on bus use in Finland. The objective of the policy is to reduce energy consumption and the environmental effects of transport by encouraging a modal shift from cars to public transport. The scheme is based on introduction of a monthly regional bus card that offers a substantial discount on normal fares and that is valid from city center to smaller independent communities. The regional bus card is subsidized by local authorities and the state government. Estimates are presented of the fare elasticities of the demand for bus services in two regions in Finland—Oulu and Kuopio—where the regional bus card system has been introduced. The demand for bus cards and for travel with these cards is analyzed. The models used take into account different fare structures as well as the levels of fares, income, car-use costs, and service quality. The estimated elasticities indicate that in the medium-sized Finnish communities analyzed, the demand for both regional bus cards and trips when these cards are used are highly sensitive to price and income. The results are to be used in conjunction with other survey data for a preliminary assessment of the effect of the bus card system on bus patronage and car use.

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