Letteratura scientifica selezionata sul tema "Changsha guo lu chang"

We proposed a new idea for testing the thermal decay of light source under the effect of heat where the lux meter is used rather than using the integrating sphere and the thermal camera is used rather than thermocouple. The thermal decay behavior of the light is detected by using the lux meter. The thermal camera can be used to provide the temperature value as well as the temperature distribution of the measured surface which is more convenient than by using the thermocouple. This fitting model is useful for finding out the decay rate of output light under thermal effect. Full Text: PDF References E.F. Schubert and J. K. Kim, "Solid-State Light Sources Getting Smart", Science 308, 1274-1278 (2005). CrossRef E.F. Schubert, Light-emitting diodes (Cambridge University Press, 2006). CrossRef N. Narendran and Y. Gu, "Life of LED-based white light sources", J. Disp. Technol. 1, 167-171 (2005). CrossRef Y.Y. Chang, Z.Y. Ting, C.Y. Chen, T.H. Yang, and C.C. Sun, "Design of Optical Module With High Stability, High Angular Color Uniformity, and Adjustable Light Distribution for Standard Lamps", J. Disp. Technol. 10, 223-227 (2014). CrossRef C.C. Sun, C.Y. Chen, C.C. Chen, C.Y. Chiu, Y.N. Peng, Y.H. Wang, T.H. Yang, T.Y. Chung, and C.Y. Chung, "High uniformity in angular correlated-color-temperature distribution of white LEDs from 2800K to 6500K", Opt. Express 20, 6622-6630 (2012). CrossRef C.C. Sun, Q.K. Nguyen, T.X. Lee, S.K. Lin, C.S. Wu, T.H. Yang, and Y.W. Yu. "Active thermal-fuse for stopping blue light leakage of white light-emitting diodes driven by constant current", Sci. Rep. 12, 12433 (2022). CrossRef Q.K. Nguyen, Y.J. Lin, C. Sun, X.H. Lee, S.K. Lin, C.S. Wu, T.H. Yang, T.L. Wu, T.X. Lee, C.H. Chien, Y.W. Yu & C.C. "GaN-based mini-LED matrix applied to multi-functional forward lighting", Sun. Sci. Rep. 12, 6444 (2022). CrossRef T.T. N. Le, C.T. Liao, S.K. Lin, C.S. Wu, Q.K. Nguyen, T.H. Yang, Y.W. Yu, and C.C. Sun. "Study of banana preservation extension by UVC radiation in precise monitoring LED irradiation cavity", Sci. Rep. 12, 21352 (2022). CrossRef N. Narendran, Y. Gu. "Life of LED-based white light sources", J. Disp. Technol. 1, 167 (2005). CrossRef G.H. Xiao, W.J. Du, Z.Y. Wang, G.L. Chen, L.H. Zhu , Y.L. Gao , Z. Chen , Z.Q. Guo, Y.J. Lu. "Two-Dimensional Transient Temperature Distribution Measurement of GaN Light-Emitting Diode Using High Speed Camera", IEEE J. Electron Devices Soc. 9, 663-666 (2021). CrossRef N. Han, T.V. Cuong, M. Han, B.D. Ryu, S. Chandramohan, J.B. Park, J.H. Kang, Y.J. Park, K.B. Ko, H.Y. Kim, H.K. Kim, J.H. Ryu, Y.S. Katharria, C.J. Choi, C.H. Hong. "Improved heat dissipation in gallium nitride light-emitting diodes with embedded graphene oxide pattern", Nat Commun 4, 1452 (2013) CrossRef M. Cai, D.G. Yang, K.M. Tian, P. Zhang, X.P. Chen, L.L. Liu, G.Q. Zhang. "Step-stress accelerated testing of high-power LED lamps based on subsystem isolation method", Microelectron Reliab 55, 1784 (2015). CrossRef K.S. Chang, S.C. Yang, J.Y. Kim, M.H. Kook, S.Y. Ryu, H.Y. Choi, G.H. Kim. "Precise Temperature Mapping of GaN-Based LEDs by Quantitative Infrared Micro-Thermography", Sensors 12, 4648-4660 (2012). CrossRef Y. Gao, J. Jin, Y.J. Ruan, Y.L. Gao, L.H. Zhu, Z.Q. Guo, Y. Lin, Z. Chen, and Y.J. Lu. "Two-dimensional temperature distribution measurement of light-emitting diodes by micro-hyperspectral imaging-based reflected light method", Optics Express 27, 7945 (2019). CrossRef B.L. Liang , Z.L. Wang , C. Qian , Y. Ren , B. Sun , D.Z. Yang , Z. Jing and J.J. Fan. "Investigation of Step-Stress Accelerated Degradation Test Strategy for Ultraviolet Light Emitting Diodes", Materials 12, 3119 (2019). CrossRef J. Hegedüs, G. Hantos, A. Poppe. "Lifetime Modelling Issues of Power Light Emitting Diodes", Energies 13, 3370 (2020). CrossRef A. Alexeev, J.P. Linnartz, G. Onushkin, K. Arulandu, G. Martin. "Dynamic response-based LEDs health and temperature monitoring", Measurement 156, 107599 (2020). CrossRef K. Paisnik, G. Rang and T. Rang. "Life-time characterization of LEDs", Est J. Eng 17, 241 (2011). CrossRef A. Vaskuri, P. Kärhä, H. Baumgartner, O. Kantamaa, T. Pulli, T. Poikonen, E. Ikonen. "Relationships between junction temperature, electroluminescence spectrum and ageing of light-emitting diodes", Metrologia 55, S86 (2018). CrossRef

Lithium-ion batteries (LIBs) and alkaline batteries have been widely used in electric vehicles and portable electronics, dominating the energy storage market for decades,[1] but their recycling/upcycling has lagged far behind. Re/up-cycling batteries is urgently needed because it can not only preserve raw materials such as Li, Co, Ni, Mn, Al, and Cu for LIBs as well as Zn, Mn, Fe for alkaline batteries but also reduce hazardous wastes towards the environment.[2] Despite previous efforts made on re/up-cycling LIBs and alkaline batteries, there remains an urgent demand for simple, economic, environmentally benign, and energy-saving approaches. For LIB recycling, the dominated recycling methods including pyrometallurgy and hydrometallurgy are destructive and criticized of high energy consumption, undesirable economic outputs, and water contamination. By contrast, non-destructive methods such as solid-state sintering[3] and hydrothermal treatment coupled with short annealing (HT-SA) [4-5]are more promising. However, these emerged direct recycling approaches are deficient at regenerating outdated cathode materials to meet current market need. As such, upcycling (i.e., upgraded regeneration of cathodes) through surface engineering (coating[6] and doping[7-9]) or bulk reconstruction[10] has been developed. In our work, we demonstrate one upcycling approach to regenerate LiCoO2 cathode through an improved HT-SA approach in which a coating layer is prepared accompanied with the regeneration process. The upcycled cathode material shows improved electrochemical performance surpassing the pristine electrode materials. For alkaline battery recycling, the major recycling still focuses on hydrometallurgy and pyrometallurgy. Hydrometallurgical processes generally follow different steps of pre-treatment and subsequent leaching and separation of different metals by electrolysis, extraction or precipitation.[11] Another approach for treating spent alkaline battery materials is upcycling towards other applications such as supercapacitors,[12] catalysis[13], micronutrient fertilizer,[14] Mn alloy fabrication.[14] In our work, for the first time, we directly upcycle both zinc anode and Mn-based cathode for their use in rechargeable Zn-MnO2 batteries by a simple yet efficient annealing procedure. Zn was regenerated in a reductive atmosphere and the regenerated Zn shows high Coulombic efficiency and long life in symmetric cells while the regenerated Mn-based cathode shows superior performance than fresh MnO2 with regards to capacity, rate, and life. Under optimized N/P ratio, the regenerated Zn and MnO2 was paired to make rechargeable Zn-MnO2 batteries delivering excellent performance, comparable or even superior to state-of-the-art Zn-MnO2 batteries. Reference [1] Li, M.; Lu, J.; Chen, Z.; Amine, K.Advanced Materials 2018, 30, 1800561. [2] Rarotra, S.; Sahu, S.; Kumar, P.; Kim, K.-H.; Tsang, Y. F.; Kumar, V.; Kumar, P.; Srinivasan, M.; Veksha, A.; Lisak, G. ChemistrySelect 2020, 5, 6182. [3] Fan, M.; Chang, X.; Guo, Y.-J.; Chen, W.-P.; Yin, Y.-X.; Yang, X.; Meng, Q.; Wan, L.-J.; Guo, Y.-G., Energy Environ. Sci. 2021, 14 (3), 1461-1468. [4] Xu, P.; Dai, Q.; Gao, H.; Liu, H.; Zhang, M.; Li, M.; Chen, Y.; An, K.; Meng, Y. S.; Liu, P.; Li, Y.; Spangenberger, J. S.; Gaines, L.; Lu, J.; Chen, Z., Joule 2020, 4 (12), 2609-2626. [5] Shi, Y.; Chen, G.; Liu, F.; Yue, X.; Chen, Z., ACS Energy Lett. 2018, 3 (7), 1683-1692. [6] Meng, X.; Cao, H.; Hao, J.; Ning, P.; Xu, G.; Sun, Z., ACS Sustain. Chem. Eng. 2018, 6 (5), 5797-5805. [7] Wu, J.; Lin, J.; Fan, E.; Chen, R.; Wu, F.; Li, L., ACS Appl. Energy Mater. 2021, 4 (3), 2607-2615. [8] Fan, X.; Tan, C.; Li, Y.; Chen, Z.; Li, Y.; Huang, Y.; Pan, Q.; Zheng, F.; Wang, H.; Li, Q. J. Hazard. Mater. 2021, 410, 124610. [9] Xu, B.; Dong, P.; Duan, J.; Wang, D.; Huang, X.; Zhang, Y., Ceram. Int. 2019, 45 (9), 11792-11801. [10] Gaines, L.; Dai, Q.; Vaughey, J. T.; Gillard, S. Recycling 2021, 6 (2). [11] Ferella, F.; De Michelis, I.; Vegliò, F. Journal of Power Sources 2008, 183, 805. [12] Farzana, R.; Hassan, K.; Sahajwalla, V.Scientific Reports 2019, 9, 8982. [13] Gallegos, M. V.; Falco, L. R.; Peluso, M. A.; Sambeth, J. E.; Thomas, H. J.Waste Management 2013, 33, 1483. [14] Hu, X.; Robles, A.; Vikström, T.; Väänänen, P.; Zackrisson, M.; Ye, G., Journal of Hazardous Materials 2021, 411, 124928.

Abstract Objective Gastric cancer (GC) is a leading cause of cancer mortality, with ARID1A being the second most frequently mutated driver gene in GC. We sought to decipher ARID1A-specific GC regulatory networks and examine therapeutic vulnerabilities arising from ARID1A loss. Design Genomic profiling of GC patients including a Singapore cohort (>200 patients) was performed to derive mutational signatures of ARID1A inactivation across molecular subtypes. Single-cell transcriptomic profiles of ARID1A-mutated GCs were analyzed to examine tumor microenvironmental changes arising from ARID1A loss. Genome-wide ARID1A binding and chromatin profiles (H3K27ac, H3K4me3, H3K4me1, ATAC-seq) of gastric cell lines were generated to identify gastric-specific epigenetic landscapes regulated by ARID1A. Distinct cancer hallmarks of ARID1A-mutated GCs were converged at the genomic, single-cell, and epigenomic level, and targeted by pharmacological inhibition. Results We observed prevalent ARID1A inactivation across GC molecular subtypes, with distinct mutational signatures and linked to a NFKB-driven pro-inflammatory tumour microenvironment. ARID1A-depletion caused loss of H3K27ac activation signals at ARID1A-occupied distal enhancers, but unexpectedly gain of H3K27ac at ARID1A-occupied promoters in genes such as NFKB1 and NFKB2. Promoter activation in ARID1A-mutated GCs was associated with enhanced gene expression, increased BRD4 binding, and reduced HDAC1 and CTCF occupancy. Combined targeting of promoter activation and tumour inflammation via bromodomain and NFKB inhibitors confirmed therapeutic synergy specific to ARID1A-genomic status. Conclusion Our results suggest a therapeutic strategy for ARID1A-mutated GCs targeting both tumour-intrinsic (BRD4-assocatiated promoter activation) and extrinsic (NFKB immunomodulation) cancer phenotypes. Citation Format: Chang Xu, Kie Kyon Huang, Jia Hao Law, Joy Shijia Chua, Taotao Sheng, Natasha M. Flores, Melissa Pool Pizzi, Atsushi Okabe, Angie Lay Keng Tan, Feng Zhu, Vikrant Kumar, Xiaoyin Lu, Ana Morales Benitez, Benedict Shi Xiang Lian, Haoran Ma, Shamaine Wei Ting Ho, Kalpana Ramnarayanan, Chukwuemeka George Anene-Nzelu, Milad Razavi-Mohseni, Siti Aishah Binte Abdul Ghani, Su Ting Tay, Xuewen Ong, Ming Hui Lee, Yu Amanda Guo, Hassan Ashktorab, Duane Smoot, Shang Li, Anders Jacobsen Skanderup, Michael A. Beer, Roger Sik Yin Foo, Joel Shi Hao Wong, Kaushal Sanghvi, Wei Peng Yong, Raghav Sundar, Atsushi Kaneda, Shyam Prabhakar, Pawel Karol Mazur, Jaffer A. Ajani, Khay Guan Yeoh, Jimmy Bok-Yan So, Patrick Tan, Singapore Gastric Cancer Consortium. Comprehensive Molecular Phenotyping of ARID1A-deficient Gastric Cancer Reveals Pervasive Epigenomic Reprogramming and Therapeutic Opportunities [abstract]. In: Proceedings of Frontiers in Cancer Science; 2023 Nov 6-8; Singapore. Philadelphia (PA): AACR; Cancer Res 2024;84(8_Suppl):Abstract nr P28.

This paper explains about the performance of graphene nanopowder (GNP) based saturable absorber (SA) at 1.5-micron region which is prepared by dissolution in polyvinyl alcohol (PVA) polymer. Two different GNP flakes thickness (AO2-8 nm and AO4-60 nm) are tested. By applying a solution casting method, three weight ratio of GNP to PVA (12.04, 8.03 and 3.11 wt.%) have been prepared and fabricated as a composite thin film. To characterize for the SA performance, 4 mm2 area of GNP-PVA thin film is embedded in a 14 meters long ring cavity with 3 meters Erbium doped fiber (EDF) as a gain medium. Our characterization results show that the GNP-PVA thin film act as a Q-switcher which produce stable laser pulses for 12.04 wt.% with maximum repetition rate of 39.22 kHz and shortest pulse width of 11.79 µs. Meanwhile, unstable Q-switched pulses of 8.03 wt.% and 3.11 wt.% have been observed with recorded signal to noise ratio (SNR) of only 21 dB and 17 dB, respectively. The threshold pumping power for Q-switched lasing to emerge is recorded as low as 30 mW. Apparently, it shows that GNP concentration and flakes thickness in fabricated SA composite plays vital role in the performance of generated Q-switch laser, particularly at 1.5 µm region. Full Text: PDF ReferencesT. Hasan, Z. Sun, F. Wang, F. Bonaccorso, P.H. Tan, A.G. Rozhin, A.C. Ferrari, "Nanotube–Polymer Composites for Ultrafast Photonics", Adv. Mater. 21, 3874 (2009). CrossRef Q. Bao, H. Zhang, Y. Wang, Z. Ni, Y. Yan, Z.X. Shen, K.P. Loh, D.Y. Tang, "Atomic-Layer Graphene as a Saturable Absorber for Ultrafast Pulsed Lasers", Adv. Funct. Mater. 19, 3077 (2009). CrossRef Z. Luo, M. Zhou, J. Weng, G. Huang, H. Xu, C. Ye, Z. Cai, Opt. Lett. 35(21), 3709 (2010). CrossRef D. Popa, Z. Sun, T. Hasan, F. Torrisi, F. Wang, A.C. Ferrari, "Graphene Q-switched, tunable fiber laser", Appl. Phys. Lett. 98, 3106 (2011). CrossRef Y.M. Chang, H. Kim, J.H. Lee, Y. Song, "Multilayered graphene efficiently formed by mechanical exfoliation for nonlinear saturable absorbers in fiber mode-locked lasers", Appl. Phys. Lett. 97, 211102 (2010). CrossRef M. Jiang, Z. Ren, Y. Zhang, B. Lu, R. Zhang, J. Guo, Y. Zhou, J. Bai, "Passive Q-Switching with Graphene Saturable Absorber in Nd:YAG Operating at 1064nm", Mater. Sci. Forum 694, 700 (2011). CrossRef N. Hussin, M.H. Ibrahim, F. Ahmad, H. Yahaya, S.W. Harun, "Graphene Nanoplatelets (GnP)-PVA Based Passive Saturable Absorber", Telkomnika 15(2), 814 (2017). CrossRef F.C. Mat, M. Yasin, A.A. Latiff, S.W. Harun, Photonics Letters of Poland 9, 100 (2017). CrossRef E.K. Ng, K.Y. Lau, H.K. Lee, N.M. Yusoff, A.R. Sarmani, M.F. Omar, M.A. Mahdi, "L-band femtosecond fiber laser based on a reduced graphene oxide polymer composite saturable absorber", Opt. Mater. Express 11, 59 (2021). CrossRef N.H.M. Apandi, S.N.F. Zuikafly, N. Kasim, M.A. Mohamed, S.W. Harun, F. Ahmad, "Observation of dark and bright pulses in q-switched erbium doped fiber laser using graphene nano-platelets as saturable absorber", Bull. Electr. Eng. Inform. 8, 1358 (2019). CrossRef N.U.H.H.B. Zalkepali, N.A. Awang, Y.R. Yuzaile, Z. Zakaria, A.A. Latif and F. Ahmad, "Graphene Nanoplatelets as Saturable Absorber for Mode-locked Fiber Laser Generation", J. Adv. Res. Dyn. Control Syst. 12(2), 602 (2020). CrossRef X. Zhu and S. Chen, "Autoencoder-Based Transceiver Design for OWC Systems in Log-Normal Fading Channel", IEEE Photonics J. 11, 7105109 (2019). CrossRef

Ni-rich layered oxides (LiNixCoyMnzO2, x≥0.8, x+y+z=1) would fulfil the energy density requirements of the automobile industry since they offer outstanding capacities at relatively high mean voltages and sufficient power densities1-3. However, the materials still show significant capacity and voltage fade which requires substantial research. Recently we have shown that the electronic structure is the key to understand the performance but also the failure of the materials1. Thus, we intend to modify the electronic structure using anionic dopants such as Boron. Thus, homogenous B-substituted NCM811s (BNCM811_x%, x% means the x at. % of Boron) are synthesized and the materials reveal a significant change in the electronic structure as evident from x-ray photoelectron spectroscopy (XPS) and near edge x-ray absorption spectroscopy (NEXAFS). Interestingly, a shift of the so called H2-H3 peak4 to higher potentials was observed by Boron substitution and BNCM811s_2% shows relative higher initial discharge capacity (Figure 1A.) at a slightly higher mean voltage, but a lower cycling stability compared to NCM811 (Figure 1B.). The H2-H3 differential capacity peak (Figure 1C) might also include oxygen release5, which is one of the main reasons restricting the cycling stability. Near edge x-ray absorption spectroscopy (NEXAFS) shows that the H2-H3 peak corresponds to a reaction from Ni3+ to Ni2+ (upon charge) and Ni2+ to Ni3+ (upon discharge) which suggest a reaction like NiO2 ⥂ NiO + ½ O2 as the underlying process. At the same time, an Oxygen K peak at 531 eV appears in the NEXAFS spectra, which was assigned to O-O formation in the host structure of Li-rich materials6, 7. Note that the electronic structure of the materials was determined in 5 mAh/g steps over the H2-H3 peak and due to the high resolution, this process became visible for the first time. The findings suggest that dimer formation is not only a phenomenon of Li-rich materials but can also be found in Ni-rich layered oxides at high states of charge. The origin of dimer formation and oxygen release can be traced back to the electronic configuration of Ni. Charge transfer multiplet calculations reveal, that Ni2+ reacts to covalent Ni3+ upon charge (and vice versa upon discharge)1. Ni3+ has a 3d7 electronic state, whose low spin configuration is more preferred than its high spin configuration. Thus, Ni3+ is more prone to Jahn-Teller (JT) distortions and tends to form covalent bonds. Consequently, the electrons are more bound to the individual sites making a further oxidation of the transition metal almost impossible. In conclusion, Boron substitution helps us to understand the function and failure of layered oxides in Li-ion batteries on an atomistic scale and the findings can be used as a design guide for future materials. K. Kleiner, C. A. Murray, C. Grosu, B. Ying, M. Winter, P. Nagel, S. Schuppler and M. Merz, Journal of The Electrochemical Society, 2021. J. Zhao, W. Zhang, A. Huq, S. T. Misture, B. Zhang, S. Guo, L. Wu, Y. Zhu, Z. Chen and K. Amine, Advanced Energy Materials, 2017, 7, 1601266. S.-J. Yoon, K.-J. Park, B.-B. Lim, C. S. Yoon and Y.-K. Sun, Journal of the Electrochemical Society, 2014, 162, A3059. S. Jamil, G. Wang, L. Yang, X. Xie, S. Cao, H. Liu, B. Chang and X. Wang, Journal of Materials Chemistry A, 2020, 8, 21306-21316. K. Märker, P. J. Reeves, C. Xu, K. J. Griffith and C. P. Grey, Chemistry of Materials, 2019, 31, 2545-2554. E. Hu, X. Yu, R. Lin, X. Bi, J. Lu, S. Bak, K.-W. Nam, H. L. Xin, C. Jaye and D. A. Fischer, Nature Energy, 2018, 3, 690-698. K. Kleiner, B. Strehle, A. R. Baker, S. J. Day, C. C. Tang, I. Buchberger, F.-F. Chesneau, H. A. Gasteiger and M. Piana, Chemistry of Materials, 2018, 30, 3656-3667. Figure 1

In this paper, light propagation in an isotropic photonic crystal fiber as well in a silica-glass microcapillary infiltrated with a mesogenic azobenzene dye has been investigated. It appeared that light spectrum guided inside the photonic crystal fiber infiltrated with the investigated azobenzene dye depends on the illuminating wavelength of the absorption band and on linear polarization. Also, alignment of the mesogenic azobenzene dye molecules inside silica glass microcapillaries and photonic crystal fibers has been investigated. Results obtained may lead to a new design of optically tunable photonic devices. Full Text: PDF ReferencesP. Russell. St. J. "Photonic-Crystal Fibers", J. Lightwave Technol. 24, 4729 (2006). CrossRef T. Larsen, A. Bjarklev, D. Hermann, J. Broeng, "Optical devices based on liquid crystal photonic bandgap fibres", Opt. Exp. 11, 2589 (2003). CrossRef D. C. Zografopoulos, A. Asquini, E. E. Kriezis, A. d'Alessandro, R. Beccherelli, "Guided-wave liquid-crystal photonics", Lab Chip, 12, 3598 (2012). CrossRef F. Du, Y-Q. Lu, S-T. Wu, "Electrically tunable liquid-crystal photonic crystal fiber", Appl. Phys. Lett 85, 2181 (2004) CrossRef D. C. Zografopoulos, E. E. Kriezis, "Tunable Polarization Properties of Hybrid-Guiding Liquid-Crystal Photonic Crystal Fibers", J. Lightwave Technol. 27 (6), 773 (2009) CrossRef S. Ertman, M. Tefelska, M. Chychłowski, A. Rodriquez, D. Pysz, R. Buczyński, E. Nowinowski-Kruszelnicki, R. Dąbrowski, T. R. Woliński. "Index Guiding Photonic Liquid Crystal Fibers for Practical Applications", J. Lightwave Technol. 30, 1208 (2012). CrossRef D. Noordegraaf, L. Scolari, J. Laegsgaard, L. Rindorf, T. T. Alkeskjold, "Electrically and mechanically induced long period gratings in liquid crystal photonic bandgap fibers", Opt. Expr. 15, 7901 (2007) CrossRef M. M. Tefelska, M. S. Chychlowski, T. R. Wolinski, R. Dabrowski, W. Rejmer, E. Nowinowski-Kruszelnicki, P. Mergo, "Photonic Band Gap Fibers with Novel Chiral Nematic and Low-Birefringence Nematic Liquid Crystals", Mol. Cryst. Liq. Cryst. 558(1), 184 (2012). CrossRef S. Mathews, Y. Semenova, G. Farrell, "Electronic tunability of ferroelectric liquid crystal infiltrated photonic crystal fibre", Electronics Letters, 45(12), 617 (2009). CrossRef V. Chigrinov, H-S Kwok, H. Takada, H. Takatsu, "Photo-aligning by azo-dyes: Physics and applications", Liquid Crystals Today, 14:4, 1-15, (2005) CrossRef A. Siarkowska, M. Jóźwik, S. Ertman, T.R. Woliński, V.G. Chigrinov, "Photo-alignment of liquid crystals in micro capillaries with point-by-point irradiation", Opto-Electon. Rev. 22, 178 (2014); CrossRef D. Budaszewski, A. K. Srivastava, A. M. W. Tam, T. R. Woliński, V. G. Chigrinov, H-S. Kwok, "Photo-aligned ferroelectric liquid crystals in microchannels", Opt. Lett. 39, 16 (2014) CrossRef J-H Liou, T-H. Chang, T. Lin, Ch-P. Yu, "Reversible photo-induced long-period fiber gratings in photonic liquid crystal fibers", Opt. Expr. 19, (7), 6756, (2011) CrossRef T. T. Alkeskjold, J. Laegsgaard, A. Bjarklev, D. S. Hermann, J. Broeng, J. Li, S-T. Wu, "All-optical modulation in dye-doped nematic liquid crystal photonic bandgap fibers", Opt. Exp, 12 (24), 5857 (2004) CrossRef K. Ichimura, Y. Suzuki, T. Seki, A. Hosoki, K. Aoki, "Reversible change in alignment mode of nematic liquid crystals regulated photochemically by command surfaces modified with an azobenzene monolayer", Langmuir, 4, 1214 (1988) CrossRef http://www.beamco.com/Azobenzene-liquid-crystals DirectLink K. A. Rutkowska, K. Orzechowski, M. Sierakowski, "Wedge-cell technique as a simple and effective method for chromatic dispersion determination of liquid crystals", Phot. Lett, Poland, 8(2), 51 (2016). CrossRef L. Deng, H.-K. Liu, "Nonlinear optical limiting of the azo dye methyl-red doped nematic liquid crystalline films", Opt. Eng. 42, 2936-2941 (2003). CrossRef J. Si, J. Qiu, J. Guo, M. Wang, K. Hirao, "Photoinduced birefringence of azodye-doped materials by a femtosecond laser", Appl. Opt., 42, 7170-7173 (2008). CrossRef

In recent years, many attempts have been made to improve the sensory properties of SnO2, including design of sensors based on one-dimensional nanostructures of this material, such as nanofibers, nanotubes or nanowires. One of the simpler methods of producing one-dimensional tin oxide nanomaterials is to combine the electrospinning method with a sol-gel process. The purpose of this work was to produce SnO2 nanowires using a hybrid electrospinning method combined with a heat treatment process at the temperature of 600 °C and to analyze the morphology and structure of the one-dimensional nanomaterial produced in this way. Analysis of the morphology of composite one-dimensional tin oxide nanostructures showed that smooth, homogeneous and crystalline nanowires were obtained. Full Text: PDF ReferencesN. Dharmaraj, C.H. Kim, K.W. Kim, H.Y. Kim, E.K. Suh, "Spectral studies of SnO2 nanofibres prepared by electrospinning method", Spectrochim. Acta - Part A Mol. Biomol. Spectrosc. 64, (2006) CrossRef N. Gao, H.Y. Li, W. Zhang, Y. Zhang, Y. Zeng, H. Zhixiang, ... & H. Liu, "QCM-based humidity sensor and sensing properties employing colloidal SnO2 nanowires", Sens. Actuators B Chem. 293, (2019), 129-135. CrossRef W. Ge, Y. Chang, V. Natarajan, Z. Feng, J. Zhan, X. Ma, "In2O3-SnO2 hybrid porous nanostructures delivering enhanced formaldehyde sensing performance", J.Alloys and Comp. 746, (2018) CrossRef M. Zhang, Y. Zhen, F. Sun, C. Xu, "Hydrothermally synthesized SnO2-graphene composites for H2 sensing at low operating temperature", Mater. Sci. Eng. B. 209, (2016), 37-44. CrossRef Y. Zhang, X. He, J. Li, Z. Miao, F. Huang, "Fabrication and ethanol-sensing properties of micro gas sensor based on electrospun SnO2 nanofibers", Sens. Actuators B Chem. 132, (2008), 67-73. CrossRef W.Q. Li, S.Y. Ma, J. Luo, Y.Z. Mao, L. Cheng, D.J. Gengzang, X.L. Xu, S H. Yan, "Synthesis of hollow SnO2 nanobelts and their application in acetone sensor", Mater. Lett. 132, (2014), 338-341. CrossRef E. Mudra, I. Shepa, O. Milkovic, Z. Dankova, A. Kovalcikova, A. Annusova, E. Majkova, J. Dusza, "Effect of iron doping on the properties of SnO2 nano/microfibers", Appl. Surf. Sci. 480, (2019), 876-881. CrossRef P. Mohanapriya, H. Segawa, K. Watanabe, K. Watanabe, S. Samitsu, T.S. Natarajan, N.V. Jaya, N. Ohashi, "Enhanced ethanol-gas sensing performance of Ce-doped SnO2 hollow nanofibers prepared by electrospinning", Sens. Actuators B Chem. 188, (2013), 872-878. CrossRef W.Q. Li, S.Y. Ma, Y.F. Li, X.B. Li, C.Y. Wang, X.H. Yang, L. Cheng, Y.Z. Mao, J. Luo, D.J. Gengzang, G.X. Wan, X.L. Xu, "Preparation of Pr-doped SnO2 hollow nanofibers by electrospinning method and their gas sensing properties", J.Alloys and Comp. 605, (2014), 80-88. CrossRef X.H. Xu, S.Y. Ma, X.L. Xu, T. Han, S.T. Pei, Y. Tie, P.F. Cao, W.W. Liu, B.J. Wang, R. Zhang, J.L. Zhang, "Ultra-sensitive glycol sensing performance with rapid-recovery based on heterostructured ZnO-SnO2 hollow nanotube", Mater. Lett, 273, (2020), 127967. CrossRef F. Li, X. Gao, R. Wang, T. Zhang, G. Lu, Sens. "Study on TiO2-SnO2 core-shell heterostructure nanofibers with different work function and its application in gas sensor", Actuators B Chem, 248, (2017), 812-819. CrossRef S. Bai, W. Guo, J. Sun, J. Li, Y. Tian, A. Chen, R. Luo, D. Li, "Synthesis of SnO2–CuO heterojunction using electrospinning and application in detecting of CO", Sens Actuators B Chem, 226, (2016), 96-103. CrossRef H. Du, P.J. Yao, Y. Sun, J. Wang, H. Wang, N. Yu, "Electrospinning Hetero-Nanofibers In2O3/SnO2 of Homotype Heterojunction with High Gas Sensing Activity", Sensors, 17, (2017), 1822. CrossRef X. Wang, H. Fan, P. Ren, "Electrospinning derived hollow SnO2 microtubes with highly photocatalytic property", Catal. Commun. 31, (2013), 37-41. CrossRef L. Cheng, S.Y. Ma, T.T. Wang, X.B. Li, J. Luo, W.Q. Li, Y.Z. Mao, D.J Gengzang, "Synthesis and characterization of SnO2 hollow nanofibers by electrospinning for ethanol sensing properties", Mater. Lett. 131, (2014), 23-26. CrossRef P.H. Phuoc, C.M. Hung, N.V. Toan, N.V. Duy, N.D. Hoa, N.V. Hieu, "One-step fabrication of SnO2 porous nanofiber gas sensors for sub-ppm H2S detection", Sens. Actuators A Phys. 303, (2020), 111722. CrossRef A.E. Deniz, H.A. Vural, B. Ortac, T. Uyar, "Gold nanoparticle/polymer nanofibrous composites by laser ablation and electrospinning", Matter. Lett. 65, (2011), 2941-2943. CrossRef S. Sagadevan, J. Podder, "Investigation on Structural, Surface Morphological and Dielectric Properties of Zn-doped SnO2 Nanoparticles", Mater. Res. 19, (2016), 420-425. CrossRef

Abstract Objective: Pyrotinib, an oral irreversible pan-HER receptor tyrosine kinase inhibitor, showed promising efficacy and manageable safety profiles in the treatment of HER-2 positive breast cancer. Diarrhea is the most common adverse event associated with pyrotinib. This study aimed to evaluate the incidence and management of diarrhea secondary to pyrotinib in Chinese patients with HER-2 positive breast cancer. Methods: In this prospective real-world study, consecutive patients aged over 18 with HER-2 positive breast cancer and an Eastern Cooperative Oncology Group performance status (ECOG PS) of 0-2 who planned to receive pyrotinib-based regimens for at least 21 days were included. Pyrotinib-treated patients and those with preexisting gastrointestinal conditions were excluded. There were no planned management strategy or primary prophylaxis for diarrhea, while loperamide, montmorillonite powder or Golden Bifid (a live combined Bifidobacterium, Lactobacillus and Streptococcus Thermophilus tablet) were recommended. Treatment was given in accordance with routine clinical practice by investigators. For patients developed grade 3 or higher diarrhea, pyrotinib was suspended until the diarrhea improving to grade 1 or less, and secondary prophylaxis (such as loperamide, loperamide plus montmorillonite powder, or loperamide plus Golden Bifid) was administrated before pyrotinib resumption. The baseline characteristics of patients and details of diarrhea (onset time, duration, severity according to the National Cancer Institute-Common Terminology Criteria for Adverse Events version 4.03, treatment and prognosis) were collected. Results: Between August, 2020 and April, 2022, a total of 107 eligible patients were included, with a median age of 54 (range: 25-81) years old. Most patients (93.5%) had an ECOG PS of 0-1, and 51 patients (47.7%) were hormone receptor positive. A total of 46 patients (43.0%) received pyrotinib in the early stage and 61 (57.0%) in the advanced stage. Sixty-nine cases (64.5%) used pyrotinib-containing combination therapy (including 40 combined with capecitabine, 13 combined with trastuzumab, and 16 combined with other regimens), and 38 (35.5%) received pyrotinib alone. Ninety-eight cases (91.6%) reported diarrhea of any grade. Grade 1, 2 and 3 diarrhea occurred in 78 (72.9%), 9 (8.4%) and 11 (10.3%) patients, respectively. The median time to first onset of diarrhea of any grade was 2.5 (1-12) days, and the duration of first onset was 4 (1-24) days. The cumulative duration of diarrhea was 10 (1-60) days. Sixty-four, two, thirty, two patients used loperamide alone, montmorillonite powder alone, loperamide plus montmorillonite powder and loperamide plus Golden Bifid for the treatment of diarrhea, respectively. Eleven (10.3%) and seven (6.5%) patients experienced pyrotinib dose reduction and pyrotinib discontinuation. For 11 patients suffered grade 3 diarrhea, the median time to first onset of grade 3 diarrhea was 9 (4-14) days. Two, four and five patients administrated loperamide, loperamide plus Golden Bifid and loperamide plus montmorillonite powder as their secondary prophylaxis. Ten of eleven had grade 1 or 2 diarrhea after secondary prophylaxis, while one patient still suffered grade 3 diarrhea. All of them (11/11) held the pyrotinib dose. The incidence rate of constipation of all patients was 3.7%, which did not increase after treatment or secondary prophylaxis for diarrhea. Conclusion: In this study, the majority of patients developed pyrotinib associated diarrhea, and most of them were grade 1. About 10% patients reported grade 3 diarrhea, which can be managed by loperamide-based treatment and secondary prophylaxis. Table 1. Baseline characteristics of patients ECOG PS: Eastern Cooperative Oncology Group performance status; HER-2: human epidermal growth factor receptor 2. Table 2. Summary of patients developed diarrhea Table 3. Summary of patients developed grade 3 diarrhea Citation Format: Hong Liu, Li Ma, Xu Wang, Xinzhong Chang, Qi Yu, Qingfeng Huang, Chunfang Hao, Jun Liu, Jing Zhao, Shufen Li, Zhongsheng Tong, Yehui Shi, Ning Lu, Weipeng Zhao, Tong Wang, Xuchen Cao, Chen Wang, Juntian Liu, Ying Zhao, Lina Zhang, Baoliang Guo, Xin Wang, Xu Di, Chunhui Gao, Zongzhan Liu, Shuo Sun, Linwei Li. Real-world incidence and management of diarrhea secondary to pyrotinib in patients with HER-2 positive breast cancer [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P1-12-11.

The need for clean and sustainable energy sources has witnessed a sudden upsurge in recent years owing to rising environmental degradation and climate disruption brought on by an overdependence on fossil fuels [1-3]. Electrochemical energy conversion technology is a crucial complement to the storage and on-demand utilization of renewable energy resources [4-6]. Rechargeable aqueous zinc ion batteries (AZIBs) have gained a significant research upsurge in recent times owing to their attractive potential for large-scale energy storage applications. In addition to low cost and naturally abundant raw materials, AZIBs technology offers competitive electrochemical performance and compatibility with water-based electrolyte systems, thereby eliminating the safety concerns associated with prevalent lithium-based battery technology. Moreover, multivalent AZIBs offer the opportunity to attain high energy and power density by permitting multiple electron transfers during reversible electrochemical operations [7]. In the context of AZIBs, significant research efforts are being actively pursued to develop high energy density cathode materials and to address the issue of Zn dendrite formation [8]. However, the selection of stable and low-cost current collectors is equally important as it serves as a bridge between the battery components and the external circuit, thereby influencing the battery capacity and its rate capability [9-10]. In this work, we have analyzed the electrochemical behavior of potential current collectors that are used globally in battery applications, namely Ni, Al, carbon paper, Cu mesh, graphite, and stainless steel in near-neutral aqueous ZnSO4 electrolyte (pH value = 5-6). The electrochemical stability of different current collectors has been investigated using linear sweep voltammetry and chronoamperometry techniques for their application as anode and cathode collectors. Scanning electron microscopy analysis has also been performed to understand the sign of corrosion post-electrochemical study. With stability up to 2.3 V w.r.t. Zn/Zn2+, Ni has proved to be the most corrosion-resistant current collector among the tested collectors on the cathode side. Although Zn itself is sufficiently stable at the anode side than any other current collector under the ZnSO4 electrolyte environment, Ni has shown considerable stability. Nonetheless, understanding the electrochemical stability of current collectors for AZIBs is a vital step in their design and future practical applications. References [1] Anand, Abhas, and Amitabh Shankar. "Study of Coal Cake Bulk Density and Its Shear Strength for Stamp Charging Coke Making Technique at Tata Steel." Coke and Chemistry 64, no. 7 (2021): 311-321. [2] Mukherjee, Subhrajit, Soumendu Boral, Hammad Siddiqi, Asmita Mishra, and Bhim Charan Meikap. "Present cum future of SARS-CoV-2 virus and its associated control of virus-laden air pollutants leading to potential environmental threat–A global review." Journal of Environmental Chemical Engineering 9, no. 2 (2021): 104973. [3] Singh, Manish Kr, Jayashree Pati, Deepak Seth, Jagdees Prasad, Manish Agarwal, M. Ali Haider, Jeng-Kuei Chang, and Rajendra S. Dhaka. "Diffusion mechanism and electrochemical investigation of 1T phase Al-MoS2@ rGO nano-composite as a high-performance anode for sodium-ion batteries." Chemical Engineering Journal (2022): 140140. [4] Dixit, Ram Ji, Kaustava Bhattacharyya, Vijay K. Ramani, and Suddhasatwa Basu. "Electrocatalytic hydrogenation of furfural using non-noble-metal electrocatalysts in alkaline medium." Green Chemistry 23, no. 11 (2021): 4201-4212. [5] Dixit, Ram Ji, and C. B. Majumder. "CO2 capture and electro-conversion into valuable organic products: A batch and continuous study." Journal of CO2 Utilization 26 (2018): 80-92. [6] Tiwari, Pankaj Kr, and Suddhasatwa Basu. "Testing of 5x5 cm2 Solid Oxide Fuel Cell in Direct Methane." ECS Transactions 91, no. 1 (2019): 349. [7] Li, Tian Chen, Daliang Fang, Jintao Zhang, Mei Er Pam, Zhi Yi Leong, Juezhi Yu, Xue Liang Li, Dong Yan, and Hui Ying Yang. "Recent progress in aqueous zinc-ion batteries: a deep insight into zinc metal anodes." Journal of Materials Chemistry A 9, no. 10 (2021): 6013-6028. [8] Guo, Na, Wenjie Huo, Xiaoyu Dong, Zhefei Sun, Yutao Lu, Xianwen Wu, Lei Dai et al. "A review on 3D zinc anodes for zinc ion batteries." Small Methods 6, no. 9 (2022): 2200597. [9] Kühnel, Ruben-Simon, and Andrea Balducci. "Comparison of the anodic behavior of aluminum current collectors in imide-based ionic liquids and consequences on the stability of high voltage supercapacitors." Journal of Power Sources 249 (2014): 163-171. [10] Chakrabarty, Sankalpita, J. Alberto Blázquez, Tali Sharabani, Ananya Maddegalla, Olatz Leonet, Idoia Urdampilleta, Daniel Sharon, Malachi Noked, and Ayan Mukherjee. "Stability of Current Collectors Against Corrosion in APC Electrolyte for Rechargeable Mg Battery." Journal of The Electrochemical Society 168, no. 8 (2021): 080526. Figure 1

Graphene-based composites have received a great deal of attention in recent year because the presence of graphene can enhance the conductivity, strength of bulk materials and help create composites with superior qualities. Moreover, the incorporation of metal oxide nanoparticles such as Fe3O4 can improve the catalytic efficiency of composite material. In this work, we have synthesized a composite material with the combination of reduced graphene oxide (rGO), and Fe3O4 modified tissue-paper (mGO-PP) via a simple hydrothermal method, which improved the removal efficiency of the of methylene blue (MB) in water. MB blue is used as the model of contaminant to evaluate the catalytic efficiency of synthesized material by using a Fenton-like reaction. The obtained materials were characterized by SEM, XRD. The removal of materials with methylene blue is investigated by UV-VIS spectroscopy, and the result shows that mGO-PP composite is the potential composite for the color removed which has the removal efficiency reaching 65% in acetate buffer pH = 3 with the optimal time is 7 h. Keywords Graphene-based composite, methylene blue, Fenton-like reaction. References [1] Ma Joshi, Rue Bansal, Reng Purwar, Colour removal from textile effluents, Indian Journal of Fibre & Textile Research, 29 (2004) 239-259 http://nopr.niscair.res.in/handle/123456789/24631.[2] Kannan Nagar, Sundaram Mariappan, Kinetics and mechanism of removal of methylene blue by adsorption on various carbons-a comparative study, Dyes and pigments, 51 (2001) 25-40 https://doi.org/10.1016/S0143-7208(01)00056-0.[3] K Rastogi, J. N Sahu, B. C Meikap, M. N Biswas, Removal of methylene blue from wastewater using fly ash as an adsorbent by hydrocyclone, Journal of hazardous materials, 158 (2008) 531-540.https://doi.org/10.1016/j.jhazmat.2008.01. 105.[4] Qin Qingdong, Ma Jun, Liu Ke, Adsorption of anionic dyes on ammonium-functionalized MCM-41, Journal of Hazardous Materials, 162 (2009) 133-139 https://doi.org/10.1016/j.jhazmat. 2008.05.016.[5] Mui Muruganandham, Rps Suri, Sh Jafari, Mao Sillanpää, Lee Gang-Juan, Jaj Wu, Muo Swaminathan, Recent developments in homogeneous advanced oxidation processes for water and wastewater treatment, International Journal of Photoenergy, 2014 (2014). http://dx. doi.org/10.1155/2014/821674.[6] Herney Ramirez, Vicente Miguel , Madeira Luis Heterogeneous photo-Fenton oxidation with pillared clay-based catalysts for wastewater treatment: a review, Applied Catalysis B: Environmental, 98 (2010) 10-26 https://doi.org/ 10.1016/j.apcatb.2010.05.004.[7] Guo Rong, Jiao Tifeng, Li Ruifei, Chen Yan, Guo Wanchun, Zhang Lexin, Zhou Jingxin, Zhang Qingrui, Peng Qiuming, Sandwiched Fe3O4/carboxylate graphene oxide nanostructures constructed by layer-by-layer assembly for highly efficient and magnetically recyclable dye removal, ACS Sustainable Chemistry & Engineering, 6 (2017) 1279-1288 https://doi.org/10.1021/acssuschemeng.7b03635.[8] Sun Chao, Yang Sheng-Tao, Gao Zhenjie, Yang Shengnan, Yilihamu Ailimire, Ma Qiang, Zhao Ru-Song, Xue Fumin, Fe3O4/TiO2/reduced graphene oxide composites as highly efficient Fenton-like catalyst for the decoloration of methylene blue, Materials Chemistry and Physics, 223 (2019) 751-757 https://doi.org/ 10.1016/j.matchemphys.2018.11.056.[9] Guo Hui, Ma Xinfeng, Wang Chubei, Zhou Jianwei, Huang Jianxin, Wang Zijin, Sulfhydryl-Functionalized Reduced Graphene Oxide and Adsorption of Methylene Blue, Environmental Engineering Science, 36 (2019) 81-89 https://doi. org/10.1089/ees.2018.0157.[10] Zhao Lianqin, Yang Sheng-Tao, Feng Shicheng, Ma Qiang, Peng Xiaoling, Wu Deyi, Preparation and application of carboxylated graphene oxide sponge in dye removal, International journal of environmental research and public health, 14 (2017) 1301 https://doi.org/10.3390/ijerph14111301.[11] Yu Dandan, Wang Hua, Yang Jie, Niu Zhiqiang, Lu Huiting, Yang Yun, Cheng Liwei, Guo Lin, Dye wastewater cleanup by graphene composite paper for tailorable supercapacitors, ACS applied materials & interfaces, 9 (2017) 21298-21306 https://doi.org/10.1021/acsami.7b05318.[12] Wang Hou, Yuan Xingzhong, Wu Yan, Huang Huajun, Peng Xin, Zeng Guangming, Zhong Hua, Liang Jie, Ren MiaoMiao, Graphene-based materials: fabrication, characterization and application for the decontamination of wastewater and wastegas and hydrogen storage/generation, Advances in Colloid and Interface Science, 195 (2013) 19-40 https://doi. org/10.1016/j.cis.2013.03.009.[13] Marcano Daniela C, Kosynkin Dmitry V, Berlin Jacob M, Sinitskii Alexander, Sun Zhengzong, Slesarev Alexander, Alemany Lawrence B, Lu Wei, Tour James M, Improved synthesis of graphene oxide, ACS nano, 4 (2010) 4806-4814 https://doi.org/10.1021/nn1006368.[14] Zhang Jiali, Yang Haijun, Shen Guangxia, Cheng Ping, Zhang Jingyan, Guo Shouwu, Reduction of graphene oxide via L-ascorbic acid, Chemical Communications, 46 (2010) 1112-1114 http://doi. org/10.1039/B917705A [15] Gong Ming, Zhou Wu, Tsai Mon-Che, Zhou Jigang, Guan Mingyun, Lin Meng-Chang, Zhang Bo, Hu Yongfeng, Wang Di-Yan, Yang Jiang, Nanoscale nickel oxide/nickel heterostructures for active hydrogen evolution electrocatalysis, Nature communications, 5 (2014) 4695 https:// doi.org/10.1038/ncomms5695.[16] Wu Zhong-Shuai, Yang Shubin, Sun Yi, Parvez Khaled, Feng Xinliang, Müllen Klaus, 3D nitrogen-doped graphene aerogel-supported Fe3O4 nanoparticles as efficient electrocatalysts for the oxygen reduction reaction, Journal of the American Chemical Society, 134 (2012) 9082-9085 https://doi.org/10.1021/ja3030565.[17] Nguyen Son Truong, Nguyen Hoa Tien, Rinaldi Ali, Nguyen Nam Van, Fan Zeng, Duong Hai Minh, Morphology control and thermal stability of binderless-graphene aerogels from graphite for energy storage applications, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 414 (2012) 352-358 https://doi.org/ 10.1016/j.colsurfa.2012.08.048.[18] Deng Yang, Englehardt James D, Treatment of landfill leachate by the Fenton process, Water research, 40 (2006) 3683-3694 https://doi.org/ 10.1016/j.watres.2006.08.009.