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1
Anisimov, Vladimir, e Matthew Austin. "Centralized statistical monitoring of clinical trial enrollment performance". Communications in Statistics: Case Studies, Data Analysis and Applications 6, n. 4 (28 aprile 2020): 392–410. http://dx.doi.org/10.1080/23737484.2020.1758240.
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Hu, Cheng, Shui Bao Zhang, Shou Zhi Xu e Bo Xu. "Distributed Landsilde Mornitoring by Wireless Sensor Nodes". Advanced Materials Research 594-597 (novembre 2012): 1069–73. http://dx.doi.org/10.4028/www.scientific.net/amr.594-597.1069.
Abstract (sommario):
Wireless Sensor network (WSN) is an emerging technology widely applied in environmental disasters monitoring. With the constraint of computation resource, it face big challenge of stability and reliability of monitoring network. A statistical model of strain data and distributed monitoring algorithm for landslide based on WSN is studied in this paper. The strain data is modeled using variable mean of Gaussian process. Miss alarm rate and false alarm rate are introduced as critical performance parameters of landslide prediction. Comparing with centralized monitoring method, simulation result shows that distributed monitoring algorithm performs better than centralized monitoring.
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Yang, He, Jian Hai Yue e Jian Yan. "5T Information Fusion System Based on Train Technology Scheme Design". Applied Mechanics and Materials 599-601 (agosto 2014): 1229–32. http://dx.doi.org/10.4028/www.scientific.net/amm.599-601.1229.
Abstract (sommario):
On the train parts of 5T system at present all kinds of fault real-time monitoring the relevance of the weak, poor information sharing, centralized monitoring problem not in time, the system can achieve 5T effective integration of information system, information real-time delivery, 5T information fusion and 5T information fusion integrated query and statistical analysis and other functions through the acquisition of 5T system data, to train vehicle as the object of management, in order to train car number as the only connection identifier, fusion 5T information resources, to establish a global view of train vehicle safety monitoring information model. To improve the level of security early warning and fault analysis ability is of great significance.
4
Bodini, Ileana, Matteo Lancini, Simone Pasinetti e David Vetturi. "Techniques for on-board vibrational passenger comfort monitoring in public transport". ACTA IMEKO 3, n. 4 (1 dicembre 2014): 32. http://dx.doi.org/10.21014/acta_imeko.v3i4.152.
Abstract (sommario):
Traffic calming devices on urban streets, such as elevated pedestrian crossings, speed bumps and roundabouts, are increasingly used, raising a real problem in relation to the on-board comfort that passengers perceive. To measure vibrational comfort related to traffic calming devices that passengers of the public transport perceive, an acquisition system called ASGCM (Autonomous System for Geo-referenced Comfort Measurements) has been developed, taking as a reference the European regulations on rail transports. ASGCM permits to link each measurement of vibration, ground velocity and acceleration with geographical information resulting from a GPS. In this way a map of a comfort index, statistical surveys and correlation between on-board comfort and traffic calming, can be directly obtained by any Geographic Information System (GIS), able to query a centralized remote database, which was developed ad- hoc. A large number of experimental tests has been performed to define a vibrational comfort index and to collect a large dataset that allows statistically significant comparisons between different infrastructures and their characterization. The proposed technique can also be useful for diagnostics purposes, such as vehicle comparison and road maintenance state monitoring.
5
Gervais, Raymond R., e Richard Marcoux. "Saving Francophone Africa's Statistical Past". History in Africa 20 (1993): 385–90. http://dx.doi.org/10.2307/3171984.
Abstract (sommario):
Colonial administration, as every other administration, was built on the production and management of numbers: export figures (to assess the economic performance of each colony); population estimates, often falsely labeled “censuses” (to establish each colony's capacity to pay the head tax); school enrollment statistics (to establish budgets and document the road to “civilization”). French colonialism was probably one of the more centralized and number-producing systems. The regional (e.g., Dakar) and central (Paris) capitals were always requesting data for budgeting or simply for monitoring the evolution of each component of the empire.In the field of population statistics, before 1945 the process yielded very few reliable data, though a more systematic examination is required to be sure. Historically this can be explained by the evolution both of data collection and training in statistics in France during the first half of the twentieth century. The situation was well documented in the first decades of the century by Fernand Faure, a prominent member of the Société de Statistique de Paris, who noted that training in statistics was not very popular in the French civil service because no specific demand was made by higher levels of administrative or political power. Nevertheless, the Société and individuals in the Statistique Générale de France did succeed in pressing for the creation in 1922 of the Institut Supérieur de Statistique de l'Université de Paris (ISUP), but the lack of means at the institute made it virtually impossible for it to meet its training objectives.
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Khullar, Vikas, Harjit Pal Singh, Yini Miro, Divya Anand, Heba G. Mohamed, Deepali Gupta, Navdeep Kumar e Nitin Goyal. "IoT Fog-Enabled Multi-Node Centralized Ecosystem for Real Time Screening and Monitoring of Health Information". Applied Sciences 12, n. 19 (30 settembre 2022): 9845. http://dx.doi.org/10.3390/app12199845.
Abstract (sommario):
In today’s technological and stressful world, when everyone is busy in their daily routines and places blind faith in pharmaceutical advancements to protect their health, the sudden, horrifying effects of the COVID-19 pandemic have resulted in serious emotional and psychological impacts in the general population. In spite of advanced vaccination campaigns, fear and hesitation have become a part of human life since there are a number of people who do not want to take these immunity boosting vaccinations. Such people may become carriers of infectious viruses, leading to a more rapid rate of spread; therefore, this class of spreaders needs to be screened at the earliest opportunity. In this context, there is a need for advanced health monitoring systems which can assist the pharmaceutical industry to monitor and record the health status of people. To address this need and reduce the uncertainty of the situation, this study has designed and tested an Internet of Things (IoT) and Fog computing-based multi-node architecture was for real-time initial screening and recording of such subjects. The proposed system was able to record current body temperature and location coordinates along with the facial images. Further, the proposed system was able to transmit data to a cloud database using internet-connected services. An implementation and reviews-based working environment analysis was conducted to determine the efficacy of the proposed system. It was observed from the statistical analysis that the proposed IoT Fog-enabled ecosystem could be utilized efficiently.
7
Javed, Aiza, Hira Amjad e Imran Hashmi. "Drinking water quality monitoring of centralized water storage reservoirs in various zones of the National University". NUST Journal of Engineering Sciences 15, n. 2 (31 dicembre 2022): 1–9. http://dx.doi.org/10.24949/njes.v15i2.721.
Abstract (sommario):
Physico-chemical and microbiological pollutants may compromise quality of drinking water. This study aims to highlight various physico-chemical and microbial parameters of drinking water samples from centralized water storage reservoirs of National University. Major water quality parameters which were examined in this study includes pH, Electrical conductivity (EC), Turbidity, Total suspended solids (TSS), Total dissolved solids (TDS), Dissolved oxygen (DO), Residual chlorine, Hardness, Alkalinity. Moreover, microbial analysis of water samples was also carried out through Most Probable Number technique (MPN). Results show that all the physico-chemical parameters were within prescribed limits of World Health Organization and Pakistan Drinking Water Quality Standards (WHO/PDWQS) in both underground and overhead water storage reservoirs except DO ( 9.05-9.2 and 9.05-9.1 mg/L ), TSS (10-20 and 3.3-10 mg/L) and residual chlorine (0.08-0.14 and 0.19-0.28 mg/L) respectively. The MPN index values for both underground and overhead water storage reservoirs ranges between 16- >23 and 1.1-12 respectively and it shows high microbial contamination in water due to low detection of residual chlorine. The results highlight that water from centralized water storage reservoirs of National University is unfit for drinking purposes. Statistical analysis such as paired t-test also reveals that water quality parameters from underground and overhead storage reservoirs are not significantly different from each other except EC and TDS having P values <0.05. It is necessary to safeguard water contamination in water storage reservoirs by monitoring regular inspections and chemical cleaning of water storage reservoirs otherwise it will cause serious threats to well-being of the community.
Key words: water storage reservoirs, drinking water, microbial quality of water, physico-chemical parameters, paired t-test
8
Pritchett, Joshua C., Bijan J. Borah, Aakash P. Desai, Zhuoer Xie, Antoine N. Saliba, Konstantinos Leventakos, Jordan D. Coffey et al. "Association of a Remote Patient Monitoring (RPM) Program With Reduced Hospitalizations in Cancer Patients With COVID-19". JCO Oncology Practice 17, n. 9 (settembre 2021): e1293-e1302. http://dx.doi.org/10.1200/op.21.00307.
Abstract (sommario):
PURPOSE: The goal of this study was to assess the impact of an interdisciplinary remote patient monitoring (RPM) program on clinical outcomes and acute care utilization in cancer patients with COVID-19. METHODS: This is a cross-sectional analysis following a prospective observational study performed at Mayo Clinic Cancer Center. Adult patients receiving cancer-directed therapy or in recent remission on active surveillance with polymerase chain reaction–confirmed SARS-CoV-2 infection between March 18 and July 31, 2020, were included. RPM was composed of in-home technology to assess symptoms and physiologic data with centralized nursing and physician oversight. RESULTS: During the study timeframe, 224 patients with cancer were diagnosed with COVID-19. Of the 187 patients (83%) initially managed in the outpatient setting, those who did not receive RPM were significantly more likely to experience hospitalization than those receiving RPM. Following balancing of patient characteristics by inverse propensity score weighting, rates of hospitalization for RPM and non-RPM patients were 2.8% and 13%, respectively, implying that the use of RPM was associated with a 78% relative risk reduction in hospital admission rate (95% CI, 54 to 102; P = .002). Furthermore, when hospitalized, these patients experienced a shorter length of stay and fewer prolonged hospitalizations, intensive care unit admissions, and deaths, although these trends did not reach statistical significance. CONCLUSION: The use of RPM and a centralized virtual care team was associated with a reduction in hospital admission rate and lower overall acute care resource utilization among cancer patients with COVID-19.
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Sakas, Damianos P., Ioannis Dimitrios G. Kamperos, Dimitrios P. Reklitis, Nikolaos T. Giannakopoulos, Dimitrios K. Nasiopoulos, Marina C. Terzi e Nikos Kanellos. "The Effectiveness of Centralized Payment Network Advertisements on Digital Branding during the COVID-19 Crisis". Sustainability 14, n. 6 (19 marzo 2022): 3616. http://dx.doi.org/10.3390/su14063616.
Abstract (sommario):
Crises are always challenging for banking systems. In the case of COVID-19, centralized payment networks and FinTech companies’ websites have been affected by user behavior globally. As a result, there is ample opportunity for marketing managers and professionals to focus on big data from FinTech websites. This can contribute to a better understanding of the variables impacting their brand name and how to manage risk during crisis periods. This research is divided into three stages. The first stage presents the web analytics and the data retrieved from the FinTech platforms. The second stage illustrates the statistical analysis and the fuzzy cognitive mapping (FCM) performed. In the final stage, an agent-based model is outlined in order to simulate and forecast a company’s brand name visibility and user behavior. The results of this study suggest that, during crises, centralized payment networks (CPNs) and FinTech companies with high organic traffic tend to convert new visitors to actual “customers”.
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Kleyn, S. V., e S. A. Vekovshinina. "Priority risk factors related to drinking water from centralized water supply system that create negative trends in population health". Health Risk Analysis, n. 3 (settembre 2020): 49–60. http://dx.doi.org/10.21668/health.risk/2020.3.06.
Abstract (sommario):
Our research object was long-term dynamics of parameters describing drinking water from centralized water supply systems and additional cases of health disorders among population in Russia directly caused by low-quality drinking water. Our research goal was to perform hygienic assessment of priority risk factors related to drinking water and potential health disorders that could be caused by them. Our research technique was hygienic analysis of drinking water parameters as per data taken from the federal statistical form No. 18 entitled «Data on sanitary situation in a RF region» over 2000–2019, the federal information fund of social and hygienic monitoring over 2012–2019, and calculation of associated health disorders as per MG 5.1.0095–14. Specific weight of centralized water supply sources that didn’t conform to sanitary-epidemiologic requirements decreased by 4.7 % over 2000–2019 and amounted to 14.9 %. Over the last 20 years there has been a descending trend in specific weight of water samples taken from centralized water supply sources that don’t conform to sanitary requirements as per sanitary-chemical parameters (by 2.7 %) and microbiological parameters (by 4.8%). Over 2000–2019, specific weight of water distribution networks not conforming to sanitary-epidemiologic requirements decreased by 10.7 % and amounted to 15.9 % in 2019. Over the last 20 years there has been an increase in quality of drinking water taken from centralized distribution networks. Specific weight of water samples from centralized distribution networks not conforming to sanitary requirements as per microbiological and sanitary-chemical parameters fell by 6.7 % and 7.9 % respectively. In 2012–2019 in the RF hygienic parameters of drinking water quality were the most violated as per contents of bromine, silicon, chlorine, iron, sodium, lithium, magnesium, manganese, chloroform, boron, strontium, sulfides, and hydrogen sulphide. Overall, in the RF in 2019 more than 1.66 million cases of digestive diseases, cardiovascular diseases, diseases of skin and subcutaneous tissue, and other health disorders were directly related to drinking water being contaminated with chemicals and microbiological agents; it was by 13.3 % lower than in 2012 regarding morbidity associated with drinking water quality. Priority risk factors were chlorine, chlorine organic compounds (COC), ammonia, iron, manganese, arsenic, nickel, copper, boron, magnesium, and other compounds.
11
Kleyn, S. V., e S. A. Vekovshinina. "Priority risk factors related to drinking water from centralized water supply system that create negative trends in population health". Health Risk Analysis, n. 3 (settembre 2020): 49–60. http://dx.doi.org/10.21668/health.risk/2020.3.06.eng.
Abstract (sommario):
Our research object was long-term dynamics of parameters describing drinking water from centralized water supply systems and additional cases of health disorders among population in Russia directly caused by low-quality drinking water. Our research goal was to perform hygienic assessment of priority risk factors related to drinking water and potential health disorders that could be caused by them. Our research technique was hygienic analysis of drinking water parameters as per data taken from the federal statistical form No. 18 entitled «Data on sanitary situation in a RF region» over 2000–2019, the federal information fund of social and hygienic monitoring over 2012–2019, and calculation of associated health disorders as per MG 5.1.0095–14. Specific weight of centralized water supply sources that didn’t conform to sanitary-epidemiologic requirements decreased by 4.7 % over 2000–2019 and amounted to 14.9 %. Over the last 20 years there has been a descending trend in specific weight of water samples taken from centralized water supply sources that don’t conform to sanitary requirements as per sanitary-chemical parameters (by 2.7 %) and microbiological parameters (by 4.8%). Over 2000–2019, specific weight of water distribution networks not conforming to sanitary-epidemiologic requirements decreased by 10.7 % and amounted to 15.9 % in 2019. Over the last 20 years there has been an increase in quality of drinking water taken from centralized distribution networks. Specific weight of water samples from centralized distribution networks not conforming to sanitary requirements as per microbiological and sanitary-chemical parameters fell by 6.7 % and 7.9 % respectively. In 2012–2019 in the RF hygienic parameters of drinking water quality were the most violated as per contents of bromine, silicon, chlorine, iron, sodium, lithium, magnesium, manganese, chloroform, boron, strontium, sulfides, and hydrogen sulphide. Overall, in the RF in 2019 more than 1.66 million cases of digestive diseases, cardiovascular diseases, diseases of skin and subcutaneous tissue, and other health disorders were directly related to drinking water being contaminated with chemicals and microbiological agents; it was by 13.3 % lower than in 2012 regarding morbidity associated with drinking water quality. Priority risk factors were chlorine, chlorine organic compounds (COC), ammonia, iron, manganese, arsenic, nickel, copper, boron, magnesium, and other compounds.
12
Ma, Chao, Sen Dong, Jijian Lian e Xiulan Pang. "Multi-Objective Sizing of Hybrid Energy Storage System for Large-Scale Photovoltaic Power Generation System". Sustainability 11, n. 19 (1 ottobre 2019): 5441. http://dx.doi.org/10.3390/su11195441.
Abstract (sommario):
Hybrid energy storage systems (HESS) are an effective way to improve the output stability for a large-scale photovoltaic (PV) power generation systems. This paper presents a sizing method for HESS-equipped large-scale centralized PV power stations. The method consists of two parts: determining the power capacity by a statistical method considering the effects of multiple weather conditions and calculating the optimal energy capacity by employing a mathematical model. The method fully considers the characteristics of PV output and multiple kinds of energy storage combinations. Additionally, a pre-storage strategy that can further improve stability of output is proposed. All of the above methods were verified through a case study application to an 850 MW centralized PV power station in the upstream of the Yellow river. The optimal hybrid energy storage combination and its optimization results were obtained by this method. The results show that the optimal capacity configuration can significantly improve the stability of PV output and the pre-storage strategy can further improve the target output satisfaction rate by 8.28%.
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Shekhar Nigam, Dr. Sanjay Kumar Tiwari. "Bayesian Regularization (BR) Optimization Based DDoS Detection for SDN and Next Generation Communication Network". Tuijin Jishu/Journal of Propulsion Technology 44, n. 4 (5 novembre 2023): 4104–16. http://dx.doi.org/10.52783/tjjpt.v44.i4.1623.
Abstract (sommario):
The rapid evolution of communication networks, particularly Software-Defined Networking (SDN) and next-generation communication infrastructures, has introduced new challenges in securing these dynamic and complex environments. Among the most persistent threats are Distributed Denial of Service (DDoS) attacks, which can disrupt critical services and inflict severe economic and operational damages. To combat these threats, novel and adaptive DDoS detection mechanisms are crucial. This paper proposes a Bayesian Regularization (BR) optimization-based approach for DDoS detection in SDN and next-generation communication networks. Bayesian Regularization is a statistical technique that combines the strength of Bayesian analysis with optimization methodologies, enabling the model to adapt to changing network conditions and attack strategies. This approach leverages the inherent advantages of SDN, such as centralized control and real-time network monitoring, to enhance the accuracy and timeliness of DDoS detection.
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Novikova, Yuliya A., K. B. Friedman, V. N. Fedorov, A. A. Kovshov, N. A. Tikhonova e I. O. Myasnikov. "About the question of the assessment of the drinking water quality in centralized water systems in the current conditions". Hygiene and sanitation 99, n. 6 (29 luglio 2020): 563–68. http://dx.doi.org/10.47470/0016-9900-2020-99-6-563-568.
Abstract (sommario):
Introduction. Regulation of drinking water quality is a very important area of health care and improving the quality of life of the population of the Russian Federation.The aim of this work is the development a model for the assessment of the drinking water quality and calculating the share of the population, including urban, provided with high-quality drinking water from centralized water supply systems, taking into account new methodological approaches to the evaluation of the quality of drinking water using the example of water supply to settlements in the Leningrad Region. Material and methods. The data on the organization of centralized cold water supply systems and monitoring systems for drinking water quality and the results of laboratory studies of drinking water quality in the cities of Volkhov, Svetogorsk, Slantsy, Tosno were studied. Statistical processing of the results was performed, the categories of quality of drinking water supplied to the population were determined, the number of the population provided with high-quality drinking water from the water supply system was calculated in accordance with Guidelines 2.1.4.0143-19.Results. In 2018, 100% of the population was provided with quality drinking water only in the city of Slantsy. In the city of Tosno, this index reached of 83.5%. In the cities of Volkhov and Svetogorsk, drinking water was rated as low-quality. But it is worth noting that in the cities of Volkhov and Slantsy laboratory tests were carried out at 2 points, in the city of Svetogorsk - only at the 1 point, which, given the number of residents, is not enough. For an objective assessment of the state of drinking water and the development of measures aimed at improving its quality, it is necessary to increase the number of monitoring points, as well as to include the results of control and supervision measures and production laboratory control conducted by water supply organizations in the volume of laboratory information.Conclusion. The proposed model allows us to assess the drinking water quality in centralized water supply systems and the proportion of the population, including urban, provided with quality drinking water at the level of the water supply system, settlement, municipal district (urban district), subject of the Russian Federation
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Fridman, K. B., Yuliia A. Novikova e A. S. Belkin. "ON THE ISSUE OF THE USE OF HEALTH RISK ASSESSMENT TECHNIQUES FOR HYGIENIC CHARACTERISTICS OF WATER SUPPLY SYSTEMS". Hygiene and sanitation 96, n. 7 (27 marzo 2019): 686–89. http://dx.doi.org/10.18821/0016-9900-2017-96-7-686-689.
Abstract (sommario):
The study was aimed to assess the dynamics of risk indices for population health at main stages of surface source water treatment for centralized domestic water supply of the Leningrad region communities. Practical application issues of calculation procedure for the integrated assessment of drinking water from centralized water supply by chemical safety indices, as exemplified by Vsevolozhsk communities (Leningrad region) water supply from the Lake Ladoga and the Neva River as water sources, are discussed. Results of quality monitoring of water from centralized domestic supply system at the stage of water intake, at the output of water treatment, and in the distributing system, accomplished by Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing administration and Center of hygiene and epidemiology in the Leningrad region were used as study materials. The following study techniques were used: descriptive statistics, comparative analysis, risk assessment, generalization. Microsoft Excel program was used for analysis and statistical treatment. Integral water quality index appears to be quite an informative integrated index of the efficacy of the water treatment, however, the same index value can be derived by various combinations of risk values of reflex-olfactory, non-carcinogenic and carcinogenic effects. Therefore, during the calculations, a “risk index of the effects of chronic exposure” was introduced with a view to distinguishing them from effects caused by the adverse organoleptic properties of water (reflex-olfactory effects). For the population these properties are the main reason for refusal from the use drinking water, and at the same time they are physiological, lying outside the pathology. The risk of effects of chronic exposure, carcinogenic and non-carcinogenic, expresses the probability of the development of pathology in time, but not the likelihood of an immediate refusal to use drinking water due to its unsatisfactory organoleptic qualities.
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Kovshov, Aleksandr A., Yuliya A. Novikova, Vladimir N. Fedorov, Nadezhda A. Tikhonova, Igor O. Myasnikov e Roman V. Buzinov. "Determination of the microbial risk degree to health of the population provided with centralized water supply". Hygiene and sanitation 102, n. 8 (9 ottobre 2023): 768–74. http://dx.doi.org/10.47470/0016-9900-2023-102-8-768-774.
Abstract (sommario):
Introduction. Modern methodological approaches make it possible to assess the risk of waterborne bacterial intestinal infections, taking into account both the sanitary and hygienic conditions of water used by the population and the level of communal improvement of the territory.
The purpose of the study was to assess the degree of epidemic danger of bacterial intestinal infections associated with the conditions of centralized drinking and household water supply, using the example of the subjects of the Northwestern Federal District.
Materials and methods. The study tested the data of the federal statistical observation form No. 18 “Information on the sanitary condition of the subject”, the federal information fund of social and hygienic monitoring, and the Unified Interdepartmental Information and Statistical System. We analyzed the materials for 2022 in eleven subjects of the Northwestern Federal District. Method MR 2.1.10.0031-11 was taken as the basis for microbial risk assessment.
Results. The Republic of Karelia, Vologda, Arkhangelsk, and Novgorod regions are characterized by an average degree of microbial risk in terms of the proportion of drinking water samples in the distribution network, in which generalized coliform bacteria were found; Novgorod region and the Republic of Karelia have a high degree of risk for E. coli. The lowest number of population provided with centralized water supply, corresponding to a high degree of microbial risk, was found in the Nenets Autonomous Okrug. This region is also characterized by the lowest average daily water consumption per capita.
Limitations. The study tested the data on the subjects of the North-Western Federal District in 2022, the quality of drinking water was assessed only according to the results of laboratory studies conducted by the Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing.
Conclusion. Most regions of the Russian North-West are characterized by an average degree of microbial risk, except for St. Petersburg, where a low degree of risk is established. The use of an alternative variant of risk ranking by 5 degrees (low, slightly increased, increased, significantly increased, high) showed that in the Republic of Karelia, Arkhangelsk and Vologda regions, and Nenets Autonomous Okrug, there is a significantly elevated degree of microbial risk.
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Wang, Yanping, Pinliang Dong, Shunbao Liao, Yueqin Zhu, Da Zhang e Na Yin. "Urban Expansion Monitoring Based on the Digital Surface Model—A Case Study of the Beijing–Tianjin–Hebei Plain". Applied Sciences 12, n. 11 (24 maggio 2022): 5312. http://dx.doi.org/10.3390/app12115312.
Abstract (sommario):
Although urban expansion statistics have been widely carried out, large-scale and rapid monitoring is still worth doing in order to improve the efficiency of statistics, as well as make up for the omissions and deficiencies of construction expansion statistics with multi-year intervals. This paper presents a study of urban expansion in the Beijing–Tianjin–Hebei plain based on ALOS Global Digital Surface Model “ALOS World 3D-30 m” (AW3D30 DSM), Shuttle Radar Topography Mission (SRTM) DSM, and Landsat 7 ETM+ images. Through the evaluation of errors and the elimination of non-building changes, a relatively objective result is derived. The neighborhood block statistics of the construction height expansion reveal that from 2000 to 2009, the largest centralized construction expansion mainly occurred between the Second Ring Road and the Fifth Ring Road of Beijing, followed by Yizhuang, Shunyi, Tianjin Central City, and Langfang. Zonal statistics also show a significant imbalance in the expansion of construction in the counties of the Beijing–Tianjin–Hebei plain. For example, Chaoyang, Dongcheng, Xicheng, Xuanwu, Chongwen, Nankai, Heping, and Hexi have a larger construction expansion; however, other counties present a relatively slow rate of building expansion. Furthermore, the correlation coefficient between the statistical average building height expansion per unit area (ABHE, by our method) and the actual average completed building floor space per unit area (ACBFS) derived from the Beijing Statistical Yearbook (BSY) is 0.9436, which proves that this method is feasible. With the continuous improvement of DSM data quality in the future, the method proposed in this paper can provide rapid and large-scale statistics to study more urban construction expansion in the world.
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Ciommi, Mariateresa, Francesco Chelli, Margherita Carlucci e Luca Salvati. "Urban Growth and Demographic Dynamics in Southern Europe: Toward a New Statistical Approach to Regional Science". Sustainability 10, n. 8 (5 agosto 2018): 2765. http://dx.doi.org/10.3390/su10082765.
Abstract (sommario):
Metropolitan growth in Europe has resulted in drastic changes of urban forms, socio-spatial structures and land-use patterns due to sequential processes of urbanization, suburbanization and re-urbanization. To assess latent shifts from mono-centric models towards more disarticulated and decentralized settlement configurations, the present study evaluates spatio-temporal patterns of growth between the 1920s and the 2010s in three Mediterranean cities with different structure and functions (Barcelona: compact and moderately polycentric; Rome: dispersed, medium-density; Athens: mono-centric, hyper-compact). To identify and characterize long-term urban transformations, an original approach was illustrated in this study, based on a multivariate analysis of 13 indicators resulting from descriptive statistics and linear regression modeling the relationship between population density and distance from inner cities. The empirical results of this study indicate that Barcelona, Rome and Athens have experienced different urbanization cycles, characterized by a (more or less) concentrated distribution of population along urban gradients. Despite similarities in demographic dynamics and planning practices, these processes have determined (i) a mostly centralized growth in Barcelona, (ii) a relatively dispersed and discontinuous spatial structure in Rome, and (iii) a steep decline of population density with the distance from downtown Athens. Compact urban expansion, population decline and urban de-concentration were finally assessed using the analytical approach proposed in this study.
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Baker, H. Kent, Satish Kumar, Sisira Colombage e Harsh Partap Singh. "Working capital management practices in India: survey evidence". Managerial Finance 43, n. 3 (13 marzo 2017): 331–53. http://dx.doi.org/10.1108/mf-07-2016-0186.
Abstract (sommario):
Purpose The purpose of this paper is to investigate the working capital management (WCM) practices adopted by Indian firms listed on the National Stock Exchange (NSE). Design/methodology/approach Using a questionnaire, the authors gather data from 110 financial managers and use various statistical techniques to test for statistical significance. Findings The evidence shows that the majority (54.5 percent) of sample firms follow a moderate approach in financing their activities, which involves a trade-off between liquidity and profitability. Respondents tend to use an informal approach for WCM and consider receivables management as the most important component of WCM. In terms of WCM monitoring and financial measures, respondents mainly consider the cash conversion cycle and net working capital. Indian firms tend to use centralized cash management and rely heavily on material requirement planning (MRP) and enterprise resource planning (ERP) for proper inventory management. Research limitations/implications Tests involving firm size, foreign sales, and average age do not differ significantly between the NSE-listed firms and the sample firms. This evidence lessens concerns of non-response bias and the ability to generalize the findings to Indian firms. Originality/value By updating and extending previous research on WCM, this study fills a gap in the literature by providing insights into practices adopted by Indian firms in managing WCM and its components.
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Fedorov, Vladimir N., E. V. Zibarev, Yu A. Novikova, A. A. Kovshov, K. B. Fridman e O. V. Slusareva. "HYGIENIC ASSESSMENT OF HEALTH RISK FACTORS FOR POPULATION OF MEGAPOLISIS’SATELLITE TOWNS BY THE EXAMPLE OF LENINGRAD REGION". Hygiene and sanitation 96, n. 7 (27 marzo 2019): 614–19. http://dx.doi.org/10.18821/0016-9900-2017-96-7-614-619.
Abstract (sommario):
Minor towns with population size of 50-100 thousand people are much rarely studied in regards of the ecological-hygienic assessment of human environment, in spite of the fact that they are characterized by specific ecological problems. The objective of the study was the hygienic assessment of the impact of urban environment on population health status in Tikhvin and Gatchina towns of the Leningrad region. Morbidity rate in the population of Tikhvin and Gatchina in 2005-2015, atmospheric emissions of industrial enterprises, findings on monitoring for both atmospheric air pollution and centralized drinking water supply, as well as motor transport noise levels were studied. Population health risk stipulated by industrial emissions and noise exposure was calculated. Statistical data treatment with correlation analysis of the relationship between environmental pollution indices and population morbidity was carried out. The study revealed increased atmospheric air pollutant concentrations in Gatchina, which might be connected with motor transport effect. Acute non-carcinogenic risk levels resulting from air pollutants are on the borderline of the admissible level, while in Tikhvin town those values are significantly lower. Estimated concentrations of atmospheric pollutants produced by industrial emissions are by 1.5-2 times lower than the actual levels shown by monitoring. Noise levels and predicted health risks in Gatchina are on the borderline of the admissible level, while in Tikhvin they are significantly reduced. The statistically significant gain in the general primary morbidity rate indices due to respiratory diseases in Gatchina town, correlated with atmospheric air pollution, was revealed. Our study showed that despite the presence of large industrial enterprises in studied towns, motor transport proved to be the key factor that forms air pollution and noise load, more typical of large cities.
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Ogay, М. Yu. "Problems of Quality Assurance for Socio-Economic Data at Local Level". Statistics of Ukraine 89, n. 2-3 (24 novembre 2020): 22–31. http://dx.doi.org/10.31767/su.2-3(89-90)2020.02-03.03.
Abstract (sommario):
The process of decentralization involves the enhanced interest of local power bodies in carrying out an effective benchmarking at local level, along with the increasing demand on relevant and reliable information on the development of territorial communities. Today, the local self-government faces financial and technical limitations in creating effective local systems for information support. It follows that the only way of producing a unified statistical support as a tool for performance analysis at local level is developing a centralized information system.
The article contains an analysis of the quality of the existing centralized information system, which viability is supported by the Association of Ukrainian Cities. The computerized system of municipal statistics, developed in Ukraine, is an online system for collection, storage and processing of information on the core areas of life activities of territorial communities and self-government bodies. The system is based on the advanced principles of creation and operation of information products, whereas its organization, structure and technological tooling on the whole is compliant with analogous systems used in other spheres and in some other countries. However, most part of the indicators for which the data are collected and processed by the system does not comply with the core dimensions of quality, namely: relevance (topicality) / compliance with user needs; accuracy/reliability of estimated figures; timeliness and punctuality of production and publishing of processed data; accessibility and comprehensibility/clearness of metadata; comparability; consistency/coherence of indicators in space and time.
The author’s study laid the basis for the elaborated recommendations on quality enhancement for the data collected at municipal level. A reliable information system must meet the following requirements: compliance of the system’s purpose and functions with user needs; coverage of the maximal number of administrative-territorial units; free access for users by hierarchical approach; availability of computerized data conversion; optimization of the set of primary, secondary and summary indicators and metadata that are developed by standard forms; use of advanced methods for data analysis and presentation given well-developed monitoring capabilities; viability and provision of appropriate professional support. If implemented, these recommendations will enable to form the solid information basis for comprehensive monitoring of life activities of cities and local communities in Ukraine.
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Ogay, М. Yu. "Problems of Quality Assurance for Socio-Economic Data at Local Level". Statistics of Ukraine 89, n. 2-3 (24 novembre 2020): 22–31. http://dx.doi.org/10.31767/su.2-3(89-90)2020.02-03.03.
Abstract (sommario):
The process of decentralization involves the enhanced interest of local power bodies in carrying out an effective benchmarking at local level, along with the increasing demand on relevant and reliable information on the development of territorial communities. Today, the local self-government faces financial and technical limitations in creating effective local systems for information support. It follows that the only way of producing a unified statistical support as a tool for performance analysis at local level is developing a centralized information system.
The article contains an analysis of the quality of the existing centralized information system, which viability is supported by the Association of Ukrainian Cities. The computerized system of municipal statistics, developed in Ukraine, is an online system for collection, storage and processing of information on the core areas of life activities of territorial communities and self-government bodies. The system is based on the advanced principles of creation and operation of information products, whereas its organization, structure and technological tooling on the whole is compliant with analogous systems used in other spheres and in some other countries. However, most part of the indicators for which the data are collected and processed by the system does not comply with the core dimensions of quality, namely: relevance (topicality) / compliance with user needs; accuracy/reliability of estimated figures; timeliness and punctuality of production and publishing of processed data; accessibility and comprehensibility/clearness of metadata; comparability; consistency/coherence of indicators in space and time.
The author’s study laid the basis for the elaborated recommendations on quality enhancement for the data collected at municipal level. A reliable information system must meet the following requirements: compliance of the system’s purpose and functions with user needs; coverage of the maximal number of administrative-territorial units; free access for users by hierarchical approach; availability of computerized data conversion; optimization of the set of primary, secondary and summary indicators and metadata that are developed by standard forms; use of advanced methods for data analysis and presentation given well-developed monitoring capabilities; viability and provision of appropriate professional support. If implemented, these recommendations will enable to form the solid information basis for comprehensive monitoring of life activities of cities and local communities in Ukraine.
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Dimech, Wayne, Marina Karakaltsas e Giuseppe A. Vincini. "Comparison of four methods of establishing control limits for monitoring quality controls in infectious disease serology testing". Clinical Chemistry and Laboratory Medicine (CCLM) 56, n. 11 (25 ottobre 2018): 1970–78. http://dx.doi.org/10.1515/cclm-2018-0351.
Abstract (sommario):
Abstract Background: A general trend towards conducting infectious disease serology testing in centralized laboratories means that quality control (QC) principles used for clinical chemistry testing are applied to infectious disease testing. However, no systematic assessment of methods used to establish QC limits has been applied to infectious disease serology testing. Methods: A total of 103 QC data sets, obtained from six different infectious disease serology analytes, were parsed through standard methods for establishing statistical control limits, including guidelines from Public Health England, USA Clinical and Laboratory Standards Institute (CLSI), German Richtlinien der Bundesärztekammer (RiliBÄK) and Australian QConnect. The percentage of QC results failing each method was compared. Results: The percentage of data sets having more than 20% of QC results failing Westgard rules when the first 20 results were used to calculate the mean±2 standard deviation (SD) ranged from 3 (2.9%) for R4S to 66 (64.1%) for 10X rule, whereas the percentage ranged from 0 (0%) for R4S to 32 (40.5%) for 10X when the first 100 results were used to calculate the mean±2 SD. By contrast, the percentage of data sets with >20% failing the RiliBÄK control limits was 25 (24.3%). Only two data sets (1.9%) had more than 20% of results outside the QConnect Limits. Conclusions: The rate of failure of QCs using QConnect Limits was more applicable for monitoring infectious disease serology testing compared with UK Public Health, CLSI and RiliBÄK, as the alternatives to QConnect Limits reported an unacceptably high percentage of failures across the 103 data sets.
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Oksiiuk, Oleksandr, Larysa Myrutenko e Yanina Shestak. "PRACTICAL INTRODUCTION OF INFORMATION SYSTEMS BASED ON ASSESSMENT OF EXTERNAL INFLUENCES". Information systems and technologies security, n. 1 (1) (2019): 27–35. http://dx.doi.org/10.17721/ists.2019.1.27-35.
Abstract (sommario):
The article highlighted the advantage of information systems in front of centralized systems in terms of ensuring the security of network infrastructure, data transmitted, and procedures used in the software environment of the complex. It was pointed out the technical simplicity of the methods of expansion of information systems and, accordingly, their scalability. A multilevel energy balance scheme and computing resources of the information system infrastructure, based on the optimization of the task graph, have been developed. The methods of estimating the optimization of the graph of tasks, which are based on the indicators of the normalized graph normalized distribution of energy, are determined. The results of mathematical modeling in comparison with statistical data for such methods of working with task graphs as calculations by hierarchical structure, graph split algorithms, methods based on algebraic theory of graphs, structuring of "Diamond Dags" type. The analysis was conducted for such types of distribution as uniform distribution, binomial distribution, geometric distribution. The results of the comparison point to a sufficiently upstart prediction accuracy at the level of mathematical modeling. In most cases, the value of the maximum deviation, presented as a relative error, between simulation results and statistical data remains within 10%, which shows the adequacy of the simulation. Nevertheless, for the four pairs of functions of the length of the normalized graph and the normalized energy distribution, the maximum deviation is greater than 10%, indicating the need for a revision of the model and further statistical studies. It is proposed to use in organizing the protection of resources of the information system of clusterization methods, which allow to construct a transparent scheme of functioning of the complex and to construct monitoring algorithms
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Fei, Wenjun, Zhijia Jin, Jienan Ye, Prasanna Divigalpitiya, Takeru Sakai e Chengkang Wang. "DISASTER CONSEQUENCE MITIGATION AND EVALUATION OF ROADSIDE GREEN SPACES IN NANJING". Journal of Environmental Engineering and Landscape Management 27, n. 1 (20 marzo 2019): 49–63. http://dx.doi.org/10.3846/jeelm.2019.9236.
Abstract (sommario):
The extensive layout of roadside green spaces make them important green disaster mitigation nodes in high-density areas of any city; hence, further improvements in their disaster mitigation functions would make the urban disaster prevention system more effective. In the present research, different types of roadside green spaces in the Gulou district of Nanjing were identified to establish a highly efficient urban disaster refuge green space system. A total of 35 built-up roadside green spaces were employed as the study site, and for field investigation and statistical analysis, 21 factors were selected from the aspects of spatial form, functional facilities, and surrounding environment. According to their disaster mitigation abilities, cluster analysis classified these roadside green spaces into four categories: complete type, potential type, centralized type, and broad type. Finally, by analyzing the characteristics of different types of roadside green spaces, corresponding optimization strategies were proposed. In comparison to previous investigations, our study focused on the quantitative evaluation of disaster mitigation and risk protection function of roadside green spaces. In the future, the obtained results will serve as important scientific references to the planning and construction of green spaces in high-density areas of Nanjing, China.
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Oberio, Elnelyn C., e Markh B. Jamandre. "Police CrimeStat". Philippine Social Science Journal 3, n. 2 (16 novembre 2020): 179–80. http://dx.doi.org/10.52006/main.v3i2.152.
Abstract (sommario):
This project aimed to automate the manual entry of the incident reports of the Philippine National Police. The system is projected to provide effective monitoring and updated statistical reports that will be used for decision-making processes. All police stations within the designated area will have an installed application that is centralized nationwide. Thus, data analysis would be easier and useful for law enforcement agencies for long-term crime bust programs. The system has the following specific objectives: first is to provide easier access to blotter reports, to improve decision making with interactive maps, to promote information sharing, and lastly, to offer statistical information of incidents. Evaluation of incident reports by an authorized officer is necessary before encoding them into the system. The data that the system needs includes the following: complainant and suspect's name(s), case details, and the type of offense. Inputted incident reports can be seen by the central office and other police stations; however, data manipulation is accessed only in the central office. The system can search and display case details in a printable format based on the user's specified query. By utilizing the Google map application program interface (API), the user can quickly locate and see the crime's exact location. This particular feature is challenging because there is a need to structure a detailed data mining design to promptly generate reliable reports. Once data are encoded in the system, the central office can create reports according to their needs. The system development started with data gathering by interviewing the Non-Uniform Personnel of Murcia Police station and performed the requirements analysis for the system.
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Pritchett, Joshua, Jonas Paludo, Qian Shi, Nandita Khera, Zachary Yetmar, John W. Wilson, Rozalina McCoy et al. "Decreasing the burden of febrile neutropenia through dynamic remote patient monitoring: The DEFeNDER program." Journal of Clinical Oncology 41, n. 16_suppl (1 giugno 2023): 1535. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.1535.
Abstract (sommario):
1535 Background: Ambulatory management of select patients with febrile neutropenia (FN) may substantially decrease patients’ burden of illness and improve their quality of life, and is recommended by American Society of Clinical Oncology (ASCO) guidelines. However, in the United States, inpatient management remains the universal standard. We hereby report the health care utilization associated with the DEFeNDR remote patient monitoring (RPM) program, which leverages technology and virtual centralized nurse monitoring to facilitate ambulatory management of FN as an alternative to hospital-based care. Methods: Adult patients with cancer hospitalized with FN were assessed daily for eligibility to participate in the DEFeNDR program. Eligibility criteria included MASCC score >21 (per ASCO guidelines), and clinical judgment of the attending provider. Patients receiving cellular therapy (CAR-T, BMT) in the prior 100 days were excluded. Eligible patients agreeing to participate in the 30-day program were provided a kit containing cellular-enabled, pre-connected devices to facilitate monitoring, including twice-daily vital signs and electronic symptom questionnaires. Data were EHR-integrated in real-time and embedded decision trees facilitated alerts for adverse trends. RPM nurses responded to alerts and escalated care as indicated by pre-specified care pathways. Program assessment was performed at 20 weeks after full implementation. The primary outcome was the mean proportion of evaluable days spent inpatient (mPEDI) within 30 days of eligibility compared between those who participated in the program vs. those who declined. Results: 35 patients were offered participation in the DEFeNDR program. Of these, 17 participated and 18 declined. Baseline characteristics are provided. Participating patients experienced mPEDI of 6.9% (Standard Error [SE], 3.7%), compared with 17.7% (SE, 3.6%) for patients who declined participation. Due to small sample size, this difference (10.8%) did not reach statistical significance (Wilcoxon Rank Sums p-value, 0.15). 30-day mortality did not differ between groups. Mean inpatient days were also lower for patients participating in the program. Additionally, when readmitted, patients participating in RPM experienced a trend toward shorter length of stay and lower rates of intensive care unit utilization. Conclusions: A trend towards decreased burden of inpatient care is evident among patients participating in the DEFeNDR program. Further studies are warranted to assess comparative effectiveness of this model vs usual care.[Table: see text]
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Nayak, Smrutiranjan, Sanjeeb Kumar Kar, Subhransu Sekhar Dash, Pradeep Vishnuram, Sudhakar Babu Thanikanti e Benedetto Nastasi. "Enhanced Salp Swarm Algorithm for Multimodal Optimization and Fuzzy Based Grid Frequency Controller Design". Energies 15, n. 9 (27 aprile 2022): 3210. http://dx.doi.org/10.3390/en15093210.
Abstract (sommario):
In the present study, an Enhanced SSA (ESSA) has been proposed where the parameter of the SSA technique, which balances the exploration and exploitation phases, has been modified. Additionally, the variable scaling factor is engaged to regulate the salp’s position during the search procedure to minimize the random movement of salps. To demonstrate the effectiveness of the enhanced SSA (ESSA), a set of multimodal test functions are engaged. The statistical outcomes demonstrate that ESSA profits from local optima evasion and quick convergence speed, which aids the proposed ESSA algorithm to outclass the standard SSA and other recent algorithms. The fair analysis displays that ESSA delivers very promising results and outclass current methods. Next, frequency control of power systems is executed by designing a Combined Fuzzy PID (CFPID) controller with the projected ESSA method. Next, a Partially Distributed CFPID (PD-CFPID) controller is designed for a distributed power system (DPS). It is shown that the ESSA method outclasses the SSA method in engineering problems. It is also noted that the ESSA-based PD-CFPID scheme has become more operative in monitoring the frequency than similar structured centralized fuzzy PID (CFPID) as well as PID controller. Finally, the outcomes of the PD-CFPID controller are equated with CFPID and PID for various uncertain situations to validate the benefit of the proposed control approach.
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Fedorenko, Tatiana. "A system for managing the local economic development of communities". Scientific Bulletin of Mukachevo State University Series “Economics” 10, n. 4 (13 novembre 2023): 76–88. http://dx.doi.org/10.52566/msu-econ4.2023.76.
Abstract (sommario):
In today’s environment, it has become an important task to support and stimulate local economic development of communities to improve the living standards of the population and create sustainable and competitive community structures. The purpose of this study is to examine the system of management of local economic development of communities, which is becoming an increasingly important task in the context of social, economic, and political development of modern societies. The research has yielded the following results: using high-quality data from the publication Local economic development: Models, resources and financing tools, various models and approaches to managing local economic development of communities, including centralized and decentralized systems, as well as options for involving citizens in decision-making, were considered; using statistical sources of the Information and Analytical System for Monitoring Statistical and Administrative Indicators of Territorial Communities, Statistics Portal of Lithuania, Statistics Poland, a comparative analysis of local community development management systems in Ukraine, Poland, and Lithuania was carried out; the level of participation of citizens and stakeholders in decision-making processes and the development of local economic development strategies were analysed; the use of technology was assessed to improve the productivity of local economic development through ground research from the Centre for Innovation Development; the mechanisms of cooperation and coordination between different levels of government with the influence of factors were investigated and compared; territorial communities were analysed by region with regard to citizens’ appeals on the activities of local self-government bodies using statistical data from the website of the Government Contact Centre; recommendations and strategies for improving the system of local economic development management were developed. The study of the system of management of local economic development of communities is of great practical importance in modern conditions, where a favourable economic environment at the level of local communities is an important factor for improving the living standards of the population and creating sustainable and competitive community structures
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Pivovarov, A. A., E. A. Pivovarova e V. E. Kurganov. "About development of control levels of specific total alpha-activity in water samples for a number of sources of the centralized economic and drinking water supply in the Republic of Khakassia". Radiatsionnaya Gygiena = Radiation Hygiene 12, n. 2(св) (23 settembre 2019): 121–28. http://dx.doi.org/10.21514/1998-426x-2019-12-2s-121-128.
Abstract (sommario):
The aim of the work is to develop control levels of specific total alpha-activity of water samples for a number of sources of centralized drinking water supply in the Republic of Khakassia on the basis of the results of long-term laboratory studies. Materials and methods. The analysis is carried out on the basis of the results of laboratory studies of water sources of centralized drinking water supply of the population of the Republic of Khakassia, performed by accredited testing laboratories of institutions of the state sanitary and epidemiological service of the Republic for the period from 2001 to 2018, using alpha-beta radiometric, alpha-spectrometric methods with radiochemical preparation of counting samples, gamma-spectrometric method. The control levels of specific total alpha-activity of water samples from the sources of centralized drinking water supply in the Republic of Khakassia were established by the statistical maximum – the sum of the average value with a doubled standard deviation, with the volume of research more than 30, and the maximum value with the volume of research less than 30. Results. About half of the studied water samples from the sources of the centralized drinking water supply of the Republic of Khakassia, annually, are noted with exceeding the control level of specific total alpha-activity (0,2 Bq/kg). The values obtained in the studied samples vary up to 5,57 Bq/kg. During the observation period, samples of water exceeding the reference level of specific total alpha-activity (0.2 Bq/kg) were identified in settlements of the Altai, Askizsky, Beysky, Bogradsky, Ordzhonikidzevsky, Tashtypsky, Ust–Abakansky, Shira districts and the city of Sorsk, smt. Prigorsk (Chernogorsk). In previous studies, it was found that high levels of specific total alpha-activity in the country are mainly due to natural radionuclides uranium-238 (238U), uranium-234 (234U). In a number of settlements of the Republic, the sum of the ratio of specific activities of natural radionuclides to the corresponding levels of intervention exceeds 1,0. Average annual individual effective doses of internal exposure to natural radionuclides of drinking water, at or above 0,1 mSv/year (values in the range of 0,1-0,2 mSv/year), which does not require urgent radiation protection measures. At the same time, monitoring of indicators of radiation safety of water sources of water supply should be carried out in accordance with the established requirements. In this connection, in order to improve control, for the rapid assessment of the radiation situation and making timely decisions to ensure radiation safety of the population, the calculation of control levels of specific total alpha-activity was carried out. As a result of calculations, specific values of control levels for each of water source were obtained. The calculated values range from 0,2 to 2,6 Bq/kg. Conclusion. The control levels are “site standards” and are calculated for each of the source of water supply. Their excess will be considered as a signal of “negative change” of the radiation situation”, which may be associated with an increase of the specific activities of 234U, 238U, or the appearance of highly radiotoxic radionuclides: 226Ra, 210Po, 228Ra.
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Pritchett, Joshua, Aakash Desai, Bijan J. Borah, Zhuoer Xie, Antoine N. Saliba, Konstantinos Leventakos, Jordan Coffey et al. "Association of use of remote patient monitoring (RPM) with reduced hospitalizations in cancer patients with COVID-19." Journal of Clinical Oncology 39, n. 15_suppl (20 maggio 2021): 1503. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.1503.
Abstract (sommario):
1503 Background: Patients with cancer and COVID-19 are at risk for poor clinical outcomes. An established multi-site remote patient monitoring (RPM) service was rapidly adapted to support a novel, interdisciplinary COVID-19 program for outpatient management of patients at high-risk for severe illness. The goal of this study was to assess the impact of the RPM program on clinical outcomes and acute care utilization in cancer patients diagnosed with COVID-19. Methods: This is a cross-sectional analysis following a multi-site prospective observational study performed at Mayo Clinic Cancer Center (MCCC). All adult patients with active cancer – defined as currently receiving cancer-directed therapy or in recent remission on active surveillance – and PCR-confirmed SARS-CoV-2 infection between March 18 and July 31, 2020 were included. RPM was comprised of in-home technology to assess symptoms and physiologic data with centralized nurse and physician oversight. Results: During the study timeframe 224 cancer patients were diagnosed with COVID-19 at MCCC. Initial management included urgent hospitalization (within 48 hours of diagnosis) in 34 patients (15%). Of the remaining 190 patients (85%) initially managed in the outpatient setting, those who did not receive RPM were significantly more likely to experience hospitalization than those receiving RPM (OR 3.6, 95% CI 1.036 to 12.01, P = 0.044). Following balancing of patient characteristics by inverse propensity weighting, rates of hospital admission for RPM and non-RPM patients were 3.1% and 11% respectively, implying that RPM was associated with an 8% reduction in hospital admission rate (-0.077; 95% CI: -0.315 to -0.019, P = 0.009). Use of RPM was also associated with lower rates of prolonged hospitalization, ICU admission, and mortality, though these trends did not reach statistical significance. Conclusions: In the midst of a global pandemic associated with inpatient bed, ventilator, and PPE shortages, the RPM program provided an effective strategy for outpatient clinical management and was associated with decreased rates of hospitalization, ICU admission, and mortality in cancer patients with COVID-19. This care model enabled simultaneous opportunity to mitigate the increased risks of exposure, transmission, and resource utilization associated with conventional care.
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Назаркіна, В. М., М. М. Бабенко, А. С. Немченко e Т. М. Коба. "Regulatory and legal regulation and monitoring of procurement of medicines and medical devices under a state of martial law". Farmatsevtychnyi zhurnal, n. 2 (15 marzo 2024): 5–20. http://dx.doi.org/10.32352/0367-3057.2.24.01.
Abstract (sommario):
The national policy of public procurement in the health sector is based on its strategic importance in meeting urgent needs related to the safety of life and health of people. In the context of limited funding and growing needs of the healthcare system under martial law, it is extremely important to rationally use budget funds for the procurement of medicines with proven effectiveness and economic feasibility on the basis of HTA. The main problem of the medical procurement system is the imperfection of the regulatory framework and the lack of a clear and consistent position on the use of regulatory lists. The purpose of the study is to investigate the peculiarities of legal regulation and to monitor medical procurement under martial law. The research was based on the analysis of the legal framework, scientific and advisory publications, statistical and analytical data. According to the current legislation, medical procurement is carried out in the priority areas defined by the government, taking into account the estimated needs and allocated funding. One of the key problems is the formation and application of regulatory lists based on the results of the state HTA, and the regulation of procurement outside the National List is also relevant. An analysis of the structure and dynamics of centralized procurement for 2021–2023 was carried out. It was found that in terms of the number of ordered/purchased items and procurement amounts, adult oncology and cardiovascular diseases occupy leading positions. To ensure patients' access to high-cost innovative medicines, MEAs are used, and the current list contains 11 medicines that have passed the state HTA. Under martial law, decentralized medical procurement (at the regional level) is carried out using the procedure of requesting the price of proposals through Prozorro Market if the expected cost of procurement is more than UAH 50 thousand. The e-catalog includes 91 names of medical devices and 400 INN of medicinal products included in the National List, but not all of them are included in the State Formulary. Procurement under the price request procedure has proven to be effective by simplifying and shortening procedures, increasing competition and reducing prices. At the same time, the problem of harmonization of regulatory lists requires a systematic solution.
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Alekseev, Vadim B., Svetlana V. Kleyn, Svetlana A. Vekovshinina, Alena M. Andrishunas e Maxim V. Glukhikh. "Associated with the drinking water from centralized drinking water supply systems priority factors for deterioration of health of the population in the Russian Federation". HEALTH CARE OF THE RUSSIAN FEDERATION 66, n. 5 (17 ottobre 2022): 366–74. http://dx.doi.org/10.47470/0044-197x-2022-66-5-366-374.
Abstract (sommario):
Introduction. The population should be provided with qualitative drinking water that is also epidemiologically safe. This is the most vital task to solve in securing sanitary-epudemiological welfare of population in any country. The purpose of the study was to identify harmful factors that affect public health when people consume tap drinking water from centralized supply systems and to perform their hygienic assessment. Materials and methods. The study involved using data from statistical reports published by Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing (Rospotrebnadzor (Form No. 18)) and data provided by the Federal information fund of social-hygienic c monitoring collected in 2012-2021. Additional disease cases and deaths that were associated with water quality were calculated based on mathematical modelling of relationships within the “indicators of water quality - health disorders” system. Results. The study showed that in 2021 in the Russian Federation as a whole approximately 1.54 million disease cases were caused by poor quality of drinking water including violations of hygienic standards as by certain indicators. Health disorders were registered as per such nosology categories as “diseases of the digestive system”, “endocrine diseases”, “infectious and parasitic diseases” etc. Priority factors that cause additional diseases cases and deaths include chlorine and its organic derivatives, some metals such as iron, manganese, nickel, and boron. Microbiological agents also make a substantial contribution to medical and demographic losses. At the same time, a number of diseases cases associated with drinking water quality went down by more than 14% against 2012; a number of deaths decreased by 6.2%. Limitations of the study. Initial data are rather specific since they describe only the period from 2012 to 2021; all the established relationships between health and indicators of water quality have been determined based on regional data. Conclusion. Improvement of water quality requires implementing several priority activities. Water treatment faculties and pipelines should be modernized; a list of monitored indicators that describe water quality should be optimized (enlarged) considering incidence and mortality among population as per categories of nosologies associated with drinking water quality.
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Husni, M. Afif Rijal, Angga Ferdianto e Dimas Aulia Savitri. "Pelatihan Manajemen Rekam Medis dan Informasi Kesehatan Dasar FKTP di Puskesmas Tongguh Kabupaten Bangkalan Madura". Journal of Community Engagement in Health and Nursing 1, n. 2 (31 luglio 2023): 67–60. http://dx.doi.org/10.30643/jcehn.v1i2.304.
Abstract (sommario):
The medical record system includes a patient acceptance system, a medical record management syste and a statistical system. The patient reception area is the firs service gate in a health care facility. Some patients decide to seek treatment at a health care facility by considering a comfortable reception area and satisfactory staff. This Community Service activity method uses the Pre-Test, training, Post-Test and monitoring methods. Giving Pre-Test to trainees. Conduct medical record management training with an estimated time of 2 (two) days in week 5 with presentation of introductory material on medical record management. The UPT Puskesmas Tongguh still has 1 (one) officer with a medical record educational background, causing the officers to have a high workload, even though their work is assisted by other staff who come from non-meds record educational backgrounds and have never attended medical record training. The registration and enrollment system is not yet computerized, so it takes a long time for new patients to register. There are still many who do not record when borrowing in the expedition book so that their whereabouts are often not traced when needed. The storage system at the Tongguh Health Center is centralized by uniting outpatient and inpatient medical records in one folder while the alignment system is straight numerical filing (SNF). The Tongguh Health Center has not implemented retention of active to inactive medical records due to several obstacles such as a lack of human resources and a shortage of inactive medical record storage shelves.
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Valero, V., H. Roche, T. Pienkowski, J. Canon, Y. Zhao, W. Carney, J. Mackey, H. Taupin, M. Buyse e D. Slamon. "BCIRG 007: Serum HER2 levels in women with metastatic HER2-amplified breast cancer". Journal of Clinical Oncology 25, n. 18_suppl (20 giugno 2007): 1020. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.1020.
Abstract (sommario):
1020 Background: BCIRG 007 is a multicenter, phase 3 randomized trial comparing docetaxel and trastuzumab (TH) with docetaxel, platinum salt (cisplatin or carboplatin) and trastuzumab (TCH) as first line chemotherapy in women with metastatic breast cancer (MBC). Women enrolled in the study had to have primary breast tumors with HER2 amplification as determined by centralized FISH analysis. Methods: We determined the percentage of subjects with HER2 amplification who had elevated (>15ng/mL) baseline levels of serum HER2 prior to the initiation of trastuzumab-based therapies. Baseline was considered to be the last available determination within 21 days prior to first treatment. Results: The median baseline serum HER2 levels was 75.8 ng/mL (range=8–3,280 ng/mL) for all subjects (n=123), with no statistical difference between subjects randomized to receive TH (median=65.9 ng/mL, n=64) and those randomized to receive TCH (median=89.9 ng/mL, n=59). Overall, 89% of the 123 subjects with HER2-amplified primary tumors had serum HER2 levels >15 ng/mL at the time of metastatic disease (86% in TH vs 92% in TCH). Conclusions: There was no statistical impact of baseline serum HER2 levels on any important clinical event: response to treatment, clinical benefit (response or stable disease for more than 24 weeks), disease progression or death. Conversely, when serum HER2 was measured over time, subjects with higher levels had an elevated risk of experiencing progressive disease (p=.003), even after adjustment for extent of disease (1 or 2 vs 3 or more organs involved) and presence of visceral disease. These analyses suggest that monitoring serum HER2 levels over the course of disease may be a means for detecting progressive disease in women with HER2 amplified breast cancer. Given the long intervals between the serum HER2 measurement and progression (up to 9 months), caution is required in interpreting these results. No significant financial relationships to disclose.
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Pliuhin, Vladyslav, Vitaliy Teterev e Anatolii Lapko. "Smart Grid Technologies as a Concept of Innovative Energy Development: Initial Proposals for the Development of Ukraine". Lighting Engineering & Power Engineering 60, n. 2 (29 ottobre 2021): 47–65. http://dx.doi.org/10.33042/2079-424x.2021.60.2.02.
Abstract (sommario):
The formation of the concept of Smart Grid is associated with a number of issues, including theoretical and methodological. One of the main problems in forming such theory is to build its basis, the starting point for the development of which is the definition of Smart Grid as a systems of views concept on the future of power engineering, the principles of operation and technological basis of which undergoes significant changes compared to modern energy. The paper is aimed at reviewing and developing directions and approaches to the definition of Smart Grid in combination with machine learning mechanisms, highlighting their diverse and common nature to develop a holistic innovative energy development. In this paper, a study of the energy sector in Ukraine was conducted. Its efficiency and innovative development are considered. Problems with the implementation of Smart Grid technology, which arise when using alternative sources and monitoring and administration systems, were highlighted. The ways of mathematical formulation of the Smart Grid optimization problem are determined using the Data Science approach based on the machine learning system and neural networks. Big Data processing methods, Data Mining, statistical methods, artificial intelligence methods, and Machine Learning are analyzed. The design and development of databases and application software will be done using the Data Science method. Smart-technologies will take over the processes of control, accounting and diagnostics of assets, which will provide promising opportunities for self-recovery of the power system, as well as efficient operation of fixed assets. With the introduction of Smart Grid technologies for the Ukrainian power industry, significant fundamental changes will take place. This is the transition from centralized methods of generation and transmission of electricity to distributed networks with the ability to control energy production facilities and network topology at any point, including at the consumer level. Replacement of centralized demand forecasting according to the methodology of active consumer influence becomes an element and subject of the management system. A high-performance information and computing infrastructure will be built as the core of the energy system. This approach creates the preconditions for the widespread introduction of new devices that increase the maneuverability and controllability of the equipment. The creation of next-generation operational applications (SCADA/EMS/NMS) allows the use of innovative algorithms and methods of power system management, including its new active power elements.
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Pham Quang, Minh, e Krti Tallam. "Predicting Flood Hazards in the Vietnam Central Region: An Artificial Neural Network Approach". Sustainability 14, n. 19 (21 settembre 2022): 11861. http://dx.doi.org/10.3390/su141911861.
Abstract (sommario):
Flooding as a hazard has negatively impacted Vietnam’s agriculture, economy, and infrastructure with increasing intensity because of climate change. Flood hazards in Vietnam are difficult to combat, as Vietnam is densely populated with rivers and canals. While there are attempts to lessen the damage through hazard mitigation policies, such as early evacuation warnings, these attempts are made heavily reliant on short-term traditional statistical models and physical hydrology modeling, which provide suboptimal results. The current situation is caused by the fragmented approach from the Vietnamese government and exacerbates a need for more centralized and robust flood predictive systems. Local governments need to employ their own prediction models which often lack the capacity to draw key insights from limited flood occurrences. Given the robustness of machine learning, especially in low data settings, in this study, we attempt to introduce an artificial neural network model with the aim to create long-term forecast and compare it with other machine learning approaches. We trained the models using different variables evaluated under three characteristics: climatic, hydrological, and socio-economic. We found that our artificial neural network model performed substantially better both in performance metrics (91% accuracy) and relative to other models and can predict well flood hazards in the long term.
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Operchuk, N. I. "Analytical review of the results of monitoring epidemiological studies and infectious disease in the Kirovohrad region". Environment & Health, n. 3 (104) (settembre 2022): 48–56. http://dx.doi.org/10.32402/dovkil2022.03.048.
Abstract (sommario):
Objective: The aim of the work is to develop approaches to improving the information and analytical support for monitoring epidemiological studies and infectious diseases in the activities of public health institutions. Materials and methods: The studies were carried out on the basis of a retrospective review of long-term monitoring of epidemiological observations of infectious morbidity and indicators of microbiological and chemical pollution of environmental factors, performed by the state institution «Kirovohrad Regional Center for Disease Control and Prevention of the Ministry of Health of Ukraine». In this case, the following methods were used: dialectical - to determine the essence of information and analytical support for the activities of public health institutions; functional, comparative analysis - to analyze the activities of the state institution "Kirovohrad Regional Center for Disease Control and Prevention of the Ministry of Health of Ukraine"; model, integrated approaches - to develop a model of information and analytical support for the activities of public health institutions and measures for its implementation in practice; methods of statistical analysis - to determine the characteristics of the study of environmental objects and the dynamics of infectious diseases in the population. Results: According to monitoring observations of environmental objects in medical institutions, preschool and general educational institutions, social security institutions of the Kirovohrad region for 2020, which included data from 4196 studies, it was found that almost 15% of them do not meet the requirements of regulatory documents. At the same time, microbiological studies included 1207 samples and measurements, of which 117 samples (9.7%) were inappropriate, sanitary-chemical studies amounted to 2989 samples, of which 146 samples were inappropriate (4.9%) exceeding the permissible standards. The largest number of samples that do not comply with regulatory documents and pose a threat to human health were found in non-centralized water supply 77 samples. The analysis of the infectious morbidity of the population in the Kirovohrad region covered the period of 2018-2020, the dynamic review of which showed that, according to the criterion of general morbidity, the number of cases of infectious diseases is growing over time, while the incidence of infectious diseases in children tends to decrease. A number of shortcomings in accounting and data processing have been identified. Conclusions: The expediency of improving the methodological, software and technological support of the information and analytical direction of the functioning of the state institution "Kirovohrad Regional Center for Disease Control and Prevention of the Ministry of Health of Ukraine" is shown. This will improve the efficiency and quality of the implementation of monitoring studies, as well as the processing and analysis of the obtained data on the state of the environment and public health and the adoption of timely management decisions on its conservation.
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Dulău, Dorel, Lisa Craiut, Delia Mirela Tit, Camelia Buhas, Alexandra Georgiana Tarce e Diana Uivarosan. "Effects of Hospital Decentralization Processes on Patients’ Satisfaction: Evidence from Two Public Romanian Hospitals across Two Decades". Sustainability 14, n. 8 (17 aprile 2022): 4818. http://dx.doi.org/10.3390/su14084818.
Abstract (sommario):
Patient satisfaction represents an essential indicator in assessing healthcare quality, as it is an extensive source of information regarding the healthcare provider’s ability to meet patients’ expectations and is a key predictor of patients’ behavioral approaches. The purpose of this study is to evaluate the degree of satisfaction of patients who have been admitted for inpatient hospitalization in two public hospitals located in the North-West of Romania, during two different periods of administration/management of healthcare services, in the context of an ongoing decentralization process of public healthcare services (initiated in 2010). An exploratory study was conducted in the period of April–December 2021, based on a patient satisfaction survey, through which the quality of in-hospital services was evaluated at present and up until 2010, by the hospitalized patients in both periods. In total, 208 survey responses were validated and analyzed. The chi-square test and t-test were used for statistical processing. The results of the survey revealed that the percentage of patients that evaluated the inpatient experience as excellent was significantly higher during the period when hospitals were administered by local authorities than during the period of centralized administration (68.27% vs. 28.37%; p < 0.001), both in medical care as well as in hospital hotel services (71.63 vs. 29.81%), respectively (56.25 vs. 27.40; p < 0.001). The results obtained from this survey indicate that the decentralization of hospital units has had a positive effect on the quality of inpatient medical services and highlight the need for formulating and finalizing a policy aimed at developing and enhancing medical services.
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Mejía-Salazar, Jorge Ricardo, Kamilla Rodrigues Cruz, Elsa María Materón Vásques e Osvaldo Novais de Oliveira Jr. "Microfluidic Point-of-Care Devices: New Trends and Future Prospects for eHealth Diagnostics". Sensors 20, n. 7 (31 marzo 2020): 1951. http://dx.doi.org/10.3390/s20071951.
Abstract (sommario):
Point-of-care (PoC) diagnostics is promising for early detection of a number of diseases, including cancer, diabetes, and cardiovascular diseases, in addition to serving for monitoring health conditions. To be efficient and cost-effective, portable PoC devices are made with microfluidic technologies, with which laboratory analysis can be made with small-volume samples. Recent years have witnessed considerable progress in this area with “epidermal electronics”, including miniaturized wearable diagnosis devices. These wearable devices allow for continuous real-time transmission of biological data to the Internet for further processing and transformation into clinical knowledge. Other approaches include bluetooth and WiFi technology for data transmission from portable (non-wearable) diagnosis devices to cellphones or computers, and then to the Internet for communication with centralized healthcare structures. There are, however, considerable challenges to be faced before PoC devices become routine in the clinical practice. For instance, the implementation of this technology requires integration of detection components with other fluid regulatory elements at the microscale, where fluid-flow properties become increasingly controlled by viscous forces rather than inertial forces. Another challenge is to develop new materials for environmentally friendly, cheap, and portable microfluidic devices. In this review paper, we first revisit the progress made in the last few years and discuss trends and strategies for the fabrication of microfluidic devices. Then, we discuss the challenges in lab-on-a-chip biosensing devices, including colorimetric sensors coupled to smartphones, plasmonic sensors, and electronic tongues. The latter ones use statistical and big data analysis for proper classification. The increasing use of big data and artificial intelligence methods is then commented upon in the context of wearable and handled biosensing platforms for the Internet of things and futuristic healthcare systems.
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Wu, Ersilin, e Boi-yee Liao. "Correlation Fractal Dimension Analysis Mountainous Traditional Village Settlement Spatial Form –Case Study of Qiandongnan in Guizhou". Revista de Gestão Social e Ambiental 18, n. 4 (12 marzo 2024): e04741. http://dx.doi.org/10.24857/rgsa.v18n4-094.
Abstract (sommario):
Objective: A study carried out in the traditional villages of Qiandongnan in Guizhou province, located in China, to portray 409 traditional villages’ spatial distribution and fractal charicteristic, as well as its implications for the preservation of the group of traditional villages. Theoretical framework: From previous research, traditional village quantitative research on spatial area focuses on the statistics of mathematical models and spatial analyses of GIS, which indirectly reflect the complexity of the spatial patterns of traditional villages. Therefore, applying fractal theory to the spatial complexity of villages can provide a relatively objective and direct assessment for studying traditional villages with different formation backgrounds. Method: Data were collected in Google Earth map data and spatial data were obtained, which were synthesized and analyzed using spatial, statistical and mathematics analysis to verify the distribution factors and know about villages’ spatial fractal characteristics. Results and conclusion: The mountain settlements in Qiandongnan are concentrated in Leishan based on the Miao national group and “Liping-Congjiang-Rongjiang” based on the Dong national group. The q values of the explanatory power of each factor for the spatial distribution of traditional villages in the Qiandongnan area are, in descending order, intangible cultural heritage > GDP > distance from roads > height > the proportion of ethnic minorities > urbanization rate > average annual temperature > average annual precipitation > distance to rivers. Research implications: Villages contribute significantly to the enhancement of traditional Chinese culture, especially the preservation of historical buildings and distinctive local cultures. Furthermore, Knowing the factors of traditional village centralized contiguous protection mode and rural planning based on the policy of rural revitalization in China. Originality/value: Collected traditional villages’ distribution data from the official website and marked on the Google Earth map. Spatial analysis distribution of villages and emphasizes the importance of spatial correlation analysis in understanding the relationship between land use and rural population distribution.
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Preudhomme, Claude, Catherine Roche-Lestienne, Antoine Crinquette, Christophe Roumier, Virginie Eclache, Joëlle Guilhot, Francois Guilhot e François-Xavier Mahon. "Correlations between BCR-ABL Ratio and Cytogenetic Response at Months 12 of the Randomized French SPIRIT Study on Behalf the Fi-LMC Group." Blood 108, n. 11 (1 novembre 2006): 2150. http://dx.doi.org/10.1182/blood.v108.11.2150.2150.
Abstract (sommario):
Abstract In September 2003, the French CML study group (Fi-LMC) activated the four armed randomized SPIRIT trial comparing imatinib 400mg with imatinib 600mg, imatinib 400mg + ara-C and imatinib 400mg + pegylated interferon in newly diagnosed CML in chronic phase. The molecular monitoring was centralized and performed, according to the EAC protocol, in duplicate on the same BCR-ABL cDNA among two French laboratories (Bordeaux and Lille). Data were expressed as BCR-ABL/ABLx100 on the new internationally agreed scale (IS) using a conversion factor of 1.33 and 0.80 for Bordeaux and Lille respectively. A good correlation between the two laboratories was observed. During the first year of follow-up the quantification was performed each three months (M0 to M12). In May 2006, 297 of the 492 enrolled pts had a follow up of more than 12 months, and 263 pts were analysed at M12. Using the IS, the median values of the BCR-ABL/ABL normalized ratios were 90%, 6,4%, 0.68%, 0.32% and 0.16% at M0, M3, M6, M9, and M12 respectively. At M12, 15%, 29%, 27%, 17% and 12% of the pts presented a BCR-ABL/ABL ratio lower than 0.01%, 0.1% ,1%, 10%, and 100% respectively. Overall, 71% of the pts presented a ratio lower than 1%. Conventional cytogenetic data were available for 193 pts at M12: 156 pts (80%) were in complete cytogenetic response (CCR), 25 pts (13%) were in major cytogenetic response (MCR) and 12 pts (6.2%) were in minor or a lack of cytogenetic response. Among pts with a BCR-ABL transcript ratio lower than 1%, all except four were in CCR. The last 4 cases were in MCR associated with BCR-ABL ratios of: 0.96% for one pt, 0.08% and 0.12% for 2 pts (who further reached CCR at 6 and 18 months) and 0.128% for the last one. Percentages of Philadelphia positive metaphase (Ph+) were 4%, 6%, 5 % and 15% respectively. Among the 30 pts with a BCR-ABL ratio > 5%, none were in CCR and only 18 pts were in MCR. Among the 27 pts presenting a BCR-ABL ratio in the 1%–5% intervals, 20 pts were in CCR and 7 pts were in MCR (5 pts with Ph+ lower than 10% and two pts with 16% and 20% Ph+). In conclusion, our findings suggest that a ROC statistical test will be able to determine critical BCR-ABL/ABL ratios associated to CCR in our study. Nevertheless, at M12 the percentage of available data was superior using molecular than cytogenetic monitoring, suggesting that molecular monitoring expressed with the new international scale is probably sufficient fore more than 85 % of the pts treated by IM solely or in association.
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Jing, Xu, Yao Guanxin e Dai Panqian. "Quality Decision-Making Behavior of Bodies Participating in the Agri-Foods E-Supply Chain". Sustainability 12, n. 5 (2 marzo 2020): 1874. http://dx.doi.org/10.3390/su12051874.
Abstract (sommario):
The quality of agri-foods in e-supply chains confronts more threats than that in the traditional agri-food supply chain. However, most of the existing studies focusing on the quality problems of fresh agri-products are mainly cases studies and statistical analyses, and they do not take into account the farmers’ willingness to comply with safe agri-food supply procedures. To solve the supply quality problems of fresh agri-foods and help participators make a better choice, the decision-making behavior on the supply quality of agri-foods in the e-supply chain was deeply studied in this paper using game theory. Some factors related to the decision behavior of the supply chain were analyzed, including the supervision intension of the government, the rights protection consciousness of consumers, and the intensity of punishment for poor-quality agri-foods. These factors have an important influence on the farmers’ willingness to provide high-quality products and e-business’ probability of inspection. Compared with three different decision models of agri-food e-supply chains, the results show that the decentralized decision model is better than the centralized model from the view of quality protection. The behavior of members of the supply chain is as follows: the farmers’ willingness to supply high-quality agri-foods increases with the increase in the consumers’ consciousness of their rights and the government’s supervision intensity. The “experience deviation” phenomenon also occurs when a new e-business makes a decision about its quality inspection behavior in this e-supply chain where the quality information is traceable. As such, e-business enterprises should reduce their quality inspection behavior based on the increase in the government’s supervision intensity. This happens to be opposite to the traditional experience where quality information is not traceable. This study not only extends the research framework of the novel electronic supply chain, but also provides a certain reference for the subsequent research and e-business practices of fresh produce in developing countries.
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Charles, Muo, Jackson Ndolo e Sammy Odari. "Inventory management practices and performance of electoral systems in Kenya". International Journal of Social Science and Humanities Research (IJSSHR) ISSN 2959-7056 (o); 2959-7048 (p) 1, n. 1 (19 dicembre 2023): 811–26. http://dx.doi.org/10.61108/ijsshr.v1i1.64.
Abstract (sommario):
Effective inventory management plays a pivotal role in the overall performance and functionality of systems across various sectors. In the context of electoral systems, where precision, efficiency, and transparency are paramount, the management of inventory, including the planning, tracking, and control of resources, is of utmost importance. Therefore, the study sought to determine the role of inventory management practices on the performance of electoral systems in Kenya. The research design that was used in this study was a longitudinal research design. The population for this study consisted of 373 Commission Secretary/Chief Executive Officer (CS/CEO), Deputy Commission Secretary (DCS), Directors, Managers, County Election Managers, and Constituency Election Coordinators within 290 constituencies of Kenya's August 2017 election. A total of 373 respondents were used as the sample size for the study. Data was used as primary and secondary. While self-administered questionnaire and interview guide were used to collect primary data, the study reviewed the previous evaluation reports to seek the secondary data on General election performance. The data was collected and then analyzed by both descriptive and inferential statistical tools. Being that the study dealt with the relationship study, the study therefore used a regression model as a tool of analysis and the results that were generated were presented in the form of tables. The results of this study benefited policy makers, managers, administrators, citizens all whole, researchers, consultants, scholars, and trainers involved in Election Administration. This study tested the null hypotheses that inventory management practices had no significant role in the performance of electoral systems in Kenya. Pragmatism paradigm approach and mixed method research were adopted in this study. The questionnaire tested both validity and reliability. Quantitative and qualitative techniques were used to analyze the collected data with the assistance of Statistical Package for Social Sciences (SPSS) software version 25. Multiple regression and correlation analysis were carried out. The regression analysis results demonstrated a strong and significant role of inventory management practices on the performance of electoral systems. The R-squared values indicated that approximately 79% of the variation in electoral system performance was explained by inventory management practices. The adjusted R-squared value of 0.788 accounted for the number of predictors in the model. In conclusion, the study reveals that efficient inventory management practices significantly influence the performance of electoral systems in Kenya, emphasizing the need for standardized handling, storage, and transportation processes, the adoption of technology-driven monitoring systems, centralized inventory management, just-in-time approaches, regular cycle counting, and continuous improvement efforts. However, there remains unexplained variance in performance, warranting further investigation to identify additional influential factors. Additionally, future research should extend its focus to other countries in the East African region to comprehensively assess inventory management practices and their impact on electoral system performance
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Drelichman, Guillermo I., Nicolas Fernandez Escobar, Nora F. Basack, Maria S. Larroude, Gabriel Aguilar, Hugo Robledo, Leonardo J. Feldman et al. "New Prognostic Factors in the Assessment of Bone Complications in Gaucher Disease. Report from the Argentinian Group for Diagnostic and Treatment for Gaucher Disease". Blood 124, n. 21 (6 dicembre 2014): 4116. http://dx.doi.org/10.1182/blood.v124.21.4116.4116.
Abstract (sommario):
Abstract Objectives: the objectives of our study were to assess whether the current achievement of bone therapeutic goals (TG) correlate with the presence or absence of bone lesions (BL) and determine whether there are prognostic factors affecting response to enzyme replacement therapy (ERT) and the degree of bone involvement. Methods: 124 patients with Gaucher disease (GD) type 1 belonging to 45 centers in our country were studied. All studies were centralized in an imaging center and a central laboratory. Two points of evaluation were defined: 1) historical findings with data prior to diagnosis, diagnostic and data monitoring and 2) current findings with data obtained the day the following procedures were performed: total body resonance (TBR), volumetric resonance (VR), densitometry, complete blood count and chitotriosidase dosage. Five TG were evaluated according to the International Registration of Gaucher (ICGG). Results: with a median follow up of 15 years and a median treatment with ERT of 9.4, 105 patients (88%) achieved the five TG. Specifically bone TG were achieved by 90.3% of patients. However, this achievement was not correlated with the absence of BL as 87% of patients evaluated at day 0 showed different types of bone disease (BD) despite being in TRE. Reversible BL findings (infiltration and / or Erlenmeyer) and irreversible BL (infarcts and / or necrosis) increased from 71.8% at diagnosis versus 87% at study entry especially in relation to the appearance of acute BL (new) of osteonecrosis (24%). These discrepancies between the achievement of bone TG (90.3%), the presence of BD (87%) and the occurrence of acute BL (24%) show that the evaluation of the current bone TG is not accurate and it is necessary to evaluate more sensitive methods because it does not reflect the degree of bone involvement. We found four prognostic factors associated with the BD variable with statistical significance: ERT adherence, time between onset of symptoms and diagnosis, time between diagnosis and start of ERT and starting dose of ERT. Conclusions: these findings show that ERT "alone" can not maintain over time patients without chronic or acute BD or avoid the sequela. Several prognostic factors are associated with the likelihood that the patient is free of BD in the diagnosis and long-term monitoring. The findings at diagnosis of the following prognostic factors: late diagnosis (> 2 years) and a delay in treatment (> 2 years) were associated with a higher probability of irreversible BL. Findings in the monitoring of the following prognostic factors: good compliance to ERT, early initiation of ERT, early diagnosis and initial appropriate ERT dose at diagnosis according to risk level are associated with a greater likelihood of not presenting BD. According to this analysis we propose a new definition of bone TG and a new classification of prognostic groups (table 1). Table 1. New Prognostic Groups for BD in Gaucher Disease Prognostic Group Prognostic Factors Long - term consequences on Bone Group 1 (low risk of BD) ERT compliance > 90%Early diagnosis(< 2 years)Appropriate dose of ERT More likely not to present bone disease Group 2 (Intermediaterisk of BD) ERT compliance between > 80 and < 90%Delay in treatment(> 2 years) More likely to have reversible bone disease Group 3 (High risk of BD) ERT compliance between > 50 and < 80%More delay in treatment(> 2 years) More likely to have reversible and irreversible bone disease Group 4 (Very high Risk of BD) ERT compliance < 50%Low dose of ERT More likely to have reversible, irreversible and acute bone disease Disclosures Drelichman: Genzyme: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau. Fernandez Escobar:Genzyme: Research Funding, Speakers Bureau. Larroude:Genzyme: Honoraria. Aguilar:Genzyme: Honoraria.
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Bocchia, Monica, Anna Sicuranza, Paola Pacelli, Patrizia Pregno, Mario Annunziata, Federica Sorà, Elisabetta Abruzzese et al. "Prospective Monitoring of Peripheral Blood CD26+ Leukemia Stem Cells in Chronic Myeloid Leukemia Patients from Time of TKI Discontinuation". Blood 134, Supplement_1 (13 novembre 2019): 2919. http://dx.doi.org/10.1182/blood-2019-122814.
Abstract (sommario):
Background and rationale In chronic myeloid leukemia (CML) about half of patients (pts) achieving a deep and stable molecular response (MR) with tyrosine kinase inhibitors (TKIs) may discontinue TKI treatment without disease recurrence. As such, treatment free remission (TFR) has become an ambitious goal of treatment. Given the evidence that deepness and duration of molecular response are necessary but not sufficient requisites for a successful TFR, additional biological criteria to possibly identify more and better CML patients suitable for an efficacious discontinuation are today focus of research in CML. Leukemia stem cells (LSCs) are supposed to be the reservoir of disease. We first showed in a cross-sectional study including 112 pts in TFR for a median of 31 months (mos) that residual circulating CD34+/CD38-/CD26+ CML-specific LSCs were still detectable in the majority of CML pts despite stable and deep molecular response. This evidence suggested that the level of BCR-ABL transcript only may not reflect the actual residual CML LSCs burden and that there could be a "threshold" of LSCs predicting a successful TFR. Aims To further study the behavior of residual LSCs during TKI discontinuation we designed a prospective multicentered study (AIRC IG 20133 study) in which we monitored circulating CD26+ LSCs in CML pts from the time of TKI discontinuation until molecular relapse. Methods CML pts meeting the current molecular criteria for TKI withdrawal entered this multicenter study. At TKI stop (baseline) and at +1, +2, +3, +6, + 12 mos after discontinuation and at any time if molecular relapse, CML pts were evaluated for peripheral blood number of CD34+/CD38-/CD26+ LSCs by centralized flow-cytometry analysis and for BCR-ABL transcript level by standard (IS) quantitative RT-PCR assay. Results 49 consecutive CML pts were enrolled in the study so far. Pts characteristics at diagnosis, type of TKI, disease response and treatment duration before discontinuation are shown in Tab. 1. After a median time of 7 mos since TKI stop (range 1-24), 13/49 (26.5%) pts lost their molecular response and restarted TKI treatment. Median time to relapse after discontinuation was 4 mos (range 2-7). 36/49 (73.4%) pts are still in TFR after a median time of 7.5 mos (range 1-24). If considering a cut-off of 6 mos from discontinuation as the period with higher risk of relapse, 14/36 pts actually in TFR have discontinued treatment for ≤ 6 mos (range 1-6) while 22/36 pts are in TFR for a median of 10 mos (range 7-24). Regarding residual CML LSCs evaluation, at baseline 23/49 (46%) pts had still measurable circulating CD26+LSCs with a median number of 0.0204µ/L (range 0.0077-0.1197), while 26/49 (54%) had no detectable CD26+ LCSs. Considering the small number of molecular relapses no statistical difference in number of residual CD26+ LSCs at time of discontinuation was shown between pts losing vs maintaining TFR (13 pts median CD26+ LSC 0.0237/µ/L, range 0-0.1197 and 36 pts median CD26+ LSCs 0.0204/µ/L, range 0-0.1039, respectively). However, the number of pts with undetectable CD26+ LSCs at baseline was 6/13 (45%) and 20/36 (55%) in the two subgroups, respectively. Considering subsequent time points, the 13 relapsed pts showed a small yet progressive increase of residual CD26+ LSCs number until molecular relapse, while the 36 pts in TFR showed a fluctuation of CD26+ cells number. However, Kendall rank correlation coefficient, Mood test and bi-linear relation model of the whole cohort showed no correlation between BCR-ABL/ABLIS ratio and number of residual CD26+ LSCs either at baseline or at each time points after discontinuation, thus confirming our previous observations. Conclusions Yet very preliminary our results showed that CD26+ LSCs are detectable at time of TKI discontinuation and during TFR. Moreover, at least for the observation median time of the study (7.5 mos) the persistence of "fluctuating" values of residual CD26+ LSCs do not hamper the possibility to maintain a stable TFR. Due to the short follow up and the small number of molecular relapsed pts we could not find a threshold of CD26+ LSCs predictive of TFR loss. Our data may suggest other factors then LSCs "burden" to play an active role in controlling disease recurrence. Additional studies evaluating CD26+ LSCs ability to modulate the immune system through a variable expression of immune response inhibitory molecules and through their interactions with effectors cells are ongoing. Table Disclosures Bocchia: Novartis: Honoraria; Incyte: Honoraria; BMS: Honoraria. Pregno:Bristol Myers Squibb: Honoraria; Incyte: Consultancy, Honoraria; Novartis: Honoraria; Pfizer: Honoraria. Abruzzese:Incyte: Consultancy; Novartis: Consultancy; Pfizer: Consultancy; BMS: Consultancy. Crugnola:Novartis: Honoraria; Incyte: Honoraria. Iurlo:Pfizer: Honoraria; BMS: Honoraria; Incyte: Honoraria; Novartis: Honoraria. Galimberti:Roche: Speakers Bureau; Celgene: Speakers Bureau; Novartis: Speakers Bureau. Liberati:Bristol & Mayer: Honoraria; Takeda: Membership on an entity's Board of Directors or advisory committees; Celgene: Honoraria; Servier: Honoraria, Membership on an entity's Board of Directors or advisory committees; Incyte: Consultancy; Amgen: Membership on an entity's Board of Directors or advisory committees; AbbVie: Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Honoraria.
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Poudel, Shyam K., Xuefei Jia, Deborah Y. Park, Mailey Lynn Wilks, Vicki Pinkava, Meghan O'Brien, Barbara Tripp et al. "Clinical Outcomes of Isolated Distal Deep Vein Thrombosis Associated with Cancer: The Cleveland Clinic Experience". Blood 132, Supplement 1 (29 novembre 2018): 4809. http://dx.doi.org/10.1182/blood-2018-99-114897.
Abstract (sommario):
Abstract Introduction: Although a randomized trial showed no difference in progression of VTE in patients with isolated distal deep vein thrombosis (IDDVT) treated with anticoagulation vs. serial ultrasound monitoring, cancer patients were excluded from this study and remain a high risk population. Furthermore, studies to evaluate the long-term clinical outcomes of IDDVT in cancer patients have been limited. Here we report patient outcomes from our experience in treating cancer-associated IDDVT. Methods: We evaluated a prospective cohort of patients referred to our centralized cancer-associated thrombosis (CAT) clinic at the Cleveland Clinic Taussig Cancer Institute from 8/2014-5/2018. We evaluated clinical characteristics, anticoagulation prescription, venous thromboembolism (VTE) recurrence rate, major bleeding, hospital admission, and overall survival in patients diagnosed with IDDVT compared to those with proximal events. Statistical methods included t-tests, chi-squared tests, Cox model and competing risks model where appropriate. Multivariable analysis was performed to identify risk factors associated with overall survival and recurrence rate. Results: Data from 1100 patients were included in the analysis. After excluding upper extremity DVT, a total of 302 (27.5%) VTE events were diagnosed, 122 (40.4%) of which were IDDVT. Of patients diagnosed with IDDVT, 14 (11.7%) had a history of prior VTE and 48 (55.8%) had documented stage 4 cancer (see table 1). Low molecular weight heparin (LMWH) was the most commonly prescribed anticoagulant (50.8%) followed by rivaroxaban (35.2%). Seven patients (5.7%) did not receive anticoagulation due to contraindication. Proximal events were seen more often in males vs. females (110/180 (61.1%) vs. 70/180 (38.9%), p=0.027 and in those with stage 4 disease vs. stage 0-3 (95/120 (79.2%) vs. 25/120 (20.8%), p=0.001. Rate of VTE recurrence (see figure 2) in patients initially diagnosed with IDDVT was similar to the rate of VTE recurrence in proximal DVT or pulmonary embolism (PE), with 1-year incident rate of 12.7% and 8%, respectively, (HR 1.31, 95% CI, 0.54 - 3.15, p= 0.55). There was no difference in rate of major bleeding 6 months after the initial event between patients with IDDVT and proximal events, 4/17 (23.5%) vs. 7/30 (23.3%), respectively, p=1.0. There was no difference in subsequent hospital admission between those with IDDVT and proximal events 48/122 (39.3%) vs. 73/175 (41.7%), respectively, p=0.77. After multivariable analysis, there was no difference in overall survival between IDDVT vs. proximal events HR 1.43 (95% CI 0.88-2.32), p=0.15 (see figure 1). Overall survival was negatively impacted in patients with stage 4 disease, hematologic malignancy, male gender, and symptomatic VTE. Discussion: This study demonstrates that cancer patients with IDDVT have a similar rate of VTE recurrence, subsequent hospital admission, rate of major bleeding, and overall survival compared to those with proximal events. These findings, if validated, suggest that treatment of cancer-associated IDDVT should mirror treatment of proximal events. Disclosures Khorana: Janssen: Consultancy; Bayer: Consultancy; Pfizer: Consultancy; Sanofi: Consultancy.
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Thalji, Lisa, Craig A. Hill, Susan Mitchell, R. Suresh, Howard Speizer e Daniel Pratt. "The General Survey System Initiative at RTI International: An Integrated System for the Collection and Management of Survey Data". Journal of Official Statistics 29, n. 1 (1 marzo 2013): 29–48. http://dx.doi.org/10.2478/jos-2013-0003.
Abstract (sommario):
Abstract There is a risk of introducing survey error at every stage of any study involving a survey: design, data collection, processing, and analysis. Effectively managing the survey sample from the time of sample selection through the survey lifecycle is essential to producing highquality data on schedule and within budget. Managing the survey lifecycle using software systems that are not fully integrated can result in error and cost inefficiencies. The development of an integrated data collection and management system that supports monitoring of survey error has the potential to reduce errors and improve operational efficiencies. This system, referred to as Nirvana, uses a standardized database, protocol, and terminology. It integrates case status and history information across modes of data collection and tracing as well as sample and contact information. Nirvana also centralizes questionnaire development, quality monitoring, and support for real-time survey management decisions.
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Guo, Dayong, e Qing Hu. "Design of multi-indicator integrated testing system for tobacco intelligent silk production line". Journal of Intelligent & Fuzzy Systems 42, n. 3 (2 febbraio 2022): 2615–27. http://dx.doi.org/10.3233/jifs-211936.
Abstract (sommario):
Aiming at the problems of low precision, slow data transmission speed and long response time of silk quality and temperature control in tobacco intelligent production line, a multi-index testing system is designed. According to the characteristics of PROFIBUS fieldbus technology, combined with PROFIBUS transmission technology, a factory level information network is formed with PROFIBUS-DP as the exchange mode. Based on the PROFIBUS technology, the dual redundancy structure of control ring network and management information ring network is adopted, and the whole network architecture is constructed by logic layering. From the point of view of building enterprise MES system, it locates real-time production monitoring, production task receiving and production line related data collection, integrates equipment control layer, centralized monitoring layer and production management layer, and designs system function structure. The functional structure of the system, and the establishment of a number of data tables, to achieve a tobacco intelligent production line silk quality detection system design. Experimental results show that this method can effectively speed up the data transmission speed and shorten the system response time.
50
Moore, D. C., e I. M. Davies. "Monitoring the effects of the disposal at sea of Lothian Region sewage sludge". Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences 93, n. 3-4 (1987): 467–77. http://dx.doi.org/10.1017/s0269727000006886.
Abstract (sommario):
SynopsisUntil the late 1970s Edinburgh and the surrounding areas employed a series of relatively short sea outfalls to dispose of sewage to tidal waters. A centralised sewage treatment facility was provided in 1977, with disposal of liquid effluent by long sea outfall. The residual wet solids are dumped at two sites in the North Sea off the Firth of Forth. The sites, one near Bell Rock (56 25N 02 10W) and one ten miles north of St Abb's Head (56 04·5N 02 07·25W) are used on a rotational basis. The macrofauna at both sites shows a normal polychaete-dominated community exhibiting the normal low number/high diversity characteristics of many unimpacted communities in the North Sea. In general, seasonal differences in mean concentrations of lead, copper and zinc in sediments were small and within the limits of statistical variation. The concentrations of mercury and cadmium were mainly low and close to the detection limits of the analytical methods employed. The monitoring data from Bell Rock and St Abb's Head demonstrate that the dumping operation has had little effect on the benthic environment and that the macrobenthos showed no signs of stress due to the addition of sewage sludge.