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1

Sriperumbuduri, Sriram, Mohan Biyani, Pierre Antoine Brown e Brendan B. McCormick. "Retrospective study of patients on hybrid dialysis: Single-center data from North America". Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 40, n. 2 (17 gennaio 2020): 224–26. http://dx.doi.org/10.1177/0896860819887284.

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Abstract (sommario):
Hybrid dialysis involves combining peritoneal and hemodialysis (HD) in patients with end-stage renal disease. Its reported use is quite limited outside of Japan. We present a retrospective review of 18 patients at our center that received this therapy and describe their ultimate disposition. We observed that 39% of the population on hybrid dialysis ultimately transitioned to full in center HD, 28% continue until death, and 33% either transition to home HD or received a transplant. In our center, hybrid dialysis was successful as a bridging therapy or in balancing continuation of dialysis with quality of life among those with a limited prognosis.
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2

Dosil-Díaz, Carlos, David Facal e Romina Mouriz-Corbelle. "Behavioral Interventions in Long-Term Care Facilities during the COVID-19 Pandemic: A Case Study". Geriatrics 7, n. 1 (21 dicembre 2021): 1. http://dx.doi.org/10.3390/geriatrics7010001.

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Abstract (sommario):
During the COVID-19 pandemic, long-term care (LTC) centers have adopted a series of measures that have affected the physical and cognitive health of patients. The routines of the patients, as well as the interventions of professionals, have been altered. In the case presented here, our aim was to explain the effect that the strong confinement due to the spread of the first COVID-19 wave in Spain had on a 75-year-old resident in an LTC center, with cognitive and behavioral symptomatology compatible with a diagnosis of mixed dementia, as well as the measures that the center adopted to manage the lockdown situation in the best possible way, including personalized attention protocols and a video call program. Different nosological hypotheses are also raised using a semiological analysis, including the analysis of the initial and continuation diagnostic protocols, as well as the therapeutic options.
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3

Komatsu, Masamichi, Hiroshi Yamamoto, Takashi Ichiyama, Satoshi Kawakami, Takeshi Uehara, Yumi Yoshikawa, Yoshiaki Kitaguchi, Atsuhito Ushiki, Masanori Yasuo e Masayuki Hanaoka. "Tolerability of nintedanib in the elderly with idiopathic pulmonary fibrosis: A single-center retrospective study". PLOS ONE 17, n. 2 (3 febbraio 2022): e0262795. http://dx.doi.org/10.1371/journal.pone.0262795.

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Abstract (sommario):
Idiopathic pulmonary fibrosis (IPF), a fibrosing interstitial lung disease, predominantly affects the elderly and is associated with a high mortality risk. Nintedanib, a tyrosine kinase inhibitor, significantly reduces IPF progression. However, data on the tolerability and efficacy of nintedanib in the elderly with IPF are limited. Therefore, this study aimed to examine the tolerability and efficacy of nintedanib in the elderly with IPF in a real-world setting. Medical records of 19 elderly IPF patients (≥ 75 years) and 46 non-elderly IPF patients (< 75 years) newly administered nintedanib were retrospectively analyzed. We compared the forced vital capacity (FVC) level, incidence and severity of adverse events, and continuation rates of nintedanib between the two groups. FVC and percent predicted diffusing capacity of the lung for carbon monoxide (DLco) were lower in the elderly IPF group at baseline. Although the elderly IPF patients had a significantly higher incidence of adverse events, such as diarrhea, nausea, and elevation of hepatic enzymes, the rate of discontinuation of nintedanib owing to adverse events was not different between the groups. The continuation rates of nintedanib treatment at 6 months and 1 year in the elderly IPF group were equivalent. Furthermore, there was a similar trend in the reduction of the annual FVC decline after nintedanib initiation between the groups. Our study demonstrated that nintedanib was tolerable in both the IPF patient groups in a real-world setting. Proper management of adverse events in the elderly with IPF would lead to a better clinical outcome.
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4

Yamamiya, Akira, Katsuya Kitamura, Yu Ishii, Yuta Mitsui e Hitoshi Yoshida. "Safety of endoscopic sphincterotomy in patients undergoing antithrombotic treatment: a retrospective study". Therapeutic Advances in Gastrointestinal Endoscopy 12 (gennaio 2019): 263177451984632. http://dx.doi.org/10.1177/2631774519846327.

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Abstract (sommario):
Background: This study investigated the safety of endoscopic sphincterotomy in patients undergoing antithrombotic treatment. Methods: From January 2014 to December 2016, a single-center retrospective study was conducted. Of the 80 patients with naïve papilla receiving antithrombotic treatment who underwent endoscopic sphincterotomy, 76 patients were retrospectively analyzed. We divided the participants into two groups as follows: 45 patients who discontinued antithrombotic treatment (discontinuation group) and 31 patients who continued antithrombotic treatment (continuation group). We evaluated the safety of endoscopic sphincterotomy in patients with naïve papilla who received antithrombotic treatment. Results: The percentage of patients requiring emergency endoscopic retrograde cholangiopancreatography in the continuation group was significantly higher than that in the discontinuation group (55% vs 11%; p = 0.001). The incidence of adverse events did not differ significantly between the two groups. Neither bleeding nor perforation occurred in either group. The length of hospital stay did not differ significantly between the two groups. Conclusions: Endoscopic sphincterotomy in patients undergoing antithrombotic treatment may be safe if the guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment are followed.
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5

Fuengfoo, Adidsuda, Kim Sakulnum e Sumitra Owjinda. "Effectiveness of 36 hospital learning centers in Thailand: continuation of child patient education, parent attitudes toward child’s illness and service satisfaction". F1000Research 9 (13 aprile 2022): 1446. http://dx.doi.org/10.12688/f1000research.26599.2.

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Abstract (sommario):
Background: This study aimed to determine the effectiveness of 36 hospital learning centers for the continued education of sick children using electronic distance learning television (eDLTV), parents’ attitudes toward their child’s illnesses and education, and service satisfaction of the centers. Methods: The sample included 4,430 children aged 4-18 years old with common illnesses, chronic illnesses and developmental disorders, as well as 4,430 parents who had taken care of the child for at least 6 months. The methods included attitude surveys, which were analyzed using chi-square tests and t-tests. Results: The factors associated with education continuation of the children were illness types (parents were less worried about children with common illness and more concerned about education of children with chronic diseases and children with disabilities), distance from home to school, transportation type, parents’ education level, marital status, and family income. About 99.8% of patients with common illnesses continued their education, followed by 99.3% of disabled children, and 95.9% of chronic patients. Satisfaction score towards the services at the learning centers were high (mean scores: 4.28 and 4.43 respectively, out of 5 = strongly satisfied). Conclusion: After completing an education program through eDLTV at a center, a total of 97.7% of children continued their education and were highly satisfied with the service at the center. Parents had positive attitudes towards their child’s illnesses and education.
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6

Fuengfoo, Adidsuda, Kim Sakulnum e Sumitra Owjinda. "Effectiveness of 36 hospital learning centers in Thailand: continuation of child patient education, parent attitudes toward child’s illness and service satisfaction". F1000Research 9 (11 dicembre 2020): 1446. http://dx.doi.org/10.12688/f1000research.26599.1.

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Abstract (sommario):
Background: This study aimed to determine the effectiveness of 36 hospital learning centers for the continued education of sick children using electronic distance learning television (eDLTV), parents’ attitudes toward their child’s illnesses and education, and service satisfaction of the centers. Methods: The sample included 4,430 children aged 4-18 years old with common illnesses, chronic illnesses and developmental disorders, as well as 4,430 parents who had taken care of the child for at least 6 months. The methods included attitude surveys, which were analyzed using chi-square tests and t-tests. Results: The factors associated with education continuation of the children were illness types (parents were less worried about children with common illness and more concerned about education of children with chronic diseases and children with disabilities), distance from home to school, transportation type, parents’ education level, marital status, and family income. About 99.8% of patients with common illnesses continued their education, followed by 99.3% of disabled children, and 95.9% of chronic patients. Satisfaction score towards the services at the learning centers were high (mean scores: 4.28 and 4.43 respectively, out of 5 = strongly satisfied). Conclusion: After completing an education program through eDLTV at a center, a total of 97.7% of children continued their education and were highly satisfied with the service at the center. Parents had positive attitudes towards their child’s illnesses and education.
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7

Mukh, Yasmeen Nzam Abu, e Safia Tarteer. "THE ROLE OF ICT CENTERS IN THE PALESTINIAN UNIVERSITIES DURING THE COVID-19 PANDEMIC". Journal of Southwest Jiaotong University 56, n. 4 (30 agosto 2021): 457–69. http://dx.doi.org/10.35741/issn.0258-2724.56.4.41.

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Abstract (sommario):
Recently published work has revealed that the dire consequences of Covid-19 have affected different life sectors worldwide, especially education. Supporting the ICT centers will enforce the infrastructure; this will lead to strong remote learning during crises. This study encouraged the ICT center to practice the professors and support both teachers and students in using digital tools such as mobile in their learning. For this study, it was interesting to identify the technical support types provided by the ICT centers in selected Palestinian Universities for lecturers. Therefore, we analyzed the possibility of improving ICT centers' quality and investigated whether we can enrich the outcomes of ICT centers from the lecturers' perspective. For data collection, online interviews were conducted with 8 participants from different Palestinian Universities. We seek an overarching framework according to the grounded theory. Slightly superior results are achieved with our framework. We found that the types of technical services from the ICT center at Palestinian universities were graded in time according to the motives of the need. The paper concludes by arguing that universities should hone lecturers' ICT app skills. These findings provide a potential mechanism for lecturers to enhance their ability to employ online tools appropriately in teaching to ensure the smooth continuation of the learning process in Palestine.
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8

Mukh, Yasmeen Nzam Abu, e Safia Tarteer. "THE ROLE OF ICT CENTERS IN THE PALESTINIAN UNIVERSITIES DURING THE COVID-19 PANDEMIC". Journal of Southwest Jiaotong University 56, n. 4 (30 agosto 2021): 457–69. http://dx.doi.org/10.35741/issn.0258-2724.56.4.41.

Testo completo
Abstract (sommario):
Recently published work has revealed that the dire consequences of Covid-19 have affected different life sectors worldwide, especially education. Supporting the ICT centers will enforce the infrastructure; this will lead to strong remote learning during crises. This study encouraged the ICT center to practice the professors and support both teachers and students in using digital tools such as mobile in their learning. For this study, it was interesting to identify the technical support types provided by the ICT centers in selected Palestinian Universities for lecturers. Therefore, we analyzed the possibility of improving ICT centers' quality and investigated whether we can enrich the outcomes of ICT centers from the lecturers' perspective. For data collection, online interviews were conducted with 8 participants from different Palestinian Universities. We seek an overarching framework according to the grounded theory. Slightly superior results are achieved with our framework. We found that the types of technical services from the ICT center at Palestinian universities were graded in time according to the motives of the need. The paper concludes by arguing that universities should hone lecturers' ICT app skills. These findings provide a potential mechanism for lecturers to enhance their ability to employ online tools appropriately in teaching to ensure the smooth continuation of the learning process in Palestine.
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9

Servais, Abigail, John Schoen, Trevor C. Van Schooneveld, Erica J. Stohs e Scott Bergman. "1023. Isavuconazonium Use at an Academic Transplant Center". Open Forum Infectious Diseases 6, Supplement_2 (ottobre 2019): S360. http://dx.doi.org/10.1093/ofid/ofz360.887.

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Abstract (sommario):
Abstract Background Isavuconazonium is an appealing anti-fungal due to its broad spectrum of activity, predictable pharmacokinetics, oral bioavailability, and lack of QTc prolongation, but real-world experience with it is limited. At our academic medical center, isavuconazonium is restricted to the infectious diseases (ID) service for treatment of invasive fungal infections, including endemic mycoses due to high prevalence, and is recommended for patients intolerant of first-line agents. The purpose of this study was to describe isavuconazonium use at our institution and assess adherence to its formulary guidelines. Methods Inpatients with an order for isavuconazonium between June 2016 and November 2018 were analyzed via retrospective chart review. Prescribing team, indication, and rationale for use were evaluated. Results There were 97 inpatient encounters with an isavuconazonium order among 57 patients. Of those, 30 were solid-organ transplants and 9 had bone marrow transplants. Indications for isavuconazonium were: histoplasmosis 25%, high-risk fungal prophylaxis 21%, invasive aspergillosis 9%, candidiasis 2%, and other 44% (Table 1). Preceding anti-fungal therapy included: voriconazole 49%, posaconazole 12%, fluconazole 9%, micafungin 7%, amphotericin B 5%, itraconazole 4%, and none 35%. The rationale for the use of isavuconazonium is described in Table 2. ID consultation occurred in 79% of patients. Those without a consult had an indication of prophylaxis or were continuation of therapy started outpatient or at an outside hospital (OSH). Conclusion Histoplasmosis was the most common infection treated with isavuconazonium, despite limited data for that indication. Further investigation of the clinical course for these patients is warranted. Reasons for use most commonly centered on concern for QTc prolongation, clinical failure, and drug interactions. Over one-third of patients received no anti-fungal therapy prior to initiation. Adherence to required ID consultation was high. Patients on isavuconazonium for prophylaxis or as continuation therapy without a consult may still benefit from ID review to assess the appropriateness of therapy. Disclosures All authors: No reported disclosures.
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10

Xiong, X., K. L. Deng e T. Q. Wu. "Comparing the spatial domain and frequency domain algorithms for upward continuation of marine magnetic anomaly". Journal of Physics: Conference Series 2486, n. 1 (1 maggio 2023): 012065. http://dx.doi.org/10.1088/1742-6596/2486/1/012065.

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Abstract (sommario):
Abstract Space potential field continuation is a method frequently used for the spatial transformation of magnetic anomaly in the sea area, and is the key technology for constructing three-dimensional marine magnetic field model and the application of marine magnetic survey data. In this study, we analyze the principle of upward continuation of potential field from plane to plane, demonstrate the spatial domain algorithm and frequency domain algorithm, and propose the standards for evaluating the accuracy of the two algorithms. Using the theoretical data of the multi-dipole sphere model, we employ the two algorithms to continue the magnetic anomaly of the observation plane at the height 0 m to 100 m, 200 m, and 300 m, for noisy and noise-free conditions. The results show that the continuation error of the two methods is extremely small at the plane center, but large on the edge; the spatial domain algorithm has obviously better accuracy than the frequency domain algorithm, so it should be preferentially selected in high-precision applications, such as magnetic anomaly detection in the sea area.
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11

Mikhnin, A. E., P. S. Kalinin, E. V. Levchenko e Van Ting. "Experimental Study of CT-densitometry on Physical Phantoms". Medical Visualization, n. 2 (16 luglio 2019): 36–43. http://dx.doi.org/10.24835/1607-0763-2019-2-36-43.

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Abstract (sommario):
Objective: to assess the accuracy of CT densitometry as a method for measuring the X-ray density of an object, as well as factors affecting the measurement results.Material and methods. X-ray density indicators were measured in various zones of phantoms containing drinking water with a volume of 0.5, 1.0, 1.5, and 2.0 l, as well as 5 identical vials with a capacity of 0.25 l with iopromide solutions with a concentration of 0, 5.2, 7.6, 10 and 20 ml/l. For each phantom, from 5 to 10 scans were made, followed by measuring the X-ray density of the contents in the central zone closest to the CT system center of rotation, and two zones located to the periphery from the center of rotation.Results. As a result of analyzing the values of measuring X-ray density in various parts of water-containing phantoms, an increase in the values of X-ray density near the center of rotation of the system and in the upper sections of the phantom with an increase in the volume of phantom was revealed. In the lower peripheral zone in 1.5 and 2.0 liter phantoms, the X-ray density was unchanged. The overestimation of the X-ray density values of the CT images of phantoms with small and large concentrations of iopromide during co-scanning compared with separate scanning was determined.Conclusion. CT densitometry is a highly sensitive method for measuring the X-ray density of image elements, however, the X-ray density of neighboring structures and the location of this zone relative to the center of rotation of the CT system affect the CT densitometry results. During jointly scanning phantoms of various densities, their mutual influence and the appearance of specific artifacts in the form of dark stripes on the lines of continuation of horizontal levels and “pulling up” the edges of these horizontal contrast levels to the center of rotation of the system were noted.
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Florio, Giovanni, e Maurizio Fedi. "Depth estimation from downward continuation: An entropy-based approach to normalized full gradient". GEOPHYSICS 83, n. 3 (1 maggio 2018): J33—J42. http://dx.doi.org/10.1190/geo2016-0681.1.

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Abstract (sommario):
The normalized full gradient is based on the noticeable stability of the modulus of the analytic signal of downward potential fields. We have developed a new approach to the study of the normalized full gradient, based on assessing the entropy of the normalized modulus of the analytic signal at each level of continuation. The increased disorder of progressively downward continued fields implies an increase of the computed entropy. However, a local decrease of the entropy is expected at the source level, where the field gets singular, as entropy decreases when the information is concentrated. Thus, our method is based on a simple search for a minimum of the computed entropy versus depth curve, and the estimated depth will be that at which the minimum is attained. The method is sensitive to interference and other types of noise, and specific strategies to deal with these limitations are defined and tested on synthetic data. The depth estimate is obtained without the assumption of a specific source shape. The depth could correspond to the top or center in case of a simple, one-point source, or it may be related to an intermediate depth between the source top and its center in case of a finite, general source. We applied this method to real magnetic data from an unexploded ordnance survey, and it could verify a rather accurate depth-to-source estimate when compared with excavation results.
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Martinez, A., M. De Carolis, B. Marandyuk, S. Tremblay, G. Lodygensky, A. Birca e E. Pinchefsky. "P.090 Symptomatic neonatal seizure treatment duration and seizure recurrence: a retrospective single center study". Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 49, s1 (giugno 2022): S31—S32. http://dx.doi.org/10.1017/cjn.2022.186.

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Abstract (sommario):
Background: While seizures have adverse neurological effects, the prescribed antiseizure medications (ASMs) may also have a negative impact on neonatal brains and contribute to detrimental neurodevelopmental outcomes. The objectives were to evaluate: 1) the impact of implementing a neonatal seizure treatment protocol in 2016; 2) the influence of ASM duration and other clinical factors on seizure recurrence and epilepsy onset. Methods: Retrospective chart review of 139 term newborns born between 2013 and March 2021 admitted at Sainte-Justine University Center Hospital with acute symptomatic seizures. Associations were assessed using Student T-test and Fisher exact test. Results: We did not observe significant change in the number of ASMs prescribed for acute seizure control (33% required 33 ASMs before vs 22% after 2016) nor significant change in frequency of prescription of ASM at discharge over time. ASM continuation at discharge was not associated with seizure recurrence (p=0.14, OR 2.14, 95%CI 0.78-5.86) or epilepsy (p=0.78, OR 1.32, 95% CI 0.45-3.90). Epilepsy occurred in 15 (12%) of children between 15 days to 72 months of age. Conclusions: No association was found between ASM maintenance at discharge following acute symptomatic neonatal seizures and the occurrence of epilepsy. Discontinuation of ASMs should be considered prior to discharge.
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Kornstein, Susan G. "Beyond Remission: Rationale and Design of the Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) Study". CNS Spectrums 11, S15 (dicembre 2006): 28–34. http://dx.doi.org/10.1017/s1092852900015236.

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AbstractRecurrent major depressive disorder (MDD) is a common and disabling illness, but few studies have addressed long-term antidepressant treatment of recurrent MDD (ie, beyond 1 year of maintenance therapy) or compared the efficacy and safety of different antidepressant classes in this population. This article describes the rationale and design of a unique multi-phase trial in patients with recurrent MDD. The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) study is a large double-blind, randomized, multi-center trial designed to assess the long-term efficacy of venlafaxine extended release (ER) in the prevention of depressive recurrence. Approximately 1,100 adult outpatients with MDD and a history of ≥3 lifetime episodes (with at least two occurring in the past 5 years) were randomized to 10 weeks of acute-phase treatment with either venlafaxine ER 75–300 mg/day or fluoxetine 20–60 mg/day, followed by 6 months of continuation-phase treatment for patients experiencing a satisfactory therapeutic response or remission during the acute phase. Responders and remitters to continuation phase treatment were then entered into a 2-year maintenance phase study, in which those receiving venlafaxine ER were re-randomized to either venlafaxine ER or placebo at the start of two 12-month maintenance periods. Those taking fluoxetine during the acute and continuation phases continued to receive double-blind treatment with fluoxetine. This study will address several unanswered questions about the long-term treatment of recurrent MDD, such as whether extended maintenance treatment (ie, up to 2 years) lessens the risk for developing future depressive episodes; whether fluoxetine and venlafaxine ER are effective for both short- and long-term treatment of MDD; whether rates of tachyphylaxis differ between anti- depressant classes; and whether the likelihood of depressive recurrence differs according to the time point when treatment is discontinued.
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15

Wohlt, Paul D., Lizbeth A. Hansen e Jeffrey T. Fish. "Inappropriate Continuation of Stress Ulcer Prophylactic Therapy After Discharge". Annals of Pharmacotherapy 41, n. 10 (ottobre 2007): 1611–16. http://dx.doi.org/10.1345/aph.1k227.

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Abstract (sommario):
Background: Medications for stress ulcer prophylaxis are appropriately started in critically ill patients with risks for developing stress ulcers. It is unknown whether these drugs are discontinued once the risk factors are removed. Objective: TO assess the duration of stress ulcer prophylactic therapy in critically ill patients. Methods: A retrospective chart review was conducted at a multidisciplinary, 24 bed medical/surgical intensive care unit (ICU) of a university-affiliated tertiary referral medical center. Three hundred ninety-four patients fulfilled eligibility criteria during the study period of July 1, 2005, through September 30, 2005. Patients were considered to be appropriately discharged from the hospital on gastric acid suppressants it they met any of the following criteria: continued mechanical ventilation, gastroesophageal reflux disease, peplic ulcer disease, history of gastrointestinal ulceration or bleeding within the past year, prescribed medications used for stress ulcer prophylaxis prior to admission, gastrointestinal bleed during hospitalization, or prescriber indication of reason to continue therapy. Results: Three hundred fifty-seven patients received stress ulcer prophylaxis during their ICU stay. Of these, 80% continued on gastric acid suppressants on transfer from the ICU, with 60% of the therapy being inappropriate. The percentage of critically ill patients discharged from the hospital with inappropriate prescription of gastric acid suppressants was 24.4%. Based on the average wholesale cost, the total cost for unnecessary gastric acid suppressant therapy within the follow-up period was $13,973. Conclusions: Gastric acid suppressant medications initially prescribed for stress ulcer prophylaxis are frequently prescribed inappropriately on discharge for patients who were initially admitted to the medical/surgical ICU.
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Kobayashi, Ami, Hironori Takahashi, Shigeki Matsubara, Yosuke Baba, Shiho Nagayama, Manabu Ogoyama, Kenji Horie et al. "Prognosis and Prognostic Factors of Patients with Emergent Cerclage: A Japanese Single-Center Study". Obstetrics and Gynecology International 2021 (26 dicembre 2021): 1–7. http://dx.doi.org/10.1155/2021/4351783.

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Abstract (sommario):
Objectives. The aims of this study were to clarify the following: (1) how often does prolonged pregnancy ≥34 weeks occur in patients with emergent cerclage without progesterone and (2) the risk factors preventing such pregnancy continuation. Materials and Methods. This retrospective observational study was performed using medical records of patients for whom emergent cerclage had been performed between April 2006 and December 2018 in our institute. Results. Emergent cerclage was performed in 123 patients (median age: 34, interquartile range: 31–36). Primiparous patients numbered 44 (36%). A history of spontaneous preterm birth (SPTB) was present in 30 (24%). The median presurgical cervical length (CL) was 16 (8–21) mm at surgery. Of the 123, 20 (16%) were delivered at 33 + 6 weeks or less (<34 weeks). We conducted logistic regression analysis of the risk factors of SPTBs <34 weeks after cerclage. Three risk factors were identified that increased the risk of SPTB <34 weeks: presurgical CL 0 mm (odds ratio (OR): 5.30; 95% confidence interval (CI): 1.58–17.7), a history of SPTB (OR: 4.65; 95% CI: 1.38–15.7), and the presence of sludge (OR: 4.14; 95% CI: 1.20–14.3). Conclusion. Three risk factors predicted SPTB <34 weeks after emergency cerclage without progesterone administration: unmeasurable CL (CL 0 mm), a history of SPTB, and the presence of sludge on ultrasound. SPTB <34 weeks occurred after emergency cerclage in 16% of patients, being comparable with the recent data with progesterone.
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Dai, Yunxian, Yiping Lin e Huitao Zhao. "Hopf Bifurcation and Global Periodic Solutions in a Predator-Prey System with Michaelis-Menten Type Functional Response and Two Delays". Abstract and Applied Analysis 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/835310.

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Abstract (sommario):
We consider a predator-prey system with Michaelis-Menten type functional response and two delays. We focus on the case with two unequal and non-zero delays present in the model, study the local stability of the equilibria and the existence of Hopf bifurcation, and then obtain explicit formulas to determine the properties of Hopf bifurcation by using the normal form method and center manifold theorem. Special attention is paid to the global continuation of local Hopf bifurcation when the delaysτ1≠τ2.
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Ronellenfitsch, U., K. Meisenbacher, M. Ante, M. Grilli e D. Böckler. "Association between operation volume and postoperative mortality in elective endovascular repair of infrarenal abdominal aortic aneurysms: systematic review—continuation". Gefässchirurgie 25, S1 (dicembre 2020): 12–18. http://dx.doi.org/10.1007/s00772-020-00723-3.

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Abstract Background Many surgical interventions show an inverse association between case volume per hospital/surgeon and perioperative mortality. In the first part of this systematic review it was shown that such an association also exists for the open treatment of infrarenal aortic aneurysms. The second part now examines a possible association with endovascular treatment of infrarenal aortic aneurysms. Objective In a systematic review, the data available on the association between the case volume per hospital/surgeon and perioperative mortality in elective endovascular treatment of infrarenal aortic aneurysms are presented. Materials and Methods Systematic research using defined keywords was carried out. All original works comparing elective endovascular treatment of an infrarenal aortic aneurysm in a “high volume” center with a “low volume” center or by a “high volume” surgeon with a “low volume” surgeon, as defined in each study, were included. Results After deduplication, the literature search produced 1,021 hits. Of these, 16 publications fulfilled the inclusion criteria. With regard to the thresholds for the definition of high volume and low volume, there was marked heterogeneity between individual studies. Twelve of the 15 studies showed a significantly lower mortality in high volume than in low volume centers. The effect measures, usually odds ratios, were between 0.43 and 0.91. In the comparison between high volume and low volume surgeons, there was no difference in mortality in any of the five studies included. Discussion The available data on the association between case volume per hospital and surgeon and the perioperative mortality in elective endovascular treatment of infrarenal aortic aneurysms consistently show that patients operated on in high volume centers have a lower mortality. The volume per surgeon seems to have no influence on perioperative mortality. To achieve the lowest perioperative mortality possible in endovascular treatment of infrarenal aortic aneurysms, centralization with high volume per hospital should be aimed for, taking into consideration the context of the health care system.
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Amano, T., S. Shinzaki, T. Tashiro, Y. Otake, M. Tani, T. Yoshihara, S. Iwatani et al. "P673 Strategy of selecting anti-TNF agent in patients with Crohn’s disease: A multi-centre retrospective cohort study by the Osaka gut forum". Journal of Crohn's and Colitis 14, Supplement_1 (gennaio 2020): S551. http://dx.doi.org/10.1093/ecco-jcc/jjz203.801.

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Abstract Background Previous reports showed that disease activity before treatment affected long-term continuation of anti-tumour necrosis factor (anti-TNF) therapy in patients with Crohn’s disease (CD). However, there is no consensus about which anti-TNF agent should be selected dependent on patient’s condition. The aim of this study was to investigate factors affecting the continuation period of anti-TNF therapy and to clarify how to select each anti-TNF agent in patients with CD. Methods This was a retrospective multicenter cohort study of consecutive patients who started anti-TNF therapy (infliximab: IFX or adalimumab: ADA) as an induction therapy from January 2010 to March 2019 at 16 hospitals participating in the Osaka Gut Forum. We excluded patients who did not respond to therapy or had toxic events within 8 weeks. Factors affecting the continuation period of each anti-TNF agent such as backgrounds, blood tests, clinical features before treatment and concomitant medications were analyzed by the Cox proportional hazards model. The cumulative continuation rate of each agent was analyzed by the Kaplan–Meier method and evaluated by log-rank test. Results A total of 250 patients were enrolled (IFX /ADA; 138 /148 treatments, bio-naïve; 73%, median age; 36 years [Interquartile range (IQR); 24–46], median disease duration; 2.0 years [0.0–11.0], median observation period; 4.5 years [3.9–5.0]). Median Harvey–Bradshaw Index (HBI), C-reactive protein (CRP) and Albumin (Alb) were 5 [3–8], 0.71 mg/dl [0.14–2.04] and 3.5 g/dl [3.0–4.0], respectively. In patients with Alb ≥3.5 g/dl before treatment (median value), patients treated with IFX showed no significantly higher continuation rate than those with ADA. However, in those with Alb &lt;3.5 g/dl, patients treated with IFX (N =82) showed significantly higher continuation rate than those with ADA (N = 50) (p = 0.007). In the observation period, 50%/34% of patients treated with IFX /ADA increased dose and 29% /38% of them concomitantly used azathioprine. In patients with Alb &lt;3.5g/dl, by univariate analysis, stricturing and penetrating disease (B2 and B3/B1) [hazard ratio (HR); 4.18, 95% Confidence interval (CI); 1.83–12.0], disease duration [HR; 3.57, 95% CI; 1.16–9.77], and IFX/ADA [HR; 0.48, 95% CI; 0.28–0.83] were extracted as factors affecting continuation period of anti-TNF therapy. Furthermore, B2 and B3/B1 [HR; 3.80, 95% CI; 1.60–11.2] and IFX /ADA [HR; 0.49, 95% CI; 0.26–0.92] were extracted by multivariate analysis. After 8 weeks after treatment, the increase in Alb level was significantly higher in patients with IFX than those with ADA (p = 0.006), although there was no difference in HBI and CRP. Conclusion When serum Alb level is less than 3.5 g/dl before treatment, IFX can be used longer than ADA for CD patients.
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Mude, Swetha, Anju Singh, Vanita Suri, Rimpi Singla, Rashmi Bagga, Vanita Jain e Snigdha Kumari. "Acceptability of contraceptive methods in lactating mothers in a tertiary centre". International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, n. 5 (26 aprile 2024): 1179–85. http://dx.doi.org/10.18203/2320-1770.ijrcog20241062.

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Background: High fertility rate, high maternal mortality and high infant mortality rates are the shared problems of the all the developing countries of the world. According to Directorate of Health Services surveys, 40% of women who intend to use a family planning method in the first year postpartum are not using one. Contraceptive use is negligible among postpartum women, particularly young mothers. We aimed to determine the reasons for acceptability, non-acceptability, side effects and continuation of four contraceptive methods condoms, Depotmedroxyprogesterone acetate, (DMPA), copper intrauterine contraceptive devices (IUCD), progesterone only pills (POPs) in lactating mother after 6 weeks of delivery. Methods: A total of 200 healthy nursing mothers, who needed contraception were enrolled in this prospective observational study. Women were explained about all four contraceptive methods used for the study. The reason for accepting a particular method was sought. The study participant were followed up at third and sixth month and side effects, failure rate, continuation rates, reasons for discontinuation of method were assessed. Results: The most acceptable method was condom (40.5%) followed by DMPA (31%), IUCD (20.5%) and POPs (8%). The most common reason for selection of condom was fear of side effects with other methods (66%). Long acting method like DMPA and IUCD has good continuation rate of 87% and 85% respectively. Failure of contraception was seen only with condoms (2.8%). Conclusions: This study showed condoms was most acceptable method but had failure whereas DMPA and Cu-IUCD have high continuation rate with no failure.
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Seo, Young Kyung, Jeongok Park, Jin-Hee Park e Sue Kim. "What influences aromatase inhibitor continuation intention among breast cancer survivors?" Korean Journal of Women Health Nursing 27, n. 1 (31 marzo 2021): 49–57. http://dx.doi.org/10.4069/kjwhn.2021.01.19.

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Purpose: Aromatase inhibitors (AIs) are widely prescribed for postmenopausal women with breast cancer and are known to cause musculoskeletal pain. This study aimed to identify factors associated with AI continuation intention among breast cancer survivors (BCS). Methods: A cross-sectional survey was conducted on 123 BCS (stages I–III), who had been taking AIs for at least 6 weeks. Participants were recruited from a cancer center in Goyang, Korea, from September to November 2019. Descriptive statistics, Welch analysis of variance, Pearson correlation coefficients, and simple linear regression were used for the analysis.Results: Belief in endocrine therapy was a significant predictor of AI continuation intention (β=.66, p<.001). The majority of participants (87.0%) reported experiencing musculoskeletal pain since taking AIs and the score for the worst pain severity within 24 hours was 5.08±2.80 out of 10. Musculoskeletal pain, however, was not associated with AI continuation intention. Fear of cancer recurrence (FCR) was clinically significant (≥13) for 74.0% of the respondents (mean, 17.62±7.14). Musculoskeletal pain severity and pain interference were significantly associated with FCR (r=.21, p<.05; r=.35, p<.01, respectively). Pain interference was significantly associated with belief in endocrine therapy (r=–.18, p<.05). Conclusion: AI continuation intention can be modified by reinforcing patients’ belief in endocrine therapy. Musculoskeletal pain may have a negative effect on belief in endocrine therapy and increase FCR among BCS. Thus, awareness of musculoskeletal pain during AI therapy should be raised and further research is required to develop multidisciplinary pain management strategies and clinical guidelines to reinforce belief in endocrine therapy.
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Bektaş, M., B. Çelik, B. Ince, Y. Yalçinkaya, B. Artim-Esen, A. Gül, M. L. Ocal e M. Inanc. "POS0142 MINIMAL DISEASE ACTIVITY IN PATIENTS WITH PSORIATIC ARTHRITIS AND ASSOCIATED FACTORS: REAL LIFE DATA FROM A SINGLE CENTER". Annals of the Rheumatic Diseases 80, Suppl 1 (19 maggio 2021): 282.3–283. http://dx.doi.org/10.1136/annrheumdis-2021-eular.714.

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Background:Psoriatic arthritis (PsA) is a heterogeneous disease and GRAPPA have proposed Minimal disease activity (MDA) as a composite outcome measure and has been validated in PsA.Objectives:In this study, we aimed to evaluate the characteristics, MDA frequencies, first biological disease modifying antirheumatic drugs (b-DMARD) continuation rate and associated factors in our PsA cohort.Methods:PsA patients who fulfilled the CASPAR classification criteria and had at least six months of follow-up data were evaluated cross-sectionally for MDA.Clinical data were collected from patient charts with standard forms.b-DMARD treatment was initiated in patients who did not respond to at least one conventional synthetic (cs) DMARD for at least three months. Only anti-TNFs were used as a first line b-DMARD therefore secukinumab (Secu) was used after first line b-DMARD treatment. Adalimumab, certolizumab, etanercept, golimumab were grouped as subcutaneous (s.c) anti-TNFs. MDA was defined as meeting five out of seven criteria during follow-up [1].Results:One hundred seventy-two patients (61% female) were included into the analysis. The mean follow-up time was 105.4±76 (6-444) months and the mean age was 50.2±13.3 (16-81) years. Mean age of onset for PsA was 38±11.9 (11-79) years; mean PsA and PsO duration were 140±90.7 (7.9-528) and 253±138 (0-756) months, respectively. Methotrexate was the most commonly used (88 %) cs-DMARD and biological DMARDs were used in 74 patients (43.3%)Overall, 95 patients (55.2 %) were observed at MDA which was significantly lower in b-DMARD users compared to only cs-DMARD users (45.9 % vs 61.9 %; p=0.038, OR: 4.3). MDA did not differ according to PsA subtypes. The addition of cs-DMARD treatment to b-DMARDs did not affect MDA frequency In univariate analysis; higher MDA frequency was associated with older age (p=0.002), longer PsO duration (p=0.036), late onset of PsA (p=0.007) and continuation of first b-DMARD (OR:13.9 p<0.001). In multivariate analysis, older age (OR:1.3;95 % CI:1.02-1.68), late onset PsA (OR:1.03; 95 % CI:1.01-1.067) and continuation of first b-DMARD (OR:46.8; 95 % CI:1.6-1371) were associated with MDA.Conclusion:Although frequency of MDA in our cohort was consistent with previous reports, a significant number of patients could not achieve MDA. Frequency of MDA was found to be lower in b-DMARD users compared to cs-DMARD users, possibly resulted from initiation of b-DMARD in patients with higher disease activity. Higher MDA rate was associated with higher continuation rate at first line b-DMARD treatment (TNF-inhibitor) and decreased gradually after b-DMARD switches. Although combined use of cs-DMARD with b-DMARDs did not increase the frequency of MDA, it was associated with higher b-DMARD retention. MDA is a useful outcome measure in daily follow-up of PsA patients and the importance of reaching sustained MDA for prognosis should be investigated further.References:[1]Coates, L.C., J. Fransen, and P.S. Helliwell, Defining minimal disease activity in psoriatic arthritis: a proposed objective target for treatment. Ann Rheum Dis, 2010. 69(1): p. 48-53.Table 1.b-DMARD responses, continuation rate and frequency of achieving MDA in patients with PsAb-DMARD treatmentMean (median) duration (month)Continuation rate n, (%)Primary inefficacy n, (%)Secondary inefficacy n, (%)MDAn, (%)First line b-DMARD (n=74)50.4 (36)37 (50)9 (24.3)17 (46)34 (45.9) *s.c TNF inhibitors (n=62; 83.8 %)50.8 (35.5)32 (51.7)8 (26.7)9 (30)31 (50) Infliximab (n=12; 16.2 %)13.8 (11)3 (25)1 (11.1)7 (77.8)3 (25)Second line b-DMARD (n=29)28.4 (13.5)15 (51.7)5 (35.7)3 (21.4)8 (27.6) *s.c TNF inhibitors (n=22; 75.9 %)28.6 (15)11 (50)4 (36.4)2 (18.2)5 (22.7) Infliximab (n=5; 17.2 %)35.2 (36)3 (60)--2 (40) Secukinumab (n=2; 6.9 %)9 (9)1 (50)1 (50)-1 (50)s.c:subcutaneousFigure 1.Comparison of b-DMARD retention according to MDA status in patients with ongoing first line b-DMARD treatment Log rank: p=0.001Disclosure of Interests:None declared
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Dewata, Evada, e Hadi Jauhari. "The Readiness for Implementation of Financial Management Patterns of Regional Public Services Agency at Public Health Center". Journal of Accounting and Strategic Finance 4, n. 2 (30 novembre 2021): 191–206. http://dx.doi.org/10.33005/jasf.v4i2.221.

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The purpose of the study is to determine the readiness of Lais public health center and Teluk Kijing public health center of Musi Banyuasin District, South Sumatra Indonesia, in managing finances of regional public service agencies (BLUD). Time of research from March-July 2021. Used the types of descriptive qualitative research to review the documents, observation, and in-depth interviews to the research subject as many as 10 (ten) informants. The triangulation technique is used in testing the validity of the data. The research result showed that Lais public health center and Teluk Kijing public health center were ready to implement the financial management pattern of BLUD, which can be seen from the results of input analysis, process, and output from the analysis of stakeholder, related commitment, knowledge and responsibilities, funding (money), infrastructure (materials) and methods, in addition, substantive requirements, technical requirements, and administrative requirements have been carried out. The results of this study have implications related to the preparation and continuation of the implementation of the BLUD Public Health Center financial management pattern. Based on its limitation, it is still possible for other local governments who have the same contextual conditions to use these results as an input when preparing the BLUDs financial management pattern.
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Vedunova, M., e O. Abaeva. "The organization of practical training of medical students in the context of the COVID — 2019 pandemic". Glavvrač (Chief Medical Officer), n. 9 (1 settembre 2020): 39–44. http://dx.doi.org/10.33920/med-03-2009-03.

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The article is devoted to the problems of organizing practical training of medical students of the first, second and third years of study in the conditions of the COVID-19 pandemic. The authors note that the best option is to organize practical training of students on the basis of a simulation center with the involvement of nurses and doctors of medical organizations in educational activities. At the same time, the authors consider this measure forced and Express hope for the continuation of the traditional form of practical training in the next academic year.
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Ce, Win, Hanny Juwitasary e Hendro Hendro. "System Requirement in View Of Users and Process for Content Management and Academic Support System for Computer Laboratory (Case Study: Software Laboratory Center Binus University)". ComTech: Computer, Mathematics and Engineering Applications 6, n. 1 (1 marzo 2015): 55. http://dx.doi.org/10.21512/comtech.v6i1.2286.

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The system for Laboratory Information will take focus on determining the need for information systems related to the management, content development and academic management in the laboratory. These processes will focus on understanding the need and system requirement for a laboratory information system that focus on content management and the way to design a process to make sure the continuation of content creation can be done. With the design of the laboratory information system is expected to serve as a sample in the development of similar application for the course in general. The methodology to be used is to use the study of literature, design, and testing of laboratory information systems.
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Boytsov, S. A., O. M. Drapkina, E. V. Shlyakhto, A. O. Konradi, Yu A. Balanova, Yu V. Zhernakova, V. A. Metelskaya, E. V. Oshchepkova, O. P. Rotar e S. A. Shalnova. "Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Ten years later". Cardiovascular Therapy and Prevention 20, n. 5 (12 settembre 2021): 3007. http://dx.doi.org/10.15829/1728-8800-2021-3007.

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The growing weight of noncommunicable diseases, primarily cardiovascular diseases (CVDs), is a great threat to the health of population worldwide, worsening the quality of life and reducing life expectancy. Realization of this threat led to initiation of epidemiological study by the Russian Ministry of Health to investigate the prevalence of CVDs and their risk factors, since it is CVDs that specify the high allcause mortality in Russia. In the modern history of epidemiology of non-infectious disease, the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study occupies a special place. This is the largest epidemiological study, which is considered as a continuation of preventive activity in order to obtain unbiased information on epidemiological characteristics of population in Russian regions. To conduct the study, the Research Organizing Committee of ESSE-RF study was created and a protocol was developed. All interested scientists and experts from following three centers took part in the work: National Medical Research Center for Therapy and Preventive Medicine, Almazov National Medical Research Center, National Medical Research Center of Cardiology. The Russian regions were justified and selected for participation. In 2012-2014 ESSE-RF study, 13 following Russian regions took part: Volgograd, Vologda, Voronezh, Ivanovo, Kemerovo, Tyumen Oblasts; Krasnoyarsk and Primorsky Krai; the Republic of North Ossetia (Alania); cities of Orenburg, Samara, St. Petersburg and Tomsk. All participated regions used a single study protocol, while biochemical parameters were determined in Federal centers using the same equipment and reagent kits. The paper presents some of the most interesting results that indicate a change in Russian epidemiological situation over the past few years. After the end of cross-sectional study, a field of priority research areas was formed in each center.Conclusion. Epidemiological studies are the most important scientific tool for assessing the prevalence of diseases, their risk factors, as well as predicting adverse events. Based on the results obtained, healthcare system and medical community determine priorities and develop related strategies (population-based and high-risk strategies). For their implementation, a regulatory and legal framework is being created.
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Sallam, I., G. Amira e A. Youssri. "The Role of the Psychooncology Team in the Multidisciplinary Team Management of Breast Cancer Patients - From Diagnosis to After Treatment: A Qualitative Study at MISR Cancer Center". Journal of Global Oncology 4, Supplement 2 (1 ottobre 2018): 114s. http://dx.doi.org/10.1200/jgo.18.79400.

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Background: According to the cultural and socioeconomic factors, breast cancer patients (BCP) experienced a relatively low health-related quality of life (Qol) during the journey of breast cancer treatment, that influence patient adaptation to the situation from diagnosis to after treatment. And the further effect on either starting the treatment or its continuation. This merited conducting a qualitative study to explore the importance of the psychooncological approach to BCP and the impact on commencing and continuation of treatment and follow-up. Aim: To describe the impact and importance of the psychooncology team in the cancer center and the effect of their approach on the BCP's Qol. Methods: The study involved 114 interviewed participants, excluding patients with wide variety of chronic illnesses, only 91 patients are the focused study group. Of which 11 patients group (1) refused to join the psychooncological approach due to cultural, and socioeconomic issues, and 80 patients group (2) joined and followed up by the team. Both groups are regularly surveyed. Qualitative and quantitative measurements were used. Data were collected as follows, at time of diagnosis, after surgery and after chemo-radiation therapies from group (1) and for group (2) after the psychooncology team management and care. Developing the psychooncology team for the cancer center. 2 psychooncologists, 5 psychoeducating nurses and a group therapy sessions at a world standard levels of care with ethics committee approvals, and caring for patients' privacy. Close follow-up and evaluation of the performance and Qol of our BCP, raising the awareness about psychoeducation and psychological approach importance for BCP that would help them cope with daily life challenges to improve Qol. Results: Category Group N. Diagnosis related depression N. Surgery related depression N. Treatment related depression Free of depression Group (1) No= 11 3 (27%) 2 (18%) 5 (45%) 1 (10%) Group (2) No= 80 12 (15%) 9 (11.3%) 23 (28.7%) 36 (45%) Conclusion: Results indicate that the most critical depressing points is at time of diagnosis and chemo-radiation therapy. Group (2) has positive indication and alternation on the level of Qol and a significant improvement on level of depression when compared with group (1). This study highlighted the importance of psychooncology team in BCPs' survivorship. It also brings to attention the important role of the government, health policy makers and health plans toward enriching all cancer centers with the psychooncology team. To maximize health and health care for BCP.
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Taghadossi, Masood, Mohammad Naghi Farahani e Morteza Manteghi. "Factors Influencing the Formation, Continuation, and Dissolution of Marital Relationships in Iran in 2022: A Qualitative Analysis". Applied Family Therapy Journal 5, n. 2 (2024): 55–67. http://dx.doi.org/10.61838/kman.aftj.5.2.7.

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Objective: The aim of this study was to identify the factors influencing the formation, continuation, and dissolution of Iranian marriages in the year 2022. Methods: This research utilized a qualitative method based on the Strauss and Corbin approach. A purposive selection of 10 experts, either faculty members or influential figures in decision-making centers for marriage and family affairs, were deeply interviewed. The data obtained from these experts provided a semi-structured questionnaire for interviews with 36 individuals, divided into three groups: formation, continuation, and dissolution of marriages. After each interview, data were coded and categorized according to the Strauss and Corbin method. Findings: In total, 2950 primary codes, 462 secondary codes, 97 concepts, 27 subcategories, and 9 main categories were identified, including external couple factors affecting formation, continuation, and dissolution; internal couple factors affecting formation, continuation, and dissolution; and individual factors affecting formation, continuation, and dissolution. Conclusion: The results indicated that the formation of marriage is influenced more by external couple factors than by any other factors. Although the continuation and dissolution of marriage are influenced by the nature of their formation, individual factors become important in these stages. It can be inferred that focusing on external couple factors before individual and internal couple factors in pre-marital counseling, and prioritizing individual factors in couple therapy and divorce counseling, may be more effective. It is recommended that the results of this study be used in planning, research, and therapeutic interventions in the field of marriage
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Farrokh, Salia, Amber C. Castle, Mojdeh Heavner e Margaret A. Pisani. "Continuation Rate of Atypical Antipsychotics After Discharge When Initiated in the Intensive Care Unit". Journal of Pharmacy Practice 30, n. 3 (28 aprile 2016): 342–46. http://dx.doi.org/10.1177/0897190016645026.

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Purpose: The frequency with which atypical antipsychotics initiated in the intensive care unit (ICU) is unknown. While there is lack of evidence to support the exact duration of treatment, antipsychotics should not be continued chronically for agitation and psychosis related to critical illness. The objective of this study was to determine whether atypical antipsychotics initiated in the ICU at a large tertiary academic medical center were continued after hospital discharge. Safety outcomes were also assessed. Materials: A total of 1023 patients who received atypical antipsychotics during ICU stay were identified. Patients were assessed in a pseudo-randomized fashion until a sample of 191 patients was reached. After review of the exclusion criteria, the final study population was 100 patients. When antipsychotics were discontinued, progress notes were reviewed to identify the reason for discontinuation. Safety outcomes were assessed based on physician documentation in the medical charts. Results: Atypical antipsychotics were continued in 23% of patients. Atypical antipsychotics were discontinued in 1 patient due to QTc prolongation. Conclusions: Atypical antipsychotics initiated in the ICU are frequently continued after hospital discharge. Given the known risks associated with extended therapy, initiatives are needed to prevent inappropriate continuation.
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Kashyap, Ankur, Willy Govaerts, Debasish Bhattacharjee e Hemanta Sarmah. "Bifurcation analysis of a predator-prey system with density dependent disease recovery". Filomat 36, n. 20 (2022): 6897–922. http://dx.doi.org/10.2298/fil2220897k.

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The center manifold is an invariant manifold that plays a crucial role in the bifurcation analysis of dynamical systems. The center manifold existence theorem assures the local existence of an invariant submanifold of the state space of a dynamical system around a non-hyperbolic equilibrium point. Center manifold theory is essential in the reduction of different bifurcation scenarios to their normal forms. Our study focuses on a predator-prey interactive system with density-dependent growth in predators subject to a contagious disease. The disease is assumed to be horizontally transmitted, and the rate of recovery of the infected predator is assumed to be density-dependent. At the trivial (zero) equilibrium, the center manifold is calculated whose dynamical behaviour is similar to that of the original system. Further, using the center manifolds, the normal form of a Hopf bifurcation point is determined fromwhich the criticality of the system can be deduced. Finally, numerical simulations are performed with biologically plausible parameters to substantiate the analytical findings. Using numerical continuation methods we detect Generalized Hopf and Zero-Hopf bifurcation points. We discuss their normal form coefficients, compute their two-parameter unfoldings and relate these results to the mathematical theory of codimension two bifurcations.
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Noveyani, Adistha Eka, e Santi Martini. "Evaluation the Pulmonary Tuberculosis Control Program with Strategy DOTS in Puskesmas Tanah Kalikedinding Surabaya". Jurnal Berkala Epidemiologi 2, n. 2 (1 maggio 2014): 251. http://dx.doi.org/10.20473/jbe.v2i2.2014.251-262.

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ABSTRACTStrategy DOTS is the tuberculosis control programs. The program has implemented in Tanah Kalikedinding Health Center and has expected to reach CDR ≥ 70% and SR ≥ 85%, which closely related to the management of health centers. This study aimed to evaluate the implementation of the DOTS program in health center whose the results associated with indicators of tuberculosis. This was a descriptive design study with the population was all pulmonary specialist, tuberculosis officers and laboratory personnel and pulmonary tuberculosis patients. The number of Tuberculosis patient respondents was 32 respondents. Samples were chosen using purposive sampling. Data collected by interview questionnaire and checklist. The variables were the finding case, the TB treatment, the enabling factor and inhibiting factor, recording and reporting, and result of tuberculosis indicators. This study resulted that CDR in 2013 was 112% already reached the national target ≥ 70%. This success related to the finding case almost all patients > 2 weeks of cought and all (100%) patients were examinated sputum and diagnosed according to the steps of tuberculosis diagnosis in Indonesia Department of Health guidelines. While SR in 2013 was 65.5% did not reach the target ≥ 85%. It was caused of there are patients who did not have a taking drug observer (PMO). All (100%) patients ever forgot taking anti tuberculosis drugs. Change in schedule of visit to the continuation phase be 2×/month caused patients to forget taking anti tuberculosis drugs. The enabling factor was counseling routinely by health care workers in health center. Inhibiting factor was distance to health center by majority (65,5%) patients were > 1 km. So they needed vehicle to go to the health center. Recording and reporting using electronic systems and being reported by online. So it is expected all TB patients were expected have a taking drug observer and optimizing the role of the a taking drug observer to increase success rate.Keywords: DOTS strategy, Case Detection Rate, Success Rate, evaluation, Tuberculosis
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Noveyani, Adistha Eka, e Santi Martini. "Evaluation the Pulmonary Tuberculosis Control Program with Strategy DOTS in Puskesmas Tanah Kalikedinding Surabaya". Jurnal Berkala Epidemiologi 2, n. 2 (1 maggio 2014): 251. http://dx.doi.org/10.20473/jbe.v2i22014.251-262.

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Abstract (sommario):
ABSTRACTStrategy DOTS is the tuberculosis control programs. The program has implemented in Tanah Kalikedinding Health Center and has expected to reach CDR ≥ 70% and SR ≥ 85%, which closely related to the management of health centers. This study aimed to evaluate the implementation of the DOTS program in health center whose the results associated with indicators of tuberculosis. This was a descriptive design study with the population was all pulmonary specialist, tuberculosis officers and laboratory personnel and pulmonary tuberculosis patients. The number of Tuberculosis patient respondents was 32 respondents. Samples were chosen using purposive sampling. Data collected by interview questionnaire and checklist. The variables were the finding case, the TB treatment, the enabling factor and inhibiting factor, recording and reporting, and result of tuberculosis indicators. This study resulted that CDR in 2013 was 112% already reached the national target ≥ 70%. This success related to the finding case almost all patients > 2 weeks of cought and all (100%) patients were examinated sputum and diagnosed according to the steps of tuberculosis diagnosis in Indonesia Department of Health guidelines. While SR in 2013 was 65.5% did not reach the target ≥ 85%. It was caused of there are patients who did not have a taking drug observer (PMO). All (100%) patients ever forgot taking anti tuberculosis drugs. Change in schedule of visit to the continuation phase be 2×/month caused patients to forget taking anti tuberculosis drugs. The enabling factor was counseling routinely by health care workers in health center. Inhibiting factor was distance to health center by majority (65,5%) patients were > 1 km. So they needed vehicle to go to the health center. Recording and reporting using electronic systems and being reported by online. So it is expected all TB patients were expected have a taking drug observer and optimizing the role of the a taking drug observer to increase success rate.Keywords: DOTS strategy, Case Detection Rate, Success Rate, evaluation, Tuberculosis
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Wagner, Ariela, Jangus Whitner, Ariel Williams, Kristina Hirt, Tessa Miracle e Alexa Valentino. "Community Health Center 340B Program: A Qualitative Study of the Experiences of Patients with Diabetes". INNOVATIONS in pharmacy 14, n. 3 (2 ottobre 2023): 8. http://dx.doi.org/10.24926/iip.v14i3.5445.

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Background: The 340B Drug Pricing Program provides discounted drug prices to safety-net entities which help stretch scarce resources to expand comprehensive services and treat more vulnerable patients. The program has received criticism questioning whether the original intentions are being accomplished. Objective: This qualitative study aimed to understand lived experiences of patients accessing high-cost injectable diabetes medication(s) through a 340B Prescription Cash Discount Program (PCDP) provided at a community health center. Methods: This qualitative study utilized semi-structured individual interviews. We invited patients ≥18 years old with diabetes for >1 year who utilized the 340B PCDP to fill an injectable diabetes medication at least twice between 3/1/2020-3/1/2021 to participate. Trained personnel interviewed ten participants in 11/2021-2/2022 and completed thematic analysis of the transcribed interviews. Results: Themes included 340B feedback, benefits of 340B, consequences of being without 340B, community pharmacy experience, and use of other services. Participants deemed the 340B program as a “lifesaver.” Perceived benefits of the program included improved diabetes control and savings that made their prescriptions more affordable. Consequences of being without the program include that medication was too expensive to take as prescribed and rationing/skipping doses. Participants were pleased with the accessibility of the network of contract pharmacies and described benefiting from services supported by 340B savings. Conclusions: Recent criticisms question whether the 340B program accomplishes its original intentions of stretching scarce federal resources to help safety-net entities expand services and treat more patients. This study provides insight into the personal impact of the 340B program on underserved patients with chronic disease accessing high-cost medication(s). Findings highlight crucial strengths of the program from the patient perspective, which policymakers and other stakeholders should consider to provide support for the continuation of these services.
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Ruwayda, Ruwayda, e M. Dody Izhar. "Analisis Program Kemitraan Bidan dan Dukun Bayi di Kota Jambi". Jurnal Ilmiah Universitas Batanghari Jambi 20, n. 2 (1 luglio 2020): 424. http://dx.doi.org/10.33087/jiubj.v20i2.952.

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Based on the results of the 2018 Riskesdas, the proportion of birth attendants in women aged 10 - 54 years still has 6.7% of pregnant women giving birth not with health workers. Aur Duri Health Center is one of the Puskesmas from 20 Puskesmas in Jambi City, which in 2018 occurred 1 death of pregnant women who were helped by TBAs in Penyengat Rendah Village, Telanai Pura Sub-District. This incident should not have happened considering the location of the Aur Duri Puskemas area was still in the Jambi City Center and access to health workers, health centers and hospitals was very smooth and easy to reach. There are still 12 traditional birth attendants in the work area of Aur Duri Health Center in 2018. This study aims to analyze the implementation of partnership programs for midwives and traditional birth attendants in the work area of Aur Duri Health Center, Jambi City: input, process and output variables. Data collection techniques used the method of in-depth interviews, Focus Group Discussion (FGD), and document review.Based on the results of the study it was known that the partnership between midwives and traditional birth attendants had not gone well, while the partnership between midwives and traditional birth attendants in the Aur Duri Community but there was no continuation of implementation of these activities. It is recommended that the Health Office and Aur Duri Puskesmas provide support and guidance and can allocate funds for partnership activities between midwives and traditional birth attendants so that it can be a solution to achieving KIA coverage targets, especially labor assistance by health workers and suppressing death cases. In addition, it is necessary to conduct monitoring and evaluation in the implementation of this partnership so that it can run well
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Medler, Corey J., Mary Whitney, Juan Galvan-Cruz, Ron Kendall, Rachel Kenney, Susan L. Davis e Susan L. Davis. "182. Missed Opportunities to Discontinue Unnecessary Vancomycin During Pharmacist Therapeutic Monitoring". Open Forum Infectious Diseases 7, Supplement_1 (1 ottobre 2020): S98. http://dx.doi.org/10.1093/ofid/ofaa439.226.

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Abstract Background Unnecessary and prolonged IV vancomycin exposure increases risk of adverse drug events, notably nephrotoxicity, which may result in prolonged hospital length of stay. The purpose of this study is to identify areas of improvement in antimicrobial stewardship for vancomycin appropriateness by clinical pharmacists at the time of therapeutic drug monitoring (TDM). Methods Retrospective, observational cohort study at an academic medical center and a community hospital. Inclusion: patient over 18 years, received at least three days of IV vancomycin where the clinical pharmacy TDM service assessed for appropriate continuation for hospital admission between June 19, 2019 and June 30, 2019. Exclusion: vancomycin prophylaxis or administered by routes other than IV. Primary outcome was to determine the frequency and clinical components of inappropriate vancomycin continuation at the time of TDM. Inappropriate vancomycin continuation was defined as cultures positive for methicillin-susceptible Staphylococcus aureus (MRSA), vancomycin-resistant bacteria, and non-purulent skin and soft tissue infection (SSTI) in the absence of vasopressors. Data was reported using descriptive statistics and measures of central tendency. Results 167 patients met inclusion criteria with 38.3% from the ICU. SSTIs were most common indication 39 (23.4%) cases, followed by pneumonia and blood with 34 (20.4%) cases each. At time of vancomycin TDM assessment, vancomycin continuation was appropriate 59.3% of the time. Mean of 4.22 ± 2.69 days of appropriate vancomycin use, 2.18 ± 2.47 days of inappropriate use, and total duration 5.42 ± 2.94. 16.4% patients developed an AKI. Majority of missed opportunities were attributed to non-purulent SSTI (28.2%) and missed MRSA nares swabs in 21% pneumonia cases (table 1). Conclusion Vancomycin is used extensively for empiric treatment of presumed infections. Appropriate de-escalation of vancomycin therapy is important to decrease the incidence of adverse effects, decreasing hospital length of stay, and reduce development of resistance. According to the mean duration of inappropriate therapy, there are opportunities for pharmacy and antibiotic stewardship involvement at the time of TDM to optimize patient care (table 1). Missed opportunities for vancomycin de-escalation Disclosures All Authors: No reported disclosures
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Chaudhri, Imran, Farrukh M. Koraishy, Olena Bolotova, Jeanwoo Yoo, Luis A. Marcos, Erin Taub, Haseena Sahib et al. "Outcomes Associated with the Use of Renin-Angiotensin-Aldosterone System Blockade in Hospitalized Patients with SARS-CoV-2 Infection". Kidney360 1, n. 8 (22 giugno 2020): 801–9. http://dx.doi.org/10.34067/kid.0003792020.

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BackgroundData regarding the benefits or harm associated with the continuation of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), especially the effect on inflammation, in patients who are hypertensive and hospitalized with coronavirus disease 2019 (COVID-19) in the United States are unclear.MethodsThis is a single-center cohort study of patients sequentially hospitalized with COVID-19 at Stony Brook University Medical Center from March 7, 2020 to April 1, 2020, inclusive of these dates. Data collection included history of known comorbidities, medications, vital signs, and laboratory values (at admission and during the hospitalization). Outcomes include inflammatory burden (composite scores for multiple markers of inflammation), AKI, admission to the intensive care unit (ICU), need for invasive mechanical ventilation, and mortality.ResultsOf the 300 patients in the study cohort, 80 patients (27%) had history of ACEI or ARB use before admission, with 61% (49/80) of these patients continuing the medications during hospitalization. Multivariable analysis revealed that the history of ACEI or ARB use before hospitalization was not associated with worse outcomes. In addition, the continuation of these agents during hospitalization was not associated with an increase in adverse outcomes and predicted fewer ICU admissions (odds ratio, 0.25; 95% CI, 0.08 to 0.81) with a decrease in the severity of inflammatory burden (peak C-reactive protein, 6.9±3.1 mg/dl, P=0.03; peak inflammation score, 2.3±1.1 unit reduction, P=0.04).ConclusionsUse of ACEI or ARBs before hospitalization was not associated with adverse outcomes in COVID-19, and the therapeutic benefits of continuing ACEI or ARB in patients hospitalized with COVID-19 was not offset by adverse outcomes.
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Chumak-Horbatsch, Roma. "Early bilingualism: children of immigrants in an English-language childcare center". Psychology of Language and Communication 12, n. 1 (1 gennaio 2008): 3–27. http://dx.doi.org/10.2478/v10057-008-0001-2.

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Early bilingualism: children of immigrants in an English-language childcare center In this study, language views and home language practice of sixteen immigrant parents were documented and related to the dual language behaviors of their young children (ages 1:09 to 3;06) who were enrolled in a Toronto English-language childcare center. De Houwer's (1999) model of early bilingualism was applied to the minority language context and external factors were used to explain the short-lived active bilingualism of the younger children and the passive bilingualism of the preschoolers. Presenting mothers and fathers with separate questionnaires proved to be a valuable methodological tool, which revealed similar language thinking but different home language practice. Immigrant mothers were more committed to their children's L1 development than were fathers, a finding, which supports and extends the parental gender difference noted in earlier work (Gleason, 2005; Lyon, 1991; Lyon & Ellis, 1999). Negative effects of early L2 exposure on minority language children's incomplete L1, reported in earlier studies, were confirmed. A concrete outcome of the present study was the creation mylanguage.ca, a website intended to help immigrant parents understand their children's dual language learning. Even though the study presents a somewhat bleak picture of the continuation of L1, it concludes on an optimistic note, encouraging immigrant fathers to join forces with their L1-committed spouses and to help provide a nurturing L1 environment for their young children.
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Amelia, Rinita, Nilas Warlem, Dessy Abdullah e Satria Andhika. "Compliance Profile of Pulmonary Tuberculosis Patient Treatment Stage in Consuming Anti Tuberculosis Drugs (ATD) at Lubuk Buaya Health Center Padang". Science Midwifery 10, n. 4 (22 settembre 2022): 2737–46. http://dx.doi.org/10.35335/midwifery.v10i4.706.

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A well-prepared abstract enables the reader to identify the basic Tuberculosis (TB) is a disease caused by the microorganism Mycobacterium tuberculosis. According to the World Health Organization (WHO), the prevalence global of TB in 2018 was around 10 million people infected and caused 1.5 million deaths. Eradication TB, it is necessary to be aware of the patient himself because adherence to taking ATD is a key factor in the success of the treatment. The purpose of this study was to determine the compliance profile of pulmonary TB patients in consuming Anti-TB Drugs (ATD) at Lubuk Buaya Health Center, Padang City in 2019-2020. Type of research is descriptive research with cross-sectional study method and total sampling. Univariate data analysis is presented by distribution freququency. Data processing using the computerized SPSS program. The results of research showed 117 patients who met the inclusion and exclusion criteria. The most of patient is 26-45 years old, namely 51 people (43,6%). The Most of gender is male, namely 65 people (55,6%). The most job of patient is entreprenur, namely 35 people (29,9%). The most of education category is a middle category, namely 69 people (59,0%). The most of treatment stage is continuation stage, namely 99 people (84,6%). The most of ATD category is the first category , namely 100 people (85,5%), and the most patient to complied to taking ATD, namely 99 people (84,6%). This research was concluded that age 26-45 years old, gender is male, job is entreprenur, education is a middle category, stage of treatment is continuation category, the first category of ATD, patient to complied to taking ATD is the dominant profile pulmunary TB patient at Lubuk Buaya health center in 2019-2020.
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Damayanti, Meisika, e Surati Surati. "Profile of SGPT Levels in Multidrug Resistant Tuberculosis Patients (MDR-TB)". Jaringan Laboratorium Medis 2, n. 2 (22 settembre 2021): 68–74. http://dx.doi.org/10.31983/jlm.v2i2.7687.

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Multidrug Resistant Tuberculosis (MDR-TB) has recently become a health threat in Indonesia. The clinical management of MDR TB is more complicated than that of ordinary TB. Hepatotoxicity or commonly known as Anti-Tuberculosis Drug-induced Hepatotoxicity (ATDH) is a serious effect of OAT that often occurs. The basic parameter for diagnosing or following up the presence of impaired liver function is the SGPT examination. The purpose of this study was to describe the level of SGPT in MDR-TB patients at the Kendal District Health Center. This study is an observational (non-experimental) study with descriptive research criteria with a cross sectional approach which was conducted on 7 MDR-TB patients at Kendal I Health Center, Kaliwungu Health Center, and South Kaliwungu Health Center with total sampling technique. The results of the study: obtained SGPT levels in 7 patients with MDR-TB there were 7 research respondents (100%) had normal SGPT levels with the lowest level of 2.17 U/L and the highest level of 37.75 U/L and the average level of SGPT ie 18.01 U/L. TB mostly attacks the age group of 56-65 years (57%). Males (57%) were the patients with the most TB cases. The most OAT consumption time was in the continuation phase (100%). Diabetes is a disease that often accompanies TB patients. The conclusion of this study is that from 7 research subjects, MDR-TB patients had SGPT levels that were in the normal range.
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Doknic, Mirjana, Marko Stojanovic, Ivan Soldatovic, Tatjana Milenkovic, Vera Zdravkovic, Maja Jesic, Sladjana Todorovic et al. "Mapping the journey of transition: a single-center study of 170 childhood-onset GH deficiency patients". Endocrine Connections 10, n. 8 (1 agosto 2021): 935–46. http://dx.doi.org/10.1530/ec-21-0274.

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Objective To analyze metabolic parameters, body composition (BC), and bone mineral density (BMD) in childhood-onset GH deficiency (COGHD) patients during the transition period (TP). Design Single- center, retrospective study was performed on 170 consecutive COGHD patients (age 19.2 ± 2.0 years, range 16–25) transferred after growth completion from two pediatric clinics to the adult endocrine unit. Two separate analyses were performed: (i) cross-sectional analysis of hormonal status, metabolic parameters, BC, and BMD at first evaluation after transfer from pediatrics to the adult department; (ii) longitudinal analysis of BC and BMD dynamics after 3 years of GH replacement therapy (rhGH) in TP. Results COGHD was of a congenital cause (CONG) in 50.6% subjects, tumor-related (TUMC) in 23.5%, and idiopathic (IDOP) in 25.9%. TUMC patients had increased insulin and lipids levels (P < 0.01) and lower Z score at L-spine (P < 0.05) compared to CONG and IDOP groups. Patients treated with rhGH in childhood demonstrated lower fat mass and increased BMD compared to the rhGH-untreated group (P < 0.01). Three years of rhGH after growth completion resulted in a significant increase in lean body mass (12.1%) and BMD at L-spine (6.9%), parallel with a decrease in FM (5.2%). Conclusion The effect of rhGH in childhood is invaluable for metabolic status, BC, and BMD in transition to adulthood. Tumor-related COGHD subjects are at higher risk for metabolic abnormalities, alteration of body composition, and decreased BMD, compared to those with COGHD of other causes. Continuation of rhGH in transition is important for improving BC and BMD in patients with persistent COGHD.
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Sri Rahayu, Suharyo Hadisaputro, Syarief Taufik Hidayat e Anggorowati. "Characteristics and Related Factors to Breast Milk Production of Postpartum: Preliminary Study at Public Health Center of Semarang City". EMBRIO 14, n. 1 (31 maggio 2022): 118–25. http://dx.doi.org/10.36456/embrio.v14i1.5292.

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Approximately 38-63% of primiparous postpartum mothers experience lactation insufficiency, which has an impact on not breastfeeding their babies. The purpose of this study was to determine the characteristics and factors associated with postpartum mothers' milk production at the Public Health Center of Semarang City. This type of research is observational and cross-sectional design. The population of all postpartum women in Semarang City in October 2021, was taken by cluster random sampling at 8 selected health centers and a sample of 124 postpartum women. Methods of collecting data were questionnaires and data analysis with chi-square. The results of the research are the characteristics of mothers with an average age of 28 years, 56.5% of secondary education, 40% of primiparous parity, 59% of normal BMI, 92.7% of normal LILA, average age of the baby was 7 days, 82.3% of moderate anxiety level, 99.2% off good staff support, 58.9% of good surveillance worker support, 91.1% of good family support, 82.3% of more calorie intake of 2200 kcal, 62.1% of 1600 ml more fluid intake. There was a relationship between anxiety, family support, health volunteer support, calorie and fluid intake with breast milk production (p-value <0.05). There was no relationship between the support of health workers with postpartum mothers' milk production (p = 0.166). Mother’s psychological condition while breastfeeding, support from family, and health insurance are important things in increasing breast milk production as a continuation of breastfeeding and exclusive breastfeeding. In addition, calorie and fluid intake need to be considered to maintain the adequacy of mother's milk.
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Babo, Winarto, e Metty Mustikasari. "EVALUATION OF MOBILE APPLICATION BPJSTKU USING COBIT 5 FRAMEWORK (STUDY CASE: BPJS KETENAGAKERJAAN)". International Journal of Engineering Technologies and Management Research 8, n. 7 (3 agosto 2021): 103–14. http://dx.doi.org/10.29121/ijetmr.v8.i7.2021.963.

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BPJS as a social security to provides protection to all workers in Indonesian utilize especially mobile application in providing information and services to all BPJS customer anytime and anywhere without having to BPJS branch office. Beginning in 2019 BPJS has mobile application with the name as a continuation of BPJSTK Mobile has been made previously. The addition of new features and improvements to the mobile application apparently still provides problem and complaints from workers addressed to the BPJS branch office, BPJS complaints services, and BPJS contact center. For this reason, it’s necessary to evaluate the implementation of mobile application as a whole to assist BPJS in achieving the objectives to improving IT governance and management of BPJS . This study aims to evaluate the mobile application using the COBIT 5 which has been implemented in BPJS . In this case the evaluation will be carried out using , service, and support (DSS) domain and the domain monitor, evaluate, and assess (MEA) which in the end will be measured the capability level as well as recommendations for improvement and gap analysis on the mobile application .
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Hatchett, Gregory T., e Heather L. Park. "Revisiting Relationships between Sex-Related Variables and Continuation in Counseling". Psychological Reports 94, n. 2 (aprile 2004): 381–86. http://dx.doi.org/10.2466/pr0.94.2.381-386.

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This study examined the relationships between three sex-related variables (client sex, therapist sex, and dyad matching on sex) and continuation in counseling. 245 college students who were clients at three university counseling centers participated. Consistent with previous studies, women comprised 68.2% of the clients seeking services at these counseling centers. Clients' sex was significantly related to counseling duration, explaining 2.2% of the common variance. Female clients, on the average, attended 1.8 more sessions than male clients. However, neither the therapists' sex nor dyad matching on sex was significantly related to the duration of counseling. None of the sex-related variables correlated with premature termination of counseling. The results have implications for providing counseling and outreach services to male students. Despite relatively equivalent rates in the incidence of mental health problems, female students continue to comprise the majority of clients. Therefore, university counseling centers need to communicate their services better to male students in need of mental health services.
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Petrişor, Alexandru-Ionuţ, e Liliana Elza Petrişor. "2006-2012 Land Cover and Use Changes in Romania – An Overall Assessment Based on Corine Data". Present Environment and Sustainable Development 11, n. 2 (1 ottobre 2017): 119–27. http://dx.doi.org/10.1515/pesd-2017-0030.

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AbstractLand cover and use changes are an important component of the global changes, and in relationship with their transitional dynamics reflect the impact of socio-economic transition. This study is aimed at exploring the land cover and use changes occurred during 2006-2012 in Romania with respect to their spatial distribution over the regions of development and main transitional dynamics. The results suggest that the main drivers of change are deforestation and urbanization, accounting for 3/4 of all changes, and that the most affected regions are the northwest, southwest, center and northeast ones. Overall, the findings suggest a continuation of the trends from the previous periods, characteristic to transition economies.
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Starkweather, Sydney, Jonathan M. DePierro, Saadia Akhtar, Eleanore de Guillebon, Carly Kaplan, Sabrina Kaplan, Jonathan Ripp et al. "Predictors of Mental Health Service Utilization among Frontline Healthcare Workers during the COVID-19 Pandemic". International Journal of Environmental Research and Public Health 20, n. 7 (30 marzo 2023): 5326. http://dx.doi.org/10.3390/ijerph20075326.

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(1) Background: This study examined the prevalence and correlates of factors associated with self-reported mental health service use in a longitudinal cohort of frontline health care workers (FHCWs) providing care to patients with COVID-19 throughout 2020. (2) Methods: The study comprised a two-wave survey (n = 780) administered in April–May 2020 (T1) and November 2020–January 2021 (T2) to faculty, staff, and trainees in a large urban medical center. Factors associated with initiation, cessation, or continuation of mental health care over time were examined. (3) Results: A total of 19.1% of FHCWs endorsed currently utilizing mental health services, with 11.4% continuing, 4.2% initiating, and 3.5% ceasing services between T1 and T2. Predisposing and need-related factors, most notably a history of a mental health diagnosis and distress related to systemic racism, predicted service initiation and continuation. Among FHCWs with a prior mental health history, those with greater perceived resilience were less likely to initiate treatment at T2. Descriptive data highlighted the importance of services around basic and safety needs (e.g., reliable access to personal protective equipment) relative to mental health support in the acute phase of the pandemic. (4) Conclusions: Results may be helpful in identifying FHCWs who may benefit from mental health services.
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Vdovichena, Olha, e Ruslan Barbutsa. "RELEVANCE OF DESIGNING A HOTEL ESTABLISHMENT WITH A REHABILITATION CENTER FOR THE RECOVERY OF MILITARY SERVANTS". BULLETIN OF CHERNIVTSI INSTITUTE OF TRADE AND ECONOMICS ІII, n. 91 (30 ottobre 2023): 173–84. http://dx.doi.org/10.34025/2310-8185-2023-3.91.12.

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Abstract (sommario):
In connection with the continuation of military operations in the country, the increase in the number of enlisted men for military service and the complicated consequences that arise during return of the defenders to peaceful life, the rehabilitation of servicemen is urgent. The purpose of the study is to substantiate and develop practical recommendations for the provision of rehabilitation services for recovery of the military personnel in hotel enterprises. The research methodology was based on general scientific methods: analysis, synthesis, classification and review-analytical method, as well as the study of scientific literature on the research topic. The definition of the concept of rehabilitation is formulated and both traditional and modern methods of rehabilitation are considered. A study of the existing rehabilitation centers for conscripts operating on the territory of Ukraine was conducted. Taking into account that the armed aggression of the Russian Federation continues, we see the need to open new enterprises and introduce rehabilitation services against the background of health resorts and resort hotels. The Western part of the country is a promising location for such institutions, due to its favorable climate, clean air and incredible landscapes. The basic requirements and standards for the establishment of a hotel enterprise with a military rehabilitation center are outlined, for proper recovery conditions and a positive emotional impact on the defenders of our country. The design or reconstruction of hotel enterprises with centers for rehabilitation of the military personnel will have a positive impact not only directly on the defenders of Ukraine, but will also affect the economy of the state, its social and humanitarian spheres as a whole. The authors define perspective of the further research in a scientific search for the most "efficiently working" recovery methods for military personnel and to determine the services that will be offered by the rehabilitation center at the hotel enterprise.
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Takahashi, Mono, Yasumi Katayama, Hironobu Takada, Chichun Lin e Hajime Kuwayama. "Continuation of acid suppression therapy by rabe-prazole after successful Helicobacter pylori eradication accelerates peptic ulcer healing: Single-center prospective randamized control study". Gastroenterology 118, n. 4 (aprile 2000): A1312. http://dx.doi.org/10.1016/s0016-5085(00)81108-7.

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Lam, L. D., L. Czer, C. Runyan, I. Otarola, J. Jang, J. Lau, M. Gau et al. "Outcome of Enoxaparin Bridging in Left Ventricular Assist Devices (LVAD) in an Ambulatory Setting: A Continuation Study at Cedars Sinai Medical Center (CSMC)". Journal of Heart and Lung Transplantation 42, n. 4 (aprile 2023): S501. http://dx.doi.org/10.1016/j.healun.2023.02.1380.

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Abou Jaoude, Maya, Sara Moukarzel, Stef P. J. Kremers e Jessica S. Gubbels. "Factors Related to Breastfeeding Support in Lebanese Daycare Centers: A Qualitative Study among Daycare Directors and Employees". International Journal of Environmental Research and Public Health 18, n. 12 (8 giugno 2021): 6205. http://dx.doi.org/10.3390/ijerph18126205.

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Breastfeeding has an important impact on maternal and child health, and is affected by several factors influencing its initiation and continuation. This qualitative study aimed to assess the main promoting and hindering factors for breastfeeding support in Lebanese daycare centers (DCCs), through the perspective of their directors and employees. The study was based on semi-structured interviews with 13 directors and 9 employees. It explored the influence of various cognitive factors as well as different environment types (physical, economic, political, and sociocultural) on their breastfeeding support. Findings suggested the directors and employees valued improving breastfeeding support in DCCs and the physical set-up of the DCCs allowed for this. However, various other factors restricted their abilities to support breastfeeding in the DCC, including limited knowledge and training on the topic, absence of written internal policies on breastfeeding, lack of enforcement in the application of national policies, and the current mothers’ work policies that negatively influenced the decision to breastfeed. Improvements could be achieved through integrated interventions, targeting the interaction of internal DCCs factors and national and DCCs breastfeeding policies, as well as several social factors, to create a multilevel approach targeting breastfeeding continuation support in breastfeeding-friendly DCCs in Lebanon and the region.
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Modjo, Mohamad-Ikhsan, e Agus-Supriatna Wibowo. "Pricing Strategy for a Smart-Tourist Area: Does Location Matters?" E3S Web of Conferences 426 (2023): 02061. http://dx.doi.org/10.1051/e3sconf/202342602061.

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This study aims to investigate the effect of hotel characteristics, particularly their locations, on room pricing strategy for hotels in the Bogor Area, Indonesia. The author applies the quantile hedonic regression model on a dataset of Bogor Hotels collected through a travel agent’s website. A total of 194 hotels were collected and used as data samples. Our findings suggest that locations near tourist attractions are a significant factor in explaining hotel room prices in the Bogor area, while in contrast, the city center location is not. In addition, we also find that hotel room size and stars-awarded have significant positive effects on room rates. The outcomes of this study advocate for the continuation of fine-tuning the existing pricing strategy adopted by hoteliers to optimize revenue.
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