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Libri sul tema "Cartes – Normes"

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Autore: Grafiati
Pubblicato: 1 giugno 2024

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1

Bhargav, Abhay. PCI compliance: The definitive guide. Boca Raton: CRC Press, 2014.

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2

López, Andrés López. El cartel de los sapos. Bogotá: Editorial Planeta Colombiana, 2008.

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3

Gurrieri, Francesco. Restauro e conservazione: Carte del restauro, norme, convenzioni e mozioni sul patrimonio architettonico ed artistico. Firenze: Edizioni Polistampa, 1992.

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4

Torsten, Hägerstrand, e Buttimer Anne, a cura di. Geographers of Norden: Reflections on career experiences. Lund, Sweden: Royal University of Lund, Dept. of Geography, Lund University Press, 1988.

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5

López, Andrés López. El cartel de los sapos 2. Doral, FL: Aguilar, 2010.

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6

Campeis, Giuseppe. Carte e corti europee diritti fondamentali e giustizia italiana: L'operatore nazionale fra norme paracostituzionali e sentenze normative europee nella stravolta gerarchia delle fonti. Torino: G. Giappichelli Editore, 2014.

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7

Nosella, Paolo. Schola Mater: A antiga Escola Normal de São Carlos, 1911-1933. São Carlos: Editora da UFSCar, 1996.

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8

Robinson, Jeffrey. The takedown: A suburban mom, a coal miner's son, and the unlikely demise of Colombia's brutal Norte Valle Cartel. New York: Thomas Dunne Books, 2011.

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9

Enterline, James Robert. Erikson, Eskimos & Columbus: Medieval European knowledge of America. Baltimore: Johns Hopkins University Press, 2002.

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10

Piccardo, Nicoletta. Estrategias para hacer carrera. Barcelona: Editorial De Vecchi, 1992.

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11

Piccardo, Nicoletta. Cómo conseguir el éxito profesional. Barcelona: Editorial De Vecchi, 1997.

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12

Psychiatrists, Royal College of. Good psychiatric practice: CPD. London: Royal Colege of Psychiatrists, 2001.

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13

Williams, William Carlos. The American idiom: A correspondence. San Francisco, CA: Bright Tyger Press, 1990.

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14

Carlos, Williams William. The American idiom: A correspondence. San Francisco, CA: Bright Tyger Press, 1990.

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15

Murphy, Margueritte S. A tradition of subversion: The prose poem in English from Wilde to Ashbery. Amherst: University of Massachusetts Press, 1992.

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16

Classification des pesticides à l'aide de cartes auto-organisatrices de Kohonen en vue du développement de normes de performance agro-environnementale atteignables (NPA) à l'échelle des bassins versants. Québec: Centre Eau, terre et environnement, Institut national de la recherche scientifique, 2007.

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17

Kaarten van de chemische kwaliteit van de waterlopen in Belgie voor 1986-1987 (Basiliskwaliteitsnormen)/Cartes de la qualite des eaux superficielles belges en 1986-1987 (Normes de qualite de base). Brussels/Bruxelles: s.n., 1986.

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18

Bhargav, Abhay. PCI Compliance: The Definitive Guide. Auerbach Publishers, Incorporated, 2014.

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19

Bhargav, Abhay. PCI Compliance: The Definitive Guide. Taylor & Francis Group, 2014.

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20

Elsdon, Ron. How to Build a Nontraditional Career Path. ABC-CLIO, LLC, 2014. http://dx.doi.org/10.5040/9798400666773.

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Abstract (sommario):
An invaluable resource for general readers at any career stage, this book explains why, when, and how to engage in a fulfilling, nontraditional career path that is both inspiring and practical. The paradigm of the successful career has shifted. No longer is working for a single company or even within a single career field throughout one's lifetime the norm. Today, many people are considering nontraditional paths to achieving success. How to Build a Nontraditional Career Path: Embracing Economic Disruption explains what such a career path looks like and details the benefits and challenges of pursuing this option. Author Ron Elsdon identifies the types of individuals who will likely find nontraditional careers attractive and examines critical strategic issues, thereby enabling the reader to assess whether and how such a path might fit their personality, life goals, and career objectives. The information presented will benefit those considering "something different" at their entry to the workforce, individuals in middle or later career stages re-assessing their direction, people re-engaging with a career at an encore stage, or those whose previous career paths have been disrupted by an external event such as job loss.
21

Ballard, John. Decoding the Workplace. ABC-CLIO, LLC, 2015. http://dx.doi.org/10.5040/9798400638664.

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Abstract (sommario):
This highly readable career development book reveals dynamic aspects of the workplace that are hidden to many, ignored by others�factors that can make or break careers. There are many key questions about work that most individuals never consider. How can workplace norms affect our careers in powerful ways? How do sex-role stereotypes impact our behaviors? When are "teams" not teams? How does organizational culture profoundly affect your workplace? What questions should you ask yourself about your boss? What factors most affect job satisfaction and success? Decoding the Workplace: 50 Keys to Understanding People in Organizations is a must-read for anyone wanting to better understand the workplace and become more effective and successful. Written by a former management consultant to the U.S. Air Force and a professor and organizational behavior scholar, this definitive work explains many of the dynamics at play in our organizations. Beyond being informative, insightful, and beneficial to any employee, regardless of job status or experience, it is highly readable, entertaining, and thought-provoking.
22

Isherwood, Lisa. Lesbians. A cura di Adrian Thatcher. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199664153.013.017.

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This essay is situated within the sexual theologies discipline—that is, it will not consider what theology has said about lesbians. It will rather engage with what lesbian experience has offered traditional Christian theology. Perhaps this can be best summed up in the words of Carter Heyward who wrote ‘To say “I love you” means—Let the revolution begin!’ Once lesbians in theology found a voice, what we witness is indeed a revolution as the diverse face of the divine began to emerge from what had been a ‘one size fits all’ theology in matters of sexuality and ethics. Far from simply stating that the norm did not fit all sexualities and genders, many lesbian theologians moved on to say that the norm did not even do justice to those seen as normal and that the heteronormative underpinnings of theology actually crippled it.
23

Kelly, Gillian. Tyrone Power. Edinburgh University Press, 2021. http://dx.doi.org/10.3366/edinburgh/9781474452946.001.0001.

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One of the most popular actors of the Classical Hollywood period, Tyrone Power’s appeal was initially based around his outstanding beauty, his looks remaining key to his star persona throughout his 25-year career and almost 50 films, most of which were made at Twentieth Century-Fox, before his untimely death in 1958 at the age of 44. Although Power was one of Classical Hollywood’s major stars of the pre- and post-war years, he remains academically neglected. This book presents the first substantial academic study of Power and employs a range of approaches, including stardom and genre theory, to reappraise his career from various angles including gender, genre and image. Textual analysis coincides with discussions of Power’s multi-layered performances in a variety of genres while engaging with industry systems, specifically Twentieth Century-Fox, his home studio for almost two decades, and situates Power’s performances within the contexts of industry regulations, such as the Production Code, and industry technological advances, such as CinemaScope. A key historical figure of American cinema, Power’s significant career trajectory from pretty boy ‘pin-up’ in the 1930s to mature, virile action-adventure star at the close of his career demonstrates the natural progression of a ‘normal’ life and his ability to remain relevant across the decades. This book is part of a welcome new wave of scholarly studies on overlooked stars, such as Power, whose careers were initially based around their looks but who maintained a career as they aged.
24

Enterline, James Robert. Erikson, Eskimos, and Columbus: Medieval European Knowledge of America. The Johns Hopkins University Press, 2004.

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25

Enterline, James Robert. Erikson, Eskimos, and Columbus: Medieval European Knowledge of America. Johns Hopkins University Press, 2003.

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26

Scholz, Imme, Lilian Busse e Thomas Fues, a cura di. Transboundary Cooperation and Global Governance for Inclusive Sustainable Development. Nomos Verlagsgesellschaft mbH & Co. KG, 2022. http://dx.doi.org/10.5771/9783748930099.

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This book gathers renowned researchers and policymakers from all continents who have accompanied Dirk Messner’s professional life in science and policy advice. Their articles and essays cover topics related to the ideational spheres and practice-oriented spaces which have consistently characterised Dirk Messner’s career. These include steps at the national, regional or global level to effectively accelerate the shift towards planetary sustainability; measures to forge or strengthen cross-sectoral, transboundary, multi-actor alliances for sustainable transformation; and key elements of universal ethics and shared norms which foster transnational cooperation for the global common good. With contributions by Manish Bapna, Lilian Busse, Ani Dasgupta, J. Carlos Domínguez, Ottmar Edenhofer, Jörg Faust, Thomas Fues, Hans Haake, Medelina K. Hendytio, Ariel Macaspac ­Hernandez, Anna-Katharina Hornidge, Adolf Kloke-Lesch, Claus Leggewie, Siddharth Mallavarapu, Simon Maxwell, Dirk Meyer, Nebojsa Nakicenovic, Sabine Nallinger, Andrew Norton, Franz Nuscheler, Jiahua Pan Jürgen Renn, Enrique ­Saravia, Sabine Schlacke, Uwe Schneidewind, Imme Scholz, Svenja Schulze, Zita Sebesvari, Wolfgang Seidel, Elizabeth Sidiropoulos, Achim Steiner, Franziska Wehinger and ­Heidemarie Wieczorek-Zeul.
27

Whitmire, Ethelene. Normal, Illinois; Chicago; Wilberforce; and Chicago Public Library. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252038501.003.0003.

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This chapter details Regina's years in Normal, Illinois; and then shifts to her return to Chicago and her college experiences at Wilberforce University. It was in Normal that she attended school with the future Illinois governor and presidential candidate Adlai Stevenson II. In terms of her experiences in Normal, Regina later credited an understanding librarian as a guiding influence in her early life and training which has brought success in her chosen field. Meanwhile, Regina's experiences at the Chicago Public Library were mostly negative. However, she later said she was influenced by Vivian G. Harsh—Chicago Public Library's head librarian. The current Vivian G. Harsh Collection of Afro-American History and Literature at the Carter G. Woodson Regional Library is named after her.
28

Finney, Gladys Turner. Joseph Carter Corbin: Educator Extraordinaire and Founder of the University of Arkansas at Pine Bluff. Butler Center for Arkansas Studies, 2017.

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29

Hamilton, Sam C., e Nathalie Beullens-Maoui. Misión de San Carlos Borroméo Del Río Carmelo (Discovering Mission San Carlos Borromeo Del Río Carmelo). Cavendish Square Publishing LLC, 2015.

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30

Hamilton, Sam C., e Nathalie Beullens-Maoui. Misión de San Carlos Borroméo Del Río Carmelo (Discovering Mission San Carlos Borromeo Del Río Carmelo). Cavendish Square Publishing LLC, 2015.

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31

Hamilton, Sam C., e Nathalie Beullens-Maoui. Misión de San Carlos Borroméo Del Río Carmelo (Discovering Mission San Carlos Borromeo Del Río Carmelo). Cavendish Square Publishing LLC, 2015.

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32

Kapitan, Katarzyna Anna, Helen F. Leslie-Jacobsen, Luke John Murphy, Simon Nygaard e Beth Rogers. Selected Presentations from the Network of Early Career Researchers in Old Norse (2017-2019). Aahus University Library, 2020. http://dx.doi.org/10.7146/aul.390.

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33

Lee, A. Robert, e Douglas Field, a cura di. Harold Norse. Liverpool University Press, 2022. http://dx.doi.org/10.3828/liverpool/9781638040163.001.0001.

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Abstract (sommario):
Despite publishing over a dozen collections of poetry, many off which were critically acclaimed, Harold Norse remains an outsider, a poet who is known to aficionados of post-World War II poetry, to students of Gay Liberation poetry, and to scholars of the Beat Generation. Norse has been overlooked by scholars of mid-twentieth century poetry, as well as being conspicuously absent from major poetry anthologies. Harold Norse: Poet Maverick, Gay Laureate, the first book-length study of this writer, explores his work and legacy across the Beats, The Living Theatre, the Mimeograph Revolution, as well as his fellow travelers, among them William Carlos Williams, Allen Ginsberg, and Charles Bukowski.
34

Zetterberg, Pär. Women’s Conditioned Access to Political Office in Mexico. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190851224.003.0011.

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Pär Zetterberg points out that whereas women’s legislative representation at the national and subnational level in Mexico has increased dramatically and they have gained nearly 1/3 of seats on party executive bodies, women have done poorly in executive offices. Much of this results from Mexican rules and norms that prioritize long-standing male party backbenchers’ political careers. These challenges persist when examining the institutional consequences of women’s presence in office. Women have to walk a fine line between representing women and responding to formal and informal institutional incentives to protect their own political careers. This has resulted, Zetterberg argues, in a clear gendered division of labor in Mexican politics. Zetterberg highlights that greater democratization and more inclusive formal and informal rules are necessary to change the gendered nature of Mexico’s political system and further incorporate women.
35

Iturburu Salvador, Daniel Douglas, e Julio Cesar Castro Rosado. Estudio de la vulnerabilidad sísmica de los edificios de Guayaquil. Editorial Tecnocientífica Americana, 2021. http://dx.doi.org/10.51736/eta2021ci1.

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La mayoría de los edificios que se encuentran en Guayaquil no cumplen con las normas vigentes por el Código Ecuatoriano de la Construcción (NEC 2015). Por esa razón, este libro profundiza en el estudio del comportamiento del bloque (B) del Colegio Vicente Rocafuerte ante la aplicación de cargas horizontales, lo que determina la capacidad de la estructura como está. Posteriormente, se expone un análisis no lineal de la estructura, que tiene como fin determinar con certeza los daños que sufriría al ser sometida a los sismos esperados en la ciudad de Guayaquil. Este estudio permite establecer cuál es la mejor propuesta de reforzamiento para que la estructura tenga una sólida resistencia ante sismos esperados.
36

Clark, Roger S. William Schabas. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190272654.003.0001.

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The introduction by Roger Clark presents the early life of William Schabas, and some of the influences that must have shaped his career. It offers in Section II of this portrait some ruminations about his thoughts and interests based on a reading of his 2012 book Unimaginable Atrocities: Justice, Politics and Rights at the War Crimes Tribunals. This work is a set of reflections about many of his academic journeys, a kind of memoir but without the normal chronological trappings and personal puffery of the genre. It is perhaps the most opinionated of his oeuvre. It paints with a broader brush than much of his work. It is also this book that has the least trappings of scholarship, that is to say it lacks the copious footnotes that are his normal hallmark.
37

Trifu, Arina Cipriana. Fenomenul Hikikomori. De la sindrom la boală clinica. Editura Universitara, 2021. http://dx.doi.org/10.5682/9786062813291.

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Fenomenul Hikikomori este raspandit in societatea moderna. Disimulat, argumentat, ”ascuns” sau ”investmantat” in alte cuvinte cu semnificatie mai putin patologica, el este o realitate a zilelor noastre. Pentru psihiatri occidentali este o realitate clinica. Pentru psihiatria estica - o realitate existentiala. Ca si anxietatea, care variaza de-a lungul unei vaste pleiade, intre aspectele sale sociale si cele situate la extrema angoaselor destructurante. Cartea de fata baleiaza plaja suferintei acestor tineri de la introversiune, izolare sociala, construirea unei lumi proprii cu reguli, norme si bucurii particulare la depresivitate, alexitimie, absenta oricarei dorinte de a-si gasi senzatii de plenitudine. Viata capata noi sensuri, cu refugiu in idealizari - uneori infantile, alteori de absenteism sufletesc si moral - identitate difuza. Cand disolutia Eului conduce la contopirea cu universul, cand fenomenologia negativa se amplifica sau pulsiunile bulimice iau forme ce afecteaza corporalitatea - in incercarea de autoprotectie -, ne apropiem de diagnostice psihiatrice variate, in varii taxonomii.
38

Piccardo, Nicoletta. Estrategias Para Hacer Carrera. de Vecchi, 1995.

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39

Piccardo, Nicoletta. Estrategias para Hacer Carrera. De Vecchi, Editorial, S.A., 2022.

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40

Miller, Christopher. Planning and Profits. Liverpool University Press, 2018. http://dx.doi.org/10.5949/liverpool/9781786940667.001.0001.

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Abstract (sommario):
In a time of great need for Britain, a small coterie of influential businessmen gained access to secret information on industrial mobilisation as advisers to the Principal Supply Officers Committee. They provided the state with priceless advice, but, as “insiders” utilised their access to information to build a business empire at a fraction of the normal costs. Outsiders, in contrast, lacked influence and were forced together into a defensive “ring” – or cartel – which effectively fixed prices for British warships. By the 1930s, the cartel grew into one of the most sophisticated profiteering groups of its day. This book examines the relationship between the private naval armaments industry, businessmen, and the British government defence planners between the wars. It reassesses the concept of the military-industrial complex through the impact of disarmament upon private industry, the role of leading industrialists in supply and procurement policy, and the successes and failings of government organisation. It blends together political, naval, and business history in new ways, and, by situating the business activities of industrialists alongside their work as government advisors, sheds new light on the operation of the British state. This is the story of how these men profited while effectively saving the National Government from itself.
41

Chung, Heejung. The Flexibility Paradox. Policy Press, 2022. http://dx.doi.org/10.1332/policypress/9781447354772.001.0001.

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Throughout the COVID-19 pandemic, flexible working has become the norm for many workers. However, does flexible working really provide a better work-life balance, enhance worker’s well-being and gender equality? This volume offers an original examination of flexible working using data from 30 European countries and drawing on studies conducted across the world including China, the US and India. The book reveals how flexible working can lead to workers working longer and harder, with work encroaching on family life. This is largely due to our current work and work-life balance culture, where long hours work in the office is hailed as the ideal productive worker, compounded by the decline in workers’ bargaining power and increased levels of insecurities. Similarly, norms around gender roles and intensive parenting cultures shape how the patterns of exploitation manifests differently for women and men. Women end up exploiting themselves at home by increasing time spent on childcare and housework, reenforcing traditional gender roles. This, and assumptions around women’s flexible working can explain why women and mothers may especially be party to negative career consequences when working flexibly. However, all is not lost. The book shows changes in cultural and institutional contexts, and the wide-spread of flexible working can help change the patterns of flexibility paradox. Taking a critical stance, this book investigates the potential risks and benefits of flexible working and provides crucial policy recommendations for policy makers, managers, and workers alike in overcoming the negative consequences.
42

Curry, Jane K. Nineteenth-Century American Women Theatre Managers. Greenwood Publishing Group, Inc., 1994. http://dx.doi.org/10.5040/9798400691683.

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Many women held positions of great responsibility and power in the United States during the 19th century as theatre managers: managing stock companies, owning or leasing theatres, hiring actors and other personnel, selecting plays for production, directing rehearsals, supervising all production details, and promoting their dramatic offerings. Competing in risky business ventures, these women were remarkable for defying societal norms that restricted career opportunities for women. The activities of more than 50 such women are discussed in Nineteenth-Century American Women Theatre Managers, beginning with an account of 15 pioneering women managers who were all managing theatres before 24 December 1853, when Catherine Sinclair, often incorrectly identified as the first woman theatre manager in the United States, opened her theatre in San Francisco.
43

Conrad, Ruth, Roland Hardenberg, Hanna Miethner e Max Stille, a cura di. Ritual and Social Dynamics in Christian and Islamic Preaching. Bloomsbury Publishing Plc, 2024. http://dx.doi.org/10.5040/9781350408876.

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Christian and Islamic sermons from past and present, and their preachers, are analyzed to reveal the socio-cultural dynamics of religious speeches. Part I focuses on the explicit contribution of sermons in socio-cultural transformation processes. It shows how sermons connect with holy texts, religious norms of the specific group, and social-cultural contexts. Part II analyzes the dynamic tension between normativity and popularity. Rather than juxtaposing normative stances and the popularity of sermons, it shows how that normativity can itself contribute to popularity and the quest of popularity carries its own normative stances. Part III explores the ritual embeddedness of religious speech in the sermon in relation to social dynamics, normativity, and popularity, and shows how speech and rituals have a reciprocal relationship.
44

Winkler, Emily A. Introduction. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198812388.003.0001.

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Chapter 1 introduces the core argument of the book, which is that twelfth-century writers of history in England accorded more individual responsibility, both causal and moral, to eleventh-century English kings than did their historical sources. In their conquest narratives, the four historians redistribute responsibility away from the English as a collective, revealing proportionally high expectations for English kings. This change, which occurs across the four historians’ diverse genres of writing, arose from their wide reading, experience with Anglo-Norman rule, and the precedents for foreign kings of England set by the Danish and Norman Conquests of the eleventh century. The chapter examines the nature of explanation in twelfth-century historical narratives (including the role of fortune and Providence), outlines the careers of the four writers (William of Malmesbury, Henry of Huntingdon, John of Worcester, and Geffrei Gaimar), and provides an overview of each writer’s approach to narrating the English past.
45

Ebeling, Jennie, e Philippe Guillaume, a cura di. The Woman in the Pith Helmet. Lockwood Press, 2020. http://dx.doi.org/10.5913/2020334.

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This volume celebrates the career of Norma Franklin, an archaeologist who has made important contributions to our understanding of the three key cities of Samaria, Megiddo, and Jezreel in the Northern Kingdom of Israel during the Iron Age. The sixteen essays offered herein by Franklin’s colleagues in archaeology and biblical studies are a fitting tribute to the woman in the pith helmet: an indomitable field archaeologist who describes herself as “happiest with complex stratigraphy” and dedicated to “killing sacred cows.”
46

McKinlay Gardner, R. J., e David J. Amor. Robertsonian Translocations. A cura di R. J. McKinlay Gardner e David J. Amor. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199329007.003.0007.

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Abstract (sommario):
Robertsonian translocations are among the most common balanced structural rearrangements seen in the general population, with a frequency in newborn surveys of about 1 in 1,000. Robertsonian translocations have their own peculiar characteristics and need to be considered separately. These translocations arise from fusions between different acrocentric chromosomes (heterologous Robertsonian translocation) or, rather rarely, between the same chromosome (homologous Robertsonian translocation). The imbalances which may be seen in gametes/offspring of carriers are either pure aneuploidies, or full uniparental disomies. There is also an association with male infertility. This chapter considers the case of the phenotypically normal person who carries, in balanced form, a Robertsonian translocation.
47

Sterne, Jonathan. Diminished Faculties. Duke University Press, 2021. http://dx.doi.org/10.1215/9781478022329.

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Abstract (sommario):
In Diminished Faculties Jonathan Sterne offers a sweeping cultural study and theorization of impairment. Drawing on his personal history with thyroid cancer and a paralyzed vocal cord, Sterne undertakes a political phenomenology of impairment in which experience is understood from the standpoint of a subject that is not fully able to account for itself. He conceives of impairment as a fundamental dimension of human experience, examining it as both political and physical. While some impairments are enshrined as normal in international standards, others are treated as causes or effects of illness or disability. Alongside his fractured account of experience, Sterne provides a tour of alternative vocal technologies and practices; a study of “normal” hearing loss as a cultural practice rather than a medical problem; and an intertwined history and phenomenology of fatigue that follows the concept as it careens from people to materials science to industrial management to spoons. Sterne demonstrates how impairment is a problem, opportunity, and occasion for approaching larger questions about disability, subjectivity, power, technology, and experience in new ways. Diminished Faculties ends with a practical user’s guide to impairment theory.
48

Berrettini, Mark L. Efficiency, Estrangement, and Antirealism. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252035951.003.0001.

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Abstract (sommario):
This chapter presents a commentary on Hal Hartley's film career. It begins with a biographical sketch based on material included in interviews, reviews, and essays about Hartley's work, and an earlier version of his official website, possiblefilms.com. It then moves on to analyze seven feature films: The Unbelievable Truth (1989), Trust (1990), Simple Men (1992), Amateur (1994), Henry Fool, Fay Grim (2006), and The Book of Life (1998). These films show that efficiency, estrangement, and antirealism allow Hartley to chart the struggles of individuals against the ideological precepts that pertain to public and private behavior, responsible actions, “common sense,” and the cinematic conventions that support such ideologies. (e.g., romantic characters who will live “happily ever after”).These conflicts are often related to the restrictions posed by gender norms and are depicted as conflicts with authority figures. Hartley's male protagonists struggle to live up to popular ideals of heteronormative masculinity, control, and violent mastery of the world around them, while his central female characters break from heteronormative conceptions of women as mothers, caregivers, and/or sexual objects.
49

Zuccato, Chiara, e Elena Cattaneo. Normal Function of Huntingtin. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0011.

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Abstract (sommario):
Huntingtin (HTT) is the 3,144–amino acid protein product of the Huntington’s disease gene (HTT), which can be traced back through 800 million years of evolution. It carries a trinucleotide CAG repeat that encodes polyglutamine (polyQ) at an evolutionarily conserved NH2-terminal position in exon 1. This chapter discusses the discoveries that have mapped the evolutionary history of HTT and the CAG repeat and the critical role of the protein in development as well as its activities in the adult brain. During embryogenesis, HTT is critical for gastrulation, neurulation, and neurogenesis. In the adult brain, HTT acts as an antiapoptotic protein and promotes transcription of neuronal genes and vesicle transport. Subversion or exacerbation of HTT brain function by an abnormally expanded polyQ repeat contributes to neuronal vulnerability in HD and suggests that loss of normal HTT function may be implicated in the disease.
50

Chanmugam, Arjun S., e Gino Scalabrini. Urinary Tract Infections in Women. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199976805.003.0037.

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Urinary tract infections (UTIs) refer to a urine culture yielding a minimum of 100 to 10,000 bacteria units/mm of urine usually from a clean catch midstream sample. This can result from infection of the lower urinary tract involving the bladder (cystitis) or an infection of the upper urinary tract involving the kidneys (pyelonephritis). Uncomplicated UTIs occur in healthy, pre-menopausal, non-pregnant women with a normal urinary tract who have a high likelihood to respond favorably to treatment, but consider local antibiotic resistance patterns. Complicated UTIs occur in women with coexisting pathology, anatomical abnormality, underlying comorbidity, or immunocompromise. Untreated UTIs can progress to pyelonephritis and urosepsis. Asymptomatic bacteriuria for pregnant women can progress very quickly; pyelonephritis carries increased risk of perinatal and neonatal mortality. Pregnant patients should be treated with cephalexin, amoxicillin, or amoxicillin-clavulanic acid (avoiding fluoroquinolones).
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