Articoli di riviste: "Cardiopathies – Diagnostic"

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NCHO MOTTOH Marie-Paule Berdanette, GARBA Idrissa, N’GORAN Yves, ANGORAN Ines, AVOH Ami, DOH Cédric, ALLEKE Samuel Koffi e COULIBALY Ali. "SCANNER CARDIAQUE PEDIATRIQUE DANS LE DIAGNOSTIC DES CARDIOPATHIES CONGENITALES: EXPERIENCE ABIDJANAISE". Journal Africain d Imagerie Médicale (J Afr Imag Méd) Journal Officiel de la Société de Radiologie d’Afrique Noire Francophone (SRANF) 16, n. 1 (10 maggio 2024): 10–16. http://dx.doi.org/10.55715/jaim.v16i1.442.

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Depuis 2008, la Haute Autorité Sanitaire recommande la réalisation du scanner cardiaque dans le diagnostic des cardiopathies congénitales. Celui-ci aide à confirmer et préciser les anomalies mal définies à l’échocardiographie. Dans les pays développés, le scanner cardiaque est un examen de routine pour le diagnostic des cardiopathies congénitales. En Côte-d’Ivoire, sa pratique est récente. L’objectif de cette étude était de décrire les techniques et résultats des scanners cardiaques pédiatriques réalisés dans une structure privée à Abidjan. Il s’agissait d’une étude descriptive rétrospective sur une période de 2 mois qui a inclus tous les enfants reçus à la clinique la rosette pour la réalisation d’un scanner cardiaque indiqué pour l’évaluation d’une cardiopathie congénitale. Les examens ont été réalisés sous sédation légère pour les enfants de moins de 7 ans. Vingt scanners cardiaques pédiatriques ont été réalisés. Les indications des scanners cardiaques pédiatriques étaient la tétralogie de Fallot (15 cas), l’atrésie pulmonaire à septum ouvert (APSO) (2 cas), la communication interauriculaire (CIA) (1 cas), la CIA associée à une communication interventriculaire (CIV) (1 cas) et la sténose pulmonaire supravalvulaire (1 cas). Dans les cas de Tétralogie de Fallot et d’APSO, les branches pulmonaires et les collatérales aorto-pulmonaires ont été visualisées et mesurées. Pour le bilan de la CIA, un retour veineux pulmonaire non visualisé à l’échocardiographie a été retrouvé au scanner cardiaque. Dans tous les cas, un bilan tomodensitométrique malformatif était réalisé : recherche d’anomalies coronaires et d’arcs aortiques. Après réalisation du scanner cardiaque, 5 enfants ont bénéficié d’une cure chirurgicale. On notait une concordance entre les diagnostics per-opératoires et tomodensitométriques. Dans notre expérience, le scanner cardiaque représente désormais un outil diagnostique complémentaire important, fiable, peu invasif, pour l’évaluation des cardiopathies congénitales.

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CHETBOUL, V., e J. POUCHELON. "Diagnostic échodoppler des cardiopathies congénitales". EMC - Vétérinaire 1, n. 5 (ottobre 2004): 175–90. http://dx.doi.org/10.1016/s1762-4215(04)00019-x.

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Le Bidois, J. "diagnostic anténatal des cardiopathies complexes". Journal de Pédiatrie et de Puériculture 15, n. 2 (marzo 2002): 82–83. http://dx.doi.org/10.1016/s0987-7983(02)83023-7.

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Bonnet, D. "Le diagnostic prénatal des cardiopathies congénitales". Archives de Pédiatrie 16, n. 6 (giugno 2009): 625–27. http://dx.doi.org/10.1016/s0929-693x(09)74091-6.

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Eyrolle, D., e R. Nguyen. "Diagnostic DES cardiopathies congenitales en polynesie Francaise". European Journal of Ultrasound 7 (febbraio 1998): S1. http://dx.doi.org/10.1016/s0929-8266(97)80103-6.

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de Araújo Bueno Neto, Antenor, Yan Augusto Gomes Silva, Jacqueline Satomi Tho, Camila Gasparotto Fernandes, Felipe Gazza Romão, Beatriz Perez Floriano e Luciene Maria Martinello Romão. "Retrospective study of the prevalence of heart diseases in dogs". Clínica Veterinária XXII, n. 129 (1 luglio 2017): 46–54. http://dx.doi.org/10.46958/rcv.2017.xxii.n.129.p.46-54.

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This work aimed to analyze the frequency of the main cardiopathies in dogs treated in the region of Bauru, SP, Brazil. A population of 466 dogs (285 females and 181 males) referred to a veterinary cardiology center from January 1st, 2014 to July 31st, 2015 was evaluated by echocardiographic examination. Factors such as race, age and sex were considered. Valvular disease was the most prevalent heart condition, followed by pulmonary hypertension. The increase in complementary diagnostic methods in the clinical practice has increased the possibility of diagnosis of cardiopathies in veterinary medicine.

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Vecht, R. J. "Le Diagnostic des Cardiopathies par le Catheterisme et l'Angiocardiographie". Postgraduate Medical Journal 63, n. 744 (1 ottobre 1987): 922. http://dx.doi.org/10.1136/pgmj.63.744.922-b.

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Vial, Yvan, Nicole Sekarski, Stefano Di Bernardo, Yvan Mivelaz, Erik Meijboom, Michel Hurni e Ludwig von Segesser. "Pédiatrie Avantages du diagnostic prénatal dans les cardiopathies congénitales". Revue Médicale Suisse 1, n. 2 (2005): 148–52. http://dx.doi.org/10.53738/revmed.2005.1.2.0148.

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Luca, Alina-Costina, Andreea-Simona Holoc, Mirabela Subotnicu e Constantin Iordache. "CLINIC AND THERAPEUTIC ASPECTS IN DUCTUS-DEPENDENT CONGENITAL HEART DEFECTS (PART II)". Romanian Journal of Pediatrics 64, n. 3 (30 settembre 2015): 246–51. http://dx.doi.org/10.37897/rjp.2015.3.2.

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The cardiac congenital malformations with duct dependent pulmonary circulation are cardiopathies with severe neonatal manifestations and quickly progressive hemodynamic degradation. The obvious semeiology at the birth requires an appropriate diagnostic and an early therapeutic management through the maintenance of the arterial channel permeability.

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Kane, Bourama, e Et Al. "Des abcès cérébraux révélateurs d’un ventricule droit à double issue chez un enfant de 5 ans dans le service de pédiatrie de l’Hôpital du Mali". Revue Malienne d'Infectiologie et de Microbiologie 17, n. 1 (30 aprile 2022): 54–60. http://dx.doi.org/10.53597/remim.v17i1.2227.

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Introduction Les abcès cérébraux sont des collections suppurées intra crâniennes graves et rares chez l’enfant. Les auteurs rapportent un cas d’abcès cérébraux compliquant une cardiopathie congéniatale à type de ventricule droit à double issue chez un enfant de 5 ans pris en charge à l’Hôpital du Mali et au Centre Cardio-Pédiatrique « André FESTOC » de l’Hôpital Mère Enfant « le Luxembourg ». Observation Il s’agissait d’un garçon de 5 ans aux antécédents de dyspnée et de retard staturo-pondéral admis pour hémiplégie gauche. Un scanner cérébral a révélé de multiples abcès cérébraux. L’échographie cardiaque demandée dans le cadre du bilan étiologique a montré une tétralogie de Fallot. Un drainage chirurgical associé à un traitement par valproate de sodium ( 10 mg/kgs/12heures en IVL), ceftriaxone (100 mg/kgs/j une fois en IVD), metronidazole ( 10 mg/kgs/12heures en IVL pendant 15 jours), gentamycine ( 3 mg/kgs/j en IVL une fois pendant 3jours et la kinésithérapie motrice. Le relai a été pris par la voie orale avec la ciprofloxacine, le metronidazole pendant 1 mois et le valproate de sodium pendant 24 mois. Les suites opératoires ont été simples avec une amélioration progressive de l’hémiplégie et une persistance de l’hypoxie. La prise en charge de lacardiopathie a été faite 3 ans après. Les chirugiens ont découvert un ventricule droit à double issue lors de cette prise en charge. Conclusion : L’abcès du cerveau est une complication grave et tardive des cardiopathies congénitales. Le scanner cérébral indispensable au diagnostic doit être systématique dans les déficits moteurs des enfants souffrant de cardiopathies congénitales pour ne pas passer à côté de cette complication

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Ruiz-Tovar, Jaime, Vicente Morales, Alfonso Sanjuanbenito, Eduardo Lobo e Enrique Martinez-Molina. "Volvulus of the Small Bowel in Adults". American Surgeon 75, n. 12 (dicembre 2009): 1179–82. http://dx.doi.org/10.1177/000313480907501206.

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The volvulus of the small bowel is a surgical emergency, causing small bowel obstruction. We performed a retrospective study of all the patients diagnosed and treated with small bowel volvulus between 1977 and 2007 at our institution. One hundred twenty-nine patients were analyzed. Thirty-nine patients presented primary volvulus and 90 secondary ones. The most frequent symptom was sudden abdominal pain. CT scan was the best diagnostic method with an accuracy of 83 per cent. Necrotic small bowel loops appeared in 46.5 per cent of the patients. Eighteen patients had postoperative complications (14%). Mortality rate was 9.3 per cent. A higher mortality is observed among patients with previous abdominal surgeries and cardiopathies. Necrotic loops are associated with higher mortality and incidence of surgical complications; patients with diabetes are associated with a higher incidence of necrotic loops. Cardiopathies are associated with more frequent medical and surgical complications. Recurrence rate was 3.9 per cent associated with simple devolvulation. Primary volvulus are more frequent among males and patients with diabetes. Jejunal location is associated with primary volvulus and these correlate with a higher incidence of necrotic loops. Primary volvulus presents a higher incidence of surgical complications. A bowel obstruction with sudden abdominal pain must be suspicious of small bowel volvulus. The main aim is to achieve an early diagnosis to prevent a necrotic small bowel. CT scan is the imaging test with the best diagnostic accuracy. Primary volvulus, the presence of necrotic loops, and patients with cardiopathies, diabetes mellitus, and with previous abdominal surgery are associated with a worse outcome.

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LEQUIME, J., e H. DENOLIN. "Nouvelles méthodes de diagnostic des affections cardiaques. Application à I‘étude des cardiopathies congénitales". Acta Medica Scandinavica 139, S259 (24 aprile 2009): 226. http://dx.doi.org/10.1111/j.0954-6820.1951.tb13261.x.

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Parat, S., e A. Giuseppi. "Pédiatre de maternité et prise en charge périnatale des cardiopathies de diagnostic anténatal". Archives de Pédiatrie 17, n. 6 (giugno 2010): 746–47. http://dx.doi.org/10.1016/s0929-693x(10)70090-7.

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Magontier, N., S. Cloarec, M. Vaillant, A. Jimenez, C. Paillet e A. Chantepie. "Incidence, répartition et performance du diagnostic anténatal des cardiopathies congénitales en Indre-et-Loire". Archives de Pédiatrie 5, n. 8 (agosto 1998): 946. http://dx.doi.org/10.1016/s0929-693x(98)80227-3.

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Bensemlali, M., F. Bajolle, J. Lebidois, L. Salomon e D. Bonnet. "SFP PC-61 – Dix ans de transfert in utero des cardiopathies congénitales de diagnostic anténatal". Archives de Pédiatrie 21, n. 5 (maggio 2014): 951. http://dx.doi.org/10.1016/s0929-693x(14)72211-0.

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Bensemlali, M., F. Bajolle, J. Lebidois, L. Salomon e D. Bonnet. "SFP CO-41 - Impact des anomalies extracardiaques sur le pronostic des cardiopathies congénitales de diagnostic anténatal". Archives de Pédiatrie 21, n. 5 (maggio 2014): 692. http://dx.doi.org/10.1016/s0929-693x(14)71952-9.

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Cloarec, S., N. Magontier, M. C. Vaillant, C. Paillet e A. Chantepie. "Prévalence et répartition des cardiopathies congénitales en Indre-et-Loire. Évaluation du diagnostic anténatal (1991–1994)". Archives de Pédiatrie 6, n. 10 (ottobre 1999): 1059–65. http://dx.doi.org/10.1016/s0929-693x(00)86979-1.

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Humeau, Clara, e Odile Sénécat. "Complications au long terme du diabète sucré chez le chien et le chat : signes d’appel, diagnostic et prise en charge". Le Nouveau Praticien Vétérinaire canine & féline 20, n. 85 (2023): 30–37. http://dx.doi.org/10.1051/npvcafe/2024010.

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En cas de diabète sucré mal équilibré ou diagnostiqué tardivement, des complications au long terme peuvent apparaître. Il s’agit le plus souvent d’atteintes oculaires, fréquemment rencontrées chez le chien (cataractes, rétinopathies, uvéites) ou neurologiques, plus souvent diagnostiquées chez le chat (polyneuropathie appendiculaire distale ou plus rarement neuropathie autonome). L’état hyperglycémique favoriserait également, comme chez l’Homme, le développement de néphropathies ou de cardiopathies, bien que la pathogénie ne soit pas encore bien élucidée. De nombreux examens complémentaires sont disponibles afin d’évaluer la présence de ces complications lors du diagnostic. L’insulinothérapie mise en place précocement permet de limiter l’apparition de ces complications, qui sont, une fois installées, généralement irréversibles. Les inhibiteurs de l’aldose réductase, enzyme intervenant dans la pathogénie d’apparition de certaines de ces complications, sont également à l’essai. D’autres traitements, médicaux ou chirurgicaux, sont parfois envisageables une fois les lésions déjà installées.

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Blais, C., e L. Rochette. "Tendances de la prévalence, de l'incidence et de la mortalité des cardiopathies ischémiques diagnostiquées et silencieuses au Québec". Promotion de la santé et prévention des maladies chroniques au Canada 35, n. 10 (dicembre 2015): 197–207. http://dx.doi.org/10.24095/hpcdp.35.10.02f.

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Introduction Parmi toutes les causes de décès d’origine cardiovasculaire, les cardiopathies ischémiques (CI) demeurent les plus importantes. Notre étude visait à définir les tendances de la prévalence et de l’incidence des CI au Québec ainsi qu’à déterminer la proportion de décès par CI qui n’avait aucun diagnostic antérieur de CI. Méthodologie Les tendances de la prévalence, de l’incidence et de la mortalité ont été examinées avec une étude populationnelle utilisant le Système intégré de surveillance des maladies chroniques du Québec, qui jumelle plusieurs fichiers médico-administratifs. Les données, recueillies auprès des Québécois de 20 ans et plus, sont présentées selon deux définitions de cas : 1) une définition validée et 2) une définition reposant sur l’addition des codes de décès liés aux CI afin d’estimer la proportion des décès sans diagnostic antérieur de CI comme indicateur de mort cardiaque subite (MCS). Résultats En 2012-2013, la prévalence brute des CI selon la première définition était de 9,4 % (593 000 personnes). Entre 2000-2001 et 2012-2013, la prévalence ajustée selon l’âge a augmenté de 14 %, avec une légère diminution depuis 2009-2010. Les taux d’incidence et de mortalité ajustés selon l’âge ont diminué de respectivement 46 % et 26 %, les taux bruts s’établissant à 6,9 pour 1 000 et à 5,2 % en 2012-2013. La proportion de décès identifiés uniquement grâce au décès par CI, soit l’indicateur de MCS, n’était significative que pour les cas incidents (0,38 pour 1 000 en 2009-2010) et elle a diminué au cours de la période à l’étude. Conclusion La prévalence des CI a eu tendance à diminuer au cours des dernières années et l’incidence comme la mortalité ont également diminué au Québec. La majorité des décès par CI touchent des patients ayant déjà reçu un diagnostic, seule une faible proportion des cas incidents n’ayant pas été préalablement identifiée.

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Durand, I., N. David, G. Blaysat e C. Marguet. "Diagnostic anténatal des cardiopathies congénitales dans une population à bas risque en Haute-Normandie : étude rétrospective de 2003 à 2007". Archives de Pédiatrie 16, n. 5 (maggio 2009): 409–16. http://dx.doi.org/10.1016/j.arcped.2009.02.013.

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Bonnefoy, R., J. Poinsot, M. C. Vaillant e A. Chantepie. "Évolution du diagnostic anténatal des cardiopathies congénitales entre 1991 et 2005 dans une population limitée au département d’Indre-et-Loire". Archives de Pédiatrie 18, n. 5 (maggio 2011): 512–17. http://dx.doi.org/10.1016/j.arcped.2011.02.013.

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Colle, Benjamin, Fabian Demeure, Julien Higny, Martin Benoit, Jean-Philippe Henry, Isabelle Michaux, Robaye Benoit et al. "Emerging Trends in Left Ventricular Thrombus: A Comprehensive Review of Non-Ischemic and Ischemic Cardiopathies, Including Eosinophilic Myocarditis, Chagas Cardiomyopathy, Amyloidosis, and Innovative Anticoagulant Approaches". Diagnostics 14, n. 9 (30 aprile 2024): 948. http://dx.doi.org/10.3390/diagnostics14090948.

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This comprehensive review explores the intricate aspects of left ventricular thrombus (LVT), a potential complication in both ischemic and non-ischemic cardiomyopathies. It provides a thorough understanding of left ventricular thrombus, revealing its uncommon incidence in the general population (7 cases per 10,000 patients), predominantly linked to ischemic heart diseases (ICMs) at an 80% prevalence rate. Diagnostic tools, notably transthoracic echocardiography (TTE) and cardiac magnetic resonance imaging (CMR), demonstrate varying sensitivity but remain indispensable in specific clinical contexts related to LVT as non-invasive diagnostic modalities. A detailed comparison between ICM patients and those with non-ischemic cardiomyopathy (NICM) who have left ventricular thrombus reveals subtle distinctions with significant clinical implications. This analysis underscores the importance of these imaging techniques in distinguishing between the two conditions. Additionally, we explored the occurrence of LVT in specific non-ischemic cardiomyopathies, including Takotsubo syndrome, hypertrophic cardiomyopathy, eosinophilic myocarditis, Chagas disease, cardiac amyloidosis, and several other conditions. The article further delves into anticoagulation strategies, thoroughly examining their impact on LVT regression and patient outcomes. Pharmacological interventions, with a focus on direct oral anticoagulants, emerge as promising alternatives; however, there is insufficient information on their efficiency and safety, especially in NICM population. In conclusion, this review highlights the complex nature of LVT, incorporating a range of etiopathogenic factors, diagnostic complexities, and evolving therapeutic approaches. It emphasizes the pressing need for ongoing research in this field.

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Kamendje Tchokobou, B., N. Coulon, P. Maragnes, M. Iselin e X. Lecoutour. "P13-2 Épidémiologie des cardiopathies congénitales dans le département du Calvados : circonstances du diagnostic, incidence et devenir de l’enfant, 1996-2000". Revue d'Épidémiologie et de Santé Publique 52 (settembre 2004): 135. http://dx.doi.org/10.1016/s0398-7620(04)99358-3.

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Idrissa, Hama. "Profile of Congenital Cardiopathies in Paediatric Departments A and B of the National Hospital Niamey National Hospital (Research article)". Journal of Clinical Research and Reports 11, n. 4 (5 ottobre 2022): 01–06. http://dx.doi.org/10.31579/2690-1919/267.

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Aim: The aim of this study was to determine the extent of congenital heart disease in the population of children, for a better management and prevention strategy. Materials and Methods: This was a descriptive and cross-sectional study over a period of 4 years 10 months from January 2016 to October 2020 (retrospective over 4 years and prospective over 10 months) at the National Hospital of Niamey; Were included in our study all patients aged 0 to 21 with congenital heart disease confirmed by cardiac ultrasound who were hospitalized or monitored externally. Our data were analyzed by Epi Info software in version 7.2.2.6. 24. Descriptive and analytical statistics were used: the mean with standard deviation (SD) (for normal distributive variations), odds ratio (OR) and the median (Me) for the description of asymmetric distributive values. The comparison of the proportions was also carried out; to do this we used the statistical test of chi2. The test is significant if p <0.05 Results: The gender ratio was 1.005 in favour of men. The median age of our patients was 16.8 months with extremes ranging from 0 months to 247 months, the most represented age group is 29 days to 24 months with 81.1%. The majority of our patients (62.4%) came from urban areas, parental consanguinity was present in 42.2% of cases. 55.3% of our patients had reported a notion of recurrent respiratory infection. Respiratory distress was found in 29.5% of cases, followed by fatigue during feedings (16.7%). Tachycardia was found in 72.2% of our patients, 49.6% were undernourished. Heart murmur was found in 80.3% of our patients, 4.4% had Down's syndrome. Cardiomegaly was found in 64.4% of our patients, 15.7% had pulmonary hypervascularization. CIV was found in 27.03% followed by T4F, CAV, and CIA with 20.39 respectively; 17.20 and 16.95%. Surgery was indicated in 68.3%. Anemia was found in 55% of our patients, 49.6% had hyperleukocytosis. Antibiotic treatment was started in 72.7% of cases, 31.2% had benefited from diuretics, 23.8% from iron supplementation, 10.3% was on beta blockers. 18.7% had received surgical treatment, PAH and endocarditis were found in 1 and 0.73% of cases, respectively. 34.1% were awaiting surgery. The recorded death rate was 27.3%. Conclusion: Congenital heart disease is becoming more and more frequent and constitutes a very important health problem in our pediatric departments. They are dominated by CIVs and T4s. The diagnosis and their management are still difficult due to the lack of diagnostic and therapeutic means.

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GACEM, Hocine, Fatima Hadia Oumammar, Ramata Dembele, Rachida Derghal e Amel Ahmane. "Evaluation of clinical pharmacy activity in tracking patients with ischemic myocardial disease". Batna Journal of Medical Sciences (BJMS) 2, n. 2 (30 dicembre 2012): 121–25. http://dx.doi.org/10.48087/bjmsoa.2015.2204.

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Introduction : L’intégration de pharmaciens cliniciens au sein des services cliniques s’avère indispensable pour lutter contre les problèmes d’évènements iatrogènes médicamenteux. Dans ce contexte, cette étude a été menée afin de décrire et analyser les risques liés aux prescriptions et d’évaluer la pertinence des interventions pharmaceutiques. Matériels et méthodes : Cette étude transversale, descriptive, a porté sur 119 patients atteints de cardiopathies ischémiques dans le service de cardiologie du CHU de Batna durant la période allant du 09/02/2014 au 24/04/2014. Les données personnelles des patients et celles liées au diagnostic et aux thérapeutiques étaient recueillies sur des fiches de questionnaire, les prescriptions analysées et les interventions rapportées sur des fiches d’interventions et cotées afin de déterminer leur impact. Résultats : La prévalence des interactions médicamenteuses était de 99,1% dont 59,8% sont du niveau à prendre en compte. Une ou plusieurs non conformités de prescription ont été signalées dans 47,9% des cas. 33 interventions pharmaceutiques ont été réalisées relevant 44 problèmes différents à la tête desquels se trouve l’inobservance du traitement et la présence d’indication non traitée. Les interventions consistaient principalement en l’ajout de médicament (52,3%) et ont été considérées à impact clinique significatif à 41,6%. Le taux d’acceptabilité de ces interventions est de 81,6%.

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Aversano, Lerina, Mario Luca Bernardi, Marta Cimitile, Debora Montano e Riccardo Pecori. "Characterization of Heart Diseases per Single Lead Using ECG Images and CNN-2D". Sensors 24, n. 11 (28 maggio 2024): 3485. http://dx.doi.org/10.3390/s24113485.

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Cardiopathy has become one of the predominant global causes of death. The timely identification of different types of heart diseases significantly diminishes mortality risk and enhances the efficacy of treatment. However, fast and efficient recognition necessitates continuous monitoring, encompassing not only specific clinical conditions but also diverse lifestyles. Consequently, an increasing number of studies are striving to automate and progress in the identification of different cardiopathies. Notably, the assessment of electrocardiograms (ECGs) is crucial, given that it serves as the initial diagnostic test for patients, proving to be both the simplest and the most cost-effective tool. This research employs a customized architecture of Convolutional Neural Network (CNN) to forecast heart diseases by analyzing the images of both three bands of electrodes and of each single electrode signal of the ECG derived from four distinct patient categories, representing three heart-related conditions as well as a spectrum of healthy controls. The analyses are conducted on a real dataset, providing noteworthy performance (recall greater than 80% for the majority of the considered diseases and sometimes even equal to 100%) as well as a certain degree of interpretability thanks to the understanding of the importance a band of electrodes or even a single ECG electrode can have in detecting a specific heart-related pathology.

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Saba, G. "Comorbidités somatiques et résistance thérapeutique". European Psychiatry 29, S3 (novembre 2014): 664. http://dx.doi.org/10.1016/j.eurpsy.2014.09.053.

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RésuméParmi les facteurs de résistance thérapeutique d’un épisode dépressif majeur (EDM), on peut évoquer d’emblée l’association aux pathologies somatiques, au premier rang desquelles figurent les affections endocriniennes, cardiovasculaires et métaboliques. Plusieurs d’entre elles sont d’ailleurs susceptibles d’engendrer la survenue d’un EDM, en pérenniser les manifestations cliniques, et conduire à la résistance aux traitements classiquement proposés dans cette indication. La co-occurrence d’une pathologie somatique et d’un EDM n’est pas une situation rare en pratique clinique quotidienne dans la mesure où elle concerne 25 % de la population hospitalisée pour pathologie somatique [1]. Des études longitudinales montrent que les EDM contemporains d’une pathologie somatique sont plus à risque d’évoluer vers la chronicité ou la résistance aux stratégies thérapeutiques standards que les EDM sans comorbidité somatique [2].Réciproquement, la dépression majeure est aujourd’hui reconnue pour accroître singulièrement le risque de développer un cancer, un trouble métabolique ou une pathologie cardiaque comme les cardiopathies ischémiques, avec un retentissement important sur l’évolution et le pronostic de la maladie somatique [3].Cette comorbidité, à l’origine d’une résistance croisée entre les deux pathologies, est fréquemment méconnue en pratique clinique, souvent du fait d’une attention sélectivement portée sur la pathologie ayant motivé la prise en charge, mais aussi en raison des difficultés diagnostiques liées à la superposition des troubles.Sur le plan thérapeutique, les implications sont considérables. En effet, un traitement antidépresseur bien conduit montre souvent une efficacité, non seulement en réduisant l’intensité des symptômes dépressifs, mais également en améliorant le cours évolutif de la pathologie somatique, ainsi que son pronostic [4]. Une meilleure connaissance de ces intrications s’avère donc indispensable de façon à permettre le traitement de la pathologie associée, mais aussi limiter l’impact négatif de cette dernière sur le diagnostic et l’évolution de l’affection primitivement reconnue.

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Liu, S., J. Rouleau, JA León, R. Sauve, KS Joseph e JG Ray. "Influence du diabète antérieur à la grossesse sur les anomalies congénitales au Canada entre 2002 et 2012". Promotion de la santé et prévention des maladies chroniques au Canada 35, n. 5 (luglio 2015): 85–91. http://dx.doi.org/10.24095/hpcdp.35.5.01f.

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Objectif Examiner l’influence du diabète antérieur à la grossesse sur la prévalence à la naissance des anomalies congénitales au Canada. Méthodologie Nous avons réalisé une étude en population chez l’ensemble des femmes ayant accouché à l’hôpital au Canada (hors Québec) entre avril 2002 et mars 2013, ainsi que chez leurs enfants nés vivants ayant un poids à la naissance d’au moins 500 grammes ou un âge gestationnel d’au moins 22 semaines. On a attribué les codes de diagnostic de la CIM-10 au diabète de type 1 ou de type 2 antérieur à la grossesse. L’association entre le diabète et l’ensemble des anomalies congénitales ainsi qu’avec les diverses catégories prises séparément a été estimée à l’aide des rapports de cotes ajustés et son influence a été calculée sous forme de pourcentage de risque attribuable dans la population (%RAP). Résultats Sur les 2 839 680 naissances vivantes, 118 892 nouveau-nés étaient atteints d’anomalies congénitales (41,9 pour 1 000). Même si la prévalence des anomalies congénitales est passée de 50,7 pour 1 000 naissances vivantes en 2002–2003 à 41,5 pour 1 000 en 2012–2013, le %RAP d’une anomalie congénitale liée au diabète antérieur à la grossesse est passé de 0,6 % (intervalle de confiance [IC] à 95 % : 0,4 à 0,8) à 1,2 % (IC à 95 % : 0,9 à 1,4). Plus précisément, le %RAP des cardiopathies congénitales est passé de 2,3 % (IC à 95 % : 1,7 à 2,9) à 4,2 % (IC à 95 % : 3,5 à 4,9) et celui des anomalies gastrointestinales de 0,8 % (IC à 95 % : 0,2 à 1,9) à 1,4 % (IC à 95 % : 0,7 à 2,6) au cours de la période étudiée. Conclusion En dépit de la diminution relative de la prévalence des anomalies congénitales au Canada, la proportion d’anomalies congénitales pouvant être attribuées au diabète maternel antérieur à la grossesse a augmenté. On recommande l’amélioration des initiatives en matière de soins préconceptionnels destinées aux femmes diabétiques.

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Guskova, N. K., L. Yu Vladimirova, E. A. Sycheva, A. A. Morozova, D. A. Rosenko, A. K. Donskaya, O. N. Selyutina, A. M. Skopintsev e N. V. Golomeeva. "Changes in the level of cardiomarkers in the development of acute myocardial infarction on the background of chemotherapy of a patient with tongue cancer". South Russian Journal of Cancer 2, n. 3 (8 settembre 2021): 48–54. http://dx.doi.org/10.37748/10.37748/2686-9039-2021-2-3-6.

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Cancer is one of the leading causes of death and disability worldwide. Timely diagnosis and the introduction of new effective treatments, including intensive radiation and chemotherapy regimens, have significantly improved survival forecasts in recent years. At the same time, the use of these types of treatment increases the risk of complications, one of which includes chemotoxic cardiopathies. In this regard, timely detection and treatment of complications from the cardiovascular system in patients receiving chemotherapy courses in combination with surgical methods of treatment is important. This paper presents an assessment of the significance of the use of cardiomarkers in the early diagnosis of acute myocardial infarction that developed during chemotherapy in a patient with tongue cancer with a complicated cardiac history. Patient M., 45 years old, was admitted for surgical treatment for cancer of the tongue St. IVA, T4aN1M0, cl. gr. 2. Planned laboratory and instrumental studies were performed. Contraindications for surgical treatment were not identified. A preoperative course of chemotherapy was performed, against the background of which the patient's condition worsened with symptoms of acute cardiopathy. A second ECG was urgently performed, as a result of which an increase in the ST segment in III, aVF was established, as well as a study of the concentration of cardiomarkers: highly sensitive troponin I, N-terminal propeptide of natriuretic hormone, creatine phosphokinase MB, myoglobin, the dynamics of changes in the level of which indicated the development of acute coronary syndrome. The complex application of diagnostic procedures, including the determination of the level of cardiomarkers, made it possible to timely diagnose the development of acute type 1 myocardial infarction in a patient with tongue cancer on the background of chemotherapy. When analyzing the entire array of clinical and laboratory data, the leading initiating factor that played a decisive role in the development of myocardial infarction in this case was, in our opinion, a preoperative course of polychemotherapy with paclitaxel and carboplatin, which have cardiotoxicity. Thus, the category of patients with an initial unfavorable background, due to a common malignant process and the presence of a history of cardiodisfunction, requires more careful preparation for preoperative courses of polychemotherapy, including cardiotropic therapy with mandatory monitoring of the level of the main cardiomarkers. The most significant changes were in the levels of creatine phosphokinase MB, troponin I, and myoglobin, which were recorded in the first hours of myocardial infarction. An association was found between an increase in troponin I concentration and an increase in the ST segment of the electrocardiogram.

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Guskova, N. K., L. Yu Vladimirova, E. A. Sycheva, A. A. Morozova, D. A. Rosenko, A. K. Donskaya, O. N. Selyutina, A. M. Skopintsev e N. V. Golomeeva. "Changes in the level of cardiomarkers in the development of acute myocardial infarction on the background of chemotherapy of a patient with tongue cancer". South Russian Journal of Cancer 2, n. 3 (6 settembre 2021): 48–54. http://dx.doi.org/10.37748/2686-9039-2021-2-3-6.

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Abstract (sommario):

Cancer is one of the leading causes of death and disability worldwide. Timely diagnosis and the introduction of new effective treatments, including intensive radiation and chemotherapy regimens, have significantly improved survival forecasts in recent years. At the same time, the use of these types of treatment increases the risk of complications, one of which includes chemotoxic cardiopathies. In this regard, timely detection and treatment of complications from the cardiovascular system in patients receiving chemotherapy courses in combination with surgical methods of treatment is important. This paper presents an assessment of the significance of the use of cardiomarkers in the early diagnosis of acute myocardial infarction that developed during chemotherapy in a patient with tongue cancer with a complicated cardiac history. Patient M., 45 years old, was admitted for surgical treatment for cancer of the tongue St. IVA, T4aN1M0, cl. gr. 2. Planned laboratory and instrumental studies were performed. Contraindications for surgical treatment were not identified. A preoperative course of chemotherapy was performed, against the background of which the patient's condition worsened with symptoms of acute cardiopathy. A second ECG was urgently performed, as a result of which an increase in the ST segment in III, aVF was established, as well as a study of the concentration of cardiomarkers: highly sensitive troponin I, N-terminal propeptide of natriuretic hormone, creatine phosphokinase MB, myoglobin, the dynamics of changes in the level of which indicated the development of acute coronary syndrome. The complex application of diagnostic procedures, including the determination of the level of cardiomarkers, made it possible to timely diagnose the development of acute type 1 myocardial infarction in a patient with tongue cancer on the background of chemotherapy. When analyzing the entire array of clinical and laboratory data, the leading initiating factor that played a decisive role in the development of myocardial infarction in this case was, in our opinion, a preoperative course of polychemotherapy with paclitaxel and carboplatin, which have cardiotoxicity. Thus, the category of patients with an initial unfavorable background, due to a common malignant process and the presence of a history of cardiodisfunction, requires more careful preparation for preoperative courses of polychemotherapy, including cardiotropic therapy with mandatory monitoring of the level of the main cardiomarkers. The most significant changes were in the levels of creatine phosphokinase MB, troponin I, and myoglobin, which were recorded in the first hours of myocardial infarction. An association was found between an increase in troponin I concentration and an increase in the ST segment of the electrocardiogram.

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Guido, Finazzi, Ruggeri Marco, Marconi Monica, Rodeghiero Francesco e Barbui Tiziano. "The Natural History of Idiopathic Erythrocythosis: A Cohort Study of 74 Patients." Blood 104, n. 11 (16 novembre 2004): 1506. http://dx.doi.org/10.1182/blood.v104.11.1506.1506.

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Abstract Patients with absolute erythrocytosis not due to a detectable cause and not fulfilling the criteria for diagnosis of polycythemia vera (PV) are descriptively classified as Idiopathic Erythrocytosis (IE). Based on scanty and retrospective data, this disease is considered to be an heterogeneous entity, including “early” PV, unrecognized secondary erythrocytosis and other miscellaneous conditions. However, appropriate prospective studies to evaluate the natural history of patients with IE are not available. We report here the results of a cohort study of 74 patients with IE (66 males, 8 females, median age 56 years, range 14–82) followed in two Italian institutions. By definition, at baseline all IE patients had increased hematocrit (median 54%, range 48–68%) and increased red blood cell mass (> 25% above mean normal predicted value), but normal leukocyte (median values 8.1 x 109/L, range 2.3–12) and platelet counts (median values 197 x 109/L, range 117–467), as well as normal erythropoietin level, arterial O2 saturation, chest X ray and abdominal ultrasound scanning (i.e. no splenomegaly). Granulocyte PRV-1 expression was also normal in 29 patients (39%) analyzed. At diagnosis, 12 patients (16%) reported a previous history of major thrombosis (7 ischemic cardiopathies, 4 cerebral ischemic events and 1 deep vein thrombosis). All IE patients were treated with phlebotomy to maintain a target hematocrit <45% and 24 patients (32%) were given aspirin, 100 mg/die, for previous thrombosis or microvascular symptoms. No cytotoxic drugs were given. The IE cohort was followed in the outpatient clinic with physical examination and full blood count at least every three months for a median period of 3.5 years (range 1–23). Twentythree patients (31%) were followed for more than 8 years. No patient was lost to follow-up. During the observation period, no disease potentially associated with secondary eryhtrocytosis emerged and no hematological transition into overt PV, myelofibrosis or acute leukemia occurred; two patients had a major thrombotic event (1 cerebral ischemia and 1 deep vein thrombosis) with an estimated incidence of thrombotic complications of 0.8% patient-year. The incidence of thrombosis was significantly lower than observed in 205 patients with overt PV followed during the same period in one of the two institutions (Bergamo, 3.49% patient-year, p<0.05). This study indicates that: a. the natural history of patients with IE, at least in the first years, is characterized by a remarkable and unexpected homogeneity without appearance of overt PV or diseases associated with secondary erythrocythosis; b. the diagnosis of IE identifies a group of absolute erythrocythoses at lower risk of thrombotic complications not requiring cytotoxic drug therapy; c. the diagnostic work-up of patients with absolute erythrocythosis should carefully distinguish IE from PV because the natural history and management of the two diseases is different.

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Kabanda, Eugene, e Et Al. "Cardiomyopathie ischémique liée à l’infection au VIH et ses complications cardiovasculaires : à propos d’un cas enregistré à Bujumbura". Revue Malienne d'Infectiologie et de Microbiologie 17, n. 1 (30 aprile 2022): 61–64. http://dx.doi.org/10.53597/remim.v17i1.2228.

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La cardiopathie ischémique est fréquemment rencontrée chez les personnes infectées par le VIH. Cependant, les complications thromboemboliques sont rares. Nous rapportons une observation d’un homme admis en hospitalisation pour cardiomyopathie ischémique liée au VIH sur terrain alcoolo-tabagique. L’échographie cardiaque a montré la présence de thrombi dans les deux ventricules. Il décéda après une semaine d’hospitalisation dans un tableau faisant évoquer une embolie pulmonaire. L’objectif de cette observation est de montrer l’intérêt du diagnostic précoce de cardiomyopathie ischémique liée au VIH enfin de prévenir ses complications

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Santos, Luciano De Oliveira, Erik Lima, Felipe Favaro Capeleti, Rafael Eidi Goto, Homero José de Farias e. Melo e Leandro Nobeschi. "Avaliação do perfil dosimétrico do setor de hemodinâmica / Hemodynamics sector’s dosimetric profile evaluation". Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 66, n. 1u (24 maggio 2021): 1. http://dx.doi.org/10.26432/1809-3019.2021.66.010.

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Introdução: Os avanços tecnológicos das últimas décadas permitiram que a cardiologia intervencionista se expandisse visivelmente propiciando o diagnóstico e terapêutica de cardiopatias através de procedimentos médicos pouco invasivosguiados por imagens radiológicas de escopia. Devido à necessidade de aproximação ao paciente e ao tubo de raios-X durante todo o procedimento existe um risco potencial para o aumento da dose nos IOEs. Objetivo: Traçar o perfil dosimétrico da sala de hemodinâmica durante um procedimentopadrão utilizando-se medidores de alta precisão. Método: A dosagem de radiação foi realizada no serviço de Hemodinâmica da Santa Casa de Misericórdia de São Paulo que utiliza um equipamento modelo MAVIG INNOVA IGS 5 da marca General Electrie-GE e no Hospital Santa Isabel, que utilizaum equipamento modelo ALLURA XPER FD 20 da marca PHILIPS. A medição consistiu em observar alterações na dose acumulada principalmente nos pontos em que se concentram os profissionais durante os procedimentos, quando dainterposição de barreira plumbífera através da distribuição da dose nestes pontos. Resultados: O estudo mostrou que a dose pode ser reduzida em até 90% com a interposição da barreira plumbífera de proteção. Foi possível observar a redução de 75% da dose ao aplicarmos a lei do inverso do quadrado da distância nos principais pontos estudados. Conclusão: O uso de aparatos de proteção proporcionou diminuir a alta taxa de dose e a probabilidade de ocorrência dos efeitos biológicos da radiação ionizante.Palavras-chave: Hemodinâmica, Exposição ocupacional, Proteção radiológica, Raios X, Radiologia intervencionistaABSTRACTIntroduction: The technological advances of the last decade allowed the intervencionist cardiology to expand visibly providing the diagnostic and therapeutic of cardiopathies through less invasive medical procedures guided by radiological images of endoscopy. Due to the need for the presence of the patient and the x-ray tube during all the procedure a potencial risk exist in the increase of the dose for the Occupational Exposed Individual (IOEs). Objective: Trace a dosimetric profile of the hemodynamic room during the standard procedure using measuring equipments of high precision. Method: Radiation dosing was performed at the Hemodynamics Service of Santa Casa de Misericórdia de São Paulo, which uses a MAVIG INNOVA IGS 5 model equipment from General Electrie-GE and at Hospital Santa Isabel, which uses an ALLURA XPER FD 20 model equipment. PHILIPS brand. The measurement consisted ofobserving changes in the accumulated dose, mainly in the points where the professionals are concentrated during the procedures, when the lead barrier is interposed through the dose distribution in these points. Results: The studyshowed that the dose can be reduced by up to 90% with the interposition of the protective lead barrier. It was possible to observe a 75% reduction in the dose when applying the inverse law of the square of the distance in the main pointsstudied. Conclusion: The use of protective devices has reducedthe high dose rate and the likelihood of the biologicaleffects of ionizing radiation.Keywords: Hemodynamics, Occupational exposure, X rays,Radiation protection, Radiology Interventional.

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Bonnet, D., D. Sidi, P. Souillard, I. Szezepanski, J. Kachaner, A. Munnich e S. Lyonnet. "Diagnostic rapide de la microdélétion interstitielle du chromosome 22 chez les nouveau-nés ayant une cardiopathie conotruncale". Archives de Pédiatrie 3, n. 7 (luglio 1996): 735–36. http://dx.doi.org/10.1016/0929-693x(96)87112-0.

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35

Khoshnood, B., C. de Vigan, V. Vodovar, J. Goujard, A. Lhomme, D. Bonnet e F. Goffinet. "Évolution du diagnostic prénatal, des interruptions de grossesse et de la mortalité périnatale des enfants avec cardiopathie congénitale". La Revue Sage-Femme 5, n. 5 (novembre 2006): 249–58. http://dx.doi.org/10.1016/s1637-4088(06)76057-6.

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Khoshnood, B., C. de Vigan, V. Vodovar, J. Goujard, A. Lhomme, D. Bonnet e F. Goffinet. "Évolution du diagnostic prénatal, des interruptions de grossesse et de la mortalité périnatale des enfants avec cardiopathie congénitale". Journal de Gynécologie Obstétrique et Biologie de la Reproduction 35, n. 5 (settembre 2006): 455–64. http://dx.doi.org/10.1016/s0368-2315(06)76417-1.

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Villemain, O., A. Bretonneau e H. Lucron. "SFP P-003 – Evaluation de deux systèmes de codages de cardiopathies congénitales (IPCCC, ACC-CHD) sur une série de diagnostics anténataux". Archives de Pédiatrie 21, n. 5 (maggio 2014): 713. http://dx.doi.org/10.1016/s0929-693x(14)71973-6.

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38

Babakhouya, A., H. Elmoqaddem, A. Elouali, H. Zahiri, S. Anane, A. Ghanam e M. Rkain. "PROFILE OF ISCHEMIC STROKE IN CHILDREN: EXPERIENCE OF THE UNIVERSITY HOSPITAL CENTER OF OUJDA". International Journal of Advanced Research 12, n. 06 (30 giugno 2024): 1061–66. http://dx.doi.org/10.21474/ijar01/18973.

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Ischemic strokes (IS) in children are rare but critical, presenting unique challenges due to age-specific factors. Defined by the American Heart Association as episodes of neurological dysfunction caused by focal infarctions, IS can lead to severe outcomes if not promptly addressed. Despite their rarity, pediatric IS requires careful management, complicated by the lack of validated treatment data for children. This study from the University Hospital Center of Oujda examines the management of acute IS in children, analyzing epidemiological aspects, clinical presentations, and therapeutic approaches. Results : 1. Population: 29 children, average age 3.5 years, slight male predominance (sex ratio: 1.2). 2. Consultation Delay: 14% were seen within 24 hours 50% after 7 days. 3. Symptoms: Motor deficit was the most common (82.7%). 4. Diagnostics: CT confirmed IS in 85% of cases MRI established etiological diagnosis in 51.8%, showing sylvian artery involvement in all patients. 5. Etiologies: Embolic cardiopathies (31.03%), vasculopathies (20.06%), and others such as hypertension and neurofibromatosis. 6. Treatments: Symptomatic management, motor physiotherapy, aspirin, and heparin. 7. Outcomes: 74% had complete regression of motor deficits, 20.6% had partial regression, and there were two deaths due to cardiogenic shock. The study underscores the need for a multidisciplinary approach to effectively manage IS in children and improve clinical outcomes.

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Cachera, D., F. Balen e S. Charpentier. "Patients présentant un syndrome coronarien aigu avec sus-décalage du segment ST admis en structure d’urgence après régulation par un Centre 15". Annales françaises de médecine d’urgence 9, n. 5 (30 giugno 2019): 284–88. http://dx.doi.org/10.3166/afmu-2019-0167.

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Introduction: La cardiopathie ischémique est une des principales causes de mortalité en Europe. Cette mortalité importante est l’apanage particulier des syndromes coronariens avec élévation du segment ST (SCA ST+). Si la prise en charge préhospitalière de ces patients (de l’appel à la table de coronarographie) est sous la responsabilité des Samu, certains patients échappent à la filière malgré un appel au Centre 15. Notre objectif était de décrire ces patients porteurs d’un SCA ST+, admis en structure d’urgence (SU) après régulation par un Centre 15.Méthode: Il s’agit d’une étude observationnelle de cohorte rétrospective incluant tous les patients admis en SU du CHU de Toulouse du 1eravril 2015 au 31 janvier 2017 avec un diagnostic final de SCA ST+.Résultats: Sur les 139 patients qui ont été admis en SU pour SCA ST+, 96 (69 %) avaient contacté le Centre 15. Les dossiers de 89 patients ont été analysés. On retrouve une importante proportion de patientes de plus de 75 ans, qui représentent un quart de la population. Seulement 30 patients (34 %) présentaient une douleur typique.Discussion: Notre étude retrouve un taux de douleurs atypiques et une proportion de femmes âgées plus importante que la littérature portant sur la description des patients porteurs de SCA ST+. Ces atypies de présentation peuvent expliquer la difficulté à réguler et orienter ces patients.

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Doskina, E., e A. Ametov. "Heart diseases (angina pectoris, syndrome X and climacteric menopaysal cardiopathia) limited by estrogen deficiency of menopausal women and differential diagnostic search". Diabetes Research and Clinical Practice 50 (settembre 2000): 347–48. http://dx.doi.org/10.1016/s0168-8227(00)81186-9.

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Lix, L. M., M. S. Yogendran, S. Shaw, C. Burchill, C. Metge e R. Bond. "Sources de données des populations utilisées en surveillance des maladies chroniques". Maladies chroniques au Canada 29, n. 1 (2008): 34–42. http://dx.doi.org/10.24095/hpcdp.29.1.04f.

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Dans cette étude, on a estimé la concordance entre les données des populations administratives et les données des populations d'enquête lorsqu'il s'agit de déterminer les cas d'arthrite, d'asthme, de diabète, de cardiopathie, d'hypertension et d'accident vasculaire cérébral. Des définitions de cas de maladies chroniques, qui variaient de par la source des données, le nombre d'années de données et les codes de diagnostic et de médicaments prescrits employés, ont été élaborées à partir des données administratives du Manitoba. Un recoupement a ensuite été fait entre ces données et celles tirées de l'Enquête sur la santé dans les collectivités canadiennes. La concordance entre ces deux sources de données, estimée par le coefficient κ, a été calculée pour chaque définition de cas, et les différences ont été testées. Les variables socio-démographiques et les variables liées à la comorbidité en lien avec la concordance ont été testées au moyen d'une régression logistique pondérée. C'est pour le diabète et l'hypertension que l'on a observé la concordance la plus élevée, et pour l'arthrite que l'on a observé la concordance la plus faible. Les éléments de la définition de cas qui contribuaient à la concordance la plus élevée entre les deux sources de données des populations variaient selon les maladies chroniques. Il est probable que les données administratives et les données d'enquête concordent peu dans le cas des affections qui sont difficiles à diagnostiquer, mais cette concordance est aussi influencée par les caractéristiques socio-démographiques et l'état de santé des individus. Toute définition de cas de maladie chronique fondée sur des données administratives devrait être accompagnée d'une justification du choix de chacun de ses éléments.

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Mendoza, Alejandro Arias, Emelí Estrada Pérez, Francisco Vázquez Martin, Jessica Arlene Avalos, Mauricio Emmanuel Umaña Reyes e Teresa Jannete Ortega Valls. "Comparative Assessment of Echocardiography and Magnetic Resonance Imaging in the Evaluation of Structural Cardiopathies in Adults: A Comprehensive Analysis". INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES 03, n. 10 (30 ottobre 2023). http://dx.doi.org/10.47191/ijmscrs/v3-i10-63.

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Cardiovascular diseases, specifically structural cardiopathies, continue to pose a significant burden on global healthcare systems. The accurate assessment of these conditions in adults demands precise and reliable imaging modalities. This article presents a comprehensive exploration of the role of two prominent diagnostic tools, echocardiography and magnetic resonance imaging (MRI), in the evaluation of structural cardiopathies in the adult population. We scrutinize the clinical utility, advantages, limitations, and diagnostic accuracy of both imaging techniques, shedding light on their respective roles in the clinical decision-making process. Furthermore, we delve into recent advancements and emerging trends in echocardiography and MRI, highlighting the potential synergistic use of these modalities to optimize the diagnostic and therapeutic approach to structural cardiopathies in adults. The findings from this review will contribute to enhancing clinical practice and patient outcomes in the management of these intricate cardiovascular conditions.

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Baptistella, Amanda, Ana Júlia A. Rossato, Beatriz C. de Gusmão, Carolina M. Cunha, Luiza F. Trafane e Paulo C. M. Colbachini. "Case report: Diagnostic and therapeutic challenges of fungal endocarditis by Trichosporon asahii in a child with congenital heart defects". Frontiers in Pediatrics 11 (6 ottobre 2023). http://dx.doi.org/10.3389/fped.2023.1200215.

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Backgroundpatients with congenital cardiopathies are the main group at risk for infective endocarditis (IE) in the pediatric population. Fungal etiology is responsible for 2%–4% of all IEs, and the Trichosporon genus is an increasingly prevalent cause of infections in human beings.Case presentationWe describe a 9-year-old male with multiple surgical procedures to correct congenital cardiopathy defects, including insertion of RV-PA conduit, who was admitted due to suspicion of pneumonia and needed a surgical approach after being diagnosed with a mycotic pseudoaneurysm in the right ventricle’s outflow tract, with dilation of the RV-PA conduit. The conduit was removed and antifungal treatment was started with Voriconazole after the agent was identified (T. asahii), with satisfactory therapeutic response. Approximately 4 years later, the patient was readmitted, presenting with intermittent fever, associated with nocturnal diaphoresis, dry cough, anxiety and chest pain. Vegetations consistent with T. asahii were evidenced in the RV-PA conduit, and a surgical approach was once again necessary.Discussiondiagnostic methods and treatment of T. asahii endocarditis aren't yet standardized, and recurrent surgical approaches are needed due to the inefficacy of antifungal treatment.

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Mouliade, C., F. Dépret, B. Rosenbaum e V. Mallet. "L’hépatite hypoxique : ce que le réanimateur doit savoir". Médecine Intensive Réanimation, 2019. http://dx.doi.org/10.3166/rea-2019-0125.

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L’hépatite hypoxique est secondaire à une inadéquation entre les besoins hépatiques en oxygène et les apports sanguins. Elle est caractérisée par une augmentation rapide et transitoire de l’activité des transaminases sériques, prédominant souvent sur l’aspartate aminotransférase, chez un patient avec une ou plusieurs comorbidité(s), en particulier cardiaque(s). Le diagnostic est clinicobiologique et ne nécessite pas, en général, d’examen d’imagerie ou d’anatomopathologie. La lésion histologique sous-jacente est une nécrose de la zone centrale du lobule hépatique. L’hépatite hypoxique est souvent associée à une insuffisance rénale aiguë. Les facteurs de risque sont les cardiopathies favorisant la congestion hépatique, les hypoxémies, les altérations de lamicrocirculation hépatique, telles qu’on les observe au cours de la cirrhose. La prise en charge repose sur la correction de l’événement aigu et la restauration d’une perfusion et d’une oxygénation hépatique appropriées. Le pronostic est sombre avec une mortalité proche de 50 % et dépend essentiellement du délai de prise en charge de l’événement causal. Il est classique d’observer un syndrome de cholestase après une hépatite hypoxique résolutive. La lésion sous-jacente, encore mal comprise, est probablement une ischémie des petites voies biliaires intrahépatiques qui peut conduire, parfois, à des cholangites sclérosantes secondaires. L’objectif de cet article est de fournir au réanimateur l’ensemble des outils lui permettant d’identifier les situations à risque d’hépatite hypoxique et d’en faire le diagnostic le plus précocement possible afin de mettre en œuvre les mesures nécessaires.

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Grimaldi, Céline, Fabrice Michel e Michel Panuel. "Echographie pulmonaire en réanimation pédiatrique : revue des connaissances en 2020". Médecine Intensive Réanimation, 8 dicembre 2020. http://dx.doi.org/10.37051/mir-00051.

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L’échographie pulmonaire (EP) s’est considérablement répandue en réanimation adulte mais son utilisation néonatale et pédiatrique, bien que croissante, reste plus limitée et la radiographie thoracique demeure l’examen de première ligne dans la plupart des centres. L’objectif de cette revue est de faire le point sur les études menées spécifiquement en réanimation pédiatrique, afin de présenter les connaissances déjà établies, les avantages et les limites de l’EP. Après un point sur son utilisation dans les pathologies néonatales et communautaires pédiatriques, nous abordons les utilisations spécifiques à la réanimation de l’enfant. L’EP présente un triple intérêt de diagnostic d’urgence, de guide aux procédures thérapeutiques et de suivi évolutif en temps réel ou différé. En néonatologie, elle aide à identifier l’étiologie des détresses respiratoires immédiates et secondaires et la gestion des détresses vitales. En pédiatrie communautaire, elle est utile au diagnostic de pneumonie et de bronchiolite et à la détection de complications. En réanimation pédiatrique, elle permet la mise en évidence des pneumopathies acquises sous ventilation mécanique (PAVM) et l’évaluation et le suivi du recrutement alvéolaire notamment dans le syndrome de détresse respiratoire aigüe (SDRA) ou les atélectasies péri opératoires. En combinaison avec le monitorage hémodynamique, elle aide à la surveillance des patients à risque d’oedème pulmonaire notamment dans les cardiopathies ou les sepsis. Enfin elle détecte rapidement les complications pulmonaires de réanimation ou post-opératoires, les atteintes thoraciques traumatiques et certaines causes potentiellement réversibles d’arrêt cardiaque. La publication récente des recommandations internationales pédiatriques et néonatales sur l’échographie d’urgence pourrait encourager sa diffusion dans la pratique courante.

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Santos, Juliana Godoy, Ellen Ronara de Jesus Franco, Eduarda Bagini Fliegner, Jullia de Pinho Borba, Marlon Ribeiro, Edson Moleta Colodel, Thais Oliveira Morgado e Pedro Eduardo Brandini Néspoli. "Myxomatous Degeneration of Atrioventricular Valves in a Crab-eating fox (Cerdocyon thous) - Echodopplercardiography Diagnosis". Acta Scientiae Veterinariae 50 (11 marzo 2022). http://dx.doi.org/10.22456/1679-9216.114524.

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Background: The myxomatosis degeneration is a degenerative cardiac valve disease, with a higher incidence in male and senile canids. The diagnosis is made by a doppler echocardiography exam. Although there are few reports on the occurrence of cardiopathies in wild dogs (Cerdocyon thous), some studies on their cardiological parameters can be found. Considering this, and knowing that the cardiopathies in wild canids are common post mortem findings, the objective of this study is to describe the echocardiography diagnosis of a case of myxomatous degeneration of the atrioventricular valves in 1 wild dog (Cerdocyon thous) living in captivity.Case: It was treated at the Diagnostic Imaging Department of the Veterinary Hospital of the Federal University of Mato Grosso (HOVET-UFMT), 1 wild dog (C. thous), male, living in captivity with approximately 10-year-old, directed by the Center of Medicine and Research in Wild Animals of Cuiabá, to perform echocardiography exam. The patient was submitted to anesthesia for proper examination, which was used Esaote® machine model MyLabFive VET with sector scan transducer (4.0 -7.5 MHz). The longitudinal, transverse and apical scan planes were obtained through left and right parasternal windows. The evaluation of M mode exposed ejection fraction and shortening increased, of 81% and 47%, respectively, however it showed no increase in systolic and diastolic values of left ventricle, nor in right cavities on subjective evaluation. The relation between the left atrium (LA) and the aorta (Ao) remained normal, at 1.2 mm, with dimensions of 13.4 mm from the AO and 16.3 mm from LA, compatible with species parameters or domestic canines. The atrioventricular valves showed thickening and irregularities in their cusps, with great intensity in the left atrioventricular valve (LAV). The Doppler mode analysis revealed a turbulent systolic flow into the left atrium and right atrium, constituting transvalvular LAV and right atrioventricular valve- (RAV) regurgitation, both observed through the blood flow in colored Doppler and measured through the reflux velocity of 4.02 m/s of LAV and 2.17 m/s of RAV by the continuous Doppler, showing insufficiency of intense degree of LAV and moderate degree of RAV, no evidence of pulmonary hypertension. On the other hand, the relation between wave E and wave A (E/A) was 1.0, with increased transvalvular velocities and values of 0.95 m/s for wave E and A. The isovolumetric mitral relaxation time was approximately 76 m/s. The value of the pressure derivative (dp) in relation to time (dt) dp/dt measured from the LAV reflux was 1257 mmHg, within the limit considered normal for canines. Four months after the diagnosis, the patient died due to complications of chronic renal failure.Discussion: Despite being a commonly diagnosed pathology in domestic canids, the myxomatous degeneration of atrioventricular valves is still little reported in wild canids. The evaluation of the results showed that although there was severe LAV regurgitation, there was no hypertrophy or compensatory dilation of the left cavities. However, there was a compensatory increase in the shortening fraction together with the ventricular relaxation deficit. The diagnosis of this condition in Cerdocyon thous demonstrates that the pathology can affect animals of advanced age and that its incidence needs to be determined in these captive species, in order to understand the real impact of this disease in these populations. Keywords: cardiopathies, cardiac valve disease, degenerative disease, cardiological parameters, wild dog. Título: Degeneração mixomatosa das válvulas atrioventriculares em cachorro-do-mato (Cerdocyon thous) - diagnóstico ecocardiográfico Descritores: cardiopatias, doença valvular cardíaca, doença degenerativa, parâmetros cardiológicos, canídeo selvagem.

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Torres, Ronaldo, e Tiago Torres. "A Brazilian Neonatal Unit's Experience with Functional Echocardiography and Diagnostic Findings in Congenital Heart Disease". Medical Research Archives 12, n. 2 (2024). http://dx.doi.org/10.18103/mra.v12i2.5165.

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Introduction: The diagnosis of congenital heart diseases is a challenge for pediatricians due to the diversity of clinical presentations and symptoms, just like several other diseases prevalent in the neonatal period. Often the diagnosis is established during the gestation period, sometimes the hypothesis is formulated by neonatal screening. However, several cases will require clinical suspicion from the pediatrician. Given the possibility of this diagnosis, the evaluation of the infant cardiologist is essential. Unfortunately, this professional is not always readily available. In the intensive care units, health professionals use heart rate, blood pressure, capillary refill, urinary output and acid-base balance for hemodynamic analysis. These data are significant, but nonspecific. Thus, functional echocardiography can improve hemodynamic evaluation with positive impact on diagnosis. Our objective was to conduct a retrospective analysis of hospitalizations in a Brazilian neonatal unit, with the goal of identifying the diagnoses of congenital heart diseases made by a researcher using functional echocardiography, from July 2015 to September 2017, having as inclusion criteria; clinical manifestations of distress or respiratory failure, characterized by tachypnea, signs of dyspnea, need for oxygen therapy or ventilatory support and/or hemodynamic instability, characterized by tachycardia, cyanosis, cold extremities, prolonged capillary filling time, fine pulses and/or hypotension, low urinary output. Results: During the 26 months of the study, 362 neonates were hospitalized. Of these, 223 were included in the research for presenting cardiorespiratory manifestations. We observed three cases of obstructive shock related to cardiac tamponade, 18 cases of congenital heart disease, five cases of hypertrophic myocardiopathy, seven cases of myocardial dysfunction not related to structural heart disease, 46 cases of neonatal persistent pulmonary hypertension and 27 cases of patent ductus arteriosus (six with hemodynamics repercussion). Conclusions: The results showed functional and/or anatomical changes in 105 patients analyzed (46.7%), identified a diversity of structural cardiopathies, improved hemodynamic evaluation with impact on the therapeutic approach. While using functional echocardiography in neonates, clinicians should be aware that undiagnosed critical congenital heart defects can present during this period. They should acknowledge the limitations of skills, and it should not be used as a screening tool for diagnosing or excluding congenital heart defects. A patient with a suspected critical congenital heart defect should be quickly referred to a pediatric cardiologist, even if this implies out-of-hospital patient’s transportation. We assume that the systematic implementation of this technology by the medical team can improve diagnostic accuracy, which can positively impact the therapy used. Keywords: Critical care, neonatology, ultrasonography, echocardiography, point-of-care systems, cardiac tamponade, hypertension pulmonary, heart defectal congenits.

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Balmer, Christian, Lydie Beauport, Olivier Niesse e Romaine Arlettaz. "Screening néonatal des cardiopathies congénitales critiques par saturométrie : le POx screening". Paediatrica, 10 aprile 2019. http://dx.doi.org/10.35190/paediatrica.online.f.2019.

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Pourquoi un dépistage des cardiopathies congénitales ? Le screening a pour but d’identifier les nouveau-nés souffrant de cardiopathies susceptibles de mettre leur vie en danger. Ces enfants se développent certes normalement pendant la grossesse, mais se péjorent subitement après la naissance, à cause des modifications physiologiques cardio-respiratoires et de la fermeture du canal artériel. Ces cardiopathies étant, dans de nombreux cas, incompatibles avec la survie sans intervention invasive au cours des 4 premières semaines de vie, elles sont définies comme étant des cardiopathies congénitales critiques. Elles comprennent essentiellement les diagnostics répertoriés dans le tableau 1.

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TALEB BENDIAB, Nabila Soufi. "Une double discordance cardiaque complexe décompensée, à propos d’un cas et revue de la littérature". Journal de la faculté de médecine d'Oran 6, n. 2 (2022). http://dx.doi.org/10.51782/jfmo.v6i2.176.

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La double discordance est une cardiopathie congénitale complexe extrêmement rare, elle se caractérise par une discordance auriculo-ventriculaire suivie d’une autre discordance ventriculo-artérielle. Son diagnostic est posé généralement à l’âge adulte par des examens d’imagerie. Son pronostic dépend essentiellement des autres malformations congénitales cardiaques associées, des arythmies et des troubles de la conduction, ainsi que de la fonction systolique du ventricule droit en position systémique. Nous rapportons le cas d’un patient âgé de 23 ans, porteur d’une cardiopathie congénitale complexe cyanogène. Il s’agit d’une double discordance associée à une large communication interventriculaire sous aortique avec un shunt inversé et une hypoplasie de l’artère pulmonaire. Ce diagnostic a été confirmé par l’imagerie multimodale. Non opéré, le patient a vu son stade fonctionnel s’aggraver rapidement avec une dyspnée qui est passée d’un stade I à un stade III-IV de la New York Heart Association (NYHA), et apparition de signes hypoxiques et congestifs. A travers cette observation, nous avons précisé les caractéristiques anatomocliniques de cette cardiopathie congénitale complexe cyanogène, son exploration, ses options thérapeutiques, ainsi que le rôle péjoratif de son association avec d’autres malformations congénitales.

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Nishimoto, Ticiane, Eric Magalhães de Moraes, Eduardo Ryoiti Tatebe, Guilherme Do Espírito Santo Silva e Paula Cristina Souto de Camargo. "Atendimento ambulatorial dos pacientes em terapia de anticoagulação de um hospital cardiológico de alta complexidade do município de São Paulo". Revista de Administração em Saúde 19, n. 74 (18 marzo 2019). http://dx.doi.org/10.23973/ras.74.158.

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RESUMONo contexto da cardiologia, os pacientes portadores de cardiopatias em uso de terapia de anticoagulação frequentemente realizam o exame de tempo de protrombina (TP) para monitorar o grau de anticoagulação do sangue e manutenção do TP para acompanhamento da medicação anticoagulante. O objetivo do projeto foi analisar e propor intervenções de melhoria no processo deste atendimento ambulatorial para a realização do exame de TP dos pacientes em uso de terapia de anticoagulação, em um hospital público universitário de alta complexidade, especializado em cardiologia, pneumologia e cirurgias cardíaca e torácica, localizado na cidade de São Paulo. Trata-se de um estudo de caso e os dados coletados foram analisados quantitativamente em caráter exploratório, transversal e descritivo, sendo retrospectivo referente ao período de novembro de 2016 e abril de 2017. Os dados foram obtidos através de fontes internas da instituição, além de análise observacional do local e pareceres das partes envolvidas, apresentados como fase diagnóstica e proposta de intervenção. De acordo com os dados coletados, foram realizados em média 4750 exames de TP por mês, representando 25% do volume de atendimentos ambulatoriais da instituição. Aproximadamente 55% dos pacientes estavam fora da faixa terapêutica, apresentando baixa eficácia do controle de anticoagulação. Todos os pacientes após a realização do exame de TP, passam por uma consulta breve de avaliação do médico, para analisar o resultado do exame e ajustar a medicação se necessário (ponto peculiar deste exame), apresentando um cuidado fragmentado por especialidade e centrado no atendimento médico. A partir dos dados observados, diagnóstico situacional, levantamento bibliográfico e benchmarking realizado em um hospital especializado em cardiologia de São Paulo, foi recomendada a implantação de um serviço centralizado com a criação de um “ambulatório de anticoagulação”, incluindo serviços como: sistematização eletrônica específica para registro do exame de TP e conduta terapêutica; criação da tabela de anticoagulação do paciente; utilização de testes rápidos de TP do tipo; atuação da equipe multiprofissional com destaque para ações de educação em saúde e auto cuidado; serviço para dúvidas e orientações; Avaliação para introdução de novas medicações que não exijam o controle do INR.Palavras-chave: ambulatório, cardiologia, anticoagulação, tempo de protrombina. ABSTRACTIn the context of cardiology, patients with cardiopathies using anticoagulation therapy often perform the prothrombin time (PT) test to monitor the degree of blood anticoagulation and maintenance of PT to monitor anticoagulant medication. The objective of the project was to analyze the process of this outpatient care to perform the PT examination of patients undergoing anticoagulation therapy in a high complexity public university hospital specialized in cardiology, pulmonology and cardiac and thoracic surgeries, located in the city from Sao Paulo. It is a case study and the data collected were quantitatively analyzed in an exploratory, cross-sectional and descriptive character, being retrospective for the period of November 2016 and April 2017. Data were obtained through internal sources of the institution, in addition to observational analysis of the site and opinions of the parties involved, presented as diagnostic phase and intervention proposal. According to the data collected, an average of 4750 PT examinations per month were performed, representing 25% of the institution's outpatient services. Approximately 55% of the patients were out of the therapeutic range, presenting low efficacy of anticoagulation control. All patients after the PT exam, undergo a brief evaluation of the physician, to analyze the result of the examination and adjust the medication if necessary (peculiar point of this examination), presenting a care fragmented by specialty and focused on the care doctor. Based on the observed data, situational diagnosis, bibliographic survey and benchmarking carried out in a specialized hospital in cardiology of São Paulo, it was recommended the implementation of a centralized service with the creation of an "anticoagulation clinic", including services such as: Specific electronic systematization for recording PT and therapeutic management; creation of the patient's anticoagulation table; use of rapid type TP tests; performance of the multiprofessional team with emphasis on health education and self-care actions; service for questions and directions; Evaluation for the introduction of new medications that do not control INR.Keywords: ambulatory, cardiology, anticoagulation, prothrombin time.

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